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Amg 925

CAS No.:
1401033-86-0
Catalog Number:
AG001C17
Molecular Formula:
C26H29N7O2
Molecular Weight:
471.5542
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$175
- +
10mg
99%
1 week
United States
$223
- +
50mg
99%
1 week
United States
$543
- +
100mg
99%
1 week
United States
$821
- +
Product Description
Catalog Number:
AG001C17
Chemical Name:
Amg 925
CAS Number:
1401033-86-0
Molecular Formula:
C26H29N7O2
Molecular Weight:
471.5542
MDL Number:
MFCD28155269
IUPAC Name:
2-hydroxy-1-[2-[[8-(4-methylcyclohexyl)-4,6,8,11-tetrazatricyclo[7.4.0.02,7]trideca-1(9),2,4,6,10,12-hexaen-5-yl]amino]-7,8-dihydro-5H-1,6-naphthyridin-6-yl]ethanone
InChI:
InChI=1S/C26H29N7O2/c1-16-2-5-18(6-3-16)33-22-13-27-10-8-19(22)20-12-28-26(31-25(20)33)30-23-7-4-17-14-32(24(35)15-34)11-9-21(17)29-23/h4,7-8,10,12-13,16,18,34H,2-3,5-6,9,11,14-15H2,1H3,(H,28,29,30,31)
InChI Key:
BBUVDDPUURMFOX-UHFFFAOYSA-N
SMILES:
OCC(=O)N1CCc2c(C1)ccc(n2)Nc1ncc2c(n1)n([C@@H]1CC[C@H](CC1)C)c1c2ccnc1
UNII:
RB6Y814V4I
Properties
Complexity:
747  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
471.238g/mol
Formal Charge:
0
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
471.565g/mol
Monoisotopic Mass:
471.238g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
109A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.7  
Literature
Title Journal
Preclinical evaluation of AMG 925, a FLT3/CDK4 dual kinase inhibitor for treating acute myeloid leukemia. Molecular cancer therapeutics 20140401
Properties