Pyrimidine-2-carbonitrile
Title | Journal |
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3D-QSAR and molecular docking studies of 2-pyrimidinecarbonitrile derivatives as inhibitors against falcipain-3. | Bioorganic & medicinal chemistry letters 20111201 |
Unprecedented copper(I)-catalyzed in situ double cycloaddition reaction based on 2-cyanopyrimidine. | Dalton transactions (Cambridge, England : 2003) 20110607 |
Poly[(μ(2)-nitrato-κO:O')(μ(2)-pyrimidin-ium-2-carboxyl-ato-κO:O')lithium(I)]. | Acta crystallographica. Section E, Structure reports online 20110601 |
Mining a cathepsin inhibitor library for new antiparasitic drug leads. | PLoS neglected tropical diseases 20110501 |
Top-hits for H1N1pdm Identified by Virtual Screening Using Ensemble-based Docking. | PLoS currents 20110103 |
Synthesis and characterization of novel 2, 2'-bipyrimidine fluorescent derivative for protein binding. | Chemistry Central journal 20110101 |
Protease-associated cellular networks in malaria parasite Plasmodium falciparum. | BMC genomics 20110101 |
Optimisation of 2-cyano-pyrimidine inhibitors of cathepsin K: improving selectivity over hERG. | Bioorganic & medicinal chemistry letters 20101101 |
Mixed azide and 5-(pyrimidyl)tetrazole bridged Co(II)/Mn(II) polymers: synthesis, crystal structures, ferroelectric and magnetic behavior. | Inorganic chemistry 20100920 |
Falcipain inhibitors: optimization studies of the 2-pyrimidinecarbonitrile lead series. | Journal of medicinal chemistry 20100826 |
4-(3-Trifluoromethylphenyl)-pyrimidine-2-carbonitrile as cathepsin S inhibitors: N3, not N1 is critically important. | Bioorganic & medicinal chemistry letters 20100801 |
6-Phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile as cathepsin S inhibitors. | Bioorganic & medicinal chemistry letters 20100801 |
Design and optimization of a series of novel 2-cyano-pyrimidines as cathepsin K inhibitors. | Bioorganic & medicinal chemistry letters 20100301 |
The Diels-Alder-reaction with inverse-electron-demand, a very efficient versatile click-reaction concept for proper ligation of variable molecular partners. | International journal of medical sciences 20100101 |
Gain of a 500-fold sensitivity on an intravital MR contrast agent based on an endohedral gadolinium-cluster-fullerene-conjugate: a new chance in cancer diagnostics. | International journal of medical sciences 20100101 |
A cyclic-RGD-BioShuttle functionalized with TMZ by DARinv 'Click Chemistry' targeted to αvβ3 integrin for therapy. | International journal of medical sciences 20100101 |
Overcoming hERG issues for brain-penetrating cathepsin S inhibitors: 2-cyanopyrimidines. Part 2. | Bioorganic & medicinal chemistry letters 20081001 |
Ensemble-based virtual screening reveals potential novel antiviral compounds for avian influenza neuraminidase. | Journal of medicinal chemistry 20080710 |
Poly[diaqua-μ(2)-oxalato-di-μ(2)-pyrimidine-2-carboxyl-ato-dimanganese(II)]. | Acta crystallographica. Section E, Structure reports online 20080501 |
A manganese(II) coordination polymer with mixed pyrimidine-2-carboxylate and oxalate bridges: synthesis, structure, and magnetism. | Dalton transactions (Cambridge, England : 2003) 20080421 |
Bis(pyrimidine-2-carboxyl-ato-κN,O)copper(II). | Acta crystallographica. Section E, Structure reports online 20080101 |
Pyrimidine-2-carboxamide. | Acta crystallographica. Section E, Structure reports online 20080101 |
1,2-Bis[amino-(pyrimidin-2-yl)methyl-ene]hydrazine dihydrate. | Acta crystallographica. Section E, Structure reports online 20080101 |
Synthesis, X-ray structures and luminescence properties of three multidimensional metal-organic frameworks incorporating the versatile 5-(pyrimidyl)tetrazolato bridging ligand. | Dalton transactions (Cambridge, England : 2003) 20070514 |
Self-assembled cationic heterochiral honeycomb-layered metal complexes with the in situ generated pyrimidine-2-carboxylato bisdidentate ligand. Hydrothermal synthesis, crystal structures, magnetic properties, and theoretical study of [M2(micro-pymca)3]OH.H2O (M = FeII, CoII). | Inorganic chemistry 20070402 |
5-Cyanopyrimidine derivatives as a novel class of potent, selective, and orally active inhibitors of p38alpha MAP kinase. | Journal of medicinal chemistry 20051006 |