Home Halogens Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-

Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-

CAS No.:
128607-22-7
Catalog Number:
AG000Y8C
Molecular Formula:
C24H23ClO2
Molecular Weight:
378.8912
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
99%
1 week
United States
$140
- +
50mg
≥98%
1 week
United States
$153
- +
100mg
99%
1 week
United States
$223
- +
200mg
99%
1 week
United States
$307
- +
500mg
≥98%
1 week
United States
$728
- +
Product Description
Catalog Number:
AG000Y8C
Chemical Name:
Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-buten-1-yl]phenoxy]-
CAS Number:
128607-22-7
Molecular Formula:
C24H23ClO2
Molecular Weight:
378.8912
MDL Number:
MFCD00871890
IUPAC Name:
2-[4-[(Z)-4-chloro-1,2-diphenylbut-1-enyl]phenoxy]ethanol
InChI:
InChI=1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-
InChI Key:
LUMKNAVTFCDUIE-VHXPQNKSSA-N
SMILES:
ClCC/C(=C(\c1ccccc1)/c1ccc(cc1)OCCO)/c1ccccc1
UNII:
B0P231ILBK
Properties
Complexity:
441  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
378.139g/mol
Formal Charge:
0
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
378.896g/mol
Monoisotopic Mass:
378.139g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
29.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
6.5  
Literature
Title Journal
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An update on selective estrogen receptor modulators for the prevention and treatment of osteoporosis. Maturitas 20120301
Ospemifene and 4-hydroxyospemifene effectively prevent and treat breast cancer in the MTag.Tg transgenic mouse model. Menopause (New York, N.Y.) 20120101
Liver X receptors as regulators of macrophage inflammatory and metabolic pathways. Biochimica et biophysica acta 20110801
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An innovative method to classify SERMs based on the dynamics of estrogen receptor transcriptional activity in living animals. Molecular endocrinology (Baltimore, Md.) 20100401
Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-gamma-inducible protein-10 by astrocytes exposed to inflammatory challenge in vitro. Glia 20100101
Ospemifene effectively treats vulvovaginal atrophy in postmenopausal women: results from a pivotal phase 3 study. Menopause (New York, N.Y.) 20100101
Endometrial safety: a key hurdle for selective estrogen receptor modulators in development. Menopause (New York, N.Y.) 20100101
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Ospemifene use in postmenopausal women. Expert opinion on investigational drugs 20090601
Estrogen and the selective estrogen receptor modulator (SERM) protection against cell death in estrogen receptor alpha and beta expressing U2OS cells. Molecular and cellular endocrinology 20080716
Pharmacologic effects of ospemifene in rhesus macaques: a pilot study. Basic & clinical pharmacology & toxicology 20080601
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Ineffectiveness of American ginseng in the prevention of dimethylbenzanthracene-induced mammary tumors in mice. Oncology research 20060101
Ospemifene inhibits the growth of dimethylbenzanthracene-induced mammary tumors in Sencar mice. The Journal of steroid biochemistry and molecular biology 20051101
Effects of ospemifene and raloxifene on hormonal status, lipids, genital tract, and tolerability in postmenopausal women. Menopause (New York, N.Y.) 20050301
Selective estrogen receptor modulators inhibit growth and progression of premalignant lesions in a mouse model of ductal carcinoma in situ. Breast cancer research : BCR 20050101
Selective estrogen receptor modulators prevent neointima formation after vascular injury. Molecular and cellular endocrinology 20041130
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Effects of ospemifene, a novel SERM, on biochemical markers of bone turnover in healthy postmenopausal women. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20040301
Comparative study of the short-term effects of a novel selective estrogen receptor modulator, ospemifene, and raloxifene and tamoxifen on rat uterus. The Journal of steroid biochemistry and molecular biology 20040201
Effects of ospemifene, a novel SERM, on hormones, genital tract, climacteric symptoms, and quality of life in postmenopausal women: a double-blind, randomized trial. Menopause (New York, N.Y.) 20030101
Effects of ospemifene, a novel SERM, on vascular markers and function in healthy, postmenopausal women. Menopause (New York, N.Y.) 20030101
Effects of ospemifene (FC-1271a) on uterine endometrium, vaginal maturation index, and hormonal status in healthy postmenopausal women. Maturitas 20021120
In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer. The Journal of steroid biochemistry and molecular biology 20010601
Cone voltage and collision cell collision-induced dissociation study of triphenylethylenes of pharmaceutical interest. Rapid communications in mass spectrometry : RCM 20010101
Properties