Home Carboxys 1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS No.:
127294-70-6
Catalog Number:
AG000WWF
Molecular Formula:
C20H24FN3O4
Molecular Weight:
389.4207
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$75
- +
5g
98%
In Stock USA
United States
$225
- +
Product Description
Catalog Number:
AG000WWF
Chemical Name:
1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
CAS Number:
127294-70-6
Molecular Formula:
C20H24FN3O4
Molecular Weight:
389.4207
MDL Number:
MFCD00864925
IUPAC Name:
1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(methylamino)piperidin-1-yl]-4-oxoquinoline-3-carboxylic acid
InChI:
InChI=1S/C20H24FN3O4/c1-22-11-4-3-7-23(9-11)17-15(21)8-13-16(19(17)28-2)24(12-5-6-12)10-14(18(13)25)20(26)27/h8,10-12,22H,3-7,9H2,1-2H3,(H,26,27)
InChI Key:
MGQLHRYJBWGORO-UHFFFAOYSA-N
SMILES:
CNC1CCCN(C1)c1c(F)cc2c(c1OC)n(cc(c2=O)C(=O)O)C1CC1
Properties
Complexity:
668  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
389.175g/mol
Formal Charge:
0
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
389.427g/mol
Monoisotopic Mass:
389.175g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
82.1A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6  
Literature
Title Journal
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In the quest of drugs for bad bugs: are newer fluoroquinolones any better? Journal of laboratory physicians 20110101
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Aquatic photochemistry of fluoroquinolone antibiotics: kinetics, pathways, and multivariate effects of main water constituents. Environmental science & technology 20100401
Gatifloxacin, moxifloxacin, and balofloxacin resistance due to mutations in the gyrA and parC genes of Staphylococcus epidermidis strains isolated from patients with endophthalmitis, corneal ulcers and conjunctivitis. Ophthalmic research 20090101
Ethyl 1-cyclo-propyl-6,7-difluoro-8-meth-oxy-4-oxo-1,4-dihydro-quinoline-3-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20081101
[Synthesis and antibacterial activity of 7-(3-amino-4-alkoxyimino-1 -piperidyl) -quinolones]. Yao xue xue bao = Acta pharmaceutica Sinica 20080801
[Determination of balofloxacin in human plasma by HPLC with solid-phase extraction]. Se pu = Chinese journal of chromatography 20071101
High performance liquid chromatography-electrospray ionization mass spectrometric determination of balofloxacin in human plasma and its pharmacokinetics. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501
[Studies on the reaction of balofloxacin with bovine serum albumin]. Guang pu xue yu guang pu fen xi = Guang pu 20060801
Electrophysiological safety of novel fluoroquinolone antibiotic agents gemifloxacin and balofloxacin. Drug and chemical toxicology 20060101
[Interaction between balofloxacin and DNA and the influence of Mg2+ on the interaction]. Yao xue xue bao = Acta pharmaceutica Sinica 20050701
Balofloxacin Choongwae. Current opinion in investigational drugs (London, England : 2000) 20030201
[In vitro antimycobacterial activities of a new quinolone, balofloxacin]. Kekkaku : [Tuberculosis] 20010101
History of quinolones and their side effects. Chemotherapy 20010101
[In vitro anti-MAC activities of new quinolones in focus (2)]. Kekkaku : [Tuberculosis] 19960901
[Determination of antimycobacterial activities of fluoroquinolones against clinical isolates of Mycobacterium tuberculosis: comparative determination with egg-based Ogawa and agar-based Middlebrook 7H10 media]. Kekkaku : [Tuberculosis] 19960801
Properties