Home Other Building Blocks Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)-

Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)-

CAS No.:
129453-61-8
Catalog Number:
AG000Z4U
Molecular Formula:
C32H47F5O3S
Molecular Weight:
606.7708
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%(HPLC)
In Stock USA
United States
$87
- +
25mg
98%(HPLC)
In Stock USA
United States
$150
- +
100mg
98%(HPLC)
In Stock USA
United States
$521
- +
Product Description
Catalog Number:
AG000Z4U
Chemical Name:
Estra-1,3,5(10)-triene-3,17-diol, 7-[9-[(4,4,5,5,5-pentafluoropentyl)sulfinyl]nonyl]-, (7α,17β)-
CAS Number:
129453-61-8
Molecular Formula:
C32H47F5O3S
Molecular Weight:
606.7708
MDL Number:
MFCD00903953
IUPAC Name:
(7R,8R,9S,13S,14S,17S)-13-methyl-7-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)nonyl]-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthrene-3,17-diol
InChI:
InChI=1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1
InChI Key:
VWUXBMIQPBEWFH-WCCTWKNTSA-N
SMILES:
O=S(CCCC(C(F)(F)F)(F)F)CCCCCCCCC[C@@H]1Cc2cc(O)ccc2[C@@H]2[C@@H]1[C@@H]1CC[C@@H]([C@]1(CC2)C)O
NSC Number:
719276
Properties
Complexity:
854  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
0
Exact Mass:
606.317g/mol
Formal Charge:
0
Heavy Atom Count:
41  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
606.777g/mol
Monoisotopic Mass:
606.317g/mol
Rotatable Bond Count:
14  
Topological Polar Surface Area:
76.7A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
9.2  
Literature
Title Journal
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Several synthetic progestins disrupt the glial cell specific-brain aromatase expression in developing zebra fish. Toxicology and applied pharmacology 20160815
Inhibition of Macrophage CD36 Expression and Cellular Oxidized Low Density Lipoprotein (oxLDL) Accumulation by Tamoxifen: A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)γ-DEPENDENT MECHANISM. The Journal of biological chemistry 20160812
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Bisphenol A, an environmental estrogen-like toxic chemical, induces cardiac fibrosis by activating the ERK1/2 pathway. Toxicology letters 20160527
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Icam5 Expression Exhibits Sex Differences in the Neonatal Pituitary and Is Regulated by Estradiol and Bisphenol A. Endocrinology 20160401
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Dioscin promotes osteoblastic proliferation and differentiation via Lrp5 and ER pathway in mouse and human osteoblast-like cell lines. Journal of biomedical science 20140101
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Endocrine disrupting chemicals promote the growth of ovarian cancer cells via the ER-CXCL12-CXCR4 signaling axis. Molecular carcinogenesis 20130901
Dichlorodiphenyltrichloroethane technical mixture regulates cell cycle and apoptosis genes through the activation of CAR and ERα in mouse livers. Toxicology and applied pharmacology 20130901
Resveratrol regulates the cell viability promoted by 17β-estradiol or bisphenol A via down-regulation of the cross-talk between estrogen receptor α and insulin growth factor-1 receptor in BG-1 ovarian cancer cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130901
An in vitro investigation of endocrine disrupting effects of the mycotoxin alternariol. Toxicology and applied pharmacology 20130815
Neonatal exposure to zearalenone induces long term modulation of ABC transporter expression in testis. Toxicology 20130809
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Danshen mediates through estrogen receptors to activate Akt and inhibit apoptosis effect of Leu27IGF-II-induced IGF-II receptor signaling activation in cardiomyoblasts. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130601
Exposure to bisphenol A disrupts meiotic progression during spermatogenesis in adult rats through estrogen-like activity. Cell death & disease 20130601
Bisphenol A affects androgen receptor function via multiple mechanisms. Chemico-biological interactions 20130525
Differential action of monohydroxylated polycyclic aromatic hydrocarbons with estrogen receptors α and β. Toxicological sciences : an official journal of the Society of Toxicology 20130401
Notoginsenoside R1 attenuates cardiac dysfunction in endotoxemic mice: an insight into oestrogen receptor activation and PI3K/Akt signalling. British journal of pharmacology 20130401
The effect of triclosan on the uterotrophic response to extended doses of ethinyl estradiol in the weanling rat. Reproductive toxicology (Elmsford, N.Y.) 20130401
The natural estrogenic compound diarylheptanoid (D3): in vitro mechanisms of action and in vivo uterine responses via estrogen receptor α. Environmental health perspectives 20130401
Benzophenone-1 stimulated the growth of BG-1 ovarian cancer cells by cell cycle regulation via an estrogen receptor alpha-mediated signaling pathway in cellular and xenograft mouse models. Toxicology 20130308
4-tert-Octylphenol stimulates the expression of cathepsins in human breast cancer cells and xenografted breast tumors of a mouse model via an estrogen receptor-mediated signaling pathway. Toxicology 20130208
Bisphenol A interferes with thyroid specific gene expression. Toxicology 20130208
Interactions of pharmaceuticals and other xenobiotics on key detoxification mechanisms and cytoskeleton in Poeciliopsis lucida hepatocellular carcinoma, PLHC-1 cell line. Toxicology in vitro : an international journal published in association with BIBRA 20130201
Endocrine disruptors fludioxonil and fenhexamid stimulate miR-21 expression in breast cancer cells. Toxicological sciences : an official journal of the Society of Toxicology 20130101
Estradiol antagonism of glucocorticoid-induced GILZ expression in human uterine epithelial cells and murine uterus. Endocrinology 20130101
[Effects of naringin on proliferation, differentiation and maturation of rat calvarial osteoblasts in vitro]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20130101
Long-term treatment with san'o-shashin-to, a kampo medicine, markedly ameliorates cardiac ischemia-reperfusion injury in ovariectomized rats via the redox-dependent mechanism. Circulation journal : official journal of the Japanese Circulation Society 20130101
Environmental alkylphenols modulate cytokine expression in plasmacytoid dendritic cells. PloS one 20130101
Assessment of cellular estrogenic activity based on estrogen receptor-mediated reduction of soluble-form catechol-O-methyltransferase (COMT) expression in an ELISA-based system. PloS one 20130101
Cadmium mimics estrogen-driven cell proliferation and prolactin secretion from anterior pituitary cells. PloS one 20130101
Transactivating function (AF) 2-mediated AF-1 activity of estrogen receptor α is crucial to maintain male reproductive tract function. Proceedings of the National Academy of Sciences of the United States of America 20121218
Herba epimedii flavonoids suppress osteoclastic differentiation and bone resorption by inducing G2/M arrest and apoptosis. Biochimie 20121201
Potent vasodilation effect of amurensin G is mediated through the phosphorylation of endothelial nitric oxide synthase. Biochemical pharmacology 20121201
Estrogenic effects of fusarielins in human breast cancer cell lines. Toxicology letters 20121115
Estrogen receptor potentiates mTORC2 signaling in breast cancer cells by upregulating superoxide anions. Free radical biology & medicine 20121115
Prevention of tobacco carcinogen-induced lung cancer in female mice using antiestrogens. Carcinogenesis 20121101
Calbindin-D9k as a sensitive molecular biomarker for evaluating the synergistic impact of estrogenic chemicals on GH3 rat pituitary cells. International journal of molecular medicine 20121101
Carboplatin treatment of antiestrogen-resistant breast cancer cells. International journal of oncology 20121101
Epigallocatechin gallate affects survival and metabolism of human sperm. Molecular nutrition & food research 20121101
Prostaglandin E2 stimulates estradiol synthesis in the cerebellum postnatally with associated effects on Purkinje neuron dendritic arbor and electrophysiological properties. Endocrinology 20121101
Fulvestrant 500 mg versus anastrozole 1 mg for the first-line treatment of advanced breast cancer: follow-up analysis from the randomized 'FIRST' study. Breast cancer research and treatment 20121101
Long-term treatment with the pure anti-estrogen fulvestrant durably remodels estrogen signaling in BG-1 ovarian cancer cells. The Journal of steroid biochemistry and molecular biology 20121001
Breast cancer: Anastrozole and fulvestrant--combination to unlock efficacy. Nature reviews. Clinical oncology 20121001
Additional effects of bisphenol A and paraben on the induction of calbindin-D(9K) and progesterone receptor via an estrogen receptor pathway in rat pituitary GH3 cells. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20121001
Ovarian function suppression and fulvestrant as endocrine therapy in premenopausal women with metastatic breast cancer. European journal of cancer (Oxford, England : 1990) 20120901
Effects of 17β-estradiol on adiponectin regulation of the expression of osteoprotegerin and receptor activator of nuclear factor-κB ligand. Bone 20120901
Phorbol ester-modulation of estrogenic genomic effects triggered by the environmental contaminant benzanthracene. Toxicology in vitro : an international journal published in association with BIBRA 20120901
Cellular actions of testosterone in vascular cells: mechanism independent of aromatization to estradiol. Steroids 20120901
Effects of bisphenol A on the proliferation and cell cycle of HBL-100 cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
Oral metronomic cyclophosphamide and methotrexate plus fulvestrant in advanced breast cancer patients: a mono-institutional case-cohort report. The breast journal 20120901
Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity. Toxicology 20120816
The endocrine disruptor diethylstilbestrol induces adipocyte differentiation and promotes obesity in mice. Toxicology and applied pharmacology 20120815
Combination anastrozole and fulvestrant in metastatic breast cancer. The New England journal of medicine 20120802
Interplay of estrogen receptors and GPR30 for the regulation of early membrane initiated transcriptional effects: A pharmacological approach. Steroids 20120801
Estrogen suppresses expression of the matrix metalloproteinase inhibitor reversion-inducing cysteine-rich protein with Kazal motifs (RECK) within the mouse uterus. Endocrine 20120801
Estrogen receptor α attenuates therapeutic efficacy of paclitaxel on breast xenograft tumors. Breast cancer research and treatment 20120801
Early membrane initiated transcriptional effects of estrogens in breast cancer cells: First pharmacological evidence for a novel membrane estrogen receptor element (ERx). Steroids 20120801
NFκB signaling is important for growth of antiestrogen resistant breast cancer cells. Breast cancer research and treatment 20120801
Phthalates stimulate the epithelial to mesenchymal transition through an HDAC6-dependent mechanism in human breast epithelial stem cells. Toxicological sciences : an official journal of the Society of Toxicology 20120801
Estrogenic/antiestrogenic activities of a Epimedium koreanum extract and its major components: in vitro and in vivo studies. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801
Preliminary experience with personalized and targeted therapy for pediatric brain tumors. Pediatric blood & cancer 20120715
Neonatal phytoestrogen exposure alters oviduct mucosal immune response to pregnancy and affects preimplantation embryo development in the mouse. Biology of reproduction 20120701
Combine therapy of gefitinib and fulvestrant enhances antitumor effects on NSCLC cell lines with acquired resistance to gefitinib. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120701
Intrahypothalamic estradiol modulates hypothalamus-pituitary-adrenal-axis activity in female rats. Endocrinology 20120701
17-Alpha-estradiol ameliorating oxygen-induced retinopathy in a murine model. Japanese journal of ophthalmology 20120701
Small-animal PET of steroid hormone receptors predicts tumor response to endocrine therapy using a preclinical model of breast cancer. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20120701
Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland. Breast cancer research and treatment 20120701
AKT-aro and HER2-aro, models for de novo resistance to aromatase inhibitors; molecular characterization and inhibitor response studies. Breast cancer research and treatment 20120701
Mechanisms of FGFR3 actions in endocrine resistant breast cancer. International journal of cancer 20120615
Wnt family genes and their modulation in the ovary-independent and persistent vaginal epithelial cell proliferation and keratinization induced by neonatal diethylstilbestrol exposure in mice. Toxicology 20120614
FACT: an open-label randomized phase III study of fulvestrant and anastrozole in combination compared with anastrozole alone as first-line therapy for patients with receptor-positive postmenopausal breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120601
A randomized trial of combination anastrozole plus gefitinib and of combination fulvestrant plus gefitinib in the treatment of postmenopausal women with hormone receptor positive metastatic breast cancer. Breast cancer research and treatment 20120601
Polyendocrine treatment in estrogen receptor-positive breast cancer: a 'FACT' yet to be proven. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120601
17β-Estradiol prevents cell death and mitochondrial dysfunction by an estrogen receptor-dependent mechanism in astrocytes after oxygen-glucose deprivation/reperfusion. Free radical biology & medicine 20120601
Differential expression and regulation of angiopoietin-3 in mouse uterus during preimplantation period. Journal of experimental zoology. Part B, Molecular and developmental evolution 20120601
The pro-apoptotic effect of quercetin in cancer cell lines requires ERβ-dependent signals. Journal of cellular physiology 20120501
Alteration of Y-box binding protein-1 expression modifies the response to endocrine therapy in estrogen receptor-positive breast cancer. Breast cancer research and treatment 20120501
Dose-dependent change in biomarkers during neoadjuvant endocrine therapy with fulvestrant: results from NEWEST, a randomized Phase II study. Breast cancer research and treatment 20120501
Insulin-like growth factor binding protein 7 modulates estrogen-induced trophoblast proliferation and invasion in HTR-8 and JEG-3 cells. Cell biochemistry and biophysics 20120501
17β-Estradiol attenuates hypoxic pulmonary hypertension via estrogen receptor-mediated effects. American journal of respiratory and critical care medicine 20120501
Estrogen stimulates leptin receptor expression in ATDC5 cells via the estrogen receptor and extracellular signal-regulated kinase pathways. The Journal of endocrinology 20120501
Estrogen receptor alpha mediates progestin-induced mammary tumor growth by interacting with progesterone receptors at the cyclin D1/MYC promoters. Cancer research 20120501
[Preliminary study of estrogen effects on calcium free smooth muscle cells at the endometrial-myometrial interface in uteri with adenomyosis]. Zhonghua fu chan ke za zhi 20120501
Nanomolar dose of bisphenol A rapidly modulates spinogenesis in adult hippocampal neurons. Molecular and cellular endocrinology 20120404
17α-Ethinylestradiol and nonylphenol affect the development of forebrain GnRH neurons through an estrogen receptors-dependent pathway. Reproductive toxicology (Elmsford, N.Y.) 20120401
Diesel exhaust particulate extracts inhibit transcription of nuclear respiratory factor-1 and cell viability in human umbilical vein endothelial cells. Archives of toxicology 20120401
17β-Estradiol regulates cyclin A1 and cyclin B1 gene expression in adult rat seminiferous tubules. Journal of molecular endocrinology 20120401
Estrogen- and xenoestrogen-induced ERK signaling in pituitary tumor cells involves estrogen receptor-α interactions with G protein-αi and caveolin I. Steroids 20120401
Regulation of leptin expression by 17beta-estradiol in human placental cells involves membrane associated estrogen receptor alpha. Biochimica et biophysica acta 20120401
The terminal substituents of 7α, 6-hexanyl derivatives of estradiol determine their selective estrogen receptor modulator versus agonist activities. Steroids 20120401
2-Morpholinoisoflav-3-enes as flexible intermediates in the synthesis of phenoxodiol, isophenoxodiol, equol and analogues: vasorelaxant properties, estrogen receptor binding and Rho/RhoA kinase pathway inhibition. Bioorganic & medicinal chemistry 20120401
Phase II trial of exemestane in combination with fulvestrant in postmenopausal women with advanced, hormone-responsive breast cancer. Clinical breast cancer 20120401
Identification of modulators of hair cell regeneration in the zebrafish lateral line. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120307
Repeated and long-term treatment with physiological concentrations of resveratrol promotes NO production in vascular endothelial cells. The British journal of nutrition 20120301
The role of estrogen receptor α and β in regulating vascular smooth muscle cell proliferation is based on sex. The Journal of surgical research 20120301
Combining the multitargeted tyrosine kinase inhibitor vandetanib with the antiestrogen fulvestrant enhances its antitumor effect in non-small cell lung cancer. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120301
Cytoplasmic estrogen receptor β as a potential marker in human non-small cell lung carcinoma. Expert opinion on therapeutic targets 20120301
Estrogen-related MxA transcriptional variation in hepatitis C virus-infected patients. Translational research : the journal of laboratory and clinical medicine 20120301
Drug-targeted inhibition of peroxisome proliferator-activated receptor-gamma enhances the chemopreventive effect of anti-estrogen therapy. Oncotarget 20120301
Ugonin K-stimulated osteogenesis involves estrogen receptor-dependent activation of non-classical Src signaling pathway and classical pathway. European journal of pharmacology 20120215
Phthalate esters modulate the differentiation and maturation of mouse peripheral blood mononuclear cell-derived dendritic cells. Journal of applied toxicology : JAT 20120201
Estrogen and insulin-like growth factor-I (IGF-I) independently down-regulate critical repressors of breast cancer growth. Breast cancer research and treatment 20120201
Effect of pollen from Typha angustata on hydrogen peroxide induced toxicity in osteoblastic MC3T3-E1 cells. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20120201
Synergistic effects of parabens on the induction of calbindin-D(9k) gene expression act via a progesterone receptor-mediated pathway in GH3 cells. Human & experimental toxicology 20120201
Involvement of estrogen receptors in the resveratrol-mediated increase in dopamine transporter in human dopaminergic neurons and in striatum of female mice. Neuropharmacology 20120201
Rapid estrogenic effects on TMJ-responsive brainstem neurons. Journal of dental research 20120201
Nuclear estrogen receptor-mediated Notch signaling and GPR30-mediated PI3K/AKT signaling in the regulation of endometrial cancer cell proliferation. Oncology reports 20120201
Bisphenol A exposure modifies methylation of imprinted genes in mouse oocytes via the estrogen receptor signaling pathway. Histochemistry and cell biology 20120201
A comparative study of the effect of 17β-estradiol and estriol on peripheral pain behavior in rats. Steroids 20120201
Central estrogenic pathways protect against the depressant action of acute nicotine on reflex tachycardia in female rats. Toxicology and applied pharmacology 20120201
[Pharmacological and clinical profiles of Fulvestrant (Faslodex(®)) in the treatment of advanced or recurrenced breast cancer]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20120201
Potential estrogenic activity of triclosan in the uterus of immature rats and rat pituitary GH3 cells. Toxicology letters 20120125
Effects of nonylphenol on aldosterone release from rat zona glomerulosa cells. Chemico-biological interactions 20120105
Estrogen receptors and type 1 metabotropic glutamate receptors are interdependent in protecting cortical neurons against β-amyloid toxicity. Molecular pharmacology 20120101
Metalloestrogenic effects of quantum dots. Nanomedicine (London, England) 20120101
Estrogen plus estrogen receptor antagonists alter mineral production by osteoblasts in vitro. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20120101
Estrogen and progesterone play pivotal roles in endothelial progenitor cell proliferation. Reproductive biology and endocrinology : RB&E 20120101
Estrogen receptor-alpha 36 mediates mitogenic antiestrogen signaling in ER-negative breast cancer cells. PloS one 20120101
Endocrine disruptor regulation of microRNA expression in breast carcinoma cells. PloS one 20120101
Current approaches to the management of Her2-negative metastatic breast cancer. Breast cancer research : BCR 20120101
Inhibition of ERβ induces resistance to cisplatin by enhancing Rad51-mediated DNA repair in human medulloblastoma cell lines. PloS one 20120101
Molecular target based combinational therapeutic approaches in thyroid cancer. Journal of translational medicine 20120101
The role of estrogen receptor alpha in mediating chemoresistance in breast cancer cells. Journal of experimental & clinical cancer research : CR 20120101
Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer. PloS one 20120101
Effects of 4-nonylphenol and/or diisononylphthalate on THP-1 cells: impact of endocrine disruptors on human immune system parameters. International journal of immunopathology and pharmacology 20120101
Genistein stimulates jejunal chloride secretion via sex-dependent, estrogen receptor or adenylate cyclase mechanisms. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
Puerarin exerted anti-osteoporotic action independent of estrogen receptor-mediated pathway. Journal of nutritional science and vitaminology 20120101
[The role of estrogen receptor alpha in breast cancer cell proliferation mediated by progestins]. Medicina 20120101
The antiestrogens tamoxifen and fulvestrant abolish estrogenic impacts of 17α-ethinylestradiol on male calling behavior of Xenopus laevis. PloS one 20120101
Estrogen and progesterone regulate p27kip1 levels via the ubiquitin-proteasome system: pathogenic and therapeutic implications for endometrial cancer. PloS one 20120101
Disruption of 3D MCF-12A breast cell cultures by estrogens--an in vitro model for ER-mediated changes indicative of hormonal carcinogenesis. PloS one 20120101
Cajaninstilbene acid relaxes rat renal arteries: roles of Ca2+ antagonism and protein kinase C-dependent mechanism. PloS one 20120101
The DEK oncogene is a target of steroid hormone receptor signaling in breast cancer. PloS one 20120101
In vivo and in vitro evaluation of the estrogenic properties of the 17β-(butylamino)-1,3,5(10)-estratrien-3-ol (buame) related to 17β-estradiol. Pharmacological reports : PR 20120101
Low concentrations of o,p'-DDT inhibit gene expression and prostaglandin synthesis by estrogen receptor-independent mechanism in rat ovarian cells. PloS one 20120101
Dual IGF-1R/InsR inhibitor BMS-754807 synergizes with hormonal agents in treatment of estrogen-dependent breast cancer. Cancer research 20111215
17β-estradiol represses myogenic differentiation by increasing ubiquitin-specific peptidase 19 through estrogen receptor α. The Journal of biological chemistry 20111202
Estradiol-mediated suppression of CYP1B1 expression in mouse MA-10 Leydig cells is independent of protein kinase A and estrogen receptor. Molecular and cellular biochemistry 20111201
Low concentrations of bisphenol A induce mouse spermatogonial cell proliferation by G protein-coupled receptor 30 and estrogen receptor-α. Environmental health perspectives 20111201
Estrogen upregulates hepatic apolipoprotein M expression via the estrogen receptor. Biochimica et biophysica acta 20111201
Tamoxifen and its metabolites cause acute vasorelaxation of aortic rings by inducing vasodilator prostanoid synthesis. Journal of cardiovascular pharmacology 20111201
Estrogen increases nitric-oxide production in human bronchial epithelium. The Journal of pharmacology and experimental therapeutics 20111201
Effects of an estrogen receptor antagonist on proliferation, prolactin secretion and growth factor expression in the MMQ pituitary prolactinoma cell line. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20111201
Nursing perspectives on fulvestrant for the treatment of postmenopausal women with metastatic breast cancer. Clinical journal of oncology nursing 20111201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Puerarin activates endothelial nitric oxide synthase through estrogen receptor-dependent PI3-kinase and calcium-dependent AMP-activated protein kinase. Toxicology and applied pharmacology 20111115
Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells. Cancer biology & therapy 20111115
Combination treatment with fulvestrant and various cytotoxic agents (doxorubicin, paclitaxel, docetaxel, vinorelbine, and 5-fluorouracil) has a synergistic effect in estrogen receptor-positive breast cancer. Cancer science 20111101
Permanent oviduct posteriorization after neonatal exposure to the phytoestrogen genistein. Environmental health perspectives 20111101
Activation of the annexin A1 pathway underlies the protective effects exerted by estrogen in polymorphonuclear leukocytes. Arteriosclerosis, thrombosis, and vascular biology 20111101
ERβ-specific agonists and genistein inhibit proliferation and induce apoptosis in the large and small intestine. Carcinogenesis 20111101
A kinome-wide screen identifies the insulin/IGF-I receptor pathway as a mechanism of escape from hormone dependence in breast cancer. Cancer research 20111101
CEBPD suppresses prolactin expression and prolactinoma cell proliferation. Molecular endocrinology (Baltimore, Md.) 20111101
[Hormone therapy and breast cancer]. Bulletin du cancer 20111101
Role of fulvestrant in the management of postmenopausal breast cancer. Expert review of anticancer therapy 20111101
Effects of bisphenol A and triclocarban on brain-specific expression of aromatase in early zebrafish embryos. Proceedings of the National Academy of Sciences of the United States of America 20111025
Endocrine disrupting effects of zearalenone, alpha- and beta-zearalenol at the level of nuclear receptor binding and steroidogenesis. Toxicology letters 20111010
The anti-oestrogen fulvestrant (ICI 182,780) reduces the androgen receptor expression, ERK1/2 phosphorylation and cell proliferation in the rat ventral prostate. International journal of andrology 20111001
Aroclor1254 interferes with estrogen receptor-mediated neuroprotection against beta-amyloid toxicity in cholinergic SN56 cells. Neurochemistry international 20111001
Attenuation of atherogenesis via the anti-inflammatory effects of the selective estrogen receptor beta modulator 8β-VE2. Journal of cardiovascular pharmacology 20111001
A phase II neoadjuvant trial of anastrozole, fulvestrant, and gefitinib in patients with newly diagnosed estrogen receptor positive breast cancer. Breast cancer research and treatment 20111001
Progesterone and 17β-estradiol increase differentiation of mouse embryonic stem cells to motor neurons. IUBMB life 20111001
Effect of conceptus secretions on HOXA10 and PTGS2 gene expression, and PGE2 release in co-cultured luminal epithelial and stromal cells of the porcine endometrium at the time of early implantation. Theriogenology 20110915
Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators. Proceedings of the National Academy of Sciences of the United States of America 20110906
Estrogen or estrogen receptor agonist inhibits lipopolysaccharide induced microglial activation and death. Neurochemical research 20110901
Conserved aquaporin 4 levels associated with reduction of brain edema are mediated by estrogen in the ischemic brain after experimental stroke. Biochimica et biophysica acta 20110901
Estrogen regulation of the dopamine-activated GIRK channel in pituitary lactotrophs: implications for regulation of prolactin release during the estrous cycle. American journal of physiology. Regulatory, integrative and comparative physiology 20110901
Emerging data on the efficacy and safety of fulvestrant, a unique antiestrogen therapy for advanced breast cancer. Expert opinion on drug safety 20110901
Phospholipid hydroperoxide glutathione peroxidase gene is regulated via an estrogen and estrogen receptor signaling in cultured mouse fetuses. In vitro cellular & developmental biology. Animal 20110901
Bisphenol-A rapidly enhanced passive avoidance memory and phosphorylation of NMDA receptor subunits in hippocampus of young rats. Toxicology and applied pharmacology 20110901
DNA site-specific N3-adenine methylation targeted to estrogen receptor-positive cells. Bioorganic & medicinal chemistry 20110901
Management of patients with metastatic breast cancer. Advances in therapy 20110901
Synergistic chemoprotective mechanisms of dietary phytoestrogens in a select combination against prostate cancer. The Journal of nutritional biochemistry 20110801
The presence of a membrane-bound progesterone receptor sensitizes the estradiol-induced effect on the proliferation of human breast cancer cells. Menopause (New York, N.Y.) 20110801
STX, a novel nonsteroidal estrogenic compound, induces rapid action in primate GnRH neuronal calcium dynamics and peptide release. Endocrinology 20110801
Efficacy of pharmacological estrogen receptor antagonists in blocking activation of zebrafish estrogen receptors. General and comparative endocrinology 20110801
Effect of ozonation on the estrogenicity and androgenicity of oil sands process-affected water. Environmental science & technology 20110801
Fulvestrant revisited: efficacy and safety of the 500-mg dose. Clinical breast cancer 20110801
Can the increase in breast cancer observed in the estrogen plus progestin arm of the Women's Health Initiative trial be explained by progesterone receptor membrane component 1? Menopause (New York, N.Y.) 20110801
The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy. Biochemical pharmacology 20110715
Fluoroestradiol positron emission tomography reveals differences in pharmacodynamics of aromatase inhibitors, tamoxifen, and fulvestrant in patients with metastatic breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20110715
Effects of PCB126 and 17β-oestradiol on endothelium-derived vasoactive factors in human endothelial cells. Toxicology 20110711
Estradiol and progesterone modulate halothane-induced liver injury in mice. Toxicology letters 20110704
Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers. Breast cancer research and treatment 20110701
Combined Src and ER blockade impairs human breast cancer proliferation in vitro and in vivo. Breast cancer research and treatment 20110701
17β-estradiol aggravates temporomandibular joint inflammation through the NF-κB pathway in ovariectomized rats. Arthritis and rheumatism 20110701
Tamoxifen regulation of bone growth and endocrine function in the ovariectomized rat: discrimination of responses involving estrogen receptor α/estrogen receptor β, G protein-coupled estrogen receptor, or estrogen-related receptor γ using fulvestrant (ICI 182780). The Journal of pharmacology and experimental therapeutics 20110701
An in vitro model showing adaptation to long-term oestrogen deprivation highlights the clinical potential for targeting kinase pathways in combination with aromatase inhibition. Steroids 20110701
[Effect of estrogen on mismatch repair gene expression in colon cancer cells]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110701
Prolonged time to progression with fulvestrant for metastatic breast cancer. Medical oncology (Northwood, London, England) 20110601
Duodenal and renal transient receptor potential vanilloid 6 is regulated by sex steroid hormones, estrogen and progesterone, in immature rats. The Journal of veterinary medical science 20110601
BCAR3/AND-34 can signal independent of complex formation with CAS family members or the presence of p130Cas. Cellular signalling 20110601
Costunolide stimulates the function of osteoblastic MC3T3-E1 cells. International immunopharmacology 20110601
Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer. Endocrine-related cancer 20110601
Activation of mutated K-ras in donor endometrial epithelium and stroma promotes lesion growth in an intact immunocompetent murine model of endometriosis. The Journal of pathology 20110601
Antiproliferative effect of estrogen in vascular smooth muscle cells is mediated by Kruppel-like factor-4 and manganese superoxide dismutase. Basic research in cardiology 20110601
The effects of wild ginger (Costus speciosus (Koen) Smith) rhizome extract and diosgenin on rat uterine contractions. Reproductive sciences (Thousand Oaks, Calif.) 20110601
Hormonal therapy plus bevacizumab in postmenopausal patients who have hormone receptor-positive metastatic breast cancer: a phase II Trial of the Sarah Cannon Oncology Research Consortium. Clinical breast cancer 20110601
Biomimetic syntheses and antiproliferative activities of racemic, natural (-), and unnnatural (+) glyceollin I. Journal of medicinal chemistry 20110526
High content imaging-based assay to classify estrogen receptor-α ligands based on defined mechanistic outcomes. Gene 20110515
Role of estrogen receptor-dependent upregulation of P38 MAPK/heme oxygenase 1 in resveratrol-mediated attenuation of intestinal injury after trauma-hemorrhage. Shock (Augusta, Ga.) 20110501
Down-regulation of oestrogen receptor-β associates with transcriptional co-regulator PATZ1 delocalization in human testicular seminomas. The Journal of pathology 20110501
Spinal estrogen receptor alpha mediates estradiol-induced pronociception in a visceral pain model in the rat. Pain 20110501
Overcoming resistance to fulvestrant (ICI182,780) by downregulating the c-ABL proto-oncogene in breast cancer. Molecular carcinogenesis 20110501
p53 status influences response to tamoxifen but not to fulvestrant in breast cancer cell lines. International journal of cancer 20110415
Bortezomib enhances the efficacy of fulvestrant by amplifying the aggregation of the estrogen receptor, which leads to a proapoptotic unfolded protein response. Clinical cancer research : an official journal of the American Association for Cancer Research 20110415
Estrogen regulates tumor growth through a nonclassical pathway that includes the transcription factors ERβ and KLF5. Science signaling 20110412
Estrogen receptor alpha pathway is involved in leptin-induced ovarian cancer cell growth. Carcinogenesis 20110401
Resveratrol interacts with estrogen receptor-β to inhibit cell replicative growth and enhance stress resistance by upregulating mitochondrial superoxide dismutase. Free radical biology & medicine 20110401
Notch/neurogenin 3 signalling is involved in the neuritogenic actions of oestradiol in developing hippocampal neurones. Journal of neuroendocrinology 20110401
Estrogen receptor-β signaling modulates epithelial barrier function. American journal of physiology. Gastrointestinal and liver physiology 20110401
Differential estrogenic effects of the persistent organochlorine pesticides dieldrin, endosulfan, and lindane in primary neuronal cultures. Toxicological sciences : an official journal of the Society of Toxicology 20110401
Differential effects of a complex organochlorine mixture on the proliferation of breast cancer cell lines. Environmental research 20110401
Cross talk between glucocorticoid and estrogen receptors occurs at a subset of proinflammatory genes. Journal of immunology (Baltimore, Md. : 1950) 20110401
Fulvestrant for advanced male breast cancer patients: a case series. Annals of oncology : official journal of the European Society for Medical Oncology 20110401
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways. Oncogene 20110303
The antidepressant-like effect of the 3β-hydroxysteroid dehydrogenase inhibitor trilostane involves a regulation of β-type estrogen receptors. Psychopharmacology 20110301
Genistein ameliorates learning and memory deficits in amyloid β(1-40) rat model of Alzheimer's disease. Neurobiology of learning and memory 20110301
Regional genomic regulation of cardiac sodium-calcium exchanger by oestrogen. The Journal of physiology 20110301
Estrogens promote invasion of prostate cancer cells in a paracrine manner through up-regulation of matrix metalloproteinase 2 in prostatic stromal cells. Endocrinology 20110301
Fulvestrant: a review of its use in the management of hormone receptor-positive metastatic breast cancer in postmenopausal women. Drugs 20110212
Inhibition of focal adhesion kinase suppresses the adverse phenotype of endocrine-resistant breast cancer cells and improves endocrine response in endocrine-sensitive cells. Breast cancer research and treatment 20110201
Testosterone and 17β-estradiol have opposite effects on podocyte apoptosis that precedes glomerulosclerosis in female estrogen receptor knockout mice. Kidney international 20110201
Distinctive functions of p160 steroid receptor coactivators in proliferation of an estrogen-independent, tamoxifen-resistant breast cancer cell line. Endocrine-related cancer 20110201
Phase II study of fulvestrant in recurrent/metastatic endometrial carcinoma: a Gynecologic Oncology Group study. Gynecologic oncology 20110201
Dual effects of estrogen on vascular smooth muscle cells: receptor-mediated proliferative vs. metabolite-induced pro-senescent actions. Steroids 20110201
Complete estrogen receptor blocker ICI182,780 promotes the proliferation of vascular smooth muscle cells. Acta biochimica et biophysica Sinica 20110201
Irosustat: a first-generation steroid sulfatase inhibitor in breast cancer. Expert review of anticancer therapy 20110201
Fulvestrant in the management of postmenopausal women with advanced, endocrine-responsive breast cancer. Future oncology (London, England) 20110201
Cytokine receptor CXCR4 mediates estrogen-independent tumorigenesis, metastasis, and resistance to endocrine therapy in human breast cancer. Cancer research 20110115
The cooked meat-derived mammary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine promotes invasive behaviour of breast cancer cells. Toxicology 20110111
Estradiol-regulated proline-rich acid protein 1 is repressed by class I histone deacetylase and functions in peri-implantation mouse uterus. Molecular and cellular endocrinology 20110101
In vivo treatments with fulvestrant and anastrozole differentially affect gene expression in the rat efferent ductules. Biology of reproduction 20110101
Estrogen induces stromal cell-derived factor 1 (SDF-1/CXCL12) production in human endometrial stromal cells: a possible role of endometrial epithelial cell growth. Fertility and sterility 20110101
Bisphenol A induces a rapid activation of Erk1/2 through GPR30 in human breast cancer cells. Environmental pollution (Barking, Essex : 1987) 20110101
Sex differences in the analgesic effects of ICI 182,780 and Flutamide on ureteral calculosis in rats. Hormones and behavior 20110101
Fulvestrant 250 mg versus anastrozole for Chinese patients with advanced breast cancer: results of a multicentre, double-blind, randomised phase III trial. Cancer chemotherapy and pharmacology 20110101
Benefits of early and prolonged fulvestrant treatment in 848 postmenopausal advanced breast cancer patients. Breast cancer research and treatment 20110101
Estrogen receptor-α but not -β or GPER inhibits high glucose-induced human VSMC proliferation: potential role of ROS and ERK. The Journal of clinical endocrinology and metabolism 20110101
SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20110101
New hydroxystilbenoid derivatives endowed with neuroprotective activity and devoid of interference with estrogen and aryl hydrocarbon receptor-mediated transcription. Bioorganic & medicinal chemistry 20110101
Acquired endocrine resistance in breast cancer: implications for tumour metastasis. Frontiers in bioscience (Landmark edition) 20110101
Bisphenol A induces otolith malformations during vertebrate embryogenesis. BMC developmental biology 20110101
Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer. Breast cancer research : BCR 20110101
Fulvestrant-induced expression of ErbB3 and ErbB4 receptors sensitizes oestrogen receptor-positive breast cancer cells to heregulin β1. Breast cancer research : BCR 20110101
Assessing oestrogenic effects of brominated flame retardants hexabromocyclododecane and tetrabromobisphenol A on MCF-7 cells. Folia biologica 20110101
Response of estrogen receptor-positive breast cancer tumorspheres to antiestrogen treatments. PloS one 20110101
Tamoxifen in early-stage estrogen receptor-positive breast cancer: overview of clinical use and molecular biomarkers for patient selection. OncoTargets and therapy 20110101
Elevated insulin-like growth factor 1 receptor signaling induces antiestrogen resistance through the MAPK/ERK and PI3K/Akt signaling routes. Breast cancer research : BCR 20110101
Evaluation of cell cycle arrest in estrogen responsive MCF-7 breast cancer cells: pitfalls of the MTS assay. PloS one 20110101
Induction of stable drug resistance in human breast cancer cells using a combinatorial zinc finger transcription factor library. PloS one 20110101
Ki67 proliferation in core biopsies versus surgical samples - a model for neo-adjuvant breast cancer studies. BMC cancer 20110101
Mechanisms of genistein protection on pancreas cell damage in high glucose condition. Internal medicine (Tokyo, Japan) 20110101
Crosstalk between integrin αvβ3 and estrogen receptor-α is involved in thyroid hormone-induced proliferation in human lung carcinoma cells. PloS one 20110101
Metformin represses self-renewal of the human breast carcinoma stem cells via inhibition of estrogen receptor-mediated OCT4 expression. PloS one 20110101
PAX2 is activated by estradiol in breast cancer cells of the luminal subgroup selectively, to confer a low invasive phenotype. Molecular cancer 20110101
Chronic leptin treatment sensitizes MCF-7 breast cancer cells to estrogen. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101
Inhibition of aryl hydrocarbon receptor-dependent transcription by resveratrol or kaempferol is independent of estrogen receptor α expression in human breast cancer cells. Cancer letters 20101228
The effect of intra-locus coeruleus injection of 17beta-estradiol on inflammatory pain modulation in male rat. Behavioural brain research 20101225
Loss of BRCA1 leads to an increased sensitivity to Bisphenol A. Toxicology letters 20101215
Three dose regimens of fulvestrant in postmenopausal Japanese women with advanced breast cancer: results from a double-blind, phase II comparative study (FINDER1). Annals of oncology : official journal of the European Society for Medical Oncology 20101201
Estradiol regulates expression of polysialated neural cell adhesion molecule by human vascular endothelial cells. Reproductive sciences (Thousand Oaks, Calif.) 20101201
Effects and mechanisms of nonylphenol on corticosterone release in rat zona fasciculata-reticularis cells. Toxicological sciences : an official journal of the Society of Toxicology 20101201
Bisphenol-A rapidly promotes dynamic changes in hippocampal dendritic morphology through estrogen receptor-mediated pathway by concomitant phosphorylation of NMDA receptor subunit NR2B. Toxicology and applied pharmacology 20101201
Mechanical loading-related bone gain is enhanced by tamoxifen but unaffected by fulvestrant in female mice. Endocrinology 20101201
Trefoil factor 3 is oncogenic and mediates anti-estrogen resistance in human mammary carcinoma. Neoplasia (New York, N.Y.) 20101201
Bisphenol A impairs the double-strand break repair machinery in the germline and causes chromosome abnormalities. Proceedings of the National Academy of Sciences of the United States of America 20101123
Small proline-rich protein 2 family is a cluster of genes induced by estrogenic compounds through nuclear estrogen receptors in the mouse uterus. Reproductive toxicology (Elmsford, N.Y.) 20101101
Progesterone increases systemic and local uterine proportions of CD4+CD25+ Treg cells during midterm pregnancy in mice. Endocrinology 20101101
Research resource: estrogen-driven prolactin-mediated gene-expression networks in hormone-induced prostatic intraepithelial neoplasia. Molecular endocrinology (Baltimore, Md.) 20101101
17β-estradiol inhibits the production of infectious particles of hepatitis C virus. Microbiology and immunology 20101101
The protective effect of 17beta-estradiol postconditioning against hypoxia/reoxygenation injury in human gastric epithelial cells. European journal of pharmacology 20101025
Results of the CONFIRM phase III trial comparing fulvestrant 250 mg with fulvestrant 500 mg in postmenopausal women with estrogen receptor-positive advanced breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020
Insights into the place of fulvestrant for the treatment of advanced endocrine responsive breast cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020
Effects of estrogen on breast cancer development: Role of estrogen receptor independent mechanisms. International journal of cancer 20101015
Bisphenol-A interferes with estradiol-mediated protection in osteoarthritic chondrocytes. Toxicology letters 20101005
Progesterone is primary regulator of Cdk2ap1 gene expression and tissue-specific expression in the uterus. Journal of endocrinological investigation 20101001
Efavirenz directly modulates the oestrogen receptor and induces breast cancer cell growth. HIV medicine 20101001
Superinduction of estrogen receptor mediated gene expression in luciferase based reporter gene assays is mediated by a post-transcriptional mechanism. The Journal of steroid biochemistry and molecular biology 20101001
Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function. Hepatology (Baltimore, Md.) 20101001
Chrysoeriol isolated from Eurya cilliata leaves protects MC3T3-E1 cells against hydrogen peroxide-induced inhibition of osteoblastic differentiation. Journal of applied toxicology : JAT 20101001
ETAR antagonist ZD4054 exhibits additive effects with aromatase inhibitors and fulvestrant in breast cancer therapy, and improves in vivo efficacy of anastrozole. Breast cancer research and treatment 20100901
17beta-estradiol mediated protection against vascular leak after hemorrhagic shock: role of estrogen receptors and apoptotic signaling. Shock (Augusta, Ga.) 20100901
Results of a phase II study comparing three dosing regimens of fulvestrant in postmenopausal women with advanced breast cancer (FINDER2). Breast cancer research and treatment 20100901
17 β-estradiol rapidly increases ATP-sensitive potassium channel activity in gonadotropin-releasing hormone neurons [corrected] via a protein kinase signaling pathway. Endocrinology 20100901
Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells. Journal of medicinal chemistry 20100826
Mechanisms of estrogen receptor antagonism toward p53 and its implications in breast cancer therapeutic response and stem cell regulation. Proceedings of the National Academy of Sciences of the United States of America 20100824
Unexpected hormonal activity of a catechol equine estrogen metabolite reveals reversible glutathione conjugation. Chemical research in toxicology 20100816
Intratumoral localization of aromatase and interaction between stromal and parenchymal cells in the non-small cell lung carcinoma microenvironment. Cancer research 20100815
Sensitive and rapid high-performance liquid chromatography tandem mass spectrometry method for estimation of fulvestrant in rabbit plasma. Biomedical chromatography : BMC 20100801
The assessment of estrogenic or anti-estrogenic activity of chemicals by the human stably transfected estrogen sensitive MELN cell line: results of test performance and transferability. Reproductive toxicology (Elmsford, N.Y.) 20100801
Optimization and prevalidation of the in vitro ERalpha CALUX method to test estrogenic and antiestrogenic activity of compounds. Reproductive toxicology (Elmsford, N.Y.) 20100801
Expression and signaling of G protein-coupled estrogen receptor 1 (GPER) in rat sertoli cells. Biology of reproduction 20100801
Estradiol-17beta stimulates specific receptor and endogenous nitric oxide-dependent dynamic endothelial protein S-nitrosylation: analysis of endothelial nitrosyl-proteome. Endocrinology 20100801
17α-Ethinylestradiol rapidly alters transcript levels of murine coagulation genes via estrogen receptor α. Journal of thrombosis and haemostasis : JTH 20100801
Genomic action of permanently charged tamoxifen derivatives via estrogen receptor-alpha. Bioorganic & medicinal chemistry 20100801
Dilation of epicardial coronary arteries by the G protein-coupled estrogen receptor agonists G-1 and ICI 182,780. Pharmacology 20100801
Cardiac oxytocin receptor blockade stimulates adverse cardiac remodeling in ovariectomized spontaneously hypertensive rats. American journal of physiology. Heart and circulatory physiology 20100801
A better injection site. The American journal of nursing 20100801
Gender-specific reduction in contraction is associated with increased estrogen receptor expression in single vascular smooth muscle cells of female rat. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100801
Okadaic acid induces tau phosphorylation in SH-SY5Y cells in an estrogen-preventable manner. Brain research 20100723
Formononetin, an isoflavone, relaxes rat isolated aorta through endothelium-dependent and endothelium-independent pathways. The Journal of nutritional biochemistry 20100701
17Beta-estradiol enhances leptin expression in human placental cells through genomic and nongenomic actions. Biology of reproduction 20100701
Ciliary beat frequency controlled by oestradiol and progesterone during ovarian cycle in guinea-pig Fallopian tube. Experimental physiology 20100701
ICI 182,780 induces P-cadherin overexpression in breast cancer cells through chromatin remodelling at the promoter level: a role for C/EBPbeta in CDH3 gene activation. Human molecular genetics 20100701
Effect of Estradiol-17beta on protein synthesis and degradation rates in fused bovine satellite cell cultures. Domestic animal endocrinology 20100701
Asymmetric regulation by estrogen at the cholinergic gene locus in differentiated NG108-15 neuronal cells. Life sciences 20100605
In vitro effects of bisphenol A on developing hypothalamic neurons. Toxicology 20100604
Artemin is estrogen regulated and mediates antiestrogen resistance in mammary carcinoma. Oncogene 20100603
Fulvestrant (ICI 182,780) sensitizes breast cancer cells expressing estrogen receptor alpha to vinblastine and vinorelbine. Breast cancer research and treatment 20100601
Breast cancer cells can switch between estrogen receptor alpha and ErbB signaling and combined treatment against both signaling pathways postpones development of resistance. Breast cancer research and treatment 20100601
Breast cancer cell growth inhibition by phenethyl isothiocyanate is associated with down-regulation of oestrogen receptor-alpha36. Journal of cellular and molecular medicine 20100601
Activity of fulvestrant in HER2-overexpressing advanced breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology 20100601
Effect of selective estrogen receptor modulator/raloxifene analogue on proliferation and collagen metabolism of tendon fibroblast. Connective tissue research 20100601
Membrane-impermeable estrogen is involved in regulation of calbindin-D9k expression via non-genomic pathways in a rat pituitary cell line, GH3 cells. Toxicology in vitro : an international journal published in association with BIBRA 20100601
Cross-talk between non-genomic and genomic signalling pathways--distinct effect profiles of environmental estrogens. Toxicology and applied pharmacology 20100601
Intracellular, not membrane, estrogen receptors control vitellogenin synthesis in the rainbow trout. General and comparative endocrinology 20100601
Optical redox ratio differentiates breast cancer cell lines based on estrogen receptor status. Cancer research 20100601
FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance. Oncogene 20100520
Rapid effects of phytoestrogens on human colonic smooth muscle are mediated by oestrogen receptor beta. Molecular and cellular endocrinology 20100514
Activation of G protein-coupled receptor 30 modulates hormone secretion and counteracts cytokine-induced apoptosis in pancreatic islets of female mice. Molecular and cellular endocrinology 20100514
Delayed activation of extracellular-signal-regulated kinase 1/2 is involved in genistein- and equol-induced cell proliferation and estrogen-receptor-alpha-mediated transcription in MCF-7 breast cancer cells. The Journal of nutritional biochemistry 20100501
E-cadherin mediates the aggregation of breast cancer cells induced by tamoxifen and epidermal growth factor. Breast cancer research and treatment 20100501
Experience with fulvestrant acetate in castration-resistant prostate cancer patients. Annals of oncology : official journal of the European Society for Medical Oncology 20100501
Therapeutically relevant concentrations of raloxifene dilate pressurized rat resistance arteries via calcium-dependent endothelial nitric oxide synthase activation. Arteriosclerosis, thrombosis, and vascular biology 20100501
Regulation of ERRalpha gene expression by estrogen receptor agonists and antagonists in SKBR3 breast cancer cells: differential molecular mechanisms mediated by g protein-coupled receptor GPR30/GPER-1. Molecular endocrinology (Baltimore, Md.) 20100501
Suppression of ERalpha activity by COUP-TFII is essential for successful implantation and decidualization. Molecular endocrinology (Baltimore, Md.) 20100501
Cadmium promotes breast cancer cell proliferation by potentiating the interaction between ERalpha and c-Jun. Molecular endocrinology (Baltimore, Md.) 20100501
Steroidal regulation of Ihh and Gli1 expression in the rat uterus. Cell and tissue research 20100501
Estradiol-induced proliferation of papillary and follicular thyroid cancer cells is mediated by estrogen receptors alpha and beta. International journal of oncology 20100501
IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis. Molecular cancer therapeutics 20100501
Characterization of the pharmacophore properties of novel selective estrogen receptor downregulators (SERDs). Journal of medicinal chemistry 20100422
Estrogen receptor and Wnt signaling interact to regulate early gene expression in response to mechanical strain in osteoblastic cells. Biochemical and biophysical research communications 20100409
Differential action of chlorinated polycyclic aromatic hydrocarbons on aryl hydrocarbon receptor-mediated signaling in breast cancer cells. Environmental toxicology 20100401
Breast cancer-derived M543V mutation in helix 12 of estrogen receptor alpha inverts response to estrogen and SERMs. Breast cancer research and treatment 20100401
Resveratrol prevents endothelial dysfunction and aortic superoxide production after trauma hemorrhage through estrogen receptor-dependent hemeoxygenase-1 pathway. Critical care medicine 20100401
Stimulatory effects of the soy phytoestrogen genistein on noradrenaline transporter and serotonin transporter activity. Molecular nutrition & food research 20100401
Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERalpha pathway in human breast cancer cells. Toxicological sciences : an official journal of the Society of Toxicology 20100401
Estradiol inhibits chondrogenic differentiation of mesenchymal stem cells via nonclassic signaling. Arthritis and rheumatism 20100401
Fulvestrant: a unique antiendocrine agent for estrogen-sensitive breast cancer. Expert opinion on pharmacotherapy 20100401
The Wilms' tumor suppressor WT1 induces estrogen-independent growth and anti-estrogen insensitivity in ER-positive breast cancer MCF7 cells. Oncology reports 20100401
Estrogen receptor-mediated enhancement of venous relaxation in female rat: implications in sex-related differences in varicose veins. Journal of vascular surgery 20100401
Oestrogen receptor-beta signalling protects against transplanted skin tumour growth in the mouse. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100401
Mechano-transduction in osteoblastic cells involves strain-regulated estrogen receptor alpha-mediated control of insulin-like growth factor (IGF) I receptor sensitivity to Ambient IGF, leading to phosphatidylinositol 3-kinase/AKT-dependent Wnt/LRP5 receptor-independent activation of beta-catenin signaling. The Journal of biological chemistry 20100319
4-Hydroxytamoxifen inhibits K(+) currents in mouse ventricular myocytes. European journal of pharmacology 20100310
Fulvestrant in the treatment of advanced breast cancer: a systematic review and meta-analysis of randomized controlled trials. Critical reviews in oncology/hematology 20100301
Sex differences in estrogen receptor subcellular location and activity in lung adenocarcinoma cells. American journal of respiratory cell and molecular biology 20100301
Knockdown of ICB-1 gene enhanced estrogen responsiveness of ovarian and breast cancer cells. Endocrine-related cancer 20100301
The effects of beta-blockers on endothelial nitric oxide synthase immunoreactivity in the rat corpus cavernosum. Urology 20100301
The effects of pomegranate seed extract and beta-sitosterol on rat uterine contractions. Reproductive sciences (Thousand Oaks, Calif.) 20100301
Estrogen-regulated expression and distribution of Id-1 in the mouse uterus. Placenta 20100301
Estrogen receptor-alpha-interacting cytokeratins potentiate the antiestrogenic activity of fulvestrant. Cancer biology & therapy 20100301
Transcriptional activation of DNA-dependent protein kinase catalytic subunit gene expression by oestrogen receptor-alpha. EMBO reports 20100301
FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. Cancer research 20100301
Estrogen receptor regulates E2F1 expression to mediate tamoxifen resistance. Molecular cancer research : MCR 20100301
Estrogen utilization of IGF-1-R and EGF-R to signal in breast cancer cells. The Journal of steroid biochemistry and molecular biology 20100227
Oestrogen receptor-alpha contributes to the regulation of the hedgehog signalling pathway in ERalpha-positive gastric cancer. British journal of cancer 20100216
Both nongenomic and genomic effects are involved in estradiol's enhancing the phenotype of smooth muscle cells in cultured prostate stromal cells. The Prostate 20100215
Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications. Toxicology letters 20100215
Antiestrogens induce transforming growth factor beta-mediated immunosuppression in breast cancer. Cancer research 20100215
Suppressive effect on MDC and IP-10 expression in monocytes by endocrine disruptor chemicals. Inflammation 20100201
Zip6-attenuation promotes epithelial-to-mesenchymal transition in ductal breast tumor (T47D) cells. Experimental cell research 20100201
Hexachlorobenzene induces cell proliferation and IGF-I signaling pathway in an estrogen receptor alpha-dependent manner in MCF-7 breast cancer cell line. Toxicology letters 20100201
Effects of estrogen on synapsin I distribution in developing hypothalamic neurons. Neuroscience research 20100201
Induction of spermatogenic cell apoptosis in prepubertal rat testes irrespective of testicular steroidogenesis: a possible estrogenic effect of di(n-butyl) phthalate. Reproduction (Cambridge, England) 20100201
FKBPL regulates estrogen receptor signaling and determines response to endocrine therapy. Cancer research 20100201
Icariin protects against bone loss induced by oestrogen deficiency and activates oestrogen receptor-dependent osteoblastic functions in UMR 106 cells. British journal of pharmacology 20100201
Prognosis of hormone-dependent breast cancers: implications of the presence of dysfunctional transcriptional networks activated by insulin via the immune transcription factor T-bet. Cancer research 20100115
Notch-1 activates estrogen receptor-alpha-dependent transcription via IKKalpha in breast cancer cells. Oncogene 20100114
Cellular and molecular mechanisms of 17beta-estradiol postconditioning protection against gastric mucosal injury induced by ischemia/reperfusion in rats. Life sciences 20100102
Transferrin receptor (CD71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen. Breast cancer research and treatment 20100101
Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-gamma-inducible protein-10 by astrocytes exposed to inflammatory challenge in vitro. Glia 20100101
Ginsenoside Rb1 protects against 6-hydroxydopamine-induced oxidative stress by increasing heme oxygenase-1 expression through an estrogen receptor-related PI3K/Akt/Nrf2-dependent pathway in human dopaminergic cells. Toxicology and applied pharmacology 20100101
Absence of ligand-independent transcriptional activation of the estrogen receptor via the estrogen response element in pituitary lactotrophs in primary culture. The Journal of steroid biochemistry and molecular biology 20100101
Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators. Molecular endocrinology (Baltimore, Md.) 20100101
Environmental endocrine disruptors promote invasion and metastasis of SK-N-SH human neuroblastoma cells. Oncology reports 20100101
Modulation of cytokine expression in human myeloid dendritic cells by environmental endocrine-disrupting chemicals involves epigenetic regulation. Environmental health perspectives 20100101
Co-inhibition of BCL-W and BCL2 restores antiestrogen sensitivity through BECN1 and promotes an autophagy-associated necrosis. PloS one 20100101
Estrogen receptor-dependent regulation of CYP2B6 in human breast cancer cells. Biochimica et biophysica acta 20100101
Fulvestrant - a novel endocrine therapy for breast cancer. Current medicinal chemistry 20100101
Do we really need new trials on fulvestrant in prostate cancer? Onkologie 20100101
PSA decrease with fulvestrant acetate in a hormone-resistant metastatic prostate cancer patient. Onkologie 20100101
Estrogenic in vitro assay on mouse embryonic Leydig cells. The International journal of developmental biology 20100101
In vitro effects of oestrogens, antioestrogens and SERMs on pancreatic solid pseudopapillary neoplasm-derived primary cell culture. Cellular oncology : the official journal of the International Society for Cellular Oncology 20100101
Selective estrogen receptor down-regulator and selective estrogen receptor modulators differentially regulate lactotroph proliferation. PloS one 20100101
Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer. BMC cancer 20100101
Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-alpha and survivin. Breast cancer research : BCR 20100101
Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression. PloS one 20100101
The estrogen receptor influences microtubule-associated protein tau (MAPT) expression and the selective estrogen receptor inhibitor fulvestrant downregulates MAPT and increases the sensitivity to taxane in breast cancer cells. Breast cancer research : BCR 20100101
MYB suppresses differentiation and apoptosis of human breast cancer cells. Breast cancer research : BCR 20100101
Effects of 17 β-estradiol on lipopolysacharride-induced intracellular adhesion molecule-1 mRNA expression and Ca²+ homeostasis alteration in human endothelial cells. Vascular pharmacology 20100101
Genistein induced apoptotic cell death in adult T-cell leukemia cells through estrogen receptors. Bioscience, biotechnology, and biochemistry 20100101
Ligands specify estrogen receptor alpha nuclear localization and degradation. BMC cell biology 20100101
Estrogen stimulates proliferation and differentiation of neural stem/progenitor cells through different signal transduction pathways. International journal of molecular sciences 20100101
17alpha-Ethinylestradiol hinders nucleotide excision repair in zebrafish liver cells. Aquatic toxicology (Amsterdam, Netherlands) 20091213
Potent and selective steroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 7, an enzyme that catalyzes the reduction of the key hormones estrone and dihydrotestosterone. Journal of medicinal chemistry 20091210
Estradiol-induced estrogen receptor-alpha trafficking. The Journal of neuroscience : the official journal of the Society for Neuroscience 20091202
Tamoxifen and ICI 182,780 increase Bcl-2 levels and inhibit growth of breast carcinoma cells by modulating PI3K/AKT, ERK and IGF-1R pathways independent of ERalpha. Breast cancer research and treatment 20091201
17Beta-estradiol activates adenosine A(2a) receptor after subarachnoid hemorrhage. The Journal of surgical research 20091201
Clinical use of selective estrogen receptor modulators and down regulators with the main focus on breast cancer. Minerva ginecologica 20091201
Differential regulation of Akt phosphorylation in endometriosis. Reproductive biomedicine online 20091201
Antiproliferative activity of brown Cuban propolis extract on human breast cancer cells. Natural product communications 20091201
Novel dehydroepiandrosterone derivatives with antiapoptotic, neuroprotective activity. Journal of medicinal chemistry 20091112
Interdependence between heme oxygenase-1 induction and estrogen-receptor-beta signaling mediates photoimmune protection by UVA radiation in mice. The Journal of investigative dermatology 20091101
Predicting benefit from fulvestrant in pretreated metastatic breast cancer patients. Breast cancer research and treatment 20091101
Aromatase promoter I.f is regulated by estrogen receptor alpha (ESR1) in mouse hypothalamic neuronal cell lines. Biology of reproduction 20091101
Long-term estrogen exposure promotes carcinogen bioactivation, induces persistent changes in gene expression, and enhances the tumorigenicity of MCF-7 human breast cancer cells. Toxicology and applied pharmacology 20091101
An evaluation of estrogenic activity of parabens using uterine calbindin-d9k gene in an immature rat model. Toxicological sciences : an official journal of the Society of Toxicology 20091101
Fulvestrant in advanced male breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology 20091101
Melatonin-induced estrogen receptor alpha-mediated calbindin-D9k expression plays a role in H2O2-mediated cell death in rat pituitary GH3 cells. Journal of pineal research 20091101
The lecanindoles, nonsteroidal progestins from the terrestrial fungus Verticillium lecanii 6144. Journal of natural products 20091101
Estrogenic activity of xanthorrhizol isolated from curcuma xanthorrhiza ROXB. Biological & pharmaceutical bulletin 20091101
Dual activities of odorants on olfactory and nuclear hormone receptors. The Journal of biological chemistry 20091030
Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. The Journal of neuroscience : the official journal of the Society for Neuroscience 20091014
Comparison of chemical binding to recombinant fathead minnow and human estrogen receptors alpha in whole cell and cell-free binding assays. Environmental toxicology and chemistry 20091001
Interactions between neuroactive steroids and reelin haploinsufficiency in Purkinje cell survival. Neurobiology of disease 20091001
CRK7 modifies the MAPK pathway and influences the response to endocrine therapy. Carcinogenesis 20091001
Early regulation of brain aromatase (cyp19a1b) by estrogen receptors during zebrafish development. Developmental dynamics : an official publication of the American Association of Anatomists 20091001
Activity of fulvestrant 500 mg versus anastrozole 1 mg as first-line treatment for advanced breast cancer: results from the FIRST study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920
[Fulvestrant in heavily pretreated postmenopausal women with advanced breast cancer]. Medicina clinica 20090919
Induction of cells differentiation and ABC transporters expression by a myco-estrogen, zearalenone, in human choriocarcinoma cell line (BeWo). Toxicology 20090919
Activity of fulvestrant versus exemestane in advanced breast cancer patients with or without visceral metastases: data from the EFECT trial. Breast cancer research and treatment 20090901
Prospective assessment of the endometrium in postmenopausal breast cancer patients treated with fulvestrant. Breast cancer research and treatment 20090901
Cost-utility analysis for advanced breast cancer therapy in Germany: results of the fulvestrant sequencing model. Breast cancer research and treatment 20090901
Estrogen regulation of thrombospondin-1 in human breast cancer cells. International journal of cancer 20090901
Resistance to antiestrogen arzoxifene is mediated by overexpression of cyclin D1. Molecular endocrinology (Baltimore, Md.) 20090901
Effect of ellagic acid on the expression of human telomerase reverse transcriptase (hTERT) alpha+beta+ transcript in estrogen receptor-positive MCF-7 breast cancer cells. Clinical biochemistry 20090901
Estrogen can signal through multiple pathways to regulate oocyte cyst breakdown and primordial follicle assembly in the neonatal mouse ovary. The Journal of endocrinology 20090901
Differential effects of steroids on the synthesis of polyunsaturated fatty acids by human neuroblastoma cells. Neurochemistry international 20090901
Repression of ESR1 through actions of estrogen receptor alpha and Sin3A at the proximal promoter. Molecular and cellular biology 20090901
HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease. Annals of the New York Academy of Sciences 20090901
Long-term potentiation in the rat medial vestibular nuclei depends on locally synthesized 17beta-estradiol. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090826
Characterization of the weak estrogen receptor alpha agonistic activity of exemestane. Breast cancer research and treatment 20090801
Cholesterol-promoted synaptogenesis requires the conversion of cholesterol to estradiol in the hippocampus. Hippocampus 20090801
Blockade of estrogen action upregulates estrogen receptor-alpha mRNA in the fetal brain. Neonatology 20090801
Estrogen rapidly activates the PI3K/AKT pathway and hypoxia-inducible factor 1 and induces vascular endothelial growth factor A expression in luminal epithelial cells of the rat uterus. Biology of reproduction 20090801
Androgen- and estrogen-independent regulation of copulatory behavior following castration in male B6D2F1 mice. Hormones and behavior 20090801
In vitro exposure to xenoestrogens induces growth hormone transcription and release via estrogen receptor-dependent pathways in rat pituitary GH3 cells. Steroids 20090801
A novel mechanism of natural vitamin E tocotrienol activity: involvement of ERbeta signal transduction. American journal of physiology. Endocrinology and metabolism 20090801
Direct chronic effect of steroid hormones in attenuating uterine arterial myogenic tone: role of protein kinase c/extracellular signal-regulated kinase 1/2. Hypertension (Dallas, Tex. : 1979) 20090801
Fulvestrant treatment is associated with cholesterol plasma level reduction in hormone-receptor-positive metastatic breast cancer patients. Cancer biology & therapy 20090801
The clinical relevance of endocrine-therapy-induced changes in lipid metabolism in breast cancer patients. Cancer biology & therapy 20090801
Activation function 2 mediates dioxin-induced recruitment of estrogen receptor alpha to CYP1A1 and CYP1B1. Biochemical and biophysical research communications 20090724
Multiple mechanisms of soy isoflavones against oxidative stress-induced endothelium injury. Free radical biology & medicine 20090715
Positive feedback activation of estrogen receptors by the CXCL12-CXCR4 pathway. Cancer research 20090715
A yeast assay based on the gilthead sea bream (teleost fish) estrogen receptor beta for monitoring estrogen mimics. Ecotoxicology and environmental safety 20090701
Effects of 17beta-oestradiol on rat detrusor smooth muscle contractility. Experimental physiology 20090701
Oestrogen inhibits human colonic motility by a non-genomic cell membrane receptor-dependent mechanism. The British journal of surgery 20090701
Oestradiol decreases colonic permeability through oestrogen receptor beta-mediated up-regulation of occludin and junctional adhesion molecule-A in epithelial cells. The Journal of physiology 20090701
Beta3-tubulin is induced by estradiol in human breast carcinoma cells through an estrogen-receptor dependent pathway. Cell motility and the cytoskeleton 20090701
Structure-activity relationships of resveratrol and derivatives in breast cancer cells. Molecular nutrition & food research 20090701
Low doses of bisphenol A promote human seminoma cell proliferation by activating PKA and PKG via a membrane G-protein-coupled estrogen receptor. Environmental health perspectives 20090701
Diarylheptanoid phytoestrogens isolated from the medicinal plant Curcuma comosa: biologic actions in vitro and in vivo indicate estrogen receptor-dependent mechanisms. Environmental health perspectives 20090701
Phytoestrogens regulate mRNA and protein levels of guanine nucleotide-binding protein, beta-1 subunit (GNB1) in MCF-7 cells. Journal of cellular physiology 20090601
Essential role of the 90-kilodalton heat shock protein in mediating nongenomic estrogen signaling in coronary artery smooth muscle. The Journal of pharmacology and experimental therapeutics 20090601
Estrogen receptor alpha (ERalpha) mediates stimulatory effects of estrogen on aromatase (CYP19) gene expression in human placenta. Molecular endocrinology (Baltimore, Md.) 20090601
Cell death mechanisms in GT1-7 GnRH cells exposed to polychlorinated biphenyls PCB74, PCB118, and PCB153. Toxicology and applied pharmacology 20090601
[Fulvestrant use in clinical practice in France: a pharmacoepidemiologic study]. Bulletin du cancer 20090601
Bone turnover markers in postmenopausal breast cancer treated with fulvestrant--a pilot study. Breast (Edinburgh, Scotland) 20090601
Differential effects of aromatase inhibitors and antiestrogens on estrogen receptor expression in breast cancer cells. Anticancer research 20090601
ChIP-Seq of ERalpha and RNA polymerase II defines genes differentially responding to ligands. The EMBO journal 20090520
Loss of Phosphatase and Tensin homologue deleted on chromosome 10 engages ErbB3 and insulin-like growth factor-I receptor signaling to promote antiestrogen resistance in breast cancer. Cancer research 20090515
The Austrian fulvestrant registry: results from a prospective observation of fulvestrant in postmenopausal patients with metastatic breast cancer. Breast cancer research and treatment 20090501
Fulvestrant for systemic therapy of locally advanced or metastatic breast cancer in postmenopausal women: a systematic review. Breast cancer research and treatment 20090501
Mechanisms of resistance to structurally diverse antiestrogens differ under premenopausal and postmenopausal conditions: evidence from in vitro breast cancer cell models. Endocrinology 20090501
A phase II study of fulvestrant in the treatment of multiply-recurrent epithelial ovarian cancer. Gynecologic oncology 20090501
Estradiol downregulates miR-21 expression and increases miR-21 target gene expression in MCF-7 breast cancer cells. Nucleic acids research 20090501
Sex differences and central protective effect of 17beta-estradiol in the development of aldosterone/NaCl-induced hypertension. American journal of physiology. Heart and circulatory physiology 20090501
17beta-Estradiol-induced enhancement of estrogen receptor biosynthesis via MAPK pathway in mouse skeletal muscle myoblasts. The journal of physiological sciences : JPS 20090501
High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1. International journal of oncology 20090501
Short-term prophylactic tamoxifen reduces the incidence of antiestrogen-resistant/estrogen receptor-positive/progesterone receptor-negative mammary tumors. Cancer prevention research (Philadelphia, Pa.) 20090501
Targeting tumors using estrogen receptor ligand conjugates. Current cancer drug targets 20090501
Relaxing effects of phytoestrogen alpha-zearalanol on rat thoracic aorta rings in vitro. The Chinese journal of physiology 20090430
Estrogens and human papilloma virus oncogenes regulate human ether-à-go-go-1 potassium channel expression. Cancer research 20090415
Pilot study of gefitinib and fulvestrant in the treatment of post-menopausal women with advanced non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands) 20090401
Nitric oxide sensitive-guanylyl cyclase subunit expression changes during estrous cycle in anterior pituitary glands. American journal of physiology. Endocrinology and metabolism 20090401
Estrogen receptors are involved in xenoestrogen induction of growth hormone in the rat pituitary gland. The Journal of reproduction and development 20090401
Phase II trial of the farnesyltransferase inhibitor tipifarnib plus fulvestrant in hormone receptor-positive metastatic breast cancer: New York Cancer Consortium Trial P6205. Annals of oncology : official journal of the European Society for Medical Oncology 20090401
Growth-promoting effect of bisphenol A on neuroblastoma in vitro and in vivo. Journal of pediatric surgery 20090401
Gene expression profiling in Ishikawa cells: a fingerprint for estrogen active compounds. Toxicology and applied pharmacology 20090401
Oestrogenic regulation and differential expression of WNT4 in the bonnet monkey and rodent epididymis. Reproductive biomedicine online 20090401
Estrogen and TCDD influence RLN2 gene activity in estrogen receptor-positive human breast cancer cells. Annals of the New York Academy of Sciences 20090401
Activation of the unliganded estrogen receptor by prolactin in breast cancer cells. Oncogene 20090312
Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant. Breast cancer research and treatment 20090301
Point:Counterpoint: Estrogen and sex do/do not influence post-exercise indexes of muscle damage, inflammation, and repair. Journal of applied physiology (Bethesda, Md. : 1985) 20090301
A potential role for caveolin-1 in estradiol-17beta-induced proliferation of mouse embryonic stem cells: involvement of Src, PI3K/Akt, and MAPKs pathways. The international journal of biochemistry & cell biology 20090301
Involvement of estradiol-17beta and its membrane receptor, G protein coupled receptor 30 (GPR30) in regulation of oocyte maturation in zebrafish, Danio rario. General and comparative endocrinology 20090301
Blockade of estrogen receptor signaling inhibits growth and migration of medulloblastoma. Endocrinology 20090301
Enhanced expression of ERalpha in astrocytes modifies the response of cortical neurons to beta-amyloid toxicity. Neurobiology of disease 20090301
Involvement of G protein-coupled receptor 30 (GPR30) in rapid action of estrogen in primate LHRH neurons. Molecular endocrinology (Baltimore, Md.) 20090301
Use of global gene expression patterns in mechanistic studies of oestrogen action in MCF7 human breast cancer cells. The Journal of steroid biochemistry and molecular biology 20090301
Effects of CH4893237, a new orally active estrogen receptor downregulator, on breast cancer xenograft models with low serum estrogen levels. Oncology reports 20090301
Nebivolol decreases endothelial cell stiffness via the estrogen receptor beta: a nano-imaging study. Journal of hypertension 20090301
Gene network signaling in hormone responsiveness modifies apoptosis and autophagy in breast cancer cells. The Journal of steroid biochemistry and molecular biology 20090301
Effect of fluorination on the pharmacological profile of 11beta isomers of fulvestrant in breast carcinoma cells. Journal of medicinal chemistry 20090212
Signal pathway of 17beta-estradiol-induced MUC5B expression in human airway epithelial cells. American journal of respiratory cell and molecular biology 20090201
Identification of TACC1, NOV, and PTTG1 as new candidate genes associated with endocrine therapy resistance in breast cancer. Journal of molecular endocrinology 20090201
A cyp19a1b-gfp (aromatase B) transgenic zebrafish line that expresses GFP in radial glial cells. Genesis (New York, N.Y. : 2000) 20090201
Androgen-induced human breast cancer cell proliferation is mediated by discrete mechanisms in estrogen receptor-alpha-positive and -negative breast cancer cells. The Journal of steroid biochemistry and molecular biology 20090201
Rapid estrogen receptor-alpha activation improves ischemic tolerance in aged female rats through a novel protein kinase C epsilon-dependent mechanism. Endocrinology 20090201
Endocrine therapy for the treatment of postmenopausal women with breast cancer. Expert review of anticancer therapy 20090201
Bisphenol A at low nanomolar doses confers chemoresistance in estrogen receptor-alpha-positive and -negative breast cancer cells. Environmental health perspectives 20090201
Estradiol attenuates EGF-induced rapid uPAR mobilization and cell migration via the G-protein-coupled receptor 30 in ovarian cancer cells. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090201
Comparative effects of raloxifene, tamoxifen and estradiol on human osteoblasts in vitro: estrogen receptor dependent or independent pathways of raloxifene. The Journal of steroid biochemistry and molecular biology 20090201
Effects of cadmium on estrogen receptor mediated signaling and estrogen induced DNA synthesis in T47D human breast cancer cells. Toxicology letters 20090130
Estrogen attenuates left ventricular and cardiomyocyte hypertrophy by an estrogen receptor-dependent pathway that increases calcineurin degradation. Circulation research 20090130
Resting intracellular calcium concentration, depolarizing Gamma-Aminobutyric Acid and possible role of local estradiol synthesis in the developing male and female hippocampus. Neuroscience 20090123
Genotoxic and endocrine activities of bis(hydroxyphenyl)methane (bisphenol F) and its derivatives in the HepG2 cell line. Toxicology 20090108
Tamoxifen-induced [Ca2+]i rise and apoptosis in corneal epithelial cells. Toxicology 20090108
Enantioselective estrogenicity of o,p'-dichlorodiphenyltrichloroethane in the MCF-7 human breast carcinoma cell line. Environmental toxicology and chemistry 20090101
Monitoring of hormonal drug effect in a single breast cancer cell using an estrogen responsive GFP reporter vector delivered by a nanoneedle. Biosensors & bioelectronics 20090101
A bipartite recombinant yeast system for the identification of subtype-selective estrogen receptor ligands. Molecular biotechnology 20090101
Increased SULT1E1 activity in HepG2 hepatocytes decreases growth hormone stimulation of STAT5b phosphorylation. Steroids 20090101
Potential use of an estrogen-glucocorticoid receptor chimera as a drug screen for tissue selective estrogenic activity. Bone 20090101
Effects of 17beta-estradiol on rat urinary bladder: gender differences in anoxia-glucopenia and reperfusion damage. Neurourology and urodynamics 20090101
Estradiol promotes pituitary cell proliferation and gonadotroph differentiation at different doses and with different mechanisms in chick embryo. Steroids 20090101
Autocrine regulation of cell proliferation by estrogen receptor-alpha in estrogen receptor-alpha-positive breast cancer cell lines. BMC cancer 20090101
Cellular and regional distributions of ubiquitin-proteasome and endocytotic pathway components in the epithelium of rat efferent ductules and initial segment of the epididymis. Journal of andrology 20090101
Estrogenic effects of herbal medicines from Costa Rica used for the management of menopausal symptoms. Menopause (New York, N.Y.) 20090101
Fulvestrant in advanced breast cancer following tamoxifen and aromatase inhibition: a single center experience. The breast journal 20090101
Estrogen-induced stromal cell-derived factor-1 (SDF-1/Cxcl12) expression is repressed by progesterone and by Selective Estrogen Receptor Modulators via estrogen receptor alpha in rat uterine cells and tissues. Steroids 20090101
Effects of fulvestrant, an estrogen receptor antagonist, on MMQ cells and its mechanism. Neuro endocrinology letters 20090101
Pathologic and biologic response to preoperative endocrine therapy in patients with ER-positive ductal carcinoma in situ. BMC cancer 20090101
Recent advances in systemic therapy. When HER2 is not the target: advances in the treatment of HER2-negative metastatic breast cancer. Breast cancer research : BCR 20090101
Estrogen/estrogen receptor alpha signaling in mouse posterofrontal cranial suture fusion. PloS one 20090101
Treatment with the specific estrogen receptor antagonist ICI 182,780 demasculinizes neuron soma size in the developing zebra finch brain. Brain research 20081230
Economic evaluation of fulvestrant as an extra step in the treatment sequence for ER-positive advanced breast cancer. British journal of cancer 20081209
Premarin can act via estrogen receptors to rescue mice from heatstroke-induced lethality. Shock (Augusta, Ga.) 20081201
Laccase treatment impairs bisphenol A-induced cancer cell proliferation affecting estrogen receptor alpha-dependent rapid signals. IUBMB life 20081201
17-Beta-estradiol inhibits transforming growth factor-beta signaling and function in breast cancer cells via activation of extracellular signal-regulated kinase through the G protein-coupled receptor 30. Molecular pharmacology 20081201
ERBB2 influences the subcellular localization of the estrogen receptor in tamoxifen-resistant MCF-7 cells leading to the activation of AKT and RPS6KA2. Endocrine-related cancer 20081201
The influence of endocrine treatments for breast cancer on health-related quality of life. Cancer treatment reviews 20081101
17beta-estradiol activates estrogen receptor beta-signalling and inhibits transient receptor potential vanilloid receptor 1 activation by capsaicin in adult rat nociceptor neurons. Endocrinology 20081101
In vivo profiling of estrogen receptor/specificity protein-dependent transactivation. Endocrinology 20081101
Effects of estrogen receptor alpha- and beta-selective substances in the metaphysis of the tibia and on serum parameters of bone and fat tissue metabolism of ovariectomized rats. Bone 20081101
Differential regulation of the inducible nitric oxide synthase gene by estrogen receptors 1 and 2. The Journal of endocrinology 20081101
Estrogen prevents intestinal inflammation after trauma-hemorrhage via downregulation of angiotensin II and angiotensin II subtype I receptor. American journal of physiology. Gastrointestinal and liver physiology 20081101
Ebenfurans IV-VIII from Onobrychis ebenoides: evidence that C-prenylation is the key determinant of the cytotoxicity of 3-formyl-2-arylbenzofurans. Journal of natural products 20081101
Estrogens and genomic instability in human breast cancer cells--involvement of Src/Raf/Erk signaling in micronucleus formation by estrogenic chemicals. Carcinogenesis 20081001
Fispemifene [Z-2-{2-[4-(4-chloro-1,2-diphenylbut-1-enyl)-phenoxy]ethoxy}-ethanol], a novel selective estrogen receptor modulator, attenuates glandular inflammation in an animal model of chronic nonbacterial prostatitis. The Journal of pharmacology and experimental therapeutics 20081001
ICI 182,780 penetrates brain and hypothalamic tissue and has functional effects in the brain after systemic dosing. Endocrinology 20081001
Comparative effects of estradiol, methyl-piperidino-pyrazole, raloxifene, and ICI 182 780 on gene expression in the murine uterus. Journal of molecular endocrinology 20081001
Potential role of G-protein-coupled receptor 30 (GPR30) in estradiol-17beta-stimulated IGF-I mRNA expression in bovine satellite cell cultures. Domestic animal endocrinology 20081001
mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene-expression levels. Cancer science 20081001
Hormonal regulation of cardiac KCNE2 gene expression. Molecular and cellular endocrinology 20080924
Phase II study of fulvestrant (Faslodex) in castration resistant prostate cancer. The Prostate 20080915
Development of resistance to targeted therapies transforms the clinically associated molecular profile subtype of breast tumor xenografts. Cancer research 20080915
Resveratrol attenuates hepatic injury after trauma-hemorrhage via estrogen receptor-related pathway. Shock (Augusta, Ga.) 20080901
Regulation of ER alpha signaling pathway in neuronal HN10 cells: role of protein acetylation and Hsp90. Neurochemical research 20080901
Oestrogen receptors mediate oestrogen-induced increases in post-exercise rat skeletal muscle satellite cells. Acta physiologica (Oxford, England) 20080901
Oestrogen changed cardiomyocyte contraction and beta-adrenoceptor expression in rat hearts subjected to ischaemia-reperfusion. Experimental physiology 20080901
Effects of the antiestrogen fulvestrant (ICI 182,780) on gene expression of the rat efferent ductules. Biology of reproduction 20080901
Gender-specific protection of estrogen against gastric acid-induced duodenal injury: stimulation of duodenal mucosal bicarbonate secretion. Endocrinology 20080901
Crucial role of estrogen receptor-alpha interaction with transcription coregulators in follicle-stimulating hormone and transforming growth factor beta1 up-regulation of steroidogenesis in rat ovarian granulosa cells. Endocrinology 20080901
Ethanolic extract of Actaea racemosa (black cohosh) potentiates bone nodule formation in MC3T3-E1 preosteoblast cells. Bone 20080901
Central estrogen inhibition of angiotensin II-induced hypertension in male mice and the role of reactive oxygen species. American journal of physiology. Heart and circulatory physiology 20080901
Fulvestrant--a novel estrogen receptor antagonist for the treatment of advanced breast cancer. Drugs of today (Barcelona, Spain : 1998) 20080901
Estrogenic activity of environmental polycyclic aromatic hydrocarbons in uterus of immature Wistar rats. Toxicology letters 20080828
Inhibitory effects of genistein and resveratrol on guinea pig gallbladder contractility in vitro. World journal of gastroenterology 20080821
Broad modulation of neuropathic pain states by a selective estrogen receptor beta agonist. European journal of pharmacology 20080820
Expression of the estrogen receptor during differentiation of human osteoclasts. Steroids 20080801
The G protein-coupled receptor GPR30 inhibits human urothelial cell proliferation. Endocrinology 20080801
Effects of fulvestrant alone or combined with different steroids in human breast cancer cells in vitro. Climacteric : the journal of the International Menopause Society 20080801
Role of estrogen receptors and aromatase on brain protein synthesis rates in ovariectomized female rats fed genistein. Nutritional neuroscience 20080801
Pharmacokinetic profile of the fulvestrant loading dose regimen in postmenopausal women with hormone receptor-positive advanced breast cancer. Clinical breast cancer 20080801
The role of estrogen in the developmental appearance of sensory-motor behaviors in the zebrafish (Danio rerio): the characterization of the 'listless' model. Brain research 20080730
Raloxifene analogue LY117018 suppresses oxidative stress-induced endothelial cell apoptosis through activation of ERK1/2 signaling pathway. European journal of pharmacology 20080728
MCF-7aro/ERE, a novel cell line for rapid screening of aromatase inhibitors, ERalpha ligands and ERRalpha ligands. Biochemical pharmacology 20080715
Resveratrol stimulates nitric oxide production by increasing estrogen receptor alpha-Src-caveolin-1 interaction and phosphorylation in human umbilical vein endothelial cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080701
Estrogen receptor-alpha hinge-region lysines 302 and 303 regulate receptor degradation by the proteasome. Molecular endocrinology (Baltimore, Md.) 20080701
Roles of IGF-I and the estrogen, androgen and IGF-I receptors in estradiol-17beta- and trenbolone acetate-stimulated proliferation of cultured bovine satellite cells. Domestic animal endocrinology 20080701
Activation of estrogen receptor is crucial for resveratrol-stimulating muscular glucose uptake via both insulin-dependent and -independent pathways. Diabetes 20080701
Estradiol abolishes reduction in cell death by the opioid agonist Met5-enkephalin after oxygen glucose deprivation in isolated cardiomyocytes from both sexes. American journal of physiology. Heart and circulatory physiology 20080701
Apigenin inhibits antiestrogen-resistant breast cancer cell growth through estrogen receptor-alpha-dependent and estrogen receptor-alpha-independent mechanisms. Molecular cancer therapeutics 20080701
Estrogen and the Ca2+-mobilizing agonist ATP evoke acute NO synthesis via distinct pathways in an individual human vascular endothelium-derived cell. American journal of physiology. Cell physiology 20080601
Combining fulvestrant (Faslodex) with continued oestrogen suppression in endocrine-sensitive advanced breast cancer: the SoFEA trial. Clinical oncology (Royal College of Radiologists (Great Britain)) 20080601
Octylphenol stimulates resistin gene expression in 3T3-L1 adipocytes via the estrogen receptor and extracellular signal-regulated kinase pathways. American journal of physiology. Cell physiology 20080601
Genomic deletion of estrogen receptors ERalpha and ERbeta does not alter estrogen-mediated inhibition of Ca2+ influx and contraction in murine cardiomyocytes. American journal of physiology. Heart and circulatory physiology 20080601
Activation of estrogen receptor-alpha by the anion nitrite. Cancer research 20080515
Fulvestrant (Faslodex) in advanced breast cancer: clinical experience from a Belgian cooperative study. Breast cancer research and treatment 20080501
Estrogen receptor beta increases the efficacy of antiestrogens by effects on apoptosis and cell cycling in breast cancer cells. Breast cancer research and treatment 20080501
Tenascin is highly expressed in endometriosis and its expression is upregulated by estrogen. Fertility and sterility 20080501
Effects of 17beta-estradiol on neuronal cell excitability and neurotransmission in the suprachiasmatic nucleus of rat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20080501
Genistein and daidzein induced apoA-1 transactivation in hepG2 cells expressing oestrogen receptor-alpha. The British journal of nutrition 20080501
Estrogen determines sex differences in airway responsiveness after allergen exposure. American journal of respiratory cell and molecular biology 20080501
Suppression of NO production and 8-nitroguanosine formation by phenol-containing endocrine-disrupting chemicals in LPS-stimulated macrophages: involvement of estrogen receptor-dependent or -independent pathways. Nitric oxide : biology and chemistry 20080501
Relaxin (RLX) and estrogen affect estrogen receptor alpha, vascular endothelial growth factor, and RLX receptor expression in the neonatal porcine uterus and cervix. Reproduction (Cambridge, England) 20080501
Fulvestrant (Faslodex), an estrogen selective receptor downregulator, in therapy of women with systemic lupus erythematosus. clinical, serologic, bone density, and T cell activation marker studies: a double-blind placebo-controlled trial. The Journal of rheumatology 20080501
Combination of anastrozole with fulvestrant in the intratumoral aromatase xenograft model. Cancer research 20080501
Hormone therapy for breast cancer, with an emphasis on the pure antiestrogen fulvestrant: mode of action, antitumor efficacy and effects on bone health. Expert opinion on drug safety 20080501
Estrogenic phenol and catechol metabolites of PCBs modulate catechol-O-methyltransferase expression via the estrogen receptor: potential contribution to cancer risk. Current drug metabolism 20080501
Gene expression profiles in breast cancer to identify estrogen receptor target genes. Mini reviews in medicinal chemistry 20080501
Contribution of alpha2-adrenoceptors to the mitogenic effect of catecholestrogen in human breast cancer MCF-7 cells. The Journal of steroid biochemistry and molecular biology 20080501
The type I insulin-like growth factor receptor pathway: a key player in cancer therapeutic resistance. Frontiers in bioscience : a journal and virtual library 20080501
Fulvestrant in heavily pretreated metastatic breast cancer: is it still effective as a very advanced line of treatment? The Israel Medical Association journal : IMAJ 20080501
Genistein potentiates protein kinase A activity in porcine coronary artery. Molecular and cellular biochemistry 20080401
Analysis of the effects of oestrogen receptor alpha (ERalpha)- and ERbeta-selective ligands given in combination to ovariectomized rats. British journal of pharmacology 20080401
The specific estrogen receptor antagonist ICI 182,780 masculinizes development of the zebra finch syrinx. General and comparative endocrinology 20080401
Understanding the data, meeting patients' needs. Breast (Edinburgh, Scotland) 20080401
Double-blind, randomized placebo controlled trial of fulvestrant compared with exemestane after prior nonsteroidal aromatase inhibitor therapy in postmenopausal women with hormone receptor-positive, advanced breast cancer: results from EFECT. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. Chemical research in toxicology 20080401
Mitogen activated protein kinase (MAPK) mediates non-genomic pathway of estrogen on T cell cytokine production following trauma-hemorrhage. Cytokine 20080401
Fulvestrant: expanding the endocrine treatment options for patients with hormone receptor-positive advanced breast cancer. Breast (Edinburgh, Scotland) 20080401
GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat. The European journal of neuroscience 20080401
Estrogen regulates the localization and expression of calbindin-D9k in the pituitary gland of immature male rats via the ERalpha-pathway. Molecular and cellular endocrinology 20080326
Estrogen induces estrogen-related receptor alpha gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells. The Journal of biological chemistry 20080314
Transactivation of ERalpha by Rosiglitazone induces proliferation in breast cancer cells. Breast cancer research and treatment 20080301
17alpha-Estradiol is neuroprotective in male and female rats in a model of early brain injury. Experimental neurology 20080301
4-Alkylphenols and related chemicals show similar effect on the function of human and rat estrogen receptor alpha in reporter gene assay. Chemosphere 20080301
Estradiol stimulates transcription of nuclear respiratory factor-1 and increases mitochondrial biogenesis. Molecular endocrinology (Baltimore, Md.) 20080301
Rapid action of estrogens on intracellular calcium oscillations in primate luteinizing hormone-releasing hormone-1 neurons. Endocrinology 20080301
The contributions of oestrogen receptor isoforms to the development of papillary and anaplastic thyroid carcinomas. The Journal of pathology 20080301
Genistein, a plant-derived isoflavone, counteracts the antilipolytic action of insulin in isolated rat adipocytes. The Journal of steroid biochemistry and molecular biology 20080301
ABCC11 expression is regulated by estrogen in MCF7 cells, correlated with estrogen receptor alpha expression in postmenopausal breast tumors and overexpressed in tamoxifen-resistant breast cancer cells. Endocrine-related cancer 20080301
Effects of thyroid hormones on human breast cancer cell proliferation. The Journal of steroid biochemistry and molecular biology 20080301
Role of the insulin-like growth factor system on an estrogen-dependent cancer phenotype in the MCF-7 human breast cancer cell line. The Journal of steroid biochemistry and molecular biology 20080301
Induction of regulatory T cells by physiological level estrogen. Journal of cellular physiology 20080201
Hormonal regulation of BCRP expression in human placental BeWo cells. Pharmaceutical research 20080201
Estrogen-enhanced gene expression of lipoprotein lipase in heart is antagonized by progesterone. Endocrinology 20080201
Human prolactin gene promoter regulation by estrogen: convergence with tumor necrosis factor-alpha signaling. Endocrinology 20080201
Effects of fulvestrant 750mg in premenopausal women with oestrogen-receptor-positive primary breast cancer. European journal of cancer (Oxford, England : 1990) 20080201
Soy isoflavones decrease the catechol-O-methyltransferase-mediated inactivation of 4-hydroxyestradiol in cultured MCF-7 cells. Carcinogenesis 20080201
Xenoestrogens modulate vascular endothelial growth factor secretion in breast cancer cells through an estrogen receptor-dependent mechanism. The Journal of endocrinology 20080201
Estradiol, tamoxifen and ICI 182,780 alter alpha3 and beta1 integrin expression and laminin-1 adhesion in oral squamous cell carcinoma cell cultures. Oral oncology 20080101
Estrogen induces endothelial progenitor cells proliferation and migration by estrogen receptors and PI3K-dependent pathways. Microvascular research 20080101
Comparison of the estrogenic potencies of standardized soy extracts by immature rat uterotrophic bioassay. Phytomedicine : international journal of phytotherapy and phytopharmacology 20080101
27-hydroxycholesterol is an endogenous selective estrogen receptor modulator. Molecular endocrinology (Baltimore, Md.) 20080101
Blockade of estrogen receptors decreases CNS and pituitary prostaglandin synthase expression in fetal sheep. Neuroendocrinology 20080101
Ginsenoside Rg1 exerts estrogen-like activities via ligand-independent activation of ERalpha pathway. The Journal of steroid biochemistry and molecular biology 20080101
Topical fulvestrant solution has no effect on male and postmenopausal female androgenetic alopecia: results from two randomized, proof-of-concept studies. The British journal of dermatology 20080101
The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells. Reproductive toxicology (Elmsford, N.Y.) 20080101
Differential expression of microRNAs in myometrium and leiomyomas and regulation by ovarian steroids. Journal of cellular and molecular medicine 20080101
Inhibition of vascular inflammation by dehydroepiandrosterone sulfate in human aortic endothelial cells: roles of PPARalpha and NF-kappaB. Vascular pharmacology 20080101
[Research on phytoestrogenic effects and its mechanism of psoralen]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080101
Pancreatic insulin content regulation by the estrogen receptor ER alpha. PloS one 20080101
Role of estrogens and their receptors in adhesion and invasiveness of breast cancer cells. Advances in experimental medicine and biology 20080101
Phytoestrogens modulate the expression of 17alpha-estradiol metabolizing enzymes in cultured MCF-7 cells. Advances in experimental medicine and biology 20080101
Diethylstilbestrol-induced estrogen receptor-dependent [Ca2+]i rises and apoptosis in Chinese hamster ovary (CHO) cells. Journal of receptor and signal transduction research 20080101
Estrogen receptor beta displays cell cycle-dependent expression and regulates the G1 phase through a non-genomic mechanism in prostate carcinoma cells. Cellular oncology : the official journal of the International Society for Cellular Oncology 20080101
The effect of long-term resveratrol treatment on relaxation to estrogen in aortae from male and female rats: role of nitric oxide and superoxide. Vascular pharmacology 20080101
17Beta-estradiol prevents retinal ganglion cell loss induced by acute rise of intraocular pressure in rat. Progress in brain research 20080101
Phytoestrogens induce differential estrogen receptor beta-mediated responses in transfected MG-63 cells. Endocrine 20080101
Two estrogen response element sequences near the PCNA gene are not responsible for its estrogen-enhanced expression in MCF7 cells. PloS one 20080101
The use of fulvestrant, a parenteral endocrine agent, in intestinal obstruction due to metastatic lobular breast carcinoma. World journal of surgical oncology 20080101
Molecular imaging provides novel insights on estrogen receptor activity in mouse brain. Molecular imaging 20080101
Distribution plasticity of the human estrogen receptor alpha in live cells: distinct imaging of consecutively expressed receptors. Journal of molecular biology 20071214
Synthesis and evaluation of the antiproliferative activities of derivatives of carboxyalkyl isoflavones linked to N-t-Boc-hexylenediamine. Journal of medicinal chemistry 20071213
A novel dual-target steroid sulfatase inhibitor and antiestrogen: SR 16157, a promising agent for the therapy of breast cancer. Breast cancer research and treatment 20071201
Mechanism involved in genistein activation of insulin-like growth factor 1 receptor expression in human breast cancer cells. The British journal of nutrition 20071201
Resveratrol enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via ER-dependent ERK1/2 activation. Phytomedicine : international journal of phytotherapy and phytopharmacology 20071201
Vasorelaxant action of 17 -estradiol in rat uterine arteries: role of nitric oxide synthases and estrogen receptors. American journal of physiology. Heart and circulatory physiology 20071201
Ethanol-induced ligand-independent activation of ERalpha mediated by cyclic AMP/PKA signaling pathway: an in vitro study on MCF-7 breast cancer cells. International journal of oncology 20071201
Anti-estrogenic actions of histone deacetylase inhibitors in MCF-7 breast cancer cells. Endocrine-related cancer 20071201
Reversal of the estrogen receptor negative phenotype in breast cancer and restoration of antiestrogen response. Clinical cancer research : an official journal of the American Association for Cancer Research 20071201
Cks1 regulates cdk1 expression: a novel role during mitotic entry in breast cancer cells. Cancer research 20071201
Differential regulation of cyclic AMP synthesis by estrogen in MCF7 cells. Biochemical and biophysical research communications 20071123
Estrogen receptors in BRCA1-mutant breast cancer: now you see them, now you don't. Journal of the National Cancer Institute 20071121
Molecular basis for estrogen receptor alpha deficiency in BRCA1-linked breast cancer. Journal of the National Cancer Institute 20071121
Fulvestrant in heavily pre-treated patients with advanced breast cancer: results from a single compassionate use programme centre. Breast cancer research and treatment 20071101
Fulvestrant ('Faslodex') in heavily pretreated postmenopausal patients with advanced breast cancer: single centre clinical experience from the compassionate use programme. Breast cancer research and treatment 20071101
Influence of estrogen and xenoestrogens on basolateral uptake of tetraethylammonium by opossum kidney cells in culture. The Journal of pharmacology and experimental therapeutics 20071101
Dynamic regulation of estrogen receptor-alpha isoform expression in the mouse fallopian tube: mechanistic insight into estrogen-dependent production and secretion of insulin-like growth factors. American journal of physiology. Endocrinology and metabolism 20071101
Subtype-specific activation of estrogen receptors by a special extract of Rheum rhaponticum (ERr 731), its aglycones and structurally related compounds in U2OS human osteosarcoma cells. Phytomedicine : international journal of phytotherapy and phytopharmacology 20071101
Expression and role of estrogen receptor alpha and beta in medullary thyroid carcinoma: different roles in cancer growth and apoptosis. The Journal of endocrinology 20071101
Induction of cell death in antiestrogen resistant human breast cancer cells by the protein kinase CK2 inhibitor DMAT. Cancer letters 20071028
Functional characterization of estrogen receptor subtypes, ERalpha and ERbeta, mediating vitellogenin production in the liver of rainbow trout. Toxicology and applied pharmacology 20071015
Neonatal porcine endometrial development and epithelial proliferation affected by age and exposure to estrogen and relaxin. Domestic animal endocrinology 20071001
Progesterone, but not luteal estrogen, is required for the establishment of pregnancy in the new world monkey Cebus apella. American journal of primatology 20071001
Resveratrol-induced inhibition of insulin secretion from rat pancreatic islets: evidence for pivotal role of metabolic disturbances. American journal of physiology. Endocrinology and metabolism 20071001
Increased level of cellular Bip critically determines estrogenic potency for a xenoestrogen kepone in the mouse uterus. Endocrinology 20071001
Human CYP2A6 is induced by estrogen via estrogen receptor. Drug metabolism and disposition: the biological fate of chemicals 20071001
Mechanism of estrogen-mediated attenuation of hepatic injury following trauma-hemorrhage: Akt-dependent HO-1 up-regulation. Journal of leukocyte biology 20071001
Peripheral estrogen receptor-alpha selectively modulates the waveform of GH secretory bursts in healthy women. American journal of physiology. Regulatory, integrative and comparative physiology 20071001
Regulation of C-C motif chemokine ligand 2 and its receptor in human decidual stromal cells by pregnancy-associated hormones in early gestation. Human reproduction (Oxford, England) 20071001
17Beta-oestradiol partially attenuates the inhibition of nitric oxide synthase-3 by advanced glycation end-products in human platelets. Clinical and experimental pharmacology & physiology 20071001
Delayed and persistent ERK1/2 activation is required for 4-hydroxytamoxifen-induced cell death. Steroids 20071001
Oestrogen and progesterone reduce lipopolysaccharide-induced expression of tumour necrosis factor-alpha and interleukin-18 in midbrain astrocytes. Journal of neuroendocrinology 20071001
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nature medicine 20071001
[Systemic therapy of male breast cancer]. Zentralblatt fur Chirurgie 20071001
Definition of functionally important mechanistic differences among selective estrogen receptor down-regulators. Cancer research 20071001
The cooked meat derived genotoxic carcinogen 2-amino-3-methylimidazo[4,5-b]pyridine has potent hormone-like activity: mechanistic support for a role in breast cancer. Cancer research 20071001
Polychlorinated biphenyls alter the expression of endothelial nitric oxide synthase mRNA in human umbilical vein endothelial cells. Human & experimental toxicology 20071001
Tamoxifen stimulates calcium entry into human platelets. Journal of cardiovascular pharmacology 20071001
A novel molecular assay to discriminate transcriptional effects caused by xenoestrogens. Molecular and cellular endocrinology 20070930
Potentiation of ICI182,780 (Fulvestrant)-induced estrogen receptor-alpha degradation by the estrogen receptor-related receptor-alpha inverse agonist XCT790. The Journal of biological chemistry 20070928
Sex-dependent differences in the activity and modulation of N-methyl-d-aspartic acid receptors in rat dorsal root ganglia neurons. Neuroscience 20070921
Progestins reinitiate cell cycle progression in antiestrogen-arrested breast cancer cells through the B-isoform of progesterone receptor. Cancer research 20070915
Estrogen-mediated endothelial progenitor cell biology and kinetics for physiological postnatal vasculogenesis. Circulation research 20070914
[Antiestrogen treatment in postmenopausal patients with metastatic breast cancer]. Ugeskrift for laeger 20070910
Design, synthesis, and estrogenic activity of a novel estrogen receptor modulator--a hybrid structure of 17beta-estradiol and vitamin E in hippocampal neurons. Journal of medicinal chemistry 20070906
17Beta-estradiol protects depletion of rat temporal cortex somatostatinergic system by beta-amyloid. Neurobiology of aging 20070901
Estrogen receptor alpha (ERalpha) and insulin-like growth factor I receptor (IGF-IR) cross-talk in the gonadotropic alphaT3-1 cell line. Journal of cellular physiology 20070901
Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway. Journal of leukocyte biology 20070901
Ginsenoside Rb1 inhibits tube-like structure formation of endothelial cells by regulating pigment epithelium-derived factor through the oestrogen beta receptor. British journal of pharmacology 20070901
Therapeutic concentrations of raloxifene augment nitric oxide-dependent coronary artery dilatation in vitro. British journal of pharmacology 20070901
Delay of postnatal maturation sensitizes the mouse prostate to testosterone-induced pronounced hyperplasia: protective role of estrogen receptor-beta. The American journal of pathology 20070901
Estrogen increases smooth muscle expression of alpha2C-adrenoceptors and cold-induced constriction of cutaneous arteries. American journal of physiology. Heart and circulatory physiology 20070901
Up-regulation of Per1 expression by estradiol and progesterone in the rat uterus. The Journal of endocrinology 20070901
A novel ligand-independent function of the estrogen receptor is essential for osteocyte and osteoblast mechanotransduction. The Journal of biological chemistry 20070831
Membrane estrogen receptor-alpha interactions with metabotropic glutamate receptor 1a modulate female sexual receptivity in rats. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070829
Loss of tumourigenicity of stably ERbeta-transfected MCF-7 breast cancer cells. Molecular and cellular endocrinology 20070815
Raloxifene increases proliferation of human endothelial cells in association with increased gene expression of cyclins A and B1. Fertility and sterility 20070801
Androgen receptor or estrogen receptor-beta blockade alters DHEA-, DHT-, and E(2)-induced proliferation and PSA production in human prostate cancer cells. The Prostate 20070801
A calcium-binding protein, calbindin-D9k, is regulated through an estrogen-receptor mediated mechanism following xenoestrogen exposure in the GH3 cell line. Toxicological sciences : an official journal of the Society of Toxicology 20070801
Estrogen-dependent regulation of Eg5 in breast cancer cells. Anti-cancer drugs 20070801
Her2 and progesterone receptor status are not predictive of response to fulvestrant treatment. Clinical cancer research : an official journal of the American Association for Cancer Research 20070801
Effect of nuclear export inhibition on estrogen receptor regulation in breast cancer cells. Journal of molecular endocrinology 20070801
Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling. Annals of oncology : official journal of the European Society for Medical Oncology 20070801
17beta-estradiol inhibits angiotensin II-induced collagen synthesis of cultured rat cardiac fibroblasts via modulating angiotensin II receptors. European journal of pharmacology 20070719
Forkhead proteins are critical for bone morphogenetic protein-2 regulation and anti-tumor activity of resveratrol. The Journal of biological chemistry 20070706
Demonstration of mitochondrial oestrogen receptor beta and oestrogen-induced attenuation of cytochrome c oxidase subunit I expression in human periodontal ligament cells. Archives of oral biology 20070701
Increase of carcinogenic risk via enhancement of cyclooxygenase-2 expression and hydroxyestradiol accumulation in human lung cells as a result of interaction between BaP and 17-beta estradiol. Carcinogenesis 20070701
Uterine TRPV6 expression during the estrous cycle and pregnancy in a mouse model. American journal of physiology. Endocrinology and metabolism 20070701
Estrogen inhibition of norepinephrine responsiveness is initiated at the plasma membrane of GnRH-producing GT1-7 cells. The Journal of endocrinology 20070701
Resveratrol inhibits rat aortic vascular smooth muscle cell proliferation via estrogen receptor dependent nitric oxide production. Journal of cardiovascular pharmacology 20070701
Fulvestrant (Faslodex) -- how to make a good drug better. The oncologist 20070701
Raloxifene acutely reduces glutamate-induced intracellular calcium increase in cultured rat cortical neurons via inhibition of high-voltage-activated calcium current. Neuroscience 20070629
Inhibition of apoptosis-regulated signaling kinase-1 and prevention of congestive heart failure by estrogen. Circulation 20070626
Interplay between the levels of estrogen and estrogen receptor controls the level of the granzyme inhibitor, proteinase inhibitor 9 and susceptibility to immune surveillance by natural killer cells. Oncogene 20070614
Estrogen modulates TNF-alpha-induced inflammatory responses in rat aortic smooth muscle cells through estrogen receptor-beta activation. American journal of physiology. Heart and circulatory physiology 20070601
Raloxifene inhibits transient outward and ultra-rapid delayed rectifier potassium currents in human atrial myocytes. European journal of pharmacology 20070601
Tetrabromodiphenyl ether (BDE 47) evokes estrogenicity and calbindin-D9k expression through an estrogen receptor-mediated pathway in the uterus of immature rats. Toxicological sciences : an official journal of the Society of Toxicology 20070601
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro. British journal of pharmacology 20070601
Urodynamic changes in a noble rat model for nonbacterial prostatic inflammation. The Prostate 20070601
The PI3K/Akt pathway mediates the nongenomic cardioprotective effects of estrogen following trauma-hemorrhage. Annals of surgery 20070601
The effects of synthetic 19-norprogestins on osteoblastic cell function are mediated by their non-phenolic reduced metabolites. The Journal of endocrinology 20070601
Estrogen receptor alpha mediates breast cancer cell resistance to paclitaxel through inhibition of apoptotic cell death. Cancer research 20070601
The pathway-selective estrogen receptor ligand WAY-169916 reduces infarct size after myocardial ischemia and reperfusion by an estrogen receptor dependent mechanism. Journal of cardiovascular pharmacology 20070601
Effects of a phytoestrogen-containing soy extract on the growth-inhibitory activity of ICI 182 780 in an experimental model of estrogen-dependent breast cancer. Endocrine-related cancer 20070601
Influence of estrogens and antiestrogens on the expression of selected hormone-responsive genes. Maturitas 20070520
The activation by estrogen receptor agonists of the BK(Ca)-channel in human cardiac fibroblasts. Biochemical pharmacology 20070501
An inhibitory effect on cell proliferation by blockage of the MAPK/estrogen receptor/MDM2 signal pathway in gynecologic cancer. Gynecologic oncology 20070501
Identification of a series of tetrahydroisoquinoline derivatives as potential therapeutic agents for breast cancer. Bioorganic & medicinal chemistry letters 20070501
Evidence for an estradiol-agonistic action of nebivolol in spontaneously hypertensive rats. Journal of hypertension 20070501
Effect of estrogen and inhibition of phosphatidylinositol-3 kinase on Akt and FOXO1 in rat uterus. Steroids 20070501
Classification of anti-estrogens according to intramolecular FRET effects on phospho-mutants of estrogen receptor alpha. Molecular cancer therapeutics 20070501
Evaluation of estrogenic/antiestrogenic activity of Onobrychis ebenoides extract - interaction with estrogen receptor subtypes ERalpha and ERbeta. Toxicology in vitro : an international journal published in association with BIBRA 20070401
Estrogen receptor-alpha mediates estrogen protection from angiotensin II-induced hypertension in conscious female mice. American journal of physiology. Heart and circulatory physiology 20070401
Expression of zebra fish aromatase cyp19a and cyp19b genes in response to the ligands of estrogen receptor and aryl hydrocarbon receptor. Toxicological sciences : an official journal of the Society of Toxicology 20070401
DNA content and chromatin texture of human breast epithelial cells transformed with 17-beta-estradiol and the estrogen antagonist ICI 182,780 as assessed by image analysis. Mutation research 20070401
Raloxifene and ICI182,780 increase estrogen receptor-alpha association with a nuclear compartment via overlapping sets of hydrophobic amino acids in activation function 2 helix 12. Molecular endocrinology (Baltimore, Md.) 20070401
Astrocyte-like cells as a main target for estrogen action during neuronal differentiation. Molecular and cellular neurosciences 20070401
Neuroprotection by estrogen against MPP+-induced dopamine neuron death is mediated by ERalpha in primary cultures of mouse mesencephalon. Experimental neurology 20070401
Neuroprotection by tamoxifen in focal cerebral ischemia is not mediated by an agonist action at estrogen receptors but is associated with antioxidant activity. Experimental neurology 20070401
Dehydroepiandrosterone improves murine osteoblast growth and bone tissue morphometry via mitogen-activated protein kinase signaling pathway independent of either androgen receptor or estrogen receptor. Journal of molecular endocrinology 20070401
Evaluation of fulvestrant in clinical practice: use of an electronic data registry. Clinical breast cancer 20070401
Synthesis, structure, and estrogenic activity of 4-amino-3-(2-methylbenzyl)coumarins on human breast carcinoma cells. Bioorganic & medicinal chemistry 20070315
Effect of genistein and raloxifene on vascular dependent platelet aggregation. Molecular and cellular endocrinology 20070315
Estradiol-induced conditioned place preference may require actions at estrogen receptors in the nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070301
SVEP1 expression is regulated in estrogen-dependent manner. Journal of cellular physiology 20070301
The antiestrogen tamoxifen activates BK channels and stimulates proliferation of MCF-7 breast cancer cells. Molecular pharmacology 20070301
Targeted salmon gene array (SalArray): a toxicogenomic tool for gene expression profiling of interactions between estrogen and aryl hydrocarbon receptor signalling pathways. Chemical research in toxicology 20070301
Estrogen receptor independent neurotoxic mechanism of bisphenol A, an environmental estrogen. Journal of veterinary science 20070301
Effects of genistein, resveratrol, and quercetin on steroidogenesis and proliferation of MA-10 mouse Leydig tumor cells. The Journal of endocrinology 20070301
Estrogen regulates Bcl-w and Bim expression: role in protection against beta-amyloid peptide-induced neuronal death. The Journal of neuroscience : the official journal of the Society for Neuroscience 20070207
Mechanisms of action of the carcinogenic heterocyclic amine PhIP. Toxicology letters 20070205
Modulation by phenylacetate of early estrogen-mediated events in MCF-7 breast cancer cells. Cancer chemotherapy and pharmacology 20070201
Paclitaxel induced apoptosis in breast cancer cells requires cell cycle transit but not Cdc2 activity. Cancer chemotherapy and pharmacology 20070201
Does estrogen contribute to the hepatic regeneration following portal branch ligation in rats? American journal of physiology. Gastrointestinal and liver physiology 20070201
17beta-Estradiol differentially regulates androgen-responsive genes through estrogen receptor-beta- and extracellular-signal regulated kinase-dependent pathways in LNCaP human prostate cancer cells. Molecular carcinogenesis 20070201
Neuroprotective effect of 17beta-estradiol against N-methyl-D-aspartate-induced retinal neurotoxicity via p-ERK induction. Journal of neuroscience research 20070201
Estrogen receptor-alpha mediates an intraovarian negative feedback loop on thecal cell steroidogenesis via modulation of Cyp17a1 (cytochrome P450, steroid 17alpha-hydroxylase/17,20 lyase) expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070201
Effects of 4-hydroxytamoxifen, raloxifene and ICI 182 780 on survival of uterine cancer cell lines in the presence and absence of exogenous estrogens. International journal of oncology 20070201
Role for HER2/neu and HER3 in fulvestrant-resistant breast cancer. International journal of oncology 20070201
Oestrogen receptor antagonist and hair regrowth in dogs with hair cycle arrest (alopecia X). Veterinary dermatology 20070201
Rapid modulation of long-term depression and spinogenesis via synaptic estrogen receptors in hippocampal principal neurons. Journal of neurochemistry 20070201
Modulation of the expression of bloom helicase by estrogenic agents. Biological & pharmaceutical bulletin 20070201
Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium. Cancer research 20070201
Cadmium induces mitogenic signaling in breast cancer cell by an ERalpha-dependent mechanism. Molecular and cellular endocrinology 20070129
Endothelium-independent relaxation to raloxifene in porcine coronary artery. European journal of pharmacology 20070126
Induction of uterine calbindin-D9k through an estrogen receptor-dependent pathway following single injection with xenobiotic agents in immature rats. Journal of toxicology and environmental health. Part A 20070115
Estradiol-17beta: tracing its metabolic significance in female fatbody of fifth instar larvae of silkworm, Bombyx mori L (race: Nistari). Life sciences 20070109
Estrogen stimulates the neuronal differentiation of human umbilical cord blood mesenchymal stem cells (CD34-). Neuroreport 20070108
Fulvestrant in advanced male breast cancer. Breast cancer research and treatment 20070101
In silico prediction of pregnane X receptor activators by machine learning approaches. Molecular pharmacology 20070101
Ligand-selective interdomain conformations of estrogen receptor-alpha. Molecular endocrinology (Baltimore, Md.) 20070101
Clinical benefit of fulvestrant in postmenopausal women with advanced breast cancer and primary or acquired resistance to aromatase inhibitors: final results of phase II Swiss Group for Clinical Cancer Research Trial (SAKK 21/00). Annals of oncology : official journal of the European Society for Medical Oncology 20070101
Estrogen receptor antagonist fulvestrant (ICI 182,780) inhibits the anti-inflammatory effect of glucocorticoids. Molecular pharmacology 20070101
Effects of fulvestrant 250mg in premenopausal women with oestrogen receptor-positive primary breast cancer. European journal of cancer (Oxford, England : 1990) 20070101
Effect of antiestrogens on EGF-mediated movement of human breast cancer cells. Pharmacology 20070101
Differential effects of centrally-administered oestrogen antagonist ICI-182,780 on oestrogen-sensitive functions in the hypothalamus. Journal of neuroendocrinology 20070101
Two unsuccessful clinical trials on endometriosis and a few lessons learned. Gynecologic and obstetric investigation 20070101
Oestrogen formation and connective tissue growth factor expression in rat granulosa cells. The Journal of endocrinology 20070101
Modulation of multidrug resistance gene expression in human breast cancer cells by (-)-gossypol-enriched cottonseed oil. Anticancer research 20070101
Evidence to implicate early modulation of interleukin-1beta expression in the neuroprotection afforded by 17beta-estradiol in male rats undergone transient middle cerebral artery occlusion. International review of neurobiology 20070101
Activation of estrogen receptor-beta by a special extract of Rheum rhaponticum (ERr 731), its aglycones and structurally related compounds. The Journal of steroid biochemistry and molecular biology 20070101
Determining the transrepression activity of xenoestrogen on nuclear factor-kappa B in Cos-1 cells by estrogen receptor-alpha. International journal of toxicology 20070101
Induction of acquired resistance to antiestrogen by reversible mitochondrial DNA depletion in breast cancer cell line. International journal of cancer 20070101
Mechanism of collagen biosynthesis up-regulation in cultured leiomyoma cells. Folia histochemica et cytobiologica 20070101
An estrogen receptor-beta agonist is active in models of inflammatory and chemical-induced pain. European journal of pharmacology 20061228
The expression of Hedgehog genes (Ihh, Dhh) and Hedgehog target genes (Ptc1, Gli1, Coup-TfII) is affected by estrogenic stimuli in the uterus of immature female rats. Toxicology and applied pharmacology 20061215
Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant. Cancer research 20061215
Hormonal activity of combinations of genistein, bisphenol A and 17beta-estradiol in the female Wistar rat. Archives of toxicology 20061201
Effects of estradiol on phenylephrine contractility associated with intracellular calcium release in rat aorta. American journal of physiology. Cell physiology 20061201
Raloxifene elicits combined rapid vasorelaxation and long-term anti-inflammatory actions in rat aorta. The Journal of pharmacology and experimental therapeutics 20061201
Estrogenic agonist activity of ICI 182,780 (Faslodex) in hippocampal neurons: implications for basic science understanding of estrogen signaling and development of estrogen modulators with a dual therapeutic profile. The Journal of pharmacology and experimental therapeutics 20061201
Ginsenoside Re, a main phytosterol of Panax ginseng, activates cardiac potassium channels via a nongenomic pathway of sex hormones. Molecular pharmacology 20061201
Estrogen produced in cultured hippocampal neurons is a functional regulator of a GABAergic machinery. Journal of neuroscience research 20061201
Inhibition of MLK3-MKK4/7-JNK1/2 pathway by Akt1 in exogenous estrogen-induced neuroprotection against transient global cerebral ischemia by a non-genomic mechanism in male rats. Journal of neurochemistry 20061201
Emerging principles for the development of resistance to antihormonal therapy: implications for the clinical utility of fulvestrant. The Journal of steroid biochemistry and molecular biology 20061201
Clinically occult cutaneous metastases. Journal of the American Academy of Dermatology 20061201
Aromatase and breast cancer. The Journal of steroid biochemistry and molecular biology 20061201
[Fulvestrant]. Deutsche medizinische Wochenschrift (1946) 20061201
Chronic exposure to fulvestrant promotes overexpression of the c-Met receptor in breast cancer cells: implications for tumour-stroma interactions. Endocrine-related cancer 20061201
Endocrine therapy resistance can be associated with high estrogen receptor alpha (ERalpha) expression and reduced ERalpha phosphorylation in breast cancer models. Endocrine-related cancer 20061201
Molecular cloning and characterization of the human WISP-2/CCN5 gene promoter reveal its upregulation by oestrogens. The Journal of endocrinology 20061201
Aromatase activity of human mesenchymal stem cells is stimulated by early differentiation, vitamin D and leptin. The Journal of endocrinology 20061201
Fulvestrant: a further treatment option for patients with metastatic uterine cancer? Onkologie 20061201
Endothelial cellular senescence is inhibited by nitric oxide: implications in atherosclerosis associated with menopause and diabetes. Proceedings of the National Academy of Sciences of the United States of America 20061107
Ovulation induction by antiestrogens in an Indian tropical vespertillionid bat, Scotophilus heathi. Life sciences 20061102
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of molecular graphics & modelling 20061101
The pure estrogen receptor antagonist ICI 182,780 promotes a novel interaction of estrogen receptor-alpha with the 3',5'-cyclic adenosine monophosphate response element-binding protein-binding protein/p300 coactivators. Molecular endocrinology (Baltimore, Md.) 20061101
Estrogen regulates epithelial cell deformability by modulation of cortical actomyosin through phosphorylation of nonmuscle myosin heavy-chain II-B filaments. Endocrinology 20061101
Estrogen modulates place learning through estrogen receptors in the hippocampus. Neurobiology of learning and memory 20061101
Cooperative effect of gefitinib and fumitremorgin c on cell growth and chemosensitivity in estrogen receptor alpha negative fulvestrant-resistant MCF-7 cells. International journal of oncology 20061101
Phytoestrogens regulate transcription and translation of vitamin D receptor in colon cancer cells. The Journal of endocrinology 20061101
The hop phytoestrogen, 8-prenylnaringenin, reverses the ovariectomy-induced rise in skin temperature in an animal model of menopausal hot flushes. The Journal of endocrinology 20061101
Effects of raloxifene on caveolin-1 mRNA and protein expressions in vascular smooth muscle cells. Acta biochimica et biophysica Sinica 20061101
Crosstalk between EGFR and extranuclear steroid receptors. Annals of the New York Academy of Sciences 20061101
Impact of 17beta-estradiol on cytokine-mediated apoptotic effects in primary hippocampal and neocortical cell cultures. Brain research 20061020
[Effects of ICI182780 (Faslodex) on proliferation and apoptosis induced by 17beta-estradiol in endometrial carcinoma cells]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20061018
Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein. Cancer research 20061015
Decreased chicken ovalbumin upstream promoter transcription factor II expression in tamoxifen-resistant breast cancer cells. Cancer research 20061015
Expression of Cystatin C in the rat endometrium during the peri-implantation period. Biochemical and biophysical research communications 20061013
Postmenopausal advanced breast cancer: options for therapy after tamoxifen and aromatase inhibitors. Breast (Edinburgh, Scotland) 20061001
2-methoxyestradiol inhibits differentiation and is cytotoxic to osteoclasts. Journal of cellular biochemistry 20061001
Flow cytometric cell cycle analysis allows for rapid screening of estrogenicity in MCF-7 breast cancer cells. Toxicology in vitro : an international journal published in association with BIBRA 20061001
Apoptotic and anti-proliferative effects of 17beta-estradiol and 17beta-estradiol-like compounds in the Hep3B cell line. Molecular and cellular biochemistry 20061001
Characterisation of the relaxant response to raloxifene in porcine coronary arteries. European journal of pharmacology 20060918
Hemodynamic effects of acute and repeated exposure to raloxifene in ovariectomized sheep. American journal of physiology. Heart and circulatory physiology 20060901
Molecular mechanism of inhibitory aryl hydrocarbon receptor-estrogen receptor/Sp1 cross talk in breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20060901
17 beta-estradiol modifies nitric oxide-sensitive guanylyl cyclase expression and down-regulates its activity in rat anterior pituitary gland. Endocrinology 20060901
Fulvestrant: pharmacologic profile versus existing endocrine agents for the treatment of breast cancer. The Annals of pharmacotherapy 20060901
Enhanced formation of non-phenolic androgen metabolites with intrinsic oestrogen-like gene transactivation potency in human breast cancer cells: a distinctive metabolic pattern. The Journal of endocrinology 20060901
Comparative gene expression profiling reveals partially overlapping but distinct genomic actions of different antiestrogens in human breast cancer cells. Journal of cellular biochemistry 20060801
Essiac and Flor-Essence herbal tonics stimulate the in vitro growth of human breast cancer cells. Breast cancer research and treatment 20060801
Distinct regulation by steroids of messenger RNAs for FSHR and CYP19A1 in bovine granulosa cells. Biology of reproduction 20060801
Estrogen regulation of the glucuronidation enzyme UGT2B15 in estrogen receptor-positive breast cancer cells. Endocrinology 20060801
Discovery of thiochroman derivatives bearing a carboxy-containing side chain as orally active pure antiestrogens. Bioorganic & medicinal chemistry letters 20060801
Estrogen-like activity and prevention effect of bone loss in calcium deficient ovariectomized rats by the extract of Pleurotus eryngii. Phytotherapy research : PTR 20060801
Insulin-like growth factor binding protein 2 is a marker for antiestrogen resistant human breast cancer cell lines but is not a major growth regulator. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20060801
Mechanisms underlying nebivolol-induced endothelial nitric oxide synthase activation in human umbilical vein endothelial cells. Clinical and experimental pharmacology & physiology 20060801
Time to response: comparison of fulvestrant and oral endocrine agents. Clinical breast cancer 20060801
[Estrogenicity of adzuki bean Phaseolus angularis wight. and its effect on proesterone receptor level in human breast cancer MCF-7 cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060801
Anti-estrogen ICI 182.780 and anti-androgen flutamide induce tyrosine phosphorylation of cortactin in the ectoplasmic specialization between the Sertoli cell and spermatids in the mouse testis. Biochemical and biophysical research communications 20060721
Gene expression preferentially regulated by tamoxifen in breast cancer cells and correlations with clinical outcome. Cancer research 20060715
Progesterone receptor antagonist is effective in relieving neuropathic pain. European journal of pharmacology 20060710
Neuroprotective effects of 17beta-estradiol and nonfeminizing estrogens against H2O2 toxicity in human neuroblastoma SK-N-SH cells. Molecular pharmacology 20060701
Estrogens cross-talk to alpha1b-adrenergic receptors. Molecular pharmacology 20060701
Prenatal estrogen and progesterone deprivation impairs alveolar formation and fluid clearance in newborn piglets. Pediatric research 20060701
Hypoxic activation of unoccupied estrogen-receptor-alpha is mediated by hypoxia-inducible factor-1 alpha. The Journal of steroid biochemistry and molecular biology 20060701
Administration of xenobiotics with anti-estrogenic effects results in mRNA induction of adult male-specific cytochrome P450 isozymes in the livers of adult female rats. Journal of pharmacological sciences 20060701
Expression of estrogen receptors-alpha and -beta in bladder cancer cell lines and human bladder tumor tissue. Cancer 20060615
Comparative assessment of lipid effects of endocrine therapy for breast cancer: implications for cardiovascular disease prevention in postmenopausal women. Breast (Edinburgh, Scotland) 20060601
Dynamic changes in dopaminergic neurotransmission induced by a low concentration of bisphenol-A in neurones and astrocytes. Journal of neuroendocrinology 20060601
The susceptibility of granulosa cells to apoptosis is influenced by oestradiol and the cell cycle. The Journal of endocrinology 20060601
Genistein modulates the effects of parathyroid hormone in human osteoblastic SaOS-2 cells. The British journal of nutrition 20060601
New therapies in the treatment of breast cancer. Seminars in oncology 20060601
Fulvestrant (ICI 182,780) down-regulates androgen receptor expression and diminishes androgenic responses in LNCaP human prostate cancer cells. Molecular cancer therapeutics 20060601
Estrogenic compounds inhibit gap junctional intercellular communication in mouse Leydig TM3 cells. Toxicology and applied pharmacology 20060501
Regulation of BCRP/ABCG2 expression by progesterone and 17beta-estradiol in human placental BeWo cells. American journal of physiology. Endocrinology and metabolism 20060501
Dioxin induces an estrogen-like, estrogen receptor-dependent gene expression response in the murine uterus. Molecular pharmacology 20060501
Synthetic 19-nortestosterone derivatives as estrogen receptor alpha subtype-selective ligands induce similar receptor conformational changes and steroid receptor coactivator recruitment than natural estrogens. The Journal of steroid biochemistry and molecular biology 20060501
Uterotrophic effects of relaxin related to age and estrogen receptor activation in neonatal pigs. Reproduction (Cambridge, England) 20060501
[Regulatory effect of 17beta-estradiol on expression of orphan nuclear receptor ERRalpha in endometrial carcinoma cell lines]. Ai zheng = Aizheng = Chinese journal of cancer 20060501
[Estrogenic activity and its mechanism of ethanol extract from black soybean]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060501
Tamoxifen and estradiol interact with the flavin mononucleotide site of complex I leading to mitochondrial failure. The Journal of biological chemistry 20060414
Effects of oestrogens and anti-oestrogens on normal breast tissue from women bearing BRCA1 and BRCA2 mutations. British journal of cancer 20060410
Fulvestrant (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-alpha. The Journal of biological chemistry 20060407
Rapid action of pesticides on cytosolic calcium concentrations in cultures of human umbilical vein endothelial cells. Reproductive toxicology (Elmsford, N.Y.) 20060401
Overexpression of estrogen receptor alpha increases hepatic cholesterogenesis, leading to biliary hypersecretion in mice. Journal of lipid research 20060401
Participation of estrogen receptors in the enhancement of osteoblast differentiation by TAK-778. Molecular and cellular biochemistry 20060401
Virtual and biomolecular screening converge on a selective agonist for GPR30. Nature chemical biology 20060401
Oestrogen receptor subtype-specific repression of calpain expression and calpain enzymatic activity in neuronal cells--implications for neuroprotection against Ca-mediated excitotoxicity. Journal of neurochemistry 20060401
Changes in oestrogen receptor-alpha and -beta during progression to acquired resistance to tamoxifen and fulvestrant (Faslodex, ICI 182,780) in MCF7 human breast cancer cells. The Journal of steroid biochemistry and molecular biology 20060401
Estrogens modulate the gene expression of Wnt-7a in cultured endometrial adenocarcinoma cells. Molecular nutrition & food research 20060401
Estradiol and its membrane-impermeable conjugate estradiol-BSA inhibit tamoxifen-stimulated prolactin secretion in incubated rat pituitaries. Reproduction (Cambridge, England) 20060401
Development and therapeutic options for the treatment of raloxifene-stimulated breast cancer in athymic mice. Clinical cancer research : an official journal of the American Association for Cancer Research 20060401
ICI 182,780-regulated gene expression in DU145 prostate cancer cells is mediated by estrogen receptor-beta/NFkappaB crosstalk. Neoplasia (New York, N.Y.) 20060401
Prenylflavonoids as nonsteroidal phytoestrogens and related structure-activity relationships. ChemMedChem 20060401
Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation. Molecular endocrinology (Baltimore, Md.) 20060301
Estrogen receptor alpha mediates acute potassium channel stimulation in human coronary artery smooth muscle cells. The Journal of pharmacology and experimental therapeutics 20060301
Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue. Molecular pharmacology 20060301
Inhibition of MCF-7 breast cancer cell proliferation by MCF-10A breast epithelial cells in coculture. Cell biology international 20060301
Estrogen induces death of tamoxifen-resistant MCF-7 cells: contrasting effect of the estrogen receptor downregulator fulvestrant. The Journal of steroid biochemistry and molecular biology 20060301
Ethanol stimulates the secretion of matrix metalloproteinases 2 and 9 in MCF-7 human breast cancer cells. Oncology reports 20060301
Fulvestrant ('Faslodex'): current and future role in breast cancer management. Critical reviews in oncology/hematology 20060301
Fulvestrant in women with advanced breast cancer after progression on prior aromatase inhibitor therapy: North Central Cancer Treatment Group Trial N0032. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060301
Endocrine response after prior treatment with fulvestrant in postmenopausal women with advanced breast cancer: experience from a single centre. Endocrine-related cancer 20060301
3-Methylcholanthrene and other aryl hydrocarbon receptor agonists directly activate estrogen receptor alpha. Cancer research 20060215
Fulvestrant, a new treatment option for advanced breast cancer: tolerability versus existing agents. Annals of oncology : official journal of the European Society for Medical Oncology 20060201
Durable response of metastatic endometrial carcinoma to treatment with fulvestrant (Faslodex) after prior progestin and anastrozole therapy. Gynecologic oncology 20060201
Effect of methoxychlor and estradiol on cytochrome p450 enzymes in the mouse ovarian surface epithelium. Toxicological sciences : an official journal of the Society of Toxicology 20060201
Mechanism of the salutary effects of flutamide on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of estrogen receptor-{beta}-dependent HO-1. Journal of leukocyte biology 20060201
Estrogenic properties of isoflavones derived from Millettia griffoniana. Phytomedicine : international journal of phytotherapy and phytopharmacology 20060201
Locally produced estrogen promotes fetal rat metatarsal bone growth; an effect mediated through increased chondrocyte proliferation and decreased apoptosis. The Journal of endocrinology 20060201
DNA damage caused by bisphenol A and estradiol through estrogenic activity. Biological & pharmaceutical bulletin 20060201
17beta-estradiol potentiates the cardiac cystic fibrosis transmembrane conductance regulator chloride current in guinea-pig ventricular myocytes. The journal of physiological sciences : JPS 20060201
Relaxin-induced reduction of infarct size in male rats receiving MCAO is dependent on nitric oxide synthesis and not estrogenic mechanisms. Neuroscience letters 20060130
Effects of endocrine disrupters on the expression of growth hormone and prolactin mRNA in the rainbow trout pituitary. General and comparative endocrinology 20060115
Characterization of estrogen receptor betab in sea bream (Sparus auratus): phylogeny, ligand-binding, and comparative analysis of expression. General and comparative endocrinology 20060115
Flutamide restores cardiac function after trauma-hemorrhage via an estrogen-dependent pathway through upregulation of PGC-1. American journal of physiology. Heart and circulatory physiology 20060101
Mechanism of cardioprotection following trauma-hemorrhagic shock by a selective estrogen receptor-beta agonist: up-regulation of cardiac heat shock factor-1 and heat shock proteins. Journal of molecular and cellular cardiology 20060101
Antiestrogens modulate MT1 melatonin receptor expression in breast and ovarian cancer cell lines. Oncology reports 20060101
Additive growth inhibitory effects of ibandronate and antiestrogens in estrogen receptor-positive breast cancer cell lines. Breast cancer research : BCR 20060101
The estrogen metabolite 17beta-dihydroequilenin counteracts interleukin-1alpha induced expression of inflammatory mediators in human endothelial cells in vitro via NF-kappaB pathway. Thrombosis and haemostasis 20060101
Prognostic value of monitoring tumour markers CA 15-3 and CEA during fulvestrant treatment. BMC cancer 20060101
DHEA-induced antiproliferative effect in MCF-7 cells is androgen- and estrogen receptor-independent. Cancer journal (Sudbury, Mass.) 20060101
[Fulvestrant: a new agent in endocrine treatment for breast cancer]. Lijecnicki vjesnik 20060101
Rapid Ca(2+) signaling induced by Bisphenol A in cultured rat hippocampal neurons. Neuro endocrinology letters 20060101
AIB1 gene amplification and the instability of polyQ encoding sequence in breast cancer cell lines. BMC cancer 20060101
Inhibition of proliferation of endometrial stromal cells by trichostatin A, RU486, CDB-2914, N-acetylcysteine, and ICI 182780. Gynecologic and obstetric investigation 20060101
Estrogen and raloxifene inhibit the monocytic chemoattractant protein-1-induced migration of human monocytic cells via nongenomic estrogen receptor alpha. Menopause (New York, N.Y.) 20060101
Is fulvestrant ('Faslodex') just another selective estrogen receptor modulator? International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Metastatic breast cancer: sequencing hormonal therapy and positioning of fulvestrant. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101
Estrogens, selective estrogen receptor modulators, and a selective estrogen receptor down-regulator inhibit endothelial production of tissue factor pathway inhibitor 1. BMC cardiovascular disorders 20060101
Estrogen receptor-alpha (ER-alpha) and defects in uterine receptivity in women. Reproductive biology and endocrinology : RB&E 20060101
ICI 182,780 has agonistic effects and synergizes with estradiol-17 beta in fish liver, but not in testis. Reproductive biology and endocrinology : RB&E 20060101
ERE-independent ERalpha target genes differentially expressed in human breast tumors. Molecular and cellular endocrinology 20051221
Intrinsic mechanism of estradiol-induced apoptosis in breast cancer cells resistant to estrogen deprivation. Journal of the National Cancer Institute 20051207
Lignans, bacteriocides and organochlorine compounds activate the human pregnane X receptor (PXR). Toxicology and applied pharmacology 20051201
Progestin activation of nongenomic pathways via cross talk of progesterone receptor with estrogen receptor beta induces proliferation of endometrial stromal cells. Molecular endocrinology (Baltimore, Md.) 20051201
CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-alpha. Molecular endocrinology (Baltimore, Md.) 20051201
Dehydroepiandrosterone restoration of growth hormone gene expression in aging female rats, in vivo and in vitro: evidence for actions via estrogen receptors. Endocrinology 20051201
Adjuvant endocrine therapies for postmenopausal women with early breast cancer: standards and not. Breast (Edinburgh, Scotland) 20051201
Role of mitochondria in tamoxifen-induced rapid death of MCF-7 breast cancer cells. Apoptosis : an international journal on programmed cell death 20051201
Complex agonist-like properties of ICI 182,780 (Faslodex) in human breast cancer cells that predominantly express progesterone receptor-B: implications for treatment resistance. International journal of oncology 20051201
Estrogen and testosterone use different cellular pathways to inhibit osteoclastogenesis and bone resorption. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20051201
Multitargeted therapy in estrogen receptor-positive, human epidermal growth factor receptor-2-positive breast cancer. American journal of clinical oncology 20051201
MCT-1 oncogene contributes to increased in vivo tumorigenicity of MCF7 cells by promotion of angiogenesis and inhibition of apoptosis. Cancer research 20051201
The anti-oestrogen ICI 182,780, but not tamoxifen, inhibits the growth of MCF-7 breast cancer cells refractory to long-term oestrogen deprivation through down-regulation of oestrogen receptor and IGF signalling. Endocrine-related cancer 20051201
Role of estrogen receptor (ER) alpha in insulin-like growth factor (IGF)-I-induced responses in MCF-7 breast cancer cells. Journal of molecular endocrinology 20051201
Tissue-specific modulation of cyclooxygenase-2 (Cox-2) expression in the uterus and the v. cava by estrogens and phytoestrogens. Molecular and cellular endocrinology 20051124
Comparative effect of seeds of Rhynchosia volubilis and soybean on MG-63 human osteoblastic cell proliferation and estrogenicity. Life sciences 20051119
Activation of estrogen receptor-alpha protects the in vivo rabbit heart from ischemia-reperfusion injury. American journal of physiology. Heart and circulatory physiology 20051101
Estrogen receptor alpha increases basal and cigarette smoke extract-induced expression of CYP1A1 and CYP1B1, but not GSTP1, in normal human bronchial epithelial cells. Molecular carcinogenesis 20051101
No estrogen-like effects of an isopropanolic extract of Rhizoma Cimicifugae racemosae on uterus and vena cava of rats after 17 day treatment. The Journal of steroid biochemistry and molecular biology 20051101
Fulvestrant ('Faslodex') in pre-treated patients with advanced breast cancer: a single-centre experience. European journal of cancer (Oxford, England : 1990) 20051101
Isopropanolic extract of black cohosh stimulates osteoprotegerin production by human osteoblasts. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20051101
Estrogenic induction of spermatogenesis in the hypogonadal (hpg) mouse: role of androgens. Reproduction (Cambridge, England) 20051101
Investigation of central versus peripheral effects of estradiol in ovariectomized mice. The Journal of endocrinology 20051101
Estrogenic effects of two derivatives of icariin on human breast cancer MCF-7 cells. Phytomedicine : international journal of phytotherapy and phytopharmacology 20051101
17beta-estradiol protects SH-SY5Y Cells against HIV-1 gp120-induced cell death: evidence for a role of estrogen receptors. Neurotoxicology 20051001
The effects of blocking the actions of estrogen and progesterone on the rates of proliferation and apoptosis of cervical epithelial and stromal cells during the second half of pregnancy in rats. Biology of reproduction 20051001
Estrogen increases mitochondrial efficiency and reduces oxidative stress in cerebral blood vessels. Molecular pharmacology 20051001
Growth-plate chondrocytes respond to 17beta-estradiol with sex-specific increases in IP3 and intracellular calcium ion signalling via a capacitative entry mechanism. Steroids 20051001
Differential effects of estrogen on DNA synthesis in human periodontal ligament and breast cancer cells. Journal of periodontal research 20051001
Analysis of estrogen agonism and antagonism of tamoxifen, raloxifene, and ICI182780 in endometrial cancer cells: a putative role for the epidermal growth factor receptor ligand amphiregulin. Journal of the Society for Gynecologic Investigation 20051001
The phytoestrogen biochaninA weakens acute cardiac allograft rejection without affecting the reproductive system. Transplant immunology 20051001
Differential effect of estrogen receptor alpha and beta agonists on the receptor for advanced glycation end product expression in human microvascular endothelial cells. Biochimica et biophysica acta 20050930
Glycogen synthase kinase-3 interacts with and phosphorylates estrogen receptor alpha and is involved in the regulation of receptor activity. The Journal of biological chemistry 20050923
Estrogen receptor-alpha regulates SOCS-3 expression in human breast cancer cells. Biochemical and biophysical research communications 20050916
Diffusion-time distribution analysis reveals characteristic ligand-dependent interaction patterns of nuclear receptors in living cells. Biochemistry 20050906
The red wine polyphenol, resveratrol, exerts acute direct actions on guinea-pig ventricular myocytes. European journal of pharmacology 20050905
Non-genomic action of estradiol and progesterone on cytosolic calcium concentrations in primary cultures of human granulosa-lutein cells. Human reproduction (Oxford, England) 20050901
The estrogen receptor-alpha agonist 16alpha-LE2 inhibits cardiac hypertrophy and improves hemodynamic function in estrogen-deficient spontaneously hypertensive rats. Cardiovascular research 20050901
Estrogen receptor ligands. Part 13: Dihydrobenzoxathiin SERAMs with an optimized antagonist side chain. Bioorganic & medicinal chemistry letters 20050901
Dehydroepiandrosterone sulfate induces acute vasodilation of porcine coronary arteries in vitro and in vivo. Journal of cardiovascular pharmacology 20050901
Alternative splicing of Slo channel gene programmed by estrogen, progesterone and pregnancy. FEBS letters 20050829
Effect of follicle-stimulating hormone and estrogen on the expression of betaglycan messenger ribonucleic acid levels in cultured rat granulosa cells. Endocrinology 20050801
Selective oestrogen receptor modulators, aromatase inhibitors and the female breast. Current opinion in obstetrics & gynecology 20050801
Estrogen-induced growth inhibition of human seminoma cells expressing estrogen receptor beta and aromatase. Journal of molecular endocrinology 20050801
A selective estrogen receptor modulator, tamoxifen, and membrane fluidity of erythrocytes in normotensive and hypertensive postmenopausal women: an electron paramagnetic resonance investigation. American journal of hypertension 20050801
A short-incubation reporter-gene assay for high-throughput screening of estrogen receptor-alpha antagonists. Assay and drug development technologies 20050801
Regulation of glutamate transporter GLAST and GLT-1 expression in astrocytes by estrogen. Brain research. Molecular brain research 20050729
Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma: a prospectively planned combined survival analysis of two multicenter trials. Cancer 20050715
Differential effects of estrogen receptor antagonists on pituitary lactotroph proliferation and prolactin release. Molecular and cellular endocrinology 20050715
Opposite effects of estrogen receptors alpha and beta on MCF-7 sensitivity to the cytotoxic action of TNF and p53 activity. Oncogene 20050714
A nongenomic action of 17beta-estradiol as the mechanism underlying the acute suppression of secretion of luteinizing hormone. Biology of reproduction 20050701
Estrogen modulates endothelial and neuronal nitric oxide synthase expression via an estrogen receptor beta-dependent mechanism in hypothalamic slice cultures. Endocrinology 20050701
Coplanar PCB congeners increase uterine weight and frontal cortical dopamine in the developing rat: implications for developmental neurotoxicity. Toxicological sciences : an official journal of the Society of Toxicology 20050701
Sensitivity to further endocrine therapy is retained following progression on first-line fulvestrant. Breast cancer research and treatment 20050701
Effects of 17beta-estradiol on chemically induced long-term depression. Neuropharmacology 20050701
A paradoxical inhibitory effect of oestradiol-17beta on GnRH self-priming in pituitaries from tamoxifen-treated rats. The Journal of endocrinology 20050701
Elevated ERK1/ERK2/estrogen receptor cross-talk enhances estrogen-mediated signaling during long-term estrogen deprivation. Endocrine-related cancer 20050701
Estrogen therapy for experimental intracerebral hemorrhage in rats. Journal of neurosurgery 20050701
Significance of HDAC6 regulation via estrogen signaling for cell motility and prognosis in estrogen receptor-positive breast cancer. Oncogene 20050630
Estrogen-induced loss of progesterone receptor expression in normal and malignant ovarian surface epithelial cells. Oncogene 20050623
[Regulation of orphan receptor ERR alpha by estrogen and progesterone in endometrial carcinoma cell line]. Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20050618
Gene expression changes in rat prostate after activation or blocking of the androgen and estrogen receptor. Molecular and cellular endocrinology 20050615
Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model. Cancer research 20050615
Molecular and functional signature of heart hypertrophy during pregnancy. Circulation research 20050610
Distinctive actions of membrane-targeted versus nuclear localized estrogen receptors in breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20050601
Dose-dependent effects of 4-hydroxytamoxifen, the active metabolite of tamoxifen, on estrogen receptor-alpha expression in the rat uterus. Anti-cancer drugs 20050601
Aquaporin-1 and -9 are differentially regulated by oestrogen in the efferent ductule epithelium and initial segment of the epididymis. Biology of the cell 20050601
The estrogenic activity of synthetic progestins used in oral contraceptives enhances fatty acid synthase-dependent breast cancer cell proliferation and survival. International journal of oncology 20050601
CSN5/Jab1 is involved in ligand-dependent degradation of estrogen receptor {alpha} by the proteasome. Molecular and cellular biology 20050601
A comparison of fulvestrant and the third-generation aromatase inhibitors in the second-line treatment of postmenopausal women with advanced breast cancer. Cancer treatment reviews 20050601
Oestrogen does not affect the restoration of spermatogenesis in the gonadotrophin-releasing hormone-immunised adult rat. The Journal of endocrinology 20050601
Regulation of vitamin D receptor expression via estrogen-induced activation of the ERK 1/2 signaling pathway in colon and breast cancer cells. The Journal of endocrinology 20050601
Selected highlights from the 27th San Antonio Breast Cancer Symposium. San Antonio, TX, USA, 8-11 December 2004. Expert opinion on pharmacotherapy 20050601
Fulvestrant in the treatment of postmenopausal women with advanced breast cancer. Expert review of anticancer therapy 20050601
Gender differences in renal tubular taurocholate transport. Naunyn-Schmiedeberg's archives of pharmacology 20050601
Estrogen induces vascular wall dilation: mediation through kinase signaling to nitric oxide and estrogen receptors alpha and beta. The Journal of biological chemistry 20050520
Expression and estrogen-dependent regulation of the zebrafish brain aromatase gene. The Journal of comparative neurology 20050516
Uterine blood flow responses to ICI 182 780 in ovariectomized oestradiol-17beta-treated, intact follicular and pregnant sheep. The Journal of physiology 20050515
Suppression of ps20 expression in the rat uterus by tamoxifen and estrogens. Endocrinology 20050501
Promoting insulin secretion in pancreatic islets by means of bisphenol A and nonylphenol via intracellular estrogen receptors. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050501
Estrogen specifically stimulates expression and production of osteoprotegerin from rheumatoid synovial fibroblasts. International journal of molecular medicine 20050501
Effect of oestradiol on mouse uterine epithelial cell tumour necrosis factor-alpha release is mediated through uterine stromal cells. Immunology 20050501
Suppression of experimental autoimmune encephalomyelitis using estrogen receptor-selective ligands. The Journal of endocrinology 20050501
Estrogen protects primary osteocytes against glucocorticoid-induced apoptosis. Apoptosis : an international journal on programmed cell death 20050501
Anti-inflammatory effect of selective estrogen receptor modulators (SERMs) in microglial cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050501
Model systems: mechanisms involved in the loss of sensitivity to letrozole. The Journal of steroid biochemistry and molecular biology 20050501
Aromatase inhibitors: combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance. The Journal of steroid biochemistry and molecular biology 20050501
[Fulvestrant]. Ugeskrift for laeger 20050418
Hormonal regulation of the Grb14 signal modulator and its role in cell cycle progression of MCF-7 human breast cancer cells. Journal of cellular physiology 20050401
Estrogen receptor alpha pathway is involved in the regulation of Calbindin-D9k in the uterus of immature rats. Toxicological sciences : an official journal of the Society of Toxicology 20050401
Transcriptional activation of the oxytocin promoter by oestrogens uses a novel non-classical mechanism of oestrogen receptor action. Journal of neuroendocrinology 20050401
Role of fulvestrant in sequential hormonal therapy for advanced, hormone receptor-positive breast cancer in postmenopausal women. Clinical breast cancer 20050401
Current and future perspectives on fulvestrant. Clinical breast cancer 20050401
Clinical value of fulvestrant in breast cancer. Clinical breast cancer 20050401
The history and mechanism of action of fulvestrant. Clinical breast cancer 20050401
Effectiveness and tolerability of fulvestrant in postmenopausal women with hormone receptor-positive breast cancer. Clinical breast cancer 20050401
Molecular basis of estrogen-induced cyclooxygenase type 1 upregulation in endothelial cells. Circulation research 20050318
Signal transduction. A new mediator for an old hormone? Science (New York, N.Y.) 20050311
[New strategies against breast carcinoma. To outwit the resistance tendency of tumor cells]. MMW Fortschritte der Medizin 20050310
Resveratrol and estradiol rapidly activate MAPK signaling through estrogen receptors alpha and beta in endothelial cells. The Journal of biological chemistry 20050304
Raloxifene relaxes rat pulmonary arteries and veins: roles of gender, endothelium, and antagonism of Ca2+ influx. The Journal of pharmacology and experimental therapeutics 20050301
The putative tumor suppressor deleted in malignant brain tumors 1 is an estrogen-regulated gene in rodent and primate endometrial epithelium. Endocrinology 20050301
Hair cycle control by estrogens: catagen induction via estrogen receptor (ER)-alpha is checked by ER beta signaling. Endocrinology 20050301
Modulation of osteoclastogenesis in porcine bone marrow cultures by quercetin and rutin. Cell and tissue research 20050301
Improvement of portal hypertension and hepatic blood flow in cirrhotic rats by oestrogen. European journal of clinical investigation 20050301
Innovations in antineoplastic therapy. The Nursing clinics of North America 20050301
Differential effects of estrogens and progestins on the anticoagulant tissue factor pathway inhibitor in the rat. The Journal of steroid biochemistry and molecular biology 20050301
Combined targeting of the estrogen receptor and the epidermal growth factor receptor in non-small cell lung cancer shows enhanced antiproliferative effects. Cancer research 20050215
Regulation of endogenous gene expression in human non-small cell lung cancer cells by estrogen receptor ligands. Cancer research 20050215
ICI182,780 induces p21Waf1 gene transcription through releasing histone deacetylase 1 and estrogen receptor alpha from Sp1 sites to induce cell cycle arrest in MCF-7 breast cancer cell line. The Journal of biological chemistry 20050204
Co-culture of primary human mammary fibroblasts and MCF-7 cells as an in vitro breast cancer model. Toxicological sciences : an official journal of the Society of Toxicology 20050201
Methoxychlor induces proliferation of the mouse ovarian surface epithelium. Toxicological sciences : an official journal of the Society of Toxicology 20050201
Genistein stimulates the osteoblastic differentiation via NO/cGMP in bone marrow culture. Journal of cellular biochemistry 20050201
Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays. Toxicological sciences : an official journal of the Society of Toxicology 20050201
Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 20050201
Deregulation of cell proliferation by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells reflects both genotoxic and nongenotoxic events. Toxicological sciences : an official journal of the Society of Toxicology 20050201
The estrogen antagonist ICI-182-780 does not inhibit the transformation phenotypes induced by 17-beta-estradiol and 4-OH estradiol in human breast epithelial cells. International journal of oncology 20050201
Fulvestrant--ready to start its journey in the breast cancer adjuvant endocrine world? European journal of cancer (Oxford, England : 1990) 20050201
Endocrine treatment options for advanced breast cancer--the role of fulvestrant. European journal of cancer (Oxford, England : 1990) 20050201
Basis of melengestrol acetate action as a progestin. Domestic animal endocrinology 20050201
Estrogen receptor independent rapid non-genomic effects of environmental estrogens on [Ca2+]i in human breast cancer cells. Molecular and cellular endocrinology 20050131
Estradiol and endocrine disrupting compounds adversely affect development of sea urchin embryos at environmentally relevant concentrations. Aquatic toxicology (Amsterdam, Netherlands) 20050126
Therapeutic observations in MCF-7 aromatase xenografts. Clinical cancer research : an official journal of the American Association for Cancer Research 20050115
17beta-Estradiol rapidly stimulates c-fos expression via the MAPK pathway in T84 cells. Molecular and cellular endocrinology 20050114
Cytochromes 1A1/1B1- and catechol-O-methyltransferase-derived metabolites mediate estradiol-induced antimitogenesis in human cardiac fibroblast. The Journal of clinical endocrinology and metabolism 20050101
Novel progestogenic activity of environmental endocrine disruptors in the upregulation of calbindin-D9k in an immature mouse model. Toxicological sciences : an official journal of the Society of Toxicology 20050101
Bis(ethyl)norspermine potentiates the apoptotic activity of the pure antiestrogen ICI 182780 in breast cancer cells. Oncology reports 20050101
The nuclear factor kappa B inhibitor parthenolide restores ICI 182,780 (Faslodex; fulvestrant)-induced apoptosis in antiestrogen-resistant breast cancer cells. Molecular cancer therapeutics 20050101
AND-34 activates phosphatidylinositol 3-kinase and induces anti-estrogen resistance in a SH2 and GDP exchange factor-like domain-dependent manner. Molecular cancer research : MCR 20050101
TAS-108, a novel oral steroidal antiestrogenic agent, is a pure antagonist on estrogen receptor alpha and a partial agonist on estrogen receptor beta with low uterotrophic effect. Clinical cancer research : an official journal of the American Association for Cancer Research 20050101
Effects of ICI 182780 on estrogen receptor expression, fluid absorption and sperm motility in the epididymis of the bonnet monkey. Reproductive biology and endocrinology : RB&E 20050101
Preclinical and clinical experience with fulvestrant (Faslodex) in postmenopausal women with hormone receptor-positive advanced breast cancer. Cancer investigation 20050101
Estrogen and growth factor receptor interactions in human breast and non-small cell lung cancer cells. Steroids 20050101
Gonadal steroids differentially modulate neurotoxicity of HIV and cocaine: testosterone and ICI 182,780 sensitive mechanism. BMC neuroscience 20050101
Receptor isoform and ligand-specific modulation of dihydrotestosterone-induced prostate specific antigen gene expression and prostate tumor cell growth by estrogens. Journal of andrology 20050101
Endocrinology and hormone therapy in breast cancer: selective oestrogen receptor modulators and downregulators for breast cancer - have they lost their way? Breast cancer research : BCR 20050101
Estren promotes androgen phenotypes in primary lymphoid organs and submandibular glands. BMC immunology 20050101
Oestrogenic activity of p-hydroxybenzoic acid (common metabolite of paraben esters) and methylparaben in human breast cancer cell lines. Journal of applied toxicology : JAT 20050101
Evidence that 17alpha-estradiol is biologically active in the uterine tissue: antiuterotonic and antiuterotrophic action. Reproductive biology and endocrinology : RB&E 20050101
Expression and regulation of retinoid-inducible gene 1 (RIG1) in breast cancer. Anticancer research 20050101
17beta-estradiol inhibits outward potassium currents recorded in rat parabrachial nucleus cells in vitro. Neuroscience 20050101
Estrogen synthesis in the central nucleus of the amygdala following middle cerebral artery occlusion: role in modulating neurotransmission. Neuroscience 20050101
Differential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells. Breast cancer research : BCR 20050101
Clinical development of fulvestrant ('Faslodex'). Cancer treatment reviews 20050101
The future of fulvestrant ('Faslodex'). Cancer treatment reviews 20050101
Fulvestrant ('Faslodex'): clinical experience from the Compassionate Use Programme. Cancer treatment reviews 20050101
Case studies of fulvestrant ('Faslodex') in postmenopausal women with advanced breast cancer. Cancer treatment reviews 20050101
Fulvestrant ('Faslodex'): extending the reach of endocrine therapy? Breast cancer research and treatment 20050101
Endocrine therapy--current benefits and limitations. Breast cancer research and treatment 20050101
Biological characteristics of the pure antiestrogen fulvestrant: overcoming endocrine resistance. Breast cancer research and treatment 20050101
Life following aromatase inhibitors--where now for endocrine sequencing? Breast cancer research and treatment 20050101
17Beta-estradiol suppresses TLR3-induced cytokine and chemokine production in endometrial epithelial cells. Reproductive biology and endocrinology : RB&E 20050101
Treatment of Postmenopausal Breast Cancer with Selective Estrogen Receptor Modulators (SERMs). Breast disease 20050101
Insulin-like growth factor-I receptor and estrogen receptor crosstalk mediates hormone-induced neurite outgrowth in PC12 cells. Brain research 20041224
Effect of anti-estrogens on the androgen receptor activity and cell proliferation in prostate cancer cells. Urological research 20041201
The cooked food derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b] pyridine is a potent oestrogen: a mechanistic basis for its tissue-specific carcinogenicity. Carcinogenesis 20041201
Effect of genistein as a selective estrogen receptor beta agonist on the expression of Calbindin-D9k in the uterus of immature rats. Toxicological sciences : an official journal of the Society of Toxicology 20041201
Induction of the paraoxonase-1 gene expression by resveratrol. Arteriosclerosis, thrombosis, and vascular biology 20041201
Recruitment of uterine NK cells: induction of CXC chemokine ligands 10 and 11 in human endometrium by estradiol and progesterone. Journal of immunology (Baltimore, Md. : 1950) 20041201
Fulvestrant - a new treatment for postmenopausal women with hormone-sensitive advanced breast cancer. Expert opinion on pharmacotherapy 20041201
Tamoxifen exerts agonistic effects on clusterin and complement C3 gene expression in RUCA-I primary xenografts and metastases but not normal uterus. Endocrine-related cancer 20041201
Advances in endocrine therapy for breast cancer: considering efficacy, safety, and quality of life. Clinical journal of oncology nursing 20041201
Selective estrogen receptor modulators prevent neointima formation after vascular injury. Molecular and cellular endocrinology 20041130
Proliferation-stimulating effects of icaritin and desmethylicaritin in MCF-7 cells. European journal of pharmacology 20041119
P-cadherin is up-regulated by the antiestrogen ICI 182,780 and promotes invasion of human breast cancer cells. Cancer research 20041115
Estrogen modulates microglial inflammatory mediator production via interactions with estrogen receptor beta. Endocrinology 20041101
Endocrine approaches for the treatment of early and advanced breast cancer in postmenopausal women. The international journal of biochemistry & cell biology 20041101
Steroid-free medium discloses oestrogenic effects of the bisphosphonate clodronate on breast cancer cells. British journal of cancer 20041101
Tissue-specific effect of estradiol on endothelial cell-dependent lymphocyte recruitment. Microvascular research 20041101
Xenoestrogen-induced ERK-1 and ERK-2 activation via multiple membrane-initiated signaling pathways. Environmental health perspectives 20041101
Response to fulvestrant in heavily pretreated postmenopausal women: a single-center experience. Breast cancer research and treatment 20041101
Is fulvestrant more effective than tamoxifen for treating ER-positive breast cancer in postmenopausal women? Nature clinical practice. Oncology 20041101
Intracellular signaling involved in estrogen regulation of serotonin reuptake. Molecular and cellular endocrinology 20041029
Estrogen induces nitric oxide production via activation of constitutive nitric oxide synthases in human neuroblastoma cells. Endocrinology 20041001
Oestradiol rapidly inhibits Ca2+ signals in ciliary neurons through classical oestrogen receptors in cytoplasm. Pflugers Archiv : European journal of physiology 20041001
Relaxant effects of estradiol through non-genomic pathways in male and female pig bladder smooth muscle. Pharmacology 20041001
17beta-estradiol reduces cardiomyocyte apoptosis in vivo and in vitro via activation of phospho-inositide-3 kinase/Akt signaling. Circulation research 20041001
Understanding the biologic mechanisms responsible for breast-cancer progression during tamoxifen or fulvestrant treatment. American journal of surgery 20041001
Leptin interferes with the effects of the antiestrogen ICI 182,780 in MCF-7 breast cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20041001
Synthesis and biological evaluation of stilbene-based pure estrogen antagonists. Bioorganic & medicinal chemistry letters 20040920
Development and characterization of a cell line that stably expresses an estrogen-responsive luciferase reporter for the detection of estrogen receptor agonist and antagonists. Toxicological sciences : an official journal of the Society of Toxicology 20040901
Estrogen and mu-opioid receptor antagonists counteract the 17 beta-estradiol-induced licking increase and interferon-gamma reduction occurring during the formalin test in male rats. Pain 20040901
Dehydroepiandrosterone increases endothelial cell proliferation in vitro and improves endothelial function in vivo by mechanisms independent of androgen and estrogen receptors. The Journal of clinical endocrinology and metabolism 20040901
Estrogen induced changes in Akt-dependent activation of endothelial nitric oxide synthase and vasodilation. Steroids 20040901
Endogenous estrogen receptor beta is transcriptionally active in primary ovarian cells from estrogen receptor knockout mice. Steroids 20040901
Fulvestrant: a new type of estrogen receptor antagonist for the treatment of advanced breast cancer. Drugs of today (Barcelona, Spain : 1998) 20040901
Non-classical regulation of estrogen receptor-alpha by ICI182,780. The Journal of steroid biochemistry and molecular biology 20040901
Genistein inhibits expressions of NADPH oxidase p22phox and angiotensin II type 1 receptor in aortic endothelial cells from stroke-prone spontaneously hypertensive rats. Hypertension research : official journal of the Japanese Society of Hypertension 20040901
Estrogen and phytoestrogen regulate the mRNA expression of adrenomedullin and adrenomedullin receptor components in the rat uterus. Molecular and cellular endocrinology 20040831
Estrogen induces expression of secretory leukocyte protease inhibitor in rat uterus. Biology of reproduction 20040801
Effects of the pesticides prochloraz and methiocarb on human estrogen receptor alpha and beta mRNA levels analyzed by on-line RT-PCR. Toxicology in vitro : an international journal published in association with BIBRA 20040801
A low dose of daidzein acts as an ERbeta-selective agonist in trabecular osteoblasts of young female piglets. Journal of cellular physiology 20040801
Daidzein and 17 beta-estradiol enhance nitric oxide synthase activity associated with an increase in calmodulin and a decrease in caveolin-1. Journal of cardiovascular pharmacology 20040801
Impact on estrogen receptor binding and target tissue uptake of [18F]fluorine substitution at the 16alpha-position of fulvestrant (faslodex; ICI 182,780). Nuclear medicine and biology 20040801
Extracellular calcium downregulates estrogen receptor alpha and increases its transcriptional activity through calcium-sensing receptor in breast cancer cells. Bone 20040801
Mifepristone induces growth arrest, caspase activation, and apoptosis of estrogen receptor-expressing, antiestrogen-resistant breast cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20040801
Soybean isoflavones eliminate nifedipine-induced flushing of tail skin in ovariectomized mice. Journal of pharmacological sciences 20040801
Direct action of estradiol on gonadotropin-releasing hormone-1 neuronal activity via a transcription-dependent mechanism. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040714
Antiestrogens induce growth inhibition by sequential activation of p38 mitogen-activated protein kinase and transforming growth factor-beta pathways in human breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20040701
Estrogen and neuroprotection: higher constitutive expression of glutaredoxin in female mice offers protection against MPTP-mediated neurodegeneration. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701
Prolonged extracellular signal-regulated kinase 1/2 activation during fibroblast growth factor 1- or heregulin beta1-induced antiestrogen-resistant growth of breast cancer cells is resistant to mitogen-activated protein/extracellular regulated kinase kinase inhibitors. Cancer research 20040701
Estrogen receptor alpha, but not beta, plays a major role in 17beta-estradiol-induced murine cholesterol gallstones. Gastroenterology 20040701
Mitochondrial localization of ERalpha and ERbeta in human MCF7 cells. American journal of physiology. Endocrinology and metabolism 20040601
Estradiol stimulation of pulsatile gonadotropin-releasing hormone secretion in vitro: correlation with perinatal exposure to sex steroids and induction of sexual precocity in vivo. Endocrinology 20040601
The unusual binding properties of the third distinct teleost estrogen receptor subtype ERbetaa are accompanied by highly conserved amino acid changes in the ligand binding domain. Endocrinology 20040601
Protein kinase A activation of estrogen receptor alpha transcription does not require proteasome activity and protects the receptor from ligand-mediated degradation. Endocrinology 20040601
Synergistic effects of ICI 182,780 on the cytotoxicity of cisplatin in cervical carcinoma cell lines. Cancer chemotherapy and pharmacology 20040601
Estrogen receptor-independent catechol estrogen binding activity: protein binding studies in wild-type, Estrogen receptor-alpha KO, and aromatase KO mice tissues. Biochemistry 20040601
Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells. Journal of molecular endocrinology 20040601
Distinct effects of the antiestrogen Faslodex on the stability of estrogen receptors-alpha and -beta in the breast cancer cell line MCF-7. Journal of molecular endocrinology 20040601
interferon regulatory factor-1 mediates the proapoptotic but not cell cycle arrest effects of the steroidal antiestrogen ICI 182,780 (faslodex, fulvestrant). Cancer research 20040601
Expression of iNOS gene in macrophages stimulated with 17beta-estradiol is regulated by free intracellular Ca2+. Biochemistry and cell biology = Biochimie et biologie cellulaire 20040601
Tamoxifen resistance by a conformational arrest of the estrogen receptor alpha after PKA activation in breast cancer. Cancer cell 20040601
Effects of 17beta-estradiol on in vitro maturation of pig oocytes in protein-free medium. The Journal of reproduction and development 20040601
A new MCF-7 breast cancer cell line resistant to the arzoxifene metabolite desmethylarzoxifene. Molecular and cellular endocrinology 20040531
Exposure to 4-tert-octylphenol, an environmentally persistent alkylphenol, enhances interleukin-4 production in T cells via NF-AT activation. Toxicology and applied pharmacology 20040515
Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) is a selective estrogen-response modulator in human breast cancer cells: gamma-linolenic acid antagonizes estrogen receptor-dependent transcriptional activity, transcriptionally represses estrogen receptor expression and synergistically enhances tamoxifen and ICI 182,780 (Faslodex) efficacy in human breast cancer cells. International journal of cancer 20040510
Short-chain fatty acids enhance nuclear receptor activity through mitogen-activated protein kinase activation and histone deacetylase inhibition. Proceedings of the National Academy of Sciences of the United States of America 20040504
The neuroprotective effects of estrogen in SK-N-SH neuroblastoma cell cultures. Neurochemistry international 20040501
Small nuclear RING finger protein expression during gonad development: regulation by gonadotropins and estrogen in the postnatal ovary. Endocrinology 20040501
Sequential versus combined treatment of human breast cancer cells with antiestrogens and the vitamin D analogue EB1089 and evaluation of predictive markers for vitamin D treatment. Breast cancer research and treatment 20040501
Estrogen receptor-mediated vascular responsiveness to nebivolol: a novel endothelium-related mechanism of therapeutic vasorelaxation. Journal of cardiovascular pharmacology 20040501
17beta-estradiol protects oligodendrocytes from cytotoxicity induced cell death. Journal of neurochemistry 20040501
Comparison of fulvestrant versus tamoxifen for the treatment of advanced breast cancer in postmenopausal women previously untreated with endocrine therapy: a multinational, double-blind, randomized trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040501
Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer. Cancer research 20040501
Estrogen up-regulates cyclooxygenase-2 via estrogen receptor in human uterine microvascular endothelial cells. Fertility and sterility 20040501
Isoflavones stimulate estrogen receptor-mediated core histone acetylation. Biochemical and biophysical research communications 20040423
Estradiol down-regulates CD36 expression in human breast cancer cells. Cancer letters 20040415
Re: Playing the old piano: another tune for endocrine therapy. Journal of the National Cancer Institute 20040407
Estradiol represses prolactin-induced expression of Na+/taurocholate cotransporting polypeptide in liver cells through estrogen receptor-alpha and signal transducers and activators of transcription 5a. Endocrinology 20040401
Re-expression of estrogen receptor alpha using a tetracycline-regulated gene expression system induced estrogen-mediated growth inhibition of the MDA-MB-231 breast cancer cell line. Biochemistry and cell biology = Biochimie et biologie cellulaire 20040401
Estrogen regulation in human breast cancer cells of new downstream gene targets involved in estrogen metabolism, cell proliferation and cell transformation. Journal of molecular endocrinology 20040401
Histone deacetylase inhibition and estrogen receptor alpha levels modulate the transcriptional activity of partial antiestrogens. Journal of molecular endocrinology 20040401
Identification of novel estrogen receptor alpha antagonists. The Journal of steroid biochemistry and molecular biology 20040401
Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation. International journal of cancer 20040320
Estrogenic activity of procymidone in rainbow trout (Oncorhynchus mykiss) hepatocytes: a possible mechanism of action. Chemico-biological interactions 20040315
Progestin-dependent induction of vascular endothelial growth factor in human breast cancer cells: preferential regulation by progesterone receptor B. Cancer research 20040315
Thombospondin-1 disrupts estrogen-induced endothelial cell proliferation and migration and its expression is suppressed by estradiol. Molecular cancer research : MCR 20040301
Transcriptional regulation of a BMP-6 promoter by estrogen receptor alpha. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040301
Fulvestrant: an oestrogen receptor antagonist with a novel mechanism of action. British journal of cancer 20040301
Fulvestrant: pharmacokinetics and pharmacology. British journal of cancer 20040301
Fulvestrant is an effective and well-tolerated endocrine therapy for postmenopausal women with advanced breast cancer: results from clinical trials. British journal of cancer 20040301
Fulvestrant and the sequential endocrine cascade for advanced breast cancer. British journal of cancer 20040301
Selective estrogen receptor modulators: discrimination of agonistic versus antagonistic activities by gene expression profiling in breast cancer cells. Cancer research 20040215
Estrogen elicits cytochrome P450--mediated flow-induced dilation of arterioles in NO deficiency: role of PI3K-Akt phosphorylation in genomic regulation. Circulation research 20040206
Overexpression of estrogen receptor-alpha gene suppresses gap junctional intercellular communication in endometrial carcinoma cells. Oncogene 20040205
Steroidal regulation of uterine edema and tissue inhibitors of metalloproteinase (TIMP)-3 messenger RNA expression is altered in TIMP-1-deficient mice. Biology of reproduction 20040201
Inhibition of estrogen receptor alpha expression and function in MCF-7 cells by kaempferol. Journal of cellular physiology 20040201
Involvement of protein kinase C-dependent mitogen-activated protein kinase p44/42 signaling pathway for cross-talk between estradiol and transforming growth factor-beta3 in increasing basic fibroblast growth factor in folliculostellate cells. Endocrinology 20040201
Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1. Molecular endocrinology (Baltimore, Md.) 20040201
Potent ligand-independent estrogen receptor activation by 3,3'-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways. Molecular endocrinology (Baltimore, Md.) 20040201
Estrogen preferentially promotes the differentiation of CD11c+ CD11b(intermediate) dendritic cells from bone marrow precursors. Journal of immunology (Baltimore, Md. : 1950) 20040201
Augmented endothelial nitric oxide synthase (eNOS) protein expression in human pregnant myometrium: possible involvement of eNOS promoter activation by estrogen via both estrogen receptor (ER)alpha and ERbeta. Molecular human reproduction 20040201
17beta-estradiol antagonizes cardiomyocyte hypertrophy by autocrine/paracrine stimulation of a guanylyl cyclase A receptor-cyclic guanosine monophosphate-dependent protein kinase pathway. Circulation 20040120
Estrogen-independent activation of erbBs signaling and estrogen receptor alpha in the mouse vagina exposed neonatally to diethylstilbestrol. Oncogene 20040115
Additive antitumour effect of the epidermal growth factor receptor tyrosine kinase inhibitor gefitinib (Iressa, ZD1839) and the antioestrogen fulvestrant (Faslodex, ICI 182,780) in breast cancer cells. British journal of cancer 20040112
Spreading the word, but not too thinly. Lancet (London, England) 20040110
Beneficial effects of estrogen treatment in the HLA-B27 transgenic rat model of inflammatory bowel disease. American journal of physiology. Gastrointestinal and liver physiology 20040101
Membrane estrogen receptor-dependent extracellular signal-regulated kinase pathway mediates acute activation of endothelial nitric oxide synthase by estrogen in uterine artery endothelial cells. Endocrinology 20040101
Comparison of proteomic and genomic analyses of the human breast cancer cell line T47D and the antiestrogen-resistant derivative T47D-r. Molecular & cellular proteomics : MCP 20040101
Increases in estrogen receptor-alpha concentration in breast cancer cells promote serine 118/104/106-independent AF-1 transactivation and growth in the absence of estrogen. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040101
Inhibition of HER1 signaling pathway enhances antitumor effect of endocrine therapy in breast cancer. Breast cancer (Tokyo, Japan) 20040101
Topical estrogen accelerates hair regrowth in mice after chemotherapy-induced alopecia by favoring the dystrophic catagen response pathway to damage. The Journal of investigative dermatology 20040101
BMP7/ActRIIB regulates estrogen-dependent apoptosis: new biomarkers for environmental estrogens. Journal of biochemical and molecular toxicology 20040101
Fulvestrant: a review of its use in hormone receptor-positive metastatic breast cancer in postmenopausal women with disease progression following antiestrogen therapy. Drugs 20040101
Aryl hydrocarbon receptor-mediated inhibition of LNCaP prostate cancer cell growth and hormone-induced transactivation. The Journal of steroid biochemistry and molecular biology 20040101
Fulvestrant for the treatment of advanced breast cancer in postmenopausal women: a Japanese study. Anticancer research 20040101
Pharmacokinetic profile of intramuscular fulvestrant in advanced breast cancer. Clinical pharmacokinetics 20040101
17beta-Estradiol promotes striatal medium size spiny neuronal maturation in vitro. Neuroendocrinology 20040101
Tamoxifen--what next? The oncologist 20040101
Conference report--cancer research 2004--top of the class March 27-March 31, 2004; Orlando, Florida. MedGenMed : Medscape general medicine 20040101
Dose- and photoperiod-dependent effects of 17beta-estradiol and the anti-estrogen ICI 182,780 on testicular structure, acceleration of spermatogenesis, and aromatase immunoexpression in immature bank voles. Acta histochemica 20040101
Plant 2-arylobenzofurans demonstrate a selective estrogen receptor modulator profile. Steroids 20040101
Fulvestrant ('Faslodex')--a new hormonal treatment for advanced breast cancer. European journal of oncology nursing : the official journal of European Oncology Nursing Society 20040101
Clinical experience with fulvestrant ('Faslodex'): a nurse's perspective. European journal of oncology nursing : the official journal of European Oncology Nursing Society 20040101
B-ring unsaturated estrogens: biological evaluation of 17alpha-Dihydroequilein and novel B-Nor-6-thiaequilenins as tissue selective estrogens. Bioorganic & medicinal chemistry letters 20031215
Estrogen modulates xanthine dehydrogenase/xanthine oxidase activity by a receptor-independent mechanism. Antioxidants & redox signaling 20031201
Resistance to different antiestrogens is caused by different multi-factorial changes and is associated with reduced expression of IGF receptor Ialpha. Endocrine-related cancer 20031201
An ICI 182,780-sensitive, membrane-related estrogen receptor contributes to estrogenic neuroprotective actions against amyloid-beta toxicity. Annals of the New York Academy of Sciences 20031201
Inhibitory action of ICI-182,780, an estrogen receptor antagonist, on BK(Ca) channel activity in cultured endothelial cells of human coronary artery. Biochemical pharmacology 20031115
Paradoxical action of fulvestrant in estradiol-induced regression of tamoxifen-stimulated breast cancer. Journal of the National Cancer Institute 20031105
The antiepidermal growth factor receptor agent gefitinib (ZD1839/Iressa) improves antihormone response and prevents development of resistance in breast cancer in vitro. Endocrinology 20031101
Steroid hormone regulation of the human kallikrein 10 (KLK10) gene in cancer cell lines and functional characterization of the KLK10 gene promoter. Clinica chimica acta; international journal of clinical chemistry 20031101
Octamethylcyclotetrasiloxane exhibits estrogenic activity in mice via ERalpha. Toxicology and applied pharmacology 20031101
2-methoxyestradiol strongly inhibits human uterine sarcomatous cell growth. Gynecologic oncology 20031101
Expression and mitogenic effect of fibroblast growth factor-9 in human endometriotic implant is regulated by aberrant production of estrogen. The Journal of clinical endocrinology and metabolism 20031101
Tamoxifen induces vasorelaxation via inhibition of mitogen-activated protein kinase in rat aortic smooth muscle. The Journal of veterinary medical science 20031101
The interaction of the steroidal antagonist faslodex and methotrexate. Cellular and molecular biology (Noisy-le-Grand, France) 20031101
Vascular ECE-1 mRNA expression decreases in response to estrogens. Life sciences 20031024
Fulvestrant: spreading the word, but not too thinly. Lancet (London, England) 20031018
AND-34/BCAR3, a GDP exchange factor whose overexpression confers antiestrogen resistance, activates Rac, PAK1, and the cyclin D1 promoter. Cancer research 20031015
17 beta-Estradiol inhibits angiotensin II activation of area postrema neurons. American journal of physiology. Heart and circulatory physiology 20031001
Various phosphorylation pathways, depending on agonist and antagonist binding to endogenous estrogen receptor alpha (ERalpha), differentially affect ERalpha extractability, proteasome-mediated stability, and transcriptional activity in human breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20031001
Equivalent single-dose pharmacokinetics of two different dosing methods of prolonged-release fulvestrant ('Faslodex') in postmenopausal women with advanced breast cancer. Cancer chemotherapy and pharmacology 20031001
Effect of 4-nonylphenol on cell proliferation and adipocyte formation in cultures of fully differentiated 3T3-L1 cells. Toxicological sciences : an official journal of the Society of Toxicology 20031001
17Beta-estradiol as a receptor-mediated cardioprotective agent. The Journal of pharmacology and experimental therapeutics 20031001
Tamoxifen and ICI 182,780 negatively influenced cardiac cell growth via an estrogen receptor-independent mechanism. Cardiovascular research 20031001
Fulvestrant in postmenopausal women with advanced breast cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20031001
Fulvestrant: an estrogen receptor antagonist that downregulates the estrogen receptor. Seminars in oncology 20031001
Synthetic estrogen-mediated activation of ERK 2 intracellular signaling molecule. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20031001
Regulation of uterine hsp90alpha, hsp72 and HSF-1 transcription in B6C3F1 mice by beta-estradiol and bisphenol A: involvement of the estrogen receptor and protein kinase C. Toxicology letters 20030930
Induction of p53 expression and function by estrogen in osteoblasts. Calcified tissue international 20030901
2-Methoxyestradiol exhibits a biphasic effect on VEGF-A in tumor cells and upregulation is mediated through ER-alpha: a possible signaling pathway associated with the impact of 2-ME2 on proliferative cells. Neoplasia (New York, N.Y.) 20030901
Enhanced estrogen receptor (ER) alpha, ERBB2, and MAPK signal transduction pathways operate during the adaptation of MCF-7 cells to long term estrogen deprivation. The Journal of biological chemistry 20030815
Expression of calcitonin gene-related peptide receptor components, calcitonin receptor-like receptor and receptor activity modifying protein 1, in the rat placenta during pregnancy and their cellular localization. Molecular human reproduction 20030801
Cadmium mimics the in vivo effects of estrogen in the uterus and mammary gland. Nature medicine 20030801
Regulation of ovarian primordial follicle assembly and development by estrogen and progesterone: endocrine model of follicle assembly. Endocrinology 20030801
17Beta-eEstradiol stimulates arachidonate release from human amnion-like WISH cells through a rapid mechanism involving a membrane receptor. Endocrinology 20030801
Alterations in the post-translational modification and intracellular trafficking of clusterin in MCF-7 cells during apoptosis. Cell death and differentiation 20030801
Both estrogen and raloxifene cause G1 arrest of vascular smooth muscle cells. The Journal of endocrinology 20030801
p27(Kip1) induces quiescence and growth factor insensitivity in tamoxifen-treated breast cancer cells. Cancer research 20030801
Dehydroepiandrosterone sulfate causes proliferation of estrogen receptor-positive breast cancer cells despite treatment with fulvestrant. Archives of surgery (Chicago, Ill. : 1960) 20030801
Expression of constitutively active Akt-3 in MCF-7 breast cancer cells reverses the estrogen and tamoxifen responsivity of these cells in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research 20030801
Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro. Biological & pharmaceutical bulletin 20030801
An antagonist of estrogen receptors blocks the induction of adult neurogenesis by insulin-like growth factor-I in the dentate gyrus of adult female rat. The European journal of neuroscience 20030801
Effect of estrogen and antiestrogens on the estrogen receptor content in the cochlea of ovariectomized rats. Hearing research 20030801
Effects of estriol on the proliferation and differentiation of human osteoblastic MG-63 cells. Endocrine research 20030801
[Switching off the estrogen effect and approaches to its correction]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20030801
Estrogenic and antiestrogenic regulation of MMP-2 and MMP-13 mRNA in RUCA-I endometrial tumor cells in vitro and in vivo. Cancer letters 20030730
Modulation of antioxidant enzyme expression and function by estrogen. Circulation research 20030725
Mutation of Leu-536 in human estrogen receptor-alpha alters the coupling between ligand binding, transcription activation, and receptor conformation. The Journal of biological chemistry 20030718
Fulvestrant versus anastrozole for the treatment of advanced breast carcinoma in postmenopausal women: a prospective combined analysis of two multicenter trials. Cancer 20030715
Inhibitory actions of genistein in human breast cancer (MCF-7) cells. Biochimica et biophysica acta 20030714
Antiestrogens are pro-apoptotic in normal human breast epithelial cells. International journal of cancer 20030710
Ligand-independent interactions of p160/steroid receptor coactivators and CREB-binding protein (CBP) with estrogen receptor-alpha: regulation by phosphorylation sites in the A/B region depends on other receptor domains. Molecular endocrinology (Baltimore, Md.) 20030701
Functional implications of antiestrogen induction of quinone reductase: inhibition of estrogen-induced deoxyribonucleic acid damage. Molecular endocrinology (Baltimore, Md.) 20030701
Expression of functional estrogen receptor beta in locus coeruleus-derived Cath.a cells. Endocrinology 20030701
New drugs 2003, part II. Nursing 20030701
Oestrogen receptor downregulation: an opportunity for extending the window of endocrine therapy in advanced breast cancer. Annals of oncology : official journal of the European Society for Medical Oncology 20030701
H-ras dependent estrogenic effects of epidermal growth factor in the estrogen-independent breast cancer cell line MDA-MB-231. Breast cancer research and treatment 20030701
Identification of estrogen receptor beta expression in Chinese hamster ovary (CHO) cells and comparison of estrogen-responsive gene transcription in cells adapted to serum-free media. The Journal of steroid biochemistry and molecular biology 20030701
Down-regulation of inducible nitric oxide synthase and tumor necrosis factor-alpha expression by bisphenol A via nuclear factor-kappaB inactivation in macrophages. Cancer letters 20030630
The differential effects of tamoxifen and ICI 182,780 on the reduction of Na+/K+ ATPase activity and spontaneous oscillations by 17beta-estradiol. The Chinese journal of physiology 20030630
Estrogens and ICI182,780 (Faslodex) modulate mitosis and cell death in immature cerebellar neurons via rapid activation of p44/p42 mitogen-activated protein kinase. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030615
Estradiol exacerbates hippocampal damage in a model of preterm infant brain injury. Endocrinology 20030601
Estrogen-like activity of metals in MCF-7 breast cancer cells. Endocrinology 20030601
An oestrogen membrane receptor participates in estradiol actions for the prevention of amyloid-beta peptide1-40-induced toxicity in septal-derived cholinergic SN56 cells. Journal of neurochemistry 20030601
Fulvestrant (Faslodex) versus anastrozole for the second-line treatment of advanced breast cancer in subgroups of postmenopausal women with visceral and non-visceral metastases: combined results from two multicentre trials. European journal of cancer (Oxford, England : 1990) 20030601
Modulation of the folate receptor alpha gene by the estrogen receptor: mechanism and implications in tumor targeting. Cancer research 20030601
A randomized, placebo-controlled, dose-ranging trial comparing fulvestrant with goserelin in premenopausal patients with uterine fibroids awaiting hysterectomy. Fertility and sterility 20030601
Estrogen-induced autonomic effects are mediated by NMDA and GABAA receptors in the parabrachial nucleus. Brain research 20030530
Impact of estrogen replacement on ventricular myocyte contractile function and protein kinase B/Akt activation. American journal of physiology. Heart and circulatory physiology 20030501
Estradiol rapidly activates Akt via the ErbB2 signaling pathway. Molecular endocrinology (Baltimore, Md.) 20030501
Domains of estrogen receptor alpha (ERalpha) required for ERalpha/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20030501
Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20030501
Resveratrol acts as an estrogen receptor (ER) agonist in breast cancer cells stably transfected with ER alpha. International journal of cancer 20030501
17beta-estradiol activates ICI 182,780-sensitive estrogen receptors and cyclic GMP-dependent thioredoxin expression for neuroprotection. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501
Time- and dose-related effects of estradiol and diethylstilbestrol on the morphology and function of the fetal rat testis in culture. Toxicological sciences : an official journal of the Society of Toxicology 20030501
Oxidative damage to human lens epithelial cells in culture: estrogen protection of mitochondrial potential, ATP, and cell viability. Investigative ophthalmology & visual science 20030501
Studies on the development of resistance to the pure antiestrogen Faslodex in three human breast cancer cell lines. The Journal of steroid biochemistry and molecular biology 20030501
Postmenopausal women who progress on fulvestrant ('Faslodex') remain sensitive to further endocrine therapy. Breast cancer research and treatment 20030501
Pharmacokinetics of a single dose of fulvestrant prolonged-release intramuscular injection in postmenopausal women awaiting surgery for primary breast cancer. Clinical therapeutics 20030501
Substance P in the uterine cervix, dorsal root ganglia and spinal cord during pregnancy and the effect of estrogen on SP synthesis. Peptides 20030501
De novo design, synthesis, and evaluation of novel nonsteroidal phenanthrene ligands for the estrogen receptor. Journal of medicinal chemistry 20030410
17-epiestriol, an estrogen metabolite, is more potent than estradiol in inhibiting vascular cell adhesion molecule 1 (VCAM-1) mRNA expression. The Journal of biological chemistry 20030404
Estrogen receptor, cyclic adenosine monophosphate, and protein kinase A are involved in the nongenomic pathway by which estradiol accelerates oviductal oocyte transport in cyclic rats. Biology of reproduction 20030401
Differential effects of natural and environmental estrogens on endothelin synthesis in bovine oviduct cells. Biology of reproduction 20030401
Uncoupling of 5-HT1A receptors in the brain by estrogens: regional variations in antagonism by ICI 182,780. Neuropharmacology 20030401
Induction of an estrogen-responsive reporter gene in rainbow trout hepatoma cells (RTH 149) at 11 or 18 degrees C. Environmental toxicology and chemistry 20030401
17Beta-estradiol and anti-estrogen ICI:compound 182,780 regulate expression of lipoprotein lipase and hormone-sensitive lipase in isolated subcutaneous abdominal adipocytes. Metabolism: clinical and experimental 20030401
The effect of estradiol in the striatum is blocked by ICI 182,780 but not tamoxifen: pharmacological and behavioral evidence. Neuroendocrinology 20030401
The display of sexual behaviors by female rats administered ICI 182,780. Hormones and behavior 20030401
The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20030301
Estrogen regulates tyrosine hydroxylase expression in the neonate mouse midbrain. Journal of neurobiology 20030301
Estradiol-induced vascular endothelial growth factor-A expression in breast tumor cells is biphasic and regulated by estrogen receptor-alpha dependent pathway. International journal of oncology 20030301
Estrogen activation of cyclic adenosine 5'-monophosphate response element-mediated transcription requires the extracellularly regulated kinase/mitogen-activated protein kinase pathway. Endocrinology 20030301
Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes. The Journal of pharmacology and experimental therapeutics 20030301
The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes. Molecular and cellular biology 20030301
Genistein inhibits vitamin D hydroxylases CYP24 and CYP27B1 expression in prostate cells. The Journal of steroid biochemistry and molecular biology 20030301
The effects of estradiol and selective estrogen receptor modulators on gene expression and messenger RNA stability in immortalized sheep endometrial stromal cells and human endometrial adenocarcinoma cells. The Journal of steroid biochemistry and molecular biology 20030301
Effect of antiestrogens and aromatase inhibitor on basal growth of the human breast cancer cell line MCF-7 in serum-free medium. The Journal of steroid biochemistry and molecular biology 20030301
Idoxifene and estradiol enhance antiapoptotic activity through estrogen receptor-beta in cultured rat hepatocytes. Digestive diseases and sciences 20030301
Differential SERM effects on corepressor binding dictate ERalpha activity in vivo. The Journal of biological chemistry 20030227
Modulation of estrogen receptor alpha function and stability by tamoxifen and a critical amino acid (Asp-538) in helix 12. The Journal of biological chemistry 20030227
The effects of the phytoestrogen, coumestrol, on gonadotropin-releasing hormone (GnRH) mRNA expression in GT1-7 GnRH neurones. Journal of neuroendocrinology 20030201
17alpha-estradiol-induced VEGF-A expression in rat pituitary tumor cells is mediated through ER independent but PI3K-Akt dependent signaling pathway. Biochemical and biophysical research communications 20030103
Estrogen receptor-alpha gene deficiency enhances androgen biosynthesis in the mouse Leydig cell. Endocrinology 20030101
Estrogen receptor-mediated neuroprotection from oxidative stress requires activation of the mitogen-activated protein kinase pathway. Endocrinology 20030101
Regulation of estrogen receptors and MMP-2 expression by estrogens in human retinal pigment epithelium. Investigative ophthalmology & visual science 20030101
Oestrogenic activity of benzylparaben. Journal of applied toxicology : JAT 20030101
Role of the estrogen antagonist ICI 182,780 in vessel assembly and apoptosis of endothelial cells. Ultrastructural pathology 20030101
Current status of selective estrogen receptor modulators (SERMs). Cancer journal (Sudbury, Mass.) 20030101
WISP-2 gene in human breast cancer: estrogen and progesterone inducible expression and regulation of tumor cell proliferation. Neoplasia (New York, N.Y.) 20030101
Fulvestrant antiestrogen for treatment of breast cancer. Clinical journal of oncology nursing 20030101
Ovarian steroids reduce apoptosis induced by trophic insufficiency in nerve growth factor-differentiated PC12 cells and axotomized rat facial motoneurons. Neuroscience 20030101
Estradiol inhibits atp-induced intracellular calcium concentration increase in dorsal root ganglia neurons. Neuroscience 20030101
The effects of estrogen, its antagonist ICI 182, 780, and interferon-tau on the expression of estrogen receptors and integrin alphaV beta 3 on cycle day 16 in bovine endometrium. Reproductive biology and endocrinology : RB&E 20030101
Effects of SERM (selective estrogen receptor modulator) treatment on growth and proliferation in the rat uterus. Reproductive biology and endocrinology : RB&E 20030101
Hormonal therapy for breast cancer: focus on fulvestrant. Clinical journal of oncology nursing 20030101
The antiestrogen ICI 182,780 induces early effects on the adult male mouse reproductive tract and long-term decreased fertility without testicular atrophy. Reproductive biology and endocrinology : RB&E 20030101
[Perspectives for the hormonal therapy of breast cancer]. Magyar onkologia 20030101
17beta-estradiol- and lipopolysaccharide-induced changes in nitric oxide, tumor necrosis factor-alpha and vascular endothelial growth factor release from RAW 264.7 macrophages. Gynecologic and obstetric investigation 20030101
Future directions in the endocrine therapy of breast cancer. Breast cancer research and treatment 20030101
Estrogen receptor beta in the paraventricular nucleus of hypothalamus regulates the neuroendocrine response to stress and is regulated by corticosterone. Neuroscience 20030101
Estrogenic compounds suppressed interferon-gamma production in mouse splenocytes through direct cell-cell interaction. In vitro cellular & developmental biology. Animal 20030101
The antiestrogen ICI 182,780 decreases the expression of estrogen receptor-alpha but has no effect on estrogen receptor-beta and androgen receptor in rat efferent ductules. Reproductive biology and endocrinology : RB&E 20030101
17 beta -estradiol-mediated vessel assembly and stabilization in tumor angiogenesis requires TGF beta and EGFR crosstalk. Angiogenesis 20030101
A phase I trial to assess the pharmacology of the new oestrogen receptor antagonist fulvestrant on the endometrium in healthy postmenopausal volunteers. British journal of cancer 20021202
Acute effects of 17beta -estradiol on femoral veins from adult gonadally intact and ovariectomized female pigs. American journal of physiology. Heart and circulatory physiology 20021201
Estradiol reduces F2alpha-isoprostane production in cultured human endothelial cells. American journal of physiology. Heart and circulatory physiology 20021201
Estrogenic and antiproliferative properties of soy sapogenols in human breast cancer cells in vitro. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021201
Modulation of estrogen receptor-dependent reporter construct activation and G0/G1-S-phase transition by polycyclic aromatic hydrocarbons in human breast carcinoma MCF-7 cells. Toxicological sciences : an official journal of the Society of Toxicology 20021201
Advances in endocrine therapy of metastatic breast cancer. The British journal of surgery 20021201
Isomer-specific activity of dichlorodyphenyltrichloroethane with estrogen receptor in adult and suckling estrogen reporter mice. Endocrinology 20021201
Constitutive overexpression of cyclin D1 but not cyclin E confers acute resistance to antiestrogens in T-47D breast cancer cells. Cancer research 20021201
Fulvestrant ('Faslodex')--a new treatment option for patients progressing on prior endocrine therapy. Endocrine-related cancer 20021201
Rapid uncoupling of serotonin-1A receptors in rat hippocampus by 17beta-estradiol in vitro requires protein kinases A and C. Neuroendocrinology 20021201
Stimulation of alkaline phosphatase activity in Ishikawa cells induced by various phytoestrogens and synthetic estrogens. The Journal of steroid biochemistry and molecular biology 20021201
Enhancing effects of estrogen on inhibitory avoidance performance may be in part independent of intracellular estrogen receptors in the hippocampus. Brain research 20021129
Estrogen receptor-dependent and estrogen receptor-independent pathways for tamoxifen and 4-hydroxytamoxifen-induced programmed cell death. The Journal of biological chemistry 20021122
Estrogen blocks 3-nitropropionic acid-induced Ca2+i increase and cell damage in cultured rat cerebral endothelial cells. Brain research 20021122
Involvement of G1/S cyclins in estrogen-independent proliferation of estrogen receptor-positive breast cancer cells. Oncogene 20021121
Cyr61 promotes breast tumorigenesis and cancer progression. Oncogene 20021121
Fulvestrant versus anastrozole as second-line treatment of advanced breast cancer in postmenopausal women. European journal of cancer (Oxford, England : 1990) 20021101
Selective oestrogen receptor downregulator. European journal of cancer (Oxford, England : 1990) 20021101
Immature uterotrophic assay of estrogenic compounds in rats given diets of different phytoestrogen content and the ovarian changes with ICI 182,780 or antide. Archives of toxicology 20021101
Effects of 17 alpha-methyltestosterone on uterine morphology and heat shock protein expression are mediated through estrogen and androgen receptors. The Journal of steroid biochemistry and molecular biology 20021101
A role for TGF-beta in estrogen and retinoid mediated regulation of the nuclear receptor coactivator AIB1 in MCF-7 breast cancer cells. Oncogene 20021017
Two antiestrogens affect differently chromatin remodeling of trefoil factor 1 (pS2) gene and the fate of estrogen receptor in MCF7 cells. Biochimica et biophysica acta 20021011
Estrogenicity of organophosphorus and pyrethroid pesticides. Journal of toxicology and environmental health. Part A 20021011
Calcitonin expression in rat anterior pituitary gland is regulated by ovarian steroid hormones. Endocrinology 20021001
Expression and regulation of calcitonin gene-related Peptide receptor in rat placentas. Biology of reproduction 20021001
A new estrogen receptor antagonist--an overview of available data. Breast cancer research and treatment 20021001
A novel mechanism for endocrine-disrupting effects of polychlorinated biphenyls: direct effects on gonadotropin-releasing hormone neurones. Journal of neuroendocrinology 20021001
In vitro antiestrogenic effects of aryl methyl sulfone metabolites of polychlorinated biphenyls and 2,2-bis(4-chlorophenyl)-1,1-dichloroethene on 17beta-estradiol-induced gene expression in several bioassay systems. Toxicological sciences : an official journal of the Society of Toxicology 20021001
Structure and regulation of expression of the mouse GH receptor. The Journal of endocrinology 20021001
Effects of resveratrol-related hydroxystilbenes on the nitric oxide production in macrophage cells: structural requirements and mechanism of action. Life sciences 20020913
Bisphenol A stimulates NO synthesis through a non-genomic estrogen receptor-mediated mechanism in mouse endothelial cells. Toxicology letters 20020905
Genistein action in the prepubertal mammary gland in a chemoprevention model. Carcinogenesis 20020901
Double-blind, randomized trial comparing the efficacy and tolerability of fulvestrant versus anastrozole in postmenopausal women with advanced breast cancer progressing on prior endocrine therapy: results of a North American trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020815
Fulvestrant, formerly ICI 182,780, is as effective as anastrozole in postmenopausal women with advanced breast cancer progressing after prior endocrine treatment. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020815
Estradiol stimulates GDNF expression in developing hypothalamic neurons. Endocrinology 20020801
Interactions of ATP, oestradiol, genistein and the anti-oestrogens, faslodex (ICI 182780) and tamoxifen, with the human erythrocyte glucose transporter, GLUT1. The Biochemical journal 20020801
Intracellular pathways mediating estrogen-induced cholangiocyte proliferation in the rat. Hepatology (Baltimore, Md.) 20020801
The pure anti-oestrogen ICI 182,780 (Faslodex) activates large conductance Ca(2+)-activated K(+) channels in smooth muscle. British journal of pharmacology 20020801
Targeting of SWI/SNF chromatin remodelling complexes to estrogen-responsive genes. The EMBO journal 20020801
Identification of a negative regulatory surface within estrogen receptor alpha provides evidence in support of a role for corepressors in regulating cellular responses to agonists and antagonists. Molecular endocrinology (Baltimore, Md.) 20020801
Gene expression profiles with activation of the estrogen receptor alpha-selective estrogen receptor modulator complex in breast cancer cells expressing wild-type estrogen receptor. Cancer research 20020801
Estrogen-like activity of ginsenoside Rg1 derived from Panax notoginseng. The Journal of clinical endocrinology and metabolism 20020801
Estrogen represses whereas the estrogen-antagonist ICI 182780 stimulates placental CRH gene expression. The Journal of clinical endocrinology and metabolism 20020801
Molecular changes associated with the acquisition of oestrogen hypersensitivity in MCF-7 breast cancer cells on long-term oestrogen deprivation. The Journal of steroid biochemistry and molecular biology 20020801
Phosphorylation of human estrogen receptor alpha at serine 118 by two distinct signal transduction pathways revealed by phosphorylation-specific antisera. Oncogene 20020725
Fulvestrant (faslodex) for advanced breast cancer. The Medical letter on drugs and therapeutics 20020722
Estradiol enhances and estriol inhibits the expression of CYP1A1 induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in a mouse ovarian cancer cell line. Toxicology 20020715
Antiestrogen ICI 182,780 decreases proliferation of insulin-like growth factor I (IGF-I)-treated MCF-7 cells without inhibiting IGF-I signaling. Cancer research 20020715
Inhibition of progesterone-induced VEGF production in human breast cancer cells by the pure antiestrogen ICI 182,780. Cancer letters 20020708
2-Methoxyestradiol inhibits proliferation and induces apoptosis independently of estrogen receptors alpha and beta. Cancer research 20020701
The effect of second-line antiestrogen therapy on breast tumor growth after first-line treatment with the aromatase inhibitor letrozole: long-term studies using the intratumoral aromatase postmenopausal breast cancer model. Clinical cancer research : an official journal of the American Association for Cancer Research 20020701
Regulation of matrix metalloproteinase expression by estrogen in fibroblasts that are derived from the pelvic floor. American journal of obstetrics and gynecology 20020701
Effects of selective estrogen receptor modulators (SERMs) on coactivator nuclear receptor (NR) box binding to estrogen receptors. Molecular genetics and metabolism 20020701
New alternative to tamoxifen. Harvard women's health watch 20020701
Ligand-independent activation of steroid receptors. Domestic animal endocrinology 20020701
Organochlorine pesticides directly regulate gonadotropin-releasing hormone gene expression and biosynthesis in the GT1-7 hypothalamic cell line. Molecular and cellular endocrinology 20020628
Suppression of inducible nitric oxide synthase and tumor necrosis factor-alpha expression by 4-nonylphenol in macrophages. Biochemical and biophysical research communications 20020621
Association of interferon regulatory factor-1, nucleophosmin, nuclear factor-kappaB, and cyclic AMP response element binding with acquired resistance to Faslodex (ICI 182,780). Cancer research 20020615
Triphenylethylene antiestrogen-induced acute relaxation of mouse duodenal muscle. Possible involvement of Ca2+ channels. European journal of pharmacology 20020612
Gene expression profiling of testosterone and estradiol-17 beta-induced prostatic dysplasia in Noble rats and response to the antiestrogen ICI 182,780. Endocrinology 20020601
ER function in the adult male rat: short- and long-term effects of the antiestrogen ICI 182,780 on the testis and efferent ductules, without changes in testosterone. Endocrinology 20020601
Mechanisms of growth arrest by c-myc antisense oligonucleotides in MCF-7 breast cancer cells: implications for the antiproliferative effects of antiestrogens. Cancer research 20020601
Estrogen increases endothelial nitric oxide synthase via estrogen receptors in rat cerebral blood vessels: effect preserved after concurrent treatment with medroxyprogesterone acetate or progesterone. Stroke 20020601
Direct actions of estradiol on the anterior pituitary gland are required for hypothalamus-dependent lactotrope proliferation and secretory surges of luteinizing hormone but not of prolactin in female rats. Neuroendocrinology 20020601
Modulation of epidermal growth factor receptor in endocrine-resistant, estrogen-receptor-positive breast cancer. Annals of the New York Academy of Sciences 20020601
A review of selective estrogen receptor modulators in the treatment of breast and endometrial cancer. Seminars in oncology 20020601
Concept evaluation: an assay for receptor-mediated and biochemical antiestrogens using pubertal rats. Regulatory toxicology and pharmacology : RTP 20020601
C-myc gene expression alone is sufficient to confer resistance to antiestrogen in human breast cancer cells. International journal of cancer 20020501
Nongenomic regulation of the kinetics of exocytosis by estrogens. The Journal of pharmacology and experimental therapeutics 20020501
Oestrogen action on the myocardium in vivo: specific and permissive for angiotensin-converting enzyme inhibition. Journal of hypertension 20020501
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. The Journal of biological chemistry 20020419
Effect of prolonged hydroxytamoxifen treatment of MCF-7 cells on mitogen activated kinase cascade. International journal of cancer 20020410
High glucose abolishes the antiproliferative effect of 17beta-estradiol in human vascular smooth muscle cells. American journal of physiology. Endocrinology and metabolism 20020401
Ligand-specific regulation of proteasome-mediated proteolysis of estrogen receptor-alpha. American journal of physiology. Endocrinology and metabolism 20020401
Estrogen attenuates the cardiovascular and ventilatory responses to central command in cats. Journal of applied physiology (Bethesda, Md. : 1985) 20020401
Differential effects of sarcolemmal and mitochondrial K(ATP) channels activated by 17 beta-estradiol on reperfusion arrhythmias and infarct sizes in canine hearts. The Journal of pharmacology and experimental therapeutics 20020401
Estrogen receptor isoform-specific induction of progesterone receptors in human osteoblasts. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020401
Down-regulation of osteoclast differentiation by daidzein via caspase 3. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020401
Human osteoblasts' proliferative responses to strain and 17beta-estradiol are mediated by the estrogen receptor and the receptor for insulin-like growth factor I. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020401
17-beta-oestradiol-induced vasorelaxation in vitro is mediated by eNOS through hsp90 and akt/pkb dependent mechanism. British journal of pharmacology 20020401
Tamoxifen elicits its anti-estrogen effects in growth plate chondrocytes by inhibiting protein kinase C. The Journal of steroid biochemistry and molecular biology 20020401
Reciprocal regulation by estradiol 17-beta of ezrin and cadherin-catenin complexes in pituitary GH3 cells. Endocrine 20020401
Fulvestrant (Faslodex): current status in the therapy of breast cancer. Expert review of anticancer therapy 20020401
Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk. The Journal of biological chemistry 20020308
Comparative effects of testosterone propionate, oestradiol benzoate, ICI 182,780, tamoxifen and raloxifene on hypothalamic differentiation in the female rat. The Journal of endocrinology 20020301
Ligand-selective interactions of ER detected in living cells by fluorescence resonance energy transfer. Molecular endocrinology (Baltimore, Md.) 20020301
Stanniocalcin 2 is an estrogen-responsive gene coexpressed with the estrogen receptor in human breast cancer. Cancer research 20020301
The estrogen receptor ligand ICI 182,780 does not impair the bone-sparing effects of testosterone in the young orchidectomized rat model. Calcified tissue international 20020301
Estradiol stimulates gene expression of norepinephrine biosynthetic enzymes in rat locus coeruleus. Neuroendocrinology 20020301
Effects of dietary phytoestrogens in vivo and in vitro in rainbow trout and Siberian sturgeon: interests and limits of the in vitro studies of interspecies differences. General and comparative endocrinology 20020301
Effects of flavonoid phytochemicals on cortisol production and on activities of steroidogenic enzymes in human adrenocortical H295R cells. The Journal of steroid biochemistry and molecular biology 20020301
The cyclin-dependent kinase inhibitor p21WAF1/Cip1 is an antiestrogen-regulated inhibitor of Cdk4 in human breast cancer cells. The Journal of biological chemistry 20020215
Receptor-mediated ethinylestradiol-induced oxidative DNA damage in rat testicular cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020201
Fulvestrant. Expert opinion on investigational drugs 20020201
2-methoxyestradiol induces interferon gene expression and apoptosis in osteosarcoma cells. Bone 20020201
Fulvestrant (AstraZeneca). Current opinion in investigational drugs (London, England : 2000) 20020201
Expression and regulation of Cyr61 in human breast cancer cell lines. Oncogene 20020131
Cooperative coactivation of estrogen receptor alpha in ZR-75 human breast cancer cells by SNURF and TATA-binding protein. The Journal of biological chemistry 20020125
Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta. Science (New York, N.Y.) 20020118
Functional role of estrogen in pituitary tumor pathogenesis. The Journal of clinical investigation 20020115
A+U-rich-element RNA-binding factor 1/heterogeneous nuclear ribonucleoprotein D gene expression is regulated by oestrogen in the rat uterus. The Biochemical journal 20020101
Estrogen action via the G protein-coupled receptor, GPR30: stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis. Molecular endocrinology (Baltimore, Md.) 20020101
Phytoestrogen genistein stimulates the production of osteoprotegerin by human trabecular osteoblasts. Journal of cellular biochemistry 20020101
Oestrogenic activity of parabens in MCF7 human breast cancer cells. The Journal of steroid biochemistry and molecular biology 20020101
Effects of the environmental estrogens bisphenol A, o,p'-DDT, p-tert-octylphenol and coumestrol on apoptosis induction, cell proliferation and the expression of estrogen sensitive molecular parameters in the human breast cancer cell line MCF-7. The Journal of steroid biochemistry and molecular biology 20020101
Toxicity of antiestrogens. The breast journal 20020101
Fulvestrant: clinical application of an estrogen receptor downregulator. Clinical therapeutics 20020101
Identification and characterization of a negative regulatory element within the epidermal growth factor receptor gene first intron in hormone-dependent breast cancer cells. Journal of cellular biochemistry 20020101
The effect of antiestrogens on TGF-beta-mediated chemotaxis of human breast cancer cells. Anticancer research 20020101
Reduction of post injury neointima formation due to 17beta-estradiol and phytoestrogen treatment is not influenced by the pure synthetic estrogen receptor antagonist ICI 182,780 in vitro. BMC cardiovascular disorders 20020101
Critical parameters in the MCF-7 cell proliferation bioassay (E-Screen). Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20020101
Fulvestrant, an estrogen receptor downregulator, reduces cell turnover index more effectively than tamoxifen. Anticancer research 20020101
New treatment for advanced breast cancer. FDA consumer 20020101
In vitro regulation of vascular endothelial growth factor by estrogens and antiestrogens in estrogen-receptor positive breast cancer. Breast cancer (Tokyo, Japan) 20020101
Oestrogenic activity of isobutylparaben in vitro and in vivo. Journal of applied toxicology : JAT 20020101
Inhibition of low-density lipoprotein oxidation by the pure antiestrogens ICI 182780 and EM-652 (SCH 57068). Menopause (New York, N.Y.) 20020101
Inhibition of E2-induced expression of BRCA1 by persistent organochlorines. Breast cancer research : BCR 20020101
FDA drug approval summaries: fulvestrant. The oncologist 20020101
Estrogenic down-regulation of protein tyrosine phosphatase gamma (PTP gamma) in human breast is associated with estrogen receptor alpha. Anticancer research 20020101
Induction of endothelial nitric-oxide synthase phosphorylation by the raloxifene analog LY117018 is differentially mediated by Akt and extracellular signal-regulated protein kinase in vascular endothelial cells. The Journal of biological chemistry 20011214
Selected contribution: Effects of gender on reduced-size liver ischemia and reperfusion injury. Journal of applied physiology (Bethesda, Md. : 1985) 20011201
Identification of novel oestrogen receptor target genes in human ZR75-1 breast cancer cells by expression profiling. Journal of molecular endocrinology 20011201
Stimulation of vascular protein synthesis by activation of oestrogen receptor beta. The Journal of endocrinology 20011201
Estrogen increases CD40 ligand expression in T cells from women with systemic lupus erythematosus. The Journal of rheumatology 20011201
Modulation of aromatase expression in human breast tissue. The Journal of steroid biochemistry and molecular biology 20011201
Adaptive hypersensitivity to estradiol: potential mechanism for secondary hormonal responses in breast cancer patients. The Journal of steroid biochemistry and molecular biology 20011201
Faslodex (ICI 182, 780), a novel estrogen receptor downregulator--future possibilities in breast cancer. The Journal of steroid biochemistry and molecular biology 20011201
Prospects for combining hormonal and nonhormonal growth factor inhibition. Clinical cancer research : an official journal of the American Association for Cancer Research 20011201
Estrogen-induced recovery of autonomic function after middle cerebral artery occlusion in male rats. American journal of physiology. Regulatory, integrative and comparative physiology 20011101
Estrogen regulation of ion transporter messenger RNA levels in mouse efferent ductules are mediated differentially through estrogen receptor (ER) alpha and ER beta. Biology of reproduction 20011101
Adult tissue angiogenesis: evidence for negative regulation by estrogen in the uterus. Molecular endocrinology (Baltimore, Md.) 20011101
Acute gender-specific hemodynamic and inotropic effects of 17beta-estradiol on rats. Hypertension (Dallas, Tex. : 1979) 20011101
Oestrogen-mediated suppression of tumour necrosis factor alpha-induced apoptosis in MCF-7 cells: subversion of Bcl-2 by anti-oestrogens. The Journal of steroid biochemistry and molecular biology 20011101
ICI 182,780 (Fulvestrant)--the first oestrogen receptor down-regulator--current clinical data. British journal of cancer 20011101
A vision for the future? British journal of cancer 20011101
Estrogen stimulates brain-derived neurotrophic factor expression in embryonic mouse midbrain neurons through a membrane-mediated and calcium-dependent mechanism. Journal of neuroscience research 20011015
Effects of beta-estradiol and bisphenol A on heat shock protein levels and localization in the mouse uterus are antagonized by the antiestrogen ICI 182,780. Toxicological sciences : an official journal of the Society of Toxicology 20011001
Co-administration of finasteride and the pure anti-oestrogen ICI 182,780 act synergistically in modulating the IGF system in rat prostate. The Journal of endocrinology 20011001
Synergistic activation of functional estrogen receptor (ER)-alpha by DNA methyltransferase and histone deacetylase inhibition in human ER-alpha-negative breast cancer cells. Cancer research 20011001
Novel antitumor effect of estradiol in athymic mice injected with a T47D breast cancer cell line overexpressing protein kinase Calpha. Clinical cancer research : an official journal of the American Association for Cancer Research 20011001
A new antiestrogen, 2-(4-hydroxy-phenyl)-3-methyl-1-[4-(2-piperidin-1-yl-ethoxy)-benzyl]-1H-indol-5-ol hydrochloride (ERA-923), inhibits the growth of tamoxifen-sensitive and -resistant tumors and is devoid of uterotropic effects in mice and rats. Clinical cancer research : an official journal of the American Association for Cancer Research 20011001
Hypoxia reduces hormone responsiveness of human breast cancer cells. Japanese journal of cancer research : Gann 20011001
Comparison of the short-term biological effects of 7alpha-[9-(4,4,5,5,5-pentafluoropentylsulfinyl)-nonyl]estra-1,3,5, (10)-triene-3,17beta-diol (Faslodex) versus tamoxifen in postmenopausal women with primary breast cancer. Cancer research 20010915
Comparison of an array of in vitro assays for the assessment of the estrogenic potential of natural and synthetic estrogens, phytoestrogens and xenoestrogens. Toxicology 20010914
Assessment of the oestrogenic activity of the contraceptive progestin levonorgestrel and its non-phenolic metabolites. European journal of pharmacology 20010914
Hepatic stellate cells contain the functional estrogen receptor beta but not the estrogen receptor alpha in male and female rats. Biochemical and biophysical research communications 20010907
Effects of chronic estrogen-receptor blockade on ovine perinatal pulmonary circulation. American journal of physiology. Heart and circulatory physiology 20010901
Effects of dietary phytoestrogen on global myocardial ischemia-reperfusion injury in isolated female rat hearts. American journal of physiology. Heart and circulatory physiology 20010901
Temporal effects of 17beta-estradiol on caveolin-1 mRNA and protein in bovine aortic endothelial cells. American journal of physiology. Heart and circulatory physiology 20010901
Infertility and testicular atrophy in the antiestrogen-treated adult male rat. Biology of reproduction 20010901
Enhancement of collagen-induced arthritis in female mice by estrogen receptor blockage. Arthritis and rheumatism 20010901
Inhibitory effect of 17beta-estradiol in the parabrachial nucleus is mediated by GABA. Brain research 20010824
Estrogen prevents destabilization of endothelial nitric oxide synthase mRNA induced by tumor necrosis factor alpha through estrogen receptor mediated system. Life sciences 20010824
Activation of estrogen receptor beta is a prerequisite for estrogen-dependent upregulation of nitric oxide synthases in neonatal rat cardiac myocytes. FEBS letters 20010803
Induction of mammary epithelial cell differentiation and inhibition of dimethylbenz(A)anthracene-induced mammary tumour by co-administration of a pure antiestrogen ICI 182,780 and testosterone enanthate. International journal of oncology 20010801
S-adenosylmethionine decarboxylase overexpression reduces invasiveness and tumorigenicity in nude mice of MCF-7 breast cancer cells. International journal of oncology 20010801
Hyperactivation of MAPK induces loss of ERalpha expression in breast cancer cells. Molecular endocrinology (Baltimore, Md.) 20010801
Inhibition of insulin-like growth factor signaling pathways in mammary gland by pure antiestrogen ICI 182,780. Clinical cancer research : an official journal of the American Association for Cancer Research 20010801
Molecular identification of potential selective estrogen receptor modulator (SERM) like properties of phytoestrogens in the human breast cancer cell line MCF-7. Planta medica 20010801
Estrogen regulation of human osteoblast function is determined by the stage of differentiation and the estrogen receptor isoform. Journal of cellular biochemistry 20010801
Mechanisms of estrogen receptor action in the myocardium. Rapid gene activation via the ERK1/2 pathway and serum response elements. The Journal of biological chemistry 20010727
Estrogen protects neuronal cells from amyloid beta-induced apoptotic cell death. Neuroreport 20010703
Cell-transforming activity and estrogenicity of bisphenol-A and 4 of its analogs in mammalian cells. International journal of cancer 20010701
Enhanced epidermal growth factor receptor signaling in MCF7 breast cancer cells after long-term culture in the presence of the pure antiestrogen ICI 182,780 (Faslodex). Endocrinology 20010701
Induction of UO-44 gene expression by tamoxifen in the rat uterus and ovary. Endocrinology 20010701
Production of steroids by human ovarian surface epithelial cells in culture: possible role of progesterone as growth inhibitor. Gynecologic oncology 20010701
[Developments of hormonal agents for breast cancer]. Gan to kagaku ryoho. Cancer & chemotherapy 20010701
Differential activation of wild-type and variant forms of estrogen receptor alpha by synthetic and natural estrogenic compounds using a promoter containing three estrogen-responsive elements. The Journal of steroid biochemistry and molecular biology 20010701
Estrogenic influence on the regulation of hepatic estrogen receptor-alpha and serum level of angiotensinogen in female rats. The Journal of steroid biochemistry and molecular biology 20010701
Induction of apoptosis in mammary gland by a pure anti-estrogen ICI 182780. Breast cancer research and treatment 20010701
Estrogen receptor (ER)alpha and ERbeta exhibit unique pharmacologic properties when coupled to activation of the mitogen-activated protein kinase pathway. Endocrinology 20010601
Identification and implantation stage-specific expression of an interferon-alpha-regulated gene in human and rat endometrium. Endocrinology 20010601
Cyr61, a member of the CCN family, is required for MCF-7 cell proliferation: regulation by 17beta-estradiol and overexpression in human breast cancer. Endocrinology 20010601
Phytoestrogens restore nitric oxide-mediated relaxation in isolated pulmonary arteries from chronically hypoxic rats. The Journal of pharmacology and experimental therapeutics 20010601
Estradiol-regulated expression of the immunophilins cyclophilin 40 and FKBP52 in MCF-7 breast cancer cells. Biochemical and biophysical research communications 20010601
Estrogen and neuroinflammation. Urology 20010601
The Src signaling pathway regulates osteoclast lysosomal enzyme secretion and is rapidly modulated by estrogen. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010601
ICI 182,780 acts as a partial agonist and antagonist of estradiol effects in specific cells of the sheep uterus. The Journal of steroid biochemistry and molecular biology 20010601
Effects of estrogen on leptin gene promoter activation in MCF-7 breast cancer and JEG-3 choriocarcinoma cells: selective regulation via estrogen receptors alpha and beta. Molecular and cellular endocrinology 20010515
Dexamethasone blocks antioestrogen- and oxidant-induced death of pituitary tumour cells. The Journal of endocrinology 20010501
Effects of acute stanozolol treatment on puberty in female rats. Biology of reproduction 20010501
Differential regulation of retinoblastoma protein by hormonal and antihormonal agents in T47D breast cancer cells. The Journal of steroid biochemistry and molecular biology 20010501
Antagonism of oestrogen action in human breast and endometrial cells in vitro: potential novel antitumour agents. Cancer chemotherapy and pharmacology 20010501
Estrogen receptor binding to DNA is not required for its activity through the nonclassical AP1 pathway. The Journal of biological chemistry 20010427
Breast cancer. Cyr61 is overexpressed, estrogen-inducible, and associated with more advanced disease. The Journal of biological chemistry 20010427
Neuroprotective effects of estrogen against beta-amyloid toxicity are mediated by estrogen receptors in cultured neuronal cells. Neuroscience letters 20010413
Tamoxifen inhibits nerve growth factor-induced proliferation of the human breast cancerous cell line MCF-7. Cancer research 20010401
Relaxant effects of 17-beta-estradiol in cerebral arteries through Ca(2+) entry inhibition. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010401
Androgen-accelerated bone maturation in mice is not attenuated by Faslodex, an estrogen receptor blocker. Bone 20010401
Synthetic estrogens-mediated activation of JNK intracellular signaling molecule. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20010401
Estrogen prevents the lipopolysaccharide-induced inflammatory response in microglia. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010315
17-beta estradiol elicits an autocrine leiomyoma cell proliferation: evidence for a stimulation of protein kinase-dependent pathway. Journal of cellular physiology 20010301
Systemic ICI 182,780 alters the display of sexual behaviors in the female rat. Hormones and behavior 20010301
Estrogens act in rat hippocampus and frontal cortex to produce rapid, receptor-mediated decreases in serotonin 5-HT(1A) receptor function. Neuroendocrinology 20010301
Dehydroepiandrosterone stimulates proliferation and gene expression in MCF-7 cells after conversion to estradiol. Molecular and cellular endocrinology 20010227
Testosterone inhibits osteoclast formation stimulated by parathyroid hormone through androgen receptor. FEBS letters 20010223
Transcriptional activation of heat shock protein 27 gene expression by 17beta-estradiol and modulation by antiestrogens and aryl hydrocarbon receptor agonists. Journal of molecular endocrinology 20010201
Role of androgens in the growth of endometrial carcinoma: an in vivo animal model. American journal of obstetrics and gynecology 20010201
Proliferative effects of combination estrogen and progesterone replacement therapy on the normal postmenopausal mammary gland in a murine model. American journal of obstetrics and gynecology 20010201
Estradiol metabolites inhibit endothelin synthesis by an estrogen receptor-independent mechanism. Hypertension (Dallas, Tex. : 1979) 20010201
Effects of estradiol and its metabolites on glomerular endothelial nitric oxide synthesis and mesangial cell growth. Hypertension (Dallas, Tex. : 1979) 20010201
The phytoestrogen alpha-zearalenol reverses endothelial dysfunction induced by oophorectomy in rats. Laboratory investigation; a journal of technical methods and pathology 20010201
Regulation of progesterone receptors and decidualization in uterine stroma of the estrogen receptor-alpha knockout mouse. Biology of reproduction 20010101
FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent. Nature cell biology 20010101
The PlA polymorphism of glycoprotein IIIa functions as a modifier for the effect of estrogen on platelet aggregation. Archives of pathology & laboratory medicine 20010101
Inhibition of volume-regulated anion channels in cultured endothelial cells by the anti-oestrogens clomiphene and nafoxidine. British journal of pharmacology 20010101
The Twenty-third Annual San Antonio Breast Cancer Symposium. Current medical research and opinion 20010101
Relationship between expression of coactivators and corepressors of hormone receptors and resistance of ovarian cancers to growth regulation by steroid hormones. Journal of the Society for Gynecologic Investigation 20010101
Estrogen downregulates the number of caveolae and the level of caveolin in uterine smooth muscle. Cell biology international 20010101
Effects of oestradiol and the oestrogen antagonist Ici 182,780 on the delayed type hypersensitivity (DTH) index and on serum levels of IgM and IgG in ovariectomised Balb/C and MRL/Mp-Lpr/Lpr mice, a model of systemic lupus erythematosus (SLE). Autoimmunity 20010101
Endometrial effects of pure antiestrogens. Tumori 20010101
Pure antiestrogens and breast cancer. Current medical research and opinion 20010101
Isoflavones inhibit proliferation of ovarian cancer cells in vitro via an estrogen receptor-dependent pathway. Nutrition and cancer 20010101
TCDD elevates erbB2 expression and signaling in T47D cells by reversing serum potentiation of estrogen receptor activity, independent of estrogen levels and enhanced ER down-regulation. Molecular and cellular endocrinology 20001222
Effects of arsenite on estrogen receptor-alpha expression and activity in MCF-7 breast cancer cells. Endocrinology 20001001
Relative binding affinity does not predict biological response to xenoestrogens in rat endometrial adenocarcinoma cells. The Journal of steroid biochemistry and molecular biology 20001001
WISP-2 as a novel estrogen-responsive gene in human breast cancer cells. Biochemical and biophysical research communications 20000818
Estrogenic effects of organochlorine pesticides on uterine leiomyoma cells in vitro. Toxicological sciences : an official journal of the Society of Toxicology 20000401
A metabolite of methoxychlor, 2,2-bis(p-hydroxyphenyl)-1,1, 1-trichloroethane, reduces testosterone biosynthesis in rat leydig cells through suppression of steady-state messenger ribonucleic acid levels of the cholesterol side-chain cleavage enzyme. Biology of reproduction 20000301
Proteinase inhibitor 9, an inhibitor of granzyme B-mediated apoptosis, is a primary estrogen-inducible gene in human liver cells. The Journal of biological chemistry 20000225
High concentrations of bisphenol A induce cell growth and prolactin secretion in an estrogen-responsive pituitary tumor cell line. Toxicology and applied pharmacology 20000201
Molecular analysis of the inhibition of monocyte chemoattractant protein-1 gene expression by estrogens and xenoestrogens in MCF-7 cells. Endocrinology 20000101
Comparative analyses of mechanistic differences among antiestrogens. Endocrinology 19991201
The aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT) heterodimer interacts with naturally occurring estrogen response elements. Molecular and cellular endocrinology 19991125
Estrogen directly respresses gonadotropin-releasing hormone (GnRH) gene expression in estrogen receptor-alpha (ERalpha)- and ERbeta-expressing GT1-7 GnRH neurons. Endocrinology 19991101
Effects of environmental estrogens on tumor necrosis factor alpha-mediated apoptosis in MCF-7 cells. Carcinogenesis 19991101
Transcriptional activation of c-fos protooncogene by 17beta-estradiol: mechanism of aryl hydrocarbon receptor-mediated inhibition. Molecular endocrinology (Baltimore, Md.) 19990901
Methoxychlor stimulates estrogen-responsive messenger ribonucleic acids in mouse uterus through a non-estrogen receptor (non-ER) alpha and non-ER beta mechanism. Endocrinology 19990801
Expression of CYP1A1 and CYP1B1 depends on cell-specific factors in human breast cancer cell lines: role of estrogen receptor status. Carcinogenesis 19990601
Estrogenicity of bisphenol A in a human endometrial carcinoma cell line. Molecular and cellular endocrinology 19990425
Perinatal exposure to estrogenic compounds and the subsequent effects on the prostate of the adult rat: evaluation of inflammation in the ventral and lateral lobes. Reproductive toxicology (Elmsford, N.Y.) 19990101
Aryl hydrocarbon receptor-mediated antiestrogenicity in MCF-7 cells: modulation of hormone-induced cell cycle enzymes. Archives of biochemistry and biophysics 19980815
Differential spatiotemporal regulation of lactoferrin and progesterone receptor genes in the mouse uterus by primary estrogen, catechol estrogen, and xenoestrogen. Endocrinology 19980601
Estradiol induces C-type natriuretic peptide gene expression in mouse uterus. The American journal of physiology 19971201
Effect of toxaphene on estrogen receptor functions in human breast cancer cells. Carcinogenesis 19970801
Estrogen-induced cyclin D1 and D3 gene expressions during mouse uterine cell proliferation in vivo: differential induction mechanism of cyclin D1 and D3. Molecular reproduction and development 19970401
Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors alpha and beta. Endocrinology 19970301
DDT mimicks estradiol stimulation of breast cancer cells to enter the cell cycle. Molecular carcinogenesis 19970201
Superinduction of c-fos gene expression by estrogen in cultured guinea-pig endometrial cells requires priming by a cycloheximide-dependent mechanism. Endocrinology 19920901
Placenta defects and embryonic lethality resulting from disruption of mouse hydroxysteroid (17-beta) dehydrogenase 2 gene. Molecular endocrinology (Baltimore, Md.)
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