Home Other Building Blocks 1,4-Naphthoquinone

1,4-Naphthoquinone

CAS No.:
130-15-4
Catalog Number:
AG000TUS
Molecular Formula:
C10H6O2
Molecular Weight:
158.1534
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%(GC)
In Stock USA
United States
$41
- +
25g
98%(GC)
In Stock USA
United States
$60
- +
100g
98%(GC)
In Stock USA
United States
$111
- +
500g
98%(GC)
In Stock USA
United States
$311
- +
Product Description
Catalog Number:
AG000TUS
Chemical Name:
1,4-Naphthoquinone
CAS Number:
130-15-4
Molecular Formula:
C10H6O2
Molecular Weight:
158.1534
MDL Number:
MFCD00001676
IUPAC Name:
naphthalene-1,4-dione
InChI:
InChI=1S/C10H6O2/c11-9-5-6-10(12)8-4-2-1-3-7(8)9/h1-6H
InChI Key:
FRASJONUBLZVQX-UHFFFAOYSA-N
SMILES:
O=C1C=CC(=O)c2c1cccc2
EC Number:
204-977-6
UNII:
RBF5ZU7R7K
NSC Number:
9583
RTECS Number:
QL7175000
Properties
Complexity:
227  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
158.037g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
158.156g/mol
Monoisotopic Mass:
158.037g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
34.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.7  
Literature
Title Journal
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Singlet oxygen production by pyrano and furano 1,4-naphthoquinones in non-aqueous medium. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120701
A heptaketide naphthaldehyde produced by a polyketide synthase from Nectria haematococca. Bioorganic & medicinal chemistry letters 20120701
Exploring the trifluoromenadione core as a template to design antimalarial redox-active agents interacting with glutathione reductase. Organic & biomolecular chemistry 20120628
Langkolide, a 32-membered macrolactone antibiotic produced by Streptomyces sp. Acta 3062. Journal of natural products 20120622
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Antibacterial and antifungal activity of lawsone and novel naphthoquinone derivatives. Medecine et maladies infectieuses 20120601
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A new type of pterocarpanquinone that affects Toxoplasma gondii tachyzoites in vitro. Veterinary parasitology 20120525
Identification of novel liver X receptor activators by structure-based modeling. Journal of chemical information and modeling 20120525
Cytotoxic and antioxidant marine prenylated quinones and hydroquinones. Natural product reports 20120501
Study on cytotoxicity and structure-activity relationship of HL-7702 cell exposed to naphthoquinones. Environmental toxicology and pharmacology 20120501
Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. European journal of medicinal chemistry 20120501
Menaquinone-7 is specific cofactor in tetraheme quinol dehydrogenase CymA. The Journal of biological chemistry 20120420
Design and synthesis of naphthoquinone derivatives as antiproliferative agents and 20S proteasome inhibitors. Bioorganic & medicinal chemistry letters 20120415
Mechanism of inhibition of the ATPase domain of human topoisomerase IIα by 1,4-benzoquinone, 1,2-naphthoquinone, 1,4-naphthoquinone, and 9,10-phenanthroquinone. Toxicological sciences : an official journal of the Society of Toxicology 20120401
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High conservatism in the composition of scent gland secretions in cyphophthalmid harvestmen: evidence from pettalidae. Journal of chemical ecology 20120401
Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression. The Journal of biological chemistry 20120323
Synergistic TRAIL sensitizers from Barleria alluaudii and Diospyros maritima. Journal of natural products 20120323
Library synthesis and antibacterial investigation of cationic anthraquinone analogs. ACS combinatorial science 20120312
Hydroxyl radical generation mechanism during the redox cycling process of 1,4-naphthoquinone. Environmental science & technology 20120306
First synthesis and anticancer activity of novel naphthoquinone amides. European journal of medicinal chemistry 20120301
Selective and slow-binding inhibition of shikonin derivatives isolated from Lithospermum erythrorhizon on glycosyl hydrolase 33 and 34 sialidases. Bioorganic & medicinal chemistry 20120301
A novel class of small molecule inhibitors of HDAC6. ACS chemical biology 20120217
Luciferase inhibition by a novel naphthoquinone. Journal of photochemistry and photobiology. B, Biology 20120206
Linking oxidative events to inflammatory and adaptive gene expression induced by exposure to an organic particulate matter component. Environmental health perspectives 20120201
Plumbagin inhibits cell growth and potentiates apoptosis in human gastric cancer cells in vitro through the NF-κB signaling pathway. Acta pharmacologica Sinica 20120201
Synthetic strategies to terpene quinones/hydroquinones. Marine drugs 20120201
Induction of apoptosis in HL-60 cells through the ROS-mediated mitochondrial pathway by ramentaceone from Drosera aliciae. Journal of natural products 20120127
Copper(II)-catalyzed synthesis of benzo[f]pyrido[1,2-a]indole-6,11-dione derivatives via naphthoquinone difunctionalization reaction. The Journal of organic chemistry 20120120
5'-monohydroxyphylloquinone is the dominant naphthoquinone of PSI in the green alga Chlamydomonas reinhardtii. Plant & cell physiology 20120101
Reviews on 1,4-naphthoquinones from Diospyros L. Journal of Asian natural products research 20120101
Antitrypanosomal activities and cytotoxicity of some novel imido-substituted 1,4-naphthoquinone derivatives. Archives of pharmacal research 20120101
Vitamin K supplementation does not prevent bone loss in ovariectomized Norway rats. Nutrition & metabolism 20120101
New 2-aryl-1,4-naphthoquinone-1-oxime methyl ether compound induces microtubule depolymerization and subsequent apoptosis. Journal of pharmacological sciences 20120101
Validation of the Antiproliferative Effects of Organic Extracts from the Green Husk of Juglans regia L. on PC-3 Human Prostate Cancer Cells by Assessment of Apoptosis-Related Genes. Evidence-based complementary and alternative medicine : eCAM 20120101
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Gossypol Inhibits Electron Transport and Stimulates ROS Generation in Yarrowia lipolytica Mitochondria. The open biochemistry journal 20120101
Rhinacanthus nasutus extracts prevent glutamate and amyloid-β neurotoxicity in HT-22 mouse hippocampal cells: possible active compounds include lupeol, stigmasterol and β-sitosterol. International journal of molecular sciences 20120101
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Characterization of model peptide adducts with reactive metabolites of naphthalene by mass spectrometry. PloS one 20120101
Identification of naphthalene metabolism by white rot fungus Armillaria sp. F022. Journal of environmental sciences (China) 20120101
Organocatalytic asymmetric Michael addition of unprotected 3-substituted oxindoles to 1,4-naphthoquinone. Beilstein journal of organic chemistry 20120101
A method for detecting covalent modification of sensor proteins associated with 1,4-naphthoquinone-induced activation of electrophilic signal transduction pathways. The Journal of toxicological sciences 20120101
Shikonin directly targets mitochondria and causes mitochondrial dysfunction in cancer cells. Evidence-based complementary and alternative medicine : eCAM 20120101
Lapachol as an epithelial tumor inhibitor agent in Drosophila melanogaster heterozygote for tumor suppressor gene wts. Genetics and molecular research : GMR 20111222
Lateral extension of π conjugation along the bay regions of bisanthene through a Diels-Alder cycloaddition reaction. Chemistry (Weinheim an der Bergstrasse, Germany) 20111216
Shikonin, a Chinese plant-derived naphthoquinone, induces apoptosis in hepatocellular carcinoma cells through reactive oxygen species: A potential new treatment for hepatocellular carcinoma. Free radical biology & medicine 20111215
Generation of reactive oxygen species mediated by humic-like substances in atmospheric aerosols. Environmental science & technology 20111215
Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO. Bioorganic & medicinal chemistry 20111215
NMR studies reveal an unexpected binding site for a redox inhibitor of AP endonuclease 1. Biochemistry 20111206
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Structure/antileishmanial activity relationship study of naphthoquinones and dependency of the mode of action on the substitution patterns. Planta medica 20111201
Inhibitory effects of vitamin K₃ derivatives on DNA polymerase and inflammatory activity. International journal of molecular medicine 20111201
The 1,4-naphthoquinone derivative from Pyrola rotundifolia activates AMPK phosphorylation in C2C12 myotubes. Fitoterapia 20111201
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Application of the atoms in molecules theory and computational chemistry in mass spectrometry analysis of 1,4-naphthoquinone derivatives. The journal of physical chemistry. A 20111117
Method development for the measurement of quinone levels in urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111115
In vitro cultures of Drosera aliciae as a source of a cytotoxic naphthoquinone: ramentaceone. Biotechnology letters 20111101
Induction of cell death by a novel naphthoquinone containing a modified anthracycline ring system. Chemical biology & drug design 20111101
Distribution of naphthoquinones, plumbagin, droserone, and 5-O-methyl droserone in chitin-induced and uninduced Nepenthes khasiana: molecular events in prey capture. Journal of experimental botany 20111101
Micelles catalyzed chemoselective synthesis 'in water' and biological evaluation of oxygen containing hetero-1,4-naphthoquinones as potential antifungal agents. Bioorganic & medicinal chemistry letters 20111101
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Studies on filarial GST as a target for antifilarial drug development-in silico and in vitro inhibition of filarial GST by substituted 1,4-naphthoquinones. Journal of molecular modeling 20111001
Inhibitory effect of novel 5-O-acyl juglones on mammalian DNA polymerase activity, cancer cell growth and inflammatory response. Bioorganic & medicinal chemistry 20111001
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Synthesis and anti-Trypanosoma cruzi activity of β-lapachone analogues. European journal of medicinal chemistry 20110701
Pro-oxidants ameliorate radiation-induced apoptosis through activation of the calcium-ERK1/2-Nrf2 pathway. Free radical biology & medicine 20110701
Effectiveness of the local or oral delivery of the novel naphthopterocarpanquinone LQB-118 against cutaneous leishmaniasis. The Journal of antimicrobial chemotherapy 20110701
C-H functionalization of 1,4-naphthoquinone by oxidative coupling with anilines in the presence of a catalytic quantity of copper(II) acetate. The Journal of organic chemistry 20110701
Study on acute toxicity and structure-activity relationship of Daphnia magna exposed to naphthoquinones. Environmental toxicology and pharmacology 20110701
Topoisomerase I inactivation by a novel thiol reactive naphthoquinone. Biochemical and biophysical research communications 20110624
Generation of naphthoquinone radical anions by electrospray ionization: solution, gas-phase, and computational chemistry studies. The journal of physical chemistry. A 20110602
Metabolism of a dopamine receptor partial agonist in rats, including an unusual N-dearylation reaction. Drug metabolism and pharmacokinetics 20110601
Topoisomerase I/II inhibition by a novel naphthoquinone containing a modified anthracycline ring system. Biochemical and biophysical research communications 20110429
NP-313, 2-acetylamino-3-chloro-1,4-naphthoquinone, a novel antithrombotic agent with dual inhibition of thromboxane A(2) synthesis and calcium entry. British journal of pharmacology 20110401
The pea SAD short-chain dehydrogenase/reductase: quinone reduction, tissue distribution, and heterologous expression. Plant physiology 20110401
Involvement of thermoplasmaquinone-7 in transplasma membrane electron transport of Entamoeba histolytica trophozoites: a key molecule for future rational chemotherapeutic drug designing. Journal of bioenergetics and biomembranes 20110401
2-Meth-oxy-naphthalene-1,4-dione. Acta crystallographica. Section E, Structure reports online 20110401
Reaction of the molybdenum- and copper-containing carbon monoxide dehydrogenase from Oligotropha carboxydovorans with quinones. Biochemistry 20110322
Antiviral agents 3. Discovery of a novel small molecule non-nucleoside inhibitor of hepatitis B virus (HBV). Bioorganic & medicinal chemistry letters 20110315
A prototype hybrid 7π quinone-fused 1,3,2-dithiazolyl radical. Dalton transactions (Cambridge, England : 2003) 20110128
Direct photooxidation and xanthene-sensitized oxidation of naphthols: quantum yields and mechanism. The journal of physical chemistry. A 20110127
Synthesis of 1,4-naphthoquinone methides via acid-catalyzed cascade cyclizations of benzannulated enediynyl alcohols. Organic letters 20110107
In Vitro Activity of 2-methoxy-1,4-naphthoquinone and Stigmasta-7,22-diene-3β-ol from Impatiens balsamina L. against Multiple Antibiotic-Resistant Helicobacter pylori. Evidence-based complementary and alternative medicine : eCAM 20110101
Trypanosoma cruzi: insights into naphthoquinone effects on growth and proteinase activity. Experimental parasitology 20110101
Synthesis and antibacterial activity study of a novel class of cationic anthraquinone analogs. Bioorganic & medicinal chemistry 20110101
Tigloylshikonin, a new minor Shikonin derivative, from the roots and the commercial root extract of lithospermum erythrorhizon. Chemical & pharmaceutical bulletin 20110101
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2-Aryl-1,4-naphthoquinone-1-oxime methyl ethers: their cytotoxic activity. Chemical & pharmaceutical bulletin 20110101
Exploiting the high-resolution crystal structure of Staphylococcus aureus MenH to gain insight into enzyme activity. BMC structural biology 20110101
Effects of intermediates between vitamins K(2) and K(3) on mammalian DNA polymerase inhibition and anti-inflammatory activity. International journal of molecular sciences 20110101
Synthesis of biologically active (-)-dehydroiso-β-lapachone and the determination of its absolute configuration. Chemical & pharmaceutical bulletin 20110101
Screening of Potential anti-Trypanosoma cruzi Candidates: In Vitro and In Vivo Studies. The open medicinal chemistry journal 20110101
Synergistic antimicrobial activity between pentacyclic triterpenoids and antibiotics against Staphylococcus aureus strains. Annals of clinical microbiology and antimicrobials 20110101
Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus. Marine drugs 20110101
Anti-inflammatory effects of Chinese medicinal herbs on cerebral ischemia. Chinese medicine 20110101
Extension of lifespan in C. elegans by naphthoquinones that act through stress hormesis mechanisms. PloS one 20110101
Detailed investigations on the solid cell culture and antimicrobial activities of the Iranian Arnebia euchroma. Journal of biomedicine & biotechnology 20110101
Expression of Pigment Cell-Specific Genes in the Ontogenesis of the Sea Urchin Strongylocentrotus intermedius. Evidence-based complementary and alternative medicine : eCAM 20110101
Shikonin increases glucose uptake in skeletal muscle cells and improves plasma glucose levels in diabetic Goto-Kakizaki rats. PloS one 20110101
Anticancer activities of six selected natural compounds of some Cameroonian medicinal plants. PloS one 20110101
Is nitric oxide decrease observed with naphthoquinones in LPS stimulated RAW 264.7 macrophages a beneficial property? PloS one 20110101
Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding. PloS one 20110101
β-Lapachone induces heart morphogenetic and functional defects by promoting the death of erythrocytes and the endocardium in zebrafish embryos. Journal of biomedical science 20110101
The Role of Heme and Reactive Oxygen Species in Proliferation and Survival of Trypanosoma cruzi. Journal of parasitology research 20110101
Acaricidal effect of an isolate from Hoslundia opposita vahl against Amblyomma variegatum (Acari: Ixodidae). Pharmacognosy research 20110101
Antioxidant Activities of Plumbagin and Its Cu (II) Complex. Bioinorganic chemistry and applications 20110101
Amelioration of experimental autoimmune encephalomyelitis by plumbagin through down-regulation of JAK-STAT and NF-κB signaling pathways. PloS one 20110101
Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones. Molecular biology international 20110101
Cytotoxicity of naphthoquinones and their capacity to generate reactive oxygen species is quenched when conjugated with gold nanoparticles. International journal of nanomedicine 20110101
Expression patterns of glutathione transferase gene (GstI) in maize seedlings under juglone-induced oxidative stress. International journal of molecular sciences 20110101
Potential of herbs in skin protection from ultraviolet radiation. Pharmacognosy reviews 20110101
A novel electrochemical method to detect cell surface carbohydrates and target cells. Analytical and bioanalytical chemistry 20101201
Immunomodulatory effects of betulinic acid from the bark of white birch on mice. Journal of veterinary science 20101201
Rate enhancement of an interfacial biochemical reaction through localization of substrate and enzyme by an adaptor domain. The journal of physical chemistry. B 20101125
Role of quinones in the ascorbate reduction rates of S-nitrosoglutathione. Free radical biology & medicine 20101115
A proteomic analysis of the mechanism of action of naphthoimidazoles in Trypanosoma cruzi epimastigotes in vitro. Journal of proteomics 20101110
Synthesis of 1,2-annulated and 1,2-unsubstituted pyrrolo[2,1,5-de]quinolizin-5-ones (cycl[3.3.2]azin-5-ones) via [3+2] cycloadditions of 1-oxoquinolizinium ylides with cyclic alkenes. Organic & biomolecular chemistry 20101107
Chemical constituents from Aphanamixis grandifolia. Chemical & pharmaceutical bulletin 20101101
Study on acute toxicity and structure-activity relationship of zebrafish (Danio rerio) exposed to naphthoquinones. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20101001
6,6'-Dimethoxygossypolone. Acta crystallographica. Section C, Crystal structure communications 20101001
Shikonin protects mouse brain against cerebral ischemia/reperfusion injury through its antioxidant activity. European journal of pharmacology 20100925
Anthraquinone, cyclopentanone, and naphthoquinone derivatives from the sea fan-derived fungi Fusarium spp. PSU-F14 and PSU-F135. Journal of natural products 20100924
Differential cellular responses to protein adducts of naphthoquinone and monocrotaline pyrrole. Chemical research in toxicology 20100920
Total synthesis and anticancer activities of (-)- and (+)-thespesone. The Journal of organic chemistry 20100917
In vitro antiamyloidogenic properties of 1,4-naphthoquinones. Biochemical and biophysical research communications 20100910
Identification of potent virtual leads to design novel indoleamine 2,3-dioxygenase inhibitors: pharmacophore modeling and molecular docking studies. European journal of medicinal chemistry 20100901
Antiviral agents 2. Synthesis of trimeric naphthoquinone analogues of conocurvone and their antiviral evaluation against HIV. Bioorganic & medicinal chemistry 20100901
Scope and mechanism of allylic C-H amination of terminal alkenes by the palladium/PhI(OPiv)2 catalyst system: insights into the effect of naphthoquinone. Journal of the American Chemical Society 20100901
2-Methoxystypandrone represses RANKL-mediated osteoclastogenesis by down-regulating formation of TRAF6-TAK1 signalling complexes. British journal of pharmacology 20100901
Complete genome sequence of Meiothermus ruber type strain (21). Standards in genomic sciences 20100830
Lactones and quinones from the tubers of Sinningia aggregata. Journal of natural products 20100827
Synthesis of naturally occurring naphthoquinone epoxides and application in the synthesis of beta-lapachone. Organic & biomolecular chemistry 20100821
Structure and reactivity of Bacillus subtilis MenD catalyzing the first committed step in menaquinone biosynthesis. Journal of molecular biology 20100813
A versatile synthesis of fumaquinone. The Journal of organic chemistry 20100806
Suppressive effects of 1,4-dihydroxy-2-naphthoic acid administration on bone resorption. Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20100801
Dietary phylloquinone and menaquinones intakes and risk of type 2 diabetes. Diabetes care 20100801
Synthesis and biological evaluation of naphthoquinone analogs as a novel class of proteasome inhibitors. Bioorganic & medicinal chemistry 20100801
Evaluation and structure-activity relationship study of acute toxicity of naphthoquinones to Photobacterium phosphoreum, Photobacterium T3B. Bulletin of environmental contamination and toxicology 20100801
Direct and rapid electrochemical immunosensing system based on a conducting polymer. Talanta 20100715
Lapachol induces clastogenic effects in rats. Planta medica 20100601
Cytotoxicity of new alkylamino- and phenylamino-containing polyfluorinated derivatives of 1,4-naphthoquinone. European journal of medicinal chemistry 20100601
'On water' assisted synthesis and biological evaluation of nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents. European journal of medicinal chemistry 20100601
A naphthoquinone derivative can induce anemia through phosphatidylserine exposure-mediated erythrophagocytosis. The Journal of pharmacology and experimental therapeutics 20100501
The evaluation of quinonoid compounds against Trypanosoma cruzi: synthesis of imidazolic anthraquinones, nor-beta-lapachone derivatives and beta-lapachone-based 1,2,3-triazoles. Bioorganic & medicinal chemistry 20100501
1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes. Archives of biochemistry and biophysics 20100415
Comparison of the cytotoxic effect of lapachol, alpha-lapachone and pentacyclic 1,4-naphthoquinones on human leukemic cells. Investigational new drugs 20100401
Effect of hydroxy substituent on the prooxidant action of naphthoquinone compounds. Toxicology in vitro : an international journal published in association with BIBRA 20100401
Profiling the NIH Small Molecule Repository for compounds that generate H2O2 by redox cycling in reducing environments. Assay and drug development technologies 20100401
Development of sensitivity-improved fluorescence-linked immunosorbent assay using a fluorescent single-domain antibody against the bioactive naphthoquinone, plumbagin. Analytical and bioanalytical chemistry 20100401
Three new compounds from Arnebia euchroma. Journal of Asian natural products research 20100401
HIV-1 Ribonuclease H: Structure, Catalytic Mechanism and Inhibitors. Viruses 20100401
Cytotoxic activity of naphthoquinones with special emphasis on juglone and its 5-O-methyl derivative. Chemico-biological interactions 20100330
Small molecule colorimetric probes for specific detection of human arylamine N-acetyltransferase 1, a potential breast cancer biomarker. Journal of the American Chemical Society 20100317
Prediction of lambda(max) of 1,4-naphthoquinone derivatives using ant colony optimization. Analytica chimica acta 20100317
Quantum mechanical/molecular mechanical modeling finds Diels-Alder reactions are accelerated less on the surface of water than in water. Journal of the American Chemical Society 20100310
Inhibition of beta-lactamase by 1,4-naphthalenedione from the plant Holoptelea integrifolia. Applied biochemistry and biotechnology 20100301
Naphthoquinones, anthraquinones and naphthalene derivatives from the bulbs of Eleutherine americana. Planta medica 20100301
Induced production of antifungal naphthoquinones in the pitchers of the carnivorous plant Nepenthes khasiana. Journal of experimental botany 20100301
Extensive Analysis of Elastase-Induced Pulmonary Emphysema in Rats: ALP in the Lung, a New Biomarker for Disease Progression? Journal of clinical biochemistry and nutrition 20100301
Oxidative stress induction by (+)-cordiaquinone J triggers both mitochondria-dependent apoptosis and necrosis in leukemia cells. Chemico-biological interactions 20100212
Transforming rhinacanthin analogues from potent anticancer agents into potent antimalarial agents. Journal of medicinal chemistry 20100211
Design and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1). Journal of medicinal chemistry 20100211
Evidence for NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated quinone-dependent redox cycling via plasma membrane electron transport: A sensitive cellular assay for NQO1. Free radical biology & medicine 20100201
Naphthoquinones and anthraquinones from scent glands of a dyspnoid Harvestman, Paranemastoma quadripunctatum. Journal of chemical ecology 20100201
Isolation of 1,4-naphthalenedione, an antibacterial principle from the leaves of Holoptelea integrifolia and its activity against beta-lactam resistant Staphylococcus aureus. Indian journal of biochemistry & biophysics 20100201
Cytotoxicity of new n-butylamino and sulfur-containing derivatives of polyfluorinated 1,4-naphthoquinone. European journal of medicinal chemistry 20100101
Reaction of naphthoquinones with substituted nitromethanes. Facile synthesis and antifungal activity of naphtho[2,3-d]isoxazole-4,9-diones. Bioorganic & medicinal chemistry letters 20100101
New naphthoquinone from the root of Lygodium japonicum (Thunb.) Sw. Journal of natural medicines 20100101
A chemical genetic screen for modulators of asymmetrical 2,2'-dimeric naphthoquinones cytotoxicity in yeast. PloS one 20100101
Complete phenotypic recovery of an Alzheimer's disease model by a quinone-tryptophan hybrid aggregation inhibitor. PloS one 20100101
A systematic investigation of Escherichia coli central carbon metabolism in response to superoxide stress. BMC systems biology 20100101
Analysis of polycyclic aromatic hydrocarbons and their oxygen-containing derivatives and metabolites in soils. Journal of environmental quality 20100101
Current and developing therapeutic agents in the treatment of Chagas disease. Drug design, development and therapy 20100101
A role of ygfZ in the Escherichia coli response to plumbagin challenge. Journal of biomedical science 20100101
Expression of 3-hydroxy-3-methylglutaryl-CoA reductase, p-hydroxybenzoate-m-geranyltransferase and genes of phenylpropanoid pathway exhibits positive correlation with shikonins content in arnebia [Arnebia euchroma (Royle) Johnston]. BMC molecular biology 20100101
Synthetic lapachol derivatives relax guinea-pig ileum by blockade of the voltage-gated calcium channels. Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101
Antihyperglycemic activity of Tectona grandis Linn. bark extract on alloxan induced diabetes in rats. International journal of Ayurveda research 20100101
Synthesis, photochemical and photoinduced antibacterial activity studies of meso-Tetra(pyren-1-yl)porphyrin and its Ni, Cu and Zn complexes. Scientia pharmaceutica 20100101
Cytotoxic terpene quinones from marine sponges. Marine drugs 20100101
Comparison of healing time of the 2 degree burn wounds with two dressing methods of fundermol herbal ointment and 1% silver sulfadiazine cream. Iranian journal of nursing and midwifery research 20100101
Genotoxicity of lapachol evaluated by wing spot test of Drosophila melanogaster. Genetics and molecular biology 20100101
Protective effect of stem bark of Ceiba pentandra linn. against paracetamol-induced hepatotoxicity in rats. Pharmacognosy research 20100101
Cyclodextrins in delivery systems: Applications. Journal of pharmacy & bioallied sciences 20100101
Cameroonian medicinal plants: pharmacology and derived natural products. Frontiers in pharmacology 20100101
A bacterial biosensor for oxidative stress using the constitutively expressed redox-sensitive protein roGFP2. Sensors (Basel, Switzerland) 20100101
Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs. Pharmacognosy reviews 20100101
Enaminones in heterocyclic synthesis: a novel route to tetrahydropyrimidines, dihydropyridines, triacylbenzenes and naphthofurans under microwave irradiation. Molecules (Basel, Switzerland) 20091225
N-Heterocyclic carbene-catalyzed monoacylation of 1,4-naphthoquinones with aldehydes. The Journal of organic chemistry 20091218
Chemical constituents from the stems of Diospyros maritima. Molecules (Basel, Switzerland) 20091215
Insulin-like growth factor-1 protects preimplantation embryos from anti-developmental actions of menadione. Archives of toxicology 20091101
Acidiplasma aeolicum gen. nov., sp. nov., a euryarchaeon of the family Ferroplasmaceae isolated from a hydrothermal pool, and transfer of Ferroplasma cupricumulans to Acidiplasma cupricumulans comb. nov. International journal of systematic and evolutionary microbiology 20091101
Application of MEKC and monolithic CEC for the analysis of bioactive naphthoquinones in Eleutherine americana. Electrophoresis 20091101
Biosynthetic origin of 2,3-epoxysesamone in a Sesamum indicum hairy root culture. Bioscience, biotechnology, and biochemistry 20091101
4-(8-Hydr-oxy-3-methyl-1,4-dioxo-1,4-dihydro-2-naphth-yl)butanoic acid. Acta crystallographica. Section E, Structure reports online 20091101
Single-electron transfer in palladium complexes of 1,4-naphthoquinone-containing bis(pyrazol-1-yl)methane ligands. Inorganic chemistry 20091005
Anti-allergic principles of Rhinacanthus nasutus leaves. Phytomedicine : international journal of phytotherapy and phytopharmacology 20091001
Three new naphthoquinone pigments isolated from the freshwater fungus, Astrosphaeriella papuana. Planta medica 20091001
Juglone, a naphthoquinone from walnut, exerts cytotoxic and genotoxic effects against cultured melanoma tumor cells. Cell biology international 20091001
TW96, a synthetic 1,4-naphthoquinone, differentially regulates vascular and endothelial cells survival. Vascular pharmacology 20091001
Investigation of the cumulative tissue doses of naphthoquinones in human serum using protein adducts as biomarker of exposure. Chemico-biological interactions 20090914
Lactococcus lactis catalyses electricity generation at microbial fuel cell anodes via excretion of a soluble quinone. Bioelectrochemistry (Amsterdam, Netherlands) 20090901
Plumbagin induces cell death through a copper-redox cycle mechanism in human cancer cells. Mutagenesis 20090901
An isolable o-quinodimethane and its fixation of molecular oxygen to give an endoperoxide. Chemical communications (Cambridge, England) 20090828
Azolyacetones as precursors to indoles and naphthofurans facilitated by microwave irradiation with simultaneous cooling. Molecules (Basel, Switzerland) 20090811
Design, synthesis and biological evaluation of novel nitrogen and sulfur containing hetero-1,4-naphthoquinones as potent antifungal and antibacterial agents. European journal of medicinal chemistry 20090801
Gas-phase dissociation of 1,4-naphthoquinone derivative anions by electrospray ionization tandem mass spectrometry. Journal of mass spectrometry : JMS 20090801
Xanthoradones, new potentiators of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Penicillium radicum FKI-3765-2 II. Structure elucidation. The Journal of antibiotics 20090801
Cribrarione C, a naphthoquinone pigment from the myxomycete Cribraria meylanii. Chemical & pharmaceutical bulletin 20090801
(+/-)-catechin: chemical weapon, antioxidant, or stress regulator? Journal of chemical ecology 20090801
Naphtho[2,3-d]isoxazole-4,9-dione-3-carboxylates: potent, non-cytotoxic, antiapoptotic agents. Chemico-biological interactions 20090715
The comparative toxicity to soil invertebrates of natural chemicals and their synthetic analogues. Chemosphere 20090701
Induction of apoptosis by rhinacanthone isolated from Rhinacanthus nasutus roots in human cervical carcinoma cells. Biological & pharmaceutical bulletin 20090701
Functional characterization of LePGT1, a membrane-bound prenyltransferase involved in the geranylation of p-hydroxybenzoic acid. The Biochemical journal 20090626
1,4-Naphthoquinone is a potent inhibitor of human cancer cell growth and angiogenesis. Cancer letters 20090608
The correlation of cathodic peak potentials of vitamin K(3) derivatives and their calculated electron affinities. The role of hydrogen bonding and conformational changes. Biochimica et biophysica acta 20090601
Effects of rhinacanthins from Rhinacanthus nasutus on nitric oxide, prostaglandin E2 and tumor necrosis factor-alpha releases using RAW264.7 macrophage cells. Phytomedicine : international journal of phytotherapy and phytopharmacology 20090601
Reductive reaction mechanisms of the azo dye Orange II in aqueous solution and in cellulose: from radical intermediates to products. The journal of physical chemistry. A 20090528
Shikonin exerts antitumor activity via proteasome inhibition and cell death induction in vitro and in vivo. International journal of cancer 20090515
Quinone-enhanced reduction of nitric oxide by xanthine/xanthine oxidase. Chemical research in toxicology 20090501
Lipophilic 1,4-naphthoquinone derivatives: synthesis and redox properties in solution and entrapped in the aqueous cubic liquid-crystalline phase of monoolein. Chemistry and physics of lipids 20090501
[Determination of nitroaromatics and cyclo ketones in sea water' by gas chromatography coupled with activated carbon fiber solid-phase micro-extraction]. Se pu = Chinese journal of chromatography 20090501
Effect of quinone on the fluorescence decay dynamics of endogenous flavin bound to bacterial luciferase. Biophysical chemistry 20090401
The influence of acetylshikonin, a natural naphthoquinone, on the production of leukotriene B4 and thromboxane A2 in rat neutrophils. European journal of pharmacology 20090401
5-Chloro-8-hydr-oxy-6-methyl-1,4-naphthoquinone. Acta crystallographica. Section E, Structure reports online 20090401
Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress. Chemico-biological interactions 20090316
Bioactivities of simplified adociaquinone B and naphthoquinone derivatives against Cdc25B, MKP-1, and MKP-3 phosphatases. Bioorganic & medicinal chemistry 20090315
Reduction of hydrophilic ubiquinones by the flavin in mitochondrial NADH:ubiquinone oxidoreductase (Complex I) and production of reactive oxygen species. Biochemistry 20090310
Oxidative reactions of tetrametal Pd(0)...Mo(II)-Mo(II)...Pd(0) clusters: electrochemical communication of two Pd(0) centers through the Mo(2) moiety and oxidative formation of a Pd(I)-Mo(II)-Mo(II)-Pd(I) array. Inorganic chemistry 20090302
Cytotoxic, genotoxic and oxidative stress induced by 1,4-naphthoquinone in B16F1 melanoma tumor cells. Toxicology in vitro : an international journal published in association with BIBRA 20090301
Characterization of the quinone reductase activity of the ferric reductase B protein from Paracoccus denitrificans. Archives of biochemistry and biophysics 20090301
Construction and expression of specificity-improved single-chain variable fragments against the bioactive naphthoquinone, plumbagin. Biological & pharmaceutical bulletin 20090301
Surface immobilization of PSI using vitamin K1-like molecular wires for fabrication of a bio-photoelectrode. Journal of nanoscience and nanotechnology 20090301
Different cell death pathways induced by drugs in Trypanosoma cruzi: an ultrastructural study. Micron (Oxford, England : 1993) 20090201
Chemiluminescence assay for quinones based on generation of reactive oxygen species through the redox cycle of quinone. Analytical and bioanalytical chemistry 20090201
N-(3-Bromo-1,4-dioxo-1,4-dihydro-2-naphth-yl)-4-fluoro-N-(4-fluoro-benzo-yl)benzamide. Acta crystallographica. Section E, Structure reports online 20090201
Divergent synthesis of three classes of aryl N-glycosides by solvent control. The Journal of organic chemistry 20090116
Synthesis and evaluation of Hsp90 inhibitors that contain the 1,4-naphthoquinone scaffold. Bioorganic & medicinal chemistry 20090115
Quinone-enhanced sonochemical production of nitric oxide from s-nitrosoglutathione. Ultrasonics sonochemistry 20090101
New naphthoquinone derivatives from the ascomycete IBWF79B-90A. Zeitschrift fur Naturforschung. C, Journal of biosciences 20090101
Biological evaluation of 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone as an anti-breast cancer agent. Anticancer research 20090101
Irritant contact dermatitis from plants. Dermatitis : contact, atopic, occupational, drug 20090101
Effects of different quinoid redox mediators on the simultaneous removal of p-cresol and sulphide in a denitrifying process. Water science and technology : a journal of the International Association on Water Pollution Research 20090101
Extracellular and intracellular polyphenol oxidases cause opposite effects on sensitivity of Streptomyces to phenolics: a case of double-edged sword. PloS one 20090101
Structural basis for substrate specificity in human monomeric carbonyl reductases. PloS one 20090101
N-(3-Bromo-1,4-dioxo-1,4-dihydro-2-naphth-yl)-2-chloro-N-(2-chloro-benzoyl)benzamide. Acta crystallographica. Section E, Structure reports online 20090101
2-Amino-4-(2-chloro-phen-yl)-5,10-dioxo-5,10-dihydro-4H-benzo[g]chromene-3-carbonitrile. Acta crystallographica. Section E, Structure reports online 20090101
2-Chloro-3-(4-chloro-benzamido)-1,4-naphthoquinone. Acta crystallographica. Section E, Structure reports online 20090101
Modulatory effects of Tabebuia impetiginosa (Lamiales, Bignoniaceae) on doxorubicin-induced somatic mutation and recombination in Drosophila melanogaster. Genetics and molecular biology 20090101
Photoionization studies on various quinones by an infrared laser desorption/tunable VUV photoionization TOF mass spectrometry. Journal of mass spectrometry : JMS 20081201
Characterization, reactivity and photosensitizing properties of the triplet excited state of alpha-lapachone. Physical chemistry chemical physics : PCCP 20081128
Shikonin derivatives inhibited LPS-induced NOS in RAW 264.7 cells via downregulation of MAPK/NF-kappaB signaling. Journal of ethnopharmacology 20081120
Effect of vitamin K supplementation on insulin resistance in older men and women. Diabetes care 20081101
Chemical substructures that enrich for biological activity. Bioinformatics (Oxford, England) 20081101
Shikonin, acetylshikonin, and isobutyroylshikonin inhibit VEGF-induced angiogenesis and suppress tumor growth in lewis lung carcinoma-bearing mice. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081101
In vitro evaluation of the growth inhibitory activities of 15 drugs against Babesia gibsoni (Aomori strain). Veterinary parasitology 20081020
Semisynthesis and antitumoral activity of 2-acetylfuranonaphthoquinone and other naphthoquinone derivatives from lapachol. Bioorganic & medicinal chemistry letters 20081015
Vinyl ketone reduction by three distinct Gluconobacter oxydans 621H enzymes. Applied microbiology and biotechnology 20081001
Shikonins attenuate microglial inflammatory responses by inhibition of ERK, Akt, and NF-kappaB: neuroprotective implications. Neuropharmacology 20081001
A new method for quantifiable and controlled dosage of particulate matter for in vitro studies: the electrostatic particulate dosage and exposure system (EPDExS). Toxicology in vitro : an international journal published in association with BIBRA 20081001
Desorption and ionization mechanisms in desorption atmospheric pressure photoionization. Analytical chemistry 20081001
Novel naphthoquinone and quinolinedione inhibitors of CDC25 phosphatase activity with antiproliferative properties. Bioorganic & medicinal chemistry 20081001
3-Allyl-2-hydr-oxy-5,6,8-trimethoxy-naphthalene-1,4-dione. Acta crystallographica. Section E, Structure reports online 20081001
DMNQ-S17 inhibits constitutive NF-kappaB activation leading to induction of apoptosis through the activation of caspase-3 in human myeloid leukemia U937 cells. Life sciences 20080926
Electrogenerated chemiluminescence of 9,10-diphenylanthracene, rubrene, and anthracene in fluorinated aromatic solvents. The journal of physical chemistry. A 20080918
In vitro toxicity of naphthalene, 1-naphthol, 2-naphthol and 1,4-naphthoquinone on human CFU-GM from female and male cord blood donors. Toxicology in vitro : an international journal published in association with BIBRA 20080901
Synthesis and biological evaluation of naphthalene-1,4-dione derivatives as potent antimycobacterial agents. Medicinal chemistry (Shariqah (United Arab Emirates)) 20080901
Photoreactions of 1,4-naphthoquinone with lysozyme studied by laser flash photolysis and steady-state analysis. Journal of photochemistry and photobiology. B, Biology 20080821
The aza-analogues of 1,4-naphthoquinones are potent substrates and inhibitors of plasmodial thioredoxin and glutathione reductases and of human erythrocyte glutathione reductase. Organic & biomolecular chemistry 20080807
Analysis of naphthoquinone derivatives in the Asian medicinal plant Eleutherine americana by RP-HPLC and LC-MS. Journal of pharmaceutical and biomedical analysis 20080805
Synthesis and biological evaluation of novel naphthoquinone fused cyclic aminoalkylphosphonates and aminoalkylphosphonic monoester. Amino acids 20080801
Nanosecond molecular dynamics simulations of Cdc25B and its complex with a 1,4-naphthoquinone inhibitor: implications for rational inhibitor design. Journal of molecular graphics & modelling 20080801
An adjustment factor for mode-of-action uncertainty with dual-mode carcinogens: the case of naphthalene-induced nasal tumors in rats. Risk analysis : an official publication of the Society for Risk Analysis 20080801
Ascorbic acid potentiates the cytotoxicity of the naphthoquinone 5-methoxy-3,4-dehydroxanthomegnin. Phytochemistry 20080801
The natural naphthoquinone plumbagin exhibits antiproliferative activity and disrupts the microtubule network through tubulin binding. Biochemistry 20080729
Purified compounds and extracts from Euclea species with antimycobacterial activity against Mycobacterium bovis and fast-growing mycobacteria. Biological & pharmaceutical bulletin 20080701
Isoeleutherin and eleutherinol, naturally occurring selective modulators of Th cell-mediated immune responses. Biochemical and biophysical research communications 20080627
Rapid assessment of the latent hazard posed by dissolved mercaptans within aqueous effluent. Journal of hazardous materials 20080615
Comparison of the cytotoxic activities of naturally occurring hydroxyanthraquinones and hydroxynaphthoquinones. European journal of medicinal chemistry 20080601
Molluscicidal activity of 2-hydroxy-[1,4]naphthoquinone and derivatives. Anais da Academia Brasileira de Ciencias 20080601
Entropic changes control the charge separation process in triads mimicking photosynthetic charge separation. The journal of physical chemistry. A 20080508
Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer. Parasitology research 20080501
Synthesis and anti-Trypanosoma cruzi activity of derivatives from nor-lapachones and lapachones. Bioorganic & medicinal chemistry 20080501
Alkannin/shikonin mixture from roots of Onosma echioides (L.) L.: extraction method study and quantification. Journal of separation science 20080401
Hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone in Swiss Webster mice. Chemico-biological interactions 20080327
Indoleamine 2,3-dioxygenase is the anticancer target for a novel series of potent naphthoquinone-based inhibitors. Journal of medicinal chemistry 20080327
Growth inhibition and induction of apoptosis in human oral squamous cell carcinoma Tca-8113 cell lines by Shikonin was partly through the inactivation of NF-kappaB pathway. Phytotherapy research : PTR 20080301
Isolation and purification of acetylshikonin and beta-acetoxyisovalerylshikonin from cell suspension cultures of Arnebia euchroma (Royle) Johnston using rapid preparative HPLC. Journal of separation science 20080301
2,3-Bis(2-chloro-benz-yl)naphthalene-1,4-dione. Acta crystallographica. Section E, Structure reports online 20080301
Genotoxicity of aminohydroxynaphthoquinones in bacteria, yeast, and Chinese hamster lung fibroblast cells. Mutation research 20080227
Antimycobacterial substances from Phaeosphaeria sp BCC8292. Planta medica 20080201
Surface photochemistry of the herbicide napropamide. The role of the media and environmental factors in directing the fates of intermediates. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080101
Enantioselective epoxidation of electrophilic olefins by using glycosyl hydroperoxides. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
NLNQ-1, a 2-[3-(2-nitro-1-imidazolyl) propylamino]-3-chloro-1,4-naphthoquinone, as a hypoxia-selective cytotoxin and radiosensitizer. In vivo (Athens, Greece) 20080101
pH effect on the one-electron photooxidation of 5-methylcytosine with naphthoquinone sensitizer. Nucleic acids symposium series (2004) 20080101
Caspase-3-mediated cleavage of p65/RelA results in a carboxy-terminal fragment that inhibits IkappaBalpha and enhances HIV-1 replication in human T lymphocytes. Retrovirology 20080101
Cytotoxicity mechanism of two naphthoquinones (menadione and plumbagin) in Saccharomyces cerevisiae. PloS one 20080101
Immunological studies on the aerial roots of the Indian banyan. Indian journal of pharmaceutical sciences 20080101
A review on plant-derived natural products and their analogs with anti-tumor activity. Indian journal of pharmacology 20080101
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. Proceedings of the National Academy of Sciences of the United States of America 20071218
Activity of 7-methyljuglone derivatives against Mycobacterium tuberculosis and as subversive substrates for mycothiol disulfide reductase. Bioorganic & medicinal chemistry 20071215
Binding mode analysis of topoisomerase inhibitors, 6-arylamino-7-chloro-quinazoline-5,8-diones, within the cleavable complex of human topoisomerase I and DNA. Archives of pharmacal research 20071201
Naphthalene metabolism and growth inhibition by naphthalene in Polaromonas naphthalenivorans strain CJ2. Microbiology (Reading, England) 20071101
Heptaketides from Corynespora sp. inhabiting the cavern beard lichen, Usnea cavernosa: first report of metabolites of an endolichenic fungus. Journal of natural products 20071101
The influence of water quality on the toxicity and degradation of juglone (5-hydroxy 1,4-naphthoquinone). Environmental technology 20071001
Electron transfer from aromatic amino acids to triplet quinones. Journal of photochemistry and photobiology. B, Biology 20070925
Induction of apoptosis by plumbagin through reactive oxygen species-mediated inhibition of topoisomerase II. Toxicology and applied pharmacology 20070915
Anti-estrogenic activity of mansorins and mansonones from the heartwood of Mansonia gagei DRUMM. Chemical & pharmaceutical bulletin 20070901
[Study on myxomycetes as a new source of bioactive natural products]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070901
Effects of naphthoquinone on airway responsiveness in the presence or absence of antigen in mice. Archives of toxicology 20070801
The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors. Bioorganic & medicinal chemistry 20070801
Synthesis and reaction mechanism of a photoremovable protecting group based on 1,4-naphthoquinone. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20070801
Reproductive toxicity of lapachol in adult male Wistar rats submitted to short-term treatment. Phytotherapy research : PTR 20070701
Double mode of inhibition-inducing interactions of 1,4-naphthoquinone with urease: arylation versus oxidation of enzyme thiols. Bioorganic & medicinal chemistry 20070615
Cytotoxicity of lawsone and cytoprotective activity of antioxidants in catalase mutant Escherichia coli. Toxicology 20070603
Quinone-induced inhibition of urease: elucidation of its mechanisms by probing thiol groups of the enzyme. Bioorganic chemistry 20070601
Effect of nonionic surfactants on the oxidation of carbaryl by anodic Fenton treatment. Water research 20070601
Unusual naphthoquinone derivatives from the twigs of Avicennia marina. Journal of natural products 20070601
Thioredoxin glutathione reductase from Schistosoma mansoni: an essential parasite enzyme and a key drug target. PLoS medicine 20070601
[Naphthoquinones and their pharmacological properties]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20070601
Protection of human keratinocytes from UVB-induced inflammation using root extract of Lithospermum erythrorhizon. Biological & pharmaceutical bulletin 20070501
Shikonin circumvents cancer drug resistance by induction of a necroptotic death. Molecular cancer therapeutics 20070501
Oxygen uptake upon photolysis of 1,4-benzoquinones and 1,4-naphthoquinones in air-saturated aqueous solution in the presence of formate, amines, ascorbic acid, and alcohols. The journal of physical chemistry. A 20070419
Terpenoid-related metabolites from a formosan soft coral Nephthea chabrolii. Chemical & pharmaceutical bulletin 20070401
Diels-Alder reactions of 4-alkenylthiazoles: a new approach to thiazole functionalization. The Journal of organic chemistry 20070316
A new EGFR inhibitor induces apoptosis in colon cancer cells. Biochemical and biophysical research communications 20070309
Naphthoquinones as broad spectrum biocides for treatment of ship's ballast water: toxicity to phytoplankton and bacteria. Water research 20070301
Synthesis and pharmacophore modeling of naphthoquinone derivatives with cytotoxic activity in human promyelocytic leukemia HL-60 cell line. Journal of medicinal chemistry 20070222
Disparity in the induction of glutathione depletion, ROS formation, poly(ADP-ribose) polymerase-1 activation, and apoptosis by quinonoid derivatives of naphthalene in human cultured cells. Chemico-biological interactions 20070220
Naphthoquinone enhances antigen-related airway inflammation in mice. The European respiratory journal 20070201
Antifungal chemical compounds identified using a C. elegans pathogenicity assay. PLoS pathogens 20070201
Effects of different carbon and nitrogen sources on naphthoquinone production of Cordyceps unilateralis BCC 1869. Applied biochemistry and biotechnology 20070201
Antiproliferative activity of NQ304, a synthetic 1,4-naphthoquinone, is mediated via the suppressions of the PI3K/Akt and ERK1/2 signaling pathways in PDGF-BB-stimulated vascular smooth muscle cells. Vascular pharmacology 20070101
Potent inhibition of serum-stimulated responses in vascular smooth muscle cell proliferation by 2-chloro-3-(4-hexylphenyl)-amino-1,4-naphthoquinone, a newly synthesized 1,4-naphthoquinone derivative. Biological & pharmaceutical bulletin 20070101
Structure-activity relationships in the haemolytic activity and nephrotoxicity of derivatives of 1,2- and 1,4-naphthoquinone. Journal of applied toxicology : JAT 20070101
Variations in product in reactions of naphthoquinone with primary amines. Beilstein journal of organic chemistry 20070101
2-Arylhydrazononitriles as building blocks in heterocyclic synthesis: A novel route to 2-substituted-1,2,3-triazoles and 1,2,3-triazolo[4,5-b]pyridines. Beilstein journal of organic chemistry 20070101
Relationship between redox activity and chemical speciation of size-fractionated particulate matter. Particle and fibre toxicology 20070101
Cytotoxicity of 2,3-dichloro-5,8-dimethoxy-1,4-naphthoquinone in androgen-dependent and -independent prostate cancer cell lines. Anticancer research 20070101
Site-selective strand cleavage at methylated cytosine: regional effect of naphthoquinone chromophore on the one-electron photooxidation of 5-methylcytosine and positive charge transfer in DNA. Nucleic acids symposium series (2004) 20070101
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress. Journal of biology 20070101
The effect of chlorpyrifos-oxon and other xenobiotics on the human cytochrome P450-dependent metabolism of naphthalene and deet. Drug metabolism and drug interactions 20070101
Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design. Drug target insights 20070101
Selective determination of quinones by high-performance liquid chromatography with on-line post column ultraviolet irradiation and peroxyoxalate chemiluminescence detection. Journal of chromatography. A 20061110
Control of pyramidal inversion rates by redox switching. Journal of the American Chemical Society 20061108
Griseusin C, a novel quinone derivative from a marine-derived fungus Penicillium sp. Archives of pharmacal research 20061101
Aminonaphthoquinone induces oxidative stress in Staphylococcus aureus. Biochemistry and cell biology = Biochimie et biologie cellulaire 20061001
Synthesis of new 2-vinylation products of indole via a Michael-type addition reaction with dimethyl acetylenedicarboxylate and their Diels-Alder reactivity as precursors of new carbazoles. The Journal of organic chemistry 20060929
Using of liquid chromatography coupled with diode array detector for determination of naphthoquinones in plants and for investigation of influence of pH of cultivation medium on content of plumbagin in Dionaea muscipula. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914
SH-7, a new synthesized shikonin derivative, exerting its potent antitumor activities as a topoisomerase inhibitor. International journal of cancer 20060901
A naphthoquinone derivative, shikonin, has insulin-like actions by inhibiting both phosphatase and tensin homolog deleted on chromosome 10 and tyrosine phosphatases. Molecular pharmacology 20060901
Anti-cancer activities of 1,4-naphthoquinones: a QSAR study. Anti-cancer agents in medicinal chemistry 20060901
Simultaneous determination of naphthoquinone derivatives in Boraginaceous herbs by high-performance liquid chromatography. Analytica chimica acta 20060901
A fluoro analogue of the menadione derivative 6-[2'-(3'-methyl)-1',4'-naphthoquinolyl]hexanoic acid is a suicide substrate of glutathione reductase. Crystal structure of the alkylated human enzyme. Journal of the American Chemical Society 20060823
A new method for the synthesis of 2-hydroxy-3-nitro-1,4-naphthoquinones: application to regiospecific preparation of unsymmetrical nitrobiquinones. The Journal of organic chemistry 20060818
Regiocontrolled synthesis and HIV inhibitory activity of unsymmetrical binaphthoquinone and trimeric naphthoquinone derivatives of conocurvone. Bioorganic & medicinal chemistry 20060815
Sennidin stimulates glucose incorporation in rat adipocytes. Life sciences 20060808
Plumbago zeylanica action on blood coagulation profile with and without blood volume reduction. Vascular pharmacology 20060801
Electrocoagulation of quinone pigments. Molecules (Basel, Switzerland) 20060714
Generation of benzocyclobutadiene derivatives from zirconaindene derivatives. The Journal of organic chemistry 20060707
UV/Vis spectra and solubility of some naphthoquinones, and the extraction behavior of plumbagin from Plumbago scandens roots in supercritical CO2. Analytical and bioanalytical chemistry 20060701
Development of a process for the production of the anticancer lead compound pleurotin by fermentation of Hohenbuehelia atrocaerulea. Journal of industrial microbiology & biotechnology 20060601
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Analysis of rice glycosyl hydrolase family 1 and expression of Os4bglu12 beta-glucosidase. BMC plant biology 20060101
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An antithrombotic agent, NQ301, inhibits thromboxane A2 receptor and synthase activity in rabbit platelets. Basic & clinical pharmacology & toxicology 20050901
Design, synthesis, and biological evaluation of novel naphthoquinone derivatives with CDC25 phosphatase inhibitory activity. Bioorganic & medicinal chemistry 20050815
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Biotechnological production and bioactivities of mollisin and two new, structurally related fungal naphthoquinone metabolites. Chemistry & biodiversity 20050801
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Presence of peroxyradicals in cigarette smoke and the scavenging effect of shikonin, a naphthoquinone pigment. Chemical & pharmaceutical bulletin 20050701
Engineering the substrate specificity of cytochrome P450 CYP102A2 by directed evolution: production of an efficient enzyme for bioconversion of fine chemicals. Biomolecular engineering 20050601
The maillard reaction for sunlight protection. Annals of the New York Academy of Sciences 20050601
Chemical profiles of scent gland secretions in the cyphophthalmid opilionid harvestmen, Siro duricorius and S. exilis. Journal of chemical ecology 20050601
2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds. The Journal of biological chemistry 20050527
Evolution of the pseudo-1,3-dipolar cycloaddition chemistry of SNSMF6 (M = As, Sb) leading to 2,5-dihydroxybenzo-1,3,2-dithiazolylium and 2,7-dicarbonylnaphtha-1,3,2-dithiazolylium salts and their corresponding radicals. Chemical communications (Cambridge, England) 20050514
Biomimetic synthesis of antimalarial naphthoquinones. Journal of the American Chemical Society 20050504
PROPHIS: parabolic trough-facility for organic photochemical syntheses in sunlight. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20050501
Sorption of naphthalene derivatives to soils from a long-term field experiment. Chemosphere 20050401
Novel hydroxyl naphthoquinones with potent Cdc25 antagonizing and growth inhibitory properties. Molecular cancer therapeutics 20050401
Fumaquinone, a new prenylated naphthoquinone from Streptomyces fumanus. The Journal of antibiotics 20050401
Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells. Biological chemistry 20050301
Selective growth-inhibiting effects of compounds identified in Tabebuia impetiginosa inner bark on human intestinal bacteria. Journal of agricultural and food chemistry 20050223
Mechanism of cytotoxicity of catechols and a naphthalenediol in PC12-AC cells: the connection between extracellular autoxidation and molecular electronic structure. Free radical biology & medicine 20050201
Ab initio and semiempirical study of structure and electronic spectra of hydroxy substituted naphthoquinones. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050201
Inactivation and deficiency of core proteins of photosystems I and II caused by genetical phylloquinone and plastoquinone deficiency but retained lamellar structure in a T-DNA mutant of Arabidopsis. The Plant journal : for cell and molecular biology 20050201
Synthesis and cytotoxicity of new aminoterpenylquinones. Bioorganic & medicinal chemistry 20050201
Radical scavenging activity of Alkanna tinctoria root extracts and their main constituents, hydroxynaphthoquinones. Phytotherapy research : PTR 20050201
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Synthesis of the naphthalene-derived inhibitors against Cdc25A dual-specificity protein phosphatase and their biological activity. Bioorganic & medicinal chemistry letters 20050103
Antiplatelet activity of J78 (2-Chloro-3-[2'-bromo, 4'-fluoro-phenyl]-amino-8-hydroxy-1,4-naphthoquinone), an antithrombotic agent, is mediated by thromboxane (TX) A2 receptor blockade with TXA2 synthase inhibition and suppression of cytosolic Ca2+ mobilization. The Journal of pharmacology and experimental therapeutics 20050101
Photoreactions of 1,4-Naphthoquinones: effects of substituents and water on the intermediates and reactivity. Photochemistry and photobiology 20050101
Inhibition of Nox-4 activity by plumbagin, a plant-derived bioactive naphthoquinone. The Journal of pharmacy and pharmacology 20050101
Reversal of a full-length mutant huntingtin neuronal cell phenotype by chemical inhibitors of polyglutamine-mediated aggregation. BMC neuroscience 20050101
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[Biosynthesis of naphthoquinone pigments by fungi of the genus Fusarium]. Prikladnaia biokhimiia i mikrobiologiia 20050101
Anthraquinones sensitize tumor cells to arsenic cytotoxicity in vitro and in vivo via reactive oxygen species-mediated dual regulation of apoptosis. Free radical biology & medicine 20041215
Pharmacological and biological evaluation of a series of substituted 1,4-naphthoquinone bioreductive drugs. Biochemical pharmacology 20041201
A new cytotoxic naphthoquinone from Paepalanthus latipes. Chemical & pharmaceutical bulletin 20041201
Novel meroditerpenoid-related metabolites from the formosan soft coral Nephthea chabrolii. Journal of natural products 20041201
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[Preliminary study on naphthalene-metabolites-albumin adduct as an exposure biomarker for coke oven workers]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20041101
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Quinone-enhanced ascorbate reduction of nitric oxide: role of quinone redox potential. Free radical research 20041001
Synthesis and biological evaluation of novel naphthoquinone derivatives as potential anticancer and antimicrobial agents. Bollettino chimico farmaceutico 20041001
Quinones as antimycobacterial agents. Bioorganic & medicinal chemistry 20040915
Parameters and mechanistic studies on the oxidative ring cleavage of synthetic heterocyclic naphthoquinones by Streptomyces strains. Applied microbiology and biotechnology 20040901
A naphthoquinone derivative from Tectona grandis (Linn.). Journal of Asian natural products research 20040901
Plumbagin quantification in roots of Plumbago scandens L. obtained by different extraction techniques. Anais da Academia Brasileira de Ciencias 20040901
Degradation of juglone by Pleurotus sajor-caju. Mycological research 20040801
Studies on the synthesis of landomycin A. Synthesis of the originally assigned structure of the aglycone, landomycinone, and revision of structure. The Journal of organic chemistry 20040723
Development of a disposable potentiometric sensor for the near patient testing of plasma thiol concentrations. Analytical chemistry 20040701
Search for constituents with neurotrophic factor-potentiating activity from the medicinal plants of paraguay and Thailand. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20040701
Cytotoxic and antimicrobial constituents of the bark of Diospyros maritima collected in two geographical locations in Indonesia. Journal of natural products 20040701
Effects of plant-derived compounds on larvae of a blow fly species that causes secondary myiases: laboratory studies. Phytotherapy research : PTR 20040701
Potentiometric differentiation of mono- and macromolecular thiol within human plasma at carbon fiber electrodes. Journal of the American Chemical Society 20040630
AND/OR bimolecular recognition. Journal of the American Chemical Society 20040609
Synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antiviral, antifungal and anticancer agents. Bioorganic & medicinal chemistry letters 20040607
Catalytic reaction of cytokinin dehydrogenase: preference for quinones as electron acceptors. The Biochemical journal 20040515
Aqueous solutions that model the cytosol: studies on polarity, chemical reactivity and enzyme kinetics. Organic & biomolecular chemistry 20040507
NapGH components of the periplasmic nitrate reductase of Escherichia coli K-12: location, topology and physiological roles in quinol oxidation and redox balancing. The Biochemical journal 20040401
Inhibitory effects of J78, a newly synthesized 1,4-naphthoquinone derivative, on experimental thrombosis and platelet aggregation. Pharmacology 20040401
Design, synthesis and evaluation of novel 1,4-naphthoquinone derivatives as antifungal and anticancer agents. Bioorganic & medicinal chemistry letters 20040308
Alternative quinone substrates and inhibitors of human electron-transfer flavoprotein-ubiquinone oxidoreductase. The Biochemical journal 20040301
Shikonins, phytocompounds from Lithospermum erythrorhizon, inhibit the transcriptional activation of human tumor necrosis factor alpha promoter in vivo. The Journal of biological chemistry 20040213
Antiplatelet and antithrombotic activities of CP201, a newly synthesized 1,4-naphthoquinone derivative. Vascular pharmacology 20040201
Enthalpy of solution of 1,4-naphthoquinone in CO2 + n-pentane in the critical region of the binary mixture: mechanism of solubility enhancement. Chemistry (Weinheim an der Bergstrasse, Germany) 20040123
Photoprocesses of p-naphthoquinones and vitamin K(1): effects of alcohols and amines on the reactivity in solution. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20040101
Albumin adducts of naphthalene metabolites as biomarkers of exposure to polycyclic aromatic hydrocarbons. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040101
Impairment of vascular function of rat thoracic aorta in an endothelium-dependent manner by shikonin/alkannin and derivatives isolated from roots of Macrotomia euchroma. Planta medica 20040101
Structural analysis of naphthoquinone protein adducts with liquid chromatography/tandem mass spectrometry and the scoring algorithm for spectral analysis (SALSA). Rapid communications in mass spectrometry : RCM 20040101
In vitro antispasmodic and anti-inflammatory effects of Drosera rotundifolia. Arzneimittel-Forschung 20040101
[Effect of new hemocorrectors on heart mitochondrial oxidation in hemorrhagic shock]. Biomeditsinskaia khimiia 20040101
Synthesis of regioisomeric analogues of crisamicin A. Organic & biomolecular chemistry 20031207
Involvement of Akt in mitochondria-dependent apoptosis induced by a cdc25 phosphatase inhibitor naphthoquinone analog. FEBS letters 20031204
Cribrarione B, a new naphthoquinone pigment from the myxomycete Cribraria cancellata. Journal of natural products 20031201
Identification of alkylation-sensitive target chaperone proteins and their reactivity with natural products containing Michael acceptor. Archives of pharmacal research 20031201
Isodiospyrin as a novel human DNA topoisomerase I inhibitor. Biochemical pharmacology 20031115
A new approach to evaluating the extent of Michael adduct formation to PAH quinones: tetramethylammonium hydroxide (TMAH) thermochemolysis with GC/MS. Chemical research in toxicology 20031101
Total syntheses of furaquinocin A, B, and E. Journal of the American Chemical Society 20031029
Phototransformation of 1,4-naphthoquinone in aqueous solution. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20031001
Antimicrobial activity in vitro of plumbagin isolated from Plumbago species. Memorias do Instituto Oswaldo Cruz 20031001
The naphthoquinol oxidizing cytochrome bc1 complex of the hyperthermophilic knallgasbacterium Aquifex aeolicus: properties and phylogenetic relationships. Biochemistry 20030916
Total synthesis of 12-methoxydihydrochelerythrine and anti-tumour activity of its quaternary base: toward an efficient synthetic route for 12-alkoxybenzo[c]phenanthridine bases via naphthoquinone monooxime from 2-benzofuranyl-1-tetralone derivative. Organic & biomolecular chemistry 20030907
A new naphthoquinone from Ceiba pentandra. Journal of Asian natural products research 20030901
Cytotoxicity and DNA topoisomerase inhibitory activity of benz[f]indole-4,9-dione analogs. Bioscience, biotechnology, and biochemistry 20030901
1-Methyl anthraquinones and their biogenetic precursors from Stereospermum personatum. Phytochemistry 20030801
Perspective in antimalarial chemotherapy. Current medicinal chemistry 20030701
Dihydrolindbladiones, three new naphthoquinone pigments from a myxomycete Lindbladia tubulina. Journal of natural products 20030701
Suzuki-Miyaura homocoupling of naphthyl triflates using bis(pinacolato)diboron: approaches to the biaryl skeleton of crisamicin A. Organic & biomolecular chemistry 20030621
Activity of quinones on colletotrichum species. Journal of agricultural and food chemistry 20030618
Metal ion-promoted intramolecular electron transfer in a ferrocene-naphthoquinone linked dyad. Continuous change in driving force and reorganization energy with metal ion concentration. Journal of the American Chemical Society 20030611
DNA topoisomerases I and II inhibitory activity of constituents isolated from Juglans mandshurica. Archives of pharmacal research 20030601
Synthesis and biological evaluation of some new substituted naphthoquinones. Bollettino chimico farmaceutico 20030601
Effects of a naphthoquinone analog on tumor growth and apoptosis induction. Archives of pharmacal research 20030501
Protein targets of 1,4-benzoquinone and 1,4-naphthoquinone in human bronchial epithelial cells. Proteomics 20030401
Synthesis of N-quinonyltaurines. Amino acids 20030401
Discriminating redox cycling and arylation pathways of reactive chemical toxicity in trout hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology 20030301
In vitro cytotoxicity activity of Diosquinone, a naphthoquinone epoxide. Phytotherapy research : PTR 20030301
Kinetic and docking studies of the interaction of quinones with the quinone reductase active site. Biochemistry 20030225
New strategies and building blocks for functionalised 9,10-bis(1,3-dithiol-2-ylidene)-9,10-dihydroanthracene derivatives, including pyrrolo-annelated derivatives and pi-extended systems with intramolecular charge-transfer. Organic & biomolecular chemistry 20030207
Mechanisms for naphthalene removal during electrolytic aeration. Water research 20030201
Reactive quinones differentially regulate SAPK/JNK and p38/mHOG stress kinases. Antioxidants & redox signaling 20030201
Effects of hydroxypropyl-beta-cyclodextrin on the chemical stability of a naphthoquinone in aqueous solutions. Die Pharmazie 20030101
The prolyl isomerase Pin1 in breast development and cancer. Breast cancer research : BCR 20030101
Feasibility of atmospheric pressure desorption/ionization on silicon mass spectrometry in analysis of drugs. Rapid communications in mass spectrometry : RCM 20030101
Evidence for redox cycling of lawsone (2-hydroxy-1,4-naphthoquinone) in the presence of the hypoxanthine/xanthine oxidase system. Journal of applied toxicology : JAT 20030101
Naphthoquinone derivatives and lignans from the Paraguayan crude drug 'tayï pytá' (Tabebuia heptaphylla, Bignoniaceae). Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101
[Succivil efficacy in endogenous intoxication]. Eksperimental'naia i klinicheskaia farmakologiia 20030101
Placement and characterization of pairs of luminescent molecules in spatially separated regions of nanostructured thin films. Journal of the American Chemical Society 20021204
K vitamins, PTP antagonism, and cell growth arrest. Journal of cellular physiology 20021201
Stimulatory effect of menaquinone-7 on bone formation in elderly female rat femoral tissues in vitro: prevention of bone deterioration with aging. International journal of molecular medicine 20021201
2-(Pyrrolidin-1-yl)-1,4-naphthoquinone and 2-phenylsulfanyl-3-(pyrrolidin-1-yl)-1,4-naphthoquinone. Acta crystallographica. Section C, Crystal structure communications 20021201
Chloroquinocin, a novel chlorinated naphthoquinone antibiotic from Streptomyces sp., LL-A9227. The Journal of antibiotics 20021201
Why do co-solvents enhance the solubility of solutes in supercritical fluids? New evidence and opinion. Chemistry (Weinheim an der Bergstrasse, Germany) 20021115
Measurement of hemoglobin and albumin adducts of naphthalene-1,2-oxide, 1,2-naphthoquinone and 1,4-naphthoquinone after administration of naphthalene to F344 rats. Chemico-biological interactions 20021020
DYKAT of Baylis-Hillman adducts: concise total synthesis of furaquinocin E. Journal of the American Chemical Society 20021002
Fetal growth in rats treated with lapachol. Contraception 20021001
Magneto-switchable electrocatalytic and bioelectrocatalytic transformations. Chemistry (Weinheim an der Bergstrasse, Germany) 20020916
Synthesis of monocarbenepalladium(0) complexes and their catalytic behavior in cross-coupling reactions of aryldiazonium salts. Chemistry (Weinheim an der Bergstrasse, Germany) 20020902
Cancer therapy with beta-lapachone. Current cancer drug targets 20020901
Stability of hemoglobin and albumin adducts of naphthalene oxide, 1,2-naphthoquinone, and 1,4-naphthoquinone. Toxicological sciences : an official journal of the Society of Toxicology 20020801
Lindbladione and related naphthoquinone pigments from a myxomycete Lindbladia tubulina. Chemical & pharmaceutical bulletin 20020801
High level expression of chorismate pyruvate-lyase (UbiC) and HMG-CoA reductase in hairy root cultures of Lithospermum erythrorhizon. Plant & cell physiology 20020801
Induction of p73beta by a naphthoquinone analog is mediated by E2F-1 and triggers apoptosis in HeLa cells. FEBS letters 20020703
In vitro antimicrobial activity of a new series of 1,4-naphthoquinones. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020701
Direct reaction between shikonin and thiols induces apoptosis in HL60 cells. Biological & pharmaceutical bulletin 20020701
Acute lethal toxicity of environmental pollutants to aquatic organisms. Ecotoxicology and environmental safety 20020601
Naphthoquinone cataract in mice: mitochondrial change and protection by superoxide dismutase. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20020601
Cyclooxygenase-2 inhibitory 1,4-naphthoquinones from Impatiens balsamina L. Biological & pharmaceutical bulletin 20020501
In vitro antifungal activity of naphthoquinone derivatives. Biological & pharmaceutical bulletin 20020501
Three new naphthoquinone derivatives from Diospyros maritima Blume. Chemical & pharmaceutical bulletin 20020501
Synthesis of 2-alkoxy 1,4-naphthoquinone derivatives as antiplatelet, antiinflammatory, and antiallergic agents. Chemical & pharmaceutical bulletin 20020501
Protective effect of aloe extract against the cytotoxicity of 1,4-naphthoquinone in isolated rat hepatocytes involves modulations in cellular thiol levels. Pharmacology & toxicology 20020501
The anatomy and chemistry of the colour bands of grasstree stems (Xanthorrhoea preissii) used for plant age and fire history determination. Annals of botany 20020501
Cellular pharmacology studies of shikonin derivatives. Phytotherapy research : PTR 20020501
Identification of a potent and selective pharmacophore for Cdc25 dual specificity phosphatase inhibitors. Molecular pharmacology 20020401
A new naphthoquinone from Polygonum aviculare. Natural product letters 20020401
[Studies on the inhibition of polyhydroxylated aromatic compounds against HIV-1 integrase]. Yao xue xue bao = Acta pharmaceutica Sinica 20020401
The function of photosystem I. Quantum chemical insight into the role of tryptophan-quinone interactions. Biochemistry 20020305
Inhibitory effects of quinones on RNase H activity associated with HIV-1 reverse transcriptase. Phytotherapy research : PTR 20020301
Geranyl diphosphate:4-hydroxybenzoate geranyltransferase from Lithospermum erythrorhizon. Cloning and characterization of a ket enzyme in shikonin biosynthesis. The Journal of biological chemistry 20020222
Exploring the primary electron acceptor (QA)-site of the bacterial reaction center from Rhodobacter sphaeroides. Binding mode of vitamin K derivatives. European journal of biochemistry 20020201
Irreversible photo-oxidation of propranolol triggered by self-photogenerated singlet molecular oxygen. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20020201
Inhibition of Ca2+-activated and voltage-dependent K+ currents by 2-mercaptophenyl-1,4-naphthoquinone in pituitary GH3 cells: contribution to its antiproliferative effect. Life sciences 20020125
Antipruritic effects of 1,4-naphthoquinones and related compounds. Biological & pharmaceutical bulletin 20020101
[Respiratory activity and naphthoquinone synthesis in the fungus Fusarium decemcellulare exposed to oxidative stress]. Mikrobiologiia 20020101
Synthesis, electrochemical and spectral properties of some omega-N-quinonyl amino acids. Amino acids 20020101
Solubilization of a naphthoquinone derivative by hydroxypropyl-beta-cyclodextrin (HP-beta-CD) and polyvinylpyrrolidone (PVP-K30). The influence of PVP-K30 and pH on solubilizing effect of HP-beta-CD. Bollettino chimico farmaceutico 20020101
[Synthesis of triads based on deuteroporphyrin IX, naphthoquinone, and aromatic amino acids]. Bioorganicheskaia khimiia 20020101
Thermal analysis and spectroscopic characterization of interactions between a naphthoquinone derivative with HP-beta-CD or PVP. Pharmaceutical development and technology 20020101
Luminol as a probe to assess reactive oxygen species production from redox-cycling drugs in cultured hepatocytes. Toxicology mechanisms and methods 20020101
Discovery, total synthesis, HRV 3C-protease inhibitory activity, and structure-activity relationships of 2-methoxystypandrone and its analogues. Bioorganic & medicinal chemistry letters 20011217
Synthesis and biological studies of novel nucleoside phosphoramidate prodrugs. Journal of medicinal chemistry 20011206
Hydroxysesamone and 2,3-epoxysesamone from roots of Sesamum indicum. Phytochemistry 20011201
A new naphthoquinone from Pyrola japonica. Archives of pharmacal research 20011201
Interaction of camel lens zeta-crystallin with quinones: portrait of a substrate by fluorescence spectroscopy. Archives of biochemistry and biophysics 20011115
Recruitment of a foreign quinone into the A1 site of photosystem I. In vivo replacement of plastoquinone-9 by media-supplemented naphthoquinones in phylloquinone biosynthetic pathway mutants of Synechocystis sp. PCC 6803. The Journal of biological chemistry 20011026
Abiotic transformation of catechol and 1-naphthol in aqueous solution-influence of environmental factors. Water research 20011001
Spectrophotometric kinetic and determination of quinones and barbiturates. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20011001
Combinatorial screening of heterogeneous catalysis in selective oxidation of naphthalene by laser-induced fluorescence imaging. Analytical chemistry 20010915
Inactivation of rat cytochrome P450 2D enzyme by a further metabolite of 4-hydroxypropranolol, the major and active metabolite of propranolol. Biological & pharmaceutical bulletin 20010901
Bromination studies of the 2,3-dimethylnaphthazarin core allowing easy access to naphthazarin derivatives. The Journal of organic chemistry 20010810
Concerted action of DT-diaphorase and superoxide dismutase in preventing redox cycling of naphthoquinones: an evaluation. Free radical research 20010801
Caspase-3-mediated cleavage of the NF-kappa B subunit p65 at the NH2 terminus potentiates naphthoquinone analog-induced apoptosis. The Journal of biological chemistry 20010706
Association of quinone-induced platelet anti-aggregation with cytotoxicity. Toxicological sciences : an official journal of the Society of Toxicology 20010701
Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cells more effectively than ellagic acid and genistein in vitro. Anti-cancer drugs 20010601
Mutational analyses of cysteine residues of bovine dihydrodiol dehydrogenase 3. Biochimica et biophysica acta 20010505
New selective cytotoxic diterpenylquinones and diterpenylhydroquinones. Journal of medicinal chemistry 20010412
A novel dark-inducible protein, LeDI-2, and its involvement in root-specific secondary metabolism in Lithospermum erythrorhizon. Plant physiology 20010401
Effects of modulation of tissue activities of DT-diaphorase on the toxicity of 2,3-dimethyl-1,4-naphthoquinone to rats. Chemico-biological interactions 20010314
NAD(P)H:menadione oxidoreductase of the amitochondriate eukaryote Giardia lamblia: a simpler homologue of the vertebrate enzyme. Microbiology (Reading, England) 20010301
Selective nonpeptidic inhibitors of herpes simplex virus type 1 and human cytomegalovirus proteases. Biological & pharmaceutical bulletin 20010301
Production and characterisation of mucoadhesive nanosuspensions for the formulation of bupravaquone. International journal of pharmaceutics 20010219
2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity. Journal of medicinal chemistry 20010215
In vitro and in vivo Leishmanicidal activity of 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone (lapachol). Phytotherapy research : PTR 20010201
[Cytotoxicity of beta-lapachone, an naphthoquinone with possible therapeutic use]. Medicina 20010101
Multiple oxidative stress parameters are modulated in vitro by oxygenated polycyclic aromatic hydrocarbons identified in river sediments. Advances in experimental medicine and biology 20010101
A new naphthoquinone from Bombax malabaricum. Journal of Asian natural products research 20010101
Molecular modeling and 3D-QSAR studies in 2-aziridinyl-and 2,3-bis(aziridinyl)-1,4-naphthoquinonyl sulfonate and acylate derivatives as potential antimalarial agents. SAR and QSAR in environmental research 20010101
Kinetics of inhibition of human and rat dihydroorotate dehydrogenase by atovaquone, lawsone derivatives, brequinar sodium and polyporic acid. Chemico-biological interactions 20000103
2-chloro-3-substituted-1,4-naphthoquinone inactivators of human cytomegalovirus protease. Bioorganic & medicinal chemistry letters 19991004
Inhibitors of human immunodeficiency virus integrase. Proceedings of the National Academy of Sciences of the United States of America 19930315
Properties