sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks Lemborexant

Lemborexant

CAS No.:
1369764-02-2
Catalog Number:
AG0012M9
Molecular Formula:
C22H20F2N4O2
Molecular Weight:
410.4166
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$640
- +
10mg
99%
1 week
United States
$890
- +
50mg
99%
1 week
United States
$2557
- +
Product Description
Catalog Number:
AG0012M9
Chemical Name:
Lemborexant
CAS Number:
1369764-02-2
Molecular Formula:
C22H20F2N4O2
Molecular Weight:
410.4166
MDL Number:
MFCD28502271
IUPAC Name:
(1R,2S)-2-[(2,4-dimethylpyrimidin-5-yl)oxymethyl]-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl)cyclopropane-1-carboxamide
InChI:
InChI=1S/C22H20F2N4O2/c1-13-19(11-25-14(2)27-13)30-12-22(15-4-3-5-16(23)8-15)9-18(22)21(29)28-20-7-6-17(24)10-26-20/h3-8,10-11,18H,9,12H2,1-2H3,(H,26,28,29)/t18-,22+/m0/s1
InChI Key:
MUGXRYIUWFITCP-PGRDOPGGSA-N
SMILES:
O=C([C@@H]1C[C@@]1(COc1cnc(nc1C)C)c1cccc(c1)F)Nc1ccc(cn1)F
UNII:
0K5743G68X
Properties
Complexity:
612  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
410.155g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
410.425g/mol
Monoisotopic Mass:
410.155g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
77A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.2  
Literature
Title Journal
Discovery of (1R,2S)-2-{[(2,4-Dimethylpyrimidin-5-yl)oxy]methyl}-2-(3-fluorophenyl)-N-(5-fluoropyridin-2-yl)cyclopropanecarboxamide (E2006): A Potent and Efficacious Oral Orexin Receptor Antagonist. Journal of medicinal chemistry 20150611
Properties