Home Aminos Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester

Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester

CAS No.:
140674-76-6
Catalog Number:
AG001COK
Molecular Formula:
C15H15NO4
Molecular Weight:
273.2839
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$97
- +
5mg
≥98%
1 week
United States
$187
- +
10mg
≥98%
1 week
United States
$298
- +
Product Description
Catalog Number:
AG001COK
Chemical Name:
Benzoic acid, 4-[[(2,5-dihydroxyphenyl)methyl]amino]-, methyl ester
CAS Number:
140674-76-6
Molecular Formula:
C15H15NO4
Molecular Weight:
273.2839
MDL Number:
MFCD01074970
IUPAC Name:
methyl 4-[(2,5-dihydroxyphenyl)methylamino]benzoate
InChI:
InChI=1S/C15H15NO4/c1-20-15(19)10-2-4-12(5-3-10)16-9-11-8-13(17)6-7-14(11)18/h2-8,16-18H,9H2,1H3
InChI Key:
QSFREBZMBNRGOK-UHFFFAOYSA-N
SMILES:
COC(=O)c1ccc(cc1)NCc1cc(O)ccc1O
NSC Number:
654705
Properties
Complexity:
315  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
273.1g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
273.288g/mol
Monoisotopic Mass:
273.1g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
78.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.5  
Literature
Title Journal
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Metabolic alterations in K562 cells exposed to taxol and tyrphostin AG957: 1H NMR and biochemical studies. Cell biology international 20051101
The tyrosine kinase inhibitors imatinib and AG957 reverse multidrug resistance in a chronic myelogenous leukemia cell line. Leukemia research 20050701
Synthesis, 11C labeling and biological properties of derivatives of the tyrphostin AG957. Nuclear medicine and biology 20050501
Synthesis, structure-activity relationship, and p210(bcr-abl) protein tyrosine kinase activity of novel AG 957 analogs. Bioorganic & medicinal chemistry 20050301
Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells. Blood 20031215
Inhibition of fast sodium current in rabbit ventricular myocytes by protein tyrosine kinase inhibitors. Pflugers Archiv : European journal of physiology 20030701
Regulation of transient outward current in human atrial myocytes by protein tyrosine kinase pathway. Journal of cardiovascular electrophysiology 20020901
Abnormal growth factor modulation of beta1-integrin-mediated adhesion in chronic myelogenous leukaemia haematopoietic progenitors. British journal of haematology 20011201
Comparison of effects of the tyrosine kinase inhibitors AG957, AG490, and STI571 on BCR-ABL--expressing cells, demonstrating synergy between AG490 and STI571. Blood 20010401
BCR-ABL down-regulates the DNA repair protein DNA-PKcs. Blood 20010401
Properties