4-Oxo-1,4-dihydroquinoline-3-carboxylic acid
| Title | Journal |
|---|---|
| Investigations on the 4-quinolone-3-carboxylic acid motif part 5: modulation of the physicochemical profile of a set of potent and selective cannabinoid-2 receptor ligands through a bioisosteric approach. | ChemMedChem 20120501 |
| Nonclassical biological activities of quinolone derivatives. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101 |
| Synthesis and structure-activity relationship of 4-quinolone-3-carboxylic acid based inhibitors of glycogen synthase kinase-3β. | Bioorganic & medicinal chemistry letters 20111001 |
| Investigations on the 4-quinolone-3-carboxylic acid motif. 4. Identification of new potent and selective ligands for the cannabinoid type 2 receptor with diverse substitution patterns and antihyperalgesic effects in mice. | Journal of medicinal chemistry 20110811 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Investigations on the 4-quinolone-3-carboxylic acid motif. 3. Synthesis, structure-affinity relationships, and pharmacological characterization of 6-substituted 4-quinolone-3-carboxamides as highly selective cannabinoid-2 receptor ligands. | Journal of medicinal chemistry 20100826 |
| Tautomerism and magnesium chelation of HIV-1 integrase inhibitors: a theoretical study. | ChemMedChem 20100705 |
| Dichloro-4-quinolinol-3-carboxylic acid: synthesis and antioxidant abilities to scavenge radicals and to protect methyl linoleate and DNA. | European journal of medicinal chemistry 20100501 |
| Ethyl 4-(3-hydroxy-phen-yl)-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexa-hydro-quinoline-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20091101 |
| The 4-quinolone-3-carboxylic acid motif as a multivalent scaffold in medicinal chemistry. | Current medicinal chemistry 20090101 |
| Heterocycles [h]-fused onto 4-oxoquinoline-3-carboxylic acid, part VIII [1]. Convenient synthesis and antimicrobial properties of substituted hexahydro[1,4]diazepino[2,3-h]quinoline-9-carboxylic acid and its tetrahydroquino[7,8-b]benzodiazepine analog. | Molecules (Basel, Switzerland) 20081118 |
| Investigations on the 4-quinolone-3-carboxylic acid motif. 1. Synthesis and structure-activity relationship of a class of human immunodeficiency virus type 1 integrase inhibitors. | Journal of medicinal chemistry 20080828 |
| Investigations on the 4-quinolone-3-carboxylic acid motif. 2. Synthesis and structure-activity relationship of potent and selective cannabinoid-2 receptor agonists endowed with analgesic activity in vivo. | Journal of medicinal chemistry 20080828 |
| Affinity of 3-acyl substituted 4-quinolones at the benzodiazepine site of GABA(A) receptors. | Bioorganic & medicinal chemistry 20080715 |
| Heterocycles [h]fused onto 4-oxoquinoline-3-carboxylic acid, part IV. Convenient synthesis of substituted hexahydro [1,4]thiazepino[2,3-h]quinoline-9-carboxylic acid and its tetrahydroquino[7,8-b]benzothiazepine homolog. | Molecules (Basel, Switzerland) 20070727 |
| Evaluation of 3-carboxy-4(1H)-quinolones as inhibitors of human protein kinase CK2. | Journal of medicinal chemistry 20061102 |
| Synthesis and antibacterial activity of the 4-quinolone-3-carboxylic acid derivatives having a trifluoromethyl group as a novel N-1 substituent. | Journal of medicinal chemistry 20050505 |