L-Ethionine
Title | Journal |
---|---|
Discriminating between adaptive and carcinogenic liver hypertrophy in rat studies using logistic ridge regression analysis of toxicogenomic data: The mode of action and predictive models. | Toxicology and applied pharmacology 20170301 |
Genomic models of short-term exposure accurately predict long-term chemical carcinogenicity and identify putative mechanisms of action. | PloS one 20140101 |
Bmi1 is required for regeneration of the exocrine pancreas in mice. | Gastroenterology 20120901 |
Small-molecule inhibitors of the protein methyltransferase SET7/9 identified in a high-throughput screen. | Journal of biomolecular screening 20120901 |
The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat. | Experimental and molecular pathology 20120801 |
Prevention effects of ND-07, a novel drug candidate with a potent antioxidative action and anti-inflammatory action, in animal models of severe acute pancreatitis. | European journal of pharmacology 20120715 |
Identification and characterization of genes related to the production of organic acids in yeast. | Journal of bioscience and bioengineering 20120501 |
Role of bone marrow cells in the development of pancreatic fibrosis in a rat model of pancreatitis induced by a choline-deficient/ethionine-supplemented diet. | Biochemical and biophysical research communications 20120420 |
Automated annotation and quantification of metabolites in 1H NMR data of biological origin. | Analytical and bioanalytical chemistry 20120401 |
Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease. | Nature medicine 20120304 |
Importance of methionine metabolism in morula-to-blastocyst transition in bovine preimplantation embryos. | The Journal of reproduction and development 20120101 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Kupffer cells influence parenchymal invasion and phenotypic orientation, but not the proliferation, of liver progenitor cells in a murine model of liver injury. | The American journal of pathology 20111001 |
Fatty liver is associated with impaired activity of PPARγ-coactivator 1α (PGC1α) and mitochondrial biogenesis in mice. | Laboratory investigation; a journal of technical methods and pathology 20110701 |
Gas6 deficiency prevents liver inflammation, steatohepatitis, and fibrosis in mice. | American journal of physiology. Gastrointestinal and liver physiology 20110601 |
Remodelling of extracellular matrix is a requirement for the hepatic progenitor cell response. | Gut 20110401 |
New short term prediction method for chemical carcinogenicity by hepatic transcript profiling following 28-day toxicity tests in rats. | Cancer informatics 20110101 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Age dependence of oval cell responses and bile duct carcinomas in male fischer 344 rats fed a cyclic choline-deficient, ethionine-supplemented diet. | Hepatology (Baltimore, Md.) 20101101 |
Impaired liver glucose production in a murine model of steatosis and endotoxemia: protection by inducible nitric oxide synthase. | Antioxidants & redox signaling 20100701 |
Effects of acute ethionine injection on plasma ghrelin and obestatin levels in trained male rats. | Metabolism: clinical and experimental 20100701 |
Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells. | Hepatology (Baltimore, Md.) 20100701 |
Imprinting: RNA expression for homocysteine recycling in the human oocyte. | Fertility and sterility 20100315 |
Time-resolved biomarker discovery in 1H-NMR data using generalized fuzzy Hough transform alignment and parallel factor analysis. | Analytical and bioanalytical chemistry 20100301 |
A medium-term, rapid rat bioassay model for the detection of carcinogenic potential of chemicals. | Toxicologic pathology 20100101 |
Chronic pancreatitis in mice by treatment with choline-deficient ethionine-supplemented diet. | Experimental animals 20100101 |
An evaluation of the chick cardiomyocyte micromass system for identification of teratogens in a blind trial. | Reproductive toxicology (Elmsford, N.Y.) 20091201 |
Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database. | Toxicology 20091109 |
Superoxide dismutase activity as a measure of hepatic oxidative stress in cattle following ethionine administration. | Veterinary journal (London, England : 1997) 20091101 |
Ethionine-induced ATP depletion represses mTOR signaling in the absence of increases in AMP-activated protein kinase activity in the rat liver. | Bioscience, biotechnology, and biochemistry 20090901 |
Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy. | The Journal of toxicological sciences 20090601 |
Separation and determination of seleno amino acids using gas chromatography hyphenated with inductively coupled plasma mass spectrometry after hollow fiber liquid phase microextraction. | Journal of mass spectrometry : JMS 20090501 |
Relation between liver progenitor cell expansion and extracellular matrix deposition in a CDE-induced murine model of chronic liver injury. | Hepatology (Baltimore, Md.) 20090501 |
Expression of extracellular matrix genes in cultured hepatic oval cells: an origin of hepatic stellate cells through transforming growth factor beta? | Liver international : official journal of the International Association for the Study of the Liver 20090401 |
Risperidone attenuates local and systemic inflammatory responses to ameliorate diet-induced severe necrotic pancreatitis in mice: it may provide a new therapy for acute pancreatitis. | The Journal of pharmacology and experimental therapeutics 20090101 |
Lymphotoxin-beta receptor signaling regulates hepatic stellate cell function and wound healing in a murine model of chronic liver injury. | Hepatology (Baltimore, Md.) 20090101 |
Ginger extract (Zingiber officinale) has anti-cancer and anti-inflammatory effects on ethionine-induced hepatoma rats. | Clinics (Sao Paulo, Brazil) 20081201 |
C-kit inhibition by imatinib mesylate attenuates progenitor cell expansion and inhibits liver tumor formation in mice. | Gastroenterology 20080901 |
Bone marrow cells play only a very minor role in chronic liver regeneration induced by a choline-deficient, ethionine-supplemented diet. | Stem cell research 20080901 |
Total glutathione and glutathione reductase in bovine erythrocytes and liver biopsy. | The Journal of veterinary medical science 20080801 |
X-ray structure of the [FeFe]-hydrogenase maturase HydE from Thermotoga maritima. | The Journal of biological chemistry 20080704 |
Random mutagenesis and recombination of sam1 gene by integrating error-prone PCR with staggered extension process. | Biotechnology letters 20080701 |
Bone marrow-derived cells fuse with hepatic oval cells but are not involved in hepatic tumorigenesis in the choline-deficient ethionine-supplemented diet rat model. | Carcinogenesis 20080201 |
Misincorporation of amino acid analogues into proteins by biosynthesis. | The international journal of biochemistry & cell biology 20080101 |
Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice. | Laboratory investigation; a journal of technical methods and pathology 20071201 |
Analysis of time-related metabolic fluctuations induced by ethionine in the rat. | Journal of proteome research 20071201 |
The Birt-Hogg-Dube and tuberous sclerosis complex homologs have opposing roles in amino acid homeostasis in Schizosaccharomyces pombe. | The Journal of biological chemistry 20070824 |
Therapeutic treatment with poly(ADP-ribose) polymerase inhibitors attenuates the severity of acute pancreatitis and associated liver and lung injury. | British journal of pharmacology 20070801 |
6His-Eco29kI methyltransferase methylation site and kinetic mechanism characterization. | Biochimica et biophysica acta 20070801 |
Characteristics of methionine production by an engineered Corynebacterium glutamicum strain. | Metabolic engineering 20070701 |
Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells. | Hepatology research : the official journal of the Japan Society of Hepatology 20070501 |
Hepatotoxin-induced hypertyrosinemia and its toxicological significance. | Archives of toxicology 20070301 |
Functional characterization of a methionine gamma-lyase in Arabidopsis and its implication in an alternative to the reverse trans-sulfuration pathway. | Plant & cell physiology 20070201 |
Different effects of sulfur amino acids on prolidase and prolinase activity in normal and prolidase-deficient human erythrocytes. | Clinica chimica acta; international journal of clinical chemistry 20070101 |
Attenuated liver progenitor (oval) cell and fibrogenic responses to the choline deficient, ethionine supplemented diet in the BALB/c inbred strain of mice. | Journal of hepatology 20070101 |
Isolation, culture and immortalisation of hepatic oval cells from adult mice fed a choline-deficient, ethionine-supplemented diet. | The international journal of biochemistry & cell biology 20070101 |
An unusual S-adenosylmethionine synthetase gene from dinoflagellate is methylated. | BMC molecular biology 20070101 |
Activation of nuclear factor kappa B and severe hepatic necrosis may mediate systemic inflammation in choline-deficient/ethionine-supplemented diet-induced pancreatitis. | Pancreas 20061001 |
Hepatic oval cell response to the choline-deficient, ethionine supplemented model of murine liver injury is attenuated by the administration of a cyclo-oxygenase 2 inhibitor. | Carcinogenesis 20060801 |
Integrity of the methylation cycle is essential for mammalian neural tube closure. | Birth defects research. Part A, Clinical and molecular teratology 20060701 |
Natural and directed biosynthesis of communesin alkaloids. | Phytochemistry 20060301 |
Structure-activity relationships of alpha-amino acid ligands for the alpha2delta subunit of voltage-gated calcium channels. | Bioorganic & medicinal chemistry letters 20060301 |
Effect of amino acids containing sulfur on dithiolopyrrolone antibiotic productions by Saccharothrix algeriensis NRRL B-24137. | Journal of applied microbiology 20060201 |
S-adenosyl methionine: A connection between nutritional and genetic risk factors for neurodegeneration in Alzheimer's disease. | The journal of nutrition, health & aging 20060101 |
Harnessing natural diversity to probe metabolic pathways. | PLoS genetics 20051201 |
Effects of R-102444 and its active metabolite R-96544, selective 5-HT2A receptor antagonists, on experimental acute and chronic pancreatitis: Additional evidence for possible involvement of 5-HT2A receptors in the development of experimental pancreatitis. | European journal of pharmacology 20051003 |
Inhibition of adult liver progenitor (oval) cell growth and viability by an agonist of the peroxisome proliferator activated receptor (PPAR) family member gamma, but not alpha or delta. | Carcinogenesis 20051001 |
Regional differences in gastrointestinal motility disturbances during acute necrotising pancreatitis. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20051001 |
Single-gene knockout of a novel regulatory element confers ethionine resistance and elevates methionine production in Corynebacterium glutamicum. | Applied microbiology and biotechnology 20050801 |
Liver inflammation and cytokine production, but not acute phase protein synthesis, accompany the adult liver progenitor (oval) cell response to chronic liver injury. | Immunology and cell biology 20050801 |
Natural disruption of group 2 phospholipase A2 gene protects against choline-deficient ethionine-supplemented diet-induced acute pancreatitis and lung injury. | Pancreas 20050701 |
Oncostatin M induces an acute phase response but does not modulate the growth or maturation-status of liver progenitor (oval) cells in culture. | Experimental cell research 20050515 |
Differential lymphotoxin-beta and interferon gamma signaling during mouse liver regeneration induced by chronic and acute injury. | Hepatology (Baltimore, Md.) 20050201 |
TNF/LTalpha double knockout mice display abnormal inflammatory and regenerative responses to acute and chronic liver injury. | Cell and tissue research 20050101 |
In vivo antihepatotoxic effects of Ligularia fischeri var. spiciformis and the identification of the active component, 3,4-dicaffeoylquinic acid. | Journal of medicinal food 20050101 |
Selection and characterization of L-ethionine resistant mutants of Trichosporon cutaneum. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101 |
Ablation of phosphoinositide 3-kinase-gamma reduces the severity of acute pancreatitis. | The American journal of pathology 20041201 |
[Animal experimental models for acute pancreatitis]. | Nihon rinsho. Japanese journal of clinical medicine 20041101 |
Decreases in serum apolipoprotein C-III concentration in cows with ethionine-induced fatty liver. | The Journal of veterinary medical science 20040901 |
Suppression of 8-oxo-2'-deoxyguanosine formation and carcinogenesis induced by N-nitrosobis (2-oxopropyl)amine in hamsters by esculetin and esculin. | Free radical research 20040801 |
Protective effect of soybean against hepatocarcinogenesis induced by DL-ethionine. | Journal of biochemistry and molecular biology 20040531 |
Gene expression profiles in liver regeneration with oval cell induction. | Biochemical and biophysical research communications 20040430 |
Activation, isolation, identification and in vitro proliferation of oval cells from adult rat livers. | Cell proliferation 20040401 |
Organ-specific stress induces mouse pancreatic keratin overexpression in association with NF-kappaB activation. | Journal of cell science 20040401 |
Direct effects of interleukin-6 on liver progenitor oval cells in culture. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20040101 |
Enhancement of the primary flavor compound methional in potato by increasing the level of soluble methionine. | Journal of agricultural and food chemistry 20030910 |
Cellular proliferation in the canine pancreas after d,l-ethionine dosage as detected by double immunohistochemical labelling. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030901 |
S-adenosylmethionine (AdoMet) modulates endotoxin stimulated interleukin-10 production in monocytes. | American journal of physiology. Gastrointestinal and liver physiology 20030601 |
Physiologically relevant metal cofactor for methionine aminopeptidase-2 is manganese. | Biochemistry 20030506 |
An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria. | Archives of toxicology 20030401 |
Macrophage migration inhibitory factor is a critical mediator of severe acute pancreatitis. | Gastroenterology 20030301 |
Diminished lung injury with vascular adhesion molecule-1 blockade in choline-deficient ethionine diet-induced pancreatitis. | Surgery 20030201 |
Pancreatic concentrations of cefepime in experimental necrotizing pancreatitis. | Journal of chemotherapy (Florence, Italy) 20030201 |
Role of S-adenosylmethionine in two experimental models of pancreatitis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030101 |
Effect of IS-741 on ethionine-induced acute pancreatitis in rats: relation to pancreatic acinar cell regeneration. | Journal of gastroenterology 20030101 |
Pancreatic regeneration after ethionine-induced acute pancreatitis in rats lacking pancreatic CCK-A receptor gene expression. | Journal of gastroenterology 20030101 |
Translational initiation regulators are hypophosphorylated in rat liver during ethionine-mediated ATP depletion. | Biochemical and biophysical research communications 20021025 |
Ethanol interactions with a choline-deficient, ethionine-supplemented feeding regime potentiate pre-neoplastic cellular alterations in rat liver. | Carcinogenesis 20021001 |
Identification of a short highly conserved amino acid sequence as the functional region required for posttranscriptional autoregulation of the cystathionine gamma-synthase gene in Arabidopsis. | The Journal of biological chemistry 20020927 |
Isolation, cloning and expression of a multifunctional O-methyltransferase capable of forming 2,5-dimethyl-4-methoxy-3(2H)-furanone, one of the key aroma compounds in strawberry fruits. | The Plant journal : for cell and molecular biology 20020901 |
Effect of d,l-ethionine administration on the histomorphology of canine pancreatic acinar and beta-cells. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020801 |
A single-nucleotide mutation in a gene encoding S-adenosylmethionine synthetase is associated with methionine over-accumulation phenotype in Arabidopsis thaliana. | Genes & genetic systems 20020401 |
Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma. | Carcinogenesis 20020301 |
Protein repair methyltransferase from the hyperthermophilic archaeon Pyrococcus furiosus. Unusual methyl-accepting affinity for D-aspartyl and N-succinyl-containing peptides. | The Journal of biological chemistry 20020111 |
Constitutive overexpression of cystathionine gamma-synthase in Arabidopsis leads to accumulation of soluble methionine and S-methylmethionine. | Plant physiology 20020101 |
Evaluation of d,l-ethionine as a mechanism for pancreatic islet regeneration in dogs. | Australian veterinary journal 20020101 |
Methionine depletion induces transcription of the mRNA (N6-adenosine)methyltransferase. | The international journal of biochemistry & cell biology 20011101 |
Methylation is involved in the Ustilago maydis mating response. | Fungal genetics and biology : FG & B 20011001 |
A modified choline-deficient, ethionine-supplemented diet protocol effectively induces oval cells in mouse liver. | Hepatology (Baltimore, Md.) 20010901 |
Adenoviral delivery of human and viral IL-10 in murine sepsis. | Journal of immunology (Baltimore, Md. : 1950) 20010715 |
Biosynthesis of diaporthin and orthosporin by Aspergillus ochraceus. | Phytochemistry 20010501 |
Evaluation of lysine and methionine production in some Lactobacilli and yeasts from ogi. | International journal of food microbiology 20010122 |
Methionine deprivation and methionine analogs inhibit cell proliferation and growth of human xenografted gliomas. | Life sciences 19970101 |
13-cis-retinoic acid and hepatic steatosis in rats. | Biochemical pharmacology 19930720 |
Effects of the seleno-organic substance Ebselen in two different models of acute pancreatitis. | Pancreas 19910501 |
Correlation between medium-term liver bioassay system data and results of long-term testing in rats. | Carcinogenesis 19900401 |
Hepatic levels of cytosolic, microsomal and 'mitochondrial' epoxide hydrolases and other drug-metabolizing enzymes after treatment of mice with various xenobiotics and endogenous compounds. | Chemico-biological interactions 19870101 |
Comparison of the promoting effects of various agents in induction of preneoplastic lesions in rat liver. | Environmental health perspectives 19830401 |
Increased alpha1-fetoprotein production in rat liver injuries induced by various hepatotoxins. | Gan 19760401 |