Phosphonic acid, P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, P,P,P',P'-tetraethyl ester
| Title | Journal |
|---|---|
| Profiling of bisphenol S towards nuclear receptors activities in human reporter cell lines. | Toxicology letters 20171105 |
| Human pregnane X receptor is activated by dibenzazepine carbamate-based inhibitors of constitutive androstane receptor. | Archives of toxicology 20170601 |
| Acetylated deoxycholic (DCA) and cholic (CA) acids are potent ligands of pregnane X (PXR) receptor. | Toxicology letters 20170104 |
| Transactivation Assays to Assess Canine and Rodent Pregnane X Receptor (PXR) and Constitutive Androstane Receptor (CAR) Activation. | PloS one 20160101 |
| Analysis of Glycogen Synthase Kinase Inhibitors That Regulate Cytochrome P450 Expression in Primary Human Hepatocytes by Activation of β-Catenin, Aryl Hydrocarbon Receptor and Pregnane X Receptor Signaling. | Toxicological sciences : an official journal of the Society of Toxicology 20151101 |
| Improved assays for xenosensor activation based on reverse transfection. | Toxicology in vitro : an international journal published in association with BIBRA 20151001 |
| Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differently. | Toxicology and applied pharmacology 20150401 |
| Notoginsenoside R1 attenuates experimental inflammatory bowel disease via pregnane X receptor activation. | The Journal of pharmacology and experimental therapeutics 20150201 |
| Allyl isothiocyanate (AITC) inhibits pregnane X receptor (PXR) and constitutive androstane receptor (CAR) activation and protects against acetaminophen- and amiodarone-induced cytotoxicity. | Archives of toxicology 20150101 |
| U0126, a mitogen-activated protein kinase kinase 1 and 2 (MEK1 and 2) inhibitor, selectively up-regulates main isoforms of CYP3A subfamily via a pregnane X receptor (PXR) in HepG2 cells. | Archives of toxicology 20141201 |
| Affinity purification using recombinant PXR as a tool to characterize environmental ligands. | Environmental toxicology 20140201 |
| Polycyclic aromatic hydrocarbons stimulate human CYP3A4 promoter activity via PXR. | Toxicology letters 20131024 |
| The novel antibacterial compound walrycin A induces human PXR transcriptional activity. | Toxicological sciences : an official journal of the Society of Toxicology 20120501 |
| Aflatoxins upregulate CYP3A4 mRNA expression in a process that involves the PXR transcription factor. | Toxicology letters 20110828 |
| Pregnane X receptor PXR activates the GADD45beta gene, eliciting the p38 MAPK signal and cell migration. | The Journal of biological chemistry 20110204 |
| Identification of clinically used drugs that activate pregnane X receptors. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
| Regulation of drug resistance by human pregnane X receptor in breast cancer. | Cancer biology & therapy 20090701 |
| Up-regulation of P-glycoprotein by HIV protease inhibitors in a human brain microvessel endothelial cell line. | Journal of neuroscience research 20090301 |
| N-1H-benzimidazol-5-ylbenzenesulfonamide derivatives as potent hPXR agonists. | Bioorganic & medicinal chemistry 20080401 |
| Azole antimycotics differentially affect rifampicin-induced pregnane X receptor-mediated CYP3A4 gene expression. | Drug metabolism and disposition: the biological fate of chemicals 20080201 |
| Human pregnane X receptor and resistance to chemotherapy in prostate cancer. | Cancer research 20071101 |
| Discovery of a highly active ligand of human pregnane x receptor: a case study from pharmacophore modeling and virtual screening to 'in vivo' biological activity. | Molecular pharmacology 20070901 |
| In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
| Identification of new human pregnane X receptor ligands among pesticides using a stable reporter cell system. | Toxicological sciences : an official journal of the Society of Toxicology 20060601 |
| Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase. | The Journal of biological chemistry 20041008 |
| Coactivator binding promotes the specific interaction between ligand and the pregnane X receptor. | Journal of molecular biology 20030822 |
| The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. | Endocrine reviews 20021001 |
| The PXR ligand-binding domain: how to be picky and promiscuous at the same time. | Trends in pharmacological sciences 20010901 |
| The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity. | Science (New York, N.Y.) 20010622 |
| Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. | The Journal of biological chemistry 20000519 |
| The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution. | Molecular endocrinology (Baltimore, Md.) 20000101 |