Home Halogens Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-

Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-

CAS No.:
139667-74-6
Catalog Number:
AG001BH2
Molecular Formula:
C15H24Cl2NO4P
Molecular Weight:
384.2351
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%
1 week
United States
$182
- +
10mg
98%
1 week
United States
$279
- +
25mg
98%
1 week
United States
$557
- +
50mg
98%
1 week
United States
$946
- +
100mg
98%
1 week
United States
$1585
- +
Product Description
Catalog Number:
AG001BH2
Chemical Name:
Phosphinic acid, P-[3-[[(3,4-dichlorophenyl)methyl]amino]propyl]-P-(diethoxymethyl)-
CAS Number:
139667-74-6
Molecular Formula:
C15H24Cl2NO4P
Molecular Weight:
384.2351
MDL Number:
MFCD09878290
IUPAC Name:
3-[(3,4-dichlorophenyl)methylamino]propyl-(diethoxymethyl)phosphinic acid
InChI:
InChI=1S/C15H24Cl2NO4P/c1-3-21-15(22-4-2)23(19,20)9-5-8-18-11-12-6-7-13(16)14(17)10-12/h6-7,10,15,18H,3-5,8-9,11H2,1-2H3,(H,19,20)
InChI Key:
GJZVQXWEIYRHBE-UHFFFAOYSA-N
SMILES:
CCOC(P(=O)(CCCNCc1ccc(c(c1)Cl)Cl)O)OCC
Properties
Complexity:
369  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
383.082g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
384.234g/mol
Monoisotopic Mass:
383.082g/mol
Rotatable Bond Count:
11  
Topological Polar Surface Area:
67.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0
Literature
Title Journal
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The role of protein kinase A in the ethanol-induced increase in spontaneous GABA release onto cerebellar Purkinje neurons. Journal of neurophysiology 20081201
Functional mapping of GABA(B)-receptor subtypes in the thalamus. Journal of neurophysiology 20071201
Understanding your inhibitions: modulation of brain cortical metabolism by GABA(B) receptors. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070801
Differential expression of intrinsic membrane currents in defined cell types of the anterolateral bed nucleus of the stria terminalis. Journal of neurophysiology 20070801
Regulation of synaptic input to hypothalamic presympathetic neurons by GABA(B) receptors. Neuroscience 20061013
Synaptic GABAergic and glutamatergic mechanisms underlying alcohol sensitivity in mouse hippocampal neurons. The Journal of physiology 20060815
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HPLC conditions are critical for the detection of GABA by microdialysis. Journal of neurochemistry 20050801
Discriminative stimulus effects of gamma-hydroxybutyrate (GHB) in rats discriminating GHB from baclofen and diazepam. The Journal of pharmacology and experimental therapeutics 20050701
Comparison of the antinociceptive profiles of gabapentin and 3-methylgabapentin in rat models of acute and persistent pain: implications for mechanism of action. The Journal of pharmacology and experimental therapeutics 20050601
GABA(B) receptor activation modulates GABA(A) receptor-mediated inhibition in chicken nucleus magnocellularis neurons. Journal of neurophysiology 20050301
Differential GABAB Receptor Modulation of Ethanol Effects on GABA(A) synaptic activity in hippocampal CA1 neurons. The Journal of pharmacology and experimental therapeutics 20050301
Modulation of glutamate mobility reveals the mechanism underlying slow-rising AMPAR EPSCs and the diffusion coefficient in the synaptic cleft. Neuron 20040610
Effects of applying gamma-aminobutyric acid(B) drugs into the medial basal hypothalamus on basal luteinizing hormone concentrations and on luteinizing hormone surges in the female sheep. Biology of reproduction 20040201
Blockade of GABA(B) receptors alters the tangential migration of cortical neurons. Cerebral cortex (New York, N.Y. : 1991) 20030901
The ATP-mediated fast current of rat dorsal root ganglion neurons is a novel effector for GABA(B) receptor activation. Neuroscience letters 20030306
Evidence for a GABA(B) receptor component in the spinal action of Substance P (SP) on arterial blood pressure in the awake rat. British journal of pharmacology 20020801
The GABA(B) antagonist CGP 52432 attenuates the stimulatory effect of the GABA(B) agonist SKF 97541 on luteinizing hormone secretion in the male sheep. Experimental biology and medicine (Maywood, N.J.) 20020501
GABA(B) receptor inhibition causes locomotor stimulation in mice. European journal of pharmacology 20011214
A GABA(B) mystery: the search for pharmacologically distinct GABA(B) receptors. Molecular interventions 20011001
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