(1R,4r)-4-((R)-1-aminoethyl)-N-(pyridin-4-yl)cyclohexanecarboxamide dihydrochloride
| Title | Journal |
|---|---|
| ROCK-dependent ATP5D modulation contributes to the protection of notoginsenoside NR1 against ischemia-reperfusion-induced myocardial injury. | American journal of physiology. Heart and circulatory physiology 20141215 |
| Erythropoietin promotes axonal regeneration after optic nerve crush in vivo by inhibition of RhoA/ROCK signaling pathway. | Neuropharmacology 20121101 |
| miRNAs can increase the efficiency of ex vivo platelet generation. | Annals of hematology 20121101 |
| The effect of hypercholesterolemia on carbachol-induced contractions of the detrusor smooth muscle in rats: increased role of L-type Ca2+ channels. | Naunyn-Schmiedeberg's archives of pharmacology 20121101 |
| High glucose enhances responsiveness of human airways smooth muscle via the Rho/ROCK pathway. | American journal of respiratory cell and molecular biology 20121001 |
| Cyclic compression-induced p38 activation and subsequent MMP13 expression requires Rho/ROCK activity in bovine cartilage explants. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20121001 |
| Bioengineered human IAS reconstructs with functional and molecular properties similar to intact IAS. | American journal of physiology. Gastrointestinal and liver physiology 20120915 |
| Stimulation of norepinephrine transporter function by fasudil, a Rho kinase inhibitor, in cultured bovine adrenal medullary cells. | Naunyn-Schmiedeberg's archives of pharmacology 20120901 |
| Aging impairs Ca2+ sensitization pathways in gallbladder smooth muscle. | Age (Dordrecht, Netherlands) 20120801 |
| Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity. | Molecular & cellular proteomics : MCP 20120801 |
| Soluble epoxide hydrolase: sex differences and role in endothelial cell survival. | Arteriosclerosis, thrombosis, and vascular biology 20120801 |
| ROCK1 feedback regulation of the upstream small GTPase RhoA. | Cellular signalling 20120701 |
| Atorvastatin inhibits myocardin expression in vascular smooth muscle cells. | Hypertension (Dallas, Tex. : 1979) 20120701 |
| Arsenite activates NFκB through induction of C-reactive protein. | Toxicology and applied pharmacology 20120615 |
| Pregnancy reduces RhoA/Rho kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat uterine artery. | American journal of physiology. Heart and circulatory physiology 20120615 |
| The role of Rho/Rho-kinase pathway in the expression of ICAM-1 by linoleic acid in human aortic endothelial cells. | Inflammation 20120601 |
| Possible Involvement of Sphingosine-1-Phosphate/G(i)/RhoA pathways in adherence of eosinophils to pulmonary endothelium. | Allergology international : official journal of the Japanese Society of Allergology 20120601 |
| Simvastatin attenuated cerebrovascular cell proliferation in the development of hypertension through Rho/Rho-kinase pathway. | Journal of cardiovascular pharmacology 20120601 |
| Role of sphingosine-1-phosphate inβ-adrenoceptor desensitization via Ca(2+) sensitization in airway smooth muscle. | Allergology international : official journal of the Japanese Society of Allergology 20120601 |
| The effect of Rho-associated protein kinase inhibitor on monkey Schlemm's canal endothelial cells. | Investigative ophthalmology & visual science 20120522 |
| Thrombin receptor regulates hematopoiesis and endothelial-to-hematopoietic transition. | Developmental cell 20120515 |
| Perspective on the role of P2X-purinoceptor activation in human vas deferens contractility. | Experimental physiology 20120501 |
| Rho kinase (ROK)-related proteins in human cavernous arteries: an immunohistochemical and functional approach. | The journal of sexual medicine 20120501 |
| The Rho kinase inhibitor SAR407899 potently inhibits endothelin-1-induced constriction of renal resistance arteries. | Journal of hypertension 20120501 |
| Functional role of muscarinic receptor subtypes in calcium sensitization and their contribution to rho-kinase and protein kinase C pathways in contraction of human detrusor smooth muscle. | Urology 20120501 |
| ROCKII Ser1366 phosphorylation reflects the activation status. | The Biochemical journal 20120401 |
| Obstruction enhances rho-kinase pathway and diminishes protein kinase C pathway in carbachol-induced calcium sensitization in contraction of α-toxin permeabilized guinea pig detrusor smooth muscle. | Neurourology and urodynamics 20120401 |
| Inhibition of actin dynamics during epithelial-to-mesenchymal transition. | Biochemical and biophysical research communications 20120309 |
| Astrocyte stellation, a process dependent on Rac1 is sustained by the regulated exocytosis of enlargeosomes. | Glia 20120301 |
| Simvastatin inhibits sphingosylphosphorylcholine-induced differentiation of human mesenchymal stem cells into smooth muscle cells. | Experimental & molecular medicine 20120227 |
| Progesterone enhances vascular endothelial cell migration via activation of focal adhesion kinase. | Journal of cellular and molecular medicine 20120201 |
| Regulatable stiffness in relaxed airway smooth muscle: a target for asthma treatment? | Journal of applied physiology (Bethesda, Md. : 1985) 20120201 |
| Gene pathway analysis of the mechanism by which the Rho-associated kinase inhibitor Y-27632 inhibits apoptosis in isolated thawed human embryonic stem cells. | Cryobiology 20120201 |
| Inhibition of Rho kinase by hydroxyfasudil attenuates brain edema after subarachnoid hemorrhage in rats. | Neurochemistry international 20120201 |
| Enucleation of human erythroblasts involves non-muscle myosin IIB. | Blood 20120126 |
| A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors. | Nature neuroscience 20120115 |
| Accelerated generation of human induced pluripotent stem cells with retroviral transduction and chemical inhibitors under physiological hypoxia. | Biochemical and biophysical research communications 20120113 |
| Resolving the challenge of measuring ligand binding to membrane proteins by combining analytical ultracentrifugation and light scattering photometry. | Journal of pharmaceutical sciences 20120101 |
| A possible mechanism of basic fibroblast growth factor-promoted scarless wound healing: the induction of myofibroblast apoptosis. | European journal of dermatology : EJD 20120101 |
| Effect of simvastatin on transforming growth factor beta-1-induced myofibroblast differentiation and collagen production in nasal polyp-derived fibroblasts. | American journal of rhinology & allergy 20120101 |
| RhoA: a therapeutic target for chronic myeloid leukemia. | Molecular cancer 20120101 |
| Impaired myogenic tone in isolated cerebral and coronary resistance arteries from the goto-kakizaki rat model of type 2 diabetes. | Journal of vascular research 20120101 |
| [Y-27632 induces calcium-independent glutamate release in rat brain synaptosomes by the mechanism which is distinct from exocytosis]. | Biofizika 20120101 |
| Different effect of Rho kinase inhibition on calcium signaling in rat isolated large and small arteries. | Journal of vascular research 20120101 |
| RhoA-ROCK-Myosin pathway regulates morphological plasticity of cultured olfactory ensheathing cells. | Experimental cell research 20111210 |
| Protective effects of dexpanthenol and y-27632 on stricture formation in a rat model of caustic esophageal injury. | The Journal of surgical research 20111201 |
| The suppression of myosin light chain (MLC) phosphorylation during the response to lipopolysaccharide (LPS): beneficial or detrimental to endothelial barrier? | Journal of cellular physiology 20111201 |
| Synthetic osteogenic growth peptide promotes differentiation of human bone marrow mesenchymal stem cells to osteoblasts via RhoA/ROCK pathway. | Molecular and cellular biochemistry 20111201 |
| Differential involvement of ezrin/radixin/moesin proteins in sphingosine 1-phosphate-induced human pulmonary endothelial cell barrier enhancement. | Cellular signalling 20111201 |
| Depigmenting action of platycodin D depends on the cAMP/Rho-dependent signalling pathway. | Experimental dermatology 20111201 |
| Wnt-signaling mediates the anti-adipogenic action of lysophosphatidic acid through cross talking with the Rho/Rho associated kinase (ROCK) pathway. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20111201 |
| Synchronous phosphorylation of CPI-17 and MYPT1 is essential for inducing Ca(2+) sensitization in intestinal smooth muscle. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20111201 |
| Osteopontin is involved in urotensin II-induced migration of rat aortic adventitial fibroblasts. | Peptides 20111201 |
| LPA(1) -induced migration requires nonmuscle myosin II light chain phosphorylation in breast cancer cells. | Journal of cellular physiology 20111101 |
| Electrically guiding migration of human induced pluripotent stem cells. | Stem cell reviews 20111101 |
| Role of RhoA and its effectors ROCK and mDia1 in the modulation of deformation-induced FAK, ERK, p38, and MLC motogenic signals in human Caco-2 intestinal epithelial cells. | American journal of physiology. Cell physiology 20111101 |
| The Rho kinase inhibitor Y-27632 increases erythrocyte deformability and low oxygen tension-induced ATP release. | American journal of physiology. Heart and circulatory physiology 20111101 |
| Vascular smooth muscle cell migration induced by domains of thrombospondin-1 is differentially regulated. | American journal of surgery 20111101 |
| Amelioration of albuminuria in ROCK1 knockout mice with streptozotocin-induced diabetic kidney disease. | American journal of nephrology 20111101 |
| RhoA activation and effect of Rho-kinase inhibitor in the development of retinal neovascularization in a mouse model of oxygen-induced retinopathy. | Current eye research 20111101 |
| Dynamic ordering of nuclei in syncytial embryos: a quantitative analysis of the role of cytoskeletal networks. | Integrative biology : quantitative biosciences from nano to macro 20111101 |
| Rac-dependent doubling of HeLa cell area and impairment of cell migration and cell cycle by compounds from Iris germanica. | Protoplasma 20111001 |
| Protein prenylation contributes to the effects of LPS on EFS-induced responses in human isolated bronchi. | American journal of respiratory cell and molecular biology 20111001 |
| Similar hydrodynamic and morphological changes in the aqueous humor outflow pathway after washout and Y27632 treatment in monkey eyes. | Experimental eye research 20111001 |
| Rho kinase-related proteins in human vaginal arteries: an immunohistochemical and functional study. | The journal of sexual medicine 20111001 |
| Rho-kinase inhibition ameliorates peritoneal fibrosis and angiogenesis in a rat model of peritoneal sclerosis. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110901 |
| In vitro differentiation of rat embryonic stem cells into functional cardiomyocytes. | Cell research 20110901 |
| Epithelial inducible nitric oxide synthase causes bacterial translocation by impairment of enterocytic tight junctions via intracellular signals of Rho-associated kinase and protein kinase C zeta. | Critical care medicine 20110901 |
| ROCK inhibition prevents fetal serum-induced alteration in structure and function of organ-cultured mesenteric artery. | Journal of muscle research and cell motility 20110901 |
| TGF-β2 reduces nitric oxide synthase mRNA through a ROCK-dependent pathway in airway epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20110901 |
| [Rho-kinase inhibitors]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20110901 |
| Rho kinase as a therapeutic target in cardiovascular disease. | Future cardiology 20110901 |
| Thrombin induces MCP-1 expression through Rho-kinase and subsequent p38MAPK/NF-κB signaling pathway activation in vascular endothelial cells. | Biochemical and biophysical research communications 20110812 |
| Aldosterone induction of hepatic stellate cell contraction through activation of RhoA/ROCK-2 signaling pathway. | Regulatory peptides 20110808 |
| A practical synthesis of Rho-Kinase inhibitor Y-27632 and fluoro derivatives and their evaluation in human pluripotent stem cells. | Organic & biomolecular chemistry 20110807 |
| Increased liver uptake and reduced hepatic stellate cell activation with a cell-specific conjugate of the Rho-kinase inhibitor Y27632. | Pharmaceutical research 20110801 |
| Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells. | American journal of physiology. Gastrointestinal and liver physiology 20110801 |
| Protective effects of Y-27632 on hypoxia/reoxygenation-induced intestinal injury in newborn rats. | Journal of pediatric surgery 20110801 |
| [Activation of Rho-kinase pathway is involved in angiotensin II-induced contraction of human airway smooth muscle cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20110801 |
| Functional, morphological and molecular characterization of bladder dysfunction in streptozotocin-induced diabetic mice: evidence of a role for L-type voltage-operated Ca2+ channels. | British journal of pharmacology 20110701 |
| Regulation of V-ATPase recycling via a RhoA- and ROCKII-dependent pathway in epididymal clear cells. | American journal of physiology. Cell physiology 20110701 |
| Integrin α3 blockade enhances microtopographical down-regulation of α-smooth muscle actin: role of microtopography in ECM regulation. | Integrative biology : quantitative biosciences from nano to macro 20110701 |
| Effects of Rho-associated protein kinase inhibitors Y-27632 and Y-39983 on isolated rabbit ciliary arteries. | Japanese journal of ophthalmology 20110701 |
| Contribution of Rho-kinase to membrane excitability of murine colonic smooth muscle. | British journal of pharmacology 20110601 |
| Impaired Ca2+ handling in penile arteries from prediabetic Zucker rats: involvement of Rho kinase. | American journal of physiology. Heart and circulatory physiology 20110601 |
| Reduction of fibrogenesis by selective delivery of a Rho kinase inhibitor to hepatic stellate cells in mice. | The Journal of pharmacology and experimental therapeutics 20110601 |
| Increased contractility of hepatic stellate cells in cirrhosis is mediated by enhanced Ca2+-dependent and Ca2+-sensitization pathways. | American journal of physiology. Gastrointestinal and liver physiology 20110601 |
| Rho kinase inhibitors stimulate the migration of human cultured osteoblastic cells by regulating actomyosin activity. | Cellular & molecular biology letters 20110601 |
| Sevoflurane inhibits angiotensin II-induced Rho kinase-mediated contraction of vascular smooth muscle from spontaneously hypertensive rat. | Journal of anesthesia 20110601 |
| Chelerythrine perturbs lamellar actomyosin filaments by selective inhibition of myotonic dystrophy kinase-related Cdc42-binding kinase. | FEBS letters 20110506 |
| Differential role of Rho GTPases in intestinal epithelial barrier regulation in vitro. | Journal of cellular physiology 20110501 |
| Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway. | American journal of physiology. Cell physiology 20110501 |
| Rho signaling pathway and apical constriction in the early lens placode. | Genesis (New York, N.Y. : 2000) 20110501 |
| Regulation of MT1-MMP and MMP-2 by leptin in cardiac fibroblasts involves Rho/ROCK-dependent actin cytoskeletal reorganization and leads to enhanced cell migration. | Endocrinology 20110501 |
| [Production of connective tissue growth factor by angiotensin II in human embryonic lung fibroblast via RhoA-ROCK pathway]. | Zhonghua yi xue za zhi 20110426 |
| Ca2+ sensitization and PKC contribute to exercise training-enhanced contractility in porcine collateral-dependent coronary arteries. | American journal of physiology. Heart and circulatory physiology 20110401 |
| Phospholipase Cdelta3 regulates RhoA/Rho kinase signaling and neurite outgrowth. | The Journal of biological chemistry 20110311 |
| LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress. | Cell stem cell 20110304 |
| Cryopreservation of human embryonic stem cells derived-cardiomyocytes induced by BMP2 in serum-free condition. | Reproductive sciences (Thousand Oaks, Calif.) 20110301 |
| ROCK and cAMP promote lymphatic endothelial cell barrier integrity and modulate histamine and thrombin-induced barrier dysfunction. | Lymphatic research and biology 20110301 |
| Advanced glycation end products induce moesin phosphorylation in murine brain endothelium. | Brain research 20110210 |
| Rho-kinase signalling regulates trypsinogen activation and tissue damage in severe acute pancreatitis. | British journal of pharmacology 20110201 |
| Effects of ischemic preconditioning on vascular reactivity and calcium sensitivity after hemorrhagic shock and their relationship to the RhoA–Rho-kinase pathway in rats. | Journal of cardiovascular pharmacology 20110201 |
| Characteristics of myogenic reactivity in isolated rat mesenteric veins. | American journal of physiology. Regulatory, integrative and comparative physiology 20110201 |
| The Rho kinase pathway regulates mouse adult neural precursor cell migration. | Stem cells (Dayton, Ohio) 20110201 |
| Thromboxane A2 induces contraction of human prostate smooth muscle by Rho kinase- and calmodulin-dependent mechanisms. | European journal of pharmacology 20110115 |
| Rho-kinase inhibitor upregulates migration by altering focal adhesion formation via the Akt pathway in colon cancer cells. | European journal of pharmacology 20110110 |
| Rho-associated kinase plays a role in rabbit urethral smooth muscle contraction, but not via enhanced myosin light chain phosphorylation. | American journal of physiology. Renal physiology 20110101 |
| Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110101 |
| RhoA/Rho kinase pathway contributes to the pathogenesis of thermal hyperalgesia in diabetic mice. | Pain 20110101 |
| Inhibition of Rho-kinase abrogates migration of human transitional cell carcinoma cells: results of an in vitro study. | Urologia internationalis 20110101 |
| The effect of lysophosphatidic acid and Rho-associated kinase patterning on adhesion of dental pulp cells. | International endodontic journal 20110101 |
| ρ-Kinase inhibition reduces early microvascular leukocyte accumulation in the rat kidney following ischemia-reperfusion injury: roles of nitric oxide and blood flow. | Nephron. Experimental nephrology 20110101 |
| Geranylgeranyl-pyrophosphate regulates secretion of pentraxin 3 and monocyte chemoattractant protein-1 from rheumatoid fibroblast-like synoviocytes in distinct manners. | Clinical and experimental rheumatology 20110101 |
| ROCK inhibitor Y-27632 suppresses dissociation-induced apoptosis of murine prostate stem/progenitor cells and increases their cloning efficiency. | PloS one 20110101 |
| Actomyosin-dependent cortical dynamics contributes to the prophase force-balance in the early Drosophila embryo. | PloS one 20110101 |
| Na+/Ca2+ exchanger inhibitors inhibit neurite outgrowth in PC12 cells. | Journal of pharmacological sciences 20110101 |
| [The effect of Rho-kinase inhibition depends on the nature of factors that modify endothelial permeability]. | Tsitologiia 20110101 |
| Inhibition of Rho-associated coiled-coil containing protein kinase enhances the activation of epidermal growth factor receptor in pancreatic cancer cells. | Molecular cancer 20110101 |
| Regulation of retinoschisin secretion in Weri-Rb1 cells by the F-actin and microtubule cytoskeleton. | PloS one 20110101 |
| Rho-Rho kinase pathway in the actomyosin contraction and cell-matrix adhesion in immortalized human trabecular meshwork cells. | Molecular vision 20110101 |
| Homocysteine induces phosphatidylserine exposure in cardiomyocytes through inhibition of Rho kinase and flippase activity. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20110101 |
| Co-crystal structures of inhibitors with MRCKβ, a key regulator of tumor cell invasion. | PloS one 20110101 |
| Decreases in CD31 and CD47 levels on the cell surface during etoposide-induced Jurkat cell apoptosis. | Biological & pharmaceutical bulletin 20110101 |
| Inhibition of Rho kinase regulates specification of early differentiation events in P19 embryonal carcinoma stem cells. | PloS one 20110101 |
| Lipid A decreases human erythrocytes deformability by increasing intracellular Ca(2+): effects of verapamil, staurosporine and the rho-kinase inhibitor Y-27632. | Clinical hemorheology and microcirculation 20110101 |
| Osteoclastogenic activity and RANKL expression are inhibited in osteoblastic cells expressing constitutively active Gα(12) or constitutively active RhoA. | Journal of cellular biochemistry 20101215 |
| Ouabain-induced apoptosis and Rho kinase: a novel caspase-2 cleavage site and fragment of Rock-2. | Apoptosis : an international journal on programmed cell death 20101201 |
| Potentiation of nerve growth factor-induced neurite outgrowth by the ROCK inhibitor Y-27632: a possible role of IP₃ receptors. | European journal of pharmacology 20101201 |
| Rescue treatment with a Rho-kinase inhibitor normalizes right ventricular function and reverses remodeling in juvenile rats with chronic pulmonary hypertension. | American journal of physiology. Heart and circulatory physiology 20101201 |
| Identification and functional implication of a Rho kinase-dependent moesin-EBP50 interaction in noradrenaline-stimulated artery. | American journal of physiology. Cell physiology 20101201 |
| Effect of the Rho kinase inhibitor Y-27632 on the proteome of hearts with ischemia-reperfusion injury. | Proteomics 20101201 |
| Modulation of the Rho/ROCK pathway in heart and lung after thorax irradiation reveals targets to improve normal tissue toxicity. | Current drug targets 20101101 |
| Inhibition of Rho-ROCK signaling induces apoptotic and non-apoptotic PS exposure in cardiomyocytes via inhibition of flippase. | Journal of molecular and cellular cardiology 20101101 |
| Pharmacological inhibition of Rho-kinase (ROCK) signaling enhances cisplatin resistance in neuroblastoma cells. | International journal of oncology 20101101 |
| The origin recognition complex subunit, ORC3, is developmentally regulated and supports the expression of biochemical markers of neuronal maturation in cultured cerebellar granule cells. | Brain research 20101028 |
| Polarization and migration of hematopoietic stem and progenitor cells rely on the RhoA/ROCK I pathway and an active reorganization of the microtubule network. | The Journal of biological chemistry 20101008 |
| Acute and chronic alcohol exposure impair the phagocytosis of apoptotic cells and enhance the pulmonary inflammatory response. | Alcoholism, clinical and experimental research 20101001 |
| NF-κB as a common signaling pathway in ganglioside-induced autophagic cell death and activation of astrocytes. | Journal of neuroimmunology 20100914 |
| Balamuthia mandrillaris: role of galactose in encystment and identification of potential inhibitory targets. | Experimental parasitology 20100901 |
| Dissecting the molecular architecture of integrin adhesion sites by cryo-electron tomography. | Nature cell biology 20100901 |
| Lovastatin inhibits EGFR dimerization and AKT activation in squamous cell carcinoma cells: potential regulation by targeting rho proteins. | Oncogene 20100819 |
| Lysophosphatidic acid signals through multiple receptors in osteoclasts to elevate cytosolic calcium concentration, evoke retraction, and promote cell survival. | The Journal of biological chemistry 20100813 |
| The mechanism by which RhoA regulates vascular reactivity after hemorrhagic shock in rats. | American journal of physiology. Heart and circulatory physiology 20100801 |
| Effect of low concentrations of hydrogen peroxide on the contractile responses of rat detrusor smooth muscle strips. | European journal of pharmacology 20100725 |
| Rho kinase activation and ROS production contributes to the cooling enhanced contraction in cutaneous equine digital veins. | Journal of applied physiology (Bethesda, Md. : 1985) 20100701 |
| Analysis of responses to the Rho-kinase inhibitor Y-27632 in the pulmonary and systemic vascular bed of the rat. | American journal of physiology. Heart and circulatory physiology 20100701 |
| Acute hyperglycemia induces rapid, reversible increases in glomerular permeability in nondiabetic rats. | American journal of physiology. Renal physiology 20100601 |
| Substituted 2H-isoquinolin-1-one as potent Rho-Kinase inhibitors. Part 1: Hit-to-lead account. | Bioorganic & medicinal chemistry letters 20100601 |
| Enhancement of cell recovery for dissociated human embryonic stem cells after cryopreservation. | Biotechnology progress 20100501 |
| RhoA-Rho kinase signaling mediates endothelium- and endoperoxide-dependent contractile activities characteristic of hypertensive vascular dysfunction. | American journal of physiology. Heart and circulatory physiology 20100501 |
| Stimulatory effect of Rho-associated coiled-coil kinase (ROCK) inhibitor on revivability of in vitro-produced bovine blastocysts after vitrification. | Theriogenology 20100501 |
| [Effects of simvastatin on proliferation and transition of phenotype in PDGF-BB-induced pulmonary artery smooth muscle cells]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100501 |
| Rho-kinase inhibitor attenuates cholestasis-induced CXC chemokine formation, leukocyte recruitment, and hepatocellular damage in the liver. | The Journal of surgical research 20100401 |
| Roles of lysophosphatidic acid and the Rho-associated kinase pathway in the migration of dental pulp cells. | Experimental cell research 20100401 |
| Up-regulation of the RhoA/Rho-kinase signaling pathway in corpus cavernosum from endothelial nitric-oxide synthase (NOS), but not neuronal NOS, null mice. | The Journal of pharmacology and experimental therapeutics 20100401 |
| Rho-kinase limits FGF-2-stimulated VEGF release in osteoblasts. | Bone 20100401 |
| Kupffer cell activation by hydrogen peroxide: a new mechanism of portal pressure increase. | Shock (Augusta, Ga.) 20100401 |
| Rho kinase inhibitor y27632 alters the balance between pluripotency and early differentiation events in human embryonic stem cells. | Current stem cell research & therapy 20100301 |
| Presence of a ROCK inhibitor in extracellular matrix supports more undifferentiated growth of feeder-free human embryonic and induced pluripotent stem cells upon passaging. | Stem cell reviews 20100301 |
| Rho kinase inhibitor Y-27632 facilitates recovery from experimental peripheral neuropathy induced by anti-cancer drug cisplatin. | Neurotoxicology 20100301 |
| Integrins stimulate E-cadherin-mediated intercellular adhesion by regulating Src-kinase activation and actomyosin contractility. | Journal of cell science 20100301 |
| ROCK inhibition facilitates tissue reconstitution from embryonic kidney cell suspensions. | Kidney international 20100301 |
| Protective effects of Y-27632 on acute dichlorvos poisoning in rats. | The American journal of emergency medicine 20100301 |
| Rho kinase inhibition protects CA1 cells in organotypic hippocampal slices during in vitro ischemia. | Brain research 20100226 |
| N-acetylcysteine inhibits RhoA and promotes apoptotic cell clearance during intense lung inflammation. | American journal of respiratory and critical care medicine 20100215 |
| Effects of rho-kinase inhibition on pulmonary hypertension, lung growth, and structure in neonatal rats chronically exposed to hypoxia. | Pediatric research 20100201 |
| Endothelial P2Y2 receptor regulates LPS-induced neutrophil transendothelial migration in vitro. | Molecular immunology 20100201 |
| Dynamic regulation of ROCK in tumor cells controls CXCR4-driven adhesion events. | Journal of cell science 20100201 |
| Features of distinct contractions induced with a high and a low concentration of KCl, noradrenaline, and histamine in swine lingual artery. | Naunyn-Schmiedeberg's archives of pharmacology 20100201 |
| Promigratory and procontractile growth factor environments differentially regulate cell morphogenesis. | Experimental cell research 20100115 |
| The suppressive effect of Rho kinase inhibitor, Y-27632, on oncogenic Ras/RhoA induced invasion/migration of human bladder cancer TSGH cells. | Chemico-biological interactions 20100105 |
| Interactive role of protein phosphatase 2A and protein kinase Calpha in the stretch-induced triphosphorylation of myosin light chain in canine cerebral artery. | Journal of vascular research 20100101 |
| Alginate microcapsule for propagation and directed differentiation of hESCs to definitive endoderm. | Biomaterials 20100101 |
| New approaches to the treatment of pulmonary hypertension: from bench to bedside. | Cardiology in review 20100101 |
| Rho kinases regulate the renewal and neural differentiation of embryonic stem cells in a cell plating density-dependent manner. | PloS one 20100101 |
| Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL). | Cellular immunology 20100101 |
| Adult rats are more sensitive to the vascular effects induced by hyperhomocysteinemia than young rats. | Vascular pharmacology 20100101 |
| Modification of the detrimental effect of TNF-α on human endothelial progenitor cells by fasudil and Y27632. | Journal of biochemical and molecular toxicology 20100101 |
| The ROCK inhibitor Y-27632 improves recovery of human embryonic stem cells after fluorescence-activated cell sorting with multiple cell surface markers. | PloS one 20100101 |
| Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells. | Molecular and cellular neurosciences 20091201 |
| Nitric oxide inhibits endothelin-1-induced neonatal cardiomyocyte hypertrophy via a RhoA-ROCK-dependent pathway. | Journal of molecular and cellular cardiology 20091201 |
| Involvement of Rho-kinase in tumor necrosis factor-alpha-induced interleukin-6 release from C6 glioma cells. | Neurochemistry international 20091101 |
| Involvement of Rho-kinase in prostaglandin E(1)-stimulated VEGF synthesis through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblast-like MC3T3-E1 cells. | Prostaglandins & other lipid mediators 20091101 |
| Inhibition of geranylgeranyltransferase inhibits bronchial smooth muscle hyperresponsiveness in mice. | American journal of physiology. Lung cellular and molecular physiology 20091101 |
| ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK. | The Journal of biological chemistry 20091023 |
| Substrate specificity and inhibitors of LRRK2, a protein kinase mutated in Parkinson's disease. | The Biochemical journal 20091023 |
| Comparative screening of glial cell types reveals extracellular matrix that inhibits retinal axon growth in a chondroitinase ABC-resistant fashion. | Glia 20091001 |
| Suppression of hepatitis C virus replication by protein kinase C-related kinase 2 inhibitors that block phosphorylation of viral RNA polymerase. | Journal of viral hepatitis 20091001 |
| ROCK inhibition promotes adult retinal ganglion cell neurite outgrowth only in the presence of growth promoting factors. | Molecular and cellular neurosciences 20091001 |
| Calcium-dependent and calcium-independent inhibition of contraction by cGMP/cGKI in intestinal smooth muscle. | American journal of physiology. Gastrointestinal and liver physiology 20091001 |
| In vitro differentiation of retinal cells from human pluripotent stem cells by small-molecule induction. | Journal of cell science 20090901 |
| Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies. | British journal of cancer 20090901 |
| Rho-mediated regulation of TGF-beta1- and FGF-2-induced activation of corneal stromal keratocytes. | Investigative ophthalmology & visual science 20090801 |
| Cyclic mechanical stress and trabecular meshwork cell contractility. | Investigative ophthalmology & visual science 20090801 |
| Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor. | Investigative ophthalmology & visual science 20090801 |
| Carbohydrate analysis of Acanthamoeba castellanii. | Experimental parasitology 20090801 |
| Impaired cAMP and Rac 1 signaling contribute to TNF-alpha-induced endothelial barrier breakdown in microvascular endothelium. | Microcirculation (New York, N.Y. : 1994) 20090801 |
| Rho-kinase inhibitors Y-27632 and fasudil prevent agonist-induced vasospasm in human radial artery. | Canadian journal of physiology and pharmacology 20090801 |
| Rho GTPase signaling and PTH 3-34, but not PTH 1-34, maintain the actin cytoskeleton and antagonize bisphosphonate effects in mouse osteoblastic MC3T3-E1 cells. | Bone 20090701 |
| Localization of diacylglycerol kinase epsilon on stress fibers in vascular smooth muscle cells. | Cell and tissue research 20090701 |
| Involvement of Rho-kinase in sphingosine 1-phosphate-stimulated HSP27 induction in osteoblasts. | International journal of molecular medicine 20090701 |
| Lysophosphatidylcholine induces glial cell activation: role of rho kinase. | Glia 20090601 |
| The Rho-kinase inhibitor Y-27632 inhibits cholestasis-induced platelet interactions in the hepatic microcirculation. | Microvascular research 20090601 |
| Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090601 |
| Rho kinase inhibitor Y-27632 down-regulates norepinephrine synthesis and release in PC12 cells. | Basic & clinical pharmacology & toxicology 20090601 |
| Time-dependent phenotypic and contractile changes of pulmonary artery in chronic hypoxia-induced pulmonary hypertension. | Journal of pharmacological sciences 20090601 |
| Role of the Rho-ROCK (Rho-associated kinase) signaling pathway in the regulation of pancreatic beta-cell function. | Endocrinology 20090501 |
| Rho kinase inhibitors prevent endothelium-dependent contractions in the rat aorta. | The Journal of pharmacology and experimental therapeutics 20090501 |
| Rho kinase inhibition attenuates LPS-induced renal failure in mice in part by attenuation of NF-kappaB p65 signaling. | American journal of physiology. Renal physiology 20090501 |
| A rapid, PPAR-gamma-dependent effect of pioglitazone on the phosphorylation of MYPT. | American journal of physiology. Cell physiology 20090501 |
| The Rho-A/Rho-kinase pathway is up-regulated but remains inhibited by cyclic guanosine monophosphate-dependent mechanisms during endotoxemia in small mesenteric arteries. | Critical care medicine 20090501 |
| Vascular dysfunction in septic shock--any ROCKing news? | Critical care medicine 20090501 |
| ROCKs are expressed in brain tumors and are required for glioma-cell migration on myelinated axons. | Glia 20090401 |
| Roles of focal adhesions and fibronectin-mediated cohesion in proliferation of confluent fibroblasts. | Journal of cellular physiology 20090401 |
| Rho GTPases in hepatocellular carcinoma. | Biochimica et biophysica acta 20090401 |
| Rho-kinase-mediated suppression of KDR current in cerebral arteries requires an intact actin cytoskeleton. | American journal of physiology. Heart and circulatory physiology 20090401 |
| Participation of Rho-associated kinase in electrical stimulated and acetylcholine-induced contraction of feline esophageal smooth muscle. | European journal of pharmacology 20090401 |
| Y27632, a Rho-activated kinase inhibitor, normalizes dysregulation in alpha1-adrenergic receptor-induced contraction of Lyon hypertensive rat artery smooth muscle. | Fundamental & clinical pharmacology 20090401 |
| Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus. | European journal of pharmacology 20090315 |
| The role of lysophosphatidic acid receptor (LPA1) in the oxygen-induced retinal ganglion cell degeneration. | Investigative ophthalmology & visual science 20090301 |
| ROCK inhibitor improves survival of cryopreserved serum/feeder-free single human embryonic stem cells. | Human reproduction (Oxford, England) 20090301 |
| Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca(2+) sensitization. | Free radical biology & medicine 20090301 |
| Erectile function in two-kidney, one-clip hypertensive rats is maintained by a potential increase in nitric oxide production. | The journal of sexual medicine 20090301 |
| Cardioprotective effects of pitavastatin on cardiac performance and remodeling in failing rat hearts. | American journal of hypertension 20090201 |
| Role of protease-activated receptor-1 in endothelial nitric oxide synthase-Thr495 phosphorylation. | Experimental biology and medicine (Maywood, N.J.) 20090201 |
| Role of Ca2+ mobilization and Ca2+ sensitization in 8-iso-PGF 2 alpha-induced contraction in airway smooth muscle. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20090201 |
| EphA1 interacts with integrin-linked kinase and regulates cell morphology and motility. | Journal of cell science 20090115 |
| Lipocalin-2 is an autocrine mediator of reactive astrocytosis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090107 |
| ROCK-regulated cytoskeletal dynamics participate in the inhibitory effect of melatonin on cancer cell migration. | Journal of pineal research 20090101 |
| Adreno-muscarinic synergy in the bladder trigone: calcium-dependent and -independent mechanisms. | Cell calcium 20090101 |
| The small GTPase Rho mediates articular chondrocyte phenotype and morphology in response to interleukin-1alpha and insulin-like growth factor-I. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20090101 |
| Serofendic acid promotes stellation induced by cAMP and cGMP analogs in cultured cortical astrocytes. | Journal of pharmacological sciences 20090101 |
| Possible mechanisms underlying statin-induced skeletal muscle toxicity in L6 fibroblasts and in rats. | Journal of pharmacological sciences 20090101 |
| Modulation of human uterine smooth muscle cell collagen contractility by thrombin, Y-27632, TNF alpha and indomethacin. | Reproductive biology and endocrinology : RB&E 20090101 |
| Expression of RhoA mRNA and activated RhoA in urothelium and smooth muscle, and effects of a Rho-kinase inhibitor on contraction of the porcine urinary bladder. | Neurourology and urodynamics 20090101 |
| Obstruction alters muscarinic receptor-coupled RhoA/Rho-kinase pathway in the urinary bladder of the rat. | Neurourology and urodynamics 20090101 |
| In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue. | PloS one 20090101 |
| Signaling through Rho GTPase pathway as viable drug target. | Current medicinal chemistry 20090101 |
| Contractility of diabetic human corpus cavernosum smooth muscle in response to serotonin mediated via Rho-kinase. | Pharmacology 20090101 |
| Role of Rho/Rho-kinase and NO/cGMP signaling pathways in vascular function prior to atherosclerosis. | Journal of atherosclerosis and thrombosis 20090101 |
| Y-27632 enhances differentiation of blastocyst like cystic human embryoid bodies to endocrinologically active trophoblast cells on a biomimetic platform. | Journal of biomedical science 20090101 |
| Rearrangements of the actin cytoskeleton and E-cadherin-based adherens junctions caused by neoplasic transformation change cell-cell interactions. | PloS one 20090101 |
| Concomitant inhibition of prolyl hydroxylases and ROCK initiates differentiation of mesenchymal stem cells and PC12 towards the neuronal lineage. | Biochemical and biophysical research communications 20081212 |
| Aldosterone induces myofibroblastic transdifferentiation and collagen gene expression through the Rho-kinase dependent signaling pathway in rat mesangial cells. | Experimental cell research 20081210 |
| The anandamide analog, Met-F-AEA, controls human breast cancer cell migration via the RHOA/RHO kinase signaling pathway. | Endocrine-related cancer 20081201 |
| Role of src-family kinases in hypoxic vasoconstriction of rat pulmonary artery. | Cardiovascular research 20081201 |
| Notch3 is a major regulator of vascular tone in cerebral and tail resistance arteries. | Arteriosclerosis, thrombosis, and vascular biology 20081201 |
| The ROCK inhibitor Y-27632 enhances the survival rate of human embryonic stem cells following cryopreservation. | Stem cells and development 20081201 |
| Y-27632 augments the isoflurane-induced relaxation of bronchial smooth muscle in rats. | Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20081201 |
| Apolipoprotein(a), through its strong lysine-binding site in KIV(10'), mediates increased endothelial cell contraction and permeability via a Rho/Rho kinase/MYPT1-dependent pathway. | The Journal of biological chemistry 20081107 |
| Activation of Rho-kinase in the brainstem enhances sympathetic drive in mice with heart failure. | Autonomic neuroscience : basic & clinical 20081103 |
| Dual pathway activated by tert-butyl hydroperoxide in human airway anion secretion. | The Journal of pharmacology and experimental therapeutics 20081101 |
| Rho-associated kinase inhibitor Y-27632 promotes survival of cynomolgus monkey embryonic stem cells. | Molecular human reproduction 20081101 |
| Antiinflammatory effect of Rho kinase blockade via inhibition of NF-kappaB activation in rheumatoid arthritis. | Arthritis and rheumatism 20081101 |
| Identification of the Rock-dependent transcriptome in rodent fibroblasts. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20081101 |
| Rho/ROCK/actin signaling regulates membrane androgen receptor induced apoptosis in prostate cancer cells. | Experimental cell research 20081015 |
| Demonstration of elevation and localization of Rho-kinase activity in the brain of a rat model of cerebral infarction. | European journal of pharmacology 20081010 |
| Calcium sensitization in human esophageal muscle: role for RhoA kinase in maintenance of lower esophageal sphincter tone. | The Journal of pharmacology and experimental therapeutics 20081001 |
| Effects of a selective Rho-kinase inhibitor Y-27632 on oxidative stress parameters in acute dichlorvos poisoning in rats. | Cell biochemistry and function 20081001 |
| Novel interactions between the 5-HT transporter, 5-HT1B receptors and Rho kinase in vivo and in pulmonary fibroblasts. | British journal of pharmacology 20081001 |
| RhoA silencing reverts the resistance to doxorubicin in human colon cancer cells. | Molecular cancer research : MCR 20081001 |
| [Human pluripotent stem cell and neural differentiation]. | Brain and nerve = Shinkei kenkyu no shinpo 20081001 |
| Detection of myosin light chain phosphorylation--a cell-based assay for screening Rho-kinase inhibitors. | Biochemical and biophysical research communications 20080919 |
| Role of RhoA in activity-dependent cortical axon branching. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910 |
| Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice. | British journal of pharmacology 20080901 |
| Regulation of polarity in cells devoid of actin bundle system after treatment with inhibitors of myosin II activity. | Cell motility and the cytoskeleton 20080901 |
| Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expression. | Pharmacogenetics and genomics 20080901 |
| H89 (N-[2-(p-bromocinnamylamino)ethyl]-5-isoquinolinesulfonamide) induces reduction of myosin regulatory light chain phosphorylation and inhibits cell proliferation. | European journal of pharmacology 20080820 |
| Effects of endothelin-1 on calcium-independent contraction of bovine trabecular meshwork. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080801 |
| Rotenone-induced toxicity is mediated by Rho-GTPases in hippocampal neurons. | Toxicological sciences : an official journal of the Society of Toxicology 20080801 |
| Rho kinases regulate corneal epithelial wound healing. | American journal of physiology. Cell physiology 20080801 |
| Myosin light chain kinase activation and calcium sensitization in smooth muscle in vivo. | American journal of physiology. Cell physiology 20080801 |
| High glucose-induced upregulation of Rho/Rho-kinase via platelet-derived growth factor receptor-beta increases migration of aortic smooth muscle cells. | Journal of molecular and cellular cardiology 20080801 |
| Rho-kinase signalling mediates endotoxin hypersensitivity after partial hepatectomy. | The British journal of surgery 20080801 |
| Rho-associated kinases are crucial for myofibroblast differentiation and production of extracellular matrix in scleroderma fibroblasts. | Arthritis and rheumatism 20080801 |
| The inhaled Rho kinase inhibitor Y-27632 protects against allergen-induced acute bronchoconstriction, airway hyperresponsiveness, and inflammation. | American journal of physiology. Lung cellular and molecular physiology 20080701 |
| Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants. | Neurotoxicology 20080701 |
| Adenosine-oligoarginine conjugate, a novel bisubstrate inhibitor, effectively dissociates the actin cytoskeleton. | The FEBS journal 20080701 |
| Possible involvement of Rho-kinase in aldosterone-induced vascular smooth muscle cell remodeling. | Hypertension research : official journal of the Japanese Society of Hypertension 20080701 |
| Rho-kinase inhibitors augment the inhibitory effect of propofol on rat bronchial smooth muscle contraction. | Anesthesia and analgesia 20080601 |
| Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells. | Molecular cancer therapeutics 20080601 |
| [Optic nerve regeneration in adult mammals]. | Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20080601 |
| Melatonin restores impaired contractility in aged guinea pig urinary bladder. | Journal of pineal research 20080501 |
| Contractile changes of the clitoral cavernous smooth muscle in female rabbits with experimentally induced overactive bladder. | The journal of sexual medicine 20080501 |
| Prolactin stimulates transepithelial calcium transport and modulates paracellular permselectivity in Caco-2 monolayer: mediation by PKC and ROCK pathways. | American journal of physiology. Cell physiology 20080501 |
| Effects of atorvastatin and pravastatin on signal transduction related to glucose uptake in 3T3L1 adipocytes. | Journal of pharmacological sciences 20080501 |
| High glucose increases phosphocofilin via phosphorylation of LIM kinase due to Rho/Rho kinase activation in cultured pig proximal tubular epithelial cells. | Diabetes research and clinical practice 20080401 |
| Low intensity pulsed ultrasound accelerates macrophage phagocytosis by a pathway that requires actin polymerization, Rho, and Src/MAPKs activity. | Cellular signalling 20080401 |
| Rho kinase is involved in Ca2+ entry of rat penile small arteries. | American journal of physiology. Heart and circulatory physiology 20080401 |
| Beneficial effects of the Rho kinase inhibitor Y27632 in murine puromycin aminonucleoside nephrosis. | Kidney & blood pressure research 20080401 |
| Characterizations of sphingosylphosphorylcholine-induced scratching responses in ICR mice using naltrexon, capsaicin, ketotifen and Y-27632. | European journal of pharmacology 20080331 |
| Differential effects of two ROCK inhibitors, Fasudil and Y-27632, on optic nerve regeneration in adult cats. | Brain research 20080327 |
| Proinsulin C-peptide constricts glomerular afferent arterioles in diabetic mice. A potential renoprotective mechanism. | American journal of physiology. Regulatory, integrative and comparative physiology 20080301 |
| Roles of Rho guanosine 5'-triphosphatase A, Rho kinases, and extracellular signal regulated kinase (1/2) in prostaglandin E2-mediated migration of first-trimester human extravillous trophoblast. | Endocrinology 20080301 |
| Rho-kinase-dependent F-actin rearrangement is involved in the inhibition of PI3-kinase/Akt during ischemia-reperfusion-induced endothelial cell apoptosis. | Apoptosis : an international journal on programmed cell death 20080301 |
| Selectivity of ROCK inhibitors in the spontaneously tonic smooth muscle. | American journal of physiology. Gastrointestinal and liver physiology 20080301 |
| Rho kinase inhibition: a new approach for treating diabetic nephropathy? | Diabetes 20080301 |
| Purkinje cell survival in organotypic cultures: implication of Rho and its downstream effector ROCK. | Journal of neuroscience research 20080215 |
| Aggrecan components differentially modulate nerve growth factor-responsive and neurotrophin-3-responsive dorsal root ganglion neurite growth. | Journal of neuroscience research 20080215 |
| In vivo phosphorylation of regulatory light chain of myosin II in sea urchin eggs and its role in controlling myosin localization and function during cytokinesis. | Cell motility and the cytoskeleton 20080201 |
| Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide. | American journal of physiology. Lung cellular and molecular physiology 20080201 |
| The small GTPase Rac-1 is a regulator of mesangial cell morphology and thrombospondin-1 expression. | American journal of physiology. Renal physiology 20080201 |
| The mechanism of increasing outflow facility by rho-kinase inhibition with Y-27632 in bovine eyes. | Experimental eye research 20080201 |
| Nitric oxide does not downregulate Rho-kinase (ROCK-2) expression in rat coronary endothelial cells. | Journal of cardiovascular pharmacology 20080201 |
| Y-27632, a Rho-associated protein kinase inhibitor, attenuates neuronal cell death after transient retinal ischemia. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20080101 |
| Changes in the smooth muscle of the corpora cavernosum related to reversal of partial bladder outlet obstruction in rabbits. | Journal of andrology 20080101 |
| Heterogeneity in 5-HT-induced contractile and proliferative responses in rat pulmonary arterial bed. | Journal of vascular research 20080101 |
| ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells. | Brain : a journal of neurology 20080101 |
| Thromboxane A2 receptors in prostate carcinoma: expression and its role in regulating cell motility via small GTPase Rho. | Cancer research 20080101 |
| Analysis of the pattern of subcellular force generation by corneal fibroblasts after Rho activation. | Eye & contact lens 20080101 |
| Analysis of Rho-GTPase mimicry by a family of bacterial type III effector proteins. | Methods in enzymology 20080101 |
| Function of Rho-kinase in prostaglandin D2-induced interleukin-6 synthesis in osteoblasts. | Prostaglandins, leukotrienes, and essential fatty acids 20080101 |
| Simvastatin suppresses the differentiation of C2C12 myoblast cells via a Rac pathway. | Journal of muscle research and cell motility 20080101 |
| A negative modulatory role for rho and rho-associated kinase signaling in delamination of neural crest cells. | Neural development 20080101 |
| Abelson tyrosine kinase links PDGFbeta receptor activation to cytoskeletal regulation of NMDA receptors in CA1 hippocampal neurons. | Molecular brain 20080101 |
| [The contribution of protein kinase C and Rho-kinase to the control of the receptor-dependent artery contraction decreases with age independently of sympathetic innervation]. | Biofizika 20080101 |
| A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. | Proceedings of the National Academy of Sciences of the United States of America 20071218 |
| Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation. | Journal of cardiovascular pharmacology 20071201 |
| Contraction of tubulointerstitial fibrosis tissue in diabetic nephropathy, as demonstrated in an in vitro fibrosis model. | Virchows Archiv : an international journal of pathology 20071101 |
| Rho/Rho kinase is a key enzyme system involved in the angiotensin II signaling pathway of liver fibrosis and steatosis. | Journal of gastroenterology and hepatology 20071101 |
| Attenuation of actinomyosinII contractile activity in growth cones accelerates filopodia-guided and microtubule-based neurite elongation. | Brain research 20071024 |
| Volatile anesthetics affect the morphology of rat glioma C6 cells via RhoA, ERK, and Akt activation. | Journal of cellular biochemistry 20071001 |
| Intracellular signalling pathways in the vasoconstrictor response of mouse afferent arterioles to adenosine. | Acta physiologica (Oxford, England) 20071001 |
| Inhibition of Rho kinase (ROCK) increases neurite outgrowth on chondroitin sulphate proteoglycan in vitro and axonal regeneration in the adult optic nerve in vivo. | Journal of neurochemistry 20071001 |
| Rho guanosine 5'-triphosphatases differentially regulate insulin-like growth factor I (IGF-I) receptor-dependent and -independent actions of IGF-II on human trophoblast migration. | Endocrinology 20071001 |
| Characterization of protein kinase pathways responsible for Ca2+ sensitization in rat ileal longitudinal smooth muscle. | American journal of physiology. Gastrointestinal and liver physiology 20071001 |
| Sphingosine 1-phosphate rapidly increases endothelial barrier function independently of VE-cadherin but requires cell spreading and Rho kinase. | American journal of physiology. Cell physiology 20071001 |
| RhoA required for acid-induced stress fiber formation and trafficking and activation of NHE3. | American journal of physiology. Renal physiology 20071001 |
| Optimizing nitric oxide production by time dependent L-arginine administration in isolated human corpus cavernosum. | The Journal of urology 20071001 |
| Microtubule regulation of corneal fibroblast morphology and mechanical activity in 3-D culture. | Experimental eye research 20071001 |
| [Advances in the study of Rho kinase and its inhibitors]. | Yao xue xue bao = Acta pharmaceutica Sinica 20071001 |
| Role of alpha2C-adrenoceptors in the reduction of skin blood flow induced by local cooling in mice. | British journal of pharmacology 20070901 |
| VIP induces the elongation of dendrites and axons in cultured hippocampal neurons: role of microtubules. | Peptides 20070901 |
| Simvastatin enhances induction of inducible nitric oxide synthase in 3T3-L1 adipocytes. | Free radical research 20070901 |
| Comparative pharmacological analysis of Rho-kinase inhibitors and identification of molecular components of Ca2+ sensitization in the rat lower urinary tract. | Biochemical pharmacology 20070815 |
| Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C. | American journal of physiology. Lung cellular and molecular physiology 20070801 |
| Dynamics of actin filaments during tension-dependent formation of actin bundles. | Biochimica et biophysica acta 20070801 |
| Rho inhibition induces migration of mesenchymal stromal cells. | Stem cells (Dayton, Ohio) 20070801 |
| The rho-kinase inhibitors Y-27632 and fasudil act synergistically with imatinib to inhibit the expansion of ex vivo CD34(+) CML progenitor cells. | Leukemia 20070801 |
| Pericyte Rho GTPase mediates both pericyte contractile phenotype and capillary endothelial growth state. | The American journal of pathology 20070801 |
| Simvastatin inhibits TNFalpha-induced invasion of human cardiac myofibroblasts via both MMP-9-dependent and -independent mechanisms. | Journal of molecular and cellular cardiology 20070801 |
| Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats. | Journal of hypertension 20070801 |
| Small-molecule therapies for cardiac hypertrophy: moving beneath the cell surface. | Nature reviews. Drug discovery 20070801 |
| Effects of Rho-kinase and Src protein tyrosine kinase inhibition on agonist-induced vasoconstriction of arteries and veins of the equine laminar dermis. | American journal of veterinary research 20070801 |
| A minor role for Ca2+ sensitization in sustained contraction through activation of muscarinic receptor in circular muscle of rat distal colon. | Pflugers Archiv : European journal of physiology 20070701 |
| Acute inhibition of Rho-kinase improves cardiac contractile function in streptozotocin-diabetic rats. | Cardiovascular research 20070701 |
| Insulin increases the expression of contractile phenotypic markers in airway smooth muscle. | American journal of physiology. Cell physiology 20070701 |
| Crosstalk between HIF-1 and ROCK pathways in neuronal differentiation of mesenchymal stem cells, neurospheres and in PC12 neurite outgrowth. | Molecular and cellular neurosciences 20070701 |
| Differential effects of phenylalanine on Rac1, Cdc42, and RhoA expression and activity in cultured cortical neurons. | Pediatric research 20070701 |
| Role of the small GTPase RhoA in the hypoxia-induced decrease of plasma membrane Na,K-ATPase in A549 cells. | Journal of cell science 20070701 |
| Vasorelaxing effect of the Rho-kinase inhibitor, Y-27632, in isolated canine basilar arteries. | Neurological research 20070701 |
| Pravastatin induces thrombomodulin expression in TNFalpha-treated human aortic endothelial cells by inhibiting Rac1 and Cdc42 translocation and activity. | Journal of cellular biochemistry 20070601 |
| Rho kinase activation plays a major role as a mediator of irreversible injury in reperfused myocardium. | American journal of physiology. Heart and circulatory physiology 20070601 |
| The RISK of ROCK. | American journal of physiology. Heart and circulatory physiology 20070601 |
| Asbestos induces nitric oxide synthesis in mesothelioma cells via Rho signaling inhibition. | American journal of respiratory cell and molecular biology 20070601 |
| Sphingosine-1-phosphate receptor expression in cardiac fibroblasts is modulated by in vitro culture conditions. | American journal of physiology. Heart and circulatory physiology 20070601 |
| Protein kinase A inhibits lysophosphatidic acid-induced migration of airway smooth muscle cells. | The Journal of pharmacology and experimental therapeutics 20070601 |
| Cellular regulation of basal tone in internal anal sphincter smooth muscle by RhoA/ROCK. | American journal of physiology. Gastrointestinal and liver physiology 20070601 |
| Extracellular ATP induces assembly and activation of the myosin light chain phosphatase complex in endothelial cells. | Cardiovascular research 20070601 |
| Roles of P2X receptors and Ca2+ sensitization in extracellular adenosine triphosphate-induced hyperresponsiveness in airway smooth muscle. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20070601 |
| Somatostatin induces rapid contraction of neuroendocrine cells. | FEBS letters 20070515 |
| Heat shock augments myosin phosphatase target-subunit phosphorylation. | Biochemical and biophysical research communications 20070511 |
| Hypertonicity triggers RhoA-dependent assembly of myosin-containing striated polygonal actin networks in endothelial cells. | American journal of physiology. Cell physiology 20070501 |
| Increased arginase activity and endothelial dysfunction in human inflammatory bowel disease. | American journal of physiology. Gastrointestinal and liver physiology 20070501 |
| Rho-family small GTPases are involved in forskolin-induced cell-cell contact formation of renal glomerular podocytes in vitro. | Cell and tissue research 20070501 |
| Cytoskeleton/stretch-activated ion channel interaction regulates myogenic differentiation of skeletal myoblasts. | Journal of cellular physiology 20070501 |
| A novel ROCK inhibitor, Y-39983, promotes regeneration of crushed axons of retinal ganglion cells into the optic nerve of adult cats. | Experimental neurology 20070501 |
| The P2Y2 nucleotide receptor requires interaction with alpha v integrins to access and activate G12. | Journal of cell science 20070501 |
| Influence of actin cytoskeletal integrity on matrix metalloproteinase-2 activation in cultured human trabecular meshwork cells. | Investigative ophthalmology & visual science 20070501 |
| Testosterone regulates RhoA/Rho-kinase signaling in two distinct animal models of chemical diabetes. | The journal of sexual medicine 20070501 |
| Small GTPase Rho signaling is involved in beta1 integrin-mediated up-regulation of intercellular adhesion molecule 1 and receptor activator of nuclear factor kappaB ligand on osteoblasts and osteoclast maturation. | Biochemical and biophysical research communications 20070427 |
| Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction. | Circulation 20070403 |
| Oxytocin-induced phasic and tonic contractions are modulated by the contractile machinery rather than the quantity of oxytocin receptor. | American journal of physiology. Endocrinology and metabolism 20070401 |
| Collagen gel contractility is enhanced in human endometriotic stromal cells: a possible mechanism underlying the pathogenesis of endometriosis-associated fibrosis. | Human reproduction (Oxford, England) 20070401 |
| Hypotonicity causes actin reorganization and recruitment of the actin-binding ERM protein moesin in membrane protrusions in collecting duct principal cells. | American journal of physiology. Cell physiology 20070401 |
| RhoA/Rho kinase up-regulate Bax to activate a mitochondrial death pathway and induce cardiomyocyte apoptosis. | The Journal of biological chemistry 20070316 |
| Role of Rho kinases in PKG-mediated relaxation of pulmonary arteries of fetal lambs exposed to chronic high altitude hypoxia. | American journal of physiology. Lung cellular and molecular physiology 20070301 |
| Organized migration of epithelial cells requires control of adhesion and protrusion through Rho kinase effectors. | American journal of physiology. Gastrointestinal and liver physiology 20070301 |
| Inhibition of RhoA/Rho-kinase pathway suppresses the expression of type I collagen induced by TGF-beta2 in human retinal pigment epithelial cells. | Experimental eye research 20070301 |
| Involvement of nuclear factor-kB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells. | Molecular human reproduction 20070301 |
| Reduced contractile response to alpha1-adrenergic stimulation in atria from mice with chronic cardiac calmodulin kinase II inhibition. | Journal of molecular and cellular cardiology 20070301 |
| Direct effects of hydrogen peroxide on airway smooth muscle tone: roles of Ca2+ influx and Rho-kinase. | European journal of pharmacology 20070205 |
| Both Ca2+ -dependent and -independent pathways are involved in rat hepatic stellate cell contraction and intrahepatic hyperresponsiveness to methoxamine. | American journal of physiology. Gastrointestinal and liver physiology 20070201 |
| Involvement of microtubules, p38, and Rho kinases pathway in 2-methoxyestradiol-induced lung vascular barrier dysfunction. | American journal of physiology. Lung cellular and molecular physiology 20070201 |
| Pressor response induced by central angiotensin II is mediated by activation of Rho/Rho-kinase pathway via AT1 receptors. | Journal of hypertension 20070201 |
| Rho-associated kinase inhibitor reduces tumor recurrence after liver transplantation in a rat hepatoma model. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070201 |
| A role for WASP Interacting Protein, WIP, in fibroblast adhesion, spreading and migration. | The international journal of biochemistry & cell biology 20070101 |
| Cellular mechanisms of mainstream cigarette smoke-induced lung epithelial tight junction permeability changes in vitro. | Inhalation toxicology 20070101 |
| RhoA activation and interaction with Caveolin-1 are critical for pressure-induced myogenic tone in rat mesenteric resistance arteries. | Cardiovascular research 20070101 |
| RhoA/Rho kinase-mediated Ca2+ sensitization in the contraction of human prostate. | Neurourology and urodynamics 20070101 |
| Lysophosphatidic acid stimulation of platelets rapidly induces Ca2+-dependent dephosphorylation of cofilin that is independent of dense granule secretion and aggregation. | Blood cells, molecules & diseases 20070101 |
| Quantifying myosin light chain phosphorylation in single adherent cells with automated fluorescence microscopy. | BMC cell biology 20070101 |
| Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle. | European journal of pharmacology 20061215 |
| Isoprostane-induced airway hyperresponsiveness is dependent on internal Ca2+ handling and Rho/ROCK signaling. | American journal of physiology. Lung cellular and molecular physiology 20061201 |
| Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin. | American journal of respiratory cell and molecular biology 20061201 |
| Non-muscle myosin-II-B filament regulation of paracellular resistance in cervical epithelial cells is associated with modulation of the cortical acto-myosin. | Journal of the Society for Gynecologic Investigation 20061201 |
| Terbinafine inhibits endothelial cell migration through suppression of the Rho-mediated pathway. | Molecular cancer therapeutics 20061201 |
| A Rho-kinase inhibitor, Y-27632, reduces cholinergic contraction but not neurotransmitter release. | European journal of pharmacology 20061121 |
| Rapid stimulation of tyrosine phosphorylation signals downstream of G-protein-coupled receptors for thromboxane A2 in human platelets. | The Biochemical journal 20061115 |
| Rho kinase activation maintains high pulmonary vascular resistance in the ovine fetal lung. | American journal of physiology. Lung cellular and molecular physiology 20061101 |
| Cooperation of matrix metalloproteinases with the RhoA/Rho kinase and mitogen-activated protein kinase kinase-1/extracellular signal-regulated kinase signaling pathways is required for the sphingosine-1-phosphate-induced mobilization of marrow-derived stromal cells. | Stem cells (Dayton, Ohio) 20061101 |
| Hyaluronan induces vascular smooth muscle cell migration through RHAMM-mediated PI3K-dependent Rac activation. | Cardiovascular research 20061101 |
| Rho-kinase-mediated regulation of receptor-agonist-stimulated smooth muscle contraction. | Pflugers Archiv : European journal of physiology 20061101 |
| Quantitative assessment of local collagen matrix remodeling in 3-D culture: the role of Rho kinase. | Experimental cell research 20061101 |
| Changes of Rho kinase activity after hemorrhagic shock and its role in shock-induced biphasic response of vascular reactivity and calcium sensitivity. | Shock (Augusta, Ga.) 20061101 |
| Rho kinase regulates phagocytosis, surface expression of GlcNAc, and Golgi fragmentation of apoptotic PC12 cells. | Experimental cell research 20061015 |
| Myosin-based contraction is not necessary for cardiac c-looping in the chick embryo. | Anatomy and embryology 20061001 |
| Cholesterol modulates the volume-regulated anion current in Ehrlich-Lettre ascites cells via effects on Rho and F-actin. | American journal of physiology. Cell physiology 20061001 |
| Gabapentin-lactam induces dendritic filopodia and motility in cultured hippocampal neurons. | The Journal of pharmacology and experimental therapeutics 20061001 |
| Internal mammary artery smooth muscle cells resist migration and possess high antioxidant capacity. | Cardiovascular research 20061001 |
| Essential role of Rho/ROCK-dependent processes and actin dynamics in mediating leptin-induced hypertrophy in rat neonatal ventricular myocytes. | Cardiovascular research 20061001 |
| Ovariectomy augments hypertension through rho-kinase activation in the brain stem in female spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20061001 |
| Role of megakaryoblastic acute leukemia-1 in ERK1/2-dependent stimulation of serum response factor-driven transcription by BDNF or increased synaptic activity. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060927 |
| Mechanical stretch has contrasting effects on mediator release from bronchial epithelial cells, with a rho-kinase-dependent component to the mechanotransduction pathway. | Respiratory medicine 20060901 |
| Intracellular signal transduction for migration and actin remodeling in vascular smooth muscle cells after sphingosylphosphorylcholine stimulation. | American journal of physiology. Heart and circulatory physiology 20060901 |
| HMG-CoA reductase inhibitor fluvastatin prevents angiotensin II-induced cardiac hypertrophy via Rho kinase and inhibition of cyclin D1. | Life sciences 20060829 |
| Thrombin-induced contraction in alveolar epithelial cells probed by traction microscopy. | Journal of applied physiology (Bethesda, Md. : 1985) 20060801 |
| Chronic fluvastatin treatment alters vascular contraction by inhibiting the Rho/Rho-kinase pathway. | Clinical and experimental pharmacology & physiology 20060801 |
| Rho-kinase inhibitor, Y-27632, has an antinociceptive effect in mice. | European journal of pharmacology 20060710 |
| Statins revert doxorubicin resistance via nitric oxide in malignant mesothelioma. | International journal of cancer 20060701 |
| Increased RhoA/Rho-kinase signaling mediates spontaneous tone in aorta from angiotensin II-induced hypertensive rats. | The Journal of pharmacology and experimental therapeutics 20060701 |
| Imaging macrophage chemotaxis in vivo: studies of microtubule function in zebrafish wound inflammation. | Cell motility and the cytoskeleton 20060701 |
| Contribution of Rho-kinase in human gallbladder contractions. | European journal of pharmacology 20060701 |
| Reduction of tissue plasminogen activator-induced matrix metalloproteinase-9 by simvastatin in astrocytes. | Stroke 20060701 |
| Synergistic effects of CoCl(2) and ROCK inhibition on mesenchymal stem cell differentiation into neuron-like cells. | Journal of cell science 20060701 |
| The role of the RhoA/Rho-kinase signaling pathway in renal vascular reactivity in endothelial nitric oxide synthase null mice. | Journal of hypertension 20060701 |
| An MLCK-dependent window in late G1 controls S phase entry of proliferating rodent hepatocytes via ERK-p70S6K pathway. | Hepatology (Baltimore, Md.) 20060701 |
| Rho A/Rho kinase: human umbilical artery mRNA expression in normal and pre eclamptic pregnancies and functional role in isoprostane-induced vasoconstriction. | Reproduction (Cambridge, England) 20060701 |
| Rho-kinase contributes to hypoxia/reoxygenation-induced cerebral endothelial dysfunction. | Journal of cardiovascular pharmacology 20060701 |
| Phosphoryl transfer is not rate-limiting for the ROCK I-catalyzed kinase reaction. | Biochemistry 20060627 |
| Effect of doxazosin with and without rho-kinase inhibitor on human corpus cavernosum smooth muscle in the presence of bladder outlet obstruction. | The Journal of urology 20060601 |
| Myosin light chain kinase plays a role in the regulation of epithelial cell survival. | Journal of cell science 20060601 |
| Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation. | Experimental cell research 20060515 |
| Protective effect of fasudil, a Rho-kinase inhibitor, on chemokine expression, leukocyte recruitment, and hepatocellular apoptosis in septic liver injury. | Journal of leukocyte biology 20060501 |
| A role for Rho kinase in vascular contraction evoked by sodium fluoride. | Biochemical and biophysical research communications 20060428 |
| Involvement of Rho signaling in PAR2-mediated regulation of neutrophil adhesion to lung epithelial cells. | European journal of pharmacology 20060424 |
| Tubuloglomerular feedback-dependent modulation of renal myogenic autoregulation by nitric oxide. | American journal of physiology. Regulatory, integrative and comparative physiology 20060401 |
| Differential Rho-kinase dependency of full and partial muscarinic receptor agonists in airway smooth muscle contraction. | British journal of pharmacology 20060401 |
| Augmented sphingosylphosphorylcholine-induced Ca2+-sensitization of mesenteric artery contraction in spontaneously hypertensive rat. | Naunyn-Schmiedeberg's archives of pharmacology 20060401 |
| Sphingosine-1-phosphate modulates spiral modiolar artery tone: A potential role in vascular-based inner ear pathologies? | Cardiovascular research 20060401 |
| Attenuation of contractility in rat epididymal vas deferens by Rho kinase inhibitors. | Autonomic & autacoid pharmacology 20060401 |
| Lack of interaction between prostaglandin E2 receptor subtypes in regulating adenylyl cyclase activity in cultured rat dorsal root ganglion cells. | European journal of pharmacology 20060327 |
| Stretch-induced triphosphorylation of myosin light chain and myogenic tone in canine basilar artery. | European journal of pharmacology 20060318 |
| Role of Rho-kinase in guinea-pig gallbladder smooth muscle contraction. | European journal of pharmacology 20060318 |
| Rho-associated protein kinase inhibitor, Y-27632, induces alterations in adhesion, contraction and motility in cultured human trabecular meshwork cells. | Experimental eye research 20060301 |
| Increased basal phosphorylation of detrusor smooth muscle myosin in alloxan-induced diabetic rabbit is mediated by upregulation of Rho-kinase beta and CPI-17. | American journal of physiology. Renal physiology 20060301 |
| The role of Rho-associated kinase in differential regulation by statins of interleukin-1beta- and lipopolysaccharide-mediated nuclear factor kappaB activation and inducible nitric-oxide synthase gene expression in vascular smooth muscle cells. | Molecular pharmacology 20060301 |
| Pregnancy-induced modulation of calcium mobilization and down-regulation of Rho-kinase expression contribute to attenuated vasopressin-induced contraction of the rat aorta. | Vascular pharmacology 20060301 |
| Centaureidin promotes dendrite retraction of melanocytes by activating Rho. | Biochimica et biophysica acta 20060301 |
| Heat shock-induced augmentation of vascular contractility is independent of rho-kinase. | Clinical and experimental pharmacology & physiology 20060301 |
| Intrahepatic flow disturbance: possibility of a hidden cause of drug toxicity. | Journal of pharmacological sciences 20060301 |
| Defective RhoA/Rho-kinase signaling contributes to vascular hypocontractility and vasodilation in cirrhotic rats. | Gastroenterology 20060301 |
| Developmental regulation of nerve and receptor mediated contractions of mammalian urinary bladder smooth muscle. | European journal of pharmacology 20060217 |
| Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility. | Experimental cell research 20060215 |
| Inhibition of Rho-kinase normalizes nonspecific hyperresponsiveness in passively sensitized airway smooth muscle preparations. | European journal of pharmacology 20060215 |
| Involvement of rho kinase in the ouabain-induced contractions of the rat renal arteries. | Biochemical and biophysical research communications 20060210 |
| Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats. | American journal of physiology. Lung cellular and molecular physiology 20060201 |
| Involvement of ROCK-mediated endothelial tension development in neutrophil-stimulated microvascular leakage. | American journal of physiology. Heart and circulatory physiology 20060201 |
| Up-regulation of CPI-17 phosphorylation in diabetic vasculature and high glucose cultured vascular smooth muscle cells. | Cardiovascular research 20060201 |
| Rho/ROCK pathway as a target of tumor therapy. | Journal of neuroscience research 20060201 |
| Involvement of reduced sensitivity to Ca in beta-adrenergic action on airway smooth muscle. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060201 |
| The structure of dimeric ROCK I reveals the mechanism for ligand selectivity. | The Journal of biological chemistry 20060106 |
| Enhanced role for RhoA-associated kinase in adrenergic-mediated vasoconstriction in gracilis arteries from obese Zucker rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20060101 |
| Role of protein kinases in mediating diabetes-induced augmented vasoconstriction to endothelin-1 in the renal arteries of STZ-diabetic rats. | Cell biochemistry and function 20060101 |
| RhoA- and PKC-alpha-mediated phosphorylation of MYPT and its association with HSP27 in colonic smooth muscle cells. | American journal of physiology. Gastrointestinal and liver physiology 20060101 |
| Rho kinase regulates fragmentation and phagocytosis of apoptotic cells. | Experimental cell research 20060101 |
| Effects of calpain and Rho-kinase inhibitors on the acrosome reaction and motility of fowl spermatozoa in vitro. | Reproduction (Cambridge, England) 20060101 |
| Mechanism of increased alpha-adrenoceptor-mediated contraction in small resistance arteries of rats with heart failure. | Clinical and experimental pharmacology & physiology 20060101 |
| Expression, purification, and characterization of an enzymatically active truncated human rho-kinase I (ROCK I) domain expressed in Sf-9 insect cells. | Protein and peptide letters 20060101 |
| Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20060101 |
| Direct Rho-associated kinase inhibition [correction of inhibiton] induces cofilin dephosphorylation and neurite outgrowth in PC-12 cells. | Cellular & molecular biology letters 20060101 |
| Inhalation of the Rho-kinase inhibitor Y-27632 reverses allergen-induced airway hyperresponsiveness after the early and late asthmatic reaction. | Respiratory research 20060101 |
| Rho kinase expression and its central role in ovine gallbladder contractions elicited by a variety of excitatory stimuli. | European journal of pharmacology 20051228 |
| 5-Hydroxytryptamine as a potent migration enhancer of human aortic endothelial cells. | FEBS letters 20051219 |
| Lysophosphatidic acid induces histamine release from mast cells and skin fragments. | Pharmacology 20051201 |
| Role of Rho-kinase in reexpansion pulmonary edema in rabbits. | American journal of physiology. Lung cellular and molecular physiology 20051201 |
| Constrictor-induced translocation of NFAT3 in human and rat pulmonary artery smooth muscle. | American journal of physiology. Lung cellular and molecular physiology 20051201 |
| Role of Rho GTPase in astrocyte morphology and migratory response during in vitro wound healing. | Journal of neurochemistry 20051201 |
| Dose-dependent beneficial and detrimental effects of ROCK inhibitor Y27632 on axonal sprouting and functional recovery after rat spinal cord injury. | Experimental neurology 20051201 |
| [The role of specific ROCK inhibitor in the prevention of experimental PVR in rabbits]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20051201 |
| Relative contribution of Rho kinase and protein kinase C to myogenic tone in rat cerebral arteries in hypertension. | American journal of physiology. Heart and circulatory physiology 20051101 |
| Rho kinase inhibitors reduce neurally evoked contraction of the rat tail artery in vitro. | British journal of pharmacology 20051101 |
| Inhibition of the RhoA/Rho kinase system attenuates catecholamine biosynthesis in PC 12 rat pheochromocytoma cells. | Biochimica et biophysica acta 20051030 |
| Inhibition of iNOS gene expression by quercetin is mediated by the inhibition of IkappaB kinase, nuclear factor-kappa B and STAT1, and depends on heme oxygenase-1 induction in mouse BV-2 microglia. | European journal of pharmacology 20051003 |
| Sphingosylphosphorylcholine-induced vasoconstriction of pulmonary artery: activation of non-store-operated Ca2+ entry. | Cardiovascular research 20051001 |
| 5,6-EET-induced contraction of intralobar pulmonary arteries depends on the activation of Rho-kinase. | Journal of applied physiology (Bethesda, Md. : 1985) 20051001 |
| Proerectile effects of the Rho-kinase inhibitor (S)-(+)-2-methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine (H-1152) in the rat penis. | The Journal of pharmacology and experimental therapeutics 20051001 |
| Okadaic acid induces phosphorylation and translocation of myosin phosphatase target subunit 1 influencing myosin phosphorylation, stress fiber assembly and cell migration in HepG2 cells. | Cellular signalling 20051001 |
| Non-capacitative calcium entry--extension of the possibilities for calcium entry in vascular tissue. | Cardiovascular research 20051001 |
| Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection. | Stroke 20051001 |
| Expression and functional role of the RhoA/Rho-kinase pathway in rat coeliac artery. | Clinical and experimental pharmacology & physiology 20051001 |
| Cooling-induced contraction of the rat gastric fundus: mediation via transient receptor potential (TRP) cation channel TRPM8 receptor and Rho-kinase activation. | Clinical and experimental pharmacology & physiology 20051001 |
| Inhibition of Rho-kinase affects astrocytoma morphology, motility, and invasion through activation of Rac1. | Cancer research 20051001 |
| Redundant mechanisms for anaphase chromosome movements: crane-fly spermatocyte spindles normally use actin filaments but also can function without them. | Protoplasma 20051001 |
| A key role for Abl family kinases in EphA receptor-mediated growth cone collapse. | Molecular and cellular neurosciences 20050901 |
| Active relocation of chromatin and endoplasmic reticulum into blebs in late apoptotic cells. | Journal of cell science 20050901 |
| Multiple signaling pathways are activated during insulin-like growth factor-I (IGF-I) stimulated breast cancer cell migration. | Breast cancer research and treatment 20050901 |
| PHI-1 induced enhancement of myosin phosphorylation in chicken smooth muscle. | FEBS letters 20050815 |
| RhoA-Rho kinase pathway mediates thrombin- and U-46619-induced phosphorylation of a myosin phosphatase inhibitor, CPI-17, in vascular smooth muscle cells. | American journal of physiology. Cell physiology 20050801 |
| Inhibition of rho-kinase in the nucleus tractus solitarius enhances glutamate sensitivity in rats. | Hypertension (Dallas, Tex. : 1979) 20050801 |
| Intrathecal administration of Y-27632, a specific rho-associated kinase inhibitor, for rat neoplastic meningitis. | Molecular cancer research : MCR 20050801 |
| Cdc42 contributes to phorbol ester-induced Ca2+-independent contraction of pulmonary artery smooth muscle. | The Journal of veterinary medical science 20050801 |
| Endothelin-1-induced translocation of RhoA is mediated by endothelin ET(A) receptors in rat bronchial smooth muscle. | European journal of pharmacology 20050711 |
| ROK-induced cross-link formation stiffens passive muscle: reversible strain-induced stress softening in rabbit detrusor. | American journal of physiology. Cell physiology 20050701 |
| Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1. | The Journal of biological chemistry 20050701 |
| Regulation of vascular tone from spontaneously hypertensive rats by the HMG-CoA reductase inhibitor, simvastatin. | Pharmacology 20050701 |
| Thrombin modulates the expression of a set of genes including thrombospondin-1 in human microvascular endothelial cells. | The Journal of biological chemistry 20050610 |
| Attenuation of endotoxin-induced acute lung injury by the Rho-associated kinase inhibitor, Y-27632. | American journal of respiratory cell and molecular biology 20050601 |
| Effects of ML-7 and Y-27632 on carbachol- and endothelin-1-induced contraction of bovine trabecular meshwork. | Experimental eye research 20050601 |
| Trapidil inhibits platelet-derived growth factor-induced migration via protein kinase A and RhoA/Rho-associated kinase in rat vascular smooth muscle cells. | European journal of pharmacology 20050516 |
| Mitogen-activated protein kinase contributes to elevated basal tone in aortic smooth muscle from hypertensive rats. | European journal of pharmacology 20050509 |
| Contractile properties of the cultured vascular smooth muscle cells: the crucial role played by RhoA in the regulation of contractility. | Circulation research 20050429 |
| Activation of protease-activated receptor-1 triggers astrogliosis after brain injury. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427 |
| Statins potentiate the IFN-gamma-induced upregulation of group IIA phospholipase A2 in human aortic smooth muscle cells and HepG2 hepatoma cells. | Biochimica et biophysica acta 20050415 |
| Postnatal maturational shift from PKCzeta and voltage-gated K+ channels to RhoA/Rho kinase in pulmonary vasoconstriction. | Cardiovascular research 20050401 |
| Rho-kinase (ROCK-1 and ROCK-2) upregulation in oleic acid-induced lung injury and its restoration by Y-27632. | European journal of pharmacology 20050307 |
| Inhaled Rho kinase inhibitors are potent and selective vasodilators in rat pulmonary hypertension. | American journal of respiratory and critical care medicine 20050301 |
| Small guanine nucleotide-binding protein Rho and myocardial function. | Acta pharmacologica Sinica 20050301 |
| Tocolytic effect of a Rho-kinase inhibitor in a mouse model of lipopolysaccharide-induced preterm delivery. | American journal of obstetrics and gynecology 20050301 |
| Myosin light chain kinase and Rho-kinase participate in P2Y receptor-mediated acceleration of permeability through the endothelial cell layer. | The Journal of pharmacy and pharmacology 20050301 |
| Differential inhibition by the Rho kinase inhibitor Y-27632 of the increases in contractility and Ca2+ transients induced by endothelin-1 in rabbit ventricular myocytes. | Naunyn-Schmiedeberg's archives of pharmacology 20050301 |
| Age-dependent enhancement of hippocampal long-term potentiation and impairment of spatial learning through the Rho-associated kinase pathway in protein tyrosine phosphatase receptor type Z-deficient mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050202 |
| RhoA and Rho-kinase dependent and independent signals mediate TGF-beta-induced pulmonary endothelial cytoskeletal reorganization and permeability. | American journal of physiology. Lung cellular and molecular physiology 20050201 |
| Two G protein-coupled receptors activate Na+/H+ exchanger isoform 1 in Chinese hamster lung fibroblasts through an ERK-dependent pathway. | Cellular signalling 20050201 |
| Impaired endothelium-dependent responses and enhanced influence of Rho-kinase in cerebral arterioles in type II diabetes. | Stroke 20050201 |
| Effects of the Rho kinase inhibitor Y-27632 and the phosphatase inhibitor calyculin A on outflow facility in monkeys. | Experimental eye research 20050201 |
| Rho-kinase and myosin II activities are required for cell type and environment specific migration. | Genes to cells : devoted to molecular & cellular mechanisms 20050201 |
| Extracellular signal-regulated kinase1/2 in contraction of vascular smooth muscle. | Life sciences 20050107 |
| Effects of Y-27632, a selective Rho-kinase inhibitor, on myocardial preconditioning in anesthetized rats. | Biochemical pharmacology 20050101 |
| Interactive role of protein kinase C-delta with rho-kinase in the development of cerebral vasospasm in a canine two-hemorrhage model. | Journal of vascular research 20050101 |
| Cardioprotective mechanisms of Rho-kinase inhibition associated with eNOS and oxidative stress-LOX-1 pathway in Dahl salt-sensitive hypertensive rats. | Journal of hypertension 20050101 |
| Attenuated noradrenaline-induced contraction of pulmonary arteries from rats treated with monocrotaline: role of rho kinase. | Journal of vascular research 20050101 |
| The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner. | The Journal of biological chemistry 20041224 |
| RhoA and Rac1 are both required for efficient wound closure of airway epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20041201 |
| Vasoconstrictor mechanisms in the cerebral circulation are unaffected by insulin resistance. | American journal of physiology. Regulatory, integrative and comparative physiology 20041201 |
| Rho-kinase inhibition enhances axonal plasticity and attenuates cold hyperalgesia after dorsal rhizotomy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201 |
| N-cadherin juxtamembrane domain modulates voltage-gated Ca2+ current via RhoA GTPase and Rho-associated kinase. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041201 |
| Inactivation of Rho/ROCK signaling is crucial for the nuclear accumulation of FKHR and myoblast fusion. | The Journal of biological chemistry 20041105 |
| The role of Rho kinase and extracellular regulated kinase-mitogen-activated protein kinase in alpha2-adrenoceptor-mediated vasoconstriction in the porcine palmar lateral vein. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Differential regulation of human lung epithelial and endothelial barrier function by thrombin. | American journal of respiratory cell and molecular biology 20041101 |
| HMG-CoA reductase inhibitors up-regulate anti-aging klotho mRNA via RhoA inactivation in IMCD3 cells. | Cardiovascular research 20041101 |
| The permeability-reducing effects of prostacyclin and inhibition of Rho kinase do not counteract endotoxin-induced increase in permeability in cat skeletal muscle. | Microvascular research 20041101 |
| Differential interplay between protein kinase C and Rho-kinase in the endothelin-1-induced and pressure-induced contractions of rat posterior cerebral artery. | Journal of cardiovascular pharmacology 20041101 |
| Cell type-specific regulation of RhoA activity during cytokinesis. | The Journal of biological chemistry 20041022 |
| Rho/ROCK and Cdk5 effects on phosphorylation of a beta-thymosin repeat protein in Hermissenda. | Biochemical and biophysical research communications 20041015 |
| Sphingosine 1-phosphate stimulates smooth muscle cell differentiation and proliferation by activating separate serum response factor co-factors. | The Journal of biological chemistry 20041008 |
| Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats. | American journal of physiology. Lung cellular and molecular physiology 20041001 |
| Effect of changes in pH on wall tension in isolated rat pulmonary artery: role of the RhoA/Rho-kinase pathway. | American journal of physiology. Lung cellular and molecular physiology 20041001 |
| KCl evokes contraction of airway smooth muscle via activation of RhoA and Rho-kinase. | American journal of physiology. Lung cellular and molecular physiology 20041001 |
| Microtubule disassembly induces cytoskeletal remodeling and lung vascular barrier dysfunction: role of Rho-dependent mechanisms. | Journal of cellular physiology 20041001 |
| Expression of Rho-kinase (ROCK-1 and ROCK-2) and its substantial role in the contractile activity of the sheep ureter. | British journal of pharmacology 20041001 |
| Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta. | American journal of physiology. Heart and circulatory physiology 20041001 |
| [Role of ROK in contraction of rat femoral arteries after 14 d tail suspension]. | Hang tian yi xue yu yi xue gong cheng = Space medicine & medical engineering 20041001 |
| Abl tyrosine kinase promotes dendrogenesis by inducing actin cytoskeletal rearrangements in cooperation with Rho family small GTPases in hippocampal neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040929 |
| A role for hippocampal Rho-ROCK pathway in long-term spatial memory. | Biochemical and biophysical research communications 20040924 |
| Rho kinase-induced nuclear translocation of ERK1/ERK2 in smooth muscle cell mitogenesis caused by serotonin. | Circulation research 20040917 |
| Upregulation of Rho-kinase (ROCK-2) expression and enhanced contraction to endothelin-1 in the mesenteric artery from lipopolysaccharide-treated rats. | European journal of pharmacology 20040913 |
| Aggregation of integrins and RhoA activation are required for Thy-1-induced morphological changes in astrocytes. | The Journal of biological chemistry 20040910 |
| Regulation of vascular endothelial growth factor receptor 2-mediated phosphorylation of focal adhesion kinase by heat shock protein 90 and Src kinase activities. | The Journal of biological chemistry 20040910 |
| Evidence that estrogen suppresses rho-kinase function in the cerebral circulation in vivo. | Stroke 20040901 |
| Itch-scratch responses induced by lysophosphatidic acid in mice. | Pharmacology 20040901 |
| Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart. | Cardiovascular research 20040901 |
| Mechanisms of neurokinin A- and substance P-induced contractions in rat detrusor smooth muscle in vitro. | BJU international 20040901 |
| The small GTPase Rac is involved in clustering of hippocampal neurons and fasciculation of their neurites. | Naunyn-Schmiedeberg's archives of pharmacology 20040901 |
| Stretch of the vascular wall induces smooth muscle differentiation by promoting actin polymerization. | The Journal of biological chemistry 20040813 |
| Role of adhesion and contraction in Rac 1-regulated endothelial barrier function in vivo and in vitro. | American journal of physiology. Heart and circulatory physiology 20040801 |
| Unique morphology and focal adhesion development of valvular endothelial cells in static and fluid flow environments. | Arteriosclerosis, thrombosis, and vascular biology 20040801 |
| Chronic mevastatin modulates receptor-dependent vascular contraction in eNOS-deficient mice. | American journal of physiology. Regulatory, integrative and comparative physiology 20040801 |
| Ca2+ sensitization in contraction of human bladder smooth muscle. | The Journal of urology 20040801 |
| Actions downstream of cyclic GMP/protein kinase G can reverse protein kinase C-mediated phosphorylation of CPI-17 and Ca²⁺ sensitization in smooth muscle. | The Journal of biological chemistry 20040709 |
| Pressor responses to platelet-activating factor and thromboxane are mediated by Rho-kinase. | American journal of physiology. Lung cellular and molecular physiology 20040701 |
| An essential role of Cav1.2 L-type calcium channel for urinary bladder function. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040701 |
| P-cresol, a uremic retention solute, alters the endothelial barrier function in vitro. | Thrombosis and haemostasis 20040701 |
| Controlled pseudopod extension of human neutrophils stimulated with different chemoattractants. | Biophysical journal 20040701 |
| CD44 interaction with Na+-H+ exchanger (NHE1) creates acidic microenvironments leading to hyaluronidase-2 and cathepsin B activation and breast tumor cell invasion. | The Journal of biological chemistry 20040625 |
| Partial protective effect of Y-27632, a Rho kinase inhibitor, against hepatic ischemia-reperfusion injury in rats. | European journal of pharmacology 20040616 |
| Atorvastatin completely inhibits VEGF-induced ACE upregulation in human endothelial cells. | American journal of physiology. Heart and circulatory physiology 20040601 |
| Rho/Rho kinase and phosphoinositide 3-kinase are parallel pathways in the development of spontaneous arterial tone in deoxycorticosterone acetate-salt hypertension. | The Journal of pharmacology and experimental therapeutics 20040601 |
| The nucleotide receptor P2X7 mediates actin reorganization and membrane blebbing in RAW 264.7 macrophages via p38 MAP kinase and Rho. | Journal of leukocyte biology 20040601 |
| Mechanisms involved in carbachol-induced Ca(2+) sensitization of contractile elements in rat proximal and distal colon. | British journal of pharmacology 20040601 |
| Angiotensin II-induced vascular dysfunction is mediated by the AT1A receptor in mice. | Hypertension (Dallas, Tex. : 1979) 20040501 |
| Female pig urethral tone is dependent on Rho guanosine triphosphatases and Rho-associated kinase. | The Journal of urology 20040501 |
| Role of ERK and Rho kinase pathways in central pressor action of urotensin II. | Journal of hypertension 20040501 |
| GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions. | Circulation research 20040430 |
| Endothelial dysfunction and altered bradykinin response due to oxidative stress induced by serum deprivation in the bovine cerebral artery. | European journal of pharmacology 20040426 |
| Length control is determined by the pattern of cytoskeleton. | Journal of cell science 20040415 |
| Regulation of osteoblast differentiation by Pasteurella multocida toxin (PMT): a role for Rho GTPase in bone formation. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20040401 |
| Development of a microplate bioassay for monocyte chemoattractant protein-1 based on activation of p44/42 mitogen-activated protein kinase. | Analytical biochemistry 20040401 |
| The role of the cytoskeleton in cellular adhesion molecule expression in tumor necrosis factor-stimulated endothelial cells. | Journal of cellular biochemistry 20040401 |
| Phosphodiesterase-5 inhibition synergizes rho-kinase antagonism and enhances erectile response in male hypertensive rats. | International journal of impotence research 20040401 |
| Rho kinase inhibition initiates apoptosis in human airway epithelial cells. | American journal of respiratory cell and molecular biology 20040301 |
| Pyrimidine nucleotides suppress KDR currents and depolarize rat cerebral arteries by activating Rho kinase. | American journal of physiology. Heart and circulatory physiology 20040301 |
| Involvement of RhoA and Rho kinase in neutrophil-stimulated endothelial hyperpermeability. | American journal of physiology. Heart and circulatory physiology 20040301 |
| Characterization of G proteins involved in activation of nonselective cation channels and arachidonic acid release by norepinephrine/alpha1A-adrenergic receptors. | American journal of physiology. Cell physiology 20040301 |
| ROCK inhibitor (Y27632) increases apoptosis and disrupts the actin cortical mat in embryonic avian corneal epithelium. | Developmental dynamics : an official publication of the American Association of Anatomists 20040301 |
| [Involvement of small GTPase Rho and Rho-kinase in the pathogenesis of hypertension and hypertensive target organ damage]. | Nihon rinsho. Japanese journal of clinical medicine 20040301 |
| HSP27 regulates fibroblast adhesion, motility, and matrix contraction. | Cell stress & chaperones 20040301 |
| The apolipoprotein(a) component of lipoprotein(a) stimulates actin stress fiber formation and loss of cell-cell contact in cultured endothelial cells. | The Journal of biological chemistry 20040220 |
| A role of activated Sonic hedgehog signaling for the cellular proliferation of oral squamous cell carcinoma cell line. | Biochemical and biophysical research communications 20040206 |
| High glucose-induced upregulation of osteopontin is mediated via Rho/Rho kinase pathway in cultured rat aortic smooth muscle cells. | Arteriosclerosis, thrombosis, and vascular biology 20040201 |
| Myosin-mediated cytoskeleton contraction and Rho GTPases regulate laminin-5 matrix assembly. | Cell motility and the cytoskeleton 20040201 |
| Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition. | Hypertension (Dallas, Tex. : 1979) 20040201 |
| Involvement of rho-kinase pathway in contractile activity of rabbit RPE cells in vivo and in vitro. | Investigative ophthalmology & visual science 20040201 |
| [Rho-kinase inhibitor]. | Nihon rinsho. Japanese journal of clinical medicine 20040201 |
| Enhancement of migration and invasion of hepatoma cells via a Rho GTPase signaling pathway. | World journal of gastroenterology 20040115 |
| Rho GTPases and phosphoinositide 3-kinase organize formation of branched dendrites. | The Journal of biological chemistry 20040102 |
| Rho-kinase-mediated Ca2+-independent contraction in rat embryo fibroblasts. | American journal of physiology. Cell physiology 20040101 |
| Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder. | British journal of pharmacology 20040101 |
| Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway. | Experimental cell research 20040101 |
| The Rho-ROCK system as a new therapeutic target for preventing interstitial fibrosis. | Drug news & perspectives 20040101 |
| Rho-ROCK signal pathway regulates microtubule-based process formation of cultured podocytes--inhibition of ROCK promoted process elongation. | Nephron. Experimental nephrology 20040101 |
| Effects of HA-1077 and Y-27632, two rho-kinase inhibitors, in the human umbilical artery. | Cell biochemistry and biophysics 20040101 |
| Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. | Current biology : CB 20031216 |
| Engulfment of apoptotic cells is negatively regulated by Rho-mediated signaling. | The Journal of biological chemistry 20031212 |
| Rho kinase inhibitors block activation of pancreatic stellate cells. | British journal of pharmacology 20031201 |
| Y-27632, a Rho-kinase inhibitor, inhibits proliferation and adrenergic contraction of prostatic smooth muscle cells. | The Journal of urology 20031201 |
| Role of Rho kinase and actin filament in the increased vascular permeability of skin venules in rats after scalding. | Burns : journal of the International Society for Burn Injuries 20031201 |
| Edaravone, a radical scavenger, may enhance or produce antiproliferative effects of fluvastatin, amlodipine, ozagrel, GF109203X and Y27632 on cultured basilar artery smooth muscle cells. | Biological & pharmaceutical bulletin 20031201 |
| Protein kinase A in complex with Rho-kinase inhibitors Y-27632, Fasudil, and H-1152P: structural basis of selectivity. | Structure (London, England : 1993) 20031201 |
| The role of rho and rho-dependent kinase in serotonin-induced contraction observed in bovine middle cerebral artery. | The Tohoku journal of experimental medicine 20031201 |
| Nonsteroidal anti-inflammatory drugs can lower amyloidogenic Abeta42 by inhibiting Rho. | Science (New York, N.Y.) 20031114 |
| Modulation of the expression of connective tissue growth factor by alterations of the cytoskeleton. | The Journal of biological chemistry 20031107 |
| Involvement of Rho/Rho kinase pathway in regulation of apoptosis in rat hepatic stellate cells. | American journal of physiology. Gastrointestinal and liver physiology 20031101 |
| Rho inhibition decreases TNF-induced endothelial MAPK activation and monolayer permeability. | Journal of applied physiology (Bethesda, Md. : 1985) 20031101 |
| Rho-kinase inhibitor inhibits both myosin phosphorylation-dependent and -independent enhancement of myofilament Ca2+ sensitivity in the bovine middle cerebral artery. | British journal of pharmacology 20031101 |
| Comparison of effects of Y-27632 and Isoproterenol on release of cytokines from human peripheral T cells. | International immunopharmacology 20031101 |
| Lysophosphatidic acid induces process retraction in CG-4 line oligodendrocytes and oligodendrocyte precursor cells but not in differentiated oligodendrocytes. | Journal of neurochemistry 20031101 |
| Different migratory and proliferative properties of smooth muscle cells of coronary and femoral artery. | Atherosclerosis 20031101 |
| Rho-associated protein kinase contributes to early atherosclerotic lesion formation in mice. | Circulation research 20031031 |
| Enhancement of cisplatin-induced cytotoxicity by ROCK inhibitor through suppression of focal adhesion kinase-independent mechanism in lung carcinoma cells. | International journal of oncology 20031001 |
| Vasoconstrictor responses, and underlying mechanisms, to isoprostanes in human and porcine bronchial arterial smooth muscle. | British journal of pharmacology 20031001 |
| Expression of Rho-kinase and its functional role in the contractile activity of the mouse vas deferens. | British journal of pharmacology 20031001 |
| Novel agents for sexual dysfunction. | BJU international 20031001 |
| Force and myosin light chain phosphorylation in dog airway smooth muscle activated in different ways. | Respiratory physiology & neurobiology 20030916 |
| Rho-dependent kinase is involved in agonist-activated calcium entry in rat arteries. | The Journal of physiology 20030915 |
| ROCK-dependent and ROCK-independent control of cochlear outer hair cell electromotility. | The Journal of biological chemistry 20030912 |
| Caspase activation during phorbol ester-induced apoptosis requires ROCK-dependent myosin-mediated contraction. | Journal of cell science 20030901 |
| Sevoflurane inhibits guanosine 5'-[gamma-thio]triphosphate-stimulated, Rho/Rho-kinase-mediated contraction of isolated rat aortic smooth muscle. | Anesthesiology 20030901 |
| Therapeutic significance of Y-27632, a Rho-kinase inhibitor, on the established liver fibrosis. | The Journal of surgical research 20030901 |
| Receptor-independent activation of Rho-kinase-mediated calcium sensitisation in smooth muscle. | British journal of pharmacology 20030802 |
| Erectile physiological and pathophysiological pathways involved in erectile dysfunction. | The Journal of urology 20030801 |
| Effects of the Rho-kinase inhibitors, Y-27632 and fasudil, on the corpus cavernosum from diabetic mice. | European journal of pharmacology 20030711 |
| Implication of Rho-associated kinase in the elevation of extracellular dopamine levels and its related behaviors induced by methamphetamine in rats. | Journal of neurochemistry 20030701 |
| Rho/Rho-kinase pathway in brain stem contributes to blood pressure regulation via sympathetic nervous system: possible involvement in neural mechanisms of hypertension. | Circulation research 20030627 |
| CCR7 ligands induce rapid endocytosis in mature dendritic cells with concomitant up-regulation of Cdc42 and Rac activities. | Blood 20030615 |
| Astrocyte stellation induced by Rho kinase inhibitors in culture. | Brain research. Developmental brain research 20030612 |
| Improved erectile function after Rho-kinase inhibition in a rat castrate model of erectile dysfunction. | American journal of physiology. Regulatory, integrative and comparative physiology 20030601 |
| Sertoli-germ cell adherens junction dynamics in the testis are regulated by RhoB GTPase via the ROCK/LIMK signaling pathway. | Biology of reproduction 20030601 |
| Rho-Rho kinase pathway is involved in the regulation of myogenic tone and pump activity in isolated lymph vessels. | American journal of physiology. Heart and circulatory physiology 20030601 |
| Variations in cell signaling pathways for different vasoconstrictor agonists in renal circulation of the rat. | Kidney international 20030601 |
| P2X7 receptor-dependent blebbing and the activation of Rho-effector kinases, caspases, and IL-1 beta release. | Journal of immunology (Baltimore, Md. : 1950) 20030601 |
| Oxidized LDL and its compound lysophosphatidylcholine potentiate AngII-induced vasoconstriction by stimulation of RhoA. | Journal of the American Society of Nephrology : JASN 20030601 |
| Modulation of Ca2+ sensitivity regulates contractility of rabbit corpus cavernosum smooth muscle. | The Journal of urology 20030601 |
| Intracellular signal transduction modulating expression of plasminogen activator inhibitor-1 in adipocytes. | Biochemical pharmacology 20030601 |
| Deactivation of ROCK-II by Y-27632 enhances basolateral pancreatic enzyme secretion and acute pancreatitis induced by CCK analogues. | Biochemical and biophysical research communications 20030530 |
| Rho kinase blockade prevents inflammation via nuclear factor kappa B inhibition: evidence in Crohn's disease and experimental colitis. | Gastroenterology 20030501 |
| Angiopoietin-1 inhibits endothelial permeability, neutrophil adherence and IL-8 production. | British journal of pharmacology 20030501 |
| Inhibition of high K+-induced contraction by the ROCKs inhibitor Y-27632 in vascular smooth muscle: possible involvement of ROCKs in a signal transduction pathway. | Journal of pharmacological sciences 20030501 |
| Functional roles of the rho/rho kinase pathway and protein kinase C in the regulation of cerebrovascular constriction mediated by hemoglobin: relevance to subarachnoid hemorrhage and vasospasm. | Circulation research 20030418 |
| A novel endocytic pathway induced by clustering endothelial ICAM-1 or PECAM-1. | Journal of cell science 20030415 |
| RhoA and ROCK promote migration by limiting membrane protrusions. | The Journal of biological chemistry 20030411 |
| Involvement of Rho/Rho-kinase signalling in the contractile activity and acetylcholine release in the mouse gastric fundus. | Biochemical and biophysical research communications 20030411 |
| Rapid actin transport during cell protrusion. | Science (New York, N.Y.) 20030404 |
| Polyamines regulate Rho-kinase and myosin phosphorylation during intestinal epithelial restitution. | American journal of physiology. Cell physiology 20030401 |
| Sphingosine 1-phosphate induces contraction of coronary artery smooth muscle cells via S1P2. | Cardiovascular research 20030401 |
| Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells. | The Journal of physiology 20030315 |
| Prevention of ischemia-reperfusion-induced hepatic microcirculatory disruption by inhibiting stellate cell contraction using rock inhibitor. | Transplantation 20030315 |
| Activation of RhoA and inhibition of myosin phosphatase as important components in hypertension in vascular smooth muscle. | Circulation research 20030307 |
| Microtubule-disruption-induced and chemotactic-peptide-induced migration of human neutrophils: implications for differential sets of signalling pathways. | Journal of cell science 20030301 |
| The Rho/ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar. | Molecular and cellular neurosciences 20030301 |
| Rho kinase inhibition enhances axonal regeneration in the injured CNS. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030215 |
| Independent roles of Rho-GTPases in growth cone and axonal behavior. | Journal of neurobiology 20030205 |
| Inhibition of Rho-kinase reduces renal Na-H exchanger activity and causes natriuresis in rat. | The Journal of pharmacology and experimental therapeutics 20030201 |
| Rho kinase and matrix metalloproteinase inhibitors cooperate to inhibit angiogenesis and growth of human prostate cancer xenotransplants. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030201 |
| Phosphorylation of the myosin phosphatase targeting subunit and CPI-17 during Ca2+ sensitization in rabbit smooth muscle. | The Journal of physiology 20030201 |
| A novel inhibitor of Rho-associated protein kinase, Y-27632, ameliorates hepatic ischemia and reperfusion injury in rats. | Surgery 20030201 |
| Cardiovascular effects of Y-27632, a selective Rho-associated kinase inhibitor, assessed in the halothane-anesthetized canine model. | European journal of pharmacology 20030126 |
| A possible role of RhoA/Rho-kinase in experimental spinal cord injury in rat. | Brain research 20030103 |
| Rho-kinase inhibition blunts renal vasoconstriction induced by distinct signaling pathways in vivo. | Journal of the American Society of Nephrology : JASN 20030101 |
| The Rho-kinase inhibitor Y-27632 and the soluble guanylyl cyclase activator BAY41-2272 relax rabbit vaginal wall and clitoral corpus cavernosum. | British journal of pharmacology 20030101 |
| Inhibition of rho-associated kinase reduces MLC20 phosphorylation and contractility of intact myometrium and attenuates agonist-induced Ca2+ sensitization of force of permeabilized rat myometrium. | The Journal of veterinary medical science 20030101 |
| Comparison of inhibitory effects of Y-27632, a Rho kinase inhibitor, in strips of small and large mesenteric arteries from spontaneously hypertensive and normotensive Wistar-Kyoto rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20030101 |
| Lysophosphatidic acid enhances in vivo infiltration and activation of guinea pig eosinophils and neutrophils via a Rho/Rho-associated protein kinase-mediated pathway. | Journal of pharmacological sciences 20030101 |
| Rho and p38 MAP kinase signaling pathways mediate LPA-stimulated hepatic myofibroblast migration. | Journal of biomedical science 20030101 |
| Contribution of Rho A and Rho kinase to platelet-derived growth factor-BB-induced proliferation of vascular smooth muscle cells. | Journal of atherosclerosis and thrombosis 20030101 |
| Vessel- and vasoconstrictor-dependent role of rho/rho-kinase in renal microvascular tone. | Journal of vascular research 20030101 |
| RhoA kinase and protein kinase C participate in regulation of rabbit stomach fundus smooth muscle contraction. | British journal of pharmacology 20021201 |
| Small guanosine triphospatase RhoA and Rho-associated kinase as regulators of trophoblast migration. | The Journal of clinical endocrinology and metabolism 20021201 |
| Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related Peptide. | Stroke 20021201 |
| ROCK inhibitor Y-27632 prevents primary graft non-function caused by warm ischemia/reperfusion in rat liver transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20021201 |
| Role of rho-kinase activity in angiotensin II-induced contraction of rabbit clitoral cavernosum smooth muscle. | International journal of impotence research 20021201 |
| Beneficial effects of a Rho-associated coiled-coli forming protein serine/threonine kinase inhibitor, Y-27632, on survival of recipients in rat liver transplantation following warm ischemia. | Transplantation proceedings 20021101 |
| Cerivastatin, a hydroxymethylglutaryl coenzyme A reductase inhibitor, inhibits cardiac myocyte hypertrophy induced by endothelin. | European journal of pharmacology 20021025 |
| Conventional protein kinase C mediates phorbol-dibutyrate-induced cytoskeletal remodeling in a7r5 smooth muscle cells. | Experimental cell research 20021015 |
| Translocation of Na(+),K(+)-ATPase is induced by Rho small GTPase in renal epithelial cells. | Biochemical and biophysical research communications 20021011 |
| Acute and chronic NOS inhibition enhances alpha(2)- adrenoreceptor-stimulated RhoA and Rho kinase in rat aorta. | American journal of physiology. Heart and circulatory physiology 20021001 |
| Myosin light chain phosphorylation and growth cone motility. | Journal of neurobiology 20020905 |
| Mechanisms of NOS2 regulation by Rho GTPase signaling in airway epithelial cells. | American journal of physiology. Lung cellular and molecular physiology 20020901 |
| Requirement for RhoA kinase activation in leukocyte de-adhesion. | Journal of immunology (Baltimore, Md. : 1950) 20020901 |
| Independence of plasma membrane blebbing from other biochemical and biological characteristics of apoptotic cells. | Journal of biochemistry 20020901 |
| Role of Rho kinase signalling in healthy and varicose human saphenous veins. | British journal of pharmacology 20020901 |
| Occupation of the prostaglandin E2-type 1 receptor increases rat atrial contractility via a Y-27632-sensitive pathway. | Prostaglandins & other lipid mediators 20020901 |
| Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells. | Oncogene 20020829 |
| Rho signaling pathway targeted to promote spinal cord repair. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020801 |
| Effects of cell tension on the small GTPase Rac. | The Journal of cell biology 20020708 |
| Possible interrelationship between changes in F-actin and myosin II, protein phosphorylation, and cell volume regulation in Ehrlich ascites tumor cells. | Experimental cell research 20020701 |
| Inhibition of Rho-kinase induces alphaB-crystallin expression in lens epithelial cells. | Biochemical and biophysical research communications 20020628 |
| Rho family GTP binding proteins are involved in the regulatory volume decrease process in NIH3T3 mouse fibroblasts. | The Journal of physiology 20020615 |
| Inhibition of Rho/Rho-kinase signaling downregulates plasminogen activator inhibitor-1 synthesis in cultured human monocytes. | Biochimica et biophysica acta 20020612 |
| Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase. | The Biochemical journal 20020601 |
| Vasospasm following subarachnoid hemorrhage: evidence against functional upregulation of Rho kinase constrictor pathway. | Neurological research 20020601 |
| Phosphatidylinositol 4-phosphate 5-kinase is essential for ROCK-mediated neurite remodeling. | The Journal of biological chemistry 20020510 |
| Involvement of Rho-kinase pathway for angiotensin II-induced plasminogen activator inhibitor-1 gene expression and cardiovascular remodeling in hypertensive rats. | The Journal of pharmacology and experimental therapeutics 20020501 |
| Increased activity of calcium channels and Rho-associated kinase in the basilar artery during chronic hypertension in vivo. | Journal of hypertension 20020501 |
| Cooperativity between the Ras-ERK and Rho-Rho kinase pathways in urokinase-type plasminogen activator-stimulated cell migration. | The Journal of biological chemistry 20020405 |
| Effects of Y-27632, a Rho/Rho kinase inhibitor, on leukotriene D(4)- and histamine-induced airflow obstruction and airway microvascular leakage in guinea pigs in vivo. | Pharmacology 20020401 |
| Regulation of capacitative and noncapacitative receptor-operated Ca2+ entry by rho-kinase in tracheal smooth muscle. | American journal of respiratory cell and molecular biology 20020401 |
| Inhibition of rho-kinase-induced myristoylated alanine-rich C kinase substrate (MARCKS) phosphorylation in human neuronal cells by H-1152, a novel and specific Rho-kinase inhibitor. | Journal of neurochemistry 20020401 |
| Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection. | European journal of pharmacology 20020329 |
| Rho/ROCK pathway contributes to the activation of extracellular signal-regulated kinase/GATA-4 during myocardial cell hypertrophy. | The Journal of biological chemistry 20020308 |
| Long-term effects of benidipine on cerebral vasoreactivity in hypertensive rats. | European journal of pharmacology 20020308 |
| RhoA/Rho kinase and nitric oxide modulate the agonist-induced pulmonary artery diameter response time. | American journal of physiology. Heart and circulatory physiology 20020301 |
| The protein kinase A inhibitor H89 acts on cell morphology by inhibiting Rho kinase. | The Journal of pharmacology and experimental therapeutics 20020301 |
| Rho-kinase as a novel therapeutic target in treatment of cardiovascular diseases. | Journal of cardiovascular pharmacology 20020301 |
| Role of Rho-associated protein kinase and histamine in lysophosphatidic acid-induced airway hyperresponsiveness in guinea pigs. | Japanese journal of pharmacology 20020301 |
| Cardiac effects of a selective rho-associated kinase inhibitor, Y-27632, assessed in canine isolated, blood-perfused heart preparations. | Japanese journal of pharmacology 20020301 |
| HMG-CoA reductase inhibitors reduce interleukin-6 synthesis in human vascular smooth muscle cells. | Cardiovascular drugs and therapy 20020301 |
| HMG-CoA reductase inhibitors suppress intracellular calcium mobilization and membrane current induced by lysophosphatidylcholine in endothelial cells. | Circulation 20020226 |
| Expression and modulation of Rho kinase in human pregnant myometrium. | Molecular human reproduction 20020201 |
| Important role of Rho-kinase in the pathogenesis of cardiovascular inflammation and remodeling induced by long-term blockade of nitric oxide synthesis in rats. | Hypertension (Dallas, Tex. : 1979) 20020201 |
| Nitric oxide induces dilation of rat aorta via inhibition of rho-kinase signaling. | Hypertension (Dallas, Tex. : 1979) 20020201 |
| Circumferential stretching of saphenous vein smooth muscle enhances vasoconstrictor responses by Rho kinase-dependent pathways. | Cardiovascular research 20020101 |
| A role for the Rho-p160 Rho coiled-coil kinase axis in the chemokine stromal cell-derived factor-1alpha-induced lymphocyte actomyosin and microtubular organization and chemotaxis. | Journal of immunology (Baltimore, Md. : 1950) 20020101 |
| Thromboxane receptor signalling in human myometrial cells. | Prostaglandins & other lipid mediators 20020101 |
| Microtubule-dependent regulation of vasomotor tone requires Rho-kinase. | Journal of vascular research 20020101 |
| Rac, a small guanosine triphosphate-binding protein, and p21-activated kinase are activated during platelet spreading on collagen-coated surfaces: roles of integrin alpha(2)beta(1). | Blood 20011215 |
| Modulation of COX-2 expression by statins in human aortic smooth muscle cells. Involvement of geranylgeranylated proteins. | The Journal of biological chemistry 20011214 |
| Activation of phospholipase D in porcine tracheal smooth muscle: role of phosphatidylinositol 3-kinase and RhoA activation. | European journal of pharmacology 20011214 |
| Rho inhibits cAMP-induced translocation of aquaporin-2 into the apical membrane of renal cells. | American journal of physiology. Renal physiology 20011201 |
| Sphingosine 1-phosphate contracts canine basilar arteries in vitro and in vivo: possible role in pathogenesis of cerebral vasospasm. | Stroke 20011201 |
| Decreased penile erection in DOCA-salt and stroke prone-spontaneously hypertensive rats. | International journal of impotence research 20011201 |
| A role for a RhoA/ROCK/LIM-kinase pathway in the regulation of cytotoxic lymphocytes. | Journal of immunology (Baltimore, Md. : 1950) 20011115 |
| Rho-kinase regulates myosin II activation in MDCK cells during recovery after ATP depletion. | American journal of physiology. Renal physiology 20011101 |
| The functional role of rho and rho-associated coiled-coil forming protein kinase in eotaxin signaling of eosinophils. | Journal of immunology (Baltimore, Md. : 1950) 20011015 |
| Inhibitory effect of Y-27632, a ROCK inhibitor, on progression of rat liver fibrosis in association with inactivation of hepatic stellate cells. | Journal of hepatology 20011001 |
| Thrombin-induced activation of RhoA in platelet shape change. | Biochemical and biophysical research communications 20010914 |
| Effects of Y-27632 on acetylcholine-induced contraction of intact and permeabilized intrapulmonary bronchial smooth muscles in rats. | European journal of pharmacology 20010907 |
| Effect of Rho-kinase inhibition on vasoconstriction in the penile circulation. | Journal of applied physiology (Bethesda, Md. : 1985) 20010901 |
| Dependency of detrusor contractions on calcium sensitization and calcium entry through LOE-908-sensitive channels. | British journal of pharmacology 20010901 |
| Role of Rho-associated protein kinase in tone and calcium sensitivity of cannulated rat mesenteric small arteries. | Experimental physiology 20010901 |
| Role of lysophosphatidylcholine in the desensitization of beta-adrenergic receptors by Ca(2+) sensitization in tracheal smooth muscle. | American journal of respiratory cell and molecular biology 20010901 |
| Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms. | The Journal of biological chemistry 20010803 |
| Alpha1-adrenoceptor-Gq-RhoA signaling is upregulated to increase myofibrillar Ca2+ sensitivity in failing hearts. | American journal of physiology. Heart and circulatory physiology 20010801 |
| Oxytocin and lysophosphatidic acid induce stress fiber formation in human myometrial cells via a pathway involving Rho-kinase. | Biology of reproduction 20010801 |
| Involvement of Rho-kinase and the actin filament network in angiotensin II-induced contraction and extracellular signal-regulated kinase activity in intact rat mesenteric resistance arteries. | Arteriosclerosis, thrombosis, and vascular biology 20010801 |
| Inhibition of neurite extension by overexpression of individual domains of LIM kinase 1. | Journal of neurochemistry 20010801 |
| Involvement of a calcium-independent pathway in plasmin-induced platelet shape change. | Life sciences 20010713 |
| Regulation by GDI of RhoA/Rho-kinase-induced Ca2+ sensitization of smooth muscle myosin II. | American journal of physiology. Cell physiology 20010701 |
| Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats. | British journal of pharmacology 20010701 |
| Distinct pathways of Ca(2+) sensitization in porcine coronary artery: effects of Rho-related kinase and protein kinase C inhibition on force and intracellular Ca(2+). | Circulation research 20010622 |
| Thiophosphorylation-induced Ca(2+) sensitization of guinea-pig ileum contractility is not mediated by Rho-associated kinase. | The Journal of physiology 20010615 |
| Y-27632, an inhibitor of Rho-associated kinases, prevents tyrosine phosphorylation of focal adhesion kinase and paxillin induced by bombesin: dissociation from tyrosine phosphorylation of p130(CAS). | Experimental cell research 20010610 |
| Human urotensin II-induced contraction and arterial smooth muscle cell proliferation are mediated by RhoA and Rho-kinase. | Circulation research 20010608 |
| Possible involvement of Rho kinase in Ca2+ sensitization and mobilization by MCh in tracheal smooth muscle. | American journal of physiology. Lung cellular and molecular physiology 20010601 |
| Y-27632, an inhibitor of Rho-kinase, antagonizes noradrenergic contractions in the rabbit and human penile corpus cavernosum. | British journal of pharmacology 20010601 |
| Reduction of intraocular pressure by topical administration of an inhibitor of the Rho-associated protein kinase. | Current eye research 20010601 |
| Involvement of Rho-kinase and tyrosine kinase in hypotonic stress-induced ATP release in bovine aortic endothelial cells. | The Journal of physiology 20010501 |
| Evidence that Rho-kinase activity contributes to cerebral vascular tone in vivo and is enhanced during chronic hypertension: comparison with protein kinase C. | Circulation research 20010427 |
| Rho-Rho kinase is involved in smooth muscle cell migration through myosin light chain phosphorylation-dependent and independent pathways. | Atherosclerosis 20010401 |
| Rho and Rac but not Cdc42 regulate endothelial cell permeability. | Journal of cell science 20010401 |
| Modulation of aqueous humor outflow facility by the Rho kinase-specific inhibitor Y-27632. | Investigative ophthalmology & visual science 20010401 |
| Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells. | Japanese journal of cancer research : Gann 20010401 |
| A selective ROCK inhibitor, Y27632, prevents dimethylnitrosamine-induced hepatic fibrosis in rats. | Journal of hepatology 20010401 |
| Myotonic dystrophy protein kinase phosphorylates the myosin phosphatase targeting subunit and inhibits myosin phosphatase activity. | FEBS letters 20010330 |
| Inhibition of intrahepatic metastasis of human hepatocellular carcinoma by Rho-associated protein kinase inhibitor Y-27632. | Hepatology (Baltimore, Md.) 20010301 |
| Alternatives to Viagra. | Trends in molecular medicine 20010301 |
| Rho-kinase is involved in the sustained phosphorylation of myosin and the irreversible platelet aggregation induced by PAR1 activating peptide. | Thrombosis and haemostasis 20010301 |
| RhoA/rho-associated kinase mediates fibroblast contractile force generation. | Biochemical and biophysical research communications 20010209 |
| Small GTPase Rho regulates thrombin-induced platelet aggregation. | Biochemical and biophysical research communications 20010202 |
| Enhancement of Rho/Rho-kinase system in regulation of vascular smooth muscle contraction in tachycardia-induced heart failure. | Cardiovascular research 20010201 |
| Arachidonic acid-induced Ca2+ sensitization of smooth muscle contraction through activation of Rho-kinase. | Pflugers Archiv : European journal of physiology 20010201 |
| Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase. | The Journal of biological chemistry 20010105 |
| Smooth muscle differentiation marker gene expression is regulated by RhoA-mediated actin polymerization. | The Journal of biological chemistry 20010105 |
| Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. | Investigative ophthalmology & visual science 20010101 |
| Leukotriene C(4) enhances the contraction of porcine tracheal smooth muscle through the activation of Y-27632, a rho kinase inhibitor, sensitive pathway. | British journal of pharmacology 20010101 |
| Microtubule disruption modulates the Rho-kinase pathway in vascular smooth muscle. | Journal of muscle research and cell motility 20010101 |
| Importance of Rho-kinase-mediated phosphorylation of myosin light chain in vasospasm. | Acta neurochirurgica. Supplement 20010101 |
| Enhanced relaxation to the rho-kinase inhibitor Y-27632 in mesenteric arteries from mineralocorticoid hypertensive rats. | Pharmacology 20010101 |
| Specificity and mechanism of action of some commonly used protein kinase inhibitors. | The Biochemical journal 20001001 |
| Y-27632 potentiates relaxant effects of beta 2-adrenoceptor agonists in bovine tracheal smooth muscle. | European journal of pharmacology 20000211 |
| Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. | Nature 19971030 |
| Androgens induce nongenomic stimulation of colonic contractile activity through induction of calcium sensitization and phosphorylation of LC20 and CPI-17. | Molecular endocrinology (Baltimore, Md.) |