sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks HS-173

HS-173

CAS No.:
1276110-06-5
Catalog Number:
AG000X80
Molecular Formula:
C21H18N4O4S
Molecular Weight:
422.4570
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$97
- +
5mg
≥98%
1 week
United States
$178
- +
10mg
≥98%
1 week
United States
$279
- +
25mg
≥98%
1 week
United States
$510
- +
50mg
99%
1 week
United States
$807
- +
Product Description
Catalog Number:
AG000X80
Chemical Name:
HS-173
CAS Number:
1276110-06-5
Molecular Formula:
C21H18N4O4S
Molecular Weight:
422.4570
MDL Number:
MFCD28023584
IUPAC Name:
ethyl 6-[5-(benzenesulfonamido)pyridin-3-yl]imidazo[1,2-a]pyridine-3-carboxylate
InChI:
InChI=1S/C21H18N4O4S/c1-2-29-21(26)19-13-23-20-9-8-15(14-25(19)20)16-10-17(12-22-11-16)24-30(27,28)18-6-4-3-5-7-18/h3-14,24H,2H2,1H3
InChI Key:
SEKOTFCHZNXZMM-UHFFFAOYSA-N
SMILES:
CCOC(=O)c1cnc2n1cc(cc2)c1cncc(c1)NS(=O)(=O)c1ccccc1
Properties
Complexity:
692  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
422.105g/mol
Formal Charge:
0
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
422.459g/mol
Monoisotopic Mass:
422.105g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
111A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.4  
Literature
Title Journal
HS-173, a novel phosphatidylinositol 3-kinase (PI3K) inhibitor, has anti-tumor activity through promoting apoptosis and inhibiting angiogenesis. Cancer letters 20130101
HS-173, a novel PI3K inhibitor, attenuates the activation of hepatic stellate cells in liver fibrosis. Scientific reports 20130101
Design and synthesis of imidazopyridine analogues as inhibitors of phosphoinositide 3-kinase signaling and angiogenesis. Journal of medicinal chemistry 20110414
Properties