Home Sulfos 5-Isoquinolinesulfonamide, N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]-

5-Isoquinolinesulfonamide, N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]-

CAS No.:
127243-85-0
Catalog Number:
AG000WT2
Molecular Formula:
C20H20BrN3O2S
Molecular Weight:
446.3607
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Purity
Availability
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Price(USD)
Quantity
  
Product Description
Catalog Number:
AG000WT2
Chemical Name:
5-Isoquinolinesulfonamide, N-[2-[[3-(4-bromophenyl)-2-propen-1-yl]amino]ethyl]-
CAS Number:
127243-85-0
Molecular Formula:
C20H20BrN3O2S
Molecular Weight:
446.3607
MDL Number:
MFCD00214119
IUPAC Name:
N-[2-[[(E)-3-(4-bromophenyl)prop-2-enyl]amino]ethyl]isoquinoline-5-sulfonamide
InChI:
InChI=1S/C20H20BrN3O2S/c21-18-8-6-16(7-9-18)3-2-11-22-13-14-24-27(25,26)20-5-1-4-17-15-23-12-10-19(17)20/h1-10,12,15,22,24H,11,13-14H2/b3-2+
InChI Key:
ZKZXNDJNWUTGDK-NSCUHMNNSA-N
SMILES:
Brc1ccc(cc1)C=CCNCCNS(=O)(=O)c1cccc2c1ccnc2
UNII:
M876330O56
Properties
Complexity:
570  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
445.046g/mol
Formal Charge:
0
Heavy Atom Count:
27  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
446.363g/mol
Monoisotopic Mass:
445.046g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
79.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3.5  
Literature
Title Journal
Protective mechanisms involving enhanced mitochondrial functions and mitophagy against T-2 toxin-induced toxicities in GH3 cells. Toxicology letters 20181001
Imidacloprid, a neonicotinoid insecticide, facilitates tyrosine hydroxylase transcription and phenylethanolamine N-methyltransferase mRNA expression to enhance catecholamine synthesis and its nicotine-evoked elevation in PC12D cells. Toxicology 20180201
Distinctive effects of licarin A on lipolysis mediated by PKA and on formation of brown adipocytes from C3H10T1/2 mesenchymal stem cells. Toxicology and applied pharmacology 20180201
PKA/CREB and NF-κB pathway regulates AKNA transcription: A novel insight into T-2 toxin-induced inflammation and GH deficiency in GH3 cells. Toxicology 20171201
Leptin induces CREB-dependent aromatase activation through COX-2 expression in breast cancer cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170801
UDCA and CDCA alleviate 17α-ethinylestradiol-induced cholestasis through PKA-AMPK pathways in rats. Toxicology and applied pharmacology 20161115
Convergent Signaling Pathways Regulate Parathyroid Hormone and Fibroblast Growth Factor-23 Action on NPT2A-mediated Phosphate Transport. The Journal of biological chemistry 20160902
Propofol reduced myocardial contraction of vertebrates partly by mediating the cyclic AMP-dependent protein kinase phosphorylation pathway. Toxicology 20160715
Niclosamide blocks glucagon phosphorylation of Ser552 on β-catenin in primary rat hepatocytes via PKA signalling. The Biochemical journal 20160501
Serotonergic regulation of melanocyte conversion: A bioelectrically regulated network for stochastic all-or-none hyperpigmentation. Science signaling 20151006
Coordinated induction of GST and MRP2 by cAMP in Caco-2 cells: Role of protein kinase A signaling pathway and toxicological relevance. Toxicology and applied pharmacology 20150901
Resveratrol improves hepatic steatosis by inducing autophagy through the cAMP signaling pathway. Molecular nutrition & food research 20150801
Effects of monocrotophos pesticide on steroidogenesis and transcription of steroidogenic enzymes in rainbow trout RTG-2 cells involving the protein kinase A signal pathway. Toxicology in vitro : an international journal published in association with BIBRA 20150201
The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling. Nature communications 20150101
Alteration in cellular viability, pro-inflammatory cytokines and nitric oxide production in nephrotoxicity generation by Amphotericin B: involvement of PKA pathway signaling. Journal of applied toxicology : JAT 20141201
Multiple treatments with L-3,4-dihydroxyphenylalanine modulate dopamine biosynthesis and neurotoxicity through the protein kinase A-transient extracellular signal-regulated kinase and exchange protein activation by cyclic AMP-sustained extracellular signal-regulated kinase signaling pathways. Journal of neuroscience research 20141201
Upregulation of CYP1B1 expression by inflammatory cytokines is mediated by the p38 MAP kinase signal transduction pathway. Carcinogenesis 20141101
Quercetin-3-O-glucuronide inhibits noradrenaline-promoted invasion of MDA-MB-231 human breast cancer cells by blocking β₂-adrenergic signaling. Archives of biochemistry and biophysics 20140901
Highly expressed protein kinase A inhibitor α and suppression of protein kinase A may potentiate acetaminophen-induced hepatotoxicity. Toxicology letters 20140817
Mechanism of raloxifene-induced upregulation of glutamate transporters in rat primary astrocytes. Glia 20140801
Expression and regulation of stromal cell-derived factor-1 (SDF1) and chemokine CXC motif receptor 4 (CXCR4) in equine and bovine preovulatory follicles. Molecular and cellular endocrinology 20140625
2-(4-Methoxyphenyl)ethyl-2-acetamido-2-deoxy-β-d-pyranoside confers neuroprotection in cell and animal models of ischemic stroke through calpain1/PKA/CREB-mediated induction of neuronal glucose transporter 3. Toxicology and applied pharmacology 20140615
Characterization of the regulatory mechanisms of activating transcription factor 3 by hypertrophic stimuli in rat cardiomyocytes. PloS one 20140101
Resveratrol attenuates vascular endothelial inflammation by inducing autophagy through the cAMP signaling pathway. Autophagy 20131201
Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells. Phytomedicine : international journal of phytotherapy and phytopharmacology 20130515
A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. The Biochemical journal 20130415
Mechanisms of action of hormone-sensitive lipase in mouse Leydig cells: its role in the regulation of the steroidogenic acute regulatory protein. The Journal of biological chemistry 20130322
Identification and characterization of small molecules as potent and specific EPAC2 antagonists. Journal of medicinal chemistry 20130214
A critical role for MAPK signalling pathways in the transcriptional regulation of toll like receptors. PloS one 20130101
Role of yessotoxin in calcium and cAMP-crosstalks in primary and K-562 human lymphocytes: the effect is mediated by anchor kinase A mitochondrial proteins. Journal of cellular biochemistry 20121201
TNF-α triggers rapid membrane insertion of Ca(2+) permeable AMPA receptors into adult motor neurons and enhances their susceptibility to slow excitotoxic injury. Experimental neurology 20121201
cAMP-dependent protein kinase is essential for hypoxia-mediated epithelial-mesenchymal transition, migration, and invasion in lung cancer cells. Cellular signalling 20121201
Role of mitochondrial activation in PACAP dependent neurite outgrowth. Journal of molecular neuroscience : MN 20121101
PYK-2 is tyrosine phosphorylated after activation of pituitary adenylate cyclase activating polypeptide receptors in lung cancer cells. Journal of molecular neuroscience : MN 20121101
Cilomilast enhances osteoblast differentiation of mesenchymal stem cells and bone formation induced by bone morphogenetic protein 2. Biochimie 20121101
β-Adrenergic receptor stimulation increases surface NKCC2 expression in rat thick ascending limbs in a process inhibited by phosphodiesterase 4. American journal of physiology. Renal physiology 20121101
Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes. Journal of lipid research 20121101
GLP-1 analog liraglutide protects against oxidative stress and albuminuria in streptozotocin-induced diabetic rats via protein kinase A-mediated inhibition of renal NAD(P)H oxidases. Metabolism: clinical and experimental 20121001
Arsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome. Cardiovascular research 20121001
H-89 decreases the gain of excitation-contraction coupling and attenuates calcium sparks in the absence of beta-adrenergic stimulation. European journal of pharmacology 20120915
Phosphodiesterase inhibitor modulation of brain microvascular endothelial cell barrier properties. Journal of the neurological sciences 20120915
Crosstalk between adenosine A1 and β1-adrenergic receptors regulates translocation of PKCε in isolated rat cardiomyocytes. Journal of cellular physiology 20120901
Insulin increases epiblast cell number of in vitro cultured mouse embryos via the PI3K/GSK3/p53 pathway. Stem cells and development 20120901
cAMP-elevation mediated by β-adrenergic stimulation inhibits salt-inducible kinase (SIK) 3 activity in adipocytes. Cellular signalling 20120901
Control of alternative splicing by forskolin through hnRNP K during neuronal differentiation. Nucleic acids research 20120901
GPR30 regulates glutamate transporter GLT-1 expression in rat primary astrocytes. The Journal of biological chemistry 20120803
Extracellular calcium-sensing receptor is critical in hypoxic pulmonary vasoconstriction. Antioxidants & redox signaling 20120801
Phthalates stimulate the epithelial to mesenchymal transition through an HDAC6-dependent mechanism in human breast epithelial stem cells. Toxicological sciences : an official journal of the Society of Toxicology 20120801
Regulation of glomerulotubular balance. I. Impact of dopamine on flow-dependent transport. American journal of physiology. Renal physiology 20120801
Acidosis-induced V-ATPase trafficking in salivary ducts is initiated by cAMP/PKA/CREB pathway via regulation of Rab11b expression. The international journal of biochemistry & cell biology 20120801
Estradiol acts directly and indirectly on multiple signaling pathways to phosphorylate cAMP-response element binding protein in GnRH neurons. Endocrinology 20120801
Anomalous dispersion analysis of inhibitor flexibility: a case study of the kinase inhibitor H-89. Acta crystallographica. Section F, Structural biology and crystallization communications 20120801
Modafinil inhibits K(Ca)3.1 currents and muscle contraction via a cAMP-dependent mechanism. Pharmacological research 20120701
Sar1 translocation onto the ER-membrane for vesicle budding has different pathways for promotion and suppression of ER-to-Golgi transport mediated through H89-sensitive kinase and ER-resident G protein. Molecular and cellular biochemistry 20120701
Astaxanthin attenuates the UVB-induced secretion of prostaglandin E2 and interleukin-8 in human keratinocytes by interrupting MSK1 phosphorylation in a ROS depletion-independent manner. Experimental dermatology 20120701
Endothelial cells are able to synthesize and release catecholamines both in vitro and in vivo. Hypertension (Dallas, Tex. : 1979) 20120701
5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP. Bioorganic & medicinal chemistry letters 20120615
Prostanoid EP₁ receptors mediate up-regulation of the orphan nuclear receptor Nurr1 by cAMP-independent activation of protein kinase A, CREB and NF-κB. British journal of pharmacology 20120601
Activation of cyclic adenosine monophosphate-dependent protein kinase a signaling prevents liver ischemia/reperfusion injury in mice. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120601
Alternariol induces DNA polymerase β expression through the PKA-CREB signaling pathway. International journal of oncology 20120601
The role of microRNA-23b in the differentiation of MSC into chondrocyte by targeting protein kinase A signaling. Biomaterials 20120601
Mechanism of β-catenin-mediated transcriptional regulation of epidermal growth factor receptor expression in glycogen synthase kinase 3 β-inactivated prostate cancer cells. The Journal of biological chemistry 20120525
Conjugates of 5-isoquinolinesulfonylamides and oligo-D-arginine possess high affinity and selectivity towards Rho kinase (ROCK). Bioorganic & medicinal chemistry letters 20120515
Downregulation of phosphodiesterase 4B (PDE4B) activates protein kinase A and contributes to the progression of prostate cancer. The Prostate 20120515
Molecular mechanisms of early growth response protein-1 (EGR-1) expression by quercetin in INS-1 beta-cells. Journal of cellular biochemistry 20120501
Protein kinase A signals apoptotic activation in glucose-deprived hepatocytes: participation of reactive oxygen species. Apoptosis : an international journal on programmed cell death 20120501
Prostaglandin E2 blocks menadione-induced apoptosis through the Ras/Raf/Erk signaling pathway in promonocytic leukemia cell lines. Molecules and cells 20120430
YC-1 potentiates cAMP-induced CREB activation and nitric oxide production in alveolar macrophages. Toxicology and applied pharmacology 20120415
Tumor necrosis factor activation of vagal afferent terminal calcium is blocked by cannabinoids. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120411
Collecting duct cells that lack normal cilia have mislocalized vasopressin-2 receptors. American journal of physiology. Renal physiology 20120401
PP2A inactivation is a crucial step in triggering apoptin-induced tumor-selective cell killing. Cell death & disease 20120401
Interactive effects of a protein kinase AII inhibitor and testosterone on spatial learning in the Morris water maze. Behavioural brain research 20120317
Dual contradictory roles of cAMP signaling pathways in hydroxyl radical production in the rat striatum. Free radical biology & medicine 20120315
Morphine decreases bacterial phagocytosis by inhibiting actin polymerization through cAMP-, Rac-1-, and p38 MAPK-dependent mechanisms. The American journal of pathology 20120301
Ca²⁺ signals of astrocytes are modulated by the NAD⁺/NADH redox state. Journal of neurochemistry 20120301
Phosphodiesterase inhibitors control A172 human glioblastoma cell death through cAMP-mediated activation of protein kinase A and Epac1/Rap1 pathways. Life sciences 20120227
Cell contact-dependent functional selectivity of β2-adrenergic receptor ligands in stimulating cAMP accumulation and extracellular signal-regulated kinase phosphorylation. The Journal of biological chemistry 20120224
Transient Ca2+ mobilization caused by osmotic shock initiates salmonid fish sperm motility. The Journal of experimental biology 20120215
Activation of corticotropin releasing factor receptor type 2 in the heart by corticotropin releasing factor offers cytoprotection against ischemic injury via PKA and PKC dependent signaling. Regulatory peptides 20120210
Identification of novel competing β2AR phospho-extracellular signal regulated kinase 1/2 signaling pathways in human trabecular meshwork cells. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20120201
Flavonoids exhibit diverse effects on CYP11B1 expression and cortisol synthesis. Toxicology and applied pharmacology 20120201
Role of stored calcium in the regulation of neurotransmitter quantum size. Bulletin of experimental biology and medicine 20120201
The afterhyperpolarizing potential following a train of action potentials is suppressed in an acute epilepsy model in the rat Cornu Ammonis 1 area. Neuroscience 20120110
Novel evidence that testosterone promotes cell proliferation and differentiation via G protein-coupled receptors in the rat L6 skeletal muscle myoblast cell line. Journal of cellular physiology 20120101
Inhibition of PKA attenuates memory deficits induced by β-amyloid (1-42), and decreases oxidative stress and NF-κB transcription factors. Behavioural brain research 20120101
Characterization of the cellular action of the MSK inhibitor SB-747651A. The Biochemical journal 20120101
Regulation of asymmetrical cytokinesis by cAMP during meiosis I in mouse oocytes. PloS one 20120101
Anti-inflammatory role of the cAMP effectors Epac and PKA: implications in chronic obstructive pulmonary disease. PloS one 20120101
Quercetin induces rapid eNOS phosphorylation and vasodilation by an Akt-independent and PKA-dependent mechanism. Pharmacology 20120101
Spatial expression of aquaporin 5 in mammalian cornea and lens, and regulation of its localization by phosphokinase A. Molecular vision 20120101
cAMP induces adhesion of microvascular smooth muscle cells to fibronectin via an Epac-mediated but PKA-independent mechanism. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101
β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A. PloS one 20120101
Resveratrol prevents ammonia toxicity in astroglial cells. PloS one 20120101
SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons. Toxicological sciences : an official journal of the Society of Toxicology 20111201
Differential involvement of protein kinase C and protein kinase A in ghrelin-induced growth hormone and gonadotrophin release from goldfish (Carassius auratus) pituitary cells. Journal of neuroendocrinology 20111201
Modulation of estrogen synthesis through activation of protein kinase A in H295R cells by extracts of estuary sediments. Environmental toxicology and chemistry 20111201
Effects of pentoxifylline and H-89 on epileptogenic activity of bucladesine in pentylenetetrazol-treated mice. European journal of pharmacology 20111130
Apolipoprotein A-I stimulates cholesteryl ester transfer protein and apolipoprotein E secretion from lipid-loaded macrophages; the role of NF-κB and PKA signaling pathways. Biochemical and biophysical research communications 20111125
Diethylstilbestrol enhances melanogenesis via cAMP-PKA-mediating up-regulation of tyrosinase and MITF in mouse B16 melanoma cells. Steroids 20111101
Aldosterone stimulates vacuolar H(+)-ATPase activity in renal acid-secretory intercalated cells mainly via a protein kinase C-dependent pathway. American journal of physiology. Cell physiology 20111101
Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway. Genes to cells : devoted to molecular & cellular mechanisms 20111101
Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. Nature biotechnology 20111101
Toll-like receptor 4-mediated cAMP production up-regulates B-cell activating factor expression in Raw264.7 macrophages. Experimental cell research 20111015
Effects of age on parathyroid hormone signaling in human marrow stromal cells. Aging cell 20111001
Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators. American journal of physiology. Lung cellular and molecular physiology 20111001
Immunomodulatory role of substance P in the wall lizard Hemidactylus flaviviridis: an in vitro study. Neuropeptides 20111001
Role of cAMP-PKA/CREB pathway in regulation of AQP 5 production in rat nasal epithelium. Rhinology 20111001
α1-adrenoceptor activation induces phosphorylation of β2-adrenoceptors in human prostate tissue. BJU international 20110901
ER-resident Gi2 protein controls sar1 translocation onto the ER during budding of transport vesicles. Journal of cellular biochemistry 20110901
Novel phosphorylation of aquaporin-5 at its threonine 259 through cAMP signaling in salivary gland cells. American journal of physiology. Cell physiology 20110901
cAMP-dependent protein kinase A activity modulates topiramate potentiation of GABA(A) receptors. Epilepsy research 20110901
Progesterone synthesis by human placental mitochondria is sensitive to PKA inhibition by H89. The international journal of biochemistry & cell biology 20110901
Expression of proliferin-related protein in testis and the biological significance in testosterone production. Molecular and cellular endocrinology 20110822
Idebenone inhibition of glutamate release from rat cerebral cortex nerve endings by suppression of voltage-dependent calcium influx and protein kinase A. Naunyn-Schmiedeberg's archives of pharmacology 20110701
Transcriptional regulation of the chemokine co-receptor CCR5 by the cAMP/PKA/CREB pathway. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110701
Coronary response to diadenosine tetraphosphate after ischemia-reperfusion in the isolated rat heart. European journal of pharmacology 20110625
2-(2-Fluorobenzamido)benzoate ethyl ester (EFB-1) inhibits superoxide production by human neutrophils and attenuates hemorrhagic shock-induced organ dysfunction in rats. Free radical biology & medicine 20110615
Thyroid hormones modulate GABA(A) receptor-mediated currents in hippocampal neurons. Neuropharmacology 20110601
Involvement of histaminergic receptor mechanisms in the stimulation of NT-3 synthesis in astrocytes. Neuropharmacology 20110601
A novel role for AMP-kinase in the regulation of the Na+/I--symporter and iodide uptake in the rat thyroid gland. American journal of physiology. Cell physiology 20110601
The relationship between pulsatile GnRH secretion and cAMP production in immortalized GnRH neurons. American journal of physiology. Endocrinology and metabolism 20110601
Neuropeptide Y, an orexigenic hormone, regulates phagocytic activity of lizard splenic phagocytes. Peptides 20110601
Design and evaluation of 3-aminopyrazolopyridinone kinase inhibitors inspired by the natural product indirubin. Bioorganic & medicinal chemistry 20110601
NMDA preconditioning protects against quinolinic acid-induced seizures via PKA, PI3K and MAPK/ERK signaling pathways. Behavioural brain research 20110516
GABAergic disinhibition induced pain hypersensitivity by upregulating NMDA receptor functions in spinal dorsal horn. Neuropharmacology 20110501
The heart: a novel gonadotrophin-releasing hormone target. Journal of neuroendocrinology 20110501
β-Endorphin inhibits phagocytic activity of lizard splenic phagocytes through μ receptor-coupled adenylate cyclase-protein kinase A signaling pathway. General and comparative endocrinology 20110501
5,7-dimethoxyflavone induces melanogenesis in B16F10 melanoma cells through cAMP-dependent signalling. Experimental dermatology 20110501
Melittin activates TRPV1 receptors in primary nociceptive sensory neurons via the phospholipase A2 cascade pathways. Biochemical and biophysical research communications 20110429
Adrenocorticotropin hormone (ACTH) effects on MAPK phosphorylation in human fasciculata cells and in embryonic kidney 293 cells expressing human melanocortin 2 receptor (MC2R) and MC2R accessory protein (MRAP)β. Molecular and cellular endocrinology 20110410
β2-adrenergic receptors inhibit the expression of collagen type II in growth plate chondrocytes by stimulating the AP-1 factor Jun-B. American journal of physiology. Endocrinology and metabolism 20110401
Heterotrimeric stimulatory GTP-binding proteins inhibit cisplatin-induced apoptosis by increasing X-linked inhibitor of apoptosis protein expression in cervical cancer cells. Cancer science 20110401
Stimulation of tube formation mediated through the prostaglandin EP2 receptor in rat luteal endothelial cells. The Journal of endocrinology 20110401
The gsp oncogene disrupts Ras/ERK-dependent prolactin gene regulation in gsp inducible somatotroph cell line. Endocrinology 20110401
Caffeine inhibits cell proliferation and regulates PKA/GSK3β pathways in U87MG human glioma cells. Molecules and cells 20110331
H89 sensitive kinase regulates the translocation of Sar1 onto the ER membrane through phosphorylation of ER-coupled β-tubulin. The international journal of biochemistry & cell biology 20110301
Nicotinic stimulation of catecholamine synthesis and tyrosine hydroxylase phosphorylation in cervine adrenal medullary chromaffin cells. Journal of neuroendocrinology 20110301
Luteinizing hormone (LH) acts through PKA and PKC to modulate T-type calcium currents and intracellular calcium transients in mice Leydig cells. Cell calcium 20110301
Protein kinase A-alpha directly phosphorylates FoxO1 in vascular endothelial cells to regulate expression of vascular cellular adhesion molecule-1 mRNA. The Journal of biological chemistry 20110225
Soluble adenylyl cyclase mediates bicarbonate-dependent corneal endothelial cell protection. American journal of physiology. Cell physiology 20110201
Luteinizing hormone receptor mRNA down-regulation is mediated through ERK-dependent induction of RNA binding protein. Molecular endocrinology (Baltimore, Md.) 20110201
Protein kinase C modulates NMDA receptors in the myenteric plexus of the guinea pig ileum during in vitro ischemia and reperfusion. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110201
Regulation of Sertoli-germ cell adhesion and sperm release by FSH and nonclassical testosterone signaling. Molecular endocrinology (Baltimore, Md.) 20110201
Interleukin-6 enhances glucose-stimulated insulin secretion from pancreatic beta-cells: potential involvement of the PLC-IP3-dependent pathway. Diabetes 20110201
Reactive oxygen species are indispensable in ovulation. Proceedings of the National Academy of Sciences of the United States of America 20110125
Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway. The Journal of biological chemistry 20110121
Role of MSK1 in the malignant phenotype of Ras-transformed mouse fibroblasts. The Journal of biological chemistry 20110107
Stimulation of β₂-adrenergic receptors inhibits calcineurin activity in CD4(+) T cells via PKA-AKAP interaction. Brain, behavior, and immunity 20110101
Ca efflux via the sarcolemmal Ca ATPase occurs only in the t-tubules of rat ventricular myocytes. Journal of molecular and cellular cardiology 20110101
Overexpression of CYP3A4, but not of CYP2D6, promotes hypoxic response and cell growth of Hep3B cells. Drug metabolism and pharmacokinetics 20110101
Regulation of aromatase expression by 1α,25(OH)2 vitamin D3 in rat testicular cells. Reproduction, fertility, and development 20110101
cAMP response element-binding protein (CREB) is required for epidermal growth factor (EGF)-induced cell proliferation and serum response element activation in neural stem cells isolated from the forebrain subventricular zone of adult mice. Endocrine journal 20110101
Signaling pathways in ascidian oocyte maturation: the roles of cAMP/Epac, intracellular calcium levels, and calmodulin kinase in regulating GVBD. Molecular reproduction and development 20110101
Identification of Toxoplasma gondii cAMP dependent protein kinase and its role in the tachyzoite growth. PloS one 20110101
Differential regulation of low and high voltage-activated calcium channels in neonatal rat myocytes following chronic PKA modulation. Channels (Austin, Tex.) 20110101
Differential effects of PKA-controlled CaMKK2 variants on neuronal differentiation. RNA biology 20110101
Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. PloS one 20110101
Ursodeoxycholic acid is conjugated with taurine to promote secretin-stimulated biliary hydrocholeresis in the normal rat. PloS one 20110101
Identification of the Raf-1 signaling pathway used by cAMP to inhibit p42/p44 MAPK in rat lacrimal gland acini: role in potentiation of protein secretion. Investigative ophthalmology & visual science 20101201
Mechanism of hCG-induced spermiation in the toad Rhinella arenarum (Amphibia, Anura). General and comparative endocrinology 20101201
Homotypic gap junctional communication associated with metastasis suppression increases with PKA activity and is unaffected by PI3K inhibition. Cancer research 20101201
Follicle-stimulating hormone promotes proliferation of cultured chicken ovarian germ cells through protein kinases A and C activation. Journal of Zhejiang University. Science. B 20101201
Calcitonin gene-related peptide (CGRP) inhibits apoptosis in human osteoblasts by β-catenin stabilization. Journal of cellular physiology 20101101
Upregulation of peripubertal rat Leydig cell steroidogenesis following 24 h in vitro and in vivo exposure to atrazine. Toxicological sciences : an official journal of the Society of Toxicology 20101101
Progesterone increases manganese superoxide dismutase expression via a cAMP-dependent signaling mediated by noncanonical Wnt5a pathway in human endometrial stromal cells. The Journal of clinical endocrinology and metabolism 20101101
Vasoactive intestinal polypeptide relaxes isolated rat pulmonary artery rings through two distinct mechanisms. The journal of physiological sciences : JPS 20101101
The choriocarcinoma cell line BeWo: syncytial fusion and expression of syncytium-specific proteins. Reproduction (Cambridge, England) 20101101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Inhibition of the mammalian target of rapamycin promotes cyclic AMP-induced differentiation of NG108-15 cells. Autophagy 20101101
The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells. Toxicology letters 20101020
Surprising similarity between mechanisms mediating low (1 Hz)-and high (100 Hz)-induced long-lasting synaptic potentiation in CA1 of the intact hippocampus. Neuroscience 20101013
Acute stimulation of white adipocyte respiration by PKA-induced lipolysis. Diabetes 20101001
Tongxinluo reduces myocardial no-reflow and ischemia-reperfusion injury by stimulating the phosphorylation of eNOS via the PKA pathway. American journal of physiology. Heart and circulatory physiology 20101001
The potential use of protein kinase D inhibitors for prevention/treatment of epidermal tumors. Journal of dermatological science 20101001
Quercetin potentiates insulin secretion and protects INS-1 pancreatic β-cells against oxidative damage via the ERK1/2 pathway. British journal of pharmacology 20101001
Identification of a site in Sar1 involved in the interaction with the cytoplasmic tail of glycolipid glycosyltransferases. The Journal of biological chemistry 20100924
Regulation of neuropathy target esterase by the cAMP/protein kinase A signal. Pharmacological research 20100901
Ginsenoside Rb1 promotes PC12 cell cycle kinetics through an adenylate cyclase-dependent protein kinase A pathway. Nutrition research (New York, N.Y.) 20100901
Protein kinase A and C signaling induces bilirubin potentiation of GABA/glycinergic synaptic transmission in rat ventral cochlear nucleus neurons. Brain research 20100812
Inhibition of long-term potentiation by valproic acid through modulation of cyclic AMP. Epilepsia 20100801
Cyclic AMP suppresses matrix metalloproteinase-1 expression through inhibition of MAPK and GSK-3beta. The Journal of investigative dermatology 20100801
Visualization of the interaction between Gbetagamma and tubulin during light-induced cell elongation of Blepharisma japonicum. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20100801
Cell specific dopamine modulation of the transient potassium current in the pyloric network by the canonical D1 receptor signal transduction cascade. Journal of neurophysiology 20100801
Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo. Circulation research 20100723
Melatonin potentiates glycine currents through a PLC/PKC signalling pathway in rat retinal ganglion cells. The Journal of physiology 20100715
Developmental regulation of protein kinase A expression and activity in Schistosoma mansoni. International journal for parasitology 20100701
Localised Ca channel phosphorylation modulates the distribution of L-type Ca current in cardiac myocytes. Journal of molecular and cellular cardiology 20100701
Spontaneous Ca waves in ventricular myocytes from failing hearts depend on Ca(2+)-calmodulin-dependent protein kinase II. Journal of molecular and cellular cardiology 20100701
Genetic deletion of COX-2 diminishes VEGF production in mouse retinal Müller cells. Experimental eye research 20100701
Adrenomedullin regulates sperm motility and oviductal ciliary beat via cyclic adenosine 5'-monophosphate/protein kinase A and nitric oxide. Endocrinology 20100701
Selective modulation of follicle-stimulating hormone signaling pathways with enhancing equine chorionic gonadotropin/antibody immune complexes. Endocrinology 20100601
Adenosine triphosphate stimulates RANKL expression through P2Y1 receptor-cyclo-oxygenase-dependent pathway in human periodontal ligament cells. Journal of periodontal research 20100601
Dipyridamole suppresses high glucose-induced osteopontin secretion and mRNA expression in rat aortic smooth muscle cells. Circulation journal : official journal of the Japanese Circulation Society 20100601
The endogenous cannabinoid anandamide inhibits transient receptor potential vanilloid type 1 receptor-mediated currents in rat cultured primary sensory neurons. Acta physiologica Hungarica 20100601
Dopaminergic modulation of endocannabinoid-mediated plasticity at GABAergic synapses in the prefrontal cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100526
IP3 receptor sensitization during in vivo amphetamine experience enhances NMDA receptor plasticity in dopamine neurons of the ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience 20100512
Inhibition of ATP-induced Ca2+ influx by corticosterone in dorsal root ganglion neurons. Neurochemical research 20100501
Exendin-4 prevents c-Jun N-terminal protein kinase activation by tumor necrosis factor-alpha (TNFalpha) and inhibits TNFalpha-induced apoptosis in insulin-secreting cells. Endocrinology 20100501
Studies in zebrafish reveal unusual cellular expression patterns of gonadotropin receptor messenger ribonucleic acids in the testis and unexpected functional differentiation of the gonadotropins. Endocrinology 20100501
Synergistic effect of vasoactive intestinal peptides on TNF-alpha-induced IL-6 synthesis in osteoblasts: amplification of p44/p42 MAP kinase activation. International journal of molecular medicine 20100501
Phosphatidylinositol- and phosphatidylcholine-transfer activity of PITPbeta is essential for COPI-mediated retrograde transport from the Golgi to the endoplasmic reticulum. Journal of cell science 20100415
Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERalpha pathway in human breast cancer cells. Toxicological sciences : an official journal of the Society of Toxicology 20100401
Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study. Naunyn-Schmiedeberg's archives of pharmacology 20100401
CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP. Genes & development 20100401
Bisphenol A-induced aromatase activation is mediated by cyclooxygenase-2 up-regulation in rat testicular Leydig cells. Toxicology letters 20100315
Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt). Journal of medicinal chemistry 20100311
The ceramide-1-phosphate analogue PCERA-1 modulates tumour necrosis factor-alpha and interleukin-10 production in macrophages via the cAMP-PKA-CREB pathway in a GTP-dependent manner. Immunology 20100301
Human papillomavirus type 16 E5 protein inhibits hydrogen-peroxide-induced apoptosis by stimulating ubiquitin-proteasome-mediated degradation of Bax in human cervical cancer cells. Carcinogenesis 20100301
CASK phosphorylation by PKA regulates the protein-protein interactions of CASK and expression of the NMDAR2b gene. Journal of neurochemistry 20100301
D-4F, an apolipoprotein A-I mimetic peptide, promotes cholesterol efflux from macrophages via ATP-binding cassette transporter A1. The Tohoku journal of experimental medicine 20100301
Enhanced antiproliferative and proapoptotic effects on prostate cancer cells by simultaneously inhibiting androgen receptor and cAMP-dependent protein kinase A. International journal of cancer 20100201
Involvement of the dehydroleucodine alpha-methylene-gamma-lactone function in GVBD inhibition in Bufo arenarum oocytes. Zygote (Cambridge, England) 20100201
Caffeine induces ram sperm hyperactivation independent of cAMP-dependent protein kinase. International journal of andrology 20100201
Regulatory role of monoamine neurotransmitters in astrocytic NT-3 synthesis. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20100201
The effect of midazolam on mouse Leydig cell steroidogenesis and apoptosis. Toxicology letters 20100201
Hatching and distribution of actin filaments in mouse blastocysts whose activities of protein kinase A were suppressed by H-89. The Journal of reproduction and development 20100201
Protein kinases A and C regulate receptor-mediated increases in cAMP in rabbit erythrocytes. American journal of physiology. Heart and circulatory physiology 20100201
Dipyridamole increases gap junction coupling in bovine GM-7373 aortic endothelial cells by a cAMP-protein kinase A dependent pathway. Journal of bioenergetics and biomembranes 20100201
Blocking L-type calcium channels reduced the threshold of cAMP-induced steroidogenic acute regulatory gene expression in MA-10 mouse Leydig cells. The Journal of endocrinology 20100101
Absence of ligand-independent transcriptional activation of the estrogen receptor via the estrogen response element in pituitary lactotrophs in primary culture. The Journal of steroid biochemistry and molecular biology 20100101
Podophyllotoxin induces CREB phosphorylation and CRE-driven gene expression via PKA but not MAPKs. Molecules and cells 20100101
Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner. PloS one 20100101
Aromatase gene expression in immature rat Sertoli cells: age-related changes in the FSH signalling pathway. Reproduction, fertility, and development 20100101
Pituitary adenylyl cyclase activating polypeptide inhibits gli1 gene expression and proliferation in primary medulloblastoma derived tumorsphere cultures. BMC cancer 20100101
Modulation of natural killer cell function by alpha-adrenoreceptor-coupled signalling. Neuro endocrinology letters 20100101
Quantitative analysis of lipid droplet fusion: inefficient steady state fusion but rapid stimulation by chemical fusogens. PloS one 20100101
Exendin-4, a GLP-1 receptor agonist, directly induces adiponectin expression through protein kinase A pathway and prevents inflammatory adipokine expression. Biochemical and biophysical research communications 20091218
H89, an inhibitor of PKA and MSK, inhibits cyclic-AMP response element binding protein-mediated MAPK phosphatase-1 induction by lipopolysaccharide. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20091201
Regulation of Na+/H+ exchanger NHE3 by glucagon-like peptide 1 receptor agonist exendin-4 in renal proximal tubule cells. American journal of physiology. Renal physiology 20091201
Nitric oxide and cyclic nucleotide signal transduction modulates synaptic vesicle turnover in human model neurons. Journal of neurochemistry 20091201
Protease-activated receptor 2-mediated protection of myocardial ischemia-reperfusion injury: role of transient receptor potential vanilloid receptors. American journal of physiology. Regulatory, integrative and comparative physiology 20091201
Ablation of transient receptor potential vanilloid 1 abolishes endothelin-induced increases in afferent renal nerve activity: mechanisms and functional significance. Hypertension (Dallas, Tex. : 1979) 20091201
Role of human chorionic gonadotropin in maintaining 11beta-hydroxysteroid dehydrogenase type 2 expression in human placental syncytiotrophoblasts. Placenta 20091201
Hyperhomocysteinemia stimulates hepatic glucose output and PEPCK expression. Acta biochimica et biophysica Sinica 20091201
Growth hormone-releasing peptide-2 stimulates secretion and synthesis of adrenocorticotropic hormone in mouse pituitary. Regulatory peptides 20091127
Docosahexaenoic acid enhances hepatic serum amyloid A expression via protein kinase A-dependent mechanism. The Journal of biological chemistry 20091120
Protein kinase A-dependent suppression of reactive oxygen species in transient focal ischemia in adrenomedullin-deficient mice. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20091101
Prostaglandin E2 inhibits advanced glycation end product-induced adhesion molecule expression, cytokine production, and lymphocyte proliferation in human peripheral blood mononuclear cells. The Journal of pharmacology and experimental therapeutics 20091101
Plasma protein kinase C (PKC)alpha as a biomarker for the diagnosis of cancers. Carcinogenesis 20091101
Pharmacological effects of carvedilol on T-type calcium current in murine HL-1 cells. European journal of pharmacology 20091025
Prostaglandin E2-induced masculinization of brain and behavior requires protein kinase A, AMPA/kainate, and metabotropic glutamate receptor signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience 20091021
Activation of adenylate cyclase by forskolin increases the protein stability of RCAN1 (DSCR1 or Adapt78). FEBS letters 20091006
Increased mitogen-activated protein kinase kinase/extracellularly regulated kinase activity in human endometrial stromal fibroblasts of women with endometriosis reduces 3',5'-cyclic adenosine 5'-monophosphate inhibition of cyclin D1. Endocrinology 20091001
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
Nuclear NF-kappaB p65 phosphorylation at serine 276 by protein kinase A contributes to the malignant phenotype of head and neck cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20091001
cAMP stimulates apical exocytosis of the renal Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in the thick ascending limb: role of protein kinase A. The Journal of biological chemistry 20090911
Establishment of screening system toward discovery of kinase inhibitors using label-free on-chip phosphorylation assays. Bio Systems 20090901
Glucagon-like peptide-1 protects mesenteric endothelium from injury during inflammation. Peptides 20090901
Histamine inhibits advanced glycation end products-induced adhesion molecule expression on human monocytes. The Journal of pharmacology and experimental therapeutics 20090901
Role PKA and p38 MAPK on ROS production in neutrophil age-related: Lack of IL-10 effect in older subjects. Mechanisms of ageing and development 20090901
Epac regulates UT-A1 to increase urea transport in inner medullary collecting ducts. Journal of the American Society of Nephrology : JASN 20090901
Milrinone inhibits hypoxia or hydrogen dioxide-induced persistent sodium current in ventricular myocytes. European journal of pharmacology 20090815
Dimethylfumarate inhibits NF-{kappa}B function at multiple levels to limit airway smooth muscle cell cytokine secretion. American journal of physiology. Lung cellular and molecular physiology 20090801
Effects of the cAMP-elevating agents cilostamide, cilostazol and forskolin on the phosphorylation of Akt and GSK-3beta in platelets. Thrombosis and haemostasis 20090801
PKA-mediated stabilization of FoxH1 negatively regulates ERalpha activity. Molecules and cells 20090731
{alpha}MSH and Cyclic AMP elevating agents control melanosome pH through a protein kinase A-independent mechanism. The Journal of biological chemistry 20090710
Delineation of the chemomechanosensory regulation of gastrin secretion using pure rodent G cells. Gastroenterology 20090701
Mechanisms of protein kinase C signaling in the modulation of 3',5'-cyclic adenosine monophosphate-mediated steroidogenesis in mouse gonadal cells. Endocrinology 20090701
Peripheral inflammation increased the synaptic expression of NMDA receptors in spinal dorsal horn. Pain 20090701
Relaxin alters cardiac myofilament function through a PKC-dependent pathway. American journal of physiology. Heart and circulatory physiology 20090701
Pituitary adenylate cyclase-activating polypeptide induces somatolactin release from cultured goldfish pituitary cells. Peptides 20090701
Low doses of bisphenol A promote human seminoma cell proliferation by activating PKA and PKG via a membrane G-protein-coupled estrogen receptor. Environmental health perspectives 20090701
Simvastatin suppresses leptin expression in 3T3-L1 adipocytes via activation of the cyclic AMP-PKA pathway induced by inhibition of protein prenylation. Journal of biochemistry 20090601
cAMP enhances estrogen-related receptor alpha (ERRalpha) transcriptional activity at the SP-A promoter by increasing its interaction with protein kinase A and steroid receptor coactivator 2 (SRC-2). Molecular endocrinology (Baltimore, Md.) 20090601
Regulated renin release from 3T3-L1 adipocytes. American journal of physiology. Endocrinology and metabolism 20090601
Bradykinin inhibits the transient outward K+ current in mouse Schwann cells via the cAMP/PKA pathway. American journal of physiology. Cell physiology 20090601
The role of the PDE4D cAMP phosphodiesterase in the regulation of glucagon-like peptide-1 release. British journal of pharmacology 20090601
Phosphorylation of myristoylated alanine-rich C kinase substrate is involved in the cAMP-dependent amylase release in parotid acinar cells. American journal of physiology. Gastrointestinal and liver physiology 20090601
Isoproterenol inhibits angiotensin II-stimulated proliferation and reactive oxygen species production in vascular smooth muscle cells through heme oxygenase-1. Biological & pharmaceutical bulletin 20090601
Protein kinase A-dependence of the supraspinally mediated analgesic effects of gabapentin on thermal and mechanical hypersensitivity. Journal of pharmacological sciences 20090601
The mechanism of chemokine receptor 9 internalization triggered by interleukin 2 and interleukin 4. Cellular & molecular immunology 20090601
Participation of the human sperm proteasome in the capacitation process and its regulation by protein kinase A and tyrosine kinase. Biology of reproduction 20090501
Modulation of choline kinase activity in human cancer cells observed by dynamic 31P NMR. NMR in biomedicine 20090501
Regulation of AMP-activated protein kinase by cAMP in adipocytes: roles for phosphodiesterases, protein kinase B, protein kinase A, Epac and lipolysis. Cellular signalling 20090501
Prolonged inhibition of protein kinase A results in metalloproteinase-dependent platelet GPIbalpha shedding. Thrombosis research 20090501
IL-17F-induced IL-11 release in bronchial epithelial cells via MSK1-CREB pathway. American journal of physiology. Lung cellular and molecular physiology 20090501
Enhanced Rap1 activation and insulin secretagogue properties of an acetoxymethyl ester of an Epac-selective cyclic AMP analog in rat INS-1 cells: studies with 8-pCPT-2'-O-Me-cAMP-AM. The Journal of biological chemistry 20090417
Type 2 deiodinase expression is induced by peroxisomal proliferator-activated receptor-gamma agonists in skeletal myocytes. Endocrinology 20090401
CGRP-alpha responsiveness of adult rat ventricular cardiomyocytes from normotensive and spontaneously hypertensive rats. European journal of cell biology 20090401
The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells. Molecular endocrinology (Baltimore, Md.) 20090401
Glucocorticoids and mitogen- and stress-activated protein kinase 1 inhibitors: possible partners in the combat against inflammation. Biochemical pharmacology 20090401
Interaction of dopamine D1 with NMDA NR1 receptors in rat prefrontal cortex. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090401
Protein phosphatase 2A contributes to the cardiac dysfunction induced by endotoxemia. Cardiovascular research 20090401
Rab11 and its effector Rip11 participate in regulation of insulin granule exocytosis. Genes to cells : devoted to molecular & cellular mechanisms 20090401
Expression and in vitro regulation of pituitary adenylate cyclase-activating polypeptide (pacap38) and its type I receptor (pac1-r) in the gonads of tilapia (Oreochromis mossambicus). Reproduction (Cambridge, England) 20090301
Cyclic adenosine monophosphate response element-binding protein phosphorylation and neuroprotection by 4-phenyl-1-(4-phenylbutyl) piperidine (PPBP). Anesthesia and analgesia 20090301
[A novel cell model targeted on GLP-1 receptor for application to anti-diabetic candidates screening]. Yao xue xue bao = Acta pharmaceutica Sinica 20090301
Spatial distribution of protein kinase A activity during cell migration is mediated by A-kinase anchoring protein AKAP Lbc. The Journal of biological chemistry 20090227
Interaction between protein kinase C and protein kinase A can modulate transmitter release at the rat neuromuscular synapse. Journal of neuroscience research 20090215
Regulation of relaxin 3 gene expression via cAMP-PKA in a neuroblastoma cell line. Journal of neuroscience research 20090215
Protein kinase A modulates A-type potassium currents of larval zebrafish (Danio rerio) white muscle fibres. Acta physiologica (Oxford, England) 20090201
Trafficking of GFP-AQP5 chimeric proteins conferred with unphosphorylated amino acids at their PKA-target motif ((152)SRRTS) in MDCK-II cells. The journal of medical investigation : JMI 20090201
PKA-dependent and independent cAMP signaling in 3T3-L1 fibroblasts differentiation. Molecular and cellular endocrinology 20090127
Concomitant activation of adenylyl cyclase suppresses the opposite influences of CB(1) cannabinoid receptor agonists on tyrosine hydroxylase expression. Biochemical pharmacology 20090115
Adrenomedullin-induced relaxation of rat brain pericytes is related to the reduced phosphorylation of myosin light chain through the cAMP/PKA signaling pathway. Neuroscience letters 20090102
Role of dosage-sensitive sex reversal, adrenal hypoplasia congenita, critical region on the X chromosome, gene 1 in protein kinase A- and protein kinase C-mediated regulation of the steroidogenic acute regulatory protein expression in mouse Leydig tumor cells: mechanism of action. Endocrinology 20090101
Resveratrol, a naturally occurring diphenolic compound, affects lipogenesis, lipolysis and the antilipolytic action of insulin in isolated rat adipocytes. The Journal of steroid biochemistry and molecular biology 20090101
Atorvastatin prevents carbohydrate response element binding protein activation in the fructose-fed rat by activating protein kinase A. Hepatology (Baltimore, Md.) 20090101
Effect of protein kinase C and protein kinase A inhibitors on contraction of isolated femoral arteries of SHR and Wistar rats. Physiological research 20090101
Genomic and non-genomic effect of cortisol on phagocytosis in freshwater teleost Channa punctatus: an in vitro study. Steroids 20090101
The cAMP-dependent protein kinase inhibitor H-89 attenuates the bioluminescence signal produced by Renilla Luciferase. PloS one 20090101
Inhibition of superoxide anion production by extracellular acidification in neutrophils. Cellular immunology 20090101
Hydrostatic pressure-dependent changes in cyclic AMP signaling in optic nerve head astrocytes from Caucasian and African American donors. Molecular vision 20090101
L-type channel inhibition by CB1 cannabinoid receptors is mediated by PTX-sensitive G proteins and cAMP/PKA in GT1-7 hypothalamic neurons. Cell calcium 20090101
Protein kinase Cmu plays an essential role in hypertonicity-induced heat shock protein 70 expression. Experimental & molecular medicine 20081231
Differential cAMP signaling at hippocampal output synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience 20081231
Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes. Biochemistry 20081230
The phosphodiesterase III inhibitor olprinone inhibits hippocampal glutamate release via a cGMP/PKG pathway. Neuroscience letters 20081226
State-dependent cAMP sensitivity of presynaptic function underlies metaplasticity in a hippocampal feedforward inhibitory circuit. Neuron 20081226
Role of the hyperpolarization-activated current Ih in somatosensory neurons. The Journal of physiology 20081215
Initial and extended inflammatory messages of the nongenomic signaling pathway of the TCDD-activated Ah receptor in U937 macrophages. Archives of biochemistry and biophysics 20081215
Simple device for multiplexed electrophoretic separations using gradient elution moving boundary electrophoresis with channel current detection. Analytical chemistry 20081215
Diurnal variation in phagocytic activity of splenic phagocytes in freshwater teleost Channa punctatus: melatonin and its signaling mechanism. The Journal of endocrinology 20081201
cAMP-mediated beta-adrenergic signaling negatively regulates Gq-coupled receptor-mediated fetal gene response in cardiomyocytes. Journal of molecular and cellular cardiology 20081201
Involvement of regulatory elements on corticotropin-releasing factor gene promoter in hypothalamic 4B cells. Journal of endocrinological investigation 20081201
Tonic activity of Galpha-gustducin regulates taste cell responsivity. FEBS letters 20081112
Epac activation, altered calcium homeostasis and ventricular arrhythmogenesis in the murine heart. Pflugers Archiv : European journal of physiology 20081101
Insulin stimulates interleukin-6 expression and release in LS14 human adipocytes through multiple signaling pathways. Endocrinology 20081101
The role of JUN in the regulation of PRKCC-mediated STAR expression and steroidogenesis in mouse Leydig cells. Journal of molecular endocrinology 20081101
Inhibition of interleukin-1beta-induced matrix metalloproteinases 1 and 13 production in human osteoarthritic chondrocytes by prostaglandin D2. Arthritis and rheumatism 20081101
The effect of cAMP signaling on the longitudinal extension of spinal sensory neurons in the chicken embryo. Journal of anatomy 20081101
In vitro brain tyrosine hydroxylase activation in catfish Heteropneustes fossilis (Bloch): seasonal changes in involvement of cAMP-dependent protein kinase A and Ca2+ -dependent protein kinase C. Indian journal of experimental biology 20081101
Inhibitory effect of somatostatin on prostaglandin E2 synthesis by primary neonatal rat glial cells. Regulatory peptides 20081009
Rapid fluorescent assay for screening drugs on Leishmania amastigotes. Journal of microbiological methods 20081001
Branched-chain amino acids and arginine suppress MaFbx/atrogin-1 mRNA expression via mTOR pathway in C2C12 cell line. Biochimica et biophysica acta 20081001
Akt and ERK1/2 pathways are components of the vasopressin signaling network in rat native IMCD. American journal of physiology. Renal physiology 20081001
Rotenone inhibits delayed rectifier K+ current via a protein kinase A-dependent mechanism. Neuroreport 20080917
AKAP150-anchored PKA activity is important for LTD during its induction phase. The Journal of physiology 20080901
Phosphorylation of 5-lipoxygenase at ser523 by protein kinase A determines whether pioglitazone and atorvastatin induce proinflammatory leukotriene B4 or anti-inflammatory 15-epi-lipoxin a4 production. Journal of immunology (Baltimore, Md. : 1950) 20080901
The influence of methylmercury on the nitric oxide production of alveolar macrophages. Toxicology and industrial health 20080901
Rap1 activation plays a regulatory role in pancreatic amylase secretion. The Journal of biological chemistry 20080829
A novel Epac-Rap-PP2A signaling module controls cAMP-dependent Akt regulation. The Journal of biological chemistry 20080822
H89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide) induces reduction of myosin regulatory light chain phosphorylation and inhibits cell proliferation. European journal of pharmacology 20080820
Susceptibility of Plasmodium falciparum cyclic AMP-dependent protein kinase and its mammalian homologue to the inhibitors. Molecular and biochemical parasitology 20080801
Constitutively active protein kinase A qualitatively mimics the effects of follicle-stimulating hormone on granulosa cell differentiation. Molecular endocrinology (Baltimore, Md.) 20080801
Reciprocal stimulation of decay between serotonergic facilitation and depression of synaptic transmission. Journal of neurophysiology 20080801
MAP-kinase-activated protein kinase 2 expression and activity is induced after neuronal depolarization. The European journal of neuroscience 20080801
Protein kinase a mediates activity-dependent Kv4.2 channel trafficking. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080723
Cyclic adenosine 3',5'-monophosphate responsive element binding protein phosphorylation is required but not sufficient for activation of corticotropin-releasing hormone transcription. Endocrinology 20080701
Activation of amygdaloid PKC pathway is necessary for conditioned cues-provoked cocaine memory performance. Neurobiology of learning and memory 20080701
Ouabain-induced stimulation of sodium-hydrogen exchange in rat optic nerve astrocytes. American journal of physiology. Cell physiology 20080701
d-Amphetamine inhibits inwardly rectifying potassium channels in Xenopus oocytes expression system. Neurotoxicology 20080701
Regulation of ERK1/2 by the C. elegans muscarinic acetylcholine receptor GAR-3 in Chinese hamster ovary cells. Molecules and cells 20080630
Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition. The EMBO journal 20080618
Protein kinase C is a common component of CGRP receptor desensitization induced by distinct agonists. European journal of pharmacology 20080610
Selenoprotein T is a PACAP-regulated gene involved in intracellular Ca2+ mobilization and neuroendocrine secretion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080601
Prolonged heterologous beta2-adrenoceptor desensitization promotes proasthmatic airway smooth muscle function via PKA/ERK1/2-mediated phosphodiesterase-4 induction. American journal of physiology. Lung cellular and molecular physiology 20080601
Interleukin-6 stimulates lipolysis in porcine adipocytes. Endocrine 20080601
Quercetin augments TRAIL-induced apoptotic death: involvement of the ERK signal transduction pathway. Biochemical pharmacology 20080515
PDE4 inhibitor, roflumilast protects cardiomyocytes against NO-induced apoptosis via activation of PKA and Epac dual pathways. Cellular signalling 20080501
cAMP-dependent protein kinase regulates the mitochondrial import of the nuclear encoded NDUFS4 subunit of complex I. Cellular signalling 20080501
Gabapentin activates ROMK1 channels by a protein kinase A (PKA)-dependent mechanism. British journal of pharmacology 20080501
Rationally designed PKA inhibitors for positron emission tomography: Synthesis and cerebral biodistribution of N-(2-(4-bromocinnamylamino)ethyl)-N-[11C]methyl-isoquinoline-5-sulfonamide. Bioorganic & medicinal chemistry 20080501
Enhancement of long-term potentiation by brain-derived neurotrophic factor requires adenosine A2A receptor activation by endogenous adenosine. Neuropharmacology 20080501
Protein kinase A-mediated CREB phosphorylation is an oxidant-induced survival pathway in alveolar type II cells. Apoptosis : an international journal on programmed cell death 20080501
Growth factor regulation of estrogen receptor coregulator PELP1 functions via Protein Kinase A pathway. Molecular cancer research : MCR 20080501
MSK activation and physiological roles. Frontiers in bioscience : a journal and virtual library 20080501
Sustained morphine treatment augments basal CGRP release from cultured primary sensory neurons in a Raf-1 dependent manner. European journal of pharmacology 20080428
Identification of 4-(4-aminopiperidin-1-yl)-7H-pyrrolo[2,3-d]pyrimidines as selective inhibitors of protein kinase B through fragment elaboration. Journal of medicinal chemistry 20080410
Expression of SH2D2A in T-cells is regulated both at the transcriptional and translational level. Molecular immunology 20080401
Effect of corosolic acid on gluconeogenesis in rat liver. Diabetes research and clinical practice 20080401
Prostaglandin F2-alpha receptor regulation in human uterine myocytes. Molecular human reproduction 20080401
Mitogen- and stress-activated kinase 1-mediated histone H3 phosphorylation is crucial for cell transformation. Cancer research 20080401
GABAC-receptor stimulation activates cAMP-dependent protein kinase via A-kinase anchoring protein 220. Journal of pharmacological sciences 20080401
Peripheral involvement of PKA and PKC in subcutaneous bee venom-induced persistent nociception, mechanical hyperalgesia, and inflammation in rats. Pain 20080301
Neuropeptide Y reduces acetylcholine release and vagal bradycardia via a Y2 receptor-mediated, protein kinase C-dependent pathway. Journal of molecular and cellular cardiology 20080301
Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway. Journal of neurochemistry 20080301
Genistein, a plant-derived isoflavone, counteracts the antilipolytic action of insulin in isolated rat adipocytes. The Journal of steroid biochemistry and molecular biology 20080301
Differential regulation of ErbB2 expression by cAMP-dependent protein kinase in tamoxifen-resistant breast cancer cells. Archives of pharmacal research 20080301
ICER-1gamma overexpression drives palmitate-mediated connexin36 down-regulation in insulin-secreting cells. The Journal of biological chemistry 20080227
Tyrosine phosphorylation of a 38-kDa capacitation-associated buffalo (Bubalus bubalis) sperm protein is induced by L-arginine and regulated through a cAMP/PKA-independent pathway. International journal of andrology 20080201
Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. European journal of pharmacology 20080114
Activation of protein kinase A (PKA) signaling mitigates the antiproliferative and antiinvasive effects of alpha-difluoromethylornithine in breast cancer cells. Breast cancer research and treatment 20080101
Steroidogenesis in BeWo cells: role of protein kinase A and benzodiazepines. The international journal of biochemistry & cell biology 20080101
Modulation of Ca2+ channel current by mu opioid receptors in prefrontal cortex pyramidal neurons in rats. Acta neurobiologiae experimentalis 20080101
Role of PDK1 in regulation of gastric acid secretion. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proceedings of the National Academy of Sciences of the United States of America 20071218
The selectivity of protein kinase inhibitors: a further update. The Biochemical journal 20071215
A citrus polymethoxy flavonoid, nobiletin inhibits sebum production and sebocyte proliferation, and augments sebum excretion in hamsters. The Journal of investigative dermatology 20071201
Up-regulation of cyclooxygenase-2 by cobalt chloride-induced hypoxia is mediated by phospholipase D isozymes in human astroglioma cells. Biochimica et biophysica acta 20071201
RelB, a new partner of aryl hydrocarbon receptor-mediated transcription. Molecular endocrinology (Baltimore, Md.) 20071201
Rapid increase of glial glutamate uptake via blockade of the protein kinase A pathway. Glia 20071201
Regulation of protein kinase D activity in adult myocardium: novel counter-regulatory roles for protein kinase Cepsilon and protein kinase A. Journal of molecular and cellular cardiology 20071201
Prostaglandin E2 sensitizes primary sensory neurons to histamine. Neuroscience 20071130
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. Nature 20071129
Stimulus-induced phosphorylation of vacuolar H(+)-ATPase by protein kinase A. The Journal of biological chemistry 20071116
Fibroblast apoptosis induced by Porphyromonas gingivalis is stimulated by a gingipain and caspase-independent pathway that involves apoptosis-inducing factor. Cellular microbiology 20071101
Alpha2-adrenergic receptors activate cyclic AMP-response element-binding protein through arachidonic acid metabolism and protein kinase A in a subtype-specific manner. Journal of neurochemistry 20071101
Hydrogen peroxide stimulates chloride secretion in primary inner medullary collecting duct cells via mPGES-1-derived PGE2. American journal of physiology. Renal physiology 20071101
Effect of PAR1 agonist on acetylcholine secretion in a newly formed neuromuscular synapse in mice. Bulletin of experimental biology and medicine 20071101
Opposite effects of two PKA inhibitors on cAMP inhibition of IGF-I-induced oligodendrocyte development: a problem of unspecificity? Brain research 20071031
Activation of protein kinases A and C promoted proliferation of chicken primordial germ cells. Animal reproduction science 20071001
Studies on the cell treatment conditions to elicit lipolytic responses from 3T3-L1 adipocytes to TCDD, 2,3,7,8-tetrachlorodibenzo-p-dioxin. Journal of cellular biochemistry 20071001
Regulation of matrix Gla protein by parathyroid hormone in MC3T3-E1 osteoblast-like cells involves protein kinase A and extracellular signal-regulated kinase pathways. Journal of cellular biochemistry 20071001
Evidence for amylase release by cGMP via cAMP-dependent protein kinase in rat parotid acinar cells. Archives of oral biology 20071001
PGE2 inhibits apoptosis in human adenocarcinoma Caco-2 cell line through Ras-PI3K association and cAMP-dependent kinase A activation. American journal of physiology. Gastrointestinal and liver physiology 20071001
Rosmarinic acid induces melanogenesis through protein kinase A activation signaling. Biochemical pharmacology 20071001
Intermittent hypoxia changes HIF-1alpha phosphorylation pattern in endothelial cells: unravelling of a new PKA-dependent regulation of HIF-1alpha. Biochimica et biophysica acta 20071001
Activation of exchange protein directly activated by cyclic adenosine monophosphate and protein kinase A regulate common and distinct steps in promoting plasma membrane exocytic and granule-to-granule fusions in rat islet beta cells. Pancreas 20071001
Secretion of apolipoprotein E from macrophages occurs via a protein kinase A and calcium-dependent pathway along the microtubule network. Circulation research 20070914
Prostacyclin inhibits endothelial cell XIAP ubiquitination and degradation. Journal of cellular physiology 20070901
Different kinases regulate activation of voltage-dependent calcium channels by depolarization in GH3 cells. American journal of physiology. Cell physiology 20070901
Evaluation of broad spectrum protein kinase inhibitors to probe the architecture of the malarial cyclin dependent protein kinase Pfmrk. Bioorganic & medicinal chemistry letters 20070901
Ca2+/calmodulin kinase II increases ryanodine binding and Ca2+-induced sarcoplasmic reticulum Ca2+ release kinetics during beta-adrenergic stimulation. Journal of molecular and cellular cardiology 20070901
In spermatozoa, Stat1 is activated during capacitation and the acrosomal reaction. Reproduction (Cambridge, England) 20070901
Effects of celecoxib on voltage-gated calcium channel currents in rat pheochromocytoma (PC12) cells. Pharmacological research 20070901
A brief, but repeated, swimming protocol is sufficient to overcome amyloid beta-protein inhibition of hippocampal long-term potentiation. The European journal of neuroscience 20070901
Intracellular signaling molecules involved in vasoactive intestinal peptide-mediated wound healing in human bronchial epithelial cells. Peptides 20070901
beta-adrenoceptor agonists downregulate adiponectin, but upregulate adiponectin receptor 2 and tumor necrosis factor-alpha expression in adipocytes. European journal of pharmacology 20070813
Proteasome function is regulated by cyclic AMP-dependent protein kinase through phosphorylation of Rpt6. The Journal of biological chemistry 20070803
Upregulation of the glutamine transporter through transactivation mediated by cAMP/protein kinase A signals toward exacerbation of vulnerability to oxidative stress in rat neocortical astrocytes. Journal of cellular physiology 20070801
Follicle-stimulating hormone increases tuberin phosphorylation and mammalian target of rapamycin signaling through an extracellular signal-regulated kinase-dependent pathway in rat granulosa cells. Endocrinology 20070801
Role of calcium messenger systems in ACTH-induced cortisol production in bovine adrenal fasciculo-reticularis cells. Endocrine journal 20070801
Norepinephrine suppresses wound macrophage phagocytic efficiency through alpha- and beta-adrenoreceptor dependent pathways. Surgery 20070801
Testosterone upregulation of tissue type plasminogen activator expression in Sertoli cells : tPA expression in Sertoli cells. Endocrine 20070801
Sensitisation of TRPV1 in rat sensory neurones by activation of SNSRs. Neuroscience letters 20070705
Role of MAPK and PKA in regulation of rbOCT2-mediated renal organic cation transport. American journal of physiology. Renal physiology 20070701
Protein kinase A is activated by the n-3 polyunsaturated fatty acid eicosapentaenoic acid in rat ventricular muscle. The Journal of physiology 20070701
IGF-I inhibition of apoptosis is associated with decreased expression of prostate apoptosis response-4. The Journal of endocrinology 20070701
Beta-amyloid blocks high frequency stimulation induced LTP but not nicotine enhanced LTP. Neuropharmacology 20070701
Bidirectional synaptic plasticity at nociceptive afferents in the rat central amygdala. The Journal of physiology 20070615
Dual regulation of the ATP-sensitive potassium channel by caffeine. American journal of physiology. Cell physiology 20070601
Novel mechanism of cyclic AMP mediated extracellular signal regulated kinase activation in an intestinal cell line. Cellular signalling 20070601
Asbestos-mediated CREB phosphorylation is regulated by protein kinase A and extracellular signal-regulated kinases 1/2. American journal of physiology. Lung cellular and molecular physiology 20070601
Dissociation between the translocation and the activation of Akt in fMLP-stimulated human neutrophils--effect of prostaglandin E2. Journal of leukocyte biology 20070601
Adrenergic control of a constitutively active acetylcholine-regulated potassium current in canine atrial cardiomyocytes. Cardiovascular research 20070601
Synaptic plasticity in myenteric neurons of the guinea-pig distal colon: presynaptic mechanisms of inflammation-induced synaptic facilitation. The Journal of physiology 20070601
Golgi complex disassembly caused by light-activated calphostin C involves MAPK and PKA. Tissue & cell 20070601
Rapid evolution of 6-phenylpurine inhibitors of protein kinase B through structure-based design. Journal of medicinal chemistry 20070517
Shrinkage insensitivity of NKCC1 in myosin II-depleted cytoplasts from Ehrlich ascites tumor cells. American journal of physiology. Cell physiology 20070501
Expression of islet inducible nitric oxide synthase and inhibition of glucose-stimulated insulin release after long-term lipid infusion in the rat is counteracted by PACAP27. American journal of physiology. Endocrinology and metabolism 20070501
Effects of monocarboxylic acid-derived Cl- channel blockers on depolarization-activated potassium currents in rat ventricular myocytes. Experimental physiology 20070501
Schwann cells express IP prostanoid receptors coupled to an elevation in intracellular cyclic AMP. Journal of neuroscience research 20070501
Muscarinic receptor-independent activation of cyclic adenosine monophosphate-dependent protein kinase in rostral ventrolateral medulla underlies the sympathoexcitatory phase of cardiovascular responses during mevinphos intoxication in the rat. Shock (Augusta, Ga.) 20070501
Stimulation of the cAMP pathway protects cultured cerebellar granule neurons against alcohol-induced cell death by activating the neuronal nitric oxide synthase (nNOS) gene. Brain research 20070427
Acute regulation of mUT-A3 urea transporter expressed in a MDCK cell line. American journal of physiology. Renal physiology 20070401
Altered pH(i) regulation and Na(+)/HCO3(-) transporter activity in choroid plexus of cilia-defective Tg737(orpk) mutant mouse. American journal of physiology. Cell physiology 20070401
Signalling mechanisms in contraction-mediated stimulation of intracellular NO production in cat ventricular myocytes. The Journal of physiology 20070401
The role of c-AMP-dependent protein kinase in spinal cord and post synaptic dorsal column neurons in a rat model of visceral pain. Neurochemistry international 20070401
G-protein-coupled receptor 30 mediates estrogen's nongenomic effects after hemorrhagic shock and trauma. The American journal of pathology 20070401
G protein-coupled receptor 30-dependent protein kinase A pathway is critical in nongenomic effects of estrogen in attenuating liver injury after trauma-hemorrhage. The American journal of pathology 20070401
Regulation of Leydig cell steroidogenesis by extracellular signal-regulated kinase 1/2: role of protein kinase A and protein kinase C signaling. The Journal of endocrinology 20070401
A novel role of VIP in colonic motility function: induction of excitation-transcription coupling in smooth muscle cells. Gastroenterology 20070401
Signaling mechanisms leading to regulation of proliferation and differentiation of the mesenchymal chondrogenic cell line RCJ3.1C5.18 in response to IGF-I. Journal of molecular endocrinology 20070401
Upregulation of AKT1 protein expression in forskolin-stimulated macrophage: evidence from ChIP analysis that CREB binds to and activates the AKT1 promoter. Journal of cellular biochemistry 20070301
Estradiol and progesterone synthesis in human placenta is stimulated by calcitriol. The Journal of steroid biochemistry and molecular biology 20070301
Beta-adrenergic enhancement of sarcoplasmic reticulum calcium leak in cardiac myocytes is mediated by calcium/calmodulin-dependent protein kinase. Circulation research 20070216
Ligusticum chuanxiong prevents rat pheochromocytoma cells from serum deprivation-induced apoptosis through a protein kinase A-dependent pathway. Journal of ethnopharmacology 20070212
Activation dependent expression of MMPs in peripheral blood mononuclear cells involves protein kinase A. Molecular and cellular biochemistry 20070201
Direct modulation of Ca(2+)-activated K(+) current by H-89 in rabbit coronary arterial smooth muscle cells. Vascular pharmacology 20070201
(+/-)3,4-Methylenedioxyamphetamine elicits action potential bursts in a central snail neuron. Experimental neurology 20070201
The possible mechanisms by which phanoside stimulates insulin secretion from rat islets. The Journal of endocrinology 20070201
Gonadotropin-dependent regulation of bovine pituitary adenylate cyclase-activating polypeptide in ovarian follicles prior to ovulation. Reproduction (Cambridge, England) 20070201
Microarray-based kinase inhibition assay by gold nanoparticle probes. Analytical chemistry 20070115
H-89 potentiates adipogenesis in 3T3-L1 cells by activating insulin signaling independently of protein kinase A. Life sciences 20070109
Upregulation of substance P receptor expression by calcitonin gene-related peptide, a possible cooperative action of two neuropeptides involved in airway inflammation. Pulmonary pharmacology & therapeutics 20070101
Cellular mechanisms underlying prostaglandin-induced transient cAMP signals near the plasma membrane of HEK-293 cells. American journal of physiology. Cell physiology 20070101
Immediate early gene IEX-1 induces astrocytic differentiation of U87-MG human glioma cells. Journal of cellular biochemistry 20070101
Dopaminergic and adrenergic toxicities on SK-N-MC human neuroblastoma cells are mediated through G protein signaling and oxidative stress. Apoptosis : an international journal on programmed cell death 20070101
Stimulation of fibroblast proliferation by neokyotorphin requires Ca influx and activation of PKA, CaMK II and MAPK/ERK. The FEBS journal 20070101
Protective effects of chronic lithium treatment against spatial memory retention deficits induced by the protein kinase AII inhibitor H-89 in rats. Pharmacology 20070101
Genital sensory stimulation shifts estradiol intraoviductal signaling from nongenomic to genomic pathways, independently from prolactin surges. Biological research 20070101
Regulation of the prepronociceptin gene and its effect on neuronal differentiation. Gene 20061215
Maximal beta3-adrenergic regulation of lipolysis involves Src and epidermal growth factor receptor-dependent ERK1/2 activation. The Journal of biological chemistry 20061208
ERK1/2 and p38-MAPK signalling pathways, through MSK1, are involved in NF-kappaB transactivation during oxidative stress in skeletal myoblasts. Cellular signalling 20061201
Protein kinase A-mediated phosphorylation contributes to enhanced contraction observed in mice that overexpress beta-adrenergic receptor kinase-1. The Journal of pharmacology and experimental therapeutics 20061201
Control of oestradiol secretion and of cytochrome P450 aromatase messenger ribonucleic acid accumulation by FSH involves different intracellular pathways in oestrogenic bovine granulosa cells in vitro. Reproduction (Cambridge, England) 20061201
Intra-hippocampal inhibition of protein kinase AII attenuates morphine-induced conditioned place preference. Pharmacology, biochemistry, and behavior 20061201
Effects of (+)-eudesmin from the stem bark of magnolia kobus DC. var. borealis Sarg. on neurite outgrowth in PC12 cells. Archives of pharmacal research 20061201
[The mechanism of ginsenosides Rg1 and Rb1 promoting glutamic acid release from PC12 cells]. Yao xue xue bao = Acta pharmaceutica Sinica 20061201
Triphenyltin impairs a protein kinase A (PKA)-dependent increase of cytosolic Na+ and Ca2+ and PKA-independent increase of cytosolic Ca2+ associated with insulin secretion in hamster pancreatic beta-cells. Toxicology and applied pharmacology 20061101
Adenosine A2A receptors are expressed in human atrial myocytes and modulate spontaneous sarcoplasmic reticulum calcium release. Cardiovascular research 20061101
Stimulation of melanogenesis by scoparone in B16 melanoma cells. Acta pharmacologica Sinica 20061101
Signal transduction mechanisms involved in in vitro ram sperm capacitation. Reproduction (Cambridge, England) 20061101
Dopamine D(2) receptor expression and regulation of gonadotropin alpha-subunit gene in clonal gonadotroph LbetaT2 cells. Molecular and cellular endocrinology 20061019
Synthesis of highly substituted dibenzo[b,f]azocines and their evaluation as protein kinase inhibitors. Bioorganic & medicinal chemistry letters 20061015
Real-time analysis of cAMP-mediated regulation of ciliary motility in single primary human airway epithelial cells. Journal of cell science 20061015
Regulation of UT-A1-mediated transepithelial urea flux in MDCK cells. American journal of physiology. Cell physiology 20061001
L-type calcium channel alpha-subunit and protein kinase inhibitors modulate Rem-mediated regulation of current. American journal of physiology. Heart and circulatory physiology 20061001
NNK activates ERK1/2 and CREB/ATF-1 via beta-1-AR and EGFR signaling in human lung adenocarcinoma and small airway epithelial cells. International journal of cancer 20061001
Role of kinases and G-proteins in the hyposmotic stimulation of cardiac IKs. Biochimica et biophysica acta 20061001
PGE2 up-regulates EGF-like growth factor biosynthesis in human granulosa cells: new insights into the coordination between PGE2 and LH in ovulation. Molecular human reproduction 20061001
Cell signaling and trafficking of human melanocortin receptors in real time using two-photon fluorescence and confocal laser microscopy: differentiation of agonists and antagonists. Chemical biology & drug design 20061001
Beta-arrestin2-mediated internalization of mammalian odorant receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060927
Role of store-operated calcium channels and calcium sensitization in normoxic contraction of the ductus arteriosus. Circulation 20060926
TGF-beta regulates differentially the proliferation of fetal and adult human skin fibroblasts via the activation of PKA and the autocrine action of FGF-2. Cellular signalling 20060901
Effects of hyposmotic stress on exocytosis in isolated turbot, Scophthalmus maximus, hepatocytes. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20060901
cAMP synthesis and degradation by phagosomes regulate actin assembly and fusion events: consequences for mycobacteria. Journal of cell science 20060901
gamma-Hydroxybutyrate induces cyclic AMP-responsive element-binding protein phosphorylation in mouse hippocampus: an involvement of GABA(B) receptors and cAMP-dependent protein kinase activation. Neuroscience 20060811
Protease-activated receptor-2 activation exaggerates TRPV1-mediated cough in guinea pigs. Journal of applied physiology (Bethesda, Md. : 1985) 20060801
Distinct regulation by steroids of messenger RNAs for FSHR and CYP19A1 in bovine granulosa cells. Biology of reproduction 20060801
Dopamine presynaptically depresses fast inhibitory synaptic transmission via D4 receptor-protein kinase A pathway in the rat dorsolateral septal nucleus. Journal of neurophysiology 20060801
Proteomic analysis of rat liver phosphoproteins after treatment with protein kinase inhibitor H89 (N-(2-[p-bromocinnamylamino-]ethyl)-5-isoquinolinesulfonamide). The Journal of pharmacology and experimental therapeutics 20060801
Cimetidine induces interleukin-18 production through H2-agonist activity in monocytes. Molecular pharmacology 20060801
A PKA survival pathway inhibited by DPT-PKI, a new specific cell permeable PKA inhibitor, is induced by T. annulata in parasitized B-lymphocytes. Apoptosis : an international journal on programmed cell death 20060801
H-89 inhibits transient outward and inward rectifier potassium currents in isolated rat ventricular myocytes. British journal of pharmacology 20060801
The role of constitutive PKA-mediated phosphorylation in the regulation of basal I(Ca) in isolated rat cardiac myocytes. British journal of pharmacology 20060801
Negative regulation of MHC class II gene expression by CXCR4. Experimental hematology 20060801
ERK1/2 control phosphorylation and protein level of cAMP-responsive element-binding protein: a key role in glucose-mediated pancreatic beta-cell survival. Diabetes 20060801
Signalling pathways involved in hypertonicity- and acidification-induced activation of Na+/H+ exchange in trout hepatocytes. The Journal of experimental biology 20060801
Wound repair and proliferation of bronchial epithelial cells enhanced by bombesin receptor subtype 3 activation. Peptides 20060701
Urea flux across MDCK-mUT-A2 monolayers is acutely sensitive to AVP, cAMP, and [Ca2+]i. American journal of physiology. Renal physiology 20060701
Hydroxyurea induces the eNOS-cGMP pathway in endothelial cells. Blood 20060701
Adenosine A2A receptor stimulation decreases GAT-1-mediated GABA uptake in the globus pallidus of the rat. Neuropharmacology 20060701
2-Hydroxyestradiol-17beta-induced oocyte maturation: involvement of cAMP-protein kinase A and okadaic acid-sensitive protein phosphatases, and their interplay in oocyte maturation in the catfish Heteropneustes fossilis. The Journal of experimental biology 20060701
An active protein kinase A (PKA) is involved in meiotic arrest of rat growing oocytes. Reproduction (Cambridge, England) 20060701
Involvement of the adenylyl cyclase/protein kinase A signaling pathway in the stimulatory effect of PACAP on frog adrenocortical cells. Annals of the New York Academy of Sciences 20060701
Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1alpha gene transcription: an autoregulatory loop controls PGC-1alpha expression in adipocytes via peroxisome proliferator-activated receptor-gamma coactivation. Endocrinology 20060601
cAMP-PKA signaling pathway regulates bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts. International immunopharmacology 20060601
Adiponectin suppression of high-glucose-induced reactive oxygen species in vascular endothelial cells: evidence for involvement of a cAMP signaling pathway. Diabetes 20060601
NMR-based quality control approach for the identification of false positives and false negatives in high throughput screening. Current drug discovery technologies 20060601
Adiponectin stimulates proliferation and cytokine secretion in colonic epithelial cells. Regulatory peptides 20060515
Iron released by sodium nitroprusside contributes to heme oxygenase-1 induction via the cAMP-protein kinase A-mitogen-activated protein kinase pathway in RAW 264.7 cells. Molecular pharmacology 20060501
Parathyroid hormone increases beta-catenin levels through Smad3 in mouse osteoblastic cells. Endocrinology 20060501
Inhibition of superoxide anion and elastase release in human neutrophils by 3'-isopropoxychalcone via a cAMP-dependent pathway. British journal of pharmacology 20060501
Adrenomedullin in the rostral ventrolateral medulla inhibits baroreflex control of heart rate: a role for protein kinase A. British journal of pharmacology 20060501
Ischemic preconditioning prevents calpain-mediated impairment of Na+/K+-ATPase activity during early reperfusion. Cardiovascular research 20060501
Chronic acidosis-induced growth retardation is mediated by proton-induced expression of Gs protein. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20060501
Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation. The Journal of biological chemistry 20060421
Prolonged activation of cAMP-response element-binding protein and ATF-2 needed for nicotine-triggered elevation of tyrosine hydroxylase gene transcription in PC12 cells. The Journal of biological chemistry 20060414
Estrogen induces estrogen receptor alpha-dependent cAMP response element-binding protein phosphorylation via mitogen activated protein kinase pathway in basal forebrain cholinergic neurons in vivo. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060412
Regulation of cyclin D2 and the cyclin D2 promoter by protein kinase A and CREB in lymphocytes. Oncogene 20060406
Dopamine regulation of amiloride-sensitive sodium channels in lung cells. American journal of physiology. Lung cellular and molecular physiology 20060401
Acute, nongenomic effect of thyroid hormones in preventing calcium overload in newborn rat cardiocytes. Journal of cellular physiology 20060401
Glycogen synthase kinase-3 phosphorylation, T-cell factor signaling activation, and cell morphology change following stimulation of thromboxane receptor alpha. The Journal of pharmacology and experimental therapeutics 20060401
The role of prostaglandin E receptor-dependent signaling via cAMP in Mdr1b gene activation in primary rat hepatocyte cultures. The Journal of pharmacology and experimental therapeutics 20060401
The immunosuppressive effects of ciprofloxacin during human mixed lymphocyte reaction. Clinical immunology (Orlando, Fla.) 20060401
Different pathways for activation of extracellular signal-regulated kinase through thromboxane A2 receptor isoforms. Biological & pharmaceutical bulletin 20060401
Characterization of recombinant human cardiac KCNQ1/KCNE1 channels (I (Ks)) stably expressed in HEK 293 cells. The Journal of membrane biology 20060401
Direct inhibition of a PKA inhibitor, H-89 on KV channels in rabbit coronary arterial smooth muscle cells. Biochemical and biophysical research communications 20060324
Role of PDE3B in insulin-induced glucose uptake, GLUT-4 translocation and lipogenesis in primary rat adipocytes. Cellular signalling 20060301
Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblasts. Bone 20060301
Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists. Biology of reproduction 20060301
Involvement of cAMP/cAMP-dependent protein kinase signaling pathway in regulation of Na+,K+-ATPase upon activation of opioid receptors by morphine. Molecular pharmacology 20060301
Dedifferentiation of adult monkey Sertoli cells through activation of extracellularly regulated kinase 1/2 induced by heat treatment. Endocrinology 20060301
Calcium signaling stimulates translation of HIF-alpha during hypoxia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301
Stimulation of pancreatic beta-cell replication by incretins involves transcriptional induction of cyclin D1 via multiple signalling pathways. The Journal of endocrinology 20060301
Exendin-4 induction of cyclin D1 expression in INS-1 beta-cells: involvement of cAMP-responsive element. The Journal of endocrinology 20060301
The role of adenosine A2A and A3 receptors on the differential modulation of norepinephrine and neuropeptide Y release from peripheral sympathetic nerve terminals. Journal of neurochemistry 20060301
The protein kinase A inhibitor, H-89, directly inhibits KATP and Kir channels in rabbit coronary arterial smooth muscle cells. Biochemical and biophysical research communications 20060224
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT(7) serotonin receptor. European journal of pharmacology 20060217
The signal transduction pathway for the dopamine D1 receptor in the guinea-pig cochlea. Neuroscience 20060201
The neuropeptide proctolin potentiates contractions and reduces cGMP concentration via a PKC-dependent pathway. The Journal of experimental biology 20060201
Activation of ERK1/2 and TNF-alpha production are mediated by calcium/calmodulin, and PKA signaling pathways during Mycobacterium bovis infection. The Journal of infection 20060201
Expression and localization of PCSK9 in rat hepatic cells. Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201
Basal lipolysis in epididymal fat cells from streptozotocin-induced diabetic rats. Journal of nutritional science and vitaminology 20060201
Modulation of monocarboxylic acid transporter-1 kinetic function by the cAMP signaling pathway in rat brain endothelial cells. The Journal of biological chemistry 20060127
Protein kinase A-mediated phosphorylation modulates cytochrome c oxidase function and augments hypoxia and myocardial ischemia-related injury. The Journal of biological chemistry 20060127
beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. The Journal of biological chemistry 20060113
Impact of inhibition of Qo site of mitochondrial complex III with myxothiazol on persistent sodium currents via superoxide and protein kinase C in rat hippocampal CA1 cells. Neurobiology of disease 20060101
Cyclooxygenase-2 induction by bradykinin in aortic vascular smooth muscle cells. American journal of physiology. Heart and circulatory physiology 20060101
Enhancement of Ca2+-regulated exocytosis by indomethacin in guinea-pig antral mucous cells: arachidonic acid accumulation. Experimental physiology 20060101
Fibroblast growth factor 2 applied to the optic nerve after axotomy up-regulates BDNF and TrkB in ganglion cells by activating the ERK and PKA signaling pathways. Journal of neurochemistry 20060101
Hyperactivated motility in rhesus macaque (Macaca mulatta) spermatozoa. Journal of andrology 20060101
Effects of luteinizing hormone on peroxisome proliferator-activated receptor gamma in the rat ovary before and after the gonadotropin surge. Reproduction (Cambridge, England) 20060101
Effect of epidermal growth factor and prostaglandin on the expression of aromatase (CYP19) in human adrenocortical carcinoma cell line NCI-H295R cells. The Journal of endocrinology 20060101
Signalling pathways evoked by alpha1-adrenoceptors in human melanoma cells. Cell biochemistry and function 20060101
Regulation of glutamatergic signalling by PACAP in the mammalian suprachiasmatic nucleus. BMC neuroscience 20060101
Regulation of CD93 cell surface expression by protein kinase C isoenzymes. Microbiology and immunology 20060101
Changes in membrane lipid order with capacitation in rhesus macaque (Macaca mulatta) spermatozoa. Journal of andrology 20060101
The many faces of H89: a review. Cardiovascular drug reviews 20060101
[Mechanisms of diabetes-induced impairements of serotonin release from rat brain synaptosomes: effect of nicotinamide]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20060101
The cAMP pathway regulates both transcription and activity of the paired homeobox transcription factor Phox2a required for development of neural crest-derived and central nervous system-derived catecholaminergic neurons. The Journal of biological chemistry 20051209
Divergent action of calcium channel blockers on ATP-binding cassette protein expression. Journal of cardiovascular pharmacology 20051201
Thyroid-stimulating hormone stimulates interleukin-6 release from 3T3-L1 adipocytes through a cAMP-protein kinase A pathway. Obesity research 20051201
Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation. The Journal of biological chemistry 20051118
Glucose represses connexin36 in insulin-secreting cells. Journal of cell science 20051115
Role of the redox protein thioredoxin in cytoprotective mechanism evoked by (-)-deprenyl. Molecular pharmacology 20051101
The cAMP signalling pathway activates CREB through PKA, p38 and MSK1 in NIH 3T3 cells. Cellular signalling 20051101
Melatonin inhibits hippocampal long-term potentiation. The European journal of neuroscience 20051101
Prostaglandin E2 drives cyclooxygenase-2 expression via cyclic AMP response element activation in human pancreatic cancer cells. Cancer biology & therapy 20051101
Globular adiponectin decreases leptin-induced tumor necrosis factor-alpha expression by murine macrophages: involvement of cAMP-PKA and MAPK pathways. Cellular immunology 20051101
Secretin differentially sensitizes rat pancreatic acini to the effects of supramaximal stimulation with caerulein. American journal of physiology. Gastrointestinal and liver physiology 20051001
Nitric oxide inhibits cAMP-dependent CFTR trafficking in intestinal epithelial cells. American journal of physiology. Gastrointestinal and liver physiology 20051001
Inhibition of the protein kinase A alters the degradation of the high-affinity phosphate transporter Pho84 in Saccharomyces cerevisiae. Current genetics 20051001
Stimulation of GCMa transcriptional activity by cyclic AMP/protein kinase A signaling is attributed to CBP-mediated acetylation of GCMa. Molecular and cellular biology 20051001
Thyroid hormone-induced morphological differentiation and maturation of astrocytes involves activation of protein kinase A and ERK signalling pathway. The European journal of neuroscience 20051001
A novel mechanism of G protein-dependent phosphorylation of vasodilator-stimulated phosphoprotein. The Journal of biological chemistry 20050923
Identical phenotypes of CatSper1 and CatSper2 null sperm. The Journal of biological chemistry 20050916
Changes in integrin expression during adipocyte differentiation. Cell metabolism 20050901
The FLT3 internal tandem duplication mutation prevents apoptosis in interleukin-3-deprived BaF3 cells due to protein kinase A and ribosomal S6 kinase 1-mediated BAD phosphorylation at serine 112. Cancer research 20050815
Role of upstream stimulatory factor phosphorylation in the regulation of the prostaglandin G/H synthase-2 promoter in granulosa cells. The Journal of biological chemistry 20050812
Differential expression of genes coding for EGF-like factors and ADAMTS1 following gonadotropin stimulation in normal and transformed human granulosa cells. Biochemical and biophysical research communications 20050805
Dynamic activation of cystic fibrosis transmembrane conductance regulator by type 3 and type 4D phosphodiesterase inhibitors. The Journal of pharmacology and experimental therapeutics 20050801
Progesterone inhibits gallbladder motility through multiple signaling pathways. Steroids 20050801
Activation of NMDA receptors induces protein kinase A-mediated phosphorylation and degradation of matrin 3. Blocking these effects prevents NMDA-induced neuronal death. Journal of neurochemistry 20050801
PACAP protects neuronal differentiated PC12 cells against the neurotoxicity induced by a mitochondrial complex I inhibitor, rotenone. FEBS letters 20050718
Characterization of cAMP-dependent proteolysis of GATA-6. Biochemical and biophysical research communications 20050715
Prostaglandins E1 and E2 inhibit lipopolysaccharide-induced interleukin-18 production in monocytes. European journal of pharmacology 20050711
Luteinizing hormone-induced extracellular-signal regulated kinase activation differently modulates progesterone and androstenedione production in bovine theca cells. Endocrinology 20050701
Urocortin stimulates tyrosine hydroxylase activity via the cAMP/protein kinase a pathway in rat Pheochromocytoma PC12 cells. Neuroscience letters 20050701
Enhancement of NMDA receptor phosphorylation of the spinal dorsal horn and nucleus gracilis neurons in neuropathic rats. Pain 20050701
Stimulation of catecholamine biosynthesis via the PKC pathway by prolactin-releasing peptide in PC12 rat pheochromocytoma cells. The Journal of endocrinology 20050701
Expression of TNFalpha and its receptors R1 and R2 in human alveolar epithelial cells exposed to organic dust and the effects of 8-bromo-cAMP and protein kinase A modulation. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050701
Vasoactive intestinal peptide (VIP) induces c-fos expression in LNCaP prostate cancer cells through a mechanism that involves Ca2+ signalling. Implications in angiogenesis and neuroendocrine differentiation. Biochimica et biophysica acta 20050630
Role of dual-site phospholamban phosphorylation in intermittent hypoxia-induced cardioprotection against ischemia-reperfusion injury. American journal of physiology. Heart and circulatory physiology 20050601
PI 3-kinase, protein kinase C, and protein kinase A are involved in the trigger phase of beta1-adrenergic preconditioning. Cardiovascular research 20050601
Tissue inhibitor of metalloproteinase-2 promotes neuronal differentiation by acting as an anti-mitogenic signal. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050518
Trapidil inhibits platelet-derived growth factor-induced migration via protein kinase A and RhoA/Rho-associated kinase in rat vascular smooth muscle cells. European journal of pharmacology 20050516
The cytosolic phospholipase A2 pathway, a safeguard of beta2-adrenergic cardiac effects in rat. The Journal of biological chemistry 20050513
Bidirectional regulation of AQP2 trafficking and recycling: involvement of AQP2-S256 phosphorylation. American journal of physiology. Renal physiology 20050501
Action of aluminum on high voltage-dependent calcium current and its modulation by ginkgolide B. Acta pharmacologica Sinica 20050501
Induction of leukemia cell apoptosis by cheliensisin A involves down-regulation of Bcl-2 expression. Acta pharmacologica Sinica 20050501
Signaling pathways in the biphasic effect of ANG II on Na+/H+ exchanger in T84 cells. The Journal of membrane biology 20050501
cAMP-mediated mechanisms for pain sensitization during opioid withdrawal. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050413
Virtual docking approaches to protein kinase B inhibition. Journal of medicinal chemistry 20050407
Ligand activated relaxin receptor increases the transcription of IGFBP-1 and prolactin in human decidual and endometrial stromal cells. Molecular human reproduction 20050401
H-89, a non-specific inhibitor of protein kinase A, promotes post-ischemic cardiac contractile recovery and reduces infarct size. Journal of cardiovascular pharmacology 20050401
Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway. European journal of endocrinology 20050401
Expression and regulation of murine macrophage angiopoietin-2. Cellular immunology 20050401
Induction of delta-opioid receptor function in the midbrain after chronic morphine treatment. The Journal of neuroscience : the official journal of the Society for Neuroscience 20050323
Activation of apical CFTR and basolateral Ca(2+)-activated K+ channels by tetramethylpyrazine in Caco-2 cell line. European journal of pharmacology 20050314
p38 mitogen-activated protein kinase downregulates endothelial progenitor cells. Circulation 20050308
cAMP and protein kinase A contribute to the downregulation of spinal glutamate transporters after chronic morphine. Neuroscience letters 20050307
Corticotropin-releasing hormone-mediated induction of intracellular signaling pathways and brain-derived neurotrophic factor expression is inhibited by the activation of the endocannabinoid system. Endocrinology 20050301
CB(1) cannabinoid receptor stimulation modulates transient receptor potential vanilloid receptor 1 activities in calcium influx and substance P Release in cultured rat dorsal root ganglion cells. Journal of pharmacological sciences 20050301
Hypotonic shock mediation by p38 MAPK, JNK, PKC, FAK, OSR1 and SPAK in osmosensing chloride secreting cells of killifish opercular epithelium. The Journal of experimental biology 20050301
Glucose stimulates the expression and activities of nitric oxide synthases in incubated rat islets: an effect counteracted by GLP-1 through the cyclic AMP/PKA pathway. Cell and tissue research 20050201
Posttraining intrahippocampal infusion of a protein kinase AII inhibitor impairs spatial memory retention in rats. Journal of neuroscience research 20050201
Inhibition of ATP-induced calcium influx in HT4 cells by glucocorticoids: involvement of protein kinase A. Acta pharmacologica Sinica 20050201
Differential effects of forskolin on tyrosine hydroxylase gene transcription in identified brainstem catecholaminergic neuronal subtypes in organotypic culture. The European journal of neuroscience 20050201
[Mechanisms of antidepressants and serotonin (5-HT)-induced glial cell line-derived neurotrophic factor (GDNF) releases in rat C6 gliobrastoma cells]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20050201
Cyclic AMP-protein kinase a and protein kinase C mediate in vitro T activation of brain tyrosine hydroxylase in the female catfish Heteropneustes fossilis. Journal of neuroendocrinology 20050201
Intracellular localization and trafficking of fluorescein-labeled cisplatin in human ovarian carcinoma cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20050115
Regulation of thrombomodulin expression in human vascular smooth muscle cells by COX-2-derived prostaglandins. Circulation research 20050107
Serine 68 phosphorylation of phospholemman: acute isoform-specific activation of cardiac Na/K ATPase. Cardiovascular research 20050101
Egr-1 negatively regulates expression of the sodium-calcium exchanger-1 in cardiomyocytes in vitro and in vivo. Cardiovascular research 20050101
Secretion of ATP from Schwann cells in response to uridine triphosphate. The European journal of neuroscience 20050101
Increase of delayed rectifier potassium currents in large aspiny neurons in the neostriatum following transient forebrain ischemia. Neuroscience 20050101
Leptin secretion and protein kinase A activity. Physiological research 20050101
[Reproductive hormones in the control of Th1/Th2 cytokine balance]. Izvestiia Akademii nauk. Seriia biologicheskaia 20050101
Differential roles of mGlu8 receptors in the regulation of glutamate and gamma-aminobutyric acid release at periaqueductal grey level. Neuropharmacology 20050101
Protein kinases mediate increment of the phosphorylation of cyclic AMP-responsive element binding protein in spinal cord of rats following capsaicin injection. Molecular pain 20050101
Metabolic arrest and its regulation in anoxic eel hepatocytes. Physiological and biochemical zoology : PBZ 20050101
Adrenomedullin induces matrix metalloproteinase-2 activity in rat aortic adventitial fibroblasts. Biochemical and biophysical research communications 20041203
Parathyroid hormone-related protein regulates apoptosis in lung cancer cells through protein kinase A. American journal of physiology. Cell physiology 20041201
Regulation of cyclin-dependent kinase 5 and calcium/calmodulin-dependent protein kinase II by phosphatidylinositol-linked dopamine receptor in rat brain. Molecular pharmacology 20041201
Effect of phosphodiesterase 4 inhibitors on NFAT-dependent cyclooxygenase-2 expression in human T lymphocytes. Cellular signalling 20041201
Irsogladine, an anti-ulcer drug, suppresses superoxide production by inhibiting phosphodiesterase type 4 in human neutrophils. Life sciences 20041119
Acute regulation of OAT3-mediated estrone sulfate transport in isolated rabbit renal proximal tubules. American journal of physiology. Renal physiology 20041101
Dietary K intake regulates the response of apical K channels to adenosine in the thick ascending limb. American journal of physiology. Renal physiology 20041101
Calcitonin gene-related peptide receptor activation produces PKA- and PKC-dependent mechanical hyperalgesia and central sensitization. Journal of neurophysiology 20041101
Phenylephrine induces activation of CREB in adult rat cardiac myocytes through MSK1 and PKA signaling pathways. Journal of molecular and cellular cardiology 20041101
Internalization of the human CRF receptor 1 is independent of classical phosphorylation sites and of beta-arrestin 1 recruitment. European journal of biochemistry 20041101
Human adipose angiotensinogen gene expression and secretion are stimulated by cyclic AMP via increased DNA cyclic AMP responsive element binding activity. Endocrine 20041101
Src tyrosine kinase regulates CYP17 expression and androstenedione secretion in theca-enriched mouse ovarian cells. Endocrine 20041101
Protein kinase A mediates microglial activation induced by plasminogen and gangliosides. Experimental & molecular medicine 20041031
Stimulation of Xenopus P2Y1 receptor activates CFTR in A6 cells. Pflugers Archiv : European journal of physiology 20041001
Nitric oxide-dependent beta2-adrenergic dilatation of rat aorta is mediated through activation of both protein kinase A and Akt. British journal of pharmacology 20041001
Motility of a biflagellate sperm: waveform analysis and cyclic nucleotide activation. Cell motility and the cytoskeleton 20041001
Ischemic preconditioning attenuates calpain-mediated degradation of structural proteins through a protein kinase A-dependent mechanism. Cardiovascular research 20041001
Regulation of myocardial heat shock protein 70 gene expression following exercise. Journal of molecular and cellular cardiology 20041001
Progesterone secretion by luteinizing human granulosa cells: a possible cAMP-dependent but PKA-independent mechanism involved in its regulation. The Journal of endocrinology 20041001
Endothelins negatively regulate glial glutamate transporter expression. Brain pathology (Zurich, Switzerland) 20041001
Nuclear receptor LXRalpha is involved in cAMP-mediated human renin gene expression. Molecular and cellular endocrinology 20040930
Autocrine regulation of steroidogenic function of Leydig cells by transforming growth factor-alpha. Molecular and cellular endocrinology 20040930
Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. The Journal of neuroscience : the official journal of the Society for Neuroscience 20040922
Facilitation of noradrenaline release by activation of adenosine A(2A) receptors triggers both phospholipase C and adenylate cyclase pathways in rat tail artery. Cardiovascular research 20040901
Dopamine D2-like antagonists induce chromatin remodeling in striatal neurons through cyclic AMP-protein kinase A and NMDA receptor signaling. Journal of neurochemistry 20040901
Basic calcium phosphate crystals activate p44/42 MAPK signal transduction pathway via protein kinase Cmicro in human fibroblasts. The Journal of biological chemistry 20040820
Activation of protein kinase C antagonizes the opioid inhibition of calcium current in rat spinal dorsal horn neurons. Brain research 20040813
Induction of orphan nuclear receptor Nur77 gene expression and its role in cadmium-induced apoptosis in lung. Carcinogenesis 20040801
Mechanism of cicaprost-induced desensitization in rat pulmonary artery smooth muscle cells involves a PKA-mediated inhibition of adenylyl cyclase. American journal of physiology. Lung cellular and molecular physiology 20040801
Hepatocyte growth factor promotes cell proliferation and inhibits progesterone secretion via PKA and MAPK pathways in a human granulosa cell line. Molecular reproduction and development 20040701
Histamine enhances cytotrophoblast invasion by inducing intracellular calcium transients through the histamine type-1 receptor. Molecular reproduction and development 20040701
Endothelin 1 and 3 enhance neuronal nitric oxide synthase activity through ETB receptors involving multiple signaling pathways in the rat anterior hypothalamus. Peptides 20040701
Neurotensin negatively modulates Akt activity in neurotensin receptor-1-transfected AV12 cells. Journal of cellular biochemistry 20040601
IFN-gamma activates cAMP/PKA/CREB signaling pathway in murine peritoneal macrophages. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20040601
Adenovirus-mediated delivery and expression of a cAMP-dependent protein kinase inhibitor gene to BEAS-2B epithelial cells abolishes the anti-inflammatory effects of rolipram, salbutamol, and prostaglandin E2: a comparison with H-89. The Journal of pharmacology and experimental therapeutics 20040501
Synergistic induction of the nicotinamide adenine dinucleotide-linked 15-hydroxyprostaglandin dehydrogenase by an androgen and interleukin-6 or forskolin in human prostate cancer cells. Endocrinology 20040501
Possible involvement of p38 MAP kinase in prostaglandin E1-induced ALP activity in osteoblast-like cells. Prostaglandins, leukotrienes, and essential fatty acids 20040501
Up-regulation of IL-4 production by the activated cAMP/cAMP-dependent protein kinase (protein kinase A) pathway in CD3/CD28-stimulated naive T cells. International immunology 20040501
Ergosterol elicits oxidative burst in tobacco cells via phospholipase A2 and protein kinase C signal pathway. Plant physiology and biochemistry : PPB 20040501
Quantal size of catecholamine release from rat chromaffin cells is regulated by tonic activity of protein kinase A. Neuroscience letters 20040429
Modulatory effect of endothelin-1 and -3 on neuronal norepinephrine release in the rat posterior hypothalamus. Regulatory peptides 20040415
cAMP-induced astrocytic differentiation of C6 glioma cells is mediated by autocrine interleukin-6. The Journal of biological chemistry 20040409
Action of EGF and PGE2 on basolateral organic anion uptake in rabbit proximal renal tubules and hOAT1 expressed in human kidney epithelial cells. American journal of physiology. Renal physiology 20040401
Identification in human airways smooth muscle cells of the prostanoid receptor and signalling pathway through which PGE2 inhibits the release of GM-CSF. British journal of pharmacology 20040401
Deletion mutant of FGFR4 induces onion-like membrane structures in the nucleus. Journal of cell science 20040401
Prostaglandin E1 induces vascular endothelial growth factor-1 in human adult cardiac myocytes but not in human adult cardiac fibroblasts via a cAMP-dependent mechanism. Journal of molecular and cellular cardiology 20040401
Heme oxygenase-1 gene expression in pericentral hepatocytes through beta1-adrenoceptor stimulation. Shock (Augusta, Ga.) 20040401
Induction of hyaluronic acid synthase 2 (HAS2) in human vascular smooth muscle cells by vasodilatory prostaglandins. Circulation research 20040319
Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter. The Journal of biological chemistry 20040312
Dioxin increases C/EBPbeta transcription by activating cAMP/protein kinase A. The Journal of biological chemistry 20040305
cAMP Dose-dependently prevents palmitate-induced apoptosis by both protein kinase A- and cAMP-guanine nucleotide exchange factor-dependent pathways in beta-cells. The Journal of biological chemistry 20040305
ATP-sensitive potassium channels mediate hyperosmotic stimulation of NKCC in slow-twitch muscle. American journal of physiology. Cell physiology 20040301
Protein kinase A-induced negative regulation of the corticotropin-releasing hormone R1alpha receptor-extracellularly regulated kinase signal transduction pathway: the critical role of Ser301 for signaling switch and selectivity. Molecular endocrinology (Baltimore, Md.) 20040301
General anesthetic octanol and related compounds activate wild-type and delF508 cystic fibrosis chloride channels. British journal of pharmacology 20040301
PACAP inhibits delayed rectifier potassium current via a cAMP/PKA transduction pathway: evidence for the involvement of I k in the anti-apoptotic action of PACAP. The European journal of neuroscience 20040301
Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol. The Journal of biological chemistry 20040227
Gs protein-coupled receptor agonists induce transactivation of the epidermal growth factor receptor in T84 cells: implications for epithelial secretory responses. The Journal of biological chemistry 20040220
Differential regulation of inducible nitric oxide synthase and cytokine gene expression by forskolin and dibutyryl-cAMP in lipopolysaccharide-stimulated murine BV2 microglial cells. Neuroscience letters 20040219
Potent ligand-independent estrogen receptor activation by 3,3'-diindolylmethane is mediated by cross talk between the protein kinase A and mitogen-activated protein kinase signaling pathways. Molecular endocrinology (Baltimore, Md.) 20040201
Protein kinase A and calcium/calmodulin-dependent protein kinase II regulate glycine and GABA release in auditory brain stem nuclei. Journal of neuroscience research 20040201
Histamine-induced inhibition of leukotriene biosynthesis in human neutrophils: involvement of the H2 receptor and cAMP. British journal of pharmacology 20040201
Activation of VPAC1 receptors by VIP and PACAP-27 in human bronchial epithelial cells induces CFTR-dependent chloride secretion. British journal of pharmacology 20040201
Calcitonin stimulates expression of the rat 25-hydroxyvitamin D3-24-hydroxylase (CYP24) promoter in HEK-293 cells expressing calcitonin receptor: identification of signaling pathways. Journal of molecular endocrinology 20040201
Inhibitory effects of group II mGluR-related drugs on memory performance in mice. Physiology & behavior 20040201
Alpha-keto-beta-methylvaleric acid increases the in vitro phosphorylation of intermediate filaments in cerebral cortex of young rats through the gabaergic system. Journal of the neurological sciences 20040115
Potent, selective and cell-mediated inhibition of human herpesvirus 6 at an early stage of viral replication by the non-nucleoside compound CMV423. Biochemical pharmacology 20040115
Inhibition of formyl-methionyl-leucyl-phenylalanine-stimulated respiratory burst in human neutrophils by adrenaline: inhibition of Phospholipase A2 activity but not p47phox phosphorylation and translocation. Biochemical pharmacology 20040101
Parathyroid hormone inhibits the expression of membrane-type matrix metalloproteinase-1 (MT1-MMP) in osteoblast-like MG-63 cells. Journal of bone and mineral metabolism 20040101
cAMP inhibits natriuretic peptide receptor-B activity and increases C-type natriuretic peptide in FRTL-5 rat thyroid cells. The Journal of endocrinology 20040101
Adrenocorticotropin induces heme oxygenase-1 expression in adrenal cells. The Journal of endocrinology 20040101
ACTH stimulates insulin secretion from MIN6 cells and primary mouse and human islets of Langerhans. The Journal of endocrinology 20040101
Phosphodiesterase 4 inhibition synergizes with relaxin signaling to promote decidualization of human endometrial stromal cells. The Journal of clinical endocrinology and metabolism 20040101
KF19514, a phosphodiesterase 4 and 1 inhibitor, inhibits TNF-alpha-induced GM-CSF production by a human bronchial epithelial cell line via inhibition of PDE4. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040101
Aquaporin-1 is recruited to the plasma membrane by hyperosmotic stimuli via a protein kinase A-dependent pathway in rat peritoneal mesothelial cells. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20040101
The effects of phosphoinositide/calcium- or cyclic AMP-mediated signal transduction pathway inhibitors on the activation of rat peritoneal macrophages by acetylated low-density lipoprotein. In vivo (Athens, Greece) 20040101
Desensitization of capsaicin-activated currents in the vanilloid receptor TRPV1 is decreased by the cyclic AMP-dependent protein kinase pathway. The Journal of biological chemistry 20031212
A bimodal modulation of the cAMP pathway is involved in the control of myogenic differentiation in l6 cells. The Journal of biological chemistry 20031205
Dual effects of pituitary adenylate cyclase-activating polypeptide and isoproterenol on lipid metabolism and signaling in primary rat adipocytes. Endocrinology 20031201
HIV-1 gp120 induces anergy in naive T lymphocytes through CD4-independent protein kinase-A-mediated signaling. Journal of leukocyte biology 20031201
Agonist-dependent internalization of the human melanocortin-4 receptors in human embryonic kidney 293 cells. The Journal of pharmacology and experimental therapeutics 20031201
Impact of nitric oxide on adrenomedullin- and proadrenomedullin N-terminal 20 peptide-induced cardiac responses: action by alone and combined administration. Peptides 20031201
Amylin gene expression mediated by cAMP/PKA and transcription factors HNF-1 and NFY. Molecular and cellular endocrinology 20031128
A forskolin derivative, colforsin daropate hydrochloride, inhibits rat mesangial cell mitogenesis via the cyclic AMP pathway. Pharmacology 20031101
Glucagon-like peptide-1 induces a cAMP-dependent increase of [Na+]i associated with insulin secretion in pancreatic beta-cells. American journal of physiology. Endocrinology and metabolism 20031101
Induction of cortical cataracts in cultured mouse lenses with H-89, an inhibitor of protein kinase A. Current eye research 20031101
Effects of eicosapentaenoic acid on cardiac SR Ca(2+)-release and ryanodine receptor function. Cardiovascular research 20031101
Nitric oxide enhances de novo formation of endothelial gap junctions. Cardiovascular research 20031101
Dopamine D1 receptors mediate CREB phosphorylation via phosphorylation of the NMDA receptor at Ser897-NR1. Journal of neurochemistry 20031101
Modulation of the reactive oxygen species (ROS) generation mediated by cyclic AMP-elevating agents or Interleukin 10 in granulocytes from type 2 diabetic patients (NIDDM): a PKA-independent phenomenon. Diabetes & metabolism 20031101
Effects of mechanical strain on the function of Gap junctions in osteocytes are mediated through the prostaglandin EP2 receptor. The Journal of biological chemistry 20031031
Prolactin-releasing peptide stimulates catecholamine release but not proliferation in rat pheochromocytoma PC12 cells. Neuroscience letters 20031016
Fructose modulates GLUT5 mRNA stability in differentiated Caco-2 cells: role of cAMP-signalling pathway and PABP (polyadenylated-binding protein)-interacting protein (Paip) 2. The Biochemical journal 20031001
Modulation of GABA release during morphine withdrawal in midbrain neurons in vitro. Neuropharmacology 20031001
Inositol derivatives modulate spontaneous transmitter release at the frog neuromuscular junction. Neuropharmacology 20031001
The roles of cyclic adenosine monophosphate- and cyclic guanosine monophosphate-dependent protein kinase pathways in hydrogen peroxide-induced contractility of microvascular lung pericytes. The Journal of trauma 20031001
Role of protein-tyrosine phosphatases on beta-adrenergic receptor mediated morphological differentiation of astrocytes. Journal of chemical neuroanatomy 20031001
Liquid-phase synthesis of a pegylated adenosine-oligoarginine conjugate, cell-permeable inhibitor of cAMP-dependent protein kinase. Bioorganic & medicinal chemistry letters 20030915
H89, an inhibitor of protein kinase A (PKA), stimulates Na+ transport by translocating an epithelial Na+ channel (ENaC) in fetal rat alveolar type II epithelium. Biochemical pharmacology 20030915
Protein kinase B is obligatory for follicle-stimulating hormone-induced granulosa cell differentiation. Endocrinology 20030901
Role of p38 MAPK in lupeol-induced B16 2F2 mouse melanoma cell differentiation. Journal of biochemistry 20030901
Phosphorylation of the vasodilator-stimulated phosphoprotein (VASP) by the anti-platelet drug, cilostazol, in platelets. Platelets 20030901
KCl potentiates forskolin-induced PC12 cell neurite outgrowth via protein kinase A and extracellular signal-regulated kinase signaling pathways. Neuroscience letters 20030814
Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras. The Journal of biological chemistry 20030808
Adjacent sequence controls the response polarity of nitric oxide-sensitive Sp factor binding sites. The Journal of biological chemistry 20030801
Involvement of tyrosine kinase and cAMP-dependent kinase cross-talk in the regulation of human sperm motility. Reproduction (Cambridge, England) 20030801
Parathyroid hormone (PTH) down-regulates PTH/PTH-related protein receptor gene expression in UMR-106 osteoblast-like cells via a 3',5'-cyclic adenosine monophosphate-dependent, protein kinase A-independent pathway. The Journal of endocrinology 20030801
Diverse regulation of atrial natriuretic peptide secretion by serotonin receptor subtypes. Cardiovascular research 20030801
Inhibition of pancreatic cancer cell growth and induction of apoptosis with novel therapies directed against protein kinase A. Surgery 20030801
Differential regulation of TNF-alpha, IL-6 and IL-10 in UVB-irradiated human keratinocytes via cyclic AMP/protein kinase A pathway. Cytokine 20030801
Changes in bad phosphorylation are correlated with BCR-induced apoptosis of WEHI-231 immature B cells. Biochimie 20030801
Striatal proenkephalin gene induction: coordinated regulation by cyclic AMP and calcium pathways. Brain research. Molecular brain research 20030723
Chromatin-dependent regulation of the MMTV promoter by cAMP signaling is mediated through distinct pathways. Experimental cell research 20030715
Rapid increase in endothelial nitric oxide production by bradykinin is mediated by protein kinase A signaling pathway. Biochemical and biophysical research communications 20030711
Inhibition of Abeta production and APP maturation by a specific PKA inhibitor. FEBS letters 20030710
Alpha-2 adrenoceptor mediating the facilitatory effect of norepinephrine on the glycine response in the spinal dorsal horn neuron of the rat. Life sciences 20030704
Evidence that the appressorial development in barley powdery mildew is controlled by MAP kinase activity in conjunction with the cAMP pathway. Fungal genetics and biology : FG & B 20030601
Urocortin-related peptides increase interleukin-6 output via cyclic adenosine 5'-monophosphate-dependent pathways in A7r5 aortic smooth muscle cells. Endocrinology 20030601
Subversion and utilization of the host cell cyclic adenosine 5'-monophosphate/protein kinase A pathway by Brucella during macrophage infection. Journal of immunology (Baltimore, Md. : 1950) 20030601
Lead-induced downregulation of soluble guanylate cyclase in isolated rat aortic segments mediated by reactive oxygen species and cyclooxygenase-2. Journal of the American Society of Nephrology : JASN 20030601
Reproductive hormones in the regulation of apoptosis of neutrophils. Biochemistry. Biokhimiia 20030601
Phosphorylation of the alpha4 subunit of human alpha4beta2 nicotinic receptors: role of cAMP-dependent protein kinase (PKA) and protein kinase C (PKC). Brain research. Molecular brain research 20030526
Regulatory mechanism of Cordyceps sinensis mycelium on mouse Leydig cell steroidogenesis. FEBS letters 20030522
Induction of adherent activity in mastocytoma P-815 cells by the cooperation of two prostaglandin E2 receptor subtypes, EP3 and EP4. The Journal of biological chemistry 20030516
Cyclic AMP-dependent protein kinase A and CREB are involved in neuregulin-induced synapse-specific expression of acetylcholine receptor gene. Biochemical and biophysical research communications 20030516
Synapse number and synaptic efficacy are regulated by presynaptic cAMP and protein kinase A. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030515
Synergistic effects of cystic fibrosis transmembrane conductance regulator and aquaporin-9 in the rat epididymis. Biology of reproduction 20030501
PLIF induces IL-10 production in monocytes: a calmodulin-p38 mitogen-activated protein kinase-dependent pathway. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501
Endometrial stromal cells undergoing decidualization down-regulate their properties to produce proinflammatory cytokines in response to interleukin-1 beta via reduced p38 mitogen-activated protein kinase phosphorylation. The Journal of clinical endocrinology and metabolism 20030501
5-HT decreases contractile and electrical activities in lymphatic vessels of the guinea-pig mesentery: role of 5-HT 7-receptors. British journal of pharmacology 20030501
Inhibition of ERK1/2 and CREB phosphorylation by caspase-dependent mechanism enhances apoptosis in a fibrosarcoma cell line treated with butyrate. Biochemical and biophysical research communications 20030411
Phosphorylation of protein tyrosine residues in fresh and cryopreserved stallion spermatozoa under capacitating conditions. Biology of reproduction 20030401
Regulation of melanocortin-4 receptor signaling: agonist-mediated desensitization and internalization. Endocrinology 20030401
Adrenocorticotropin induces mitogen-activated protein kinase phosphatase 1 in Y1 mouse adrenocortical tumor cells. Endocrinology 20030401
Insulin and glucagon regulation of glutathione S-transferase expression in primary cultured rat hepatocytes. The Journal of pharmacology and experimental therapeutics 20030401
Differential activation mechanisms of Erk-1/2 and p70(S6K) by glucose in pancreatic beta-cells. Diabetes 20030401
Exploring the regulation of the expression of ChAT and VAChT genes in NG108-15 cells: implication of PKA and PI3K signaling pathways. Neurochemical research 20030401
Alpha2-adrenoreceptor activation inhibits LTP and LTD in the basolateral amygdala: involvement of Gi/o-protein-mediated modulation of Ca2+-channels and inwardly rectifying K+-channels in LTD. The European journal of neuroscience 20030401
Expression of adrenomedullin and its receptor by chondrocyte phenotype cells. Biochemical and biophysical research communications 20030328
Transcriptional activation of the NF-kappaB p65 subunit by mitogen- and stress-activated protein kinase-1 (MSK1). The EMBO journal 20030317
Protein kinase A regulates GATA-3-dependent activation of IL-5 gene expression in Th2 cells. Journal of immunology (Baltimore, Md. : 1950) 20030315
Regulation of extracellular signal-regulated kinase by cannabinoids in hippocampus. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030315
Vasodilation by the calcium-mobilizing messenger cyclic ADP-ribose. The Journal of biological chemistry 20030314
Overexpression of copper/zinc superoxide dismutase in transgenic mice protects against neuronal cell death after transient focal ischemia by blocking activation of the Bad cell death signaling pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030301
Inhibition and facilitation by pimobendan, a calcium sensitizer, of catecholamine secretion from bovine adrenal chromaffin cells. Journal of pharmacological sciences 20030301
Fluoride-induced apoptosis in human epithelial lung cells (A549 cells): role of different G protein-linked signal systems. Human & experimental toxicology 20030301
Follicle-stimulating hormone activates extracellular signal-regulated kinase but not extracellular signal-regulated kinase kinase through a 100-kDa phosphotyrosine phosphatase. The Journal of biological chemistry 20030227
The phosphatidylinositol 3-kinase inhibitor LY294002 binds the estrogen receptor and inhibits 17beta-estradiol-induced transcriptional activity of an estrogen sensitive reporter gene. Molecular and cellular endocrinology 20030227
Norepinephrine induces slow calcium signalling in murine brown preadipocytes through the beta-adrenoceptor/cAMP/protein kinase A pathway. Cellular signalling 20030201
Enhancement of aquaporin-3 by vasoactive intestinal polypeptide in a human colonic epithelial cell line. Journal of gastroenterology and hepatology 20030201
Differential regulation of P-selectin expression by protein kinase A and protein kinase G in thrombin-stimulated human platelets. Thrombosis and haemostasis 20030201
Monocytic activation of protein tyrosine kinase, protein kinase A and protein kinase C induced by porins isolated from Salmonella enterica serovar Typhimurium. The Journal of infection 20030201
Phosphorylation of RGS14 by protein kinase A potentiates its activity toward G alpha i. Biochemistry 20030128
Normal function of HERG K+ channels expressed in HEK293 cells requires basal protein kinase B activity. FEBS letters 20030116
Propentofylline protects beta-amyloid protein-induced apoptosis in cultured rat hippocampal neurons. European journal of pharmacology 20030105
Rosiglitazone and retinoic acid induce uncoupling protein-1 (UCP-1) in a p38 mitogen-activated protein kinase-dependent manner in fetal primary brown adipocytes. The Journal of biological chemistry 20030103
Regulation of glutamatergic neurotransmission in the striatum by presynaptic adenylyl cyclase-dependent processes. Neurochemistry international 20030101
Cyclic AMP induces activation of extracellular signal-regulated kinases in HL-60 cells: role in cAMP-induced differentiation. Leukemia research 20030101
The expression of growth hormone-releasing hormone (GHRH) and its receptor splice variants in human breast cancer lines; the evaluation of signaling mechanisms in the stimulation of cell proliferation. Breast cancer research and treatment 20030101
Suppression of tumor necrosis factor-alpha by beta2-adrenoceptor activation: role of mitogen-activated protein kinases in renal mesangial cells. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030101
Adenosine suppresses the response of neurons to gaba in the superficial laminae of the rat spinal dorsal horn. Neuroscience 20030101
Reduction of MDR3 mRNA levels by forskolin in Chang liver cells. Anticancer research 20030101
Adrenomedullin inhibits pressure-induced mesangial MCP-1 expression through activation of protein kinase A. Journal of nephrology 20030101
Regulation of Na(+)-K(+)-2Cl- cotransporter activity in rat skeletal muscle and intestinal epithelial cells. Tsitologiia 20030101
Activation of protein kinase A induces neuronal differentiation of HiB5 hippocampal progenitor cells. Brain research. Molecular brain research 20021230
Lipolysis in the absence of hormone-sensitive lipase: evidence for a common mechanism regulating distinct lipases. Diabetes 20021201
cAMP-activated protein kinase-independent potentiation of insulin secretion by cAMP is impaired in SUR1 null islets. Diabetes 20021201
Involvement of 5-HT7 receptors in serotonergic effects on spike afterpotentials in presumed jaw-closing motoneurons of rats. Brain research 20021108
3',5'-cyclic adenosine monophosphate augments intracellular Ca2+ concentration and gonadotropin-releasing hormone (GnRH) release in immortalized GnRH neurons in an Na+ -dependent manner. Endocrinology 20021101
Regulation of growth hormone release in common carp pituitary cells by pituitary adenylate cyclase-activating polypeptide: signal transduction involves cAMP- and calcium-dependent mechanisms. Neuroendocrinology 20021101
Participation of various kinases in staurosporine induced apoptosis of RAW 264.7 cells. The Journal of pharmacy and pharmacology 20021101
Involvement of T-type calcium channels in the mechanism of action of 5-HT in rat glomerulosa cells: a novel signaling pathway for the 5-HT7 receptor. Endocrine research 20021101
A FRET-based assay platform for ultra-high density drug screening of protein kinases and phosphatases. Assay and drug development technologies 20021101
Orthovanadate decreases the leptin content in isolated mouse fat pads via proteasome activation. Archives of biochemistry and biophysics 20021015
Ovarian stanniocalcin is structurally unique in mammals and its production and release are regulated through the luteinizing hormone receptor. Endocrinology 20021001
Regulation of endothelin-A receptor sensitivity by cyclic adenosine monophosphate in rat hepatic stellate cells. Hepatology (Baltimore, Md.) 20021001
Tumor necrosis factor-alpha stimulates lipolysis in differentiated human adipocytes through activation of extracellular signal-related kinase and elevation of intracellular cAMP. Diabetes 20021001
Inhibition of human primary melanoma cell proliferation by histamine is enhanced by interleukin-6. European journal of clinical investigation 20021001
Inhibition of cGMP-dependent protein kinases potently decreases neutrophil spontaneous apoptosis. Biochemical and biophysical research communications 20020927
Cyclic AMP-mediated modulation of epileptiform afterdischarge generation in rat hippocampal slices. Brain research 20020913
MAP kinase stimulation by cAMP does not require RAP1 but SRC family kinases. The Journal of biological chemistry 20020906
Protein kinase mediated upregulation of endothelin A, endothelin B and 5-hydroxytryptamine 1B/1D receptors during organ culture in rat basilar artery. British journal of pharmacology 20020901
Parathyroid hormone-related peptide is a naturally occurring, protein kinase A-dependent angiogenesis inhibitor. Nature medicine 20020901
Adrenomedullin inhibits doxorubicin-induced cultured rat cardiac myocyte apoptosis via a cAMP-dependent mechanism. Endocrinology 20020901
Different signal transduction pathways are involved during human sperm capacitation induced by biological and pharmacological agents. Molecular human reproduction 20020901
Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neurons. Journal of neurophysiology 20020901
Ketoconazole suppresses interleukin-4 plus anti-CD40-induced IgE class switching in surface IgE negative B cells from patients with atopic dermatitis. The Journal of investigative dermatology 20020901
Dipyridamole inhibits in vitro renal fibroblast proliferation and collagen synthesis. The Journal of laboratory and clinical medicine 20020901
The relative relevance of phosphorylation of the Thr(17) residue of phospholamban is different at different levels of beta-adrenergic stimulation. Pflugers Archiv : European journal of physiology 20020901
Parathyroid hormone-related peptide regulation of chick tibial growth plate chondrocyte maturation requires protein kinase A. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20020901
Involvement of type I protein kinase A in the differentiation of L6 myoblast in conjunction with phosphatidylinositol 3-kinase. Molecules and cells 20020831
Toward a PKB inhibitor: modification of a selective PKA inhibitor by rational design. Biochemistry 20020813
Protein engineering of protein kinase A catalytic subunits results in the acquisition of novel inhibitor sensitivity. The Journal of biological chemistry 20020809
Inhibition of protein kinases A and C demonstrates dual modes of response in human eosinophils stimulated with platelet-activating factor. The Journal of allergy and clinical immunology 20020801
Mechanisms of mitogenic and anti-apoptotic signaling by glucose-dependent insulinotropic polypeptide in beta(INS-1)-cells. The Journal of endocrinology 20020801
Depressed PKA activity contributes to impaired SERCA function and is linked to the pathogenesis of glucose-induced cardiomyopathy. Journal of molecular and cellular cardiology 20020801
Sphingosine-induced c-jun expression: differences between sphingosine- and C2-ceramide-mediated signaling pathways. FEBS letters 20020731
Modulation by PKA of the hyperpolarization-activated current (Ih) in cultured rat olfactory receptor neurons. The Journal of membrane biology 20020715
Role of angiotensin II-induced cAMP in mesangial TNF-alpha production. Cytokine 20020707
Methylmercury inhibits nitric oxide production mediated by Ca(2+) overload and protein kinase A activation. Toxicology 20020701
Regulation of CDPKs, including identification of PAL kinase, in biotically stressed cells of French bean. Plant molecular biology 20020701
Effects of protein kinase a activation on the responses of primate spinothalamic tract neurons to mechanical stimuli. Journal of neurophysiology 20020701
Ketoconazole suppresses prostaglandin E(2)-induced cyclooxygenase-2 expression in human epidermoid carcinoma A-431 cells. The Journal of investigative dermatology 20020701
Protein kinase A balances the growth factor-induced Ras/ERK signaling. FEBS letters 20020619
Endocrine disrupter bisphenol a induces orphan nuclear receptor Nur77 gene expression and steroidogenesis in mouse testicular Leydig cells. Endocrinology 20020601
Glucose uptake via SGLT-1 is stimulated by beta(2)-adrenoceptors in the ruminal epithelium of sheep. The Journal of nutrition 20020601
Protein kinase A regulates beta2 integrin avidity in neutrophils. Journal of leukocyte biology 20020601
Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling. FEBS letters 20020522
Calcium-independent and cAMP-dependent modulation of soluble guanylyl cyclase activity by G protein-coupled receptors in pituitary cells. The Journal of biological chemistry 20020510
Regulation of urea permeability in frog urinary bladder by prostaglandin E(2). Pflugers Archiv : European journal of physiology 20020501
Protein kinases mediate nitric oxide-induced apoptosis in the insect cell line IPLB-LdFB. Cellular and molecular life sciences : CMLS 20020501
Protein phosphatase 2A is involved in the regulation of protein kinase A signaling pathway during in vitro chondrogenesis. Experimental cell research 20020415
cAMP-dependent protein kinase and proliferation differ in normal and polycystic kidney epithelia. American journal of physiology. Cell physiology 20020401
Phosphorylation of the salivary Na(+)-K(+)-2Cl(-) cotransporter. American journal of physiology. Cell physiology 20020401
Beta-adrenergic regulation of amiloride-sensitive lung sodium channels. American journal of physiology. Lung cellular and molecular physiology 20020401
Up-regulation of tryptophan hydroxylase expression and serotonin synthesis by sertraline. Molecular pharmacology 20020401
Regulation of extracellular signal-regulated kinase cascades by alpha- and beta-isoforms of the human thromboxane A(2) receptor. Molecular pharmacology 20020401
Regulation of plasminogen activator inhibitor-1 secretion by urokinase and tissue plasminogen activator in rat epithelioid-type smooth muscle cells. British journal of haematology 20020401
Vector-averaged gravity regulates gene expression of receptor activator of NF-kappaB (RANK) ligand and osteoprotegerin in bone marrow stromal cells via cyclic AMP/protein kinase A pathway. Bone 20020401
[Experimental study of low dose arsenic trioxide in treatment of patients with acute promyelocytic leukemia]. Ai zheng = Aizheng = Chinese journal of cancer 20020401
Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation. The Journal of biological chemistry 20020315
Caffeine-stimulated GTH-II release involves Ca(2+) stores with novel properties. American journal of physiology. Cell physiology 20020301
PTH and DA regulate Na-K ATPase through divergent pathways. American journal of physiology. Renal physiology 20020301
N(omega)-nitro-L-arginine inhibits inducible HSP-70 via Ca(2+), PKC, and PKA in human intestinal epithelial T84 cells. American journal of physiology. Gastrointestinal and liver physiology 20020301
The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase. The Journal of pharmacology and experimental therapeutics 20020301
C(2)-ceramide influences the expression and insulin-mediated regulation of cyclic nucleotide phosphodiesterase 3B and lipolysis in 3T3-L1 adipocytes. Diabetes 20020301
NFAT regulates insulin gene promoter activity in response to synergistic pathways induced by glucose and glucagon-like peptide-1. Diabetes 20020301
Stimulatory effects of hyperprolactinemia on aldosterone secretion in ovariectomized rats. Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20020301
mAChRs in the grasshopper brain mediate excitation by activation of the AC/PKA and the PLC second-messenger pathways. Journal of neurophysiology 20020201
Reduced level of serine(16) phosphorylated phospholamban in the failing rat myocardium: a major contributor to reduced SERCA2 activity. Cardiovascular research 20020201
The aniracetam metabolite 2-pyrrolidinone induces a long-term enhancement in AMPA receptor responses via a CaMKII pathway. Brain research. Molecular brain research 20020131
Phosphorylation of glycogen synthase kinase-3 and stimulation of T-cell factor signaling following activation of EP2 and EP4 prostanoid receptors by prostaglandin E2. The Journal of biological chemistry 20020125
Phosphorylation of inositol 1,4,5-trisphosphate receptors in parotid acinar cells. A mechanism for the synergistic effects of cAMP on Ca2+ signaling. The Journal of biological chemistry 20020111
Mediation of hippocampal mossy fiber long-term potentiation by presynaptic Ih channels. Science (New York, N.Y.) 20020104
Regulation of transepithelial phosphate transport by PTH in chicken proximal tubule epithelium. American journal of physiology. Regulatory, integrative and comparative physiology 20020101
[Adenylyl cyclase pathway is involved in the regulation of intracellular calcium level regulation in brown preadipocytes]. Tsitologiia 20020101
Involvement of cAMP but not PKA in the increase of corticosterone secretion in rat zona fasciculata-reticularis cells by aging. Journal of cellular biochemistry 20020101
Streptozotocin induces lipolysis in rat adipocytes in vitro. Physiological research 20020101
Signal transduction in Entamoeba histolytica induced by interaction with fibronectin: presence and activation of phosphokinase A and its possible relation to invasiveness. Archives of medical research 20020101
Roles of the cytoskeleton and of protein phosphorylation events in the osmotic stress response in eel intestinal epithelium. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20020101
A very late activating antigen-alpha4 (CD49d) monoclonal antibody, BU49 induces phosphorylation of a cAMP response element-binding protein (CREB), resulting in induction of homotypic cell aggregation and enhancement of interleukin-8 (IL-8) production. Microbiology and immunology 20020101
Role of glial glutamate transporters in the facilitatory action of FK960 on hippocampal neurotransmission. Brain research. Molecular brain research 20011216
Natriuretic peptides like NO facilitate cardiac vagal neurotransmission and bradycardia via a cGMP pathway. American journal of physiology. Heart and circulatory physiology 20011201
Enhancement by histamine of vascular endothelial growth factor production in granulation tissue via H(2) receptors. British journal of pharmacology 20011201
Angiotensin II promotes the phosphorylation of cyclic AMP-responsive element binding protein (CREB) at Ser133 through an ERK1/2-dependent mechanism. Journal of neurochemistry 20011201
Anti-mycotics suppress interleukin-4 and interleukin-5 production in anti-CD3 plus anti-CD28-stimulated T cells from patients with atopic dermatitis. The Journal of investigative dermatology 20011201
Novel marine-derived halogen-containing gramine analogues induce vasorelaxation in isolated rat aorta. European journal of pharmacology 20011130
Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells. FEBS letters 20011123
Glucose and forskolin regulate IAPP gene expression through different signal transduction pathways. American journal of physiology. Endocrinology and metabolism 20011101
Controls of EGF-induced morphological transformation of human bronchial epithelial cells. Journal of cellular physiology 20011101
Effect of short-term cyclic stretch on sodium pump activity in aortic smooth muscle cells. American journal of physiology. Heart and circulatory physiology 20011101
Activation of beta(2)-adrenoceptor prevents shiga toxin 2-induced TNF-alpha gene transcription. Journal of the American Society of Nephrology : JASN 20011101
Regulation of human beta(1)-adrenergic receptors and their mRNA in neuroepithelioma SK-N-MC cells: effects of agonist, forskolin, and protein kinase A. Biochemical pharmacology 20011101
Adenylate cyclase/protein kinase A signaling pathway enhances angiogenesis through induction of vascular endothelial growth factor in vivo. Japanese journal of pharmacology 20011101
Mechanisms in fluoride-induced interleukin-8 synthesis in human lung epithelial cells. Toxicology 20011015
Estrogen stimulates brain-derived neurotrophic factor expression in embryonic mouse midbrain neurons through a membrane-mediated and calcium-dependent mechanism. Journal of neuroscience research 20011015
Role of Na(+)/H(+) exchanger during O(2) deprivation in mouse CA1 neurons. American journal of physiology. Cell physiology 20011001
Acceleration of oviductal transport of oocytes induced by estradiol in cycling rats is mediated by nongenomic stimulation of protein phosphorylation in the oviduct. Biology of reproduction 20011001
Dipyridamole inhibits TGF-beta-induced collagen gene expression in human peritoneal mesothelial cells. Kidney international 20011001
Anti-leptin receptor antibody mimics the stimulation of lipolysis induced by leptin in isolated mouse fat pads. Journal of lipid research 20011001
Antidepressant drug treatments induce glial cell line-derived neurotrophic factor (GDNF) synthesis and release in rat C6 glioblastoma cells. Journal of neurochemistry 20011001
Norepinephrine induces apoptosis in skin melanophores by attenuating cAMP-PKA signals via alpha2-adrenoceptors in the medaka, Oryzias latipes. Pigment cell research 20011001
Noradrenaline and alpha-adrenergic signaling induce the hsp70 gene promoter in mollusc immune cells. Journal of cell science 20011001
Increased and correlated nuclear factor-kappa B and Ku autoantigen activities are associated with development of multidrug resistance. Oncogene 20010920
Induction of osteoblast differentiation indexes by PTHrP in MG-63 cells involves multiple signaling pathways. American journal of physiology. Endocrinology and metabolism 20010901
Protein kinase A-dependent and -independent effects of isoproterenol in rat isolated mesenteric artery: interactions with levcromakalim. The Journal of pharmacology and experimental therapeutics 20010901
Age-dependent stimulation of Leydig cell steroidogenesis by interleukin-1 isoforms. Molecular and cellular endocrinology 20010901
Regulation of slowly activating potassium current (I(Ks)) by secretin in rat pancreatic acinar cells. The Journal of physiology 20010901
Nitric oxide-cGMP pathway facilitates acetylcholine release and bradycardia during vagal nerve stimulation in the guinea-pig in vitro. The Journal of physiology 20010901
The H89 cAMP-dependent protein kinase inhibitor blocks Plasmodium falciparum development in infected erythrocytes. European journal of biochemistry 20010901
Prostaglandin E(2) modulation of vascular endothelial growth factor production in murine macrophages. Prostaglandins, leukotrienes, and essential fatty acids 20010901
Induction of neurite outgrowth in PC12 cells by alpha -phenyl-N-tert-butylnitron through activation of protein kinase C and the Ras-extracellular signal-regulated kinase pathway. The Journal of biological chemistry 20010831
Ultraviolet B-induced phosphorylation of histone H3 at serine 28 is mediated by MSK1. The Journal of biological chemistry 20010831
Biphasic modulation of nociceptive processing by the cyclic AMP-protein kinase A signalling pathway in sheep spinal cord. Neuroscience letters 20010831
Adenosine 3',5'-cyclic monophosphate (cAMP)-dependent inhibition of IL-5 from human T lymphocytes is not mediated by the cAMP-dependent protein kinase A. Journal of immunology (Baltimore, Md. : 1950) 20010815
Phosphorylation of mitogen-activated protein kinase is inhibited by calcitonin in DU145 prostate cancer cells. Cancer research 20010815
Role of cAMP-dependent protein kinase in the regulation of DNA repair. Cancer letters 20010810
Nuclear translocation of extracellular signal-regulated kinases in neuronal excitotoxicity. Neuroreport 20010808
Cardioprotective effect afforded by transient exposure to phosphodiesterase III inhibitors: the role of protein kinase A and p38 mitogen-activated protein kinase. Circulation 20010807
Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway. The Journal of biological chemistry 20010803
Polycystin-1 transforms the cAMP growth-responsive phenotype of M-1 cells. Kidney international 20010801
The inhibition of phosphatidylinositol-3-kinase induces neurite retraction and activates GSK3. Journal of neurochemistry 20010801
Diazepam increases the hypothalamic-pituitary-adrenocortical (HPA) axis activity by a cyclic AMP-dependent mechanism. British journal of pharmacology 20010801
Phosphorylation by PKA of a site unique to B-Raf kinase. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie 20010801
Distribution and function of JCV agnoprotein. Journal of neurovirology 20010801
Evidence for a novel thrombopoietin signalling event: activation of protein kinase A in human megakaryoblastic CMK cells. Cytokine 20010721
Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. The Journal of biological chemistry 20010706
Complex intracellular messenger pathways regulate one type of neuronal alpha-bungarotoxin-resistant nicotinic acetylcholine receptors expressed in insect neurosecretory cells (dorsal unpaired median neurons). Molecular pharmacology 20010701
EP1 and EP4 receptors mediate exocytosis evoked by prostaglandin E(2) in guinea-pig antral mucous cells. Experimental physiology 20010701
A new pathway for glucose-dependent insulinotropic polypeptide (GIP) receptor signaling: evidence for the involvement of phospholipase A2 in GIP-stimulated insulin secretion. The Journal of biological chemistry 20010629
Stimulation of astrocyte-enriched culture with C2 ceramide increases proenkephalin mRNA: involvement of cAMP-response element binding protein and mitogen activated protein kinases. Brain research 20010608
Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth. The Journal of biological chemistry 20010601
Expression and regulation of ClC-5 chloride channels: effects of antisense and oxidants. American journal of physiology. Cell physiology 20010601
cAMP-dependent fluid secretion in rat inner medullary collecting ducts. American journal of physiology. Renal physiology 20010601
Noradrenaline modulates oyster hemocyte phagocytosis via a beta-adrenergic receptor-cAMP signaling pathway. General and comparative endocrinology 20010601
Stretch-regulated exocytosis of discoidal vesicles in urinary bladder epithelium. Urology 20010601
Modulation of thapsigargin-induced calcium mobilisation by cyclic AMP-elevating agents in human lymphocytes is insensitive to the action of the protein kinase A inhibitor H-89. Cellular signalling 20010601
Thromboxane A(2) receptor mediated activation of the mitogen activated protein kinase cascades in human uterine smooth muscle cells. Biochimica et biophysica acta 20010528
Glucagon-like peptide-1 causes pancreatic duodenal homeobox-1 protein translocation from the cytoplasm to the nucleus of pancreatic beta-cells by a cyclic adenosine monophosphate/protein kinase A-dependent mechanism. Endocrinology 20010501
Analysis of the signal pathways involved in the regulation of fatty acid synthase gene expression by insulin and somatotropin. Journal of animal science 20010501
Analysis of inhibition by H89 of UCP1 gene expression and thermogenesis indicates protein kinase A mediation of beta(3)-adrenergic signalling rather than beta(3)-adrenoceptor antagonism by H89. Biochimica et biophysica acta 20010423
Forskolin inhibits expression of inducible nitric oxide synthase mRNA via inhibiting the mitogen activated protein kinase in C6 cells. Brain research. Molecular brain research 20010418
Inhibition of Kv1.3 channels by H-89 (N--[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide) independent of protein kinase A. Biochemical pharmacology 20010415
GRK3 mediates desensitization of CRF1 receptors: a potential mechanism regulating stress adaptation. American journal of physiology. Regulatory, integrative and comparative physiology 20010401
Alternatively spliced isoform of apical Na(+)-K(+)-Cl(-) cotransporter gene encodes a furosemide-sensitive Na(+)-Cl(-)cotransporter. American journal of physiology. Renal physiology 20010401
Regulation of acute cortisol synthesis by cAMP-dependent protein kinase and protein kinase C in a teleost species, the rainbow trout (Oncorhynchus mykiss). The Journal of endocrinology 20010401
Analysis of the role of the mitogen-activated protein kinase in mediating cyclic-adenosine 3',5'-monophosphate effects on prolactin promoter activity. Molecular endocrinology (Baltimore, Md.) 20010401
Direct autocrine inhibition and cAMP-dependent potentiation of single L-type Ca2+ channels in bovine chromaffin cells. The Journal of physiology 20010401
Modulation of rat erg1, erg2, erg3 and HERG K+ currents by thyrotropin-releasing hormone in anterior pituitary cells via the native signal cascade. The Journal of physiology 20010401
Herpesvirus quiescence in neuronal cells IV: virus activation induced by pituitary adenylate cyclase-activating polypeptide (PACAP) involves the protein kinase A pathway. Journal of neurovirology 20010401
Activation of serum- and glucocorticoid-induced protein kinase (Sgk) by cyclic AMP and insulin. The Journal of biological chemistry 20010323
Pituitary adenylate cyclase-activating polypeptide activates K(ATP) current in rat atrial myocytes. American journal of physiology. Heart and circulatory physiology 20010301
Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes. Journal of neurochemistry 20010301
Effects of melanocortin peptides on lipopolysaccharide/interferon-gamma-induced NF-kappaB DNA binding and nitric oxide production in macrophage-like RAW 264.7 cells: evidence for dual mechanisms of action. Biochemical pharmacology 20010301
Signaling mechanism underlying COX-2 induction by lysophosphatidylcholine. Biochemical and biophysical research communications 20010301
Role of Egr-1 in cAMP-dependent protein kinase regulation of the phenylethanolamine N-methyltransferase gene. Journal of neurochemistry 20010301
Forskolin modulation of desensitization at GABA(A) and glycine receptors is not mediated by cAMP-dependent protein kinase in isolated carp amacrine-like cells. Pflugers Archiv : European journal of physiology 20010301
Differential actions of PKA and PKC in the regulation of glutamate release by group III mGluRs in the entorhinal cortex. Journal of neurophysiology 20010201
Caffeine stores and dopamine differentially require Ca(2+) channels in goldfish somatotropes. American journal of physiology. Regulatory, integrative and comparative physiology 20010201
Purine and pyrimidine nucleotide-sensitive phospholipase A(2) in ampulla from frog semicircular canal. American journal of physiology. Regulatory, integrative and comparative physiology 20010201
Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit expression of Fas ligand in activated T lymphocytes by regulating c-Myc, NF-kappa B, NF-AT, and early growth factors 2/3. Journal of immunology (Baltimore, Md. : 1950) 20010115
Differential regulation of microglial NO production by protein kinase C inhibitors. Neurochemistry international 20010101
Protein tyrosine kinase-dependent regulation of adenylate cyclase and phosphatidylinositol 3-kinase activates the expression of glial fibrillary acidic protein upon induction of differentiation in rat c6 glioma. Cell biology international 20010101
Study of cytoskeletal changes induced by okadaic acid in BE(2)-M17 cells by means of a quantitative fluorimetric microplate assay. Toxicology in vitro : an international journal published in association with BIBRA 20010101
Effects of the PKA inhibitor H-89 on excitation-contraction coupling in skinned and intact skeletal muscle fibres. Journal of muscle research and cell motility 20010101
Differential mRNA expression of prostaglandin receptor subtypes in macrophage activation. Prostaglandins, leukotrienes, and essential fatty acids 20010101
Specificity and mechanism of action of some commonly used protein kinase inhibitors. The Biochemical journal 20001001
Use of an activation-specific probe to show that Rap1A and Rap1B display different sensitivities to activation by forskolin in rat1 cells. FEBS letters 20000721
Prostaglandin E2 and the protein kinase A pathway mediate arachidonic acid induction of c-fos in human prostate cancer cells. British journal of cancer 20000601
Norepinephrine induces vascular endothelial growth factor gene expression in brown adipocytes through a beta -adrenoreceptor/cAMP/protein kinase A pathway involving Src but independently of Erk1/2. The Journal of biological chemistry 20000505
Activation of transepithelial ion transport by secretin in human intestinal Caco-2 cells. The Japanese journal of physiology 20000401
Isoquinolinesulphonamide derivatives inhibit transcriptional elongation of human immunodeficiency virus type 1 RNA in a promyelocytic model of latency. Antiviral chemistry & chemotherapy 19990901
Dual intracellular signaling pathways mediated by the human cannabinoid CB1 receptor. European journal of pharmacology 19990625
Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. British journal of pharmacology 19990601
Regulation of glomerular mesangial cell proliferation in culture by adrenomedullin. European journal of pharmacology 19990507
Inhibitory effects of nitric oxide on the expression and activity of aromatase in human granulosa cells. Molecular human reproduction 19990501
Inhibition of forskolin-induced neurite outgrowth and protein phosphorylation by a newly synthesized selective inhibitor of cyclic AMP-dependent protein kinase, N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide (H-89), of PC12D pheochromocytoma cells. The Journal of biological chemistry 19900325
Direct effect of glucocorticoids on lipolysis in adipocytes. Molecular endocrinology (Baltimore, Md.)
20-HETE induces hyperglycemia through the cAMP/PKA-PhK-GP pathway. Molecular endocrinology (Baltimore, Md.)
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