Home Other Building Blocks 2,2',4,4'-Tetrahydroxybenzophenone

2,2',4,4'-Tetrahydroxybenzophenone

CAS No.:
131-55-5
Catalog Number:
AG000VA6
Molecular Formula:
C13H10O5
Molecular Weight:
246.2155
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$13
- +
25g
98%
In Stock USA
United States
$32
- +
100g
98%
In Stock USA
United States
$82
- +
500g
98%
In Stock USA
United States
$300
- +
Product Description
Catalog Number:
AG000VA6
Chemical Name:
2,2',4,4'-Tetrahydroxybenzophenone
CAS Number:
131-55-5
Molecular Formula:
C13H10O5
Molecular Weight:
246.2155
MDL Number:
MFCD00002278
IUPAC Name:
bis(2,4-dihydroxyphenyl)methanone
InChI:
InChI=1S/C13H10O5/c14-7-1-3-9(11(16)5-7)13(18)10-4-2-8(15)6-12(10)17/h1-6,14-17H
InChI Key:
WXNRYSGJLQFHBR-UHFFFAOYSA-N
SMILES:
Oc1ccc(c(c1)O)C(=O)c1ccc(cc1O)O
EC Number:
205-028-9
UNII:
PRR8K3H9VN
NSC Number:
38556
Properties
Complexity:
278  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
246.053g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
246.218g/mol
Monoisotopic Mass:
246.053g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
98A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.4  
Literature
Title Journal
The effect of dermal benzophenone-2 administration on immune system activity, hypothalamic-pituitary-thyroid axis activity and hematological parameters in male Wistar rats. Toxicology 20180601
Identification and Molecular Interaction Studies of Thyroid Hormone Receptor Disruptors among Household Dust Contaminants. Chemical research in toxicology 20160815
Estimating Margin of Exposure to Thyroid Peroxidase Inhibitors Using High-Throughput in vitro Data, High-Throughput Exposure Modeling, and Physiologically Based Pharmacokinetic/Pharmacodynamic Modeling. Toxicological sciences : an official journal of the Society of Toxicology 20160501
Selectivity of natural, synthetic and environmental estrogens for zebrafish estrogen receptors. Toxicology and applied pharmacology 20141001
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway. Scientific reports 20140101
Pseudopolymorphism in hydroxybenzophenones: the dihydrate of 2,2',4,4'-tetrahydroxybenzophenone. Acta crystallographica. Section C, Crystal structure communications 20120401
Selective activation of zebrafish estrogen receptor subtypes by chemicals by using stable reporter gene assay developed in a zebrafish liver cell line. Toxicological sciences : an official journal of the Society of Toxicology 20120201
Ovariectomized mouse uterotrophic assay of 36 chemicals. The Journal of toxicological sciences 20120101
Effect of 2,2',4,4'-tetrahydroxybenzophenone (BP2) on steroidogenesis in testicular Leydig cells. Toxicology 20111009
Identification of classifiers for increase or decrease of thyroid peroxidase activity in the FTC-238/hTPO recombinant cell line. Environmental science & technology 20110915
Zebrafish eleutheroembryos provide a suitable vertebrate model for screening chemicals that impair thyroid hormone synthesis. Environmental science & technology 20110901
Comparison of relative binding affinities to fish and mammalian estrogen receptors: the regulatory implications. Toxicology letters 20100215
True photoallergy to sunscreens is rare despite popular belief. Dermatitis : contact, atopic, occupational, drug 20100101
Estrogenic activity of ternary UV filter mixtures in fish (Pimephales promelas) - an analysis with nonlinear isobolograms. Toxicology and applied pharmacology 20090101
Simultaneous trace determination of nine organic UV-absorbing compounds (UV filters) in environmental samples. Journal of chromatography. A 20080815
Pharmacokinetics and metabolism of benzophenone 2 in the rat. Toxicology 20080312
Cloud point extraction combined with micellar electrokinetic capillary chromatography determination of benzophenones in cosmetic matrix. Electrophoresis 20080201
Effects of the UV filter benzophenone-2 on reproduction in fish. Toxicology and applied pharmacology 20071215
In utero exposure to benzophenone-2 causes hypospadias through an estrogen receptor dependent mechanism. The Journal of urology 20071001
The ultraviolet filter benzophenone 2 interferes with the thyroid hormone axis in rats and is a potent in vitro inhibitor of human recombinant thyroid peroxidase. Endocrinology 20070601
Estrogenic activity of UV filter mixtures. Toxicology and applied pharmacology 20061115
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of molecular graphics & modelling 20061101
A dose-response study on the estrogenic activity of benzophenone-2 on various endpoints in the serum, pituitary and uterus of female rats. Archives of toxicology 20061001
In vitro effects of benzophenone-2 and octyl-methoxycinnamate on the production of interferon-gamma and interleukin-10 by murine splenocytes. Immunopharmacology and immunotoxicology 20060101
Effects of bisphenol-A (BPA), dibutylphtalate (DBP), benzophenone-2 (BP2), procymidone (Proc), and linurone (Lin) on fat tissue, a variety of hormones and metabolic parameters: a 3 months comparison with effects of estradiol (E2) in ovariectomized (ovx) rats. Toxicology 20050915
[Estrogenic activity of ultraviolet absorbers and the related compounds]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20050801
Estrogenic and antiandrogenic activities of 17 benzophenone derivatives used as UV stabilizers and sunscreens. Toxicology and applied pharmacology 20050215
Multi-organic endocrine disrupting activity of the UV screen benzophenone 2 (BP2) in ovariectomized adult rats after 5 days treatment. Toxicology 20041201
Pure estrogenic effect of benzophenone-2 (BP2) but not of bisphenol A (BPA) and dibutylphtalate (DBP) in uterus, vagina and bone. Toxicology 20041201
Effects of estradiol, benzophenone-2 and benzophenone-3 on the expression pattern of the estrogen receptors (ER) alpha and beta, the estrogen receptor-related receptor 1 (ERR1) and the aryl hydrocarbon receptor (AhR) in adult ovariectomized rats. Toxicology 20041201
Comparison of the reporter gene assay for ER-alpha antagonists with the immature rat uterotrophic assay of 10 chemicals. Toxicology letters 20030430
Immature rat uterotrophic assay of 18 chemicals and Hershberger assay of 30 chemicals. Toxicology 20030201
Estrogenic activity of phenolic additives determined by an in vitro yeast bioassay. Environmental health perspectives 20010201
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