Propanoic acid, 2-[4-[2-[(3,5-dimethylphenyl)amino]-2-oxoethyl]phenoxy]-2-methyl-
| Title | Journal |
|---|---|
| Non-cytotoxic radiosensitizers in brain radiotherapy: journey till the first decade of this millennium. | Current cancer drug targets 20120301 |
| Transport processes of radiopharmaceuticals and -modulators. | Radiation oncology (London, England) 20110101 |
| Dose-dense temozolomide regimen for the treatment of brain metastases from melanoma, breast cancer, or lung cancer not amenable to surgery or radiosurgery: a multicenter phase II study. | Annals of oncology : official journal of the European Society for Medical Oncology 20100301 |
| The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics. | Journal of neuro-oncology 20100101 |
| Whole brain radiotherapy with radiosensitizer for brain metastases. | Journal of experimental & clinical cancer research : CR 20090101 |
| Role of palliative radiotherapy in brain metastases. | Indian journal of palliative care 20090101 |
| Quality of life in brain metastases radiation trials: a literature review. | Current oncology (Toronto, Ont.) 20081001 |
| Reduction in hemoglobin-oxygen affinity results in the improvement of exercise capacity in mice with chronic heart failure. | Journal of the American College of Cardiology 20080826 |
| Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral. | Chemical communications (Cambridge, England) 20080307 |
| Neuropsychological testing and biomarkers in the management of brain metastases. | Radiation oncology (London, England) 20080101 |
| Improved survival, quality of life, and quality-adjusted survival in breast cancer patients treated with efaproxiral (Efaproxyn) plus whole-brain radiation therapy for brain metastases. | American journal of clinical oncology 20071201 |
| The effects of Efaproxyn (efaproxiral) on subcutaneous RIF-1 tumor oxygenation and enhancement of radiotherapy-mediated inhibition of tumor growth in mice. | Radiation research 20070801 |
| Using exposure-response and biomarkers to streamline early drug development. | Ernst Schering Research Foundation workshop 20070101 |
| Whole brain radiotherapy for brain metastases from breast cancer: estimation of survival using two stratification systems. | BMC cancer 20070101 |
| Current therapeutic approaches in patients with brain metastases. | Current treatment options in oncology 20061101 |
| Cerebral metastases--a therapeutic update. | Nature clinical practice. Neurology 20060801 |
| Efaproxiral red blood cell concentration predicts efficacy in patients with brain metastases. | British journal of cancer 20060619 |
| Role of efaproxiral in metastatic brain tumors. | Expert review of anticancer therapy 20060401 |
| Whole-brain radiotherapy with or without efaproxiral for the treatment of brain metastases: Determinants of response and its prognostic value for subsequent survival. | International journal of radiation oncology, biology, physics 20060315 |
| Mass spectrometric characterization of efaproxiral (RSR13) and its implementation into doping controls using liquid chromatography-atmospheric pressure ionization-tandem mass spectrometry. | Journal of mass spectrometry : JMS 20060301 |
| Efaproxiral (RSR13) plus oxygen breathing increases the therapeutic ratio of carboplatin in EMT6 mouse mammary tumors. | Experimental biology and medicine (Maywood, N.J.) 20060301 |
| Radiation sensitization with redox modulators: a promising approach. | International journal of radiation oncology, biology, physics 20060201 |
| New hope for old drug in patients with brain metastases. | The Lancet. Oncology 20060201 |
| Efaproxiral: should we hold our breath? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060101 |
| Phase III study of efaproxiral as an adjunct to whole-brain radiation therapy for brain metastases. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060101 |
| Integration of chemotherapy into current treatment strategies for brain metastases from solid tumors. | Radiation oncology (London, England) 20060101 |
| Blood doping by cobalt. Should we measure cobalt in athletes? | Journal of occupational medicine and toxicology (London, England) 20060101 |
| Efaproxiral: a radiation enhancer used in brain metastases from breast cancer. | The Annals of pharmacotherapy 20051201 |
| Phase II multicenter study of induction chemotherapy followed by concurrent efaproxiral (RSR13) and thoracic radiotherapy for patients with locally advanced non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050901 |
| Increased oxygenation of intracranial tumors by efaproxyn (efaproxiral), an allosteric hemoglobin modifier: In vivo EPR oximetry study. | International journal of radiation oncology, biology, physics 20050401 |
| Hit to Lead Success Stories--IBC Conference: Effective chemistry strategies for reducing attrition rates and speeding lead compounds into the pipeline. 31 January-1 February 2005, San Diego, CA, USA. | IDrugs : the investigational drugs journal 20050301 |
| R-state hemoglobin bound to heterotropic effectors: models of the DPG, IHP and RSR13 binding sites. | FEBS letters 20050131 |
| Efaproxiral: GSJ 61, JP 4, KDD 86, RS 4, RSR 13. | Drugs in R&D 20050101 |
| Effects of a pharmacologically-induced shift of hemoglobin-oxygen dissociation on myocardial energetics during ischemia in patients with coronary artery disease. | Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance 20050101 |
| Modeling of the response of ptO2 in rat brain to changes in physiological parameters. | Advances in experimental medicine and biology 20050101 |
| Novel radiosensitizers for tumors of the central nervous system. | Current opinion in investigational drugs (London, England : 2000) 20041201 |
| Effect of RSR13, an allosteric hemoglobin modifier, on oxygenation in murine tumors: an in vivo electron paramagnetic resonance oximetry and bold MRI study. | International journal of radiation oncology, biology, physics 20040701 |
| Efaproxiral: a novel radiation sensitiser. | Expert opinion on investigational drugs 20040501 |
| Effects of RSR13 and oxygen on the cytotoxicity of cisplatin and carboplatin to EMT6 mouse mammary tumor cells in vitro and in vivo. | Cancer chemotherapy and pharmacology 20040101 |
| Efaproxiral (Allos Therapeutics). | IDrugs : the investigational drugs journal 20030801 |
| RSR13 plus cranial radiation therapy in patients with brain metastases: comparison with the Radiation Therapy Oncology Group Recursive Partitioning Analysis Brain Metastases Database. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030615 |
| Allosteric modification of hemoglobin by RSR13 as a therapeutic strategy. | Advances in experimental medicine and biology 20030101 |
| The dose-dependent effect of RSR13, a synthetic allosteric modifier of hemoglobin, on physiological parameters and brain tissue oxygenation in rats. | Advances in experimental medicine and biology 20030101 |
| The effect of RSR13, a synthetic allosteric modifier of hemoglobin, on brain tissue pO2 (measured by EPR oximetry) following severe hemorrhagic shock in rats. | Advances in experimental medicine and biology 20030101 |
| [Blood doping and cardiovascular consequences]. | Presse medicale (Paris, France : 1983) 20021221 |
| Survival of patients with newly diagnosed glioblastoma multiforme treated with RSR13 and radiotherapy: results of a phase II new approaches to brain tumor therapy CNS consortium safety and efficacy study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020715 |
| Increasing P(50) does not improve DO(2CRIT) or systemic VO(2) in severe anemia. | American journal of physiology. Heart and circulatory physiology 20020701 |
| Pharmacological correction of hypothermic P(50) shift does not alter outcome from focal cerebral ischemia in rats. | American journal of physiology. Heart and circulatory physiology 20020501 |
| Synthesis and X-ray studies of chiral allosteric modifiers of hemoglobin. | Journal of medicinal chemistry 20020314 |
| Effects of enhanced oxygen release from hemoglobin by RSR13 in an acute renal failure model. | Kidney international 20011001 |
| Enhancement of tumor oxygenation and radiation response by the allosteric effector of hemoglobin, RSR13. | Radiation research 20010901 |
| High-resolution crystal structure of deoxy hemoglobin complexed with a potent allosteric effector. | Protein science : a publication of the Protein Society 20010501 |
| A phase I study of RSR13, a radiation-enhancing hemoglobin modifier: tolerance of repeated intravenous doses and correlation of pharmacokinetics with pharmacodynamics. | International journal of radiation oncology, biology, physics 20010315 |
| Allosteric modification of oxygen delivery by hemoglobin. | Anesthesia and analgesia 20010301 |
| RSR13, a potential athletic performance enhancement agent: detection in urine by gas chromatography/mass spectrometry. | Rapid communications in mass spectrometry : RCM 20010101 |