Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-
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Ospemifene metabolism in humans in vitro and in vivo: metabolite identification, quantitation, and CYP assignment of major hydroxylations. | Drug metabolism and drug interactions 20130101 |
An update on selective estrogen receptor modulators for the prevention and treatment of osteoporosis. | Maturitas 20120301 |
Ospemifene and 4-hydroxyospemifene effectively prevent and treat breast cancer in the MTag.Tg transgenic mouse model. | Menopause (New York, N.Y.) 20120101 |
Liver X receptors as regulators of macrophage inflammatory and metabolic pathways. | Biochimica et biophysica acta 20110801 |
Pharmacologic evaluation of ospemifene. | Expert opinion on drug metabolism & toxicology 20100601 |
An innovative method to classify SERMs based on the dynamics of estrogen receptor transcriptional activity in living animals. | Molecular endocrinology (Baltimore, Md.) 20100401 |
Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-gamma-inducible protein-10 by astrocytes exposed to inflammatory challenge in vitro. | Glia 20100101 |
Ospemifene effectively treats vulvovaginal atrophy in postmenopausal women: results from a pivotal phase 3 study. | Menopause (New York, N.Y.) 20100101 |
Endometrial safety: a key hurdle for selective estrogen receptor modulators in development. | Menopause (New York, N.Y.) 20100101 |
Current and emerging pharmacologic therapies for the management of postmenopausal osteoporosis. | Journal of women's health (2002) 20091001 |
Ospemifene use in postmenopausal women. | Expert opinion on investigational drugs 20090601 |
Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells. | Molecular and cellular endocrinology 20080716 |
Pharmacologic effects of ospemifene in rhesus macaques: a pilot study. | Basic & clinical pharmacology & toxicology 20080601 |
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro. | British journal of pharmacology 20070601 |
The cardiovascular effects of selective estrogen receptor modulators. | Annals of the New York Academy of Sciences 20061201 |
Effects of ospemifene and raloxifene on biochemical markers of bone turnover in postmenopausal women. | Journal of bone and mineral metabolism 20060101 |
Ineffectiveness of American ginseng in the prevention of dimethylbenzanthracene-induced mammary tumors in mice. | Oncology research 20060101 |
Ospemifene inhibits the growth of dimethylbenzanthracene-induced mammary tumors in Sencar mice. | The Journal of steroid biochemistry and molecular biology 20051101 |
Effects of ospemifene and raloxifene on hormonal status, lipids, genital tract, and tolerability in postmenopausal women. | Menopause (New York, N.Y.) 20050301 |
Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ. | Breast cancer research : BCR 20050101 |
Selective estrogen receptor modulators prevent neointima formation after vascular injury. | Molecular and cellular endocrinology 20041130 |
Ospemifene Hormos. | Current opinion in investigational drugs (London, England : 2000) 20040401 |
Effects of ospemifene, a novel SERM, on biochemical markers of bone turnover in healthy postmenopausal women. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040301 |
Comparative study of the short-term effects of a novel selective estrogen receptor modulator, ospemifene, and raloxifene and tamoxifen on rat uterus. | The Journal of steroid biochemistry and molecular biology 20040201 |
Effects of ospemifene, a novel SERM, on hormones, genital tract, climacteric symptoms, and quality of life in postmenopausal women: a double-blind, randomized trial. | Menopause (New York, N.Y.) 20030101 |
Effects of ospemifene, a novel SERM, on vascular markers and function in healthy, postmenopausal women. | Menopause (New York, N.Y.) 20030101 |
Effects of ospemifene (FC-1271a) on uterine endometrium, vaginal maturation index, and hormonal status in healthy postmenopausal women. | Maturitas 20021120 |
In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer. | The Journal of steroid biochemistry and molecular biology 20010601 |
Cone voltage and collision cell collision-induced dissociation study of triphenylethylenes of pharmaceutical interest. | Rapid communications in mass spectrometry : RCM 20010101 |