Home Nitros N-Ethyl-n-(2-hydroxyethyl)nitrosamine

N-Ethyl-n-(2-hydroxyethyl)nitrosamine

CAS No.:
13147-25-6
Catalog Number:
AG000W9K
Molecular Formula:
C4H10N2O2
Molecular Weight:
118.1344
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$520
- +
5g
95%
In Stock USA
United States
$1378
- +
Product Description
Catalog Number:
AG000W9K
Chemical Name:
N-Ethyl-n-(2-hydroxyethyl)nitrosamine
CAS Number:
13147-25-6
Molecular Formula:
C4H10N2O2
Molecular Weight:
118.1344
MDL Number:
MFCD01727871
IUPAC Name:
N-ethyl-N-(2-hydroxyethyl)nitrous amide
InChI:
InChI=1S/C4H10N2O2/c1-2-6(5-8)3-4-7/h7H,2-4H2,1H3
InChI Key:
HNQBPUIXFDQDRJ-UHFFFAOYSA-N
SMILES:
OCCN(N=O)CC
Properties
Complexity:
67.1  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
118.074g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
118.136g/mol
Monoisotopic Mass:
118.074g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
52.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.1  
Literature
Title Journal
Phenobarbital mediates an epigenetic switch at the constitutive androstane receptor (CAR) target gene Cyp2b10 in the liver of B6C3F1 mice. PloS one 20110101
Chelation in metal intoxication. International journal of environmental research and public health 20100701
Potassium bromate enhances N-ethyl-N-hydroxyethylnitrosamine-induced kidney carcinogenesis only at high doses in Wistar rats: indication of the existence of an enhancement threshold. Toxicologic pathology 20091201
Etiology of bromate-induced cancer and possible modes of action-studies in Japan. Toxicology 20060417
Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity. Cancer letters 20021215
N-ethyl-N-hydroxyethylnitrosamine (EHEN)-induced renal and hepatocarcinogenesis in the tumor suppressor Tsc2 transgenic rat. Cancer letters 20021028
Down-regulation of von Hippel-Lindau protein in N-nitroso compound-induced rat non-clear cell renal tumors. Cancer letters 20020508
Microsome-mediated oxidation of N-nitrosodiethanolamine (NDELA), a bident carcinogen. Chemical research in toxicology 20020401
Strain variation in renal carcinogenesis by N-ethyl-N-hydroxyethylnitrosamine in F1 (Wistar-Fischer) rats. Cancer letters 20010920
Establishment and characterization of three new rat renal cell carcinoma cell lines from N-ethyl-N-hydroxyethylnitrosamine-induced basophilic cell tumors. Pathology international 20010201
Specific genomic alterations in rat renal cell carcinomas induced by N-ethyl-N-hydroxyethylnitrosamine. Toxicologic pathology 20010101
Effects of n-tritriacontane-16,18-dione, curcumin, chlorphyllin, dihydroguaiaretic acid, tannic acid and phytic acid on the initiation stage in a rat multi-organ carcinogenesis model. Cancer letters 19970226
Decreased connexin32 and a characteristic enzyme phenotype in clofibrate-induced preneoplastic lesions not shared with spontaneously occurring lesions in the rat liver. Carcinogenesis 19961101
Absence of ras family point mutations at codons 12, 13 and 61 in N-ethyl-N-hydroxyethylnitrosamine- or N-nitrosomorpholine-induced renal cell tumors in rats. Japanese journal of cancer research : Gann 19920901
Modifying effects of various chemicals on tumor development in a rat wide-spectrum organ carcinogenesis model. Japanese journal of cancer research : Gann 19920801
Modifying effects of the naturally occurring antioxidants gamma-oryzanol, phytic acid, tannic acid and n-tritriacontane-16, 18-dione in a rat wide-spectrum organ carcinogenesis model. Carcinogenesis 19911001
Synergistic effects of low-dose hepatocarcinogens in induction of glutathione S-transferase P-positive foci in the rat liver. Japanese journal of cancer research : Gann 19891001
Changes in gap junction protein (connexin 32) gene expression during rat liver carcinogenesis. Journal of cellular biochemistry 19891001
Reciprocal modifying effects of isomeric forms of aminophenol on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine. Carcinogenesis 19870901
Inhibition of neoplastic development in rat liver, kidney, oesophagus and forestomach by 4,4'-diaminodiphenylmethane administration. Carcinogenesis 19870501
Modifying effects of butylated hydroxyanisole, ethoxyquin and acetaminophen on induction of neoplastic lesions in rat liver and kidney initiated by N-ethyl-N-hydroxyethylnitrosamine. Carcinogenesis 19840401
Modification of chemical carcinogenesis by antioxidants. Princess Takamatsu symposia 19830101
Inhibitory effect of 4,4'-diaminodiphenylmethane on liver, kidney and bladder carcinogenesis in rats ingesting N-ethyl-N-hydroxyethylnitrosamine or N-butyl-N-(4-hydroxybutyl) nitros-amine. Carcinogenesis 19810101
Properties