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Home Nitros Guanosine, 6-S-[(4-nitrophenyl)methyl]-6-thio-

Guanosine, 6-S-[(4-nitrophenyl)methyl]-6-thio-

CAS No.:
13153-27-0
Catalog Number:
AG000ZCT
Molecular Formula:
C17H18N6O6S
Molecular Weight:
434.4264
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
99%
1 week
United States
$279
- +
5mg
99%
1 week
United States
$543
- +
Product Description
Catalog Number:
AG000ZCT
Chemical Name:
Guanosine, 6-S-[(4-nitrophenyl)methyl]-6-thio-
CAS Number:
13153-27-0
Molecular Formula:
C17H18N6O6S
Molecular Weight:
434.4264
MDL Number:
MFCD00005737
IUPAC Name:
(2R,3R,4S,5R)-2-[2-amino-6-[(4-nitrophenyl)methylsulfanyl]purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
InChI:
InChI=1S/C17H18N6O6S/c18-17-20-14-11(19-7-22(14)16-13(26)12(25)10(5-24)29-16)15(21-17)30-6-8-1-3-9(4-2-8)23(27)28/h1-4,7,10,12-13,16,24-26H,5-6H2,(H2,18,20,21)/t10-,12-,13-,16-/m1/s1
InChI Key:
BRSNNJIJEZWSBU-XNIJJKJLSA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1nc(N)nc2SCc1ccc(cc1)[N+](=O)[O-]
Properties
Complexity:
608  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
434.101g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
434.427g/mol
Monoisotopic Mass:
434.101g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
211A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.1  
Literature
Title Journal
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorganic & medicinal chemistry 20080401
Novel C2-purine position analogs of nitrobenzylmercaptopurine riboside as human equilibrative nucleoside transporter 1 inhibitors. Bioorganic & medicinal chemistry 20071215
Indirect activation of adenosine A1 receptors in cultured rat hippocampal neurons by volatile anaesthetics. European journal of anaesthesiology 20050901
Uptake and release of [3H]adenosine in human dental pulp. Archives of oral biology 20030401
Activation of A(3) receptors by endogenous adenosine inhibits synaptic transmission during hypoxia in rat cortical neurons. Restorative neurology and neuroscience 20030101
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Purine nucleoside-dependent inhibition of cellular proliferation in 1321N1 human astrocytoma cells. The Journal of pharmacology and experimental therapeutics 20011101
Properties