Home Halogens 2-Propanol, 1,3-dichloro-, 2,2',2''-phosphate

2-Propanol, 1,3-dichloro-, 2,2',2''-phosphate

CAS No.:
13674-87-8
Catalog Number:
AG0012B0
Molecular Formula:
C9H15Cl6O4P
Molecular Weight:
430.9048
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
97%(HPLC)
In Stock USA
United States
$44
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25g
97%(HPLC)
In Stock USA
United States
$72
- +
100g
97%(HPLC)
In Stock USA
United States
$110
- +
500g
97%(HPLC)
In Stock USA
United States
$210
- +
Product Description
Catalog Number:
AG0012B0
Chemical Name:
2-Propanol, 1,3-dichloro-, 2,2',2''-phosphate
CAS Number:
13674-87-8
Molecular Formula:
C9H15Cl6O4P
Molecular Weight:
430.9048
MDL Number:
MFCD00083121
IUPAC Name:
tris(1,3-dichloropropan-2-yl) phosphate
InChI:
InChI=1S/C9H15Cl6O4P/c10-1-7(2-11)17-20(16,18-8(3-12)4-13)19-9(5-14)6-15/h7-9H,1-6H2
InChI Key:
ASLWPAWFJZFCKF-UHFFFAOYSA-N
SMILES:
ClCC(OP(=O)(OC(CCl)CCl)OC(CCl)CCl)CCl
EC Number:
237-159-2
UNII:
B1PRV4G0T0
Properties
Complexity:
243  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
429.881g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
430.889g/mol
Monoisotopic Mass:
427.884g/mol
Rotatable Bond Count:
12  
Topological Polar Surface Area:
44.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.3  
Literature
Title Journal
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Organophosphate Flame-Retardants Alter Adult Mouse Homeostasis and Gene Expression in a Sex-Dependent Manner Potentially Through Interactions With ERα. Toxicological sciences : an official journal of the Society of Toxicology 20180301
Tris (1,3-dichloro-2-propyl) phosphate induces toxicity by stimulating CaMK2 in PC12 cells. Environmental toxicology 20170601
Parental transfer of tris(1,3-dichloro-2-propyl) phosphate and transgenerational inhibition of growth of zebrafish exposed to environmentally relevant concentrations. Environmental pollution (Barking, Essex : 1987) 20170101
Tris (1,3-dichloro-2-propyl) phosphate-induced apoptotic signaling pathways in SH-SY5Y neuroblastoma cells. Neurotoxicology 20170101
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The Flame-Retardant Tris(1,3-dichloro-2-propyl) Phosphate Represses Androgen Signaling in Human Prostate Cancer Cell Lines. Journal of biochemical and molecular toxicology 20160501
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Acute Exposure to Tris(1,3-dichloro-2-propyl) Phosphate (TDCIPP) Causes Hepatic Inflammation and Leads to Hepatotoxicity in Zebrafish. Scientific reports 20160101
Environmentally Relevant Concentrations of the Flame Retardant Tris(1,3-dichloro-2-propyl) Phosphate Inhibit Growth of Female Zebrafish and Decrease Fecundity. Environmental science & technology 20151215
Bioconcentration and transfer of the organophorous flame retardant 1,3-dichloro-2-propyl phosphate causes thyroid endocrine disruption and developmental neurotoxicity in zebrafish larvae. Environmental science & technology 20150421
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Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects. International journal of molecular sciences 20150101
Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and tris(2-chloro-2-ethyl)phosphate (TCEP). Neurotoxicology and teratology 20150101
Developmental exposure to organophosphate flame retardants elicits overt toxicity and alters behavior in early life stage zebrafish (Danio rerio). Toxicological sciences : an official journal of the Society of Toxicology 20141201
Time-dependent effects of the flame retardant tris(1,3-dichloro-2-propyl) phosphate (TDCPP) on mRNA expression, in vitro and in ovo, reveal optimal sampling times for rapidly metabolized compounds. Environmental toxicology and chemistry 20141201
Potential estrogenic effects of phosphorus-containing flame retardants. Environmental science & technology 20140617
Toxicity of TDCPP and TCEP on PC12 cell: changes in CAMKII, GAP43, tubulin and NF-H gene and protein levels. Toxicology letters 20140616
Multiple bio-analytical methods to reveal possible molecular mechanisms of developmental toxicity in zebrafish embryos/larvae exposed to tris(2-butoxyethyl) phosphate. Aquatic toxicology (Amsterdam, Netherlands) 20140501
Use of an avian hepatocyte assay and the avian Toxchip Polymerse chain reaction array for testing prioritization of 16 organic flame retardants. Environmental toxicology and chemistry 20140301
Tris(1,3-dichloro-2-propyl) phosphate perturbs the expression of genes involved in immune response and lipid and steroid metabolism in chicken embryos. Toxicology and applied pharmacology 20140301
In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors. Toxicology 20131206
Toxicogenomic responses of zebrafish embryos/larvae to tris(1,3-dichloro-2-propyl) phosphate (TDCPP) reveal possible molecular mechanisms of developmental toxicity. Environmental science & technology 20130917
In Ovo effects of two organophosphate flame retardants--TCPP and TDCPP--on pipping success, development, mRNA expression, and thyroid hormone levels in chicken embryos. Toxicological sciences : an official journal of the Society of Toxicology 20130701
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Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays. Environmental science & technology 20130319
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Concentrations of organophosphate esters and brominated flame retardants in German indoor dust samples. Journal of environmental monitoring : JEM 20120901
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Levels and distributions of organophosphate flame retardants and plasticizers in sediment from Taihu Lake, China. Environmental toxicology and chemistry 20120701
Indoor air in schools and lung function of Austrian school children. Journal of environmental monitoring : JEM 20120701
Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish. Aquatic toxicology (Amsterdam, Netherlands) 20120615
Effects of tris(1,3-dichloro-2-propyl) phosphate and tris(1-chloropropyl) phosphate on cytotoxicity and mRNA expression in primary cultures of avian hepatocytes and neuronal cells. Toxicological sciences : an official journal of the Society of Toxicology 20120301
Complete detoxification of tris(1,3-dichloro-2-propyl) phosphate by mixed two bacteria, Sphingobium sp. strain TCM1 and Arthrobacter sp. strain PY1. Journal of bioscience and bioengineering 20120101
Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells. Toxicology and applied pharmacology 20111101
Brominated and organophosphate flame retardants in selected consumer products on the Japanese market in 2008. Journal of hazardous materials 20110915
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Properties