Protopine
Title | Journal |
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A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain. | Journal of ethnopharmacology 20131212 |
Genetic and chemical components analysis of Papaver setigerum naturalized in Korea. | Forensic science international 20121010 |
Design and evaluation of self-emulsifying drug delivery systems of Rhizoma corydalis decumbentis extracts. | Drug development and industrial pharmacy 20121001 |
Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia. | Journal of ethnopharmacology 20120830 |
[Study on absorption ingredients of yuanhuzhitong pill by everted intestinal sac method]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120701 |
Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa. | Natural product communications 20120501 |
Induction of heme oxygenase-1 by Macleaya cordata extract and its constituent sanguinarine in RAW264.7 cells. | Fitoterapia 20120301 |
Rapid discrimination and quantification of alkaloids in Corydalis Tuber by near-infrared spectroscopy. | Journal of pharmaceutical and biomedical analysis 20120205 |
Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines. | Cancer letters 20120201 |
Protopine reduces the inflammatory activity of lipopolysaccharide-stimulated murine macrophages. | BMB reports 20120201 |
Effect of wine and vinegar processing of Rhizoma Corydalis on the tissue distribution of tetrahydropalmatine, protopine and dehydrocorydaline in rats. | Molecules (Basel, Switzerland) 20120118 |
Alkaloids and flavonoids of Argemone mexicana. | Natural product research 20120101 |
Species and tissue-specificity of prokinetic, laxative and spasmodic effects of Fumaria parviflora. | BMC complementary and alternative medicine 20120101 |
Inhibitory Effect of Ginsenoside Rg1 on Vascular Smooth Muscle Cell Proliferation Induced by PDGF-BB Is Involved in Nitric Oxide Formation. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Isocorydine inhibits cell proliferation in hepatocellular carcinoma cell lines by inducing G2/m cell cycle arrest and apoptosis. | PloS one 20120101 |
[Chemical constituents from Corydalis yanhusuo]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120101 |
CYP2C19 progress curve analysis and mechanism-based inactivation by three methylenedioxyphenyl compounds. | Drug metabolism and disposition: the biological fate of chemicals 20111201 |
Alkaloids from Chelidonium majus and their inhibitory effects on LPS-induced NO production in RAW264.7 cells. | Bioorganic & medicinal chemistry letters 20111201 |
Preparative isolation of alkaloids from Dactylicapnos scandens using pH-zone-refining counter-current chromatography by changing the length of the separation column. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111201 |
Simultaneous quantification of 17 constituents from Yuanhu Zhitong tablet using rapid resolution liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20111101 |
Alkaloids from Papaver coreanum. | Natural product communications 20111101 |
Acetylcholinesterase inhibitors from Corydalis yanhusuo. | Natural product research 20110901 |
Biocatalytic organic synthesis of optically pure (S)-scoulerine and berbine and benzylisoquinoline alkaloids. | The Journal of organic chemistry 20110819 |
Capillary electrophoresis with LED-induced native fluorescence detection for determination of isoquinoline alkaloids and their cytotoxicity in extracts of Chelidonium majus L. | Journal of chromatography. A 20110805 |
Identification of a novel bacterial K(+) channel. | The Journal of membrane biology 20110801 |
[Determination of four alkaloids in Corydalis decumbens by HPLC]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110801 |
Protopine and allocryptopine increase mRNA levels of cytochromes P450 1A in human hepatocytes and HepG2 cells independently of AhR. | Toxicology letters 20110610 |
Chemical study and anti-inflammatory, analgesic and antioxidant activities of the leaves of Aristotelia chilensis (Mol.) Stuntz, Elaeocarpaceae. | The Journal of pharmacy and pharmacology 20110601 |
Preparative isolation of alkaloids from Corydalis bungeana Turcz. by high-speed counter-current chromatography using stepwise elution. | Journal of separation science 20110501 |
Seasonal variation of bioactive alkaloid contents in Macleaya microcarpa (Maxim.) Fedde. | Molecules (Basel, Switzerland) 20110420 |
[Simultaneous determination of four alkaloids in Corydalis decumbens (Thunb.) Pers. by high performance liquid chromatography-tandem mass spectrometry]. | Se pu = Chinese journal of chromatography 20110201 |
A 'reverse pharmacology' approach for developing an anti-malarial phytomedicine. | Malaria journal 20110101 |
Phytochemical and antimicrobial characterization of Macleaya cordata herb. | Fitoterapia 20101201 |
Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Chelidonium majus (Papaveraceae). | Natural product communications 20101101 |
Extractions of isoquinoline alkaloids with butanol and octanol. | Fitoterapia 20100901 |
[Determination of protopine in Corydalis racemose by HPLC]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20100901 |
In vivo anthelmintic activity of five alkaloids from Macleaya microcarpa (Maxim) Fedde against Dactylogyrus intermedius in Carassius auratus. | Veterinary parasitology 20100804 |
A study on separation and extraction of four main alkaloids in Macleaya cordata (Willd) R. Br. with strip dispersion hybrid liquid membrane. | Journal of separation science 20100701 |
Optimization of microwave-assisted extraction of protopine and allocryptopine from stems of Macleaya cordata (Willd) R. Br. using response surface methodology. | Journal of separation science 20100701 |
Validated liquid chromatography-tandem mass spectrometry method for quantitative determination of dauricine in human plasma and its application to pharmacokinetic study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100501 |
Antiplasmodial agents from the Bhutanese medicinal plant Corydalis calliantha. | Phytotherapy research : PTR 20100401 |
Simultaneous determination of seven main alkaloids of Chelidonium majus L. by ultra-performance LC with photodiode-array detection. | Journal of separation science 20100401 |
Screening of antinociceptive components in Corydalis yanhusuo W.T. Wang by comprehensive two-dimensional liquid chromatography/tandem mass spectrometry. | Analytical and bioanalytical chemistry 20100301 |
BIAdb: a curated database of benzylisoquinoline alkaloids. | BMC pharmacology 20100101 |
Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures. | BMC plant biology 20100101 |
Isoquinoline alkaloids from Macleaya cordata active against plant microbial pathogens. | Natural product communications 20091101 |
Electron ionisation mass spectral study of 2-(2-carboxy-4, 5-dimethoxyphenyl)-6,7-dimethoxyisoquinolinium inner salt. | Die Pharmazie 20091101 |
[Alkaloids from Dactylicapnos scandens Hutch]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090801 |
[Alkaloids from Macleaya cordata]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090701 |
Analysis of alkaloids in Macleaya cordata (Willd.) R. Br. using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry. | Journal of chromatography. A 20090313 |
Simultaneous determination of tetrahydropalmatine, protopine, and palmatine in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study. | Journal of pharmaceutical and biomedical analysis 20090220 |
Alkaloids from Mongolian species Hypecoum lactiflorum Kar. et Kir. Pazij. | Natural product research 20090101 |
Identification and characterization of a dual-acting antinematodal agent against the pinewood nematode, Bursaphelenchus xylophilus. | PloS one 20090101 |
Protective effects of protopine on hydrogen peroxide-induced oxidative injury of PC12 cells via Ca(2+) antagonism and antioxidant mechanisms. | European journal of pharmacology 20080904 |
Hepatoprotective potential of Fumaria indica Pugsley whole plant extracts, fractions and an isolated alkaloid protopine. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20080601 |
Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures. | BMC plant biology 20080101 |
Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts. | Phytochemical analysis : PCA 20080101 |
On the synthesis of protopine alkaloids. | The Journal of organic chemistry 20070914 |
Conventional sample enrichment strategies combined with high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance analysis allows analyte identification from a single minuscule Corydalis solida plant tuber. | Journal of chromatography. A 20070907 |
Protective effect of protopine on the focal cerebral ischaemic injury in rats. | Basic & clinical pharmacology & toxicology 20070801 |
Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy. | The Journal of biological chemistry 20070518 |
Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism. | Planta 20070401 |
Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding. | Phytochemistry 20070101 |
Antiviral and antimicrobial profiles of selected isoquinoline alkaloids from Fumaria and Corydalis species. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101 |
Effect of isoquinoline alkaloids of different structural types on antiplatelet aggregation in vitro. | Planta medica 20061001 |
Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models. | Neuropharmacology 20060601 |
Large-scale separation of alkaloids from Corydalis decumbens by pH-zone-refining counter-current chromatography. | Journal of chromatography. A 20060519 |
Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. | Journal of natural products 20060301 |
Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway. | BMC cancer 20060101 |
Intestinal spasmolytic effects of STW 5 (Iberogast) and its components. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20060101 |
Rapid determination of protopine, allocryptopine, sanguinarine and chelerythrine in fruits of Macleaya cordata by microwave-assisted solvent extraction and HPLC-ESI/MS. | Phytochemical analysis : PCA 20060101 |
Regulation of glutamate level in rat brain through activation of glutamate dehydrogenase by Corydalis ternata. | Experimental & molecular medicine 20050831 |
Theoretical and experimental NMR study of protopine hydrochloride isomers. | Magnetic resonance in chemistry : MRC 20050701 |
Effects of protopine on intracellular calcium and the PKC activity of rat aorta smooth muscle. | Sheng li xue bao : [Acta physiologica Sinica] 20050425 |
Effect of binary combination of some plant-derived molluscicides with MGK-264 or piperonyl butoxide on the reproduction of the snail Lymnaea acuminata. | Pest management science 20050201 |
[Studies on the alkaloids from the herb of Corydalis adunca]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050201 |
Identification and quantification of isoquinoline alkaloids in the genus Sarcocapnos by GC-MS. | Phytochemical analysis : PCA 20050101 |
Inhibitory effect of protopine on K(ATP) channel subunits expressed in HEK-293 cells. | European journal of pharmacology 20041215 |
Protopine alkaloids in horse urine. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041105 |
Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. | Archives of pharmacal research 20041101 |
1H and 13C NMR signal assignment of benzylisoquinoline alkaloids from Fumaria officinalis L. (Papaveraceae). | Magnetic resonance in chemistry : MRC 20041001 |
[Determination of protopine and isocorydine in root of Dactylicapnos scandens by HPLC]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20041001 |
How to treat tremor. | Journal of neurology 20040501 |
Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. | European journal of pharmacology 20040206 |
Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids. | Toxicology letters 20031215 |
Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum. | Fitoterapia 20030701 |
Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030605 |
In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis. | Phytotherapy research : PTR 20030301 |
Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyldihydrochelerythrine from formosan Argemone mexicana. | Planta medica 20030201 |
In vitro anti-influenza virus activity of isoquinoline alkaloids from thalictrum species. | Planta medica 20030201 |
Cytotoxic activity and quality control determinations on Chelidonium majus. | Fitoterapia 20030201 |
Assay of nematocidal activity of isoquinoline alkaloids using third-stage larvae of Strongyloides ratti and S. venezuelensis. | Veterinary parasitology 20020301 |
Direct determination of alkaloid contents in Fumaria species by GC-MS. | Phytochemical analysis : PCA 20020101 |
[RP-HPLC method for determination of protopine in plasma and pharmacokinetics in rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20011001 |
Elevational trends in defense chemistry, vegetation, and reproduction in Sanguinaria canadensis. | Journal of chemical ecology 20010901 |
A new tetrahydroprotoberberine N-oxide alkaloid and anti-platelet aggregation constituents of Corydalis tashiroi. | Planta medica 20010701 |
Protopine hydrochloride. | Acta crystallographica. Section C, Crystal structure communications 20010501 |