Go 6983
| Title | Journal |
|---|---|
| 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure influence the expression of glutamate transporter GLT-1 in C6 glioma cells via the Ca(2+) /protein kinase C pathway. | Journal of applied toxicology : JAT 20161101 |
| p300/β-Catenin Interactions Regulate Adult Progenitor Cell Differentiation Downstream of WNT5a/Protein Kinase C (PKC). | The Journal of biological chemistry 20160318 |
| Flavanoids induce expression of the suppressor of cytokine signalling 3 (SOCS3) gene and suppress IL-6-activated signal transducer and activator of transcription 3 (STAT3) activation in vascular endothelial cells. | The Biochemical journal 20130901 |
| A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. | The Biochemical journal 20130415 |
| Antidepressants inhibit DNA methyltransferase 1 through reducing G9a levels. | The Biochemical journal 20121115 |
| Novel regulation of protein kinase C-η. | Biochemical and biophysical research communications 20120907 |
| Phorbol ester-modulation of estrogenic genomic effects triggered by the environmental contaminant benzanthracene. | Toxicology in vitro : an international journal published in association with BIBRA 20120901 |
| Constriction of retinal arterioles to endothelin-1: requisite role of rho kinase independent of protein kinase C and L-type calcium channels. | Investigative ophthalmology & visual science 20120501 |
| Interferon-γ-induced PD-L1 surface expression on human oral squamous carcinoma via PKD2 signal pathway. | Immunobiology 20120401 |
| Regulation and rate limiting mechanisms of Ca2+ ATPase (SERCA2) expression in cardiac myocytes. | Molecular and cellular biochemistry 20120201 |
| The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner. | Cellular signalling 20120101 |
| Functional interactions between the oxytocin receptor and the β2-adrenergic receptor: implications for ERK1/2 activation in human myometrial cells. | Cellular signalling 20120101 |
| Reduced calcium current density in female versus male mouse adrenal chromaffin cells in situ. | Cell calcium 20120101 |
| Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. | Nature biotechnology 20111101 |
| Inhibition of protein kinase C promotes differentiation of neuroblastoma × glioma NG108-15 hybrid cells. | The European journal of neuroscience 20111001 |
| Protective effect of 4,4'-diaminodiphenylsulfone against paraquat-induced mouse lung injury. | Experimental & molecular medicine 20110930 |
| Protein kinase C epsilon affects mitochondrial function through estrogen-related receptor alpha. | Cellular signalling 20110901 |
| Dual function of protein kinase C (PKC) in 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced manganese superoxide dismutase (MnSOD) expression: activation of CREB and FOXO3a by PKC-alpha phosphorylation and by PKC-mediated inactivation of Akt, respectively. | The Journal of biological chemistry 20110826 |
| Protein kinase D regulates the adiponectin gene expression through phosphorylation of AP-2: a common pathway to the ABCA1 gene regulation. | Atherosclerosis 20110501 |
| Proteomic analysis of cPKCβII-interacting proteins involved in HPC-induced neuroprotection against cerebral ischemia of mice. | Journal of neurochemistry 20110401 |
| PKC inhibitors RO 31-8220 and Gö 6983 enhance epinephrine-induced platelet aggregation in catecholamine hypo-responsive platelets by enhancing Akt phosphorylation. | BMB reports 20110201 |
| Differential roles of phosphorylated AMPA receptor GluR1 subunits at Serine-831 and Serine-845 sites in spinal cord dorsal horn in a rat model of post-operative pain. | Neurochemical research 20110101 |
| Nucleotide oligomerization domain 1 is a dominant pathway for NOS2 induction in vascular smooth muscle cells: comparison with Toll-like receptor 4 responses in macrophages. | British journal of pharmacology 20100801 |
| Rapid activation of dormant presynaptic terminals by phorbol esters. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100728 |
| SSeCKS promote beta-amyloid-induced PC12 cells neurotoxicity by up-regulating tau phosphorylation in Alzheimer's disease. | Molecular and cellular biochemistry 20100701 |
| Phorbol ester phorbol-12-myristate-13-acetate induces epithelial to mesenchymal transition in human prostate cancer ARCaPE cells. | The Prostate 20100701 |
| [Effect of PKC signalling pathway and aldose reductase on expression of fibronectin induced by transforming growth factor-β1 in human mesangial cells]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20100601 |
| Regulation of protein kinase C delta downregulation by protein kinase C epsilon and mammalian target of rapamycin complex 2. | Cellular signalling 20091101 |
| Anti-cancer activity and mechanistic features of a NK cell activating molecule. | Cancer immunology, immunotherapy : CII 20091001 |
| Establishment of screening system toward discovery of kinase inhibitors using label-free on-chip phosphorylation assays. | Bio Systems 20090901 |
| Involvement of protein kinase C in IL-1beta-induced expression of cyclooxygenase-2 in human gingival fibroblasts. | Journal of oral science 20090901 |
| Knockout of the predominant conventional PKC isoform, PKCalpha, in mouse skeletal muscle does not affect contraction-stimulated glucose uptake. | American journal of physiology. Endocrinology and metabolism 20090801 |
| Cortical F-actin, the exocytic mode, and neuropeptide release in mouse chromaffin cells is regulated by myristoylated alanine-rich C-kinase substrate and myosin II. | Molecular biology of the cell 20090701 |
| Low-power laser irradiation promotes cell proliferation by activating PI3K/Akt pathway. | Journal of cellular physiology 20090601 |
| Protein kinase D mediates mitogenic signaling by Gq-coupled receptors through protein kinase C-independent regulation of activation loop Ser744 and Ser748 phosphorylation. | The Journal of biological chemistry 20090515 |
| Role of cPKCalpha and nPKCepsilon in EGF-stimulated goblet cell proliferation. | Investigative ophthalmology & visual science 20090201 |
| Phosphatidylethanol mediates its effects on the vascular endothelial growth factor via HDL receptor in endothelial cells. | Alcoholism, clinical and experimental research 20090201 |
| Induction of COX-2 in human airway cells by manganese: role of PI3K/PKB, p38 MAPK, PKCs, Src, and glutathione depletion. | Toxicology in vitro : an international journal published in association with BIBRA 20090201 |
| Leptin stimulated C-reactive protein production by human coronary artery endothelial cells. | Journal of vascular research 20090101 |
| Low-power laser irradiation activates Src tyrosine kinase through reactive oxygen species-mediated signaling pathway. | Journal of cellular physiology 20081101 |
| PKC alpha protein but not kinase activity is critical for glioma cell proliferation and survival. | International journal of cancer 20080815 |
| Phorbol ester-stimulated NF-kappaB-dependent transcription: roles for isoforms of novel protein kinase C. | Cellular signalling 20080701 |
| Inhibitory effect of xanthones isolated from the pericarp of Garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation. | Bioorganic & medicinal chemistry 20080415 |
| Protein kinase C inhibitors alter neurotensin receptor binding and function in prostate cancer PC3 cells. | Regulatory peptides 20080410 |
| Foreign body-type multinucleated giant cell formation requires protein kinase C beta, delta, and zeta. | Experimental and molecular pathology 20080201 |
| nPKCepsilon, a P2Y2-R downstream effector in regulated mucin secretion from airway goblet cells. | American journal of physiology. Cell physiology 20071101 |
| Effect of phorbol ester and platelet-derived growth factor on protein kinase C in rat hepatic stellate cells. | Liver international : official journal of the International Association for the Study of the Liver 20071001 |
| Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C. | American journal of physiology. Lung cellular and molecular physiology 20070801 |
| Protein kinase D interaction with TLR5 is required for inflammatory signaling in response to bacterial flagellin. | Journal of immunology (Baltimore, Md. : 1950) 20070501 |
| Regulation of anion exchanger Slc26a6 by protein kinase C. | American journal of physiology. Cell physiology 20070401 |
| Sustained phosphorylation of tyrosine hydroxylase at serine 40: a novel mechanism for maintenance of catecholamine synthesis. | Journal of neurochemistry 20070101 |
| Beta(2)-Adrenergic activation increases glycogen synthesis in L6 skeletal muscle cells through a signalling pathway independent of cyclic AMP. | Diabetologia 20070101 |
| Lactoferrin stimulates erythrocyte Na+/K+ -adenosine triphosphatase: effect of some modulators of membrane phosphorylation. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101 |
| Curcumin inhibits neurotensin-mediated interleukin-8 production and migration of HCT116 human colon cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060915 |
| Angiotensin II promotes the proliferation of activated pancreatic stellate cells by Smad7 induction through a protein kinase C pathway. | Biochemical and biophysical research communications 20060217 |
| Effect of topiramate and dBcAMP on expression of the glutamate transporters GLAST and GLT-1 in astrocytes cultured separately, or together with neurons. | Neurochemistry international 20060101 |
| Effect of PKC isozyme inhibition on forskolin-induced activation of BKCa channels in rat pulmonary arterial smooth muscle. | Lung 20060101 |
| Mu and kappa opioid receptors activate ERK/MAPK via different protein kinase C isoforms and secondary messengers in astrocytes. | The Journal of biological chemistry 20050729 |
| Protein kinase D specifically mediates apoptosis signal-regulating kinase 1-JNK signaling induced by H2O2 but not tumor necrosis factor. | The Journal of biological chemistry 20050513 |
| Protein kinase C modulates agonist-sensitive release of Ca2+ from internal stores in HEK293 cells overexpressing the calcium sensing receptor. | The Journal of biological chemistry 20050211 |
| Inhibition of L-type Cav1.2 Ca2+ channels by 2,(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002) and 2-[1-(3-dimethyl-aminopropyl)-5-methoxyindol-3-yl]-3-(1H-indol-3-yl) maleimide (Go6983). | Molecular pharmacology 20050201 |
| alpha1A-adrenoceptors activate glucose uptake in L6 muscle cells through a phospholipase C-, phosphatidylinositol-3 kinase-, and atypical protein kinase C-dependent pathway. | Endocrinology 20050201 |
| Metabolic arrest and its regulation in anoxic eel hepatocytes. | Physiological and biochemical zoology : PBZ 20050101 |
| Gö 6983: a fast acting protein kinase C inhibitor that attenuates myocardial ischemia/reperfusion injury. | Cardiovascular drug reviews 20050101 |
| A novel Ca2+-independent signaling pathway to extracellular signal-regulated protein kinase by coactivation of NMDA receptors and metabotropic glutamate receptor 5 in neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201 |
| IL-10 production induced by HIV-1 Tat stimulation of human monocytes is dependent on the activation of PKC beta(II) and delta isozymes. | Microbes and infection 20041101 |
| Possible involvement of protein kinase C activation in differentiation of human umbilical vein endothelium-derived cell into smooth muscle-like cell. | Biology of the cell 20040901 |
| Inhibition of Ca2+-dependent PKC isoforms unmasks ERK-dependent hypertrophic growth evoked by phenylephrine in adult ventricular cardiomyocytes. | Cardiovascular research 20040815 |
| Receptor activator of nuclear factor-kappaB is induced by a rottlerin-sensitive and p38 MAP kinase-dependent pathway during monocyte differentiation. | Molecules and cells 20040630 |
| PfPKB, a novel protein kinase B-like enzyme from Plasmodium falciparum: I. Identification, characterization, and possible role in parasite development. | The Journal of biological chemistry 20040604 |
| PKC and PKA inhibitors reverse tolerance to morphine-induced hypothermia and supraspinal analgesia in mice. | European journal of pharmacology 20040525 |
| Mechanism of human urotensin II-induced contraction in rat aorta. | Journal of pharmacological sciences 20040401 |
| PKA- and PKC-dependent regulation of angiopoietin 2 mRNA in human granulosa lutein cells. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040201 |
| Extracellular signal-regulated kinase 1/2 is required for the induction of group I metabotropic glutamate receptor-mediated epileptiform discharges. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040107 |
| Protein kinase C modulation of cyclic GMP in rat neonatal pulmonary vascular smooth muscle. | Lung 20040101 |
| Possible role of the protein kinase C/CPI-17 pathway in the augmented contraction of human myometrium after gestation. | British journal of pharmacology 20031201 |
| Pathways of induction of peroxiredoxin I expression in osteoblasts: roles of p38 mitogen-activated protein kinase and protein kinase C. | The Journal of biological chemistry 20020405 |
| Inhibition of protein kinase C mu by various inhibitors. Differentiation from protein kinase c isoenzymes. | FEBS letters 19960826 |