1H-Isoindole-1,3(2H)-dione, 2-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]hexahydro-, hydrochloride (1:1), (3aR,7aS)-rel-
| Title | Journal |
|---|---|
| Why are most phospholipidosis inducers also hERG blockers? | Archives of toxicology 20171201 |
| Efficacy and tolerability of perospirone in schizophrenia: a systematic review and meta-analysis of randomized controlled trials. | CNS drugs 20130901 |
| State and trait markers of emotionally charged visual event-related potentials (P300) in drug-naïve schizophrenia. | Psychiatry and clinical neurosciences 20120601 |
| Improvement in QTc prolongation induced by zotepine following a switch to perospirone. | Psychiatry and clinical neurosciences 20120401 |
| Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2. | Journal of medicinal chemistry 20110714 |
| Pharmacokinetics and metabolism update for some recent antipsychotics. | Expert opinion on drug metabolism & toxicology 20110701 |
| Mirtazapine in combination with perospirone synergistically enhances dopamine release in the rat prefrontal cortex via 5-HT1A receptor activation. | Psychiatry and clinical neurosciences 20110401 |
| A case of schizophrenia with Meige syndrome induced by long-term aripiprazole successfully treated with perospirone. | Progress in neuro-psychopharmacology & biological psychiatry 20110115 |
| An unblinded comparison of the clinical and cognitive effects of switching from first-generation antipsychotics to aripiprazole, perospirone or olanzapine in patients with chronic schizophrenia. | Progress in neuro-psychopharmacology & biological psychiatry 20110115 |
| The wide variability of perospirone metabolism and the effect of perospirone on prolactin in psychiatric patients. | Progress in neuro-psychopharmacology & biological psychiatry 20100816 |
| Dopamine D2 receptor occupancy by perospirone: a positron emission tomography study in patients with schizophrenia and healthy subjects. | Psychopharmacology 20100501 |
| Prolactin fluctuation over the course of a day during treatments with three atypical antipsychotics in schizophrenic patients. | Human psychopharmacology 20100401 |
| Effect of perospirone on P300 electrophysiological activity and social cognition in schizophrenia: a three-dimensional analysis with sloreta. | Psychiatry research 20090630 |
| Randomized clinical comparison of perospirone and risperidone in patients with schizophrenia: Kansai Psychiatric Multicenter Study. | Psychiatry and clinical neurosciences 20090601 |
| Augmentation of antidepressants with perospirone for treatment-resistant major depressive disorder. | Progress in neuro-psychopharmacology & biological psychiatry 20090430 |
| Determination of azelnidipine by LC-ESI-MS and its application to a pharmacokinetic study in healthy Chinese volunteers. | Die Pharmazie 20080801 |
| Effect of the novel antipsychotic drug perospirone on P-glycoprotein function and expression in Caco-2 cells. | European journal of clinical pharmacology 20080701 |
| Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antipsychotic drug perospirone: role of serotonin 5-HT1A receptors. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080601 |
| [Usefulness of perospirone for the prevention of nausea related to opioid administration]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080401 |
| Long-term perospirone treatment with a single dose at bedtime in schizophrenia: relevant to intermittent dopamine D2 receptor antagonism. | Progress in neuro-psychopharmacology & biological psychiatry 20080215 |
| The effect of atypical antipsychotics, perospirone, ziprasidone and quetiapine on microglial activation induced by interferon-gamma. | Progress in neuro-psychopharmacology & biological psychiatry 20080101 |
| Effective adjunctive use of tandospirone with perospirone for enhancing verbal memory and quality of life in schizophrenia. | Progress in neuro-psychopharmacology & biological psychiatry 20070509 |
| Ultra-performance liquid chromatography-tandem mass spectrometry for the determination of atypical antipsychotics and some metabolites in in vitro samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501 |
| A pharmaco-EEG study on antipsychotic drugs in healthy volunteers. | Psychopharmacology 20070501 |
| Perospirone augmentation of paroxetine in treatment of refractory obsessive-compulsive disorder with depression. | Progress in neuro-psychopharmacology & biological psychiatry 20070330 |
| Determination of perospirone by liquid chromatography/electrospray mass spectrometry: application to a pharmacokinetic study in healthy Chinese volunteers. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301 |
| Alteration in serum neural cell adhesion molecule in patients of schizophrenia. | Human psychopharmacology 20070301 |
| Perospirone in the treatment of patients with delirium. | Psychiatry and clinical neurosciences 20070201 |
| Perospirone in treatment of Huntington's disease: a first case report. | Progress in neuro-psychopharmacology & biological psychiatry 20070130 |
| New-onset diabetic ketoacidosis induced by the addition of perospirone hydrochloride in a patient treated with risperidone. | Internal medicine (Tokyo, Japan) 20070101 |
| [Pharmacokinetics of perospirone hydrochloride at an excessive dose and changes in the serum prolactin level]. | Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20070101 |
| 5-HT1A receptor agonist properties of antipsychotics determined by [35S]GTPgammaS binding in rat hippocampal membranes. | Clinical and experimental pharmacology & physiology 20070101 |
| Neuroleptic malignant syndrome induced by perospirone. | The international journal of neuropsychopharmacology 20061001 |
| Perospirone is a new generation antipsychotic: evidence from a positron emission tomography study of serotonin 2 and D2 receptor occupancy in the living human brain. | Journal of clinical psychopharmacology 20061001 |
| Effect of carbamazepine on the single oral dose pharmacokinetics of perospirone and its active metabolite. | Progress in neuro-psychopharmacology & biological psychiatry 20060930 |
| The effect of perospirone on auditory P300 in schizophrenia: a preliminary study. | Progress in neuro-psychopharmacology & biological psychiatry 20060830 |
| Efficacy of perospirone in the management of aggressive behavior associated with dementia. | Progress in neuro-psychopharmacology & biological psychiatry 20060601 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Effective treatment of coprophagia in a patient with schizophrenia with the novel atypical antipsychotic drug perospirone. | Pharmacopsychiatry 20060501 |
| Perospirone in the treatment of schizophrenia: effect on verbal memory organization. | Progress in neuro-psychopharmacology & biological psychiatry 20060301 |
| Neuroleptic malignant syndrome related to a switch to perospirone and anticholinergic withdrawal. | The American journal of psychiatry 20060301 |
| Effects of itraconazole and tandospirone on the pharmacokinetics of perospirone. | Therapeutic drug monitoring 20060201 |
| Beneficial effects of perospirone on aggressive behavior associated with dementia. | Psychiatry and clinical neurosciences 20060201 |
| Perospirone for treatment of dissociative identity disorder. | Psychiatry and clinical neurosciences 20051001 |
| Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder. | Journal of pharmacological sciences 20051001 |
| Perospirone improves food refusal in elderly patients with mental disorders. | Journal of clinical psychopharmacology 20050601 |
| Influence of aging on the improvement of subjective sleep quality by atypical antipsychotic drugs in patients with schizophrenia: comparison of middle-aged and older adults. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20050501 |
| Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone. | Biopharmaceutics & drug disposition 20050301 |
| Efficacy of carbamazepine against neuroleptic-induced akathisia in treatment with perospirone: case series. | Progress in neuro-psychopharmacology & biological psychiatry 20050201 |
| Correlation between plasma homovanillic acid levels and the response to atypical antipsychotics in male patients with schizophrenia. | Clinical neuropharmacology 20050101 |
| A novel antipsychotic, perospirone, has antiserotonergic and antidopaminergic effects in human brain: findings from neuroendocrine challenge tests. | Psychopharmacology 20041101 |
| Effects of changing from typical to atypical antipsychotic drugs on subjective sleep quality in patients with schizophrenia in a Japanese population. | The Journal of clinical psychiatry 20041101 |
| Effects of serotonin-dopamine antagonists on prepulse inhibition and neurotransmitter contents in the rat cortex. | Neuroscience letters 20040812 |
| Steady-state pharmacokinetics of a new antipsychotic agent perospirone and its active metabolite, and its relationship with prolactin response. | Therapeutic drug monitoring 20040801 |
| Perospirone, a novel atypical antipsychotic drug, potentiates fluoxetine-induced increases in dopamine levels via multireceptor actions in the rat medial prefrontal cortex. | Neuroscience letters 20040624 |
| Two cases of perospirone-induced mania in schizophrenia. | The Journal of clinical psychiatry 20040101 |
| Use of perospirone for obesity and diabetes mellitus in patients with schizophrenia: three case reports. | International clinical psychopharmacology 20040101 |
| Impact of a switch from typical to atypical antipsychotic drugs on quality of life and gonadal hormones in male patients with schizophrenia. | Neuro endocrinology letters 20040101 |
| [Treatment of 'the premonitory state of schizophrenia' with atypical antipsychotics]. | Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20040101 |
| Perospirone, a novel antipsychotic agent, hyperpolarizes rat dorsal raphe neurons via 5-HT1A receptor. | Journal of pharmacological sciences 20030901 |
| Determination of a new atypical antipsychotic agent perospirone and its metabolite in human plasma by automated column-switching high-performance liquid chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030615 |
| Prolactin levels in schizophrenic patients receiving perospirone in comparison to risperidone. | Journal of pharmacological sciences 20030301 |
| [An introduction to antipsychotics]. | Ryoikibetsu shokogun shirizu 20030101 |
| [Extrapyramidal syndrome]. | Ryoikibetsu shokogun shirizu 20030101 |
| In vitro metabolism of perospirone in rat, monkey and human liver microsomes. | European journal of drug metabolism and pharmacokinetics 20030101 |
| In vitro drug-drug interactions with perospirone and concomitantly administered drugs in human liver microsomes. | European journal of drug metabolism and pharmacokinetics 20030101 |
| Distribution of perospirone to melanin in pigmented rats. | European journal of drug metabolism and pharmacokinetics 20030101 |
| [Perospirone therapy in elderly patients with schizophrenia]. | Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 20030101 |
| Perospirone (Sumitomo Pharmaceuticals). | Current opinion in investigational drugs (London, England : 2000) 20020101 |
| Perospirone. | CNS drugs 20010101 |
| Pharmacological actions of SM-9018, a new neuroleptic drug with both potent 5-hydroxytryptamine2 and dopamine2 antagonistic actions. | Japanese journal of pharmacology 19900701 |