Home Aminos Hexanoic acid, 3-(aminomethyl)-5-methyl-

Hexanoic acid, 3-(aminomethyl)-5-methyl-

CAS No.:
128013-69-4
Catalog Number:
AG000V3G
Molecular Formula:
C8H17NO2
Molecular Weight:
159.2261
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Purity
Availability
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Product Description
Catalog Number:
AG000V3G
Chemical Name:
Hexanoic acid, 3-(aminomethyl)-5-methyl-
CAS Number:
128013-69-4
Molecular Formula:
C8H17NO2
Molecular Weight:
159.2261
MDL Number:
MFCD00906155
IUPAC Name:
3-(aminomethyl)-5-methylhexanoic acid
InChI:
InChI=1S/C8H17NO2/c1-6(2)3-7(5-9)4-8(10)11/h6-7H,3-5,9H2,1-2H3,(H,10,11)
InChI Key:
AYXYPKUFHZROOJ-UHFFFAOYSA-N
SMILES:
NCC(CC(=O)O)CC(C)C
Properties
Complexity:
123  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
159.126g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
159.229g/mol
Monoisotopic Mass:
159.126g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
63.3A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.6  
Literature
Title Journal
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Pharmacokinetics and bioequivalence of a pregabalin 150-mg capsule in healthy Thai subjects. International journal of clinical pharmacology and therapeutics 20171001
Comparative effects of α2δ-1 ligands in mouse models of colonic hypersensitivity. World journal of gastroenterology 20160821
Comparison of oral absorption models for pregabalin: usefulness of transit compartment model. Drug design, development and therapy 20160101
Pregabalin alleviates the nitroglycerin-induced hyperalgesia in rats. Neuroscience 20150122
The double-edged sword: effects of pregabalin on experimentally induced sciatic nerve transection and crush injury in rats. The International journal of neuroscience 20150101
Paroxysmal itch caused by gain-of-function Nav1.7 mutation. Pain 20140901
Presynaptic inhibitory actions of pregabalin on excitatory transmission in superficial dorsal horn of mouse spinal cord: further characterization of presynaptic mechanisms. Neuroscience letters 20140113
Pregabalin alters nociceptive behavior and expression level of P2X3 receptor in the spinal dorsal horn in a rat model induced by chronic compression of the dorsal root ganglion. Anatomical record (Hoboken, N.J. : 2007) 20131201
Direct determination of pregabalin in human urine by nonaqueous CE-TOF-MS. Electrophoresis 20130501
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Pregabalin and topiramate regulate behavioural and brain gene transcription changes induced by spontaneous cannabinoid withdrawal in mice. Addiction biology 20130301
The potential of pregabalin in neurology, psychiatry and addiction: a qualitative overview. Current pharmaceutical design 20130101
Cost analysis of adding pregabalin or gabapentin to the management of community-treated patients with peripheral neuropathic pain. Journal of evaluation in clinical practice 20121201
Dosing pattern comparison between duloxetine and pregabalin among patients with diabetic peripheral neuropathic pain. Pain practice : the official journal of World Institute of Pain 20121101
Costs, work absence, and adherence in patients with partial onset seizures prescribed gabapentin or pregabalin. Epilepsy research 20121101
Development, validation and comparison of two microextraction techniques for the rapid and sensitive determination of pregabalin in urine and pharmaceutical formulations after ethyl chloroformate derivatization followed by gas chromatography-mass spectrometric analysis. Journal of pharmaceutical and biomedical analysis 20121101
Asymmetric time-dependent activation of right central amygdala neurones in rats with peripheral neuropathy and pregabalin modulation. The European journal of neuroscience 20121101
Perioperative pregabalin for acute and chronic pain after abdominal hysterectomy or myomectomy: a randomised controlled trial. European journal of anaesthesiology 20121101
Tolerability and use in co-administration of pregabalin in affective patients: a 6-month prospective naturalistic study. Expert opinion on drug safety 20121101
[Gait instability revealing a syndrome of inappropriate antidiuretic hormone secretion associated to pregabalin]. La Revue de medecine interne 20121101
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[Pregabalin for the reduction of opiate withdrawal symptoms]. Psychiatrische Praxis 20121001
The immunomodulatory effect of pregabalin on spleen cells in neuropathic mice. Anesthesia and analgesia 20121001
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Transcriptional upregulation of α2δ-1 elevates arterial smooth muscle cell voltage-dependent Ca2+ channel surface expression and cerebrovascular constriction in genetic hypertension. Hypertension (Dallas, Tex. : 1979) 20121001
Pregabalin treatment for peripheral neuropathic pain: a review of safety data from randomized controlled trials conducted in Japan and in the west. Drug safety 20121001
Topical pregabalin and diclofenac for the treatment of neuropathic orofacial pain in rats. Oral surgery, oral medicine, oral pathology and oral radiology 20121001
Pregabalin intoxication-induced encephalopathy with triphasic waves. Epilepsy & behavior : E&B 20121001
Effect of the anticonvulsant medications pregabalin and lamotrigine on urodynamic parameters in an animal model of neurogenic detrusor overactivity. Neurourology and urodynamics 20120901
Pregabalin- and topiramate-mediated regulation of cognitive and motor impulsivity in DBA/2 mice. British journal of pharmacology 20120901
Efficacy and safety of pregabalin for the treatment of chronic pruritus in Korea. The Journal of dermatology 20120901
The effect of pregabalin on sensorimotor gating in 'low' gating humans and mice. Neuropharmacology 20120901
Long-term maintenance of response across multiple fibromyalgia symptom domains in a randomized withdrawal study of pregabalin. The Clinical journal of pain 20120901
Pregabalin in clinical psychiatry and addiction: pros and cons. Expert opinion on investigational drugs 20120901
Opioids before and after initiation of pregabalin in patients with diabetic peripheral neuropathy. Current medical research and opinion 20120901
[A case of paclitaxel-induced peripheral neuropathy successfully treated with pregabalin]. Gan to kagaku ryoho. Cancer & chemotherapy 20120901
Systemic pregabalin attenuates sensorimotor responses and medullary glutamate release in inflammatory tooth pain model. Neuroscience 20120830
Pregabalin for chronic prostatitis. The Cochrane database of systematic reviews 20120815
Pharmacological characterization of lysophosphatidic acid-induced pain with clinically relevant neuropathic pain drugs. European journal of pain (London, England) 20120801
The prevention of chronic postsurgical pain using gabapentin and pregabalin: a combined systematic review and meta-analysis. Anesthesia and analgesia 20120801
Effects of pregabalin on the activity of glutamate transporter type 3. British journal of anaesthesia 20120801
Selectivity of action of pregabalin on Ca(2+) channels but not on fusion pore, exocytotic machinery, or mitochondria in chromaffin cells of the adrenal gland. The Journal of pharmacology and experimental therapeutics 20120801
α2δ ligands act as positive modulators of adult hippocampal neurogenesis and prevent depression-like behavior induced by chronic restraint stress. Molecular pharmacology 20120801
Elucidating the mechanism of action of pregabalin: α(2)δ as a therapeutic target in anxiety. CNS drugs 20120801
Chronic postsurgical pain: are we closer to understanding the puzzle? Anesthesia and analgesia 20120801
Pregabalin attenuates docetaxel-induced neuropathy in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20120801
Combination pharmacotherapy for the treatment of neuropathic pain in adults. The Cochrane database of systematic reviews 20120711
The efficacy of morphine, pregabalin, gabapentin, and duloxetine on mechanical allodynia is different from that on neuroma pain in the rat neuropathic pain model. Anesthesia and analgesia 20120701
Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia. The Journal of pharmacology and experimental therapeutics 20120701
Pregabalin induces hepatic hypoxia and increases endothelial cell proliferation in mice, a process inhibited by dietary vitamin E supplementation. Toxicological sciences : an official journal of the Society of Toxicology 20120701
Hemangiosarcoma in mice administered pregabalin: analysis of genotoxicity, tumor incidence, and tumor genetics. Toxicological sciences : an official journal of the Society of Toxicology 20120701
Mode of action associated with development of hemangiosarcoma in mice given pregabalin and assessment of human relevance. Toxicological sciences : an official journal of the Society of Toxicology 20120701
Key components of the mode of action for hemangiosarcoma induction in pregabalin-treated mice: evidence of increased bicarbonate, dysregulated erythropoiesis, macrophage activation, and increased angiogenic growth factors in mice but not in rats. Toxicological sciences : an official journal of the Society of Toxicology 20120701
Efficacy and safety of pregabalin in the treatment of alcohol and benzodiazepine dependence. Expert opinion on investigational drugs 20120701
Use of gabapentin and pregabalin for hand surgery patients. The Journal of hand surgery 20120701
Pregabalin for the treatment of fibromyalgia. Expert opinion on pharmacotherapy 20120701
Effects of anxiolytic treatment on potentiated startle during aversive image anticipation. Human psychopharmacology 20120701
Brainstem facilitations and descending serotonergic controls contribute to visceral nociception but not pregabalin analgesia in rats. Neuroscience letters 20120621
Modeling longitudinal daily seizure frequency data from pregabalin add-on treatment. Journal of clinical pharmacology 20120601
Reversible post-pregabalin peripheral edema in a spinal cord injury patient. Spinal cord 20120601
Costs and health resources utilization following switching to pregabalin in individuals with gabapentin-refractory neuropathic pain: a post hoc analysis. Pain practice : the official journal of World Institute of Pain 20120601
The adverse event profile of pregabalin across different disorders: a meta-analysis. European journal of clinical pharmacology 20120601
A 21-week open-label clinical trial of pregabalin as adjunctive therapy in partial seizures at multiple centers in Mexico (PREPS Mexico). Epilepsy research 20120601
Pain alleviation and patient-reported health outcomes following switching to pregabalin in individuals with gabapentin-refractory neuropathic pain in routine medical practice. Clinical drug investigation 20120601
Characterizing and understanding body weight patterns in patients treated with pregabalin. Current medical research and opinion 20120601
A cost-utility analysis of pregabalin versus duloxetine for the treatment of painful diabetic neuropathy. Journal of pain & palliative care pharmacotherapy 20120601
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[About the neuropathic component of back pain]. Ideggyogyaszati szemle 20120530
Interference of urinary amino acid analysis by pregabalin. Clinica chimica acta; international journal of clinical chemistry 20120518
Pregabalin for the discontinuation of long-term benzodiazepines use: an assessment of its effectiveness in daily clinical practice. European psychiatry : the journal of the Association of European Psychiatrists 20120501
A comparative efficacy of amitriptyline, gabapentin, and pregabalin in neuropathic cancer pain: a prospective randomized double-blind placebo-controlled study. The American journal of hospice & palliative care 20120501
Adjunctive therapy with pregabalin in generalized anxiety disorder patients with partial response to SSRI or SNRI treatment. International clinical psychopharmacology 20120501
Preoperative pregabalin administration significantly reduces postoperative opioid consumption and mechanical hyperalgesia after transperitoneal nephrectomy. British journal of anaesthesia 20120501
A randomized, placebo-controlled study of pregabalin for postoperative pain intensity after laparoscopic cholecystectomy. Journal of clinical anesthesia 20120501
Drug safety evaluation of pregabalin. Expert opinion on drug safety 20120501
Safety profile and tolerability of up to 1 year of pregabalin treatment in 3 open-label extension studies in patients with fibromyalgia. Clinical therapeutics 20120501
[A case of neurotoxicity reduced with pregabalin in R-CHOP chemotherapy for diffuse large B-cell lymphoma]. Gan to kagaku ryoho. Cancer & chemotherapy 20120501
Pilot study of duloxetine for cancer patients with neuropathic pain non-responsive to pregabalin. Anticancer research 20120501
A cost-effectiveness analysis of the effect of pregabalin versus usual care in the treatment of refractory neuropathic pain in routine medical practice in Spain. Pain medicine (Malden, Mass.) 20120501
Switching from long-term benzodiazepine therapy to pregabalin in patients with generalized anxiety disorder: a double-blind, placebo-controlled trial. Journal of psychopharmacology (Oxford, England) 20120401
Pregabalin: a treatment option for dystonia? Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20120401
Effects of pregabalin on smoking behavior, withdrawal symptoms, and cognitive performance in smokers. Psychopharmacology 20120401
Perioperative pregabalin for postoperative pain control and quality of life after major spinal surgery. Journal of neurosurgical anesthesiology 20120401
Non-estrogen conventional and phytochemical treatments for vasomotor symptoms: what needs to be known for practice. Climacteric : the journal of the International Menopause Society 20120401
Effect of pregabalin on sleep in patients with fibromyalgia and sleep maintenance disturbance: a randomized, placebo-controlled, 2-way crossover polysomnography study. Arthritis care & research 20120401
Non-opioid IV adjuvants in the perioperative period: pharmacological and clinical aspects of ketamine and gabapentinoids. Pharmacological research 20120401
Pregabalin increases slow-wave sleep and may improve attention in patients with partial epilepsy and insomnia. Epilepsy & behavior : E&B 20120401
Efficacy of pregabalin in a case of stiff-person syndrome: clinical and neurophysiological evidence. Journal of the neurological sciences 20120315
Health care costs in patients with painful diabetic peripheral neuropathy prescribed pregabalin or duloxetine. Pain practice : the official journal of World Institute of Pain 20120301
Pregabalin reduces alcohol drinking and relapse to alcohol seeking in the rat. Psychopharmacology 20120301
The analgesic effect of pregabalin in patients with chronic pain is reflected by changes in pharmaco-EEG spectral indices. British journal of clinical pharmacology 20120301
Pregabalin: dose-response relationship in generalized anxiety disorder. Pharmacopsychiatry 20120301
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Pregabalin in the treatment of refractory bipolar disorders. CNS neuroscience & therapeutics 20120301
Chronic pregabalin inhibits synaptic transmission between rat dorsal root ganglion and dorsal horn neurons in culture. Channels (Austin, Tex.) 20120301
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Anxiolytic-like effect of pregabalin on unconditioned fear in the rat: an autoradiographic brain perfusion mapping and functional connectivity study. NeuroImage 20120215
Determination of γ-hydroxybutyrate (GHB), β-hydroxybutyrate (BHB), pregabalin, 1,4-butane-diol (1,4BD) and γ-butyrolactone (GBL) in whole blood and urine samples by UPLC-MSMS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120215
Does early improvement predict endpoint response in patients with generalized anxiety disorder (GAD) treated with pregabalin or venlafaxine XR? European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20120201
Phenytoin, levetiracetam, and pregabalin in the acute management of refractory status epilepticus in patients with brain tumors. Neurocritical care 20120201
Interactions of pregabalin with gabapentin, levetiracetam, tiagabine and vigabatrin in the mouse maximal electroshock-induced seizure model: a type II isobolographic analysis. Epilepsy research 20120201
Cerebrospinal fluid neurotransmitter changes during the perioperative period in patients undergoing total knee replacement: a randomized trial. Anesthesia and analgesia 20120201
Randomised clinical trial: pregabalin attenuates the development of acid-induced oesophageal hypersensitivity in healthy volunteers - a placebo-controlled study. Alimentary pharmacology & therapeutics 20120201
Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. BET 3: can pregabalin effectively diminish acute herpetic pain and reduce the incidence of post-herpetic neuralgia? Emergency medicine journal : EMJ 20120201
[Medical treatment including pregabalin and radiation therapy provided remarkable relief for neuropathic pain by brachial plexus invasion in a patient with esophageal cancer]. Gan to kagaku ryoho. Cancer & chemotherapy 20120201
[Retrospective evaluation of pregabalin for cancer-related neuropathic pain]. Masui. The Japanese journal of anesthesiology 20120201
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Health care costs in patients with fibromyalgia on pregabalin vs. duloxetine. Pain practice : the official journal of World Institute of Pain 20120101
A double-blind randomized crossover study to evaluate the timing of pregabalin for third molar surgery under local anesthesia. Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons 20120101
Inferior alveolar nerve injury resulting from overextension of an endodontic sealer: non-surgical management using the GABA analogue pregabalin. International endodontic journal 20120101
Clinical characteristics, pharmacotherapy, and healthcare resource use among patients with fibromyalgia newly prescribed pregabalin or tricyclic antidepressants. Journal of medical economics 20120101
Clinical comorbidities, treatment patterns, and healthcare costs among patients with fibromyalgia newly prescribed pregabalin or duloxetine in usual care. Journal of medical economics 20120101
A cost-utility study of the use of pregabalin in treatment-refractory neuropathic pain. Journal of medical economics 20120101
Persistent genital arousal disorder: successful treatment with duloxetine and pregabalin in two cases. The journal of sexual medicine 20120101
Economic evaluation of duloxetine as a first-line treatment for painful diabetic peripheral neuropathy in Mexico. Journal of medical economics 20120101
Subjective, psychomotor, and physiological effects of pregabalin alone and in combination with oxycodone in healthy volunteers. Pharmacology, biochemistry, and behavior 20120101
A case of severe oral self-injurious Tourette's syndrome alleviated by pregabalin. General hospital psychiatry 20120101
Pregabalin beneficial effects on sleep quality or health-related quality of life are poorly correlated with reduction on pain intensity after an 8-week treatment course. Clinical neuropharmacology 20120101
Sensory pain qualities in neuropathic pain. The journal of pain : official journal of the American Pain Society 20120101
Delirium secondary to pregabalin. General hospital psychiatry 20120101
Costs of pregabalin or gabapentin for painful diabetic peripheral neuropathy. Journal of medical economics 20120101
The relationship between gabapentin and pregabalin and posttraumatic stress disorder in burned servicemembers. Journal of burn care & research : official publication of the American Burn Association 20120101
Efficacy and safety of pregabalin in the treatment of alcohol withdrawal syndrome: a randomized placebo-controlled trial. Alcohol and alcoholism (Oxford, Oxfordshire) 20120101
The effects of preemptive pregabalin on attenuation of stress response to endotracheal intubation and opioid-sparing effect in patients undergoing off-pump coronary artery bypass grafting. Annals of cardiac anaesthesia 20120101
Comparison of central versus peripheral delivery of pregabalin in neuropathic pain states. Molecular pain 20120101
Evaluation of the neurological safety of epidurally-administered pregabalin in rats. Korean journal of anesthesiology 20120101
The cost-effectiveness of pregabalin in the treatment of fibromyalgia: US perspective. Journal of medical economics 20120101
Cost-effectiveness analysis of pharmacologic treatment of fibromyalgia in Mexico. Reumatologia clinica 20120101
[Pregabalin--a drug with abuse potential?]. Archiv fur Kriminologie 20120101
Addition of pregabalin to multimodal analgesic therapy following ankle surgery: a randomized double-blind, placebo-controlled trial. Regional anesthesia and pain medicine 20120101
Oral pregabalin premedication for attenuation of haemodynamic pressor response of airway instrumentation during general anaesthesia: A dose response study. Indian journal of anaesthesia 20120101
Pain and pain behavior in burning mouth syndrome: a pain diary study. Journal of orofacial pain 20120101
Pregabalin and gabapentin for post-photorefractive keratectomy pain: a randomized controlled trial. European journal of ophthalmology 20120101
Muscle rigidity associated with pregabalin. Pain physician 20120101
The effects of pregabalin and the glial attenuator minocycline on the response to intradermal capsaicin in patients with unilateral sciatica. PloS one 20120101
Comparative study of clinical efficacy of amitriptyline and pregabalin in postherpetic neuralgia. Acta dermatovenerologica Croatica : ADC 20120101
A case of pregabalin intoxication. Psychiatrike = Psychiatriki 20120101
Pregabalin resolves refractory aparathyroid paroxysmal kinesigenic choreoathetosis. Clinical neuropharmacology 20120101
Pregabalin antinociception and its interaction with tramadol in acute model of pain. Pharmacological reports : PR 20120101
Synergistic interaction of pregabalin with the synthetic cannabinoid WIN 55,212-2 mesylate in the hot-plate test in mice: an isobolographic analysis. Pharmacological reports : PR 20120101
Heart failure assocated with pregabalin. Pain physician 20120101
Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial. PloS one 20120101
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A protocol for a systematic review for perioperative pregabalin use. Systematic reviews 20120101
An international, randomized, double-blind, placebo-controlled, phase III trial of pregabalin monotherapy in treatment of patients with fibromyalgia. The Journal of rheumatology 20111201
Perioperative administration of gabapentin 1,200 mg day-1 and pregabalin 300 mg day-1 for pain following lumbar laminectomy and discectomy: a randomised, double-blinded, placebo-controlled study. Singapore medical journal 20111201
An open-label, add-on study of pregabalin in patients with partial seizures: a multicenter trial in Greece. Seizure 20111101
Neoteric pharmacotherapeutic targets in fibromyalgia. Expert opinion on therapeutic targets 20111101
[Mechanisms of action of therapeutic agents in the treatment of chronic pain in the spinal cord]. Masui. The Japanese journal of anesthesiology 20111101
Efficacy and tolerability of pregabalin as preventive treatment for migraine: a 3-month follow-up study. The journal of headache and pain 20111001
[Pregabalin and gabapentin in multiple sclerosis: clinical experiences and therapeutic implications]. Der Nervenarzt 20111001
Effect of pregabalin on post-dural-puncture headache following spinal anesthesia and lumbar puncture. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20111001
Pregabalin modulation of spinal and brainstem visceral nociceptive processing. Pain 20111001
Randomised clinical trial: pregabalin attenuates experimental visceral pain through sub-cortical mechanisms in patients with painful chronic pancreatitis. Alimentary pharmacology & therapeutics 20111001
Pregabalin augmentation in treatment-resistant obsessive-compulsive disorder: a 16-week case series. Journal of clinical psychopharmacology 20111001
What is a fair comparison in head-to-head trials of antiepileptic drugs? The Lancet. Neurology 20111001
Efficacy and safety of pregabalin versus lamotrigine in patients with newly diagnosed partial seizures: a phase 3, double-blind, randomised, parallel-group trial. The Lancet. Neurology 20111001
Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis. Arthritis and rheumatism 20111001
[Oxycodone and pregabalin using transdermal fentanyl patch provided relief of symptoms for postherpetic neuropathic pain in a patient with non-small cell lung cancer]. Gan to kagaku ryoho. Cancer & chemotherapy 20111001
Pregabalin is a potent and selective ligand for α(2)δ-1 and α(2)δ-2 calcium channel subunits. European journal of pharmacology 20110930
An in vitro model for testing drugs to treat tinnitus. European journal of pharmacology 20110930
The impact of background antiepileptic drugs on the efficacy and safety of pregabalin in treating partial-onset seizures: a post hoc analysis of combined clinical trials. Epilepsy research 20110901
Synergistic antihypersensitive effects of pregabalin and tapentadol in a rat model of neuropathic pain. European journal of pharmacology 20110901
Retrospective chart review of duloxetine and pregabalin in the treatment of painful neuropathy. The International journal of neuroscience 20110901
Efficacy and safety of perioperative pregabalin for post-operative pain: a meta-analysis of randomized-controlled trials. Acta anaesthesiologica Scandinavica 20110901
Efficacy of pregabalin in preventing relapse in patients with generalized social anxiety disorder: results of a double-blind, placebo-controlled 26-week study. International clinical psychopharmacology 20110901
Medication dosing patterns associated with duloxetine and pregabalin among patients with fibromyalgia. Current medical research and opinion 20110901
Listening to Lyrica: contested illnesses and pharmaceutical determinism. Social science & medicine (1982) 20110901
Post hoc analysis of pregabalin vs. non-pregabalin treatment in patients with cancer-related neuropathic pain: better pain relief, sleep and physical health. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20110901
Review of current guidelines on the care of postherpetic neuralgia. Postgraduate medicine 20110901
A meta-analysis of the efficacy of pregabalin in the treatment of generalized anxiety disorder. Canadian journal of psychiatry. Revue canadienne de psychiatrie 20110901
High-resolution sonography of posttraumatic neuroma of the superficial radial nerve. Central European neurosurgery 20110801
Adjunctive pregabalin for uncontrolled partial-onset seizures: findings from a prospective audit. Acta neurologica Scandinavica 20110801
Anxiolytic-like activity of pregabalin in the Vogel conflict test in α2δ-1 (R217A) and α2δ-2 (R279A) mouse mutants. The Journal of pharmacology and experimental therapeutics 20110801
Effect of the α2δ ligand, pregabalin, on colonic sensory and motor functions in healthy adults. American journal of physiology. Gastrointestinal and liver physiology 20110801
Pregabalin reduces pain in patients with chronic pancreatitis in a randomized, controlled trial. Gastroenterology 20110801
Pregabalin assay in a patient with widespread neuropathic pain and late onset gluten intolerance. Pain medicine (Malden, Mass.) 20110801
Efficacy of pregabalin in acute postoperative pain: a meta-analysis. British journal of anaesthesia 20110801
[Abuse of pregabalin exists--but it's uncertain how often]. Lakartidningen 20110801
Pharmacotherapy of fibromyalgia. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110715
Population pharmacokinetics of pregabalin in healthy subjects and patients with post-herpetic neuralgia or diabetic peripheral neuropathy. British journal of clinical pharmacology 20110701
Efficacy of pregabalin in generalized social anxiety disorder: results of a double-blind, placebo-controlled, fixed-dose study. International clinical psychopharmacology 20110701
Attenuating effect of hydroalcoholic extract of Acorus calamus in vincristine-induced painful neuropathy in rats. Journal of natural medicines 20110701
Pregabalin augmentation in treatment-resistant obsessive-compulsive disorder. International clinical psychopharmacology 20110701
Amperometric measurement of glutamate release modulation by gabapentin and pregabalin in rat neocortical slices: role of voltage-sensitive Ca2+ α2δ-1 subunit. The Journal of pharmacology and experimental therapeutics 20110701
Effects of antiepileptic drugs on GABA release from rat and human neocortical synaptosomes. Naunyn-Schmiedeberg's archives of pharmacology 20110701
Pregabalin or placebo used adjunctively with levetiracetam in refractory partial-onset epilepsy: a post hoc efficacy and safety analysis in combined clinical trials. Current medical research and opinion 20110701
Pregabalin suppresses spinal neuronal hyperexcitability and visceral hypersensitivity in the absence of peripheral pathophysiology. Anesthesiology 20110701
Pregabalin-induced hepatotoxicity. European journal of gastroenterology & hepatology 20110701
Replacement of gabapentin with pregabalin in postherpetic neuralgia therapy. Pain medicine (Malden, Mass.) 20110701
Duloxetine, pregabalin, and duloxetine plus gabapentin for diabetic peripheral neuropathic pain management in patients with inadequate pain response to gabapentin: an open-label, randomized, noninferiority comparison. Mayo Clinic proceedings 20110701
Urine drug testing of chronic pain patients. IV. prevalence of gabapentin and pregabalin. Journal of analytical toxicology 20110701
Pregabalin in the treatment of posttraumatic stress disorder: a case report. Progress in neuro-psychopharmacology & biological psychiatry 20110601
Pregabalin in severe burn injury pain: a double-blind, randomised placebo-controlled trial. Pain 20110601
Pregabalin influences insula and amygdala activation during anticipation of emotional images. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110601
Pregabalin has an opioid-sparing effect in elderly patients after cardiac surgery: a randomized placebo-controlled trial. British journal of anaesthesia 20110601
Longitudinal monitoring of the safety of drugs by using a web-based system: the case of pregabalin. Pharmacoepidemiology and drug safety 20110601
Pregabalin-induced hepatotoxicity. The Annals of pharmacotherapy 20110601
Painful diabetic neuropathy--new choice of first-line therapy? Nature reviews. Endocrinology 20110531
[Clarification about pregabalin and the Norwegian Prescription Database]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110506
Modeling dropout from adverse event data: impact of dosing regimens across pregabalin trials in the treatment of generalized anxiety disorder. Journal of clinical pharmacology 20110501
Applying area-under-the-curve analysis to enhance interpretation of response profiles: an application to sleep quality scores in patients with fibromyalgia. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation 20110501
Safety and efficacy of pregabalin in patients with central post-stroke pain. Pain 20110501
Pregabalin-induced suicidal ideations. Pharmacopsychiatry 20110501
Is pregabalin ineffective in poststroke pain? Pain 20110501
Cost-effectiveness analysis of a new 8% capsaicin patch compared to existing therapies for postherpetic neuralgia. Current medical research and opinion 20110501
Effect of a single dose of pregabalin on post-operative pain and pre-operative anxiety in patients undergoing discectomy. Acta anaesthesiologica Scandinavica 20110501
[Neuropathic pain in oncology. Novel evidence for clinical practice]. Recenti progressi in medicina 20110501
Interaction between adalimumab with concurrent pregabalin and duloxetine administration in a psoriasis patient with diabetic peripheral neuropathy. Cutis 20110501
[To misunderstand about pregabalin abuse]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110408
Systematic review of the comparative effectiveness of antiepileptic drugs for fibromyalgia. The journal of pain : official journal of the American Pain Society 20110401
Medication adherence and healthcare costs among patients with diabetic peripheral neuropathic pain initiating duloxetine versus pregabalin. Current medical research and opinion 20110401
The adverse event profile of pregabalin: a systematic review and meta-analysis of randomized controlled trials. Epilepsia 20110401
Effects of pregabalin on heart rate variability in patients with painful diabetic neuropathy. Journal of clinical psychopharmacology 20110401
Efficacy of pregabalin in acute postoperative pain: a meta-analysis. British journal of anaesthesia 20110401
Possible heart failure associated with pregabalin use: case report. Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20110401
Fibromyalgia and sleep. Best practice & research. Clinical rheumatology 20110401
Pharmacotherapy of fibromyalgia. Best practice & research. Clinical rheumatology 20110401
Effective dose of peri-operative oral pregabalin as an adjunct to multimodal analgesic regimen in lumbar spinal fusion surgery. Spine 20110315
Dissociation of rewarding, anti-aversive and anti-nociceptive effects of different classes of anti-nociceptives in the rat. European journal of pain (London, England) 20110301
A case of unilateral burning mouth syndrome of neuropathic origin. Headache 20110301
Earlier discovery of pregabalin's dependence potential might have been possible. European journal of clinical pharmacology 20110301
Pregabalin suppresses calcium-mediated proteolysis and improves stroke outcome. Neurobiology of disease 20110301
Pregabalin modulation of neurotransmitter release is mediated by change in intrinsic activation/inactivation properties of ca(v)2.1 calcium channels. The Journal of pharmacology and experimental therapeutics 20110301
Impact of responder definition on the enriched enrollment randomized withdrawal trial design for establishing proof of concept in neuropathic pain. Pain 20110301
Pregabalin reduces post-operative pain after mastectomy: a double-blind, randomized, placebo-controlled study. Acta anaesthesiologica Scandinavica 20110301
Pregabalin and dexamethasone improves post-operative pain treatment after tonsillectomy. Acta anaesthesiologica Scandinavica 20110301
Intensive monitoring of pregabalin: results from an observational, Web-based, prospective cohort study in the Netherlands using patients as a source of information. Drug safety 20110301
Pregabalin as a neuroprotector after spinal cord injury in rats: biochemical analysis and effect on glial cells. Journal of Korean medical science 20110301
[The prescription registry and abuse of pregabalin]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110204
The anxiolytic effect of pregabalin in outpatients undergoing minor orthopaedic surgery. Journal of psychopharmacology (Oxford, England) 20110201
[Pregabalin and postoperative hyperalgesia. A review]. Schmerz (Berlin, Germany) 20110201
[Glossopharyngeal neuralgia after resection of a glossopharyngeal schwannoma]. Schmerz (Berlin, Germany) 20110201
Correlations between fibromyalgia symptom and function domains and patient global impression of change: a pooled analysis of three randomized, placebo-controlled trials of pregabalin. Pain medicine (Malden, Mass.) 20110201
Population pharmacokinetics of pregabalin in healthy subjects and patients with chronic pain or partial seizures. Epilepsia 20110201
Pregabalin-induced trismus in a leukemia patient. Journal of hospital medicine 20110201
Pregabalin effect on steady-state pharmacokinetics of carbamazepine, lamotrigine, phenobarbital, phenytoin, topiramate, valproate, and tiagabine. Epilepsia 20110201
Efficacy of pregabalin for peripheral neuropathic pain: results of an 8-week, flexible-dose, double-blind, placebo-controlled study conducted in China. Clinical therapeutics 20110201
Pregabalin attenuates place escape/avoidance behavior in a rat model of spinal cord injury. Brain research 20110125
Treatment of restless legs syndrome with pregabalin: a double-blind, placebo-controlled study. Neurology 20110125
Retrospective evaluation of clinical characteristics, pharmacotherapy and healthcare resource use among patients prescribed pregabalin or duloxetine for diabetic peripheral neuropathy in usual care. Pain practice : the official journal of World Institute of Pain 20110101
Simple and sensitive spectrofluorimetric method for the determination of pregabalin in capsules through derivatization with fluorescamine. Luminescence : the journal of biological and chemical luminescence 20110101
Comparison of medication adherence and healthcare costs between duloxetine and pregabalin initiators among patients with fibromyalgia. Pain practice : the official journal of World Institute of Pain 20110101
Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder. Neurourology and urodynamics 20110101
Gabapentin and pregabalin inhibit the itch-associated response induced by the repeated application of oxazolone in mice. Journal of pharmacological sciences 20110101
Efficacy and safety of pregabalin for treating neuropathic pain associated with diabetic peripheral neuropathy: a 14 week, randomized, double-blind, placebo-controlled trial. Diabetic medicine : a journal of the British Diabetic Association 20110101
Pregabalin for peripheral neuropathic pain: a multicenter, enriched enrollment randomized withdrawal placebo-controlled trial. The Clinical journal of pain 20110101
Effect of pregabalin in the treatment of refractory neck pain: cost and clinical evidence from medical practice in orthopedic surgery and rehabilitation clinics. Pain practice : the official journal of World Institute of Pain 20110101
Real-world evaluation of health-care resource utilization and costs in employees with fibromyalgia treated with pregabalin or duloxetine. Pain practice : the official journal of World Institute of Pain 20110101
Is there a recreational misuse potential for pregabalin? Analysis of anecdotal online reports in comparison with related gabapentin and clonazepam data. Psychotherapy and psychosomatics 20110101
A cost-consequences analysis of the effect of pregabalin in the treatment of peripheral neuropathic pain in routine medical practice in primary care settings. BMC neurology 20110101
Effect of a single dose of pregabalin on herpes zoster pain. Trials 20110101
Health outcomes and costs among employees with fibromyalgia treated with pregabalin vs. standard of care. Pain practice : the official journal of World Institute of Pain 20110101
Pregabalin in zolpidem dependence and withdrawal. Clinical neuropharmacology 20110101
Efficacy and tolerability of pregabalin versus topiramate in the prophylaxis of chronic daily headache with analgesic overuse: an open-label prospective study. Clinical neuropharmacology 20110101
Attenuating effect of Acorus calamus extract in chronic constriction injury induced neuropathic pain in rats: an evidence of anti-oxidative, anti-inflammatory, neuroprotective and calcium inhibitory effects. BMC complementary and alternative medicine 20110101
Clinical characteristics, pharmacotherapy, and healthcare resource use among patients with diabetic neuropathy newly prescribed pregabalin or gabapentin. Pain practice : the official journal of World Institute of Pain 20110101
Relationships between changes in pain severity and other patient-reported outcomes: an analysis in patients with posttraumatic peripheral neuropathic pain. Health and quality of life outcomes 20110101
7-Nitroindazole, but not NG-nitro-L-arginine, enhances the anticonvulsant activity of pregabalin in the mouse maximal electroshock-induced seizure model. Pharmacological reports : PR 20110101
Impact of pregabalin treatment on pain, pain-related sleep interference and general well-being in patients with neuropathic pain: a non-interventional, multicentre, post-marketing study. Clinical drug investigation 20110101
Treatment of neuropathic pain in patients with chronic kidney disease. CANNT journal = Journal ACITN 20110101
Trazodone plus pregabalin combination in the treatment of fibromyalgia: a two-phase, 24-week, open-label uncontrolled study. BMC musculoskeletal disorders 20110101
Long-term controlled-release oxycodone and pregabalin in the treatment of non-cancer pain: an observational study. European neurology 20110101
Eye-related visual hallucinations: consider 'Charles Bonnet syndrome'. Indian journal of ophthalmology 20110101
Interference with work in fibromyalgia: effect of treatment with pregabalin and relation to pain response. BMC musculoskeletal disorders 20110101
Effects of pregabalin on subjective sleep disturbance symptoms during withdrawal from long-term benzodiazepine use. European addiction research 20110101
[Benefits and safety of perioperative pregabalin: a systematic review]. Annales francaises d'anesthesie et de reanimation 20110101
Utility of certain nucleophilic aromatic substitution reactions for the assay of pregabalin in capsules. Chemistry Central journal 20110101
[Effect of pre-emptive pregabalin on pain intensity and morphine requirement after hysterectomy]. Anestezjologia intensywna terapia 20110101
Pregabalin in acute and chronic pain. Journal of anaesthesiology, clinical pharmacology 20110101
A translational study of the effects of ketamine and pregabalin on temporal summation of experimental pain. Regional anesthesia and pain medicine 20110101
Multimodal systemic and intra-articular analgesics. International anesthesiology clinics 20110101
A randomized controlled trial to compare pregabalin with gabapentin for postoperative pain in abdominal hysterectomy. Saudi journal of anaesthesia 20110101
The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain. Arthritis research & therapy 20110101
Effectiveness of cognitive behaviour therapy for the treatment of catastrophisation in patients with fibromyalgia: a randomised controlled trial. Arthritis research & therapy 20110101
Postoperative respiratory depression with pregabalin: a case series and a preoperative decision algorithm. Pain research & management 20110101
Analgesic effects of a single preoperative dose of pregabalin after laparoscopic sleeve gastrectomy. Obesity surgery 20101201
Significant pregabalin toxicity managed with supportive care alone. Journal of medical toxicology : official journal of the American College of Medical Toxicology 20101201
Central sensitization and Ca(V)α₂δ ligands in chronic pain syndromes: pathologic processes and pharmacologic effect. The journal of pain : official journal of the American Pain Society 20101201
The use of pregabalin in the treatment of uraemic pruritus in haemodialysis patients. Journal of renal care 20101201
Medical conditions in fibromyalgia patients and their relationship to pregabalin efficacy: pooled analysis of Phase III clinical trials. Expert opinion on pharmacotherapy 20101201
An enhanced bunionectomy model as a potential tool for early decision-making in the development of new analgesics. Advances in therapy 20101201
Gabapentin and pregabalin in the treatment of fibromyalgia: a systematic review and a meta-analysis. Journal of clinical pharmacy and therapeutics 20101201
Efficacy and tolerability of pregabalin using a flexible, optimized dose schedule in Korean patients with peripheral neuropathic pain: a 10-week, randomized, double-blind, placebo-controlled, multicenter study. Clinical therapeutics 20101201
[Yes, pregabalin can be abused!]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20101104
Liquid chromatographic separation of pregabalin and its possible impurities with fluorescence detection after postcolumn derivatization with o-phtaldialdehyde. Journal of pharmaceutical and biomedical analysis 20101102
Perioperative administration of pregabalin for pain after robot-assisted endoscopic thyroidectomy: a randomized clinical trial. Surgical endoscopy 20101101
Preemptive multimodal pain regimen reduces opioid analgesia for patients undergoing robotic-assisted laparoscopic radical prostatectomy. Urology 20101101
Pregabalin-induced severe delayed ejaculation. Epilepsy & behavior : E&B 20101101
Evaluation of pregabalin as an adjuvant to patient-controlled epidural analgesia during late termination of pregnancy. Anesthesiology 20101101
Compression of the superficial branch of the radial nerve by calcinosis cutis causing neuropathic pain. The Journal of hand surgery, European volume 20101101
Pregabalin for the treatment of postsurgical pain. Expert opinion on pharmacotherapy 20101101
[Puncture of the radial vein: a forgotten complication]. Annales francaises d'anesthesie et de reanimation 20101101
Does Pregabalin (Lyrica(®) ) help patients reduce their use of benzodiazepines? A comparison with gabapentin using the Norwegian Prescription Database. Basic & clinical pharmacology & toxicology 20101101
Oral pregabalin as an add-on treatment for status epilepticus. Epilepsia 20101001
An expert opinion on postoperative pain management, with special reference to new developments. Expert opinion on pharmacotherapy 20101001
Genotoxic evaluation of antiepileptic drugs by Drosophila somatic mutation and recombination test. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101001
Identification of subunits of voltage-gated calcium channels and actions of pregabalin on intrinsic primary afferent neurons in the guinea-pig ileum. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20101001
Additive interactions of pregabalin with lamotrigine, oxcarbazepine and topiramate in the mouse maximal electroshock-induced seizure model: a type I isobolographic analysis for non-parallel dose-response relationship curves. Epilepsy research 20101001
The effect of pregabalin on pain-related sleep interference in diabetic peripheral neuropathy or postherpetic neuralgia: a review of nine clinical trials. Current medical research and opinion 20101001
Treatment response to pregabalin in fibromyalgia pain: effect of patient baseline characteristics. Expert opinion on pharmacotherapy 20101001
A comparison of the pharmacokinetics and pharmacodynamics of pregabalin and gabapentin. Clinical pharmacokinetics 20101001
Potential for pregabalin abuse or diversion after past drug-seeking behavior. The Journal of the American Osteopathic Association 20101001
Pregabalin for the treatment of men with chronic prostatitis/chronic pelvic pain syndrome: a randomized controlled trial. Archives of internal medicine 20100927
Bitter pills for drug companies. BMJ (Clinical research ed.) 20100917
Pregabalin inhibits accelerated defecation and decreased colonic nociceptive threshold in sensitized rats. European journal of pharmacology 20100915
[Abuse of pregabalin]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20100909
Pregabalin versus naltrexone in alcohol dependence: a randomised, double-blind, comparison trial. Journal of psychopharmacology (Oxford, England) 20100901
Treatment of post-burn neuropathic pain: evaluation of pregablin. Burns : journal of the International Society for Burn Injuries 20100901
The efficacy and safety of pregabalin in the treatment of neuropathic pain associated with chronic lumbosacral radiculopathy. Pain 20100901
A signal for an abuse liability for pregabalin--results from the Swedish spontaneous adverse drug reaction reporting system. European journal of clinical pharmacology 20100901
Back pain is complicated. Pain 20100901
Pregabalin and transcutaneous electrical nerve stimulation for postherpetic neuralgia treatment. The Clinical journal of pain 20100901
A comparison of pregabalin, lamotrigine, and placebo as adjunctive therapy in patients with refractory partial-onset seizures. Epilepsy research 20100901
[Pharmacology profile and clinical findings of pregabalin (Lyrica capsule)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100901
Models for event-driven data: longitudinal daily adverse event and dropout. Journal of clinical pharmacology 20100901
Osseous metaplasia late in the course of nephrogenic systemic fibrosis. Dermatology online journal 20100815
Clinical pharmacokinetics of pregabalin in healthy volunteers. Journal of clinical pharmacology 20100801
Pregabalin as mono- or add-on therapy for patients with refractory chronic neuropathic pain: a post-marketing prescription-event monitoring study. Journal of neurology 20100801
Pregabalin in the treatment of post-traumatic peripheral neuropathic pain: a randomized double-blind trial. European journal of neurology 20100801
Pharmacokinetic-pharmacodynamic analysis of the static allodynia response to pregabalin and sildenafil in a rat model of neuropathic pain. The Journal of pharmacology and experimental therapeutics 20100801
A prospective, open-label, multicentre study of pregabalin in the treatment of neuropathic pain in Latin America. International journal of clinical practice 20100801
Augmentation with pregabalin in schizophrenia. Journal of clinical psychopharmacology 20100801
Use of low-dose pregabalin in patients undergoing laparoscopic cholecystectomy. British journal of anaesthesia 20100801
[Long-term efficacy and safety of pregabalin in patients with postherpetic neuralgia: results of a 52-week, open-label, flexible-dose study]. Masui. The Japanese journal of anesthesiology 20100801
Treating diabetic peripheral neuropathic pain. American family physician 20100715
[Evidence-based recommendations for the treatment of fibromyalgia syndrome]. Zeitschrift fur Rheumatologie 20100701
Exposure-response analyses of the effects of pregabalin in patients with fibromyalgia using daily pain scores and patient global impression of change. Journal of clinical pharmacology 20100701
Pain, in the boondocks. Canadian journal of anaesthesia = Journal canadien d'anesthesie 20100701
Post-herpetic neuralgia: 5% lidocaine medicated plaster, pregabalin, or a combination of both? A randomized, open, clinical effectiveness study. Current medical research and opinion 20100701
Attenuation of neuropathy-induced allodynia following intraplantar injection of pregabalin. Canadian journal of anaesthesia = Journal canadien d'anesthesie 20100701
Pregabalin and edema in young women suffering from premenstrual syndrome. Pharmacopsychiatry 20100701
The alpha2-delta protein: an auxiliary subunit of voltage-dependent calcium channels as a recognized drug target. Current opinion in investigational drugs (London, England : 2000) 20100701
Pregabalin abuse, dependence, and withdrawal: a case report. The American journal of psychiatry 20100701
[Unreliable about drug industry]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20100701
Pregabalin and gabapentin in matched patients with peripheral neuropathic pain in routine medical practice in a primary care setting: Findings from a cost-consequences analysis in a nested case-control study. Clinical therapeutics 20100701
Role of pregabalin in treatment of oxaliplatin-induced sensory neuropathy. Anticancer research 20100701
Treatment of restless legs syndrome with pregabalin: a double-blind, placebo-controlled study. Neurology 20100608
Patient-reported-outcomes in subjects with painful lumbar or cervical radiculopathy treated with pregabalin: evidence from medical practice in primary care settings. Rheumatology international 20100601
Severe and disabling constipation: an adverse effect of pregabalin. Epilepsia 20100601
Long-term add-on pregabalin treatment in patients with partial-onset epilepsy: pooled analysis of open-label clinical trials. Epilepsia 20100601
Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome. The journal of pain : official journal of the American Pain Society 20100601
A randomized, double-blind, 6-week, dose-ranging study of pregabalin in patients with restless legs syndrome. Sleep medicine 20100601
Why pregabalin? Drug and therapeutics bulletin 20100601
Healthcare utilization and cost effects of prior authorization for pregabalin in commercial health plans. The American journal of managed care 20100601
Oxycodone combinations for pain relief. Drugs of today (Barcelona, Spain : 1998) 20100601
[Can we rely on drug industry?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20100520
[Questionable documentation of the effect of pregabalin in fibromyalgia]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20100520
A randomized, controlled trial of oxycodone versus placebo in patients with postherpetic neuralgia and painful diabetic neuropathy treated with pregabalin. The journal of pain : official journal of the American Pain Society 20100501
Pregabalin in partial seizures: a pragmatic 21-week, open-label study (PREPS). European journal of neurology 20100501
Interactions of 1-methyl-1,2,3,4-tetrahydroisoquinoline with lamotrigine, oxcarbazepine, pregabalin, and topiramate in the mouse maximal electroshock-induced seizure model: a type I isobolographic analysis. Epilepsy research 20100501
How do changes in pain severity levels correspond to changes in health status and function in patients with painful diabetic peripheral neuropathy? Pain 20100501
Patient-reported outcomes in subjects with neuropathic pain receiving pregabalin: evidence from medical practice in primary care settings. Pain medicine (Malden, Mass.) 20100501
Cut-points for the measurement of pain: the choice depends on what you want to study. Pain 20100501
Fibromyalgia: Moderate and substantial pain intensity reduction predicts improvement in other outcomes and substantial quality of life gain. Pain 20100501
Pregabalin treatment of anxiety in patients with substance use disorders. The Annals of pharmacotherapy 20100501
Effects of pregabalin on acute herpetic pain and postherpetic neuralgia incidence. Wiener klinische Wochenschrift 20100501
Pregabalin: an alpha2-delta (alpha2-delta) ligand for the management of fibromyalgia. The American journal of managed care 20100501
Initial use of pregabalin, patterns of pain-related pharmacotherapy, and healthcare resource use among older patients with fibromyalgia. The American journal of managed care 20100501
Impact of a prior authorization for pregabalin on health plan drug expenditures. The American journal of managed care 20100501
Pregabalin in fibromyalgia: meta-analysis of efficacy and safety from company clinical trial reports. Rheumatology (Oxford, England) 20100401
Synthesis, characterization and in vitro pharmacology of novel pregabalin derivatives. European journal of medicinal chemistry 20100401
Perioperative pregabalin improves pain and functional outcomes 3 months after lumbar discectomy. Anesthesia and analgesia 20100401
Evidence that pregabalin reduces neuropathic pain by inhibiting the spinal release of glutamate. Journal of neurochemistry 20100401
A prospective evaluation of 2 different pain management protocols for total hip arthroplasty. The Journal of arthroplasty 20100401
Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective. Current medical research and opinion 20100401
The anti-allodynic alpha(2)delta ligand pregabalin inhibits the trafficking of the calcium channel alpha(2)delta-1 subunit to presynaptic terminals in vivo. Biochemical Society transactions 20100401
Pregabalin in outpatient detoxification of subjects with mild-to-moderate alcohol withdrawal syndrome. Human psychopharmacology 20100401
Psychiatric concerns in pediatric epilepsy. Child and adolescent psychiatric clinics of North America 20100401
[No evidence for tolerance in the treatment of anxiety with pregabalin (Lyrica)]. Lakartidningen 20100401
[Is postoperative pain only a nociceptive pain?]. Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20100401
Pregabalin in the treatment of neuropathic tremor following a motor axonal form of Guillain-Barré syndrome. Movement disorders : official journal of the Movement Disorder Society 20100315
Separation and characterization of modified pregabalins in terms of cyclodextrin complexation, using capillary electrophoresis and nuclear magnetic resonance. Journal of pharmaceutical and biomedical analysis 20100311
Cognitive effects of pregabalin in healthy volunteers: a double-blind, placebo-controlled trial. Neurology 20100302
Comparative efficacy of pregabalin and benzodiazepines in treating the psychic and somatic symptoms of generalized anxiety disorder. The international journal of neuropsychopharmacology 20100301
Substitution of gabapentin therapy with pregabalin therapy in neuropathic pain due to peripheral neuropathy. Pain medicine (Malden, Mass.) 20100301
Recommendations for the pharmacological management of neuropathic pain: an overview and literature update. Mayo Clinic proceedings 20100301
Treating anxiety without SSRIs. The Journal of family practice 20100301
[Pregabalin (Lyrica) prescription must be cost-effective]. Lakartidningen 20100301
[Just the costs which spin?]. Lakartidningen 20100301
[A reply from Pfizer: Relevant questions, but wrong examples!]. Lakartidningen 20100301
Pregabalin for painful HIV neuropathy: a randomized, double-blind, placebo-controlled trial. Neurology 20100202
Cost-effectiveness of pregabalin versus venlafaxine in the treatment of generalized anxiety disorder: findings from a Spanish perspective. The European journal of health economics : HEPAC : health economics in prevention and care 20100201
Comparison of milnacipran, duloxetine and pregabalin in the formalin pain test and in a model of stress-induced ultrasonic vocalizations in rats. Neuroscience research 20100201
Phase III, randomized, double-blind, placebo-controlled evaluation of pregabalin for alleviating hot flashes, N07C1. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100201
Carbamazepine but not pregabalin impairs eye control: a study on acute objective CNS side effects in healthy volunteers. Epilepsy research 20100201
Experience in the use of the anticonvulsant pregabalin as an add-on therapy in patients with partial epilepsy with polymorphic seizures. Neuroscience and behavioral physiology 20100201
Pregabalin, tiapride and lorazepam in alcohol withdrawal syndrome: a multi-centre, randomized, single-blind comparison trial. Addiction (Abingdon, England) 20100201
Pregabalin for generalised anxiety disorder. Drug and therapeutics bulletin 20100201
A new combination cream for the treatment of severe neuropathic pain. Journal of pain and symptom management 20100201
Evidence for sensory neuropathy and pharmacologic management. Otolaryngologic clinics of North America 20100201
[TLV scrutinizes pregabalin (Lyrica)]. Lakartidningen 20100201
[Why does the cost of pregabalin (Lyrica) spin?]. Lakartidningen 20100201
[Treatment of neuropathies]. Orvosi hetilap 20100110
Perioperative oral pregabalin reduces chronic pain after total knee arthroplasty: a prospective, randomized, controlled trial. Anesthesia and analgesia 20100101
Pregabalin in the treatment of chronic migraine: an open-label study. Clinical neuropharmacology 20100101
Pharmacological treatment of fibromyalgia syndrome: new developments. Drugs 20100101
Drugs to treat fibromyalgia - the transatlantic difference. Current opinion in investigational drugs (London, England : 2000) 20100101
Comparative study of clinical efficacy with amitriptyline, pregabalin, and amitriptyline plus pregabalin combination in postherpetic neuralgia. Indian journal of dermatology, venereology and leprology 20100101
Cost effectiveness of a lidocaine 5% medicated plaster compared with pregabalin for the treatment of postherpetic neuralgia in the UK: a Markov model analysis. Clinical drug investigation 20100101
Pregabalin in the treatment of alcohol and benzodiazepines dependence. CNS neuroscience & therapeutics 20100101
[Therapeutic drug monitoring of pregabaline]. Therapie 20100101
A presumed case of phantom limb pain treated successfully with duloxetine and pregabalin. General hospital psychiatry 20100101
[Hepatic adverse effects of pregabalin (Lyrica)]. Lakartidningen 20100101
Interaction of pregabalin with carbamazepine in the mouse maximal electroshock-induced seizure model: a type I isobolographic analysis for non-parallel dose-response relationship curves. Advances in medical sciences 20100101
Time to onset of neuropathic pain reduction: A retrospective analysis of data from nine controlled trials of pregabalin for painful diabetic peripheral neuropathy and postherpetic neuralgia. American journal of therapeutics 20100101
A cost-consequence analysis of pregabalin versus usual care in the symptomatic treatment of refractory low back pain: sub-analysis of observational trial data from orthopaedic surgery and rehabilitation clinics. Clinical drug investigation 20100101
Pregabalin in fibromyalgia--responder analysis from individual patient data. BMC musculoskeletal disorders 20100101
A cost-consequences analysis of the effect of pregabalin in the treatment of painful radiculopathy under medical practice conditions in primary care settings. Pain practice : the official journal of World Institute of Pain 20100101
Comparing healthcare costs of Medicaid patients with postherpetic neuralgia (PHN) treated with lidocaine patch 5% versus gabapentin or pregabalin. Journal of medical economics 20100101
Rapid high-performance liquid chromatography method for determination of pregabalin in a pharmaceutical dosage form following derivatization with fluorescamine. Journal of AOAC International 20100101
Can a single dose of 300 mg of pregabalin reach acute antihyperalgesic levels in the central nervous system? Regional anesthesia and pain medicine 20100101
Pregabalin versus gabapentin in partial epilepsy: a meta-analysis of dose-response relationships. BMC neurology 20100101
Relationships among pain and depressive and anxiety symptoms in clinical trials of pregabalin in fibromyalgia. Psychosomatics 20100101
Evaluation of the safety and efficacy of pregabalin in older patients with neuropathic pain: results from a pooled analysis of 11 clinical studies. BMC family practice 20100101
Evaluation of healthcare resource utilization and costs in employees with pain associated with diabetic peripheral neuropathy treated with pregabalin or duloxetine. Journal of medical economics 20100101
Pregabalin, the lidocaine plaster and duloxetine in patients with refractory neuropathic pain: a systematic review. BMC neurology 20100101
Dose-response relationship analysis of pregabalin doses and their antinociceptive effects in hot-plate test in mice. Pharmacological reports : PR 20100101
Acute modulation of calcium currents and synaptic transmission by gabapentinoids. Channels (Austin, Tex.) 20100101
Pregabalin antagonizes copper-induced toxicity in the brain: in vitro and in vivo studies. Neuro-Signals 20100101
[Lyrica (pregabalin) in the treatment of focal refractory epilepsy in adults]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
Selective inhibitory effects of pregabalin on peripheral C but not A-delta fibers mediated nociception in intact and spinalized rats. Neuroscience 20091229
ECG variations in patients pre- and post-local anaesthesia and analgesia. British dental journal 20091219
Proteomic analysis to identify early molecular targets of pregabalin in C6 glial cells. Cell biology international 20091216
Analgesic efficacy of tramadol, pregabalin and ibuprofen in menthol-evoked cold hyperalgesia. Pain 20091215
Pregabalin as an adjunct to phenobarbital, potassium bromide, or a combination of phenobarbital and potassium bromide for treatment of dogs with suspected idiopathic epilepsy. Journal of the American Veterinary Medical Association 20091215
Treatment of pregabalin toxicity by hemodialysis in a patient with kidney failure. American journal of kidney diseases : the official journal of the National Kidney Foundation 20091201
Pain management after ambulatory surgery. Current opinion in anaesthesiology 20091201
The long-term retention of pregabalin in a large cohort of patients with epilepsy at a tertiary referral centre. Epilepsy research 20091201
Pregabalin as treatment for fibromyalgia: the rest of the story? Current pain and headache reports 20091201
Joint modeling of dizziness, drowsiness, and dropout associated with pregabalin and placebo treatment of generalized anxiety disorder. Journal of pharmacokinetics and pharmacodynamics 20091201
Pregabalin, celecoxib, and their combination for treatment of chronic low-back pain. Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20091201
A treatment algorithm for neuropathic pain: an update. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20091201
Liquid chromatography atmospheric pressure chemical ionization tandem mass spectrometry method for the quantification of pregabalin in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091115
Smooth muscle cell alpha2delta-1 subunits are essential for vasoregulation by CaV1.2 channels. Circulation research 20091106
Early onset anxiolytic efficacy after a single dose of pregabalin: double-blind, placebo- and active-comparator controlled evaluation using a dental anxiety model. Journal of psychopharmacology (Oxford, England) 20091101
Retention rate of pregabalin in drug-resistant epilepsy: 1-year follow-up, single-centre observation in 105 consecutive, adult patients. Seizure 20091101
Pharmacokinetics of single-dose oral pregabalin administration in normal dogs. Veterinary anaesthesia and analgesia 20091101
Hyponatremia and confusion caused by pregabalin. The Israel Medical Association journal : IMAJ 20091101
Efficacy and tolerability of pregabalin in essential tremor: a randomized, double-blind, placebo-controlled, crossover trial. Journal of the neurological sciences 20091015
Pregabalin- and gabapentin-associated myoclonus in a patient with chronic renal failure. Movement disorders : official journal of the Movement Disorder Society 20091015
Pregabalin for treating paroxysmal painful symptoms in multiple sclerosis: a pilot study. Journal of neurology 20091001
An evaluation of perioperative pregabalin for prevention and attenuation of postoperative shoulder pain after laparoscopic cholecystectomy. Anesthesia and analgesia 20091001
Population pharmacokinetic model of the pregabalin-sildenafil interaction in rats: application of simulation to preclinical PK-PD study design. Pharmaceutical research 20091001
Fibromyalgia and headache disorders. Current pain and headache reports 20091001
Current progress in the pharmacological therapy of fibromyalgia. Expert opinion on investigational drugs 20091001
Marked response of burning mouth syndrome to pregabalin treatment. Clinical and experimental dermatology 20091001
Treatment of neuropathic pain: an overview of recent guidelines. The American journal of medicine 20091001
Effects of a Medicaid prior authorization policy for pregabalin. The American journal of managed care 20091001
Effects of pregabalin on post operative morphine consumption and pain after abdominal hysterectomy with/without salphingo-oophorectomy: a randomized, double-blind trial. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20091001
Amitriptyline vs. pregabalin in painful diabetic neuropathy: a randomized double blind clinical trial. Diabetic medicine : a journal of the British Diabetic Association 20091001
[Pregabalin--profile of efficacy and tolerability in neuropathic pain]. Drugs of today (Barcelona, Spain : 1998) 20091001
Treatment of fibromyalgia syndrome with gabapentin and pregabalin--a meta-analysis of randomized controlled trials. Pain 20090901
A new treatment option for laryngeal sensory neuropathy. The Laryngoscope 20090901
Successful pain relief of cutaneous leiomyomata due to reed syndrome with the combination treatment of pregabalin and duloxetine. Journal of pain and symptom management 20090901
Combined use of pregabalin and memantine in fibromyalgia syndrome treatment: a novel analgesic and neuroprotective strategy? Medical hypotheses 20090801
Rapid onset of seizure suppression with pregabalin adjunctive treatment in patients with partial seizures. Epilepsia 20090801
Pregabalin: a new approach to treatment of the dysautonomic crisis. Pediatrics 20090801
Pregabalin for fibromyalgia. Cleveland Clinic journal of medicine 20090801
Diagnosing and treating fibromyalgia. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20090801
Gabapentin and pregabalin for the acute post-operative pain management. A systematic-narrative review of the recent clinical evidences. Current drug targets 20090801
Oxaliplatin-induced hyperexcitability syndrome in a patient with pancreatic cancer. JOP : Journal of the pancreas 20090706
Efficacy of pregabalin in neuropathic pain in paediatric oncological patients. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20090701
Pregabalin as adjunctive therapy for partial epilepsy: an audit study in 96 patients from the South East of England. Seizure 20090701
Validating a human model for anxiety using startle potentiated by cue and context: the effects of alprazolam, pregabalin, and diphenhydramine. Psychopharmacology 20090701
Efficacy and safety of combination therapy with 5% lidocaine medicated plaster and pregabalin in post-herpetic neuralgia and diabetic polyneuropathy. Current medical research and opinion 20090701
5% lidocaine medicated plaster versus pregabalin in post-herpetic neuralgia and diabetic polyneuropathy: an open-label, non-inferiority two-stage RCT study. Current medical research and opinion 20090701
Patient-reported outcomes in subjects with painful trigeminal neuralgia receiving pregabalin: evidence from medical practice in primary care settings. Cephalalgia : an international journal of headache 20090701
The efficacy of pregabalin and benzodiazepines in generalized anxiety disorder presenting with high levels of insomnia. International clinical psychopharmacology 20090701
Multimodal analgesia for hip arthroplasty. The Orthopedic clinics of North America 20090701
Minimal clinically important difference in the fibromyalgia impact questionnaire. The Journal of rheumatology 20090601
The effects of pregabalin on sleep disturbance symptoms among individuals with fibromyalgia syndrome. Sleep medicine 20090601
Gabapentin and pregabalin ameliorate mechanical hypersensitivity after spinal cord injury in mice. European journal of pharmacology 20090501
Trigeminal neuralgia treated with pregabalin in family medicine settings: its effect on pain alleviation and cost reduction. Journal of clinical pharmacology 20090501
Impact of gastrointestinal symptoms on response to pregabalin in generalized anxiety disorder: results of a six-study combined analysis. International clinical psychopharmacology 20090501
Pregabalin: preliminary experience in intractable childhood epilepsy. Pediatric neurology 20090501
Medicinal chemistry strategies in follow-on drug discovery. Drug discovery today 20090501
Pregabalin in the treatment of schizophrenic anxiety. Pharmacopsychiatry 20090501
Pregabalin augmentation to antidepressants in patients with major depressive disorder. Progress in neuro-psychopharmacology & biological psychiatry 20090430
Add-on treatment with pregabalin for partial seizures with or without generalisation: pooled data analysis of four randomised placebo-controlled trials. Seizure 20090401
Effects of gabapentin and pregabalin on K+-evoked 3H-GABA and 3H-glutamate release from human neocortical synaptosomes. Naunyn-Schmiedeberg's archives of pharmacology 20090401
[New antiepileptic drugs]. La Revue de medecine interne 20090401
All results count. Anesthesia and analgesia 20090401
The effect of pregabalin on preoperative anxiety and sedation levels: a dose-ranging study. Anesthesia and analgesia 20090401
The increased trafficking of the calcium channel subunit alpha2delta-1 to presynaptic terminals in neuropathic pain is inhibited by the alpha2delta ligand pregabalin. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090401
Pregabalin for fibromyalgia: some relief but no cure. Cleveland Clinic journal of medicine 20090401
Etodolac attenuates mechanical allodynia in a mouse model of neuropathic pain. Journal of pharmacological sciences 20090401
Mechanisms of analgesia by gabapentin and pregabalin--calcium channel alpha2-delta [Cavalpha2-delta] ligands. Pain 20090301
Pain in the numb chin syndrome. Headache 20090301
Pregabalin add-on therapy using a flexible, optimized dose schedule in refractory partial epilepsies: a double-blind, randomized, placebo-controlled, multicenter trial. Epilepsia 20090301
Oral pregabalin reverses cold allodynia in two distinct models of peripheral neuropathic pain. European journal of pharmacology 20090301
Usher syndrome and psychiatric symptoms: a challenge in psychiatric management. Psychiatria Danubina 20090301
Modeling subpopulations with the $MIXTURE subroutine in NONMEM: finding the individual probability of belonging to a subpopulation for the use in model analysis and improved decision making. The AAPS journal 20090301
[Empirical evidence for the use of anticonvulsants in personality disorders]. Fortschritte der Neurologie-Psychiatrie 20090301
Metabolic considerations in a case of pregabalin-induced edema. Pharmacopsychiatry 20090301
Efficacy of pregabalin and venlafaxine-XR in generalized anxiety disorder: results of a double-blind, placebo-controlled 8-week trial. International clinical psychopharmacology 20090301
Spectrophotometric and spectrofluorimetric methods for the determination of pregabalin in bulk and pharmaceutical preparation. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090201
Anxiolytic profile of pregabalin on elicited hippocampal theta oscillation. Neuropharmacology 20090201
Pregabalin in patients with primary brain tumors and seizures: a preliminary observation. Clinical neurology and neurosurgery 20090201
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. Acta anaesthesiologica Scandinavica 20090201
Pregabalin (Lyrica, Pfizer, Inc.). Issues in mental health nursing 20090201
Expert opinion. Supraorbital neuralgia. Headache 20090201
[Irritable bowel syndrome: dietary and pharmacological therapeutic options]. Gastroenterologie clinique et biologique 20090201
[Pregabalin and its potential for abuse]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090129
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Botulinum toxin treatment of epilepsia partialis continua. Movement disorders : official journal of the Movement Disorder Society 20090115
Duloxetine: an emerging evidence for fibromyalgia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090101
Oxadiazolone bioisosteres of pregabalin and gabapentin. Bioorganic & medicinal chemistry letters 20090101
Use of pregabalin in patients with painful neuropathic disorders under the care of general practitioners in the U.K. Pain practice : the official journal of World Institute of Pain 20090101
Pregabalin for acute pain management: a shift in paradigm. British journal of anaesthesia 20090101
Pregabalin augmentation of antidepressants in patients with accident-related posttraumatic stress disorder: an open label pilot study. International clinical psychopharmacology 20090101
Simultaneous determination of three anticonvulsants using hydrophilic interaction LC-MS. Journal of separation science 20090101
Pregabalin as add-on therapy induces REM sleep enhancement in partial epilepsy: a polysomnographic study. European journal of neurology 20090101
Controlled-release oxycodone and pregabalin in the treatment of neuropathic pain: results of a multicenter Italian study. European neurology 20090101
Meta-analysis of duloxetine vs. pregabalin and gabapentin in the treatment of diabetic peripheral neuropathic pain. BMC neurology 20090101
Pregabalin in the treatment of chronic pain: an overview. Clinical drug investigation 20090101
Efficacy and safety of 5% lidocaine (lignocaine) medicated plaster in comparison with pregabalin in patients with postherpetic neuralgia and diabetic polyneuropathy: interim analysis from an open-label, two-stage adaptive, randomized, controlled trial. Clinical drug investigation 20090101
Effectiveness of the psychological and pharmacological treatment of catastrophization in patients with fibromyalgia: a randomized controlled trial. Trials 20090101
Adjunctive pregabalin to quetiapine in acute mania. Clinical neuropharmacology 20090101
Clinical characteristics, pharmacotherapy and healthcare resource use among patients with fibromyalgia newly prescribed gabapentin or pregabalin. Pain practice : the official journal of World Institute of Pain 20090101
Treatment of postherpetic neuralgia: focus on pregabalin. Clinical interventions in aging 20090101
Lyrica cures the tenor. Clinical neuropharmacology 20090101
Psychometric properties of a single-item scale to assess sleep quality among individuals with fibromyalgia. Health and quality of life outcomes 20090101
Pain responder analysis: use of area under the curve to enhance interpretation of clinical trial results. Pain practice : the official journal of World Institute of Pain 20090101
Pregabalin for acute and chronic pain in adults. The Cochrane database of systematic reviews 20090101
Acute delirium in patients with multiple sclerosis treated with pregabalin. Clinical neuropharmacology 20090101
Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain. Molecular pain 20090101
[Pregabalin in the polytherapy of partial epilepsy]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
Pregabalin: in the treatment of postherpetic neuralgia. Drugs & aging 20090101
Pregabalin-induced parkinsonism: a case report. Clinical neuropharmacology 20090101
Pregabalin for treating bipolar mania. Clinical neuropharmacology 20090101
Pregabalin in the treatment of benzodiazepine-induced obsessive-compulsive disorder. Progress in neuro-psychopharmacology & biological psychiatry 20081212
Defining neuralgiform headache with ipsilateral autonomic symptoms: case report in a headache center. Internal and emergency medicine 20081201
Is there a role for anticonvulsants in the management of rheumatic pain? Joint, bone, spine : revue du rhumatisme 20081201
Rash associated with pregabalin use. The Annals of pharmacotherapy 20081201
Effect of morphine and pregabalin compared with diphenhydramine hydrochloride and placebo on hyperalgesia and allodynia induced by intradermal capsaicin in healthy male subjects. The journal of pain : official journal of the American Pain Society 20081201
Gabapentin and post-thoracotomy shoulder pain. Canadian journal of anaesthesia = Journal canadien d'anesthesie 20081201
Fibromyalgia coverage uneven despite recent drug approvals. Managed care (Langhorne, Pa.) 20081201
Neuropathic pevic pain--a personal experience. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20081201
Pain relief by gabapentin and pregabalin via supraspinal mechanisms after peripheral nerve injury. Journal of neuroscience research 20081115
Descending facilitation from the brainstem determines behavioural and neuronal hypersensitivity following nerve injury and efficacy of pregabalin. Pain 20081115
Pregabalin in the treatment of refractory neuropathic pain: results of a 15-month open-label trial. Pain medicine (Malden, Mass.) 20081101
Dercum's disease (Lipomatosis dolorosa): successful therapy with pregabalin and manual lymphatic drainage and a current overview. Rheumatology international 20081101
Pregabalin for postherpetic neuralgia: placebo-controlled trial of fixed and flexible dosing regimens on allodynia and time to onset of pain relief. The journal of pain : official journal of the American Pain Society 20081101
Pregabalin overdose with benign outcome. Clinical toxicology (Philadelphia, Pa.) 20081101
Evaluation of a single preoperative dose of pregabalin for attenuation of postoperative pain after laparoscopic cholecystectomy. British journal of anaesthesia 20081101
Reduction of secondarily generalized tonic-clonic (SGTC) seizures with pregabalin. Epilepsy research 20081101
Development and validation of a direct enantiomeric separation of pregabalin to support isolated perfused rat kidney studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081101
Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder. The British journal of psychiatry : the journal of mental science 20081101
Response to: Long-term trials of pregabalin and duloxetine for fibromyalgia symptoms: How study designs can affect placebo factors. Pain 20081015
Efficacy and safety of pregabalin in patients with diabetic peripheral neuropathy or postherpetic neuralgia: Open-label, non-comparative, flexible-dose study. European journal of pain (London, England) 20081001
Effects of pregabalin on visceral pain responses and colonic compliance in rats. British journal of pharmacology 20081001
Adjunctive pregabalin therapy in mentally retarded, developmentally delayed patients with epilepsy. Epilepsy & behavior : E&B 20081001
Comparative antiallodynic activity of morphine, pregabalin and lidocaine in a rat model of neuropathic pain produced by one oxaliplatin injection. Neuropharmacology 20081001
Pregabalin and gabapentin inhibit substance P-induced NF-kappaB activation in neuroblastoma and glioma cells. Journal of cellular biochemistry 20081001
Pregabalin and dexamethasone for postoperative pain control: a randomized controlled study in hip arthroplasty. British journal of anaesthesia 20081001
Pregabalin as a probable cause of acute liver injury. European journal of gastroenterology & hepatology 20081001
Pregabalin treatment of posttraumatic stress disorder. Journal of clinical psychopharmacology 20081001
Diagnosis and treatment of glossopharyngeal and vagal neuropathies in a patient with laryngopharyngeal reflux. Anesthesiology 20081001
Pregabalin: a treatment for fibromyalgia and other painful conditions. Nursing for women's health 20081001
Pregabalin for the treatment of trigeminal neuralgia. American family physician 20081001
Efficacy and safety of pregabalin in neuropathic pain treatment: a still unreported adverse effect. Minerva medica 20081001
[Jaundice induced by treatment with pregabalin]. Medicina clinica 20080927
Potential role of pregabalin in the treatment of lithium-induced tremor: a case report. The international journal of neuropsychopharmacology 20080901
A 14-week, randomized, double-blinded, placebo-controlled monotherapy trial of pregabalin in patients with fibromyalgia. The journal of pain : official journal of the American Pain Society 20080901
Brief post-stressor treatment with pregabalin in an animal model for PTSD: short-term anxiolytic effects without long-term anxiogenic effect. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080901
Efficacy of pregabalin and gabapentin for neuropathic pain in spinal-cord injury: an evidence-based evaluation of the literature. European journal of clinical pharmacology 20080901
Possible heart failure exacerbation associated with pregabalin: case discussion and literature review. Journal of cardiovascular medicine (Hagerstown, Md.) 20080901
[Mechanisms of the development of neuropathic pain and its treatment]. Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20080901
Enriched enrollment: definition and effects of enrichment and dose in trials of pregabalin and gabapentin in neuropathic pain. A systematic review. British journal of clinical pharmacology 20080801
Central retinal vein occlusion with non-arteritic ischemic optic neuropathy and cystoid macular edema. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080801
Pregabalin-induced cortical negative myoclonus in a patient with neuropathic pain. Epilepsy & behavior : E&B 20080801
Decompensation of chronic heart failure associated with pregabalin in a 73-year-old patient with postherpetic neuralgia: a case report. British journal of clinical pharmacology 20080801
Efficacy and tolerability of pregabalin in patients with difficult-to-treat epilepsy and intellectual disability. Epilepsy & behavior : E&B 20080801
Exposure-response analysis for spontaneously reported dizziness in pregabalin-treated patient with generalized anxiety disorder. Clinical pharmacology and therapeutics 20080701
Efficacy, safety, and tolerability of pregabalin treatment for painful diabetic peripheral neuropathy: findings from seven randomized, controlled trials across a range of doses. Diabetes care 20080701
Update on fibromyalgia therapy. The American journal of medicine 20080701
Efficacy and tolerability of pregabalin in partial epilepsy. Expert review of neurotherapeutics 20080701
Bodyweight gain under pregabalin therapy in epilepsy: mitigation by counseling patients? Seizure 20080601
Pregabalin in the discontinuation of long-term benzodiazepines' use. Human psychopharmacology 20080601
Pregabalin as a neuroprotector after spinal cord injury in rats. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20080601
Efficacy of pregabalin in depressive symptoms associated with generalized anxiety disorder: a pooled analysis of 6 studies. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20080601
Long-term trials of pregabalin and duloxetine for fibromyalgia symptoms: how study designs can affect placebo factors. Pain 20080601
Fibromyalgia relapse evaluation and efficacy for durability of meaningful relief (FREEDOM): a 6-month, double-blind, placebo-controlled trial with pregabalin. Pain 20080601
Premedication with pregabalin 75 or 150 mg with ibuprofen to control pain after day-case gynaecological laparoscopic surgery. British journal of anaesthesia 20080601
Acute pregabalin reversal of citalopram-induced sexual dysfunction in generalized anxiety disorder. Journal of clinical psychopharmacology 20080601
Efficacy and safety of pregabalin in alcohol dependence. Advances in therapy 20080601
Pregabalin in patients with central neuropathic pain: a randomized, double-blind, placebo-controlled trial of a flexible-dose regimen. Pain 20080501
Pregabalin induced neutropenia. Progress in neuro-psychopharmacology & biological psychiatry 20080401
[Drugs for controversial diseases]. Lakartidningen 20080401
Rats with chronic post-ischemia pain exhibit an analgesic sensitivity profile similar to human patients with complex regional pain syndrome--type I. European journal of pharmacology 20080331
Cost-effectiveness of add-on therapy with pregabalin in patients with refractory partial epilepsy. Epilepsia 20080301
Successful amelioration of oxaliplatin-induced hyperexcitability syndrome with the antiepileptic pregabalin in a patient with pancreatic cancer. Cancer chemotherapy and pharmacology 20080301
Role of retinal hypoxia in diabetic macular edema: a new concept. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080301
A randomized, double-blind, placebo-controlled, phase III trial of pregabalin in the treatment of patients with fibromyalgia. The Journal of rheumatology 20080301
Pregabalin in the discontinuation of long-term benzodiazepine use: a case-series. International clinical psychopharmacology 20080301
[Cholestasis associated with pregabalin treatment]. Medicina clinica 20080209
Diabetic neuropathy: new strategies for treatment. Diabetes, obesity & metabolism 20080201
Pregabalin for relief of neuropathic pain associated with diabetic neuropathy: a randomized, double-blind study. European journal of pain (London, England) 20080201
[Should we care about pregabalin for elderly patients with a history of cardiac dysrhythmia?]. La Revue de medecine interne 20080201
Efficacy of pregabalin in the treatment of trigeminal neuralgia. Cephalalgia : an international journal of headache 20080201
Pregabalin in the treatment of chronic pruritus. Journal of the American Academy of Dermatology 20080201
Pharmacologic investigation of the mechanism underlying cold allodynia using a new cold plate procedure in rats with chronic constriction injuries. Behavioural pharmacology 20080201
Recent developments in the therapy of irritable bowel syndrome. Expert opinion on investigational drugs 20080201
A randomized controlled trial of perioperative administration of pregabalin for pain after laparoscopic hysterectomy. Pain 20080101
Pregabalin in the treatment of spasticity: a retrospective case series. Disability and rehabilitation 20080101
Differential modulation of K(+)-evoked (3)H-neurotransmitter release from human neocortex by gabapentin and pregabalin. Naunyn-Schmiedeberg's archives of pharmacology 20080101
Long-term efficacy of pregabalin in generalized anxiety disorder. International clinical psychopharmacology 20080101
Determination of optical impurity of pregabalin by HPLC with pre-column chiral derivatization. Journal of chromatographic science 20080101
Pregabalin add-on for drug-resistant partial epilepsy. The Cochrane database of systematic reviews 20080101
From basic science to blockbuster drug: the discovery of Lyrica. Angewandte Chemie (International ed. in English) 20080101
Chronic hemicorporal prurigo related to a posttraumatic Brown-Séquard syndrome. Dermatology (Basel, Switzerland) 20080101
Cost-effectiveness analysis of a lidocaine 5% medicated plaster compared with gabapentin and pregabalin for treating postherpetic neuralgia: a german perspective. Clinical drug investigation 20080101
Remission of migraine attacks in a patient with depression who is taking pregabalin. Clinical neuropharmacology 20080101
Tremor associated with chronic inflammatory demyelinating peripheral neuropathy: treatment with pregabalin. Clinical neuropharmacology 20080101
A cost-utility analysis of pregabalin in the management of peripheral neuropathic pain. Acta clinica Belgica 20080101
Effects of therapeutic doses of Pregabalin on QTc interval in conscious rabbits. European review for medical and pharmacological sciences 20080101
Pregabalin as a treatment for painful diabetic peripheral neuropathy: a meta-analysis. Regional anesthesia and pain medicine 20080101
Efficacy and safety of pregabalin 600 mg/d for treating painful diabetic peripheral neuropathy: a double-blind placebo-controlled trial. BMC neurology 20080101
Pregabalin: a review of its use in fibromyalgia. Drugs 20080101
Improvement in psoriasis following treatment with gabapentin and pregabalin. American journal of clinical dermatology 20080101
A cost-utility comparison of four first-line medications in painful diabetic neuropathy. PharmacoEconomics 20080101
Pregabalin has opioid-sparing effects following augmentation mammaplasty. Aesthetic surgery journal 20080101
[Use of anticonvulsant pregabalin as an add-on therapy in patients with partial epilepsy with polymorphic seizures]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
[Pregablin in the therapy of vertebrogenic pain syndromes in the lower back]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
Pregabalin as add-on therapy for refractory partial seizures in every day clinical practice. Seizure 20071201
Mixed effects modeling of weight change associated with placebo and pregabalin administration. Journal of pharmacokinetics and pharmacodynamics 20071201
Optimal response-adaptive designs for continuous responses in phase III trials. Biometrical journal. Biometrische Zeitschrift 20071201
Pregabalin, S-(+)-3-isobutylgaba, activates the descending noradrenergic system to alleviate neuropathic pain in the mouse partial sciatic nerve ligation model. Neuropharmacology 20071201
Efficacy and safety of pregabalin in treatment refractory patients with various neuropathic pain entities in clinical routine. International journal of clinical practice 20071201
Pregabalin in the management of central neuropathic pain. Expert opinion on pharmacotherapy 20071201
The new antiepileptic drugs. Archives of disease in childhood. Education and practice edition 20071201
Pregabalin: its pharmacology and use in pain management. Anesthesia and analgesia 20071201
Serum concentrations of pregabalin in patients with epilepsy: the influence of dose, age, and comedication. Therapeutic drug monitoring 20071201
Pregabalin: its efficacy, safety and tolerability profile in fibromyalgia syndrome. Drugs of today (Barcelona, Spain : 1998) 20071201
Clinical use of pregabalin in the management of central neuropathic pain. Neuropsychiatric disease and treatment 20071201
Pregabalin-induced generalized myoclonic status epilepticus in patients with chronic pain. Epilepsy & behavior : E&B 20071101
A randomized, placebo-controlled trial of preoperative oral pregabalin for postoperative pain relief after minor gynecological surgery. Anesthesia and analgesia 20071101
Pregabalin in the treatment of depression. Journal of psychopharmacology (Oxford, England) 20071101
Managing neuropathic pain. The Journal of the American Osteopathic Association 20071101
Pregabalin in benzodiazepine withdrawal. Pharmacopsychiatry 20071101
[Pregabalin--a neuromodulator for the treatment of neuropathic pain, generalized anxiety disorders and fibromyalgia syndrome]. Medizinische Monatsschrift fur Pharmazeuten 20071101
Fibromyalgia: understanding a mysterious ailment. The Johns Hopkins medical letter health after 50 20071101
Defensive-like behaviors induced by ultrasound: further pharmacological characterization in Lister-hooded rats. Psychopharmacology 20071001
Single-blind, placebo-controlled pilot study of pregabalin for ataxia in cortical cerebellar atrophy. Acta neurologica Scandinavica 20071001
alpha2delta ligand: a new, smart pill for visceral pain in patients with hypersensitive irritable bowel syndrome? Gut 20071001
Pregabalin decreases visceral pain and prevents spinal neuronal activation in rats. Gut 20071001
Gabapentin and pregabalin for chronic neuropathic and early postsurgical pain: current evidence and future directions. Current opinion in anaesthesiology 20071001
Pregabalin in patients with antidepressant treatment-resistant somatoform disorders: a case series. Journal of clinical psychopharmacology 20071001
Cost-effectiveness analysis of pregabalin versus gabapentin in the management of neuropathic pain due to diabetic polyneuropathy or post-herpetic neuralgia. Current medical research and opinion 20071001
Treatment of painful neuropathy. Current opinion in neurology 20071001
[Analysis of the cost-effectiveness of treatment for refractory partial epilepsy: a simulation model for pregabalin and levetiracetam]. Revista de neurologia 20071001
Pregabalin (Lyrica) for fibromyalgia. The Medical letter on drugs and therapeutics 20070924
Enantiomerically pure synthesis of beta-substituted gamma-butyrolactones: a key intermediate to concise synthesis of pregabalin. The Journal of organic chemistry 20070914
[Pregabalin in the treatment of neuropathic pain]. Nederlands tijdschrift voor geneeskunde 20070908
Effect of a second-generation alpha2delta ligand (pregabalin) on visceral sensation in hypersensitive patients with irritable bowel syndrome. Gut 20070901
Assessing the impact of pharmacologic intervention on the quality of life in diabetic peripheral neuropathic pain and fibromyalgia. Pain medicine (Malden, Mass.) 20070901
Safety profile of treatment in diabetic peripheral neuropathic pain. Pain medicine (Malden, Mass.) 20070901
Pregabalin: its efficacy, safety and tolerability profile in generalized anxiety. Drugs of today (Barcelona, Spain : 1998) 20070901
A pilot, double-blind, placebo-controlled trial of pregabalin (Lyrica) in the treatment of essential tremor. Movement disorders : official journal of the Movement Disorder Society 20070815
Exploratory polysomnographic evaluation of pregabalin on sleep disturbance in patients with epilepsy. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20070815
A cost-effectiveness comparison of desipramine, gabapentin, and pregabalin for treating postherpetic neuralgia. Journal of the American Geriatrics Society 20070801
GABAergic drugs for the treatment of migraine. CNS & neurological disorders drug targets 20070801
A retrospective evaluation of the use of gabapentin and pregabalin in patients with postherpetic neuralgia in usual-care settings. Clinical therapeutics 20070801
Practical management strategies for the chronic pain patient. The Journal of family practice 20070801
Pregabalin: an antiepileptic agent useful for neuropathic pain. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070715
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Pregabalin for the treatment of generalized anxiety disorder: a novel pharmacologic intervention. Expert review of neurotherapeutics 20070701
Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials. Pharmacopsychiatry 20070701
Pregabalin does not impact peripheral nerve regeneration after crush injury. Journal of reconstructive microsurgery 20070701
Pregabalin in central neuropathic pain associated with spinal cord injury: a placebo-controlled trial. Neurology 20070612
Alpha-2-delta ligands for singultus (hiccup) treatment: three case reports. Journal of pain and symptom management 20070601
Update on pharmacotherapy guidelines for treatment of neuropathic pain. Current pain and headache reports 20070601
Do surgical patients benefit from perioperative gabapentin/pregabalin? A systematic review of efficacy and safety. Anesthesia and analgesia 20070601
Vagoglossopharyngeal neuralgia: a rare case of sincope responding to pregabalin. Cephalalgia : an international journal of headache 20070601
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Ca2+ channel alpha2-delta ligands for the treatment of neuropathic pain. Journal of medicinal chemistry 20070531
Pregabalin reduces muscle and cutaneous hyperalgesia in two models of chronic muscle pain in rats. The journal of pain : official journal of the American Pain Society 20070501
[3H] pregabalin binding is increased in ipsilateral dorsal horn following chronic constriction injury. Neuroscience letters 20070501
Self-poisoning with lamotrigine and pregabalin. Anaesthesia 20070501
(S)-3-(Ammoniomethyl)-5-methylhexanoate (pregabalin). Acta crystallographica. Section C, Crystal structure communications 20070501
Pregabalin in restless legs syndrome with and without neuropathic pain. Acta neurologica Scandinavica 20070501
The P/Q-type voltage-dependent calcium channel: a therapeutic target in spinocerebellar ataxia type 6. Acta neurologica Scandinavica 20070501
Topical lidocaine and epidural bupivacaine/hydromorphone in the treatment of complex regional pain syndrome type 2. Pain physician 20070501
[Efficacy and tolerability of pregabalin in patients with neuropathic pain. Observational study under clinical practice conditions]. MMW Fortschritte der Medizin 20070405
Antihyperalgesic efficacy of lacosamide in a rat model for muscle pain induced by TNF. Neuropharmacology 20070401
Postoperative pain management--is there a role for gabapentin or pregabalin? Journal of perianesthesia nursing : official journal of the American Society of PeriAnesthesia Nurses 20070401
New therapies for ataxia-telangiectasia. Archives of neurology 20070401
Decompensation of chronic heart failure associated with pregabalin in patients with neuropathic pain. Journal of cardiac failure 20070401
[The 10-minute-consultation: chronic singultus]. MMW Fortschritte der Medizin 20070322
[Treatment of painful diabetic polyneuropathy. Optimizing blood glucose plus drug therapy]. MMW Fortschritte der Medizin 20070322
Pregabalin augmentation of quetiapine therapy in the treatment of fibromyalgia: an open-label, prospective trial. Pharmacopsychiatry 20070301
Postoperative pain--clinical implications of basic research. Best practice & research. Clinical anaesthesiology 20070301
Antiallodynic effect of pregabalin in rat models of sympathetically maintained and sympathetic independent neuropathic pain. Yonsei medical journal 20070227
Pharmacology and mechanism of action of pregabalin: the calcium channel alpha2-delta (alpha2-delta) subunit as a target for antiepileptic drug discovery. Epilepsy research 20070201
Effects of oral pregabalin and aprepitant on pain and central sensitization in the electrical hyperalgesia model in human volunteers. British journal of anaesthesia 20070201
Adjuvant analgesics for the treatment of neuropathic pain: evaluating efficacy and safety profiles. The Journal of family practice 20070201
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