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Purine

CAS No.:
120-73-0
Catalog Number:
AG000Q1O
Molecular Formula:
C5H4N4
Molecular Weight:
120.1121
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
98%(HPLC)
In Stock USA
United States
$101
- +
1g
98%(HPLC)
In Stock USA
United States
$196
- +
5g
98%(HPLC)
In Stock USA
United States
$557
- +
10g
98%(HPLC)
In Stock USA
United States
$910
- +
25g
98%(HPLC)
In Stock USA
United States
$1723
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Product Description
Catalog Number:
AG000Q1O
Chemical Name:
Purine
CAS Number:
120-73-0
Molecular Formula:
C5H4N4
Molecular Weight:
120.1121
MDL Number:
MFCD00079221
IUPAC Name:
7H-purine
InChI:
InChI=1S/C5H4N4/c1-4-5(8-2-6-1)9-3-7-4/h1-3H,(H,6,7,8,9)
InChI Key:
KDCGOANMDULRCW-UHFFFAOYSA-N
SMILES:
c1ncc2c(n1)[nH]cn2
EC Number:
204-421-2
UNII:
W60KTZ3IZY
NSC Number:
753
Properties
Complexity:
105  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
120.044g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
120.115g/mol
Monoisotopic Mass:
120.044g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
54.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.4  
Literature
Title Journal
9H-purine scaffold reveals induced-fit pocket plasticity of the BRD9 bromodomain. Journal of medicinal chemistry 20150326
1,3-Dialkyl-substituted tetrahydropyrimido[1,2-f]purine-2,4-diones as multiple target drugs for the potential treatment of neurodegenerative diseases. Bioorganic & medicinal chemistry 20131201
Anti-inflammatory effects of purine nucleosides, adenosine and inosine, in a mouse model of pleurisy: evidence for the role of adenosine A2 receptors. Purinergic signalling 20121201
Effects of catalase and 1400W on the number of interleukin-4 and interferon-γ secreting spleen cells in mice injected with ovalbumin and alum. Immunopharmacology and immunotoxicology 20121201
Retreatment with purine analogs in patients with chronic lymphocytic leukemia. Leukemia research 20121201
S-allyl derivatives of 6-mercaptopurine are highly potent drugs against human B-CLL through synergism between 6-mercaptopurine and allicin. Leukemia research 20121201
The evolution of catalytic residues and enzyme mechanism within the bacterial nucleoside phosphorylase superfamily 1. Gene 20121201
The investigation of the binding of 6-mercaptopurine to site I on human serum albumin. The protein journal 20121201
Investigations into specificity of azepinomycin for inhibition of guanase: discrimination between the natural heterocyclic inhibitor and its synthetic nucleoside analogues. Bioorganic & medicinal chemistry letters 20121201
Targeting conserved water molecules: design of 4-aryl-5-cyanopyrrolo[2,3-d]pyrimidine Hsp90 inhibitors using fragment-based screening and structure-based optimization. Bioorganic & medicinal chemistry 20121115
Trimeric purine nucleoside phosphorylase: exploring postulated one-third-of-the-sites binding in the transition state. Bioorganic & medicinal chemistry 20121115
Synthesis of 6-amino-2-vinylpurine derivatives for cross-linking and evaluation of the reactivity. Bioorganic & medicinal chemistry letters 20121115
Poly(alizarin red)/graphene modified glassy carbon electrode for simultaneous determination of purine and pyrimidine. Analytica chimica acta 20121108
Structural basis of substrate specificity and selectivity of murine cytosolic 5'-nucleotidase III. Journal of molecular biology 20121102
Inhibition of xanthine oxidase reduces wasting and improves outcome in a rat model of cancer cachexia. International journal of cancer 20121101
Astrocyte origin of activity-dependent release of ATP and glutamate in hippocampal slices: real-time measurement utilizing microelectrode biosensors. British journal of pharmacology 20121101
Synergism between clofarabine and decitabine through p53R2: a pharmacodynamic drug-drug interaction modeling. Leukemia research 20121101
A triple-helix forming oligonucleotide targeting genomic DNA fails to induce mutation. Mutagenesis 20121101
Metabolite target analysis of human urine combined with pattern recognition techniques for the study of symptomatic gout. Molecular bioSystems 20121101
Quantitation of intracellular purine intermediates in different Corynebacteria using electrospray LC-MS/MS. Analytical and bioanalytical chemistry 20121101
Pharmacokinetic evaluation and therapeutic activity of bendamustine in B-cell lymphoid malignancies. Expert opinion on drug metabolism & toxicology 20121101
A perspective on diet and gout. Advances in chronic kidney disease 20121101
Genetic disorders resulting in hyper- or hypouricemia. Advances in chronic kidney disease 20121101
The rheumatology of gout. Advances in chronic kidney disease 20121101
Advanced kidney failure and hyperuricemia. Advances in chronic kidney disease 20121101
Fatty acids change the conformation of uncoupling protein 1 (UCP1). The Journal of biological chemistry 20121026
Mild hyperhomocysteinemia alters extracellular adenine metabolism in rat brain. Neuroscience 20121025
Effect of ginseng polysaccharide on the urinary excretion of type 2 diabetic rats studied by liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121015
General acid-base catalysis mediated by nucleobases in the hairpin ribozyme. Journal of the American Chemical Society 20121010
Serum metabolomics in a Helicobacter hepaticus mouse model of inflammatory bowel disease reveal important changes in the microbiome, serum peptides, and intermediary metabolism. Journal of proteome research 20121005
Dynamics and efficiency of hole transport in LNA:DNA hybrid diblock oligomers. Journal of the American Chemical Society 20121003
An efficient antigene activity and antiproliferative effect by targeting the Bcl-2 or survivin gene with triplex forming oligonucleotides containing a W-shaped nucleoside analogue (WNA-βT). Organic & biomolecular chemistry 20121003
Effects of chronic guanosine treatment on hippocampal damage and cognitive impairment of rats submitted to chronic cerebral hypoperfusion. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20121001
Reduced serum uric acid levels in neuromyelitis optica: serum uric acid levels are reduced during relapses in NMO. Acta neurologica Scandinavica 20121001
Reactions of benzene oxide, a reactive metabolite of benzene, with model nucleophiles and DNA. Xenobiotica; the fate of foreign compounds in biological systems 20121001
Effect of roughage to concentrate ratio of sweet sorghum (Sorghum biclor L. Moench) bagasse-based complete diet on nutrient utilization and microbial N supply in lambs. Tropical animal health and production 20121001
Genotype frequencies of drug-metabolizing enzymes responsible for purine and pyrimidine antagonists in a healthy Asian-Indian population. Biochemical genetics 20121001
Developmental lead effects on behavior and brain gene expression in male and female BALB/cAnNTac mice. Neurotoxicology 20121001
Modulation of lymphocyte function in vivo via inhibition of calcineurin or purine synthesis in patients with atopic dermatitis. The Journal of investigative dermatology 20121001
Protection of dopaminergic cells by urate requires its accumulation in astrocytes. Journal of neurochemistry 20121001
Tautomeric purine forms of 2-amino-6-chloropurine (N9H10 and N7H10): structures, vibrational assignments, NBO analysis, hyperpolarizability, HOMO-LUMO study using B3 based density functional calculations. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001
A(₂B)AR expression in non-immune cells plays an important role in the development of murine colitis. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20121001
Hydroxynonenal, a lipid peroxidation end product, stimulates uncoupling protein activity in Acanthamoeba castellanii mitochondria; the sensitivity of the inducible activity to purine nucleotides depends on the membranous ubiquinone redox state. Journal of bioenergetics and biomembranes 20121001
Structural and kinetic studies of Schistosoma mansoni adenylate kinases. Molecular and biochemical parasitology 20121001
MutT homolog-1 attenuates oxidative DNA damage and delays photoreceptor cell death in inherited retinal degeneration. The American journal of pathology 20121001
Purine anti-metabolite attenuates nuclear factor κB and related pro-inflammatory cytokines in experimental vasospasm. Acta neurochirurgica 20121001
Purinergic signaling in the airways. Pharmacological reviews 20121001
The Escherichia coli RlmN methyltransferase is a dual-specificity enzyme that modifies both rRNA and tRNA and controls translational accuracy. RNA (New York, N.Y.) 20121001
Nutrient utilization, ruminal fermentation, microbial abundances, and milk yield and composition in dairy goats fed diets including tomato and cucumber waste fruits. Journal of dairy science 20121001
Discovery of 6-[4-(6-nitroxyhexanoyl)piperazin-1-yl)]-9H-purine, as pharmacological post-conditioning agent. Bioorganic & medicinal chemistry 20121001
Neuronal and extraneuronal release of ATP and NAD(+) in smooth muscle. IUBMB life 20121001
Synthesis and biological evaluation of novel homochiral carbocyclic nucleosides from 1-amino-2-indanols. Bioorganic & medicinal chemistry 20121001
Enzyme-coupled assays for simultaneous detection of nanomolar ATP, ADP, AMP, adenosine, inosine and pyrophosphate concentrations in extracellular fluids. Biochimica et biophysica acta 20121001
Lack of expression of MTAP in uncommon T-cell lymphomas. Clinical lymphoma, myeloma & leukemia 20121001
GC-TOF-MS- and CE-TOF-MS-based metabolic profiling of cheonggukjang (fast-fermented bean paste) during fermentation and its correlation with metabolic pathways. Journal of agricultural and food chemistry 20120926
Curvopeptin: a new lanthionine-containing class III lantibiotic and its co-substrate promiscuous synthetase. Chembiochem : a European journal of chemical biology 20120924
Simultaneous analysis of the main markers of nitrogen status in dairy cow's urine using hydrophilic interaction chromatography and tandem mass spectrometry detection. Journal of chromatography. A 20120921
H-bonds superstructures built by aquacomplexes and an azapurine derivative: a case of molecular recognition. Dalton transactions (Cambridge, England : 2003) 20120914
Discovery of (2S)-1-[4-(2-{6-amino-8-[(6-bromo-1,3-benzodioxol-5-yl)sulfanyl]-9H-purin-9-yl}ethyl)piperidin-1-yl]-2-hydroxypropan-1-one (MPC-3100), a purine-based Hsp90 inhibitor. Journal of medicinal chemistry 20120913
Novel coumarin derivatives containing 1,2,4-triazole, 4,5-dicyanoimidazole and purine moieties: synthesis and evaluation of their cytostatic activity. Molecules (Basel, Switzerland) 20120912
Photosensitizing properties of biopterin and its photoproducts using 2'-deoxyguanosine 5'-monophosphate as an oxidizable target. Physical chemistry chemical physics : PCCP 20120907
Fludarabine and cladribine induce changes in surface proteins on human B-lymphoid cell lines involved with apoptosis, cell survival, and antitumor immunity. Journal of proteome research 20120907
A stereoselective approach to β-L-arabino nucleoside analogues: synthesis and cyclization of acyclic 1',2'-syn N,O-acetals. The Journal of organic chemistry 20120907
Copper-catalyzed synthesis of purine-fused polycyclics. Organic letters 20120907
Hypouricemic effects of novel concentrative nucleoside transporter 2 inhibitors through suppressing intestinal absorption of purine nucleosides. European journal of pharmacology 20120905
Can ex vivo evaluation (testing) predict the sensitivity of CLL cells to therapy with purine analogs in conjunction with an alkylating agent? A comparison of in vivo and ex vivo responses to treatment. Medical oncology (Northwood, London, England) 20120901
Purines as potential morphogens during embryonic development. Purinergic signalling 20120901
Clofarabine in pediatric acute leukemia: current findings and issues. Pediatric blood & cancer 20120901
G protein-coupled adenosine (P1) and P2Y receptors: ligand design and receptor interactions. Purinergic signalling 20120901
Carbocyclic thymidine derivatives efficiently inhibit Plasmodium falciparum thymidylate kinase (PfTMK). Parasitology international 20120901
Preliminary evidence for the dedifferentiation of RAW 264.7 cells into mesenchymal progenitor-like cells by a purine analog. Tissue engineering. Part A 20120901
Molecular and functional properties of P2X receptors--recent progress and persisting challenges. Purinergic signalling 20120901
Purine-rich foods intake and recurrent gout attacks. Annals of the rheumatic diseases 20120901
Medical therapy and mucosal healing. Current drug targets 20120901
Malaria parasite type 4 equilibrative nucleoside transporters (ENT4) are purine transporters with distinct substrate specificity. The Biochemical journal 20120901
Functional characterization of UCP1 in mammalian HEK293 cells excludes mitochondrial uncoupling artefacts and reveals no contribution to basal proton leak. Biochimica et biophysica acta 20120901
Graft-versus-host disease reduces regulatory T-cell migration into the tumour tissue. Immunology 20120901
Gene expression profile of early in vitro biofilms of Streptococcus pneumoniae. Microbiology and immunology 20120901
Successful treatment with azathioprine of relapsing Rosai-Dorfman disease of the central nervous system. Journal of neurosurgery 20120901
Mycophenolate mofetil inhibits hepatitis C virus replication in human hepatic cells. Virus research 20120901
Gene expression profiles of vitrified in vitro- and in vivo-derived bovine blastocysts. Molecular reproduction and development 20120901
Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells. Cancer biology & therapy 20120901
Transition state analogue inhibitors of human methylthioadenosine phosphorylase and bacterial methylthioadenosine/S-adenosylhomocysteine nucleosidase incorporating acyclic ribooxacarbenium ion mimics. Bioorganic & medicinal chemistry 20120901
Biochemical mapping of human NEIL1 DNA glycosylase and AP lyase activities. DNA repair 20120901
Cytosolic clearance of replication-deficient mutants reveals Francisella tularensis interactions with the autophagic pathway. Autophagy 20120901
Folylpoly-glutamate synthetase expression is associated with tumor response and outcome from pemetrexed-based chemotherapy in malignant pleural mesothelioma. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120901
Smart portable electrophoresis instrument based on multipurpose microfluidic chips with electrochemical detection. Electrophoresis 20120901
Integrative genomic analysis identifies isoleucine and CodY as regulators of Listeria monocytogenes virulence. PLoS genetics 20120901
2-Chloro-N-ethyl-9-isopropyl-9H-purin-6-amine. Acta crystallographica. Section E, Structure reports online 20120901
Significance of mycophenolate monitoring in liver transplant recipients: toward the cut-off level. Transplantation proceedings 20120901
Extent of intramolecular π-stacks in aqueous solution in mixed-ligand copper(II) complexes formed by heteroaromatic amines and several 2-aminopurine derivatives of the antivirally active nucleotide analog 9-[2-(phosphonomethoxy)ethyl]adenine (PMEA). Chemistry & biodiversity 20120901
Leishmania metacyclogenesis is promoted in the absence of purines. PLoS neglected tropical diseases 20120901
Click fleximers: a modular approach to purine base-expanded ribonucleoside analogues. Organic & biomolecular chemistry 20120828
7-Substituted 8-aza-7-deazaadenosines for modification of the siRNA major groove. Organic & biomolecular chemistry 20120828
Inhibition of pokeweed antiviral protein (PAP) by turnip mosaic virus genome-linked protein (VPg). The Journal of biological chemistry 20120824
Multicomponent assembly of proposed DNA precursors in water. Journal of the American Chemical Society 20120822
Structural and biochemical characterization of human adenylosuccinate lyase (ADSL) and the R303C ADSL deficiency-associated mutation. Biochemistry 20120821
Low-level lead exposure and the prevalence of gout: an observational study. Annals of internal medicine 20120821
Human SLC2A9a and SLC2A9b isoforms mediate electrogenic transport of urate with different characteristics in the presence of hexoses. American journal of physiology. Renal physiology 20120815
Haplotypes across the human caveolin 1 gene upstream purine complex significantly alter gene expression: implication in neurodegenerative disorders. Gene 20120815
Identification and dynamic analysis of the purine alkaloids in rat plasma after oral administration of green tea by liquid chromatography hybrid ion trap time-of-flight mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120815
Metabolic labeling of DNA by purine analogues in vivo. Chembiochem : a European journal of chemical biology 20120813
Surface-enhanced Raman scattering of whole human blood, blood plasma, and red blood cells: cellular processes and bioanalytical sensing. The journal of physical chemistry. B 20120809
Analysis of urinary metabolic signatures of early hepatocellular carcinoma recurrence after surgical removal using gas chromatography-mass spectrometry. Journal of proteome research 20120803
The effect of depurinized milk draught diet on rat serum uric acid, lipid status and haematological parameters. Journal of animal physiology and animal nutrition 20120801
Role of the adenosine(2A) receptor-epoxyeicosatrienoic acid pathway in the development of salt-sensitive hypertension. Prostaglandins & other lipid mediators 20120801
Density functional study on the derivatives of purine. Journal of molecular modeling 20120801
Tumor metabolism as modulator of immune response and tumor progression. Seminars in cancer biology 20120801
Cerebellar abnormalities in purine nucleoside phosphorylase deficient mice. Neurobiology of disease 20120801
Genetic damage induced by organic extract of coke oven emissions on human bronchial epithelial cells. Toxicology in vitro : an international journal published in association with BIBRA 20120801
Crystal structure of tandem ACT domain-containing protein ACTP from Galdieria sulphuraria. Proteins 20120801
Predictive factors for poor peripheral blood stem cell mobilization and peak CD34(+) cell count to guide pre-emptive or immediate rescue mobilization. Cytotherapy 20120801
Hepatic hemodynamics in 24 patients with nodular regenerative hyperplasia and symptomatic portal hypertension. Journal of gastroenterology and hepatology 20120801
C-C cross-coupling reactions of O6-alkyl-2-haloinosine derivatives and a one-pot cross-coupling/O6-deprotection procedure. Chemistry, an Asian journal 20120801
T- and B-cell defects in a novel purine nucleoside phosphorylase mutation. The Journal of allergy and clinical immunology 20120801
Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors. Pharmacology, biochemistry, and behavior 20120801
Urate in Parkinson's disease: more than a biomarker? Current neurology and neuroscience reports 20120801
Functional significance of four successive glycine residues in the pyrophosphate binding loop of fungal 6-oxopurine phosphoribosyltransferases. Protein science : a publication of the Protein Society 20120801
Regioselective enzymatic undecylenoylation of 8-chloroadenosine and its analogs with biomass-based 2-methyltetrahydrofuran as solvent. Bioresource technology 20120801
Unraveling ultrafast dynamics in photoexcited aniline. Journal of the American Chemical Society 20120801
Purine salvage in Leishmania: complex or simple by design? Trends in parasitology 20120801
Remodeling of cytokinin metabolism at infection sites of Colletotrichum graminicola on maize leaves. Molecular plant-microbe interactions : MPMI 20120801
Discovery and optimization of novel purines as potent and selective CB2 agonists. Bioorganic & medicinal chemistry letters 20120801
Lesch-Nyhan syndrome: mRNA expression of HPRT in patients with enzyme proven deficiency of HPRT and normal HPRT coding region of the DNA. Molecular genetics and metabolism 20120801
Assaying the proton transport and regulation of UCP1 using solid supported membranes. European biophysics journal : EBJ 20120801
Structure and mechanism of purine-binding riboswitches. Quarterly reviews of biophysics 20120801
Sustainable synthesis and automated deposition: an accessible discovery screening library of fragment-like purines. Molecular diversity 20120801
Molecular analysis of mutants of the Neurospora adenylosuccinate synthetase locus. Journal of genetics 20120801
Continuous enzyme-coupled assay of phosphate- or pyrophosphate-releasing enzymes. BioTechniques 20120801
The pendulum model for genome compositional dynamics: from the four nucleotides to the twenty amino acids. Genomics, proteomics & bioinformatics 20120801
Strand-biased gene distribution in bacteria is related to both horizontal gene transfer and strand-biased nucleotide composition. Genomics, proteomics & bioinformatics 20120801
Catalytic zinc site and mechanism of the metalloenzyme PR-AMP cyclohydrolase. Biochemistry 20120724
The mechanism of guanine alkylation by nitrogen mustards: a computational study. The Journal of organic chemistry 20120720
A dramatic concentration effect on the stereoselectivity of N-glycosylation for the synthesis of 2'-deoxy-β-ribonucleosides. Chemical communications (Cambridge, England) 20120718
The electronic spectra and the H-bonding pattern of the sulfur and selenium substituted guanines. Journal of computational chemistry 20120715
Anti-herpes simplex virus efficacies of 2-aminobenzamide derivatives as novel HSP90 inhibitors. Bioorganic & medicinal chemistry letters 20120715
Cladribine, but not fludarabine, added to daunorubicin and cytarabine during induction prolongs survival of patients with acute myeloid leukemia: a multicenter, randomized phase III study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120710
Molecular biology of pancreatic cancer: how useful is it in clinical practice? JOP : Journal of the pancreas 20120710
Nafion-CNT coated carbon-fiber microelectrodes for enhanced detection of adenosine. The Analyst 20120707
Synthetic control of framework zinc purinate crystallisation and properties of a large pore, decorated, mixed-linker RHO-type ZIF. Chemical communications (Cambridge, England) 20120707
Purinergic signaling promotes proliferation of adult mouse subventricular zone cells. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120704
Novel features in the evolution of adenylosuccinate lyase deficiency. European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120701
Adenosine deaminase activity in serum and lymphocytes of rats infected with Sporothrix schenckii. Mycopathologia 20120701
One-step enzymatic synthesis of nucleosides from low water-soluble purine bases in non-conventional media. Bioresource technology 20120701
The inhibitors of nucleotide biosynthesis leflunomide, FK778, and mycophenolic acid activate hepatitis B virus replication in vitro. Hepatology (Baltimore, Md.) 20120701
Oxidatively generated DNA lesions as potential biomarkers of in vivo oxidative stress. Current molecular medicine 20120701
Methylation capacity in children with severe cerebral palsy. European journal of clinical investigation 20120701
Enzymology of tRNA modification in the bacterial MnmEG pathway. Biochimie 20120701
The role of the NTPDase enzyme family in parasites: what do we know, and where to from here? Parasitology 20120701
Reversine, a 2,6-disubstituted purine, as an anti-cancer agent in differentiated and undifferentiated thyroid cancer cells. Pharmaceutical research 20120701
Phosphorylation of deoxycytidine kinase on Ser-74: impact on kinetic properties and nucleoside analog activation in cancer cells. Biochemical pharmacology 20120701
Next-generation sequencing offers new insights into DNA degradation. Trends in biotechnology 20120701
Lead optimization of purine based orally bioavailable Mps1 (TTK) inhibitors. Bioorganic & medicinal chemistry letters 20120701
Defining combined immunodeficiency. The Journal of allergy and clinical immunology 20120701
8-17 DNAzyme modified with purine analogs in its catalytic core: the conservation of the five-membered moieties of purine residues. Bioorganic & medicinal chemistry letters 20120701
Effect of incremental flaxseed supplementation of an herbage diet on methane output and ruminal fermentation in continuous culture. Journal of dairy science 20120701
Motor neurone disease in molybdenum-deficient sheep fed the endogenous purine xanthosine: possible mechanism for Tribulus staggers. Australian veterinary journal 20120701
DNA triplex structures in neurodegenerative disorder, Friedreich's ataxia. Journal of biosciences 20120701
Adult T-cell leukemia/lymphoma. The Gulf journal of oncology 20120701
Metabolomic fingerprint reveals that metformin impairs one-carbon metabolism in a manner similar to the antifolate class of chemotherapy drugs. Aging 20120701
Nucleoside transporters: biological insights and therapeutic applications. Future medicinal chemistry 20120701
[The first case of adenine phosphoribosyltransferase deficiency with APRT*Q0 (M1I) mutation in Japan]. Hinyokika kiyo. Acta urologica Japonica 20120701
Acyclic immucillin phosphonates: second-generation inhibitors of Plasmodium falciparum hypoxanthine-guanine-xanthine phosphoribosyltransferase. Chemistry & biology 20120622
Fluorescent C-linked C8-aryl-guanine probe for distinguishing syn from anti structures in duplex DNA. Chemical research in toxicology 20120618
Esterase inhibitors as ester-containing drug stabilizers and their hydrolytic products: potential contributors to the matrix effects on bioanalysis by liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20120615
Synthesis and characterization of 2'-C-Me branched C-nucleosides as HCV polymerase inhibitors. Bioorganic & medicinal chemistry letters 20120615
Synthesis and antiviral activity of certain second generation methylenecyclopropane nucleosides. Bioorganic & medicinal chemistry 20120615
X-ray spectroscopy of heterocyclic biochemicals: xanthine, hypoxanthine, and caffeine. The journal of physical chemistry. A 20120614
Gas-phase studies of purine 3-methyladenine DNA glycosylase II (AlkA) substrates. Journal of the American Chemical Society 20120613
Structure-activity relationship of a cold-adapted purine nucleoside phosphorylase by site-directed mutagenesis. Enzyme and microbial technology 20120610
New determinants in the catalytic mechanism of nucleoside hydrolases from the structures of two isozymes from Sulfolobus solfataricus. Biochemistry 20120605
Transcriptional profile of GTP-mediated differentiation of C2C12 skeletal muscle cells. Purinergic signalling 20120601
Spectrum of neurologic complications in chronic lymphocytic leukemia. Clinical lymphoma, myeloma & leukemia 20120601
Non-infectious lung disease in patients with adenosine deaminase deficient severe combined immunodeficiency. Journal of clinical immunology 20120601
An exon-specific U1 small nuclear RNA (snRNA) strategy to correct splicing defects. Human molecular genetics 20120601
Novel molecular targets regulated by tumor suppressors microRNA-1 and microRNA-133a in bladder cancer. International journal of oncology 20120601
Novel and emerging drugs for rarer chronic lymphoid leukaemias. Current cancer drug targets 20120601
Novel and emerging drugs for acute lymphoblastic leukemia. Current cancer drug targets 20120601
Polymorphism of genes involved in purine metabolism (XDH, AOX1, MOCOS) in kidney transplant recipients receiving azathioprine. Therapeutic drug monitoring 20120601
The second sodium pump: from the function to the gene. Pflugers Archiv : European journal of physiology 20120601
Exploring purine N7 interactions via atomic mutagenesis: the group I ribozyme as a case study. RNA (New York, N.Y.) 20120601
Facially-selective thymine-thymine photodimerization in TTT triads. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20120601
Effects of long-term experimental diabetes on adrenal gland growth and phosphoribosyl pyrophosphate formation in growth hormone-deficient dwarf rats. International journal of experimental pathology 20120601
Defective B cell tolerance in adenosine deaminase deficiency is corrected by gene therapy. The Journal of clinical investigation 20120601
Usefulness of material recovered from distal embolic protection devices after carotid angioplasty for proteomic studies. Journal of vascular and interventional radiology : JVIR 20120601
Formylglycinamide ribonucleotide amidotransferase from Salmonella typhimurium: role of ATP complexation and the glutaminase domain in catalytic coupling. Acta crystallographica. Section D, Biological crystallography 20120601
A model for 3-methyladenine recognition by 3-methyladenine DNA glycosylase I (TAG) from Staphylococcus aureus. Acta crystallographica. Section F, Structural biology and crystallization communications 20120601
Genome-wide functional profiling identifies genes and processes important for zinc-limited growth of Saccharomyces cerevisiae. PLoS genetics 20120601
Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement. PLoS genetics 20120601
Gram-scale chemical synthesis of 2'-deoxynucleoside-5'-o-triphosphates. Current protocols in nucleic acid chemistry 20120601
Caffeine-N-phthaloyl-β-alanine (1/1). Acta crystallographica. Section E, Structure reports online 20120601
Application of a fluorescent C-linked phenolic purine adduct for selective N7-metalation of DNA. The journal of physical chemistry. B 20120531
Structural and functional insights into (S)-ureidoglycine aminohydrolase, key enzyme of purine catabolism in Arabidopsis thaliana. The Journal of biological chemistry 20120525
A unified mechanism for abiotic adenine and purine synthesis in formamide. Angewandte Chemie (International ed. in English) 20120521
The CDK9 C-helix exhibits conformational plasticity that may explain the selectivity of CAN508. ACS chemical biology 20120518
Design and divergent synthesis of aza nucleosides from a chiral imino sugar. The Journal of organic chemistry 20120518
Inhibition of pyrimidine and purine nucleoside phosphorylases by a 3,5-dichlorobenzoyl-substituted 2-deoxy-D-ribose-1-phosphate derivative. Biochemical pharmacology 20120515
Toward understanding the mechanism of ion transport activity of neuronal uncoupling proteins UCP2, UCP4, and UCP5. Biochemistry 20120515
On the accessibility to conical intersections in purines: hypoxanthine and its singly protonated and deprotonated forms. Journal of the American Chemical Society 20120509
Genetic and molecular characterization reveals a unique nucleobase cation symporter 1 in Arabidopsis. FEBS letters 20120507
Total synthesis of a cyclic adenosine 5'-diphosphate ribose receptor agonist. The Journal of organic chemistry 20120504
Nonrandom distribution of cryptic repeating triplets of purines and pyrimidines (RNY)(n) in gp120 of HIV Type1. AIDS research and human retroviruses 20120501
Effects of P2Y(1) receptor antagonism on the reactivity of platelets from patients with stable coronary artery disease using aspirin and clopidogrel. British journal of pharmacology 20120501
Riboswitch structure in the ligand-free state. Wiley interdisciplinary reviews. RNA 20120501
Yield of single- and double-strand breaks and nucleobase lesions in fully hydrated plasmid DNA films irradiated with high-LET charged particles. Radiation research 20120501
Cytotoxic purine nucleoside analogues bind to A1, A2A, and A3 adenosine receptors. Naunyn-Schmiedeberg's archives of pharmacology 20120501
Initial experience with bendamustine in patients with recurrent primary central nervous system lymphoma: a case report. Journal of neuro-oncology 20120501
Development and mapping of SNP assays in allotetraploid cotton. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20120501
Differential response of Drosophila cell lines to extracellular adenosine. Insect biochemistry and molecular biology 20120501
Purine nucleosides: endogenous neuroprotectants in hypoxic brain. Journal of neurochemistry 20120501
The soluble proteome of tobacco Bright Yellow-2 cells undergoing H₂O₂-induced programmed cell death. Journal of experimental botany 20120501
Confocal Raman microspectroscopic study of folate receptor-targeted delivery of 6-mercaptopurine-embedded gold nanoparticles in a single cell. Journal of biomedical materials research. Part A 20120501
Functional analysis of the relative growth rate, chemical composition, construction and maintenance costs, and the payback time of Coffea arabica L. leaves in response to light and water availability. Journal of experimental botany 20120501
Relationships among hyperuricemia, endothelial dysfunction and cardiovascular disease: molecular mechanisms and clinical implications. Journal of cardiology 20120501
Practical considerations for conducting ecotoxicity test methods with manufactured nanomaterials: what have we learnt so far? Ecotoxicology (London, England) 20120501
Synthesis and biological evaluation of a series of thieno-expanded tricyclic purine 2'-deoxy nucleoside analogues. Bioorganic & medicinal chemistry 20120501
The adenosine deaminases of Plasmodium vivax and Plasmodium falciparum exhibit surprising differences in ligand specificity. Journal of molecular graphics & modelling 20120501
Prolonged fasting increases purine recycling in post-weaned northern elephant seals. The Journal of experimental biology 20120501
Purine biosynthesis mutants (purA and purB) of serotype 4b Listeria monocytogenes are severely attenuated for systemic infection in intragastrically inoculated A/J Mice. Foodborne pathogens and disease 20120501
Waldenström macroglobulinemia: 2012 update on diagnosis, risk stratification, and management. American journal of hematology 20120501
Untargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma brucei. PLoS neglected tropical diseases 20120501
NIBBS-search for fast and accurate prediction of phenotype-biased metabolic systems. PLoS computational biology 20120501
3-(2,4-Dichloro-phen-yl)-5-(4-fluoro-phen-yl)-2-methyl-7-(trifluoro-meth-yl)pyrazolo-[1,5-a]pyrimidine. Acta crystallographica. Section E, Structure reports online 20120501
Variability of gemcitabine accumulation and its relationship to expression of nucleoside transporters in peripheral blood mononuclear cells. Archives of pharmacal research 20120501
Treatment of hairy cell leukemia: long-term results in a developing country. Hematology (Amsterdam, Netherlands) 20120501
New and Redesigned pRS Plasmid Shuttle Vectors for Genetic Manipulation of Saccharomycescerevisiae. G3 (Bethesda, Md.) 20120501
The CanOE strategy: integrating genomic and metabolic contexts across multiple prokaryote genomes to find candidate genes for orphan enzymes. PLoS computational biology 20120501
Mechanisms of Platelet Activation and Integrin αIIβ3. Korean circulation journal 20120501
A cyclodextrin host-guest recognition approach to a label-free electrochemical DNA hybridization biosensor. The Analyst 20120421
Effect of the H-bonding on aromaticity of purine tautomers. The Journal of organic chemistry 20120420
Lower serum UA levels in Parkinson's disease patients in the Chinese population. Neuroscience letters 20120418
The formamidopyrimidines: purine lesions formed in competition with 8-oxopurines from oxidative stress. Accounts of chemical research 20120417
Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD(+). The Journal of physiology 20120415
P2Y1 purinoreceptors are fundamental to inhibitory motor control of murine colonic excitability and transit. The Journal of physiology 20120415
2-anilino-4-aryl-8H-purine derivatives as inhibitors of PDK1. Bioorganic & medicinal chemistry letters 20120415
Synthesis of novel 6-(4-substituted piperazine-1-yl)-9-(β-D-ribofuranosyl)purine derivatives, which lead to senescence-induced cell death in liver cancer cells. Journal of medicinal chemistry 20120412
Does the growth temperature of a prokaryote influence the purine content of its mRNAs? Gene 20120410
Capillary bioreactors based on human purine nucleoside phosphorylase: a new approach for ligands identification and characterization. Journal of chromatography. A 20120406
Synthesis and properties of 5-cyano-substituted nucleoside analog with a donor-donor-acceptor hydrogen-bonding pattern. The Journal of organic chemistry 20120406
New phosphate binding sites in the crystal structure of Escherichia coli purine nucleoside phosphorylase complexed with phosphate and formycin A. FEBS letters 20120405
Decreased extra-renal urate excretion is a common cause of hyperuricemia. Nature communications 20120403
Multivariate models to detect genomic signatures for a class of drugs: application to thiopurines pharmacogenomics. The pharmacogenomics journal 20120401
Mantle cell lymphoma. Critical reviews in oncology/hematology 20120401
A comparative study on mimosine, 3,4-dihydroxy pyridone (3,4-DHP) and 2,3-dihydroxy pyridone (2,3-DHP), purine derivatives (PD) excretion in the urine, thyroid hormone and blood metabolites profiles of Thai swamp buffalo (Bubalus bubalis) and Murrah buffalo (Bubalus bubalis). Tropical animal health and production 20120401
Elevated uric acid correlates with wound severity. International wound journal 20120401
A spicamycin derivative (KRN5500) provides neuropathic pain relief in patients with advanced cancer: a placebo-controlled, proof-of-concept trial. Journal of pain and symptom management 20120401
Uric acid excretion in healthy subjects: a nomogram to assess the mechanisms underlying purine metabolic disorders. Metabolism: clinical and experimental 20120401
Comparative genomics of Bifidobacterium, Lactobacillus and related probiotic genera. Microbial ecology 20120401
Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors. Molecular biology reports 20120401
CR8, a selective and potent CDK inhibitor, provides neuroprotection in experimental traumatic brain injury. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20120401
Protection of riboflavin and UVB sensitized degradation of DNA and RNA bases by natural antioxidants. Ecotoxicology and environmental safety 20120401
Domain III regulates N-type (CaV2.2) calcium channel closing kinetics. Journal of neurophysiology 20120401
Glial-derived adenosine modulates spinal motor networks in mice. Journal of neurophysiology 20120401
Primary cilia mediate mechanotransduction through control of ATP-induced Ca2+ signaling in compressed chondrocytes. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120401
Vascular endothelial function is not related to serum uric acid in healthy adults. American journal of hypertension 20120401
Transcriptome analysis of silver carp (Hypophthalmichthys molitrix) by paired-end RNA sequencing. DNA research : an international journal for rapid publication of reports on genes and genomes 20120401
Ingenuity pathways analysis of urine metabolomics phenotypes toxicity of Chuanwu in Wistar rats by UPLC-Q-TOF-HDMS coupled with pattern recognition methods. Molecular bioSystems 20120401
Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells. Molecular medicine reports 20120401
Electrochemically synthesized polymers in molecular imprinting for chemical sensing. Analytical and bioanalytical chemistry 20120401
Programmed cell death induced by high levels of cytokinin in Arabidopsis cultured cells is mediated by the cytokinin receptor CRE1/AHK4. Journal of experimental botany 20120401
Comparative modeling of HGPRT enzyme of L. donovani and binding affinities of different analogs of GMP. International journal of biological macromolecules 20120401
Unveiling Mycoplasma hyopneumoniae promoters: sequence definition and genomic distribution. DNA research : an international journal for rapid publication of reports on genes and genomes 20120401
Novel metabolic aspects related to adenosine deaminase inhibition in a human astrocytoma cell line. Neurochemistry international 20120401
The synthesis of 2'-methylseleno adenosine and guanosine 5'-triphosphates. Bioorganic & medicinal chemistry 20120401
Regulation of neutrophil function by adenosine. Arteriosclerosis, thrombosis, and vascular biology 20120401
Regulation of foam cells by adenosine. Arteriosclerosis, thrombosis, and vascular biology 20120401
Long-range heteronuclear coupling constants in 2,6-disubstituted purine derivatives. Magnetic resonance in chemistry : MRC 20120401
De novo pyrimidine nucleotide synthesis mainly occurs outside of plastids, but a previously undiscovered nucleobase importer provides substrates for the essential salvage pathway in Arabidopsis. The Plant cell 20120401
Nicotine alters the ectonucleotidases activities in lymphocytes: In vitro and in vivo studies. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120401
Leishmania induces survival, proliferation and elevated cellular dNTP levels in human monocytes promoting acceleration of HIV co-infection. PLoS pathogens 20120401
Improving treatment for patients with chronic lymphocytic leukemia. Hematology (Amsterdam, Netherlands) 20120401
Stitching together multiple data dimensions reveals interacting metabolomic and transcriptomic networks that modulate cell regulation. PLoS biology 20120401
The transcription factor AmrZ utilizes multiple DNA binding modes to recognize activator and repressor sequences of Pseudomonas aeruginosa virulence genes. PLoS pathogens 20120401
On-admission serum uric acid predicts outcomes after acute myocardial infarction: systematic review and meta-analysis of prognostic studies. Croatian medical journal 20120401
Characterisation of multiple substrate-specific (d)ITP/(d)XTPase and modelling of deaminated purine nucleotide metabolism. BMB reports 20120401
Development and validation of an improved algorithm for overlaying flexible molecules. Journal of computer-aided molecular design 20120401
A novel small molecule inhibitor of influenza A viruses that targets polymerase function and indirectly induces interferon. PLoS pathogens 20120401
Diisopropyl {[(R)-2-(2-amino-6-chloro-9H-purin-9-yl)-1-methyl-eth-oxy]meth-yl}-phospho-nate. Acta crystallographica. Section E, Structure reports online 20120401
First total synthesis of a naturally occurring iodinated 5'-deoxyxylofuranosyl marine nucleoside. Marine drugs 20120401
Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts. Oncogene 20120329
Cytochrome b mutation Y268S conferring atovaquone resistance phenotype in malaria parasite results in reduced parasite bc1 catalytic turnover and protein expression. The Journal of biological chemistry 20120323
A short story of anti-rheumatic therapy. VIII. The immunodepressants. Reumatismo 20120319
Allostery and cooperativity in Escherichia coli aspartate transcarbamoylase. Archives of biochemistry and biophysics 20120315
Role of myosin Va in purinergic vesicular neurotransmission in the gut. American journal of physiology. Gastrointestinal and liver physiology 20120315
A novel non-canonical mechanism of regulation of MST3 (mammalian Sterile20-related kinase 3). The Biochemical journal 20120315
Cell signalling by reactive lipid species: new concepts and molecular mechanisms. The Biochemical journal 20120315
HOMO energy gap dependence of hole-transfer kinetics in DNA. Journal of the American Chemical Society 20120314
Deletion of ecto-5'-nucleotidase (CD73) reveals direct action potential-dependent adenosine release. The Journal of neuroscience : the official journal of the Society for Neuroscience 20120314
Identification of novel adenosine A(2A) receptor antagonists by virtual screening. Journal of medicinal chemistry 20120308
Binding affinity prediction for ligands and receptors forming tautomers and ionization species: inhibition of mitogen-activated protein kinase-activated protein kinase 2 (MK2). Journal of medicinal chemistry 20120308
Photosensitization of DNA by β-carbolines: kinetic analysis and photoproduct characterization. Organic & biomolecular chemistry 20120307
Fumarate is cardioprotective via activation of the Nrf2 antioxidant pathway. Cell metabolism 20120307
Adenine aminohydrolase from Leishmania donovani: unique enzyme in parasite purine metabolism. The Journal of biological chemistry 20120302
Proteomic pleiotropy of OpgGH, an operon necessary for efficient growth of Salmonella enterica serovar typhimurium under low-osmotic conditions. Journal of proteome research 20120302
Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant? Journal of cardiovascular pharmacology and therapeutics 20120301
Proposed definition of 'poor mobilizer' in lymphoma and multiple myeloma: an analytic hierarchy process by ad hoc working group Gruppo ItalianoTrapianto di Midollo Osseo. Bone marrow transplantation 20120301
Simultaneous determination of metacavir and its metabolites in rat plasma using high-performance liquid chromatography with tandem mass spectrometric detection (LC-MS/MS). Biomedical chromatography : BMC 20120301
A phase I study in adults of clofarabine combined with high-dose melphalan as reduced-intensity conditioning for allogeneic transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120301
Post-remission intervention with alemtuzumab or rituximab to eradicate minimal residual disease in chronic lymphocytic leukemia: where do we stand? Leukemia & lymphoma 20120301
Folate malabsorption is associated with down-regulation of folate transporter expression and function at colon basolateral membrane in rats. The British journal of nutrition 20120301
Effects of 3 weeks GMP oral administration on glutamatergic parameters in mice neocortex. Purinergic signalling 20120301
Purine receptors and Ca(2+) signalling in the human blood-brain barrier endothelial cell line hCMEC/D3. Purinergic signalling 20120301
Wild-type and feedback-resistant phosphoribosyl pyrophosphate synthetases from Bacillus amyloliquefaciens: purification, characterization, and application to increase purine nucleoside production. Applied microbiology and biotechnology 20120301
Systematic review of purine analog treatment for chronic lymphocytic leukemia: lessons for future trials. Haematologica 20120301
Fludarabine and rituximab for relapsed or refractory hairy cell leukemia. Blood 20120301
Identification of Rv0535 as methylthioadenosine phosphorylase from Mycobacterium tuberculosis. Tuberculosis (Edinburgh, Scotland) 20120301
Plasticity of mouse enteric synapses mediated through endocannabinoid and purinergic signaling. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20120301
Back to the future: lessons learned in modern target-based and whole-cell lead optimization of antimalarials. Current topics in medicinal chemistry 20120301
The archaeal COG1901/DUF358 SPOUT-methyltransferase members, together with pseudouridine synthase Pus10, catalyze the formation of 1-methylpseudouridine at position 54 of tRNA. RNA (New York, N.Y.) 20120301
Two-step efficient synthesis of 5-methyluridine via two thermostable nucleoside phosphorylase from Aeropyrum pernix. Bioorganic & medicinal chemistry letters 20120301
Structural basis of the substrate specificity of Bacillus cereus adenosine phosphorylase. Acta crystallographica. Section D, Biological crystallography 20120301
A corrected space group for Sulfolobus sulfataricus 5'-deoxy-5'-methylthioadenosine phosphorylase II. Acta crystallographica. Section D, Biological crystallography 20120301
Dual diagnosis of dihydropyrimidine dehydrogenase deficiency and GM₁ gangliosidosis. Pediatric neurology 20120301
C6-substituted purine derivatives: an experimental and theoretical 1H, 13C and 15N NMR study. Magnetic resonance in chemistry : MRC 20120301
Feasibility of non-TBI conditioning with busulfan and fludarabine for allogeneic stem cell transplantation in lymphoid malignancy. The Korean journal of internal medicine 20120301
Quantitative Proteomics of Intracellular Campylobacter jejuni Reveals Metabolic Reprogramming. PLoS pathogens 20120301
The impact of oxygen on metabolic evolution: a chemoinformatic investigation. PLoS computational biology 20120301
Aspartate aminotransferase: bridging carbohydrate and energy metabolism in Plasmodium falciparum. Current drug metabolism 20120301
Broad-specificity mRNA-rRNA complementarity in efficient protein translation. PLoS genetics 20120301
Anti-obesity and anti-diabetic effects of Yerba Mate (Ilex paraguariensis) in C57BL/6J mice fed a high-fat diet. Laboratory animal research 20120301
[Measurement of purines and uric acid simultaneous in meat with high performance liquid chromatographys]. Wei sheng yan jiu = Journal of hygiene research 20120301
Initiation of 8-oxoguanine base excision repair within trinucleotide tandem repeats. Biochemistry. Biokhimiia 20120301
Probing transient Hoogsteen hydrogen bonds in canonical duplex DNA using NMR relaxation dispersion and single-atom substitution. Journal of the American Chemical Society 20120227
Allopurinol acutely increases adenosine triphospate energy delivery in failing human hearts. Journal of the American College of Cardiology 20120227
A p53-inducible microRNA-34a downregulates Ras signaling by targeting IMPDH. Biochemical and biophysical research communications 20120224
Synthesis and biological activity of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl regioisomers as inhibitors of de novo purine biosynthesis with selectivity for cellular uptake by high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier. Journal of medicinal chemistry 20120223
Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A. Journal of medicinal chemistry 20120223
Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells. Journal of medicinal chemistry 20120223
N-phosphonocarbonylpyrrolidine derivatives of guanine: a new class of bi-substrate inhibitors of human purine nucleoside phosphorylase. Journal of medicinal chemistry 20120223
The influence of homocysteine and oxidative stress on pregnancy outcome. Journal of medicine and life 20120222
Selection of monoclonal antibodies against 6-oxo-M(1)dG and their use in an LC-MS/MS assay for the presence of 6-oxo-M(1)dG in vivo. Chemical research in toxicology 20120220
Structures of (5'S)-8,5'-Cyclo-2'-deoxyguanosine Mismatched with dA or dT. Chemical research in toxicology 20120220
Proteomic analysis of hemoglobin H-constant spring (Hb H-CS) erythroblasts. Blood cells, molecules & diseases 20120215
Base pairing at the abasic site in DNA duplexes and its application in adenosine aptasensors. Chembiochem : a European journal of chemical biology 20120213
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID. Blood 20120209
Change in tea polyphenol and purine alkaloid composition during solid-state fungal fermentation of postfermented tea. Journal of agricultural and food chemistry 20120208
Platinum-modified adenines: unprecedented protonation behavior revealed by NMR spectroscopy and relativistic density-functional theory calculations. Inorganic chemistry 20120206
Proteome of the early embryo-maternal dialogue in the cattle uterus. Journal of proteome research 20120203
Vitamin C deficiency activates the purine nucleotide cycle in zebrafish. The Journal of biological chemistry 20120203
Proton transfers along hydrogen bonds in the tautomerization of purine. The journal of physical chemistry. A 20120202
Recent advances in renal urate transport: characterization of candidate transporters indicated by genome-wide association studies. Clinical and experimental nephrology 20120201
Primary immunodeficiency diseases associated with neurologic manifestations. Journal of clinical immunology 20120201
MicroRNA-mediated dysregulation of neural developmental genes in HPRT deficiency: clues for Lesch-Nyhan disease? Human molecular genetics 20120201
DNA glycosylases: in DNA repair and beyond. Chromosoma 20120201
Partial adenosine A1 receptor agonists for cardiovascular therapies. Purinergic signalling 20120201
Gene expression profile in response to doxorubicin-rapamycin combined treatment of HER-2-overexpressing human mammary epithelial cell lines. Molecular cancer therapeutics 20120201
Using antibodies against P2Y and P2X receptors in purinergic signaling research. Purinergic signalling 20120201
Roscovitine inhibits CaV3.1 (T-type) channels by preferentially affecting closed-state inactivation. The Journal of pharmacology and experimental therapeutics 20120201
Measurement of purine release with microelectrode biosensors. Purinergic signalling 20120201
Inhibitors of membranous adenylyl cyclases. Trends in pharmacological sciences 20120201
The crystal structure of Leishmania major N(5),N(10)-methylenetetrahydrofolate dehydrogenase/cyclohydrolase and assessment of a potential drug target. Molecular and biochemical parasitology 20120201
Biomass production of site selective 13C/15N nucleotides using wild type and a transketolase E. coli mutant for labeling RNA for high resolution NMR. Journal of biomolecular NMR 20120201
Training-induced adaptation in purine metabolism in high-level sprinters vs. triathletes. Journal of applied physiology (Bethesda, Md. : 1985) 20120201
A continuous spectrophotometric assay for mitogen-activated protein kinase kinases. Analytical biochemistry 20120201
Natural product DNA major groove binders. Natural product reports 20120201
Synthesis of purine N9-[2-hydroxy-3-O-(phosphonomethoxy)propyl] derivatives and their side-chain modified analogs as potential antimalarial agents. Bioorganic & medicinal chemistry 20120201
Serum adenosine deaminase activity as a predictor of disease severity in ulcerative colitis. Journal of Crohn's & colitis 20120201
Construction and completion of flux balance models from pathway databases. Bioinformatics (Oxford, England) 20120201
Is bendamustine an ideal partner for rituximab in the management of relapsed chronic lymphocytic leukemia? Results of a multicenter Phase II trial. Expert review of hematology 20120201
Simultaneous determination of polyphenols and major purine alkaloids in Greek Sideritis species, herbal extracts, green tea, black tea, and coffee by high-performance liquid chromatography-diode array detection. Journal of separation science 20120201
Positive evolutionary selection of an HD motif on Alzheimer precursor protein orthologues suggests a functional role. PLoS computational biology 20120201
Ethyl 1-(2-hy-droxy-eth-yl)-2-(4-meth-oxy-phen-yl)-1H-benzimidazole-5-carboxyl-ate monohydrate. Acta crystallographica. Section E, Structure reports online 20120201
Folate depletion changes gene expression of fatty acid metabolism, DNA synthesis, and circadian cycle in male mice. Nutrition research (New York, N.Y.) 20120201
Polymorphisms in 1-carbon metabolism, epigenetics and folate-related pathologies. Journal of nutrigenetics and nutrigenomics 20120201
Dynamic energy landscapes of riboswitches help interpret conformational rearrangements and function. PLoS computational biology 20120201
Clear genetic distinctiveness between human- and pig-derived Trichuris based on analyses of mitochondrial datasets. PLoS neglected tropical diseases 20120201
Comparison of insertional RNA editing in Myxomycetes. PLoS computational biology 20120201
Clinical features and long term outcome of 102 treated autoimmune hepatitis patients. Hepatitis monthly 20120201
[Hepatotoxicity of perfluorooctanoic acid in human hepatocytes using metabonomics]. Se pu = Chinese journal of chromatography 20120201
Synthesis of N-(2-chloro purin-6-yl) aza-18-crown-6 and its interaction with human serum albumin. Organic & biomolecular chemistry 20120128
Cytotoxic and genotoxic effects of silver nanoparticles in testicular cells. Toxicology 20120127
Genotype-phenotype correlations in Lesch-Nyhan disease: moving beyond the gene. The Journal of biological chemistry 20120127
Analysis of Camellia sinensis green and black teas via ultra high performance liquid chromatography assisted by liquid-liquid partition and two-dimensional liquid chromatography (size exclusion × reversed phase). Journal of chromatography. A 20120127
Reactivity of the antitumor complex (H2trz)[trans-RuCl4(N2-Htrz)2] in the presence of DNA purines within a fluorinated silica matrix. The journal of physical chemistry. B 20120126
Structural studies of intermediates along the cyclization pathway of Aplysia ADP-ribosyl cyclase. Journal of molecular biology 20120120
Cadmium influences the 5-Fluorouracil cytotoxic effects on breast cancer cells. European journal of histochemistry : EJH 20120120
Tumour suppressors miR-1 and miR-133a target the oncogenic function of purine nucleoside phosphorylase (PNP) in prostate cancer. British journal of cancer 20120117
Core promoter STRs: novel mechanism for inter-individual variation in gene expression in humans. Gene 20120115
Electrochemical oxidation of purine and pyrimidine bases based on the boron-doped nanotubes modified electrode. Biosensors & bioelectronics 20120115
Synthesis of 9-phosphonoalkyl and 9-phosphonoalkoxyalkyl purines: evaluation of their ability to act as inhibitors of Plasmodium falciparum, Plasmodium vivax and human hypoxanthine-guanine-(xanthine) phosphoribosyltransferases. Bioorganic & medicinal chemistry 20120115
NMR analysis of the rat neurochemical changes induced by middle cerebral artery occlusion. Talanta 20120115
Label-free fluorescence detection of the depurination activity of ribosome inactivating protein toxins. Chemical communications (Cambridge, England) 20120114
Low-energy electron scattering with the purine bases of DNA/RNA using the R-matrix method. The Journal of chemical physics 20120114
Thymine dimer photoreversal in purine-containing trinucleotides. The journal of physical chemistry. B 20120112
Formamide-based prebiotic synthesis of nucleobases: a kinetically accessible reaction route. The journal of physical chemistry. A 20120112
Searching for DNA lesions: structural evidence for lower- and higher-affinity DNA binding conformations of human alkyladenine DNA glycosylase. Biochemistry 20120110
Simple genetic diagnosis of hairy cell leukemia by sensitive detection of the BRAF-V600E mutation. Blood 20120105
Divergence and convergence in enzyme evolution. The Journal of biological chemistry 20120102
Site-specific control of N7-metal coordination in DNA by a fluorescent purine derivative. Chemistry (Weinheim an der Bergstrasse, Germany) 20120102
Hepatosplenic gamma-delta T-cell lymphoma in a female patient after delivery. Hematology reports 20120102
Magnetic resonance imaging of the brain in adenylosuccinate lyase deficiency: a report of seven cases and a review of the literature. European journal of pediatrics 20120101
Cell tracking in cardiac repair: what to image and how to image. European radiology 20120101
Benzene metabolite 1,2,4-benzenetriol induces halogenated DNA and tyrosines representing halogenative stress in the HL-60 human myeloid cell line. Environmental health perspectives 20120101
Characterization of biofumigated Ralstonia solanacearum cells using micro-Raman spectroscopy and electron microscopy. Phytopathology 20120101
Alterations in vasoconstrictor responses to the endothelium-derived contracting factor uridine adenosine tetraphosphate are region specific in DOCA-salt hypertensive rats. Pharmacological research 20120101
Role of ARABIDOPSIS A-FIFTEEN in regulating leaf senescence involves response to reactive oxygen species and is dependent on ETHYLENE INSENSITIVE2. Journal of experimental botany 20120101
Inhibition of the adenylyl cyclase toxin, edema factor, from Bacillus anthracis by a series of 18 mono- and bis-(M)ANT-substituted nucleoside 5'-triphosphates. Naunyn-Schmiedeberg's archives of pharmacology 20120101
Dietary oxidative stress and antioxidant defense with an emphasis on plant extract administration. Cell stress & chaperones 20120101
DNA-Platinum Thin Films for Use in Chemoradiation Therapy Studies. Bioinorganic chemistry and applications 20120101
Adenosine and immune imbalance in visceral leishmaniasis: the possible role of ectonucleotidases. Journal of tropical medicine 20120101
Antilipogenic and anti-inflammatory activities of Codonopsis lanceolata in mice hepatic tissues after chronic ethanol feeding. Journal of biomedicine & biotechnology 20120101
Crystal structure and molecular dynamics studies of purine nucleoside phosphorylase from Mycobacterium tuberculosis associated with acyclovir. Biochimie 20120101
Purinergic P2X3 heteroreceptors enhance parasympathetic motor drive in isolated porcine detrusor, a reliable model for development of P2X selective blockers for detrusor hyperactivity. Pharmacological research 20120101
Patterns of interaction between genetic and nongenetic attributes and methotrexate efficacy in rheumatoid arthritis. Pharmacogenetics and genomics 20120101
Reduction of the 'burst release' of copper ions from copper-based intrauterine devices by organic inhibitors. Contraception 20120101
An update on the pathology and clinical management of gouty arthritis. Clinical rheumatology 20120101
Fruit and vegetable and fried food consumption and 3-(2-deoxy-β-D-erythro-pentafuranosyl)pyrimido[1,2-α] purin-10(3H)-one deoxyguanosine adduct formation. Free radical research 20120101
Asymmetry of 13C labeled 3-pyruvate affords improved site specific labeling of RNA for NMR spectroscopy. Journal of biomolecular NMR 20120101
Identification of agents that reduce renal hypoxia-reoxygenation injury using cell-based screening: purine nucleosides are alternative energy sources in LLC-PK1 cells during hypoxia. Archives of biochemistry and biophysics 20120101
Synthesis and evaluation of the substrate activity of C-6 substituted purine ribosides with E. coli purine nucleoside phosphorylase: palladium mediated cross-coupling of organozinc halides with 6-chloropurine nucleosides. European journal of medicinal chemistry 20120101
Applicability of a sensitive duplex real-time PCR assay for identifying B/Yamagata and B/Victoria lineages of influenza virus from clinical specimens. Applied microbiology and biotechnology 20120101
Adenosine augments IL-10 production by microglial cells through an A2B adenosine receptor-mediated process. Journal of immunology (Baltimore, Md. : 1950) 20120101
Structure-based design of PDK1 inhibitors. Bioorganic & medicinal chemistry letters 20120101
Temozolomide: mechanisms of action, repair and resistance. Current molecular pharmacology 20120101
Use of cyclosporine in uterine transplantation. Journal of transplantation 20120101
Physiology, biochemistry and possible applications of microbial caffeine degradation. Applied microbiology and biotechnology 20120101
Treatment of relapsed or refractory chronic lymphocytic leukemia. Cancer control : journal of the Moffitt Cancer Center 20120101
Dissecting the role of glutathione biosynthesis in Plasmodium falciparum. Molecular microbiology 20120101
Monitoring metabolites consumption and secretion in cultured cells using ultra-performance liquid chromatography quadrupole-time of flight mass spectrometry (UPLC-Q-ToF-MS). Analytical and bioanalytical chemistry 20120101
Recent advances in CSF biomarkers for Parkinson's disease. Parkinsonism & related disorders 20120101
The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes. Journal of oncology 20120101
Uric acid, hyperuricemia and vascular diseases. Frontiers in bioscience (Landmark edition) 20120101
Oxidative Stress and Down Syndrome: A Route toward Alzheimer-Like Dementia. Current gerontology and geriatrics research 20120101
Metal-mediated base pairs in nucleic acids with purine- and pyrimidine-derived nucleosides. Metal ions in life sciences 20120101
Proteomic analysis on acetate metabolism in Citrobacter sp. BL-4. International journal of biological sciences 20120101
My treatment approach to hairy cell leukemia. Mayo Clinic proceedings 20120101
On the molecular mechanism of GC content variation among eubacterial genomes. Biology direct 20120101
Uric acid is an independent risk factor for carotid atherosclerosis in a Japanese elderly population without metabolic syndrome. Cardiovascular diabetology 20120101
Alternative splicing of RNA triplets is often regulated and accelerates proteome evolution. PLoS biology 20120101
Down-regulation of myogenin can reverse terminal muscle cell differentiation. PloS one 20120101
Genomic characterization of the Taylorella genus. PloS one 20120101
Lipopolysaccharide priming enhances expression of effectors of immune defence while decreasing expression of pro-inflammatory cytokines in mammary epithelia cells from cows. BMC genomics 20120101
Interactions between prostaglandins, leukotrienes and HIV-1: possible implications for the central nervous system. Retrovirology 20120101
Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair. Cell death & disease 20120101
TLR9 agonist protects mice from radiation-induced gastrointestinal syndrome. PloS one 20120101
Customisation of the exome data analysis pipeline using a combinatorial approach. PloS one 20120101
Blue news update: BODIPY-GTP binds to the blue-light receptor YtvA while GTP does not. PloS one 20120101
The architecture and ppGpp-dependent expression of the primary transcriptome of Salmonella Typhimurium during invasion gene expression. BMC genomics 20120101
Integration of gene-based markers in a pearl millet genetic map for identification of candidate genes underlying drought tolerance quantitative trait loci. BMC plant biology 20120101
Modulation of miRNA expression by dietary polyphenols in apoE deficient mice: a new mechanism of the action of polyphenols. PloS one 20120101
Transcriptional ontogeny of the developing liver. BMC genomics 20120101
Effects of adenosine A₂A receptor activation and alanyl-glutamine in Clostridium difficile toxin-induced ileitis in rabbits and cecitis in mice. BMC infectious diseases 20120101
Nucleotide and phylogenetic analyses of the Chlamydia trachomatis ompA gene indicates it is a hotspot for mutation. BMC research notes 20120101
SWI/SNF-mediated chromatin remodeling induces Z-DNA formation on a nucleosome. Cell & bioscience 20120101
Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds. BMC developmental biology 20120101
Erythrocyte inosine triphosphatase activity is decreased in HIV-seropositive individuals. PloS one 20120101
5-Fluorouracil-loaded poly(ε-caprolactone) nanoparticles combined with phage E gene therapy as a new strategy against colon cancer. International journal of nanomedicine 20120101
Structure of S. aureus HPPK and the discovery of a new substrate site inhibitor. PloS one 20120101
Cyclin-dependent kinase 9 activity regulates neutrophil spontaneous apoptosis. PloS one 20120101
Endothelial progenitor cells (EPCs) as gene carrier system for rat model of human glioma. PloS one 20120101
Sequence coevolution between RNA and protein characterized by mutual information between residue triplets. PloS one 20120101
HCMV targets the metabolic stress response through activation of AMPK whose activity is important for viral replication. PLoS pathogens 20120101
Identification of novel candidate oncogenes in chromosome region 17p11.2-p12 in human osteosarcoma. PloS one 20120101
Efficacy of combined therapy with amantadine, oseltamivir, and ribavirin in vivo against susceptible and amantadine-resistant influenza A viruses. PloS one 20120101
High-resolution melting analysis as a powerful tool to discriminate and genotype Pseudomonas savastanoi pathovars and strains. PloS one 20120101
The ζ toxin induces a set of protective responses and dormancy. PloS one 20120101
A distinct metabolic signature predicts development of fasting plasma glucose. Journal of clinical bioinformatics 20120101
Catalog of microRNA seed polymorphisms in vertebrates. PloS one 20120101
Novel, objective, multivariate biomarkers composed of plasma amino acid profiles for the diagnosis and assessment of inflammatory bowel disease. PloS one 20120101
microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers. Oncotarget 20120101
Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. BMC genomics 20120101
Significance of dietary antioxidants for health. International journal of molecular sciences 20120101
Astroglial excitability and gliotransmission: an appraisal of Ca2+ as a signalling route. ASN neuro 20120101
African American patients with gout: efficacy and safety of febuxostat vs allopurinol. BMC musculoskeletal disorders 20120101
Genome sequence of Desulfitobacterium hafniense DCB-2, a Gram-positive anaerobe capable of dehalogenation and metal reduction. BMC microbiology 20120101
Deglutitive inhibition, latency between swallow and esophageal contractions and primary esophageal motor disorders. Journal of neurogastroenterology and motility 20120101
Emerging pharmacotherapies for adult patients with acute lymphoblastic leukemia. Clinical Medicine Insights. Oncology 20120101
Toward a Systemic Understanding of Listeria monocytogenes Metabolism during Infection. Frontiers in microbiology 20120101
Independent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic region. PloS one 20120101
Inhibitors of the cellular trafficking of ricin. Toxins 20120101
Chemical approaches for structure and function of RNA in postgenomic era. Journal of nucleic acids 20120101
Extra-renal elimination of uric acid via intestinal efflux transporter BCRP/ABCG2. PloS one 20120101
Proteome adaptation to high temperatures in the ectothermic hydrothermal vent Pompeii worm. PloS one 20120101
Regulation of the let-7a-3 promoter by NF-κB. PloS one 20120101
Blood-based gene expression profiles models for classification of subsyndromal symptomatic depression and major depressive disorder. PloS one 20120101
A Francisella tularensis live vaccine strain that improves stimulation of antigen-presenting cells does not enhance vaccine efficacy. PloS one 20120101
Transcriptome analyses of a salt-tolerant cytokinin-deficient mutant reveal differential regulation of salt stress response by cytokinin deficiency. PloS one 20120101
Analysis of the genome of the sexually transmitted insect virus Helicoverpa zea nudivirus 2. Viruses 20120101
The interplay of mutations and electronic properties in disease-related genes. Scientific reports 20120101
Protein-based identification of quantitative trait loci associated with malignant transformation in two HER2+ cellular models of breast cancer. Proteome science 20120101
Genome-wide maps of circulating miRNA biomarkers for ulcerative colitis. PloS one 20120101
The pyrimidine nucleotide biosynthetic pathway modulates production of biofilm determinants in Escherichia coli. PloS one 20120101
The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation. PloS one 20120101
A measure of the promiscuity of proteins and characteristics of residues in the vicinity of the catalytic site that regulate promiscuity. PloS one 20120101
A novel protein kinase-like domain in a selenoprotein, widespread in the tree of life. PloS one 20120101
Targeted expression of Cre recombinase provokes placental-specific DNA recombination in transgenic mice. PloS one 20120101
Identification of new splice sites used for generation of rev transcripts in human immunodeficiency virus type 1 subtype C primary isolates. PloS one 20120101
LAL regulators SCO0877 and SCO7173 as pleiotropic modulators of phosphate starvation response and actinorhodin biosynthesis in Streptomyces coelicolor. PloS one 20120101
New insight into the transcarbamylase family: the structure of putrescine transcarbamylase, a key catalyst for fermentative utilization of agmatine. PloS one 20120101
Neuromyelitis optica: an antibody-mediated disorder of the central nervous system. Neurology research international 20120101
Protective effect of Emilia sonchifolia (L.) against high protein diet induced oxidative stress in pancreas of Wistar rats. Journal of pharmacy & bioallied sciences 20120101
Two sides of the Myc-induced DNA damage response: from tumor suppression to tumor maintenance. Cell division 20120101
Analysis of intracellular expressed proteins of Mycobacterium tuberculosis clinical isolates. Proteome science 20120101
Genetic polymorphisms of the TYMS gene are not associated with congenital cardiac septal defects in a Han Chinese population. PloS one 20120101
Global transcriptome profiling of the pine shoot beetle, Tomicus yunnanensis (Coleoptera: Scolytinae). PloS one 20120101
Pivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells. PloS one 20120101
Genome-wide analysis of the emerging infection with Mycobacterium avium subspecies paratuberculosis in the Arabian camels (Camelus dromedarius). PloS one 20120101
Flavonoid glycosides isolated from unique legume plant extracts as novel inhibitors of xanthine oxidase. PloS one 20120101
Comparative genomics and transcriptional profiles of Saccharopolyspora erythraea NRRL 2338 and a classically improved erythromycin over-producing strain. Microbial cell factories 20120101
New antiviral agents for hepatitis C. F1000 biology reports 20120101
ArgR of Streptomyces coelicolor is a versatile regulator. PloS one 20120101
Sirtuins as regulators of the yeast metabolic network. Frontiers in pharmacology 20120101
Safety and efficacy of pemetrexed in maintenance therapy of non-small cell lung cancer. Clinical Medicine Insights. Oncology 20120101
Identification of DreI as an antiviral factor regulated by RLR signaling pathway. PloS one 20120101
Transcriptomics comparison between porcine adipose and bone marrow mesenchymal stem cells during in vitro osteogenic and adipogenic differentiation. PloS one 20120101
Detailed mitochondrial phenotyping by high resolution metabolomics. PloS one 20120101
Is Friedreich ataxia an epigenetic disorder? Clinical epigenetics 20120101
Insight into trichomonas vaginalis genome evolution through metabolic pathways comparison. Bioinformation 20120101
Extracellular ATP triggers proteolysis and cytosolic Ca²⁺ rise in Plasmodium berghei and Plasmodium yoelii malaria parasites. Malaria journal 20120101
Role of the gerA operon in L-alanine germination of Bacillus licheniformis spores. BMC microbiology 20120101
A low protein diet during pregnancy provokes a lasting shift of hepatic expression of genes related to cell cycle throughout ontogenesis in a porcine model. BMC genomics 20120101
Leukotrienes inhibit early stages of HIV-1 infection in monocyte-derived microglia-like cells. Journal of neuroinflammation 20120101
Expression of Tas1 taste receptors in mammalian spermatozoa: functional role of Tas1r1 in regulating basal Ca²⁺ and cAMP concentrations in spermatozoa. PloS one 20120101
Divergent roles of Salmonella pathogenicity island 2 and metabolic traits during interaction of S. enterica serovar typhimurium with host cells. PloS one 20120101
Common changes in global gene expression induced by RNA polymerase inhibitors in Shigella flexneri. PloS one 20120101
Pulmonary langerhans cell histiocytosis. Orphanet journal of rare diseases 20120101
Disinfection of ocular cells and tissues by atmospheric-pressure cold plasma. PloS one 20120101
Genome stability of Lyme disease spirochetes: comparative genomics of Borrelia burgdorferi plasmids. PloS one 20120101
NF-κB as potential target in the treatment of melanoma. Journal of translational medicine 20120101
Codon Deviation Coefficient: a novel measure for estimating codon usage bias and its statistical significance. BMC bioinformatics 20120101
Quantitative proteome profiling of C. burnetii under tetracycline stress conditions. PloS one 20120101
A deadenylase assay by size-exclusion chromatography. PloS one 20120101
Transcriptome profiling of testis during sexual maturation stages in Eriocheir sinensis using Illumina sequencing. PloS one 20120101
[Purine in common plant food in China]. Wei sheng yan jiu = Journal of hygiene research 20120101
Transcriptional profiling of ESTs from the biocontrol fungus Chaetomium cupreum. TheScientificWorldJournal 20120101
Oxidative stress level in the testes of mice and rats during nickel intoxication. TheScientificWorldJournal 20120101
Understanding communication signals during mycobacterial latency through predicted genome-wide protein interactions and boolean modeling. PloS one 20120101
Different inhibitory potency of febuxostat towards mammalian and bacterial xanthine oxidoreductases: insight from molecular dynamics. Scientific reports 20120101
Perturbation of cytokinin and ethylene-signalling pathways explain the strong rooting phenotype exhibited by Arabidopsis expressing the Schizosaccharomyces pombe mitotic inducer, cdc25. BMC plant biology 20120101
Dietary habits in women with recurrent idiopathic calcium nephrolithiasis. Journal of translational medicine 20120101
Management of cutaneous T cell lymphoma: new and emerging targets and treatment options. Cancer management and research 20120101
Regular Multivitamin Supplement Use, Single Nucleotide Polymorphisms in ATIC, SHMT2, and SLC46A1, and Risk of Ovarian Carcinoma. Frontiers in genetics 20120101
The use of mouse models for understanding the biology of down syndrome and aging. Current gerontology and geriatrics research 20120101
The evolution of methotrexate as a treatment for ectopic pregnancy and gestational trophoblastic neoplasia: a review. ISRN obstetrics and gynecology 20120101
Comparison of the effects of adenosine, inosine, and their combination as an adjunct to reperfusion in the treatment of acute myocardial infarction. ISRN cardiology 20120101
Comparative proteomic analysis of early salt stress-responsive proteins in roots of SnRK2 transgenic rice. Proteome science 20120101
Cellular Links between Neuronal Activity and Energy Homeostasis. Frontiers in pharmacology 20120101
Characterization of an Nmr homolog that modulates GATA factor-mediated nitrogen metabolite repression in Cryptococcus neoformans. PloS one 20120101
Genome sequence and transcriptome analysis of the radioresistant bacterium Deinococcus gobiensis: insights into the extreme environmental adaptations. PloS one 20120101
State-of-the-Art Management of Patients Suffering from Chronic Lymphocytic Leukemia. Clinical Medicine Insights. Oncology 20120101
From murine to human nude/SCID: the thymus, T-cell development and the missing link. Clinical & developmental immunology 20120101
Tissue distribution and metabolism of guanosine in rats following intraperitoneal injection. Journal of biological regulators and homeostatic agents 20120101
High plasma uric acid concentration: causes and consequences. Diabetology & metabolic syndrome 20120101
Identification of novel Mt-Guab2 inhibitor series active against M. tuberculosis. PloS one 20120101
Identification of chromosomal genes in Yersinia pestis that influence type III secretion and delivery of Yops into target cells. PloS one 20120101
Temporal patterns of nucleotide misincorporations and DNA fragmentation in ancient DNA. PloS one 20120101
Comparative analysis of gene content evolution in phytoplasmas and mycoplasmas. PloS one 20120101
The complete mitochondrial genome of the small yellow croaker and partitioned Bayesian analysis of Sciaenidae fish phylogeny. Genetics and molecular biology 20120101
Astragalin from Cassia alata induces DNA adducts in vitro and repairable DNA damage in the yeast Saccharomyces cerevisiae. International journal of molecular sciences 20120101
Metabonomic profiles delineate the effect of traditional Chinese medicine sini decoction on myocardial infarction in rats. PloS one 20120101
Universal sequence replication, reversible polymerization and early functional biopolymers: a model for the initiation of prebiotic sequence evolution. PloS one 20120101
Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes. BMC genomics 20120101
A gestational high protein diet affects the abundance of muscle transcripts related to cell cycle regulation throughout development in porcine progeny. PloS one 20120101
Genome-wide association analysis of oxidative stress resistance in Drosophila melanogaster. PloS one 20120101
A family-wide RT-PCR assay for detection of paramyxoviruses and application to a large-scale surveillance study. PloS one 20120101
Selection of suitable reference genes for RT-qPCR analyses in cyanobacteria. PloS one 20120101
Channel-forming activities in the glycosomal fraction from the bloodstream form of Trypanosoma brucei. PloS one 20120101
The Chlamydia psittaci genome: a comparative analysis of intracellular pathogens. PloS one 20120101
Complexity of the Mycoplasma fermentans M64 genome and metabolic essentiality and diversity among mycoplasmas. PloS one 20120101
Assessment of the red cell proteome of young patients with unexplained hemolytic anemia by two-dimensional differential in-gel electrophoresis (DIGE). PloS one 20120101
Chronic inflammatory diseases are stimulated by current lifestyle: how diet, stress levels and medication prevent our body from recovering. Nutrition & metabolism 20120101
Resident cardiac immune cells and expression of the ectonucleotidase enzymes CD39 and CD73 after ischemic injury. PloS one 20120101
Altered calcium signaling following traumatic brain injury. Frontiers in pharmacology 20120101
The HSP90 inhibitor NVP-AUY922 radiosensitizes by abrogation of homologous recombination resulting in mitotic entry with unresolved DNA damage. PloS one 20120101
Multicenter uric acid biosensor based on tetrapod-shaped ZnO nanostructures. Journal of nanoscience and nanotechnology 20120101
Endocannabinoid-dopamine interactions in striatal synaptic plasticity. Frontiers in pharmacology 20120101
Insights into the mechanism of bovine CD38/NAD+glycohydrolase from the X-ray structures of its Michaelis complex and covalently-trapped intermediates. PloS one 20120101
The role of methylation in the intrinsic dynamics of B- and Z-DNA. PloS one 20120101
The role of cytokines and inflammatory cells in perinatal brain injury. Neurology research international 20120101
MiR-133b targets antiapoptotic genes and enhances death receptor-induced apoptosis. PloS one 20120101
Update on treatment of follicular non-Hodgkin's lymphoma: focus on potential of bortezomib. Patient preference and adherence 20120101
Alternative Mechanisms to Initiate Translation in Eukaryotic mRNAs. Comparative and functional genomics 20120101
Novel therapies for aggressive B-cell lymphoma. Advances in hematology 20120101
Network-based gene expression biomarkers for cold and heat patterns of rheumatoid arthritis in traditional chinese medicine. Evidence-based complementary and alternative medicine : eCAM 20120101
Proteomics characterization of cytoplasmic and lipid-associated membrane proteins of human pathogen Mycoplasma fermentans M64. PloS one 20120101
Does Branched-Chain Amino Acids Supplementation Modulate Skeletal Muscle Remodeling through Inflammation Modulation? Possible Mechanisms of Action. Journal of nutrition and metabolism 20120101
Maximum expected accuracy structural neighbors of an RNA secondary structure. BMC bioinformatics 20120101
Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity. ASN neuro 20120101
[The characteristics of metabolism in patients with fractures of shin and thigh bones depending on immobilization period]. Klinicheskaia laboratornaia diagnostika 20120101
Bioguided Fractionation Shows Cassia alata Extract to Inhibit Staphylococcus epidermidis and Pseudomonas aeruginosa Growth and Biofilm Formation. Evidence-based complementary and alternative medicine : eCAM 20120101
Current view on phytoplasma genomes and encoded metabolism. TheScientificWorldJournal 20120101
An unanticipated difficult airway in Lesch-Nyhan syndrome. Journal of anaesthesiology, clinical pharmacology 20120101
Metabolomic applications to decipher gut microbial metabolic influence in health and disease. Frontiers in physiology 20120101
Reduced neurobehavioral impairment from sleep deprivation in older adults: contribution of adenosinergic mechanisms. Frontiers in neurology 20120101
Protection of rat cardiac myocytes by fructose-1,6-bisphosphate and 2,3-butanedione. PloS one 20120101
Deletion of Dicer in smooth muscle affects voiding pattern and reduces detrusor contractility and neuroeffector transmission. PloS one 20120101
CRISPR interference directs strand specific spacer acquisition. PloS one 20120101
Generation and analysis of a mouse intestinal metatranscriptome through Illumina based RNA-sequencing. PloS one 20120101
Novel ATP-independent RNA annealing activity of the dengue virus NS3 helicase. PloS one 20120101
Ammonia oxidizing bacteria community dynamics in a pilot-scale wastewater treatment plant. PloS one 20120101
Astrocyte-specific disruption of SynCAM1 signaling results in ADHD-like behavioral manifestations. PloS one 20120101
Plasma adenosine deaminase isoform 2 in cancer patients undergoing chemotherapy. British journal of biomedical science 20120101
Fibroblasts from phenotypically normal palmar fascia exhibit molecular profiles highly similar to fibroblasts from active disease in Dupuytren's Contracture. BMC medical genomics 20120101
SIRT2 as a Therapeutic Target for Age-Related Disorders. Frontiers in pharmacology 20120101
The dopamine D2 receptor gene in lamprey, its expression in the striatum and cellular effects of D2 receptor activation. PloS one 20120101
IspE inhibitors identified by a combination of in silico and in vitro high-throughput screening. PloS one 20120101
Pokeweed antiviral protein increases HIV-1 particle infectivity by activating the cellular mitogen activated protein kinase pathway. PloS one 20120101
The influence of autonomic dysfunction associated with aging and type 2 diabetes on daily life activities. Experimental diabetes research 20120101
Riboflavin ameliorates cisplatin induced toxicities under photoillumination. PloS one 20120101
Comparison of adenosine deaminase levels in serum and synovial fluid between patients with rheumatoid arthritis and osteoarthritis. International journal of clinical and experimental medicine 20120101
Time dependent neuroprotection of mycophenolate mofetil: effects on temporal dynamics in glial proliferation, apoptosis, and scar formation. Journal of neuroinflammation 20120101
The fbpA/sapM double knock out strain of Mycobacterium tuberculosis is highly attenuated and immunogenic in macrophages. PloS one 20120101
Efficacy and safety of low-dose everolimus as maintenance immunosuppression in cardiac transplant recipients. Journal of transplantation 20120101
Dynamic metabolomics differentiates between carbon and energy starvation in recombinant Saccharomyces cerevisiae fermenting xylose. Biotechnology for biofuels 20120101
Mycobacterium tuberculosis and Clostridium difficille interactomes: demonstration of rapid development of computational system for bacterial interactome prediction. Microbial informatics and experimentation 20120101
Constitutive and treatment-induced CXCL8-signalling selectively modulates the efficacy of anti-metabolite therapeutics in metastatic prostate cancer. PloS one 20120101
Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Current pharmaceutical design 20120101
Regulation of Translation Initiation under Abiotic Stress Conditions in Plants: Is It a Conserved or Not so Conserved Process among Eukaryotes? Comparative and functional genomics 20120101
New insights in staging and chemotherapy of African trypanosomiasis and possible contribution of medicinal plants. TheScientificWorldJournal 20120101
Identification of novel potential β-N-acetyl-D-hexosaminidase inhibitors by virtual screening, molecular dynamics simulation and MM-PBSA calculations. International journal of molecular sciences 20120101
Study of drug metabolism by xanthine oxidase. International journal of molecular sciences 20120101
High nutrient transport and cycling potential revealed in the microbial metagenome of Australian sea lion (Neophoca cinerea) faeces. PloS one 20120101
Differential actions of chlorhexidine on the cell wall of Bacillus subtilis and Escherichia coli. PloS one 20120101
Urate and its transgenic depletion modulate neuronal vulnerability in a cellular model of Parkinson's disease. PloS one 20120101
Percutaneous holmium laser fulguration of calyceal diverticula. Case reports in urology 20120101
Comparative genome analysis of central nitrogen metabolism and its control by GlnR in the class Bacilli. BMC genomics 20120101
Electrospray ionization mass spectrometry: a technique to access the information beyond the molecular weight of the analyte. International journal of analytical chemistry 20120101
Transcriptome characterization by RNA-seq unravels the mechanisms of butyrate-induced epigenomic regulation in bovine cells. PloS one 20120101
Uric acid is more strongly associated with impaired glucose regulation in women than in men from the general population: the KORA F4-Study. PloS one 20120101
SUMOylation of paraflagellar rod protein, PFR1, and its stage-specific localization in Trypanosoma cruzi. PloS one 20120101
Combined contribution of endothelial relaxing autacoides in the rat femoral artery response to CPCA: an adenosine A2 receptor agonist. TheScientificWorldJournal 20120101
L-arginine intake effect on adenine nucleotide metabolism in rat parenchymal and reproductive tissues. TheScientificWorldJournal 20120101
Effects of fatty acid treatments on the dexamethasone-induced intramuscular lipid accumulation in chickens. PloS one 20120101
The chemoselective reduction of isoxazoline γ-lactams through iminium Aza-Diels-Alder reactions: a short-cut synthesis of aminols as valuable intermediates towards nucleoside derivatives. TheScientificWorldJournal 20120101
The expression of small regulatory RNAs in clinical samples reflects the different life styles of Staphylococcus aureus in colonization vs. infection. PloS one 20120101
Traffic-related air pollution and DNA damage: a longitudinal study in Taiwanese traffic conductors. PloS one 20120101
Murine 3T3-L1 adipocyte cell differentiation model: validated reference genes for qPCR gene expression analysis. PloS one 20120101
The plant mitochondrial carrier family: functional and evolutionary aspects. Frontiers in plant science 20120101
Adenosine Methylation in Arabidopsis mRNA is Associated with the 3' End and Reduced Levels Cause Developmental Defects. Frontiers in plant science 20120101
An expanding role for purine uptake permease-like transporters in plant secondary metabolism. Frontiers in plant science 20120101
Acetaminophen induced cytotoxicity and altered gene expression in cultured cardiomyocytes of h(9)c(2) cells. Environmental health and toxicology 20120101
Transport proteins regulate the flux of metabolites and cofactors across the membrane of plant peroxisomes. Frontiers in plant science 20120101
Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line. Nucleosides, nucleotides & nucleic acids 20120101
Oxidative stress and heart failure in altered thyroid States. TheScientificWorldJournal 20120101
Is a genome a codeword of an error-correcting code? PloS one 20120101
Targeting the Immune System to Fight Cancer Using Chemical Receptor Homing Vectors Carrying Polyinosine/Cytosine (PolyIC). Frontiers in oncology 20120101
Glycogen Synthesis is Induced in Hypoxia by the Hypoxia-Inducible Factor and Promotes Cancer Cell Survival. Frontiers in oncology 20120101
Chemical constituents and biological activities of the genus Subergorgia. Pharmacognosy reviews 20120101
Mast cell chemotaxis - chemoattractants and signaling pathways. Frontiers in immunology 20120101
Thermodynamics of aryl-dihydroxyphenyl-thiadiazole binding to human Hsp90. PloS one 20120101
Metal Ion Chelates as Surrogates of Nucleobases for the Recognition of Nucleic Acid Sequences: The Pd(2+) Complex of 2,6-Bis(3,5-dimethylpyrazol-1-yl)purine Riboside. Journal of nucleic acids 20120101
Effect and safety of mycophenolate mofetil or sodium in systemic sclerosis-associated interstitial lung disease: a meta-analysis. Pulmonary medicine 20120101
Variable carbon catabolism among Salmonella enterica serovar Typhi isolates. PloS one 20120101
Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism. PloS one 20120101
Low dose vaccination with attenuated Francisella tularensis strain SchuS4 mutants protects against tularemia independent of the route of vaccination. PloS one 20120101
A metabolomic approach to the study of wine micro-oxygenation. PloS one 20120101
Metagenomic and metabolic profiling of nonlithifying and lithifying stromatolitic mats of Highborne Cay, The Bahamas. PloS one 20120101
Phytocontact Dermatitis due to Mustard Seed Mimicking Burn Injury: Report of a Case. Case reports in medicine 20120101
Autoimmunity in CD73/Ecto-5'-nucleotidase deficient mice induces renal injury. PloS one 20120101
Biophysical characterization of the strong stabilization of the RNA triplex poly(U)•poly(A)*poly(U) by 9-O-(ω-amino) alkyl ether berberine analogs. PloS one 20120101
Role of operon aaoSo-mutT in antioxidant defense in Streptococcus oligofermentans. PloS one 20120101
Exploring the midgut transcriptome and brush border membrane vesicle proteome of the rice stem borer, Chilo suppressalis (Walker). PloS one 20120101
Sweepers in the CNS: Microglial Migration and Phagocytosis in the Alzheimer Disease Pathogenesis. International journal of Alzheimer's disease 20120101
Mast cell adenosine receptors function: a focus on the a3 adenosine receptor and inflammation. Frontiers in immunology 20120101
Tolerance-inducing strategies in islet transplantation. International journal of endocrinology 20120101
Deep sequencing of the oral microbiome reveals signatures of periodontal disease. PloS one 20120101
Cycling of Etk and Etp phosphorylation states is involved in formation of group 4 capsule by Escherichia coli. PloS one 20120101
Effect of urine pH changed by dietary intervention on uric acid clearance mechanism of pH-dependent excretion of urinary uric acid. Nutrition journal 20120101
Arsenic toxicity: the effects on plant metabolism. Frontiers in physiology 20120101
An unusual presentation of tumor lysis syndrome in a patient with advanced gastric adenocarcinoma: case report and literature review. Case reports in medicine 20120101
The yin and yang of yeast transcription: elements of a global feedback system between metabolism and chromatin. PloS one 20120101
A coevolutionary residue network at the site of a functionally important conformational change in a phosphohexomutase enzyme family. PloS one 20120101
The 3' splice site of influenza A segment 7 mRNA can exist in two conformations: a pseudoknot and a hairpin. PloS one 20120101
Mechanism of oxidative stress in neurodegeneration. Oxidative medicine and cellular longevity 20120101
Relationship between human aging muscle and oxidative system pathway. Oxidative medicine and cellular longevity 20120101
The antioxidant mechanisms underlying the aged garlic extract- and S-allylcysteine-induced protection. Oxidative medicine and cellular longevity 20120101
Quercetin Protects against Cadmium-Induced Renal Uric Acid Transport System Alteration and Lipid Metabolism Disorder in Rats. Evidence-based complementary and alternative medicine : eCAM 20120101
Targeted therapy in Ewing sarcoma. ISRN oncology 20120101
Effects of acute creatine supplementation on iron homeostasis and uric acid-based antioxidant capacity of plasma after wingate test. Journal of the International Society of Sports Nutrition 20120101
R-roscovitine reduces lung inflammation induced by lipoteichoic acid and Streptococcus pneumoniae. Molecular medicine (Cambridge, Mass.) 20120101
Overexpression of a maize sulfite oxidase gene in tobacco enhances tolerance to sulfite stress via sulfite oxidation and CAT-mediated H2O2 scavenging. PloS one 20120101
Anti-prion activity of Brilliant Blue G. PloS one 20120101
The antioxidant effects of a polyphenol-rich grape pomace extract in vitro do not correspond in vivo using exercise as an oxidant stimulus. Oxidative medicine and cellular longevity 20120101
Preclinical and clinical evidence of antioxidant effects of antidepressant agents: implications for the pathophysiology of major depressive disorder. Oxidative medicine and cellular longevity 20120101
Optical method for cardiovascular risk marker uric acid removal assessment during dialysis. TheScientificWorldJournal 20120101
Genetics Techniques for Thermococcus kodakarensis. Frontiers in microbiology 20120101
Microbial group specific uptake kinetics of inorganic phosphate and adenosine-5'-triphosphate (ATP) in the north pacific subtropical gyre. Frontiers in microbiology 20120101
Amniotic fluid and amniotic membrane stem cells: marker discovery. Stem cells international 20120101
The association of dietary intake of purine-rich vegetables, sugar-sweetened beverages and dairy with plasma urate, in a cross-sectional study. PloS one 20120101
ATPase cycle and DNA unwinding kinetics of RecG helicase. PloS one 20120101
Proteomic analysis of Neisseria gonorrhoeae biofilms shows shift to anaerobic respiration and changes in nutrient transport and outermembrane proteins. PloS one 20120101
Efficiency of purine utilization by Helicobacter pylori: roles for adenosine deaminase and a NupC homolog. PloS one 20120101
Structural analysis of Staphylococcus aureus serine/threonine kinase PknB. PloS one 20120101
Progression from Sustained BK Viruria to Sustained BK Viremia with Immunosuppression Reduction Is Not Associated with Changes in the Noncoding Control Region of the BK Virus Genome. Journal of transplantation 20120101
Evaluation of DNA damage induced by 2 polybrominated diphenyl ether flame retardants (BDE-47 and BDE-209) in SK-N-MC cells. International journal of toxicology 20120101
Two Cases of Cerebral Involvement in Malignant Lymphoma (CD20+) That Responded to Combination Therapy with Rituximab and Cladribine. Case reports in oncology 20120101
Untargeted plasma metabolite profiling reveals the broad systemic consequences of xanthine oxidoreductase inactivation in mice. PloS one 20120101
Novel cytokinin derivatives do not show negative effects on root growth and proliferation in submicromolar range. PloS one 20120101
Wild-type phosphoribosylpyrophosphate synthase (PRS) from Mycobacterium tuberculosis: a bacterial class II PRS? PloS one 20120101
Transcriptional profiling of serogroup B Neisseria meningitidis growing in human blood: an approach to vaccine antigen discovery. PloS one 20120101
Oxidative damage in various tissues of rats exposed to radon. Journal of toxicology and environmental health. Part A 20120101
Methotrexate Increases Skeletal Muscle GLUT4 Expression and Improves Metabolic Control in Experimental Diabetes. Journal of nutrition and metabolism 20120101
Serum uric acid level is an indicator of total cholesterol and low density lipoprotein cholesterol in men below 45 years in age but not older males. Clinical laboratory 20120101
Mizoribine as sole immunosuppressive agent in islet xenotransplantation models: a candidate immunosuppressant causing no adverse effects on islets. Cell transplantation 20120101
RY-Coding and Non-Homogeneous Models Can Ameliorate the Maximum-Likelihood Inferences From Nucleotide Sequence Data with Parallel Compositional Heterogeneity. Evolutionary bioinformatics online 20120101
Analysis of 5'-mononucleotides in infant formula and adult/pediatric nutritional formula by liquid chromatography: First Action 2011.20. Journal of AOAC International 20120101
HILIC-MS/MS method for the quantitation of nucleotides in infant formula and adult nutritional formula: First Action 2011.21. Journal of AOAC International 20120101
A case of hereditary xanthinuria type 1 accompanied by bilateral renal calculi. Internal medicine (Tokyo, Japan) 20120101
Metabonomics biomarkers for subacute toxicity screening for benzene exposure in mice. Journal of toxicology and environmental health. Part A 20120101
Associations between purine metabolites and clinical symptoms in schizophrenia. PloS one 20120101
Effect of asynchronous transfer on bovine embryonic development and relationship with early cycle uterine proteome profiles. Reproduction, fertility, and development 20120101
Mizoribine treatment for antihistamine-resistant chronic autoimmune urticaria. Dermatologic therapy 20120101
Autoimmune dysregulation and purine metabolism in adenosine deaminase deficiency. Frontiers in immunology 20120101
Tools to kill: genome of one of the most destructive plant pathogenic fungi Macrophomina phaseolina. BMC genomics 20120101
Cerebrospinal fluid metabolome in mood disorders-remission state has a unique metabolic profile. Scientific reports 20120101
Listeria monocytogenes differential transcriptome analysis reveals temperature-dependent Agr regulation and suggests overlaps with other regulons. PloS one 20120101
[Treatment for recurrent hairy cell leukemia]. Terapevticheskii arkhiv 20120101
Potential therapeutic drug target identification in Community Acquired-Methicillin Resistant Staphylococcus aureus (CA-MRSA) using computational analysis. Bioinformation 20120101
Synthesis and antiviral evaluation of alpha-amino acid esters bearing N6-benzyladenine side chain. Acta poloniae pharmaceutica 20120101
Role of supplementary L-carnitine in exercise and exercise recovery. Medicine and sport science 20120101
[Scrining workers employed at the weapons and military technology recycling and disposal facilitie]. Meditsina truda i promyshlennaia ekologiia 20120101
Antihyperalgesic activity of nucleoside transport inhibitors in models of inflammatory pain in guinea pigs. Journal of pain research 20120101
Mycophenolate mofetil (MMF) treatment efficacy in children with primary and secondary glomerulonephritis. Archives of medical science : AMS 20111231
Electron donor-acceptor interactions with flanking purines influence the efficiency of thymine photodimerization. Journal of the American Chemical Society 20111228
A modified alkaline Comet assay for in vivo detection of oxidative DNA damage in Drosophila melanogaster. Mutation research 20111224
Monocyte-specific accessibility of a matrix attachment region in the tumor necrosis factor locus. The Journal of biological chemistry 20111223
Formation of N-N cross-links in DNA by reaction of radiation-produced DNA base pair diradicals: a DFT study. The journal of physical chemistry. B 20111222
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Study of the effect of presence or absence of protozoa on rumen fermentation and microbial protein contribution to the chyme. Journal of animal science 20111201
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Structural insights into the inhibition of cytosolic 5'-nucleotidase II (cN-II) by ribonucleoside 5'-monophosphate analogues. PLoS computational biology 20111201
Comparison and evaluation of different methodologies and tests for detection of anti-dsDNA antibodies on 889 Slovenian patients' and blood donors' sera. Croatian medical journal 20111201
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Moderate exercise training promotes adaptations in coronary blood flow and adenosine production in normotensive rats. Clinics (Sao Paulo, Brazil) 20111201
Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2β in development. PLoS genetics 20111201
High prevalence of drug resistance in animal trypanosomes without a history of drug exposure. PLoS neglected tropical diseases 20111201
Genome comparison of human and non-human malaria parasites reveals species subset-specific genes potentially linked to human disease. PLoS computational biology 20111201
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Treatment of myasthenia gravis based on its immunopathogenesis. Journal of clinical neurology (Seoul, Korea) 20111201
Concordance between Results of Medium-term Liver Carcinogenesis Bioassays and Long-term Findings for Carcinogenic 2-Nitropropane and Non-carcinogenic1-Nitropropane in F344 Rats. Journal of toxicologic pathology 20111201
Inhibition of Inducible Nitric Oxide Synthase Attenuates Monosodium Urate-induced Inflammation in Mice. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20111201
Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics. G3 (Bethesda, Md.) 20111201
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Entropy-driven binding of picomolar transition state analogue inhibitors to human 5'-methylthioadenosine phosphorylase. Biochemistry 20111129
Structural analyses of a purine biosynthetic enzyme from Mycobacterium tuberculosis reveal a novel bound nucleotide. The Journal of biological chemistry 20111125
Direct arylation of 6-phenylpurine and 6-arylpurine nucleosides by ruthenium-catalyzed C-H bond activation. Angewandte Chemie (International ed. in English) 20111125
[Dacarbazine, a chemotherapeutic against metastatic melanoma and a reference drug for new treatment modalities]. Postepy higieny i medycyny doswiadczalnej (Online) 20111123
A metabolic profiling analysis of symptomatic gout in human serum and urine using high performance liquid chromatography-diode array detector technique. Clinica chimica acta; international journal of clinical chemistry 20111120
Fluorescence detection of GDP in real time with the reagentless biosensor rhodamine-ParM. The Biochemical journal 20111115
Synthesis of purine modified 2'-C-methyl nucleosides as potential anti-HCV agents. Bioorganic & medicinal chemistry letters 20111115
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Genome sequencing reveals insights into physiology and longevity of the naked mole rat. Nature 20111110
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Bisphenol A-glycidyl methacrylate induces a broad spectrum of DNA damage in human lymphocytes. Archives of toxicology 20111101
Clofarabine and high-dose cytosine arabinoside in the treatment of refractory or relapsed acute myeloid leukaemia. Annals of hematology 20111101
Ultra-diffuse hydrothermal venting supports Fe-oxidizing bacteria and massive umber deposition at 5000 m off Hawaii. The ISME journal 20111101
The protective effects of inosine against chemical hypoxia on cultured rat oligodendrocytes. Cellular and molecular neurobiology 20111101
Effects of levosimendan on cardiac gene expression profile and post-infarct cardiac remodelling in diabetic Goto-Kakizaki rats. Basic & clinical pharmacology & toxicology 20111101
Identification of novel molecular targets regulated by tumor suppressive miR-1/miR-133a in maxillary sinus squamous cell carcinoma. International journal of oncology 20111101
On the evolution of arterial vascular patterns of tetrapods. Journal of morphology 20111101
Death receptor 5 and cellular FLICE-inhibitory protein regulate pemetrexed-induced apoptosis in human lung cancer cells. European journal of cancer (Oxford, England : 1990) 20111101
Highly regioselective synthesis of undecylenic acid esters of purine nucleosides catalyzed by Candida antarctica lipase B. Biotechnology letters 20111101
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Purine P2Y receptors in ATP-mediated regulation of non-quantal acetylcholine release from motor nerve endings of rat diaphragm. Neuroscience research 20111101
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The polypyrimidine/polypurine motif in the mouse mu opioid receptor gene promoter is a supercoiling-regulatory element. Gene 20111101
Uridine adenosine tetraphosphate induces contraction of airway smooth muscle. American journal of physiology. Lung cellular and molecular physiology 20111101
Evidence for the localization of the Arabidopsis cytokinin receptors AHK3 and AHK4 in the endoplasmic reticulum. Journal of experimental botany 20111101
Decreased oxidative phosphorylation and PGAM deficiency in horses suffering from atypical myopathy associated with acquired MADD. Molecular genetics and metabolism 20111101
Pyrimidine degradation influences germination seedling growth and production of Arabidopsis seeds. Journal of experimental botany 20111101
Gene set analysis of purine and pyrimidine antimetabolites cancer therapies. Pharmacogenetics and genomics 20111101
Shedding of the coronary endothelial glycocalyx: effects of hypoxia/reoxygenation vs ischaemia/reperfusion. British journal of anaesthesia 20111101
Advances in acute lymphoblastic leukemia in adults. Current opinion in oncology 20111101
KRN5500, a spicamycin derivative, exerts anti-myeloma effects through impairing both myeloma cells and osteoclasts. British journal of haematology 20111101
Stability and mismatch discrimination of locked nucleic acid-DNA duplexes. Biochemistry 20111101
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An HPLC-based assay of adenylosuccinate lyase in erythrocytes. Nucleosides, nucleotides & nucleic acids 20111101
Synthesis of (glycopyranosyl-triazolyl)-purines and their inhibitory activities against protein tyrosine phosphatase 1B (PTP1B). Chemistry & biodiversity 20111101
The ADA*2 allele of the adenosine deaminase gene (20q13.11) and recurrent spontaneous abortions: an age-dependent association. Clinics (Sao Paulo, Brazil) 20111101
The role of the P2X₇ receptor in infectious diseases. PLoS pathogens 20111101
Evolution of multidrug resistance during Staphylococcus aureus infection involves mutation of the essential two component regulator WalKR. PLoS pathogens 20111101
EBV tegument protein BNRF1 disrupts DAXX-ATRX to activate viral early gene transcription. PLoS pathogens 20111101
Serratia symbiotica from the aphid Cinara cedri: a missing link from facultative to obligate insect endosymbiont. PLoS genetics 20111101
Bis(7-amino-1,2,4-triazolo[1,5-a]pyrimidin-4-ium) bis-(oxalato-κO,O)cuprate(II) dihydrate. Acta crystallographica. Section E, Structure reports online 20111101
Experimental determination and prediction of bilitranslocase transport activity. Analytica chimica acta 20111031
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Rat liver mitochondrial proteome: changes associated with aging and acetyl-L-carnitine treatment. Journal of proteomics 20111019
Therapy related acute myeloid leukemia with t(10:16): a rare entity. Hematology reports 20111019
Fluorescent properties and conformational preferences of C-linked phenolic-DNA adducts. Chemical research in toxicology 20111017
Discovery of potent, metabolically stable purine CRF-1 antagonists with differentiated binding kinetic profiles. Bioorganic & medicinal chemistry letters 20111015
Novel 4-azasteroidal N-glycoside analogues bearing sugar-like D ring: synthesis and anticancer activities. Bioorganic & medicinal chemistry letters 20111015
Biochemical regulation of sleep and sleep biomarkers. Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine 20111015
Identification and modeling of a phosphatase-like domain in a tRNA 2'-O-ribosyl phosphate transferase Rit1p. Cell cycle (Georgetown, Tex.) 20111015
Complete genome sequence of Staphylothermus hellenicus P8. Standards in genomic sciences 20111015
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Antioxidants, redox signaling, and pathophysiology in schizophrenia: an integrative view. Antioxidants & redox signaling 20111001
Therapeutic management of chronic lymphocytic leukaemia: state of the art and future perspectives. Critical reviews in oncology/hematology 20111001
Extracorporeal photopheresis in addition to pentostatin in conditioning for canine hematopoietic cell transplantation: role in engraftment. Bone marrow transplantation 20111001
Urine alkalinization may be enough for the treatment of bilateral renal pelvis stones associated with Lesch-Nyhan syndrome. Urological research 20111001
Elevated airway purines in COPD. Chest 20111001
Links between hydrothermal environments, pyrophosphate, na(+), and early evolution. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20111001
Adsorption of ribose nucleotides on manganese oxides with varied mn/o ratio: implications for chemical evolution. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20111001
Unraveling the structural and functional differences between purine nucleoside phosphorylase and 5'-deoxy-5'-methylthioadenosine phosphorylase from the archaeon Pyrococcus furiosus. Biochimica et biophysica acta 20111001
Analysis of muscle and ovary transcriptome of Sus scrofa: assembly, annotation and marker discovery. DNA research : an international journal for rapid publication of reports on genes and genomes 20111001
Triplet-state dynamics of a metalloporphyrin photosensitiser (PtTMPyP4) in the presence of halides and purine mononucleotides. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20111001
Structure-activity relationships on purine and 2,3-dihydropurine derivatives as antitubercular agents: a data mining approach. Chemical biology & drug design 20111001
Phosphoribosylamidotransferase, the first enzyme for purine de novo synthesis, is required for conidiation in the sclerotial mycoparasite Coniothyrium minitans. Fungal genetics and biology : FG & B 20111001
A universal real-time assay for the detection of Lyssaviruses. Journal of virological methods 20111001
Profile-statistical periodicity of DNA coding regions. DNA research : an international journal for rapid publication of reports on genes and genomes 20111001
Identification of serum biomarkers of hepatocarcinoma through liquid chromatography/mass spectrometry-based metabonomic method. Analytical and bioanalytical chemistry 20111001
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[Clinical strategies for prevention of drug-induced urinary calculi]. Clinical calcium 20111001
Synthesis of novel 6'-spirocyclopropyl-5'-norcarbocyclic adenosine phosphonic Acid analogues as potent anti-hiv agents. Nucleosides, nucleotides & nucleic acids 20111001
Design and synthesis of carbocyclic versions of furanoid nucleoside phosphonic Acid analogues as potential anti-hiv agents. Nucleosides, nucleotides & nucleic acids 20111001
Changes in renal function after different tandem hematopoietic stem-cell transplantation approaches in patients with multiple myeloma. Journal of Korean medical science 20111001
Endophytic life strategies decoded by genome and transcriptome analyses of the mutualistic root symbiont Piriformospora indica. PLoS pathogens 20111001
Effective oral favipiravir (T-705) therapy initiated after the onset of clinical disease in a model of arenavirus hemorrhagic Fever. PLoS neglected tropical diseases 20111001
Ebola virion attachment and entry into human macrophages profoundly effects early cellular gene expression. PLoS neglected tropical diseases 20111001
1-(3-Chloro-phen-yl)-2-methyl-4-nitro-1H-imidazole-5-carboxamide. Acta crystallographica. Section E, Structure reports online 20111001
4-Sulfamoylanilinium nitrate. Acta crystallographica. Section E, Structure reports online 20111001
The molecular biology of frog virus 3 and other iridoviruses infecting cold-blooded vertebrates. Viruses 20111001
Subcellular localization of N-deoxyribosyltransferase in Lactobacillus fermentum: cell surface association of an intracellular nucleotide metabolic enzyme. FEMS microbiology letters 20111001
Protective effect of methanol extract from citrus press cakes prepared by far-infrared radiation drying on H(2)O(2)-mediated oxidative damage in Vero cells. Nutrition research and practice 20111001
[Effect of adenine on metabolic fluxes in Escherichia coli DH5alpha and its acetate-tolerant mutant DA19]. Wei sheng wu xue bao = Acta microbiologica Sinica 20111001
NMR-based substrate analog docking to Escherichia coli peptidyl-tRNA hydrolase. Journal of molecular biology 20110930
High single-drug activity of nelarabine in relapsed T-lymphoblastic leukemia/lymphoma offers curative option with subsequent stem cell transplantation. Blood 20110929
Crystal structure of the β2 adrenergic receptor-Gs protein complex. Nature 20110929
Colourimetric and spectroscopic discrimination between nucleotides and nucleosides using para-sulfonato-calix[4]arene capped silver nanoparticles. Chemical communications (Cambridge, England) 20110928
Interpretation of substituent effects on 13C and 15N NMR chemical shifts in 6-substituted purines. Physical chemistry chemical physics : PCCP 20110921
A prebiotic role for 8-oxoguanosine as a flavin mimic in pyrimidine dimer photorepair. Journal of the American Chemical Society 20110921
Biochemistry of uridine in plasma. Clinica chimica acta; international journal of clinical chemistry 20110918
Mining endonuclease cleavage determinants in genomic sequence data. The Journal of biological chemistry 20110916
Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1). The Journal of biological chemistry 20110916
Synthesis of purine-scaffold fluorescent probes for heat shock protein 90 with use in flow cytometry and fluorescence microscopy. Bioorganic & medicinal chemistry letters 20110915
Activation and inhibition of CTP synthase from Trypanosoma brucei, the causative agent of African sleeping sickness. Bioorganic & medicinal chemistry letters 20110915
2-Oxoglycosyl ('ulosyl') and 2-oximinoglycosyl bromides: versatile donors for the expedient assembly of oligosaccharides with β-D-mannose, β-L-rhamnose, N-acetyl-β-D-mannosamine, and N-acetyl-β-D-mannosaminuronic acid units. Chemical reviews 20110914
Direct C-H arylation of purine on solid phase and its use for chemical libraries synthesis. ACS combinatorial science 20110912
Experimental and theoretical study of the metastable decay of negatively charged nucleosides in the gas phase. Physical chemistry chemical physics : PCCP 20110907
iTRAQ-based quantitative proteomic analysis of Thermobifida fusca reveals metabolic pathways of cellulose utilization. Journal of proteomics 20110906
Fluorescence properties of 8-(2-pyridyl)guanine '2PyG' as compared to 2-aminopurine in DNA. Chembiochem : a European journal of chemical biology 20110905
Physiological and toxic effects of purine intermediate 5-amino-4-imidazolecarboxamide ribonucleotide (AICAR) in yeast. The Journal of biological chemistry 20110902
Global proteomics analysis of testis and ovary in adult zebrafish (Danio rerio). Fish physiology and biochemistry 20110901
RNA and protein 3D structure modeling: similarities and differences. Journal of molecular modeling 20110901
Effect of training load structure on purine metabolism in middle-distance runners. Medicine and science in sports and exercise 20110901
Pharmacochemistry of the platelet purinergic receptors. Purinergic signalling 20110901
Anti-angiogenic effects of purine inhibitors of cyclin dependent kinases. Angiogenesis 20110901
Technical note: The persistence of microbial-specific DNA sequences through gastric digestion in lambs and their potential use as microbial markers. Journal of animal science 20110901
Suppression of inflammation response by a novel A₃ adenosine receptor agonist thio-Cl-IB-MECA through inhibition of Akt and NF-κB signaling. Immunobiology 20110901
The improvement of riboflavin production in Ashbya gossypii via disparity mutagenesis and DNA microarray analysis. Applied microbiology and biotechnology 20110901
Hypoglycemia and glycemic variability among children with acute lymphoblastic leukemia during maintenance therapy. Leukemia & lymphoma 20110901
B-DNA to zip-DNA: simulating a DNA transition to a novel structure with enhanced charge-transport characteristics. The journal of physical chemistry. A 20110901
Gene expression profiling of peripheral blood leukocytes identifies and validates ABCB1 as a novel biomarker for Alzheimer's disease. Neurobiology of disease 20110901
Validation of the catalytic mechanism of Escherichia coli purine nucleoside phosphorylase by structural and kinetic studies. Biochimie 20110901
purL gene expression affects biofilm formation and symbiotic persistence of Photorhabdus temperata in the nematode Heterorhabditis bacteriophora. Microbiology (Reading, England) 20110901
Effect of growth under selection on appearance of chromosomal mutations in Salmonella enterica. Genetics 20110901
Impact of histidine residue on chelating ability of 2'-deoxyriboadenosine. Journal of inorganic biochemistry 20110901
Safety and efficacy of febuxostat treatment in subjects with gout and severe allopurinol adverse reactions. The Journal of rheumatology 20110901
Enzymatic dissolution of calcium and struvite crystals: in vitro evaluation of biochemical requirements. Urology 20110901
Identification of immunodeficient molecules in neonatal mononuclear cells by proteomic differential displays. Proteomics 20110901
Mathematical modeling predicts the effect of folate deficiency and excess on cancer-related biomarkers. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110901
Xanthine oxidoreductase: a journey from purine metabolism to cardiovascular excitation-contraction coupling. Critical reviews in biotechnology 20110901
Expression of the 2',3'-cAMP-adenosine pathway in astrocytes and microglia. Journal of neurochemistry 20110901
NMR structure of a 4 x 4 nucleotide RNA internal loop from an R2 retrotransposon: identification of a three purine-purine sheared pair motif and comparison to MC-SYM predictions. RNA (New York, N.Y.) 20110901
Potential teratogenic effects of allopurinol: a case report. American journal of medical genetics. Part A 20110901
A decade of targets and patented drugs for chemotherapy of Chagas disease. Recent patents on anti-infective drug discovery 20110901
Probing conformational states of glutaryl-CoA dehydrogenase by fragment screening. Acta crystallographica. Section F, Structural biology and crystallization communications 20110901
Plasmodium protease ROM1 is important for proper formation of the parasitophorous vacuole. PLoS pathogens 20110901
A diverse population of Cryptococcus gattii molecular type VGIII in southern Californian HIV/AIDS patients. PLoS pathogens 20110901
Chronic arsenic toxicity: studies in West Bengal, India. The Kaohsiung journal of medical sciences 20110901
A case of exercise-induced acute renal failure with G774A mutation in SCL22A12 causing renal hypouricemia. Journal of Korean medical science 20110901
Urate transporters: an evolving field. Seminars in nephrology 20110901
8-(2-Hy-droxy-phen-yl)-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione. Acta crystallographica. Section E, Structure reports online 20110901
Low-grade lymphoma: Beyond fludarabine-single therapy. The Korean journal of hematology 20110901
Fludarabine-containing chemotherapy for patients with previously untreated low-grade non-Hodgkin's lymphoma. The Korean journal of hematology 20110901
Expressed sequence tag analysis of the erythrocytic stage of Plasmodium berghei. The Korean journal of parasitology 20110901
New insights into neuromyelitis optica. Journal of clinical neurology (Seoul, Korea) 20110901
Organic grape juice intake improves functional capillary density and postocclusive reactive hyperemia in triathletes. Clinics (Sao Paulo, Brazil) 20110901
First Steps Towards an Understanding of a Mode ofCarcinogenic Action for Vanadium Pentoxide. Journal of toxicologic pathology 20110901
Effects of ramadan fasting on biochemical and anthropometric parameters in physically active men. Asian journal of sports medicine 20110901
Autoimmune neuromuscular disorders. Current neuropharmacology 20110901
Multiple sclerosis: pathogenesis and treatment. Current neuropharmacology 20110901
Idiopathic transverse myelitis and neuromyelitis optica: clinical profiles, pathophysiology and therapeutic choices. Current neuropharmacology 20110901
Neuropsychiatric systemic lupus erythematosus. Current neuropharmacology 20110901
Toxicities of immunosuppressive treatment of autoimmune neurologic diseases. Current neuropharmacology 20110901
Pt(II) coordination to N1 of 9-methylguanine: why it facilitates binding of additional metal ions to the purine ring. Chemistry (Weinheim an der Bergstrasse, Germany) 20110829
2'-Fluoro substituents can mimic native 2'-hydroxyls within structured RNA. Chemistry & biology 20110826
In vitro efficacy of forodesine and nelarabine (ara-G) in pediatric leukemia. Blood 20110825
Adenosine deaminase-like protein 1 (ADAL1): characterization and substrate specificity in the hydrolysis of N(6)- or O(6)-substituted purine or 2-aminopurine nucleoside monophosphates. Journal of medicinal chemistry 20110825
Hematopoietic stem cell gene therapy for adenosine deaminase-deficient severe combined immunodeficiency leads to long-term immunological recovery and metabolic correction. Science translational medicine 20110824
B family DNA polymerases asymmetrically recognize pyrimidines and purines. Biochemistry 20110823
CSF xanthine, homovanillic acid, and their ratio as biomarkers of Parkinson's disease. Brain research 20110823
Two parallel pathways in the kinetic sequence of the dihydrofolate reductase from Mycobacterium tuberculosis. Biochemistry 20110816
Structure-activity relationships for the interactions of 2'- and 3'-(O)-(N-methyl)anthraniloyl-substituted purine and pyrimidine nucleotides with mammalian adenylyl cyclases. Biochemical pharmacology 20110815
Increasing the speed limit for hole transport in DNA. Journal of the American Chemical Society 20110803
Interactions of cations with RNA loop-loop complexes. Biophysical journal 20110803
Coupled nucleotide and mucin hypersecretion from goblet-cell metaplastic human airway epithelium. American journal of respiratory cell and molecular biology 20110801
Arbuscular mycorrhizal symbiosis elicits proteome responses opposite of P-starvation in SO4 grapevine rootstock upon root colonisation with two Glomus species. Mycorrhiza 20110801
High throughput screening of small molecule libraries for modifiers of radiation responses. International journal of radiation biology 20110801
Effects of ischemia and reperfusion on P2X2 receptor expressing neurons of the rat ileum enteric nervous system. Digestive diseases and sciences 20110801
Completing the purine utilisation pathway of Aspergillus nidulans. Fungal genetics and biology : FG & B 20110801
De novo engineering and metabolic flux analysis of inosine biosynthesis in Bacillus subtilis. Biotechnology letters 20110801
Alterations in DNA metabolism in Elliptio complanata mussels after exposure to municipal effluents. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110801
Association of the 5-aminoimidazole-4-carboxamide ribonucleotide transformylase gene with response to methotrexate in juvenile idiopathic arthritis. Annals of the rheumatic diseases 20110801
Electrochemical behaviour of carbon paste electrodes enriched with tin oxide nanoparticles using voltammetry and electrochemical impedance spectroscopy. Colloids and surfaces. B, Biointerfaces 20110801
Uridine adenosine tetraphosphate-induced contraction is increased in renal but not pulmonary arteries from DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology 20110801
Sustained activation of ERK and Cdk2/cyclin-A signaling pathway by pemetrexed leading to S-phase arrest and apoptosis in human non-small cell lung cancer A549 cells. European journal of pharmacology 20110801
Extracellular purine metabolism and signaling of CD73-derived adenosine in murine Treg and Teff cells. American journal of physiology. Cell physiology 20110801
Significantly increased risk of carotid atherosclerosis with arsenic exposure and polymorphisms in arsenic metabolism genes. Environmental research 20110801
Increased glutamine in leaves of poplar transgenic with pine GS1a caused greater anthranilate synthetase α-subunit (ASA1) transcript and protein abundances: an auxin-related mechanism for enhanced growth in GS transgenics? Journal of experimental botany 20110801
Equilibrative nucleoside transporter 1 (ENT1) is critical for pollen germination and vegetative growth in Arabidopsis. Journal of experimental botany 20110801
Which one among the Pt-containing anticancer drugs more easily forms monoadducts with G and A DNA bases? A comparative study among oxaliplatin, nedaplatin, and carboplatin. Inorganic chemistry 20110801
Synthesis and antiviral evaluation of 9-(S)-[3-alkoxy-2-(phosphonomethoxy)propyl]nucleoside alkoxyalkyl esters: inhibitors of hepatitis C virus and HIV-1 replication. Bioorganic & medicinal chemistry 20110801
A model of proto-anti-codon RNA enzymes requiring L-amino acid homochirality. Journal of molecular evolution 20110801
The lifestyle of the segmented filamentous bacterium: a non-culturable gut-associated immunostimulating microbe inferred by whole-genome sequencing. DNA research : an international journal for rapid publication of reports on genes and genomes 20110801
Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta crystallographica. Section D, Biological crystallography 20110801
Inflammatory bowel disease: perioperative pharmacological considerations. Mayo Clinic proceedings 20110801
Enzyme kinetics of the mitochondrial deoxyribonucleoside salvage pathway are not sufficient to support rapid mtDNA replication. PLoS computational biology 20110801
Variance of gene expression identifies altered network constraints in neurological disease. PLoS genetics 20110801
[Novel conventional therapies in onco-hemathology]. Bulletin du cancer 20110801
Salmonella bongori provides insights into the evolution of the Salmonellae. PLoS pathogens 20110801
Improving the outcomes of elderly patients with acute myeloid leukemia in a Brazilian University Hospital. Clinics (Sao Paulo, Brazil) 20110801
Effects of mycophenolate sodium on mucociliary clearance using a bronchial section and anastomosis rodent model. Clinics (Sao Paulo, Brazil) 20110801
Modes of action of microbially-produced phytotoxins. Toxins 20110801
Complications of nephrotic syndrome. Korean journal of pediatrics 20110801
Genetics and mitochondrial abnormalities in autism spectrum disorders: a review. Current genomics 20110801
Genomic organization of leishmania species. Iranian journal of parasitology 20110801
Pecularities of prolonged use of moxonidine in patients with hypertension associated with metabolic syndrome. Bulletin of experimental biology and medicine 20110801
Difficult-to-treat gouty arthritis: a disease warranting better management. Drugs 20110730
Peculiarities of homooligonucleotides wrapping around carbon nanotubes: molecular dynamics modeling. The journal of physical chemistry. B 20110728
High-sensitivity capillary electrophoresis method for monitoring purine nucleoside phosphorylase and adenosine deaminase reactions by a reversed electrode polarity switching mode. Journal of chromatography. A 20110722
Allosteric nucleotide-binding site in the mitochondrial NADH:ubiquinone oxidoreductase (respiratory complex I). FEBS letters 20110721
CuBr catalyzed C-N cross coupling reaction of purines and diaryliodonium salts to 9-arylpurines. Organic & biomolecular chemistry 20110721
Strengthening the stability of a tunnel-shaped homotetramer protein with nanogels. The journal of physical chemistry. B 20110721
Repair of the major lesion resulting from C5'-oxidation of DNA. Biochemistry 20110719
γ-Hydroxy-1,N2-propano-2'-deoxyguanosine DNA adduct conjugates the N-terminal amine of the KWKK peptide via a carbinolamine linkage. Chemical research in toxicology 20110718
SAR studies of 9-norbornylpurines as Coxsackievirus B3 inhibitors. Bioorganic & medicinal chemistry letters 20110715
Progress in structure based drug design for G protein-coupled receptors. Journal of medicinal chemistry 20110714
Escherichia coli Fpg glycosylase is nonrendundant and required for the rapid global repair of oxidized purine and pyrimidine damage in vivo. Journal of molecular biology 20110708
Approaches to enzyme and substrate design of the murine Dnmt3a DNA methyltransferase. Chembiochem : a European journal of chemical biology 20110704
Novel 1,2,4-triazole and purine acyclic cyclopropane nucleoside analogues: synthesis, antiviral and cytostatic activity evaluations. Antiviral chemistry & chemotherapy 20110704
Manipulations of AMP metabolic genes increase growth rate and cold tolerance in Escherichia coli: implications for psychrophilic evolution. Molecular biology and evolution 20110701
An animal model for measuring the effect of common NICU procedures on ATP metabolism. Biological research for nursing 20110701
Regulation of the polymeric immunoglobulin receptor by the classical and alternative NF-κB pathways in intestinal epithelial cells. Mucosal immunology 20110701
The biochemistry of nitrogen mobilization: purine ring catabolism. Trends in plant science 20110701
Regulation of pentose utilisation by AraR, but not XlnR, differs in Aspergillus nidulans and Aspergillus niger. Applied microbiology and biotechnology 20110701
Structural basis for the high-affinity inhibition of mammalian membranous adenylyl cyclase by 2',3'-o-(N-methylanthraniloyl)-inosine 5'-triphosphate. Molecular pharmacology 20110701
Xanthine oxidase inhibitors: a patent survey. Expert opinion on therapeutic patents 20110701
In vitro and in vivo biological activity screening of Ru(III) complexes involving 6-benzylaminopurine derivatives with higher pro-apoptotic activity than NAMI-A. Journal of inorganic biochemistry 20110701
The effect of red pigment on the amyloidization of yeast proteins. Yeast (Chichester, England) 20110701
Receptor-like activity evoked by extracellular ADP in Arabidopsis root epidermal plasma membrane. Plant physiology 20110701
Clofarabine for myelodysplastic syndromes. Expert opinion on investigational drugs 20110701
Arabidopsis thaliana nucleosidase mutants provide new insights into nucleoside degradation. The New phytologist 20110701
Synthesis of purine nucleosides built on a 3-oxabicyclo[3.2.0]heptane scaffold. The Journal of organic chemistry 20110701
Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction. Nature structural & molecular biology 20110701
Molecular basis of P2-receptor-mediated calcium signaling in activated pancreatic stellate cells. Pancreas 20110701
Identification of prognostic factors for plerixafor-based hematopoietic stem cell mobilization. American journal of hematology 20110701
The human caveolin 1 gene upstream purine complex and neurodegeneration--a common signature. Journal of neuroimmunology 20110701
Pharmacokinetic properties of infliximab in children and adults with Crohn's disease: a retrospective analysis of data from 2 phase III clinical trials. Clinical therapeutics 20110701
Functional and molecular interactions between ERK and CHK2 in diffuse large B-cell lymphoma. Nature communications 20110701
Treatment of elderly patients with mantle cell lymphoma. Seminars in hematology 20110701
In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis. PLoS pathogens 20110701
Improved PCR-RFLP for the detection of diminazene resistance in Trypanosoma congolense under field conditions using filter papers for sample storage. PLoS neglected tropical diseases 20110701
Alcohol consumption and oxidative DNA damage. International journal of environmental research and public health 20110701
[Mutation analysis of the purine operon leader region in Bacillus subtilis]. Genetika 20110701
Preventive and therapeutic strategies for bovine leukemia virus: lessons for HTLV. Viruses 20110701
[Different expression of protein in the supernatant of heat injured keratinocytes]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery 20110701
Pretreatment metabotype as a predictor of response to sertraline or placebo in depressed outpatients: a proof of concept. Translational psychiatry 20110701
Opposite effect of ATP on contraction force of tonic and phasic skeletal muscles in frogs. Bulletin of experimental biology and medicine 20110701
Characterization of an ecto-5'-nucleotidase activity present on the cell surface of Tritrichomonas foetus. Veterinary parasitology 20110630
Combined effect of CYP1B1, COMT, GSTP1, and MnSOD genotypes and risk of postmenopausal breast cancer. Journal of gynecologic oncology 20110630
Analysis of regulation of pentose utilisation in Aspergillus niger reveals evolutionary adaptations in Eurotiales. Studies in mycology 20110630
Transition-state analysis of Trypanosoma cruzi uridine phosphorylase-catalyzed arsenolysis of uridine. Journal of the American Chemical Society 20110629
Reduced intensity transplantation for primary immunodeficiency disorders. Pediatric reports 20110622
Aplastic anemia: immunosuppressive therapy in 2010. Pediatric reports 20110622
Novel chemically defined approach to produce multipotent cells from terminally differentiated tissue syncytia. ACS chemical biology 20110617
Molecular chemotherapy and chemotherapy: a new front against late-stage hormone-refractory prostate cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20110615
Inhibition of xanthine oxidase by thiosemicarbazones, hydrazones and dithiocarbazates derived from hydroxy-substituted benzaldehydes. ChemMedChem 20110606
Evidence for the existence of a specific g protein-coupled receptor activated by guanosine. ChemMedChem 20110606
Endoplasmic reticulum Ca2+ release modulates endothelial nitric-oxide synthase via extracellular signal-regulated kinase (ERK) 1/2-mediated serine 635 phosphorylation. The Journal of biological chemistry 20110603
A review of pharmacologic options for previously untreated chronic lymphocytic leukemia. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110601
Adenosine deaminase in saliva as a diagnostic marker of squamous cell carcinoma of tongue. Clinical oral investigations 20110601
Homochiral selectivity in RNA synthesis: montmorillonite-catalyzed quaternary reactions of D, L-purine with D, L- pyrimidine nucleotides. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20110601
Low-molecular-mass purine nucleoside phosphorylase: characterization and application in enzymatic synthesis of nucleoside antiviral drugs. Biotechnology letters 20110601
Microbial community and metabolomic comparison of irritable bowel syndrome faeces. Journal of medical microbiology 20110601
N9-substituted derivatives of kinetin: effective anti-senescence agents. Phytochemistry 20110601
Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase. Cancer gene therapy 20110601
Mutational analysis of the major soybean UreF paralogue involved in urease activation. Journal of experimental botany 20110601
A link between impaired purine nucleotide synthesis and apoptosis in Drosophila melanogaster. Genetics 20110601
Implications of minimal residual disease in hairy cell leukemia after cladribine using immunohistochemistry and immunophenotyping. Leukemia & lymphoma 20110601
Purine analog toxicity in patients with hairy cell leukemia. Leukemia & lymphoma 20110601
Characterization of mitochondrial mRNAs in codfish reveals unique features compared to mammals. Current genetics 20110601
Infectious complications in hairy cell leukemia. Leukemia & lymphoma 20110601
Rituximab with pentostatin or cladribine: an effective combination treatment for hairy cell leukemia after disease recurrence. Leukemia & lymphoma 20110601
A patient's point of view. Leukemia & lymphoma 20110601
Nucleotide promiscuity of 3-phosphoglycerate kinase is in focus: implications for the design of better anti-HIV analogues. Molecular bioSystems 20110601
Insulin restores gestational diabetes mellitus-reduced adenosine transport involving differential expression of insulin receptor isoforms in human umbilical vein endothelium. Diabetes 20110601
Nucleotide receptors as targets in the pharmacological enhancement of dermal wound healing. Purinergic signalling 20110601
Purine metabolism, immune reconstitution, and abdominal adipose tumor after gene therapy for adenosine deaminase deficiency. The Journal of allergy and clinical immunology 20110601
Synthesis and antimycobacterial activities of non-purine analogs of 6-aryl-9-benzylpurines: Imidazopyridines, pyrrolopyridines, benzimidazoles, and indoles. Bioorganic & medicinal chemistry 20110601
Allopurinol, uric acid, and oxidative stress in cardiorenal disease. International urology and nephrology 20110601
Long-term results for pentostatin and cladribine treatment of hairy cell leukemia. Leukemia & lymphoma 20110601
Hairy cell leukemia: a successful model for experimental therapeutics--pentostatin and new ideas. Leukemia & lymphoma 20110601
Management of hairy cell leukemia variant. Leukemia & lymphoma 20110601
Recombinant immunotoxins and other therapies for relapsed/refractory hairy cell leukemia. Leukemia & lymphoma 20110601
Molecular variant of hairy cell leukemia with poor prognosis. Leukemia & lymphoma 20110601
Effects of feeding different levels of dietary fiber through the addition of corn stover on nutrient utilization of dairy heifers precision-fed high and low concentrate diets. Journal of dairy science 20110601
Introductory overview of purinergic signalling. Frontiers in bioscience (Elite edition) 20110601
Purinoceptors in inflammation: potential as anti-inflammatory therapeutic targets. Frontiers in bioscience (Landmark edition) 20110601
Differences in dinucleotide frequencies of thermophilic genes encoding water soluble and membrane proteins. Journal of Zhejiang University. Science. B 20110601
Progress in the preclinical discovery and clinical development of class I and dual class I/IV phosphoinositide 3-kinase (PI3K) inhibitors. Current medicinal chemistry 20110601
The genetic basis of panic disorder. Journal of Korean medical science 20110601
The therapeutic potential of adenosine triphosphate as an immune modulator in the treatment of HIV/AIDS: a combination approach with HAART. Current HIV research 20110601
A new view of the bacterial cytosol environment. PLoS computational biology 20110601
A large gene network in immature erythroid cells is controlled by the myeloid and B cell transcriptional regulator PU.1. PLoS genetics 20110601
Pathways of distinction analysis: a new technique for multi-SNP analysis of GWAS data. PLoS genetics 20110601
Correlation between cold and hot pattern in traditional Chinese medicine and gene expression profiles in rheumatoid arthritis. Frontiers of medicine 20110601
1-Acetyl-6-bromo-1H-imidazo[4,5-b]pyridin-2(3H)-one. Acta crystallographica. Section E, Structure reports online 20110601
7,9-Bis(hy-droxy-meth-yl)-7H-purine-2,6,8(1H,3H,9H)trione. Acta crystallographica. Section E, Structure reports online 20110601
Animal models of intellectual disability: towards a translational approach. Clinics (Sao Paulo, Brazil) 20110601
Novel mutations in the human HPRT gene. Nucleosides, nucleotides & nucleic acids 20110601
[Mycophenolate mofetil as a novel treatment for lupus nephritis]. Harefuah 20110601
Gammaretroviral vectors: biology, technology and application. Viruses 20110601
4-Pyridone-3-carboxamide-1-β-D-ribonucleoside triphosphate (4PyTP), a novel NAD metabolite accumulating in erythrocytes of uremic children: a biomarker for a toxic NAD analogue in other tissues? Toxins 20110601
Nuclear Factor κB and Adenosine Receptors: Biochemical and Behavioral Profiling. Current neuropharmacology 20110601
The utility of uric acid assay in dogs as an indicator of functional hepatic mass. Journal of the South African Veterinary Association 20110601
[Bioinformatics analysis of nicotinamide phosphoribosyl transferase of Schistosoma japonicum]. Zhongguo xue xi chong bing fang zhi za zhi = Chinese journal of schistosomiasis control 20110601
Toxicological pathology in the rat placenta. Journal of toxicologic pathology 20110601
Identification of epigenetic regulators of a transcriptionally silenced transgene in maize. G3 (Bethesda, Md.) 20110601
RCL hydrolyzes 2'-deoxyribonucleoside 5'-monophosphate via formation of a reaction intermediate. Biochemistry 20110531
Treponema denticola PurE Is a bacterial AIR carboxylase. Biochemistry 20110531
Molecular recognition at the active site of catechol-O-methyltransferase (COMT): adenine replacements in bisubstrate inhibitors. Chemistry (Weinheim an der Bergstrasse, Germany) 20110527
Contiguous metal-mediated base pairs comprising two Ag(I) ions. Chemistry (Weinheim an der Bergstrasse, Germany) 20110527
Kinetic mechanism for the excision of hypoxanthine by Escherichia coli AlkA and evidence for binding to DNA ends. Biochemistry 20110524
Palladium-catalyzed C-H bond functionalization of C6-arylpurines. Chemical communications (Cambridge, England) 20110521
Presence of divalent cation is not mandatory for the formation of intramolecular purine-motif triplex containing human c-jun protooncogene target. Biochemistry 20110517
Hypoxanthine guanine phosphoribosyltransferase distorts the purine ring of nucleotide substrates and perturbs the pKa of bound xanthosine monophosphate. Biochemistry 20110517
(5'S)-8,5'-cyclo-2'-deoxyguanosine is a strong block to replication, a potent pol V-dependent mutagenic lesion, and is inefficiently repaired in Escherichia coli. Biochemistry 20110517
Extracellular nucleotide derivatives protect cardiomyocytes against hypoxic stress. Biochemical pharmacology 20110515
NMR structures of apo L. casei dihydrofolate reductase and its complexes with trimethoprim and NADPH: contributions to positive cooperative binding from ligand-induced refolding, conformational changes, and interligand hydrophobic interactions. Biochemistry 20110510
A role for nucleotides in support of breast cancer angiogenesis: heterologous receptor signalling. British journal of cancer 20110510
Integrated analysis of ATM mediated gene and protein expression impacting cellular metabolism. Journal of proteome research 20110506
Combined metabonomic and quantitative real-time PCR analyses reveal systems metabolic changes of Fusarium graminearum induced by Tri5 gene deletion. Journal of proteome research 20110506
Synthesis of 2'-O-[2-(N-methylcarbamoyl)ethyl]ribonucleosides using oxa-Michael reaction and chemical and biological properties of oligonucleotide derivatives incorporating these modified ribonucleosides. The Journal of organic chemistry 20110506
Cloning and characterization of purine nucleoside phosphorylase in Escherichia coli and subsequent ribavirin biosynthesis using immobilized recombinant cells. Enzyme and microbial technology 20110506
Caffeine and uric acid mediate glutathione synthesis for neuroprotection. Neuroscience 20110505
Identification and characterization of small-molecule inducers of fetal hemoglobin. ChemMedChem 20110502
Stability and structure of mixed-ligand metal ion complexes that contain Ni2+, Cu2+, or Zn2+, and Histamine, as well as adenosine 5'-triphosphate (ATP4-) or uridine 5'-triphosphate (UTP(4-): an intricate network of equilibria. Chemistry (Weinheim an der Bergstrasse, Germany) 20110502
Six-month repeated dose toxicity of orally administered metacavir in rhesus monkeys. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20110501
Pharmacokinetics of clofarabine in patients with high-risk inherited metabolic disorders undergoing brain-sparing hematopoietic cell transplantation. Journal of clinical pharmacology 20110501
Identification of a 2-cell stage specific inhibitor of the cleavage of preimplantation mouse embryos synthesized by rat hepatoma cells as 5'-deoxy-5'-methylthioadenosine. Zygote (Cambridge, England) 20110501
Adenosine receptors and cancer. Biochimica et biophysica acta 20110501
Study on species differences in nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor. Archives of toxicology 20110501
Hematopoietic stem cell mobilization with the reversible CXCR4 receptor inhibitor plerixafor (AMD3100)-Polish compassionate use experience. Annals of hematology 20110501
Metabolomic changes in autopsy-confirmed Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association 20110501
Adenosine and its receptors in the heart: regulation, retaliation and adaptation. Biochimica et biophysica acta 20110501
The pentostatin plus cyclophosphamide nonmyeloablative regimen induces durable host T cell functional deficits and prevents murine marrow allograft rejection. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501
Mechanism of growth inhibition of intraerythrocytic stages of Plasmodium falciparum by 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR). Molecular and biochemical parasitology 20110501
Discovery of a small arterivirus gene that overlaps the GP5 coding sequence and is important for virus production. The Journal of general virology 20110501
A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart. Basic research in cardiology 20110501
Akt, 14-3-3ζ, and vimentin mediate a drug-resistant invasive phenotype in diffuse large B-cell lymphoma. Leukemia & lymphoma 20110501
Beyond glucose: metabolic shifts in responses to the effects of the oral glucose tolerance test and the high-fructose diet in rats. Molecular bioSystems 20110501
Identification of the UMP synthase gene by establishment of uracil auxotrophic mutants and the phenotypic complementation system in the marine diatom Phaeodactylum tricornutum. Plant physiology 20110501
The minor groove-binding agent ELB-21 forms multiple interstrand and intrastrand covalent cross-links with duplex DNA and displays potent bactericidal activity against methicillin-resistant Staphylococcus aureus. The Journal of antimicrobial chemotherapy 20110501
Managing MS in a changing treatment landscape. Journal of neurology 20110501
Shortening infusion time for high-dose methotrexate alters antileukemic effects: a randomized prospective clinical trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110501
Sunitinib in relapsed or refractory diffuse large B-cell lymphoma: a clinical and pharmacodynamic phase II multicenter study of the NCIC Clinical Trials Group. Leukemia & lymphoma 20110501
Uridine correlates with the concentration of fructosamine and HbA1c in children with type 1 diabetes. Acta paediatrica (Oslo, Norway : 1992) 20110501
Educational paper. The expanding clinical and immunological spectrum of severe combined immunodeficiency. European journal of pediatrics 20110501
Waldenström macroglobulinemia: 2011 update on diagnosis, risk stratification, and management. American journal of hematology 20110501
Molecular cloning, overexpression, purification, crystallization and preliminary X-ray diffraction analysis of a purine nucleoside phosphorylase from Bacillus subtilis strain 168. Acta crystallographica. Section F, Structural biology and crystallization communications 20110501
Airway purinergic responses in healthy, atopic nonasthmatic, and atopic asthmatic subjects exposed to ozone. Inhalation toxicology 20110501
Crystal structures of T. b. rhodesiense adenosine kinase complexed with inhibitor and activator: implications for catalysis and hyperactivation. PLoS neglected tropical diseases 20110501
Genetic variation in genes involved in folate and drug metabolism in a south Indian population. Indian journal of human genetics 20110501
Foamy virus biology and its application for vector development. Viruses 20110501
Postoperative care of the transplanted patient. Current cardiology reviews 20110501
Ammonia channeling in Plasmodium falciparum GMP synthetase: investigation by NMR spectroscopy and biochemical assays. Biochemistry 20110426
Inhibition by purine nucleotides of the release of reactive oxygen species from muscle mitochondria: indication for a function of uncoupling proteins as superoxide anion transporters. Biochemical and biophysical research communications 20110422
Local excitation of the 5-bromouracil chromophore in DNA. Computational and UV spectroscopic studies. The journal of physical chemistry. B 20110421
Inosine augments the effects of a Nogo receptor blocker and of environmental enrichment to restore skilled forelimb use after stroke. The Journal of neuroscience : the official journal of the Society for Neuroscience 20110420
Synthesis of fluorinated purine and 1-deazapurine glycosides as potential inhibitors of adenosine deaminase. The Journal of organic chemistry 20110415
Pd(II)-catalyzed ortho arylation of 6-arylpurines with aryl iodides via purine-directed C-H activation: a new strategy for modification of 6-arylpurine derivatives. Organic letters 20110415
Design, synthesis, and evaluation of small molecule Hsp90 probes. Bioorganic & medicinal chemistry 20110415
Coumarin-purine ribofuranoside conjugates as new agents against hepatitis C virus. Journal of medicinal chemistry 20110414
Structure of mammalian AMPK and its regulation by ADP. Nature 20110414
Effects of Mg2+ on the free energy landscape for folding a purine riboswitch RNA. Biochemistry 20110412
Phenotypes and circadian rhythm in utilization of formate in purine nucleotide biosynthesis de novo in adult humans. Life sciences 20110411
Fabrication of a bilayer potentiometric phosphate biosensor by cross-link immobilization with bovine serum albumin and glutaraldehyde. Analytica chimica acta 20110408
7-Deazapurine biosynthesis: NMR study of toyocamycin biosynthesis in Streptomyces rimosus using 2-13C-7-15N-adenine. Organic & biomolecular chemistry 20110407
Computational design of ring-expanded pyrimidine-based DNA motifs with improved conductivity. Physical chemistry chemical physics : PCCP 20110407
Microwave promoted C6-alkylation of purines through S(N)Ar-based reaction of 6-chloropurines with 3-alkyl-acetylacetone. Organic & biomolecular chemistry 20110407
Arsenate and phosphate as nucleophiles at the transition states of human purine nucleoside phosphorylase. Biochemistry 20110405
Pentostatin for treatment of steroid-refractory acute GVHD: a retrospective single-center analysis. Bone marrow transplantation 20110401
Proper laboratory notebook practices: protecting your intellectual property. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20110401
Pyruvate: immunonutritional effects on neutrophil intracellular amino or alpha-keto acid profiles and reactive oxygen species production. Amino acids 20110401
Biochemical characterization of the Mycobacterium tuberculosis phosphoribosyl-1-pyrophosphate synthetase. Glycobiology 20110401
Human biodistribution and radiation dosimetry of novel PET probes targeting the deoxyribonucleoside salvage pathway. European journal of nuclear medicine and molecular imaging 20110401
Identification of nuclear genes encoding chloroplast-localized proteins required for embryo development in Arabidopsis. Plant physiology 20110401
Breast fine-needle aspiration malondialdehyde deoxyguanosine adduct in breast cancer. Free radical research 20110401
Metabolomic anatomy of an animal model revealing homeostatic imbalances in dyslipidaemia. Molecular bioSystems 20110401
The A2a adenosine receptor modulates the reinforcement efficacy and neurotoxicity of MDMA. Journal of psychopharmacology (Oxford, England) 20110401
Deconstructing tick saliva: non-protein molecules with potent immunomodulatory properties. The Journal of biological chemistry 20110401
Role of insert-1 of myosin VI in modulating nucleotide affinity. The Journal of biological chemistry 20110401
Spectroscopy study on the noncovalent interactions in the binary and ternary systems of L-lysine, adenosine 5'-triphosphate and magnesium ions. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110401
Photosensitizer-doped conjugated polymer nanoparticles with high cross-sections for one- and two-photon excitation. Nanoscale 20110401
Recombinant Escherichia coli GMP reductase: kinetic, catalytic and chemical mechanisms, and thermodynamics of enzyme-ligand binary complex formation. Molecular bioSystems 20110401
Targeting tumors that lack methylthioadenosine phosphorylase (MTAP) activity: current strategies. Cancer biology & therapy 20110401
Purinergic signaling in neural development. Seminars in cell & developmental biology 20110401
Neuroglial interactions mediated by purinergic signalling in the pathophysiology of CNS disorders. Seminars in cell & developmental biology 20110401
Dynamic metabonomic responses of tobacco (Nicotiana tabacum) plants to salt stress. Journal of proteome research 20110401
Synthesis of purin-2-yl and purin-6-yl-aminoglucitols as C-nucleosidic ATP mimics and biological evaluation as FGFR3 inhibitors. European journal of medicinal chemistry 20110401
Enzymatic activity of the soybean ecto-apyrase GS52 is essential for stimulation of nodulation. Plant physiology 20110401
Hyperuricemia as a mediator of the proinflammatory endocrine imbalance in the adipose tissue in a murine model of the metabolic syndrome. Diabetes 20110401
ATP: a ubiquitous gliotransmitter integrating neuron-glial networks. Seminars in cell & developmental biology 20110401
The role of extracellular adenosine in chemical neurotransmission in the hippocampus and Basal Ganglia: pharmacological and clinical aspects. Current topics in medicinal chemistry 20110401
Nitrogen partitioning and isotopic fractionation in dairy cows consuming diets based on a range of contrasting forages. Journal of dairy science 20110401
Synthesis and antiviral activity of N9-[3-fluoro-2-(phosphonomethoxy)propyl] analogues derived from N6-substituted adenines and 2,6-diaminopurines. Bioorganic & medicinal chemistry 20110401
Simultaneous determination of 5'-monophosphate nucleotides in infant formulas by HPLC-MS. Journal of chromatographic science 20110401
The complete chloroplast genome of 17 individuals of pest species Jacobaea vulgaris: SNPs, microsatellites and barcoding markers for population and phylogenetic studies. DNA research : an international journal for rapid publication of reports on genes and genomes 20110401
[Autoimmune haemolytic anemia: diagnosis strategy and new treatments]. Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine 20110401
Formation of nucleobases from formamide in the presence of iron oxides: implication in chemical evolution and origin of life. Astrobiology 20110401
Deep UV resonant Raman spectroscopy for photodamage characterization in cells. Biomedical optics express 20110401
Characterization of schistosome tegumental alkaline phosphatase (SmAP). PLoS neglected tropical diseases 20110401
High throughput screens yield small molecule inhibitors of Leishmania CRK3:CYC6 cyclin-dependent kinase. PLoS neglected tropical diseases 20110401
Intermolecular interaction between a branching ribozyme and associated homing endonuclease mRNA. Biological chemistry 20110401
In silico elucidation of the recognition dynamics of ubiquitin. PLoS computational biology 20110401
Fluctuations in spo0A transcription control rare developmental transitions in Bacillus subtilis. PLoS genetics 20110401
Metabolism of microbial nitrogen in ruminants with special reference to nucleic acids. Animal science journal = Nihon chikusan Gakkaiho 20110401
Changes in Adenosine Deaminase Activity in Patients with Type 2 Diabetes Mellitus and Effect of DPP-4 Inhibitor Treatment on ADA Activity. Diabetes & metabolism journal 20110401
[The role of uric acid in heart failure]. Revista medica de Chile 20110401
Effects of low dose methotrexate on relapsing-remitting multiple sclerosis in comparison to Interferon β-1α: A randomized controlled trial. Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110401
In situ evaluation of anticancer drug methotrexate-DNA interaction using a DNA-electrochemical biosensor and AFM characterization. Physical chemistry chemical physics : PCCP 20110328
New synthetic triterpenoids: potent agents for prevention and treatment of tissue injury caused by inflammatory and oxidative stress. Journal of natural products 20110325
Novel ligands for a purine riboswitch discovered by RNA-ligand docking. Chemistry & biology 20110325
Xanthine dehydrogenase electrocatalysis: autocatalysis and novel activity. The journal of physical chemistry. B 20110324
Nucleoside transport inhibitors: structure-activity relationships for pyrimido[5,4-d]pyrimidine derivatives that potentiate pemetrexed cytotoxicity in the presence of α1-acid glycoprotein. Journal of medicinal chemistry 20110324
Substitution of active site tyrosines with tryptophan alters the free energy for nucleotide flipping by human alkyladenine DNA glycosylase. Biochemistry 20110322
A high-affinity adenosine kinase from Anopheles gambiae. Biochemistry 20110322
Metabolic fate of fumarate, a side product of the purine salvage pathway in the intraerythrocytic stages of Plasmodium falciparum. The Journal of biological chemistry 20110318
Simultaneous detection of guanine, adenine, thymine and cytosine at choline monolayer supported multiwalled carbon nanotubes film. Biosensors & bioelectronics 20110315
Shmt1 heterozygosity impairs folate-dependent thymidylate synthesis capacity and modifies risk of Apc(min)-mediated intestinal cancer risk. Cancer research 20110315
Development of modified nucleosides that have supremely high anti-HIV activity and low toxicity and prevent the emergence of resistant HIV mutants. Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110311
Tail-labelling of DNA probes using modified deoxynucleotide triphosphates and terminal deoxynucleotidyl transferase. Application in electrochemical DNA hybridization and protein-DNA binding assays. Organic & biomolecular chemistry 20110307
Observation of the reversibility of a covalent pyrrolobenzodiazepine (PBD) DNA adduct by HPLC/MS and CD spectroscopy. Organic & biomolecular chemistry 20110307
Comprehensive proteomic analysis of the effects of purine analogs on human Raji B-cell lymphoma. Journal of proteome research 20110304
Gcn4p-mediated transcriptional repression of ribosomal protein genes under amino-acid starvation. The EMBO journal 20110302
Allopurinol and xanthine oxidase inhibition in liver ischemia reperfusion. Journal of hepato-biliary-pancreatic sciences 20110301
Initiation of translation at an upstream non-AUG codon accounting for N-terminally extended minor forms of recombinant proteins expressed in insect cells. Protein expression and purification 20110301
In vivo methods to study uptake of nanoparticles into the brain. Pharmaceutical research 20110301
Modulation of circulating purines and pyrimidines by physical exercise in the horse. European journal of applied physiology 20110301
DNA strand breaks and base modifications induced by cholesterol hydroperoxides. Free radical research 20110301
Purification, characterization, and cloning of a bifunctional molybdoenzyme with hydratase and alcohol dehydrogenase activity. Applied microbiology and biotechnology 20110301
Nucleoside analogs induce proteasomal down-regulation of p21 in chronic lymphocytic leukemia cell lines. Biochemical pharmacology 20110301
Gout and hyperuricemia in young people. Current opinion in rheumatology 20110301
Germline copy number variations in BRCA1-associated ovarian cancer patients. Genes, chromosomes & cancer 20110301
Purine 5',8-cyclonucleoside lesions: chemistry and biology. Chemical Society reviews 20110301
Characterization of the B6.61 polymerase ribozyme accessory domain. RNA (New York, N.Y.) 20110301
Strict 3' splice site sequence requirements for U2 snRNP recruitment after U2AF binding underlie a genetic defect leading to autoimmune disease. RNA (New York, N.Y.) 20110301
Identification of a chemical that inhibits the mycobacterial UvrABC complex in nucleotide excision repair. Biochemistry 20110301
Arabidopsis nucleoside hydrolases involved in intracellular and extracellular degradation of purines. The Plant journal : for cell and molecular biology 20110301
Deoxycytidine kinase modulates the impact of the ABC transporter ABCG2 on clofarabine cytotoxicity. Cancer research 20110301
Enhanced expression of recX in Mycobacterium tuberculosis owing to a promoter internal to recA. Tuberculosis (Edinburgh, Scotland) 20110301
Hijacking a biosynthetic pathway yields a glycosyltransferase inhibitor within cells. Nature chemical biology 20110301
Increased sensitivity to thiopurines in methylthioadenosine phosphorylase-deleted cancers. Molecular cancer therapeutics 20110301
New nucleoside analogs for patients with hematological malignancies. Expert opinion on investigational drugs 20110301
Optimal pharmacotherapeutic management of chronic lymphocytic leukaemia: considerations in the elderly. Drugs & aging 20110301
Febuxostat for treatment of chronic gout. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20110301
The effect of the feed-to-buffer ratio on bacterial diversity and ruminal fermentation in single-flow continuous-culture fermenters. Journal of dairy science 20110301
Interleukin-21 is critically required in autoimmune and allogeneic responses to islet tissue in murine models. Diabetes 20110301
Clinical presentation and pathogenesis of cold-induced autoinflammatory disease in a family with recurrence of an NLRP12 mutation. Arthritis and rheumatism 20110301
The effects of intraoperative adenosine infusion on acute opioid tolerance and opioid induced hyperalgesia induced by remifentanil in adult patients undergoing tonsillectomy. The Korean journal of pain 20110301
The relationship between normal serum uric acid and nonalcoholic fatty liver disease. Journal of Korean medical science 20110301
Urea metabolism in plants. Plant science : an international journal of experimental plant biology 20110301
The Staphylococcus aureus RNome and its commitment to virulence. PLoS pathogens 20110301
Towards personalized medicine - the role of methotrexate. The Indian journal of medical research 20110301
Profiling single nucleotide polymorphisms (SNPs) across intracellular folate metabolic pathway in healthy Indians. The Indian journal of medical research 20110301
A novel mechanism of programmed cell death in bacteria by toxin-antitoxin systems corrupts peptidoglycan synthesis. PLoS biology 20110301
Consensus-phenotype integration of transcriptomic and metabolomic data implies a role for metabolism in the chemosensitivity of tumour cells. PLoS computational biology 20110301
Reconciliation of genome-scale metabolic reconstructions for comparative systems analysis. PLoS computational biology 20110301
The Toll-like receptor gene family is integrated into human DNA damage and p53 networks. PLoS genetics 20110301
Second annual UK Purine Club Symposium report 2010. Purinergic signalling 20110301
UK Purine Club 2010 Abstracts. Purinergic signalling 20110301
6-Chloro-9-(2-nitro-phenyl-sulfon-yl)-9H-purine. Acta crystallographica. Section E, Structure reports online 20110301
Differential gene expression in the nucleus accumbens and frontal cortex of lewis and Fischer 344 rats relevant to drug addiction. Current neuropharmacology 20110301
Role of ribose deficit in rat testicular metabolism under conditions of overtraining. Bulletin of experimental biology and medicine 20110301
Guidelines for the management of bacterial and fungal infections during chemotherapy for pediatric acute leukemia or solid tumors: what is available in 2010? Pediatric reports 20110224
Methylthioinosine phosphorylase from Pseudomonas aeruginosa. Structure and annotation of a novel enzyme in quorum sensing. Biochemistry 20110222
Trifunctionalization of the purine scaffold using Mg and Zn organometallic intermediates. Organic letters 20110218
Determination of uric acid and creatinine in human urine using hydrophilic interaction chromatography. Talanta 20110215
Modern strategies for hairy cell leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110210
Ionization of purine tautomers in nucleobases, nucleosides, and nucleotides: from the gas phase to the aqueous environment. The journal of physical chemistry. B 20110210
Chemical shift tensors in isomers of adenine: relation to aromaticity of purine rings? Chemphyschem : a European journal of chemical physics and physical chemistry 20110207
Recognition of transcription termination signal by the nuclear polyadenylated RNA-binding (NAB) 3 protein. The Journal of biological chemistry 20110204
Energetically important C-H···F-C pseudohydrogen bonding in water: evidence and application to rational design of oligonucleotides with high binding affinity. Journal of the American Chemical Society 20110202
Hairy-cell leukemia variant: recent view on diagnosis, biology and treatment. Cancer treatment reviews 20110201
Prognostic value of xanthine oxidoreductase expression in patients with non-small cell lung cancer. Lung cancer (Amsterdam, Netherlands) 20110201
Resveratrol increases rate of apoptosis caused by purine analogues in malignant lymphocytes of chronic lymphocytic leukemia. Annals of hematology 20110201
β-nicotinamide adenine dinucleotide is an enteric inhibitory neurotransmitter in human and nonhuman primate colons. Gastroenterology 20110201
Endogenous fraction and urinary recovery of purine derivatives obtained by different methods in Nellore cattle. Journal of animal science 20110201
Purine analog for the prevention of postoperative recurrence of Crohn's disease: is it really better? Inflammatory bowel diseases 20110201
Characterization of a broad-specificity non-haem iron N-demethylase from Pseudomonas putida CBB5 capable of utilizing several purine alkaloids as sole carbon and nitrogen source. Microbiology (Reading, England) 20110201
The hydrolysis of striatal adenine- and guanine-based purines in a 6-hydroxydopamine rat model of Parkinson's disease. Neurochemical research 20110201
Purine receptor-mediated endocannabinoid production and retrograde synaptic signalling in the cerebellar cortex. British journal of pharmacology 20110201
Cladribine combined with rituximab (R-2-CdA) therapy is an effective salvage therapy in relapsed or refractory indolent B-cell non-Hodgkin lymphoma. European journal of haematology 20110201
Dietary effects on body composition, glucose metabolism, and longevity are modulated by skeletal muscle mitochondrial uncoupling in mice. Aging cell 20110201
The GB viruses: a review and proposed classification of GBV-A, GBV-C (HGV), and GBV-D in genus Pegivirus within the family Flaviviridae. The Journal of general virology 20110201
Effects of molybdenum deficiency and defects in molybdate transporter MOT1 on transcript accumulation and nitrogen/sulphur metabolism in Arabidopsis thaliana. Journal of experimental botany 20110201
Plasticity in the purine-thiamine metabolic network of Salmonella. Genetics 20110201
Urinary stone composition in pediatric patients: a retrospective study of 205 cases. Clinical chemistry and laboratory medicine 20110201
Reactivation of meristem activity and sprout growth in potato tubers require both cytokinin and gibberellin. Plant physiology 20110201
Results of a phase II study of pemetrexed as first-line chemotherapy in patients with advanced or metastatic breast cancer. Breast cancer research and treatment 20110201
Glutamine triggers and potentiates glucagon-like peptide-1 secretion by raising cytosolic Ca2+ and cAMP. Endocrinology 20110201
Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell. EMBO molecular medicine 20110201
Hairy cell leukemia and variant in Taiwan: report of a variant case and literature review. International journal of clinical and experimental pathology 20110201
Adenosine modulates Toll-like receptor function: basic mechanisms and translational opportunities. Expert review of anti-infective therapy 20110201
[A case of chronic myeloid leukemia occurring during treatment for chronic lymphocytic leukemia]. Gan to kagaku ryoho. Cancer & chemotherapy 20110201
Deoxycytidine production by metabolically engineered Corynebacterium ammoniagenes. Journal of microbiology (Seoul, Korea) 20110201
Dynamically-driven inactivation of the catalytic machinery of the SARS 3C-like protease by the N214A mutation on the extra domain. PLoS computational biology 20110201
p73 as a pharmaceutical target for cancer therapy. Current pharmaceutical design 20110201
Adeninium perchlorate. Acta crystallographica. Section E, Structure reports online 20110201
1-{4-Chloro-2-[2-(2-fluoro-phen-yl)-1,3-dithio-lan-2-yl]phen-yl}-2-methyl-1H-imidazole-5-carbaldehyde. Acta crystallographica. Section E, Structure reports online 20110201
Metabolomics as a powerful tool for molecular quality assessment of the fish Sparus aurata. Nutrients 20110201
Genotoxic evaluation of the non-halogenated disinfection by-products nitrosodimethylamine and nitrosodiethylamine. Journal of hazardous materials 20110130
A feedback circuit between transcriptional activation and self-destruction of Gcn4 separates its metabolic and morphogenic response in diploid yeasts. Journal of molecular biology 20110128
Kinetic and chemical mechanism of the dihydrofolate reductase from Mycobacterium tuberculosis. Biochemistry 20110125
Active-site structure of class IV adenylyl cyclase and transphyletic mechanism. Journal of molecular biology 20110121
Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease. The Cochrane database of systematic reviews 20110119
UMP kinase from Mycobacterium tuberculosis: Mode of action and allosteric interactions, and their likely role in pyrimidine metabolism regulation. Archives of biochemistry and biophysics 20110115
The dynamics of single spike-evoked adenosine release in the cerebellum. The Journal of physiology 20110115
Identifying cancer driver genes in tumor genome sequencing studies. Bioinformatics (Oxford, England) 20110115
Discovery of a series of phosphonic acid-containing thiazoles and orally bioavailable diamide prodrugs that lower glucose in diabetic animals through inhibition of fructose-1,6-bisphosphatase. Journal of medicinal chemistry 20110113
Investigations into the origin of the molecular recognition of several adenosine deaminase inhibitors. Journal of medicinal chemistry 20110113
Computational biology for ageing. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20110112
Evidence for a near-resonant charge transfer mechanism for double-stranded peptide nucleic acid. Journal of the American Chemical Society 20110112
[Effect of dantrolene on energy metabolism in rats with myocardial ischemia-reperfusion]. Zhonghua yi xue za zhi 20110111
Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: a C2'endo/syn 'southern' ribose conformation underlies activity at the sea urchin cADPR receptor. Organic & biomolecular chemistry 20110107
Functional gene expression profiling in yeast implicates translational dysfunction in mutant huntingtin toxicity. The Journal of biological chemistry 20110107
Regulation of ENT1 expression and ENT1-dependent nucleoside transport by c-Jun N-terminal kinase. Biochemical and biophysical research communications 20110107
Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma. British journal of cancer 20110104
Purinergic activation of dorsal root ganglion neurones in vivo. Neuroscience letters 20110103
N-methylpurines are heterogeneously repaired in human mitochondria but not evidently repaired in yeast mitochondria. DNA repair 20110102
A rapid and simple chemiluminescence method for screening levels of inosine and hypoxanthine in non-traumatic chest pain patients. Luminescence : the journal of biological and chemical luminescence 20110101
The use of tropical protein-rich leaves as supplements to Thai swamp buffalo receiving a basal diet of rice straw and treated leucaena (Leucaena leucocephala). Tropical animal health and production 20110101
A Bayesian approach for fast and accurate gene tree reconstruction. Molecular biology and evolution 20110101
Ubiquinol (QH(2)) functions as a negative regulator of purine nucleotide inhibition of Acanthamoeba castellanii mitochondrial uncoupling protein. Biochimica et biophysica acta 20110101
Enhancement of extracellular purine nucleoside accumulation by Bacillus strains through genetic modifications of genes involved in nucleoside export. Journal of industrial microbiology & biotechnology 20110101
Distribution, biosynthesis and catabolism of methylxanthines in plants. Handbook of experimental pharmacology 20110101
Inhibition of cyclic nucleotide phosphodiesterases by methylxanthines and related compounds. Handbook of experimental pharmacology 20110101
Evidence of feminization in wild Elliptio complanata mussels in the receiving waters downstream of a municipal effluent outfall. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110101
Molecular characterization of the AdeI mutant of Chinese hamster ovary cells: a cellular model of adenylosuccinate lyase deficiency. Molecular genetics and metabolism 20110101
Dur3 is the major urea transporter in Candida albicans and is co-regulated with the urea amidolyase Dur1,2. Microbiology (Reading, England) 20110101
Characterization of amplicons that suppress the conditional lethal growth phenotype of a Leishmania donovani mutant lacking normal purine salvage mechanisms. Molecular and biochemical parasitology 20110101
A systematic review of factors that contribute to hepatosplenic T-cell lymphoma in patients with inflammatory bowel disease. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20110101
Brassinolide-improved development of Brassica napus microspore-derived embryos is associated with increased activities of purine and pyrimidine salvage pathways. Planta 20110101
Interaction of the diguanylate cyclase YdeH of Escherichia coli with 2',(3')-substituted purine and pyrimidine nucleotides. The Journal of pharmacology and experimental therapeutics 20110101
Biological Evaluation of Polyherbal Ayurvedic Cardiotonic Preparation 'Mahamrutyunjaya rasa'. Evidence-based complementary and alternative medicine : eCAM 20110101
The effect of genotype on methotrexate polyglutamate variability in juvenile idiopathic arthritis and association with drug response. Arthritis and rheumatism 20110101
The Role of Allogeneic Stem Cell Transplantation in Relapsed/Refractory Hodgkin's Lymphoma Patients. Advances in hematology 20110101
Rationale for possible targeting of histone deacetylase signaling in cancer diseases with a special reference to pancreatic cancer. Journal of biomedicine & biotechnology 20110101
Genetic association mapping identifies single nucleotide polymorphisms in genes that affect abscisic acid levels in maize floral tissues during drought. Journal of experimental botany 20110101
Comparative proteomic and genetic analyses reveal unidentified mutations in Escherichia coli XL1-Blue and DH5α. FEMS microbiology letters 20110101
A population study of Lesch-Nyhan disease in the UK. Developmental medicine and child neurology 20110101
Phosphoramidate pronucleotides of cytostatic 6-aryl-7-deazapurine ribonucleosides. Bioorganic & medicinal chemistry 20110101
The role of system-specific molecular chaperones in the maturation of molybdoenzymes in bacteria. Biochemistry research international 20110101
Relative similarity within purine nucleotide and ligand structures operating on nitric oxide synthetase, guanylyl cyclase and potassium (K ATP, BK Ca) channels. The Journal of pharmacy and pharmacology 20110101
Purine nucleoside phosphorylase from Schistosoma mansoni in complex with ribose-1-phosphate. Journal of synchrotron radiation 20110101
Geometric properties of nucleic acids with potential for autobuilding. Acta crystallographica. Section A, Foundations of crystallography 20110101
R2R--software to speed the depiction of aesthetic consensus RNA secondary structures. BMC bioinformatics 20110101
HPLC analysis for the clinical-biochemical diagnosis of inborn errors of metabolism of purines and pyrimidines. Methods in molecular biology (Clifton, N.J.) 20110101
Impact of Alu repeats on the evolution of human p53 binding sites. Biology direct 20110101
The substrate binding preferences of Plasmodium thymidylate kinase. Biological & pharmaceutical bulletin 20110101
Antimicrobial and antineoplastic activities of agelasine analogs modified in the purine 2-position. Archiv der Pharmazie 20110101
Metabolic pathway engineering based on metabolomics confers acetic and formic acid tolerance to a recombinant xylose-fermenting strain of Saccharomyces cerevisiae. Microbial cell factories 20110101
A proteomic analysis of C-reactive protein stimulated THP-1 monocytes. Proteome science 20110101
Implementation of a new cost efficacy method for blood irradiation using a non dedicated device. Journal of experimental & clinical cancer research : CR 20110101
Uptake of AMP, ADP, and ATP in Escherichia coli W. Bioscience, biotechnology, and biochemistry 20110101
Blood lipid profiles and peripheral blood mononuclear cell cholesterol metabolism gene expression in patients with and without methotrexate treatment. BMC medicine 20110101
Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets? International journal of biological sciences 20110101
Mitochondrial dysfunction in Parkinson's disease: pathogenesis and neuroprotection. Parkinson's disease 20110101
Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors. Silence 20110101
Gadd45a is an RNA binding protein and is localized in nuclear speckles. PloS one 20110101
Liposarcoma: molecular genetics and therapeutics. Sarcoma 20110101
Effector granules in human T lymphocytes: the luminal proteome of secretory lysosomes from human T cells. Cell communication and signaling : CCS 20110101
Small RNAs in the genus Clostridium. mBio 20110101
Removal of PCR error products and unincorporated primers by metal-chelate affinity chromatography. PloS one 20110101
Distinctive mitochondrial genome of Calanoid copepod Calanus sinicus with multiple large non-coding regions and reshuffled gene order: useful molecular markers for phylogenetic and population studies. BMC genomics 20110101
Uric acid as a predictor of all-cause mortality in heart failure: a meta-analysis. Congestive heart failure (Greenwich, Conn.) 20110101
Label-free peptide profiling of Orbitrap™ full mass spectra. BMC research notes 20110101
Metabolomic profiling for identification of novel potential biomarkers in cardiovascular diseases. Journal of biomedicine & biotechnology 20110101
Evolution of major milk proteins in Mus musculus and Mus spretus mouse species: a genoproteomic analysis. BMC genomics 20110101
Flux balance analysis of ammonia assimilation network in E. coli predicts preferred regulation point. PloS one 20110101
It takes two to tango: defining an essential second active site in pyridoxal 5'-phosphate synthase. PloS one 20110101
Transcriptomic signatures of ash (Fraxinus spp.) phloem. PloS one 20110101
Comparative study between transcriptionally- and translationally-acting adenine riboswitches reveals key differences in riboswitch regulatory mechanisms. PLoS genetics 20110101
Exploiting Statistical Methodologies and Controlled Vocabularies for Prioritized Functional Analysis of Genomic Experiments: the StRAnGER Web Application. Frontiers in neuroscience 20110101
A genome-wide association study of serum uric acid in African Americans. BMC medical genomics 20110101
Hypoxic regulation of glycosylation via the N-acetylglucosamine cycle. Journal of clinical biochemistry and nutrition 20110101
Nucleotides function as endogenous chemical sensors for oxidative stress signaling. Journal of clinical biochemistry and nutrition 20110101
Reduction in antioxidant enzyme expression and sustained inflammation enhance tissue damage in the subacute phase of spinal cord contusive injury. Journal of biomedical science 20110101
FCR (Fludarabine, Cyclophosphamide, Rituximab) regimen followed by 90Yttrium ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma: a report of 9 cases. Journal of experimental & clinical cancer research : CR 20110101
[The first case of adenine phosphoribosyltransferase deficiency with APRT Q0 (M1V) mutation in Japan]. Hinyokika kiyo. Acta urologica Japonica 20110101
Bacillus subtilis two-component system sensory kinase DegS is regulated by serine phosphorylation in its input domain. PloS one 20110101
Simple structural differences between coding and noncoding DNA. PloS one 20110101
Inaccurate DNA synthesis in cell extracts of yeast producing active human DNA polymerase iota. PloS one 20110101
HPRT deficiency coordinately dysregulates canonical Wnt and presenilin-1 signaling: a neuro-developmental regulatory role for a housekeeping gene? PloS one 20110101
Genomic organization and splicing evolution of the doublesex gene, a Drosophila regulator of sexual differentiation, in the dengue and yellow fever mosquito Aedes aegypti. BMC evolutionary biology 20110101
Challenges of ligand identification for riboswitch candidates. RNA biology 20110101
Lysyl oxidase, a critical intra- and extra-cellular target in the lung for cigarette smoke pathogenesis. International journal of environmental research and public health 20110101
Potential of immunosuppressive agents in cerebral ischaemia. The Indian journal of medical research 20110101
Staphylococcus aureus seroproteomes discriminate ruminant isolates causing mild or severe mastitis. Veterinary research 20110101
Proteome analyses of cellular proteins in methicillin-resistant Staphylococcus aureus treated with rhodomyrtone, a novel antibiotic candidate. PloS one 20110101
SOD2 deficient erythroid cells up-regulate transferrin receptor and down-regulate mitochondrial biogenesis and metabolism. PloS one 20110101
Effect of attC structure on cassette excision by integron integrases. Mobile DNA 20110101
Simulated evolution applied to study the genetic code optimality using a model of codon reassignments. BMC bioinformatics 20110101
Minor contribution of ATP P2 receptors to electrically-evoked electrographic seizure activity in hippocampal slices: Evidence from purine biosensors and P2 receptor agonists and antagonists. Neuropharmacology 20110101
Role of rituximab in first-line treatment of chronic lymphocytic leukemia. Therapeutics and clinical risk management 20110101
On origin of genetic code and tRNA before translation. Biology direct 20110101
The G protein-coupled receptors in the pufferfish Takifugu rubripes. BMC bioinformatics 20110101
iGEMDOCK: a graphical environment of enhancing GEMDOCK using pharmacological interactions and post-screening analysis. BMC bioinformatics 20110101
Unfolded protein response in cancer: the physician's perspective. Journal of hematology & oncology 20110101
Alanine zipper-like coiled-coil domains are necessary for homotypic dimerization of plant GAGA-factors in the nucleus and nucleolus. PloS one 20110101
Molecular biology of the blood-brain and the blood-cerebrospinal fluid barriers: similarities and differences. Fluids and barriers of the CNS 20110101
Complementary effects of extracellular nucleotides and platelet-derived extracts on angiogenesis of vasa vasorum endothelial cells in vitro and subcutaneous Matrigel plugs in vivo. Vascular cell 20110101
Multi-omics approach to study the growth efficiency and amino acid metabolism in Lactococcus lactis at various specific growth rates. Microbial cell factories 20110101
Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds. BMC genomics 20110101
Gene expression throughout a vertebrate's embryogenesis. BMC genomics 20110101
Bacillus anthracis spore interactions with mammalian cells: relationship between germination state and the outcome of in vitro. BMC microbiology 20110101
The human serum metabolome. PloS one 20110101
High throughput nano-liter RT-qPCR to classify soil contamination using a soil arthropod. BMC molecular biology 20110101
Multiple invasions into freshwater by pufferfishes (teleostei: tetraodontidae): a mitogenomic perspective. PloS one 20110101
Molecular dynamics simulations of protein targets identified in Mycobacterium tuberculosis. Current medicinal chemistry 20110101
Purine Salvage Pathway in Mycobacterium tuberculosis. Current medicinal chemistry 20110101
Novel sulI binary vectors enable an inexpensive foliar selection method in Arabidopsis. BMC research notes 20110101
Bioinformatics analysis of disordered proteins in prokaryotes. BMC bioinformatics 20110101
Alternative TFAP2A isoforms have distinct activities in breast cancer. Breast cancer research : BCR 20110101
[Preliminary study on molecular mechanism of lotus mutants induced by ion implantation]. Yi chuan = Hereditas 20110101
Antiproliferative property of hexadecyloxypropyl 9-[2-(phosphonomethoxy) ethyl] guanine (HDP-PMEG) for unwanted ocular proliferation. Molecular vision 20110101
New implications on genomic adaptation derived from the Helicobacter pylori genome comparison. PloS one 20110101
The PI3K p110δ regulates expression of CD38 on regulatory T cells. PloS one 20110101
Molecular biology of nucleoside transporters and their distributions and functions in the brain. Current topics in medicinal chemistry 20110101
Neurological disorders of purine and pyrimidine metabolism. Current topics in medicinal chemistry 20110101
Metabolic network of nucleosides in the brain. Current topics in medicinal chemistry 20110101
Genome wide SNP discovery, analysis and evaluation in mallard (Anas platyrhynchos). BMC genomics 20110101
Sequential analysis of global gene expression profiles in immature and in vitro matured bovine oocytes: potential molecular markers of oocyte maturation. BMC genomics 20110101
Cyclosporine A for chemotherapy-resistant subcutaneous panniculitis-like T cell lymphoma with hemophagocytic syndrome. Acta haematologica 20110101
Expression of Drosophila adenosine deaminase in immune cells during inflammatory response. PloS one 20110101
Modeling antibiotic and cytotoxic effects of the dimeric isoquinoline IQ-143 on metabolism and its regulation in Staphylococcus aureus, Staphylococcus epidermidis and human cells. Genome biology 20110101
Across bacterial phyla, distantly-related genomes with similar genomic GC content have similar patterns of amino acid usage. PloS one 20110101
The importance of alkynyl chain presence for the activity of adenine nucleosides/nucleotides on purinergic receptors. Current medicinal chemistry 20110101
Tegument protein control of latent herpesvirus establishment and animation. Herpesviridae 20110101
Importance of phenols structure on their activity as antinitrosating agents: A kinetic study. Journal of pharmacy & bioallied sciences 20110101
One function--multiple mechanisms: the manifold activities of p53 as a transcriptional repressor. Journal of biomedicine & biotechnology 20110101
Proteomic definitions of mesenchymal stem cells. Stem cells international 20110101
Endophyte microbiome diversity in micropropagated Atriplex canescens and Atriplex torreyi var griffithsii. PloS one 20110101
Interpreting linear support vector machine models with heat map molecule coloring. Journal of cheminformatics 20110101
The self-organizing fractal theory as a universal discovery method: the phenomenon of life. Theoretical biology & medical modelling 20110101
Metabolites of purine nucleoside phosphorylase (NP) in serum have the potential to delineate pancreatic adenocarcinoma. PloS one 20110101
Patient considerations in the management of multiple sclerosis: development and clinical utility of oral agents. Patient preference and adherence 20110101
A study protocol for the evaluation of occupational mutagenic/carcinogenic risks in subjects exposed to antineoplastic drugs: a multicentric project. BMC public health 20110101
Shotgun sequencing of Yersinia enterocolitica strain W22703 (biotype 2, serotype O:9): genomic evidence for oscillation between invertebrates and mammals. BMC genomics 20110101
Downstream molecular pathways of FLT3 in the pathogenesis of acute myeloid leukemia: biology and therapeutic implications. Journal of hematology & oncology 20110101
An illustrative case of subcutaneous panniculitis-like T-cell lymphoma. Journal of skin cancer 20110101
Exploring uncoupling proteins and antioxidant mechanisms under acute cold exposure in brains of fish. PloS one 20110101
Ticagrelor: the evidence for its clinical potential as an oral antiplatelet treatment for the reduction of major adverse cardiac events in patients with acute coronary syndromes. Core evidence 20110101
Levels of certain tumor markers as differential factors between bilharzial and non-biharzial bladder cancer among Egyptian patients. Cancer cell international 20110101
Extranodal rosai-dorfman disease with cutaneous and periodontal involvement: a rare presentation. Case reports in oncology 20110101
Effect of a fat spread enriched with medium-chain triacylglycerols and a special fatty acid-micronutrient combination on cardiometabolic risk factors in overweight patients with diabetes. Nutrition & metabolism 20110101
Relevance of laboratory testing for the diagnosis of primary immunodeficiencies: a review of case-based examples of selected immunodeficiencies. Clinical and molecular allergy : CMA 20110101
Uremic toxins inhibit transport by breast cancer resistance protein and multidrug resistance protein 4 at clinically relevant concentrations. PloS one 20110101
The cyclophilin-binding agent Sanglifehrin A is a dendritic cell chemokine and migration inhibitor. PloS one 20110101
Comprehensive analysis of transcript start sites in ly49 genes reveals an unexpected relationship with gene function and a lack of upstream promoters. PloS one 20110101
Further improvements of the P. falciparum humanized mouse model. PloS one 20110101
FORS-D Analysis in P. falciparum can Differentiate Classes of Genes Under Selection. Evolutionary bioinformatics online 20110101
The emerging role of ofatumumab in the treatment of chronic lymphocytic leukemia. Clinical Medicine Insights. Oncology 20110101
Comparative genome sequence analysis underscores mycoparasitism as the ancestral life style of Trichoderma. Genome biology 20110101
Nucleosome DNA sequence structure of isochores. BMC genomics 20110101
Comparative analysis of expressed sequence tags (ESTs) between drought-tolerant and -susceptible genotypes of chickpea under terminal drought stress. BMC plant biology 20110101
Effect of vitamin E (Tri E®) on antioxidant enzymes and DNA damage in rats following eight weeks exercise. Nutrition journal 20110101
Advanced paternal age is a risk factor for schizophrenia in Iranians. Annals of general psychiatry 20110101
[Disorders of uric acid metabolism in rats with fructose-induced experimental insulin resistance syndrome]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20110101
2-Phenyl-7-(4-pyridyl-methyl-amino)-1,2,4-triazolo[1,5-a][1,3,5]triazin-5(4H)-one. Acta crystallographica. Section E, Structure reports online 20110101
Network modeling of the transcriptional effects of copy number aberrations in glioblastoma. Molecular systems biology 20110101
Co-crystal structures of PKG Iβ (92-227) with cGMP and cAMP reveal the molecular details of cyclic-nucleotide binding. PloS one 20110101
Host specific diversity in Lactobacillus johnsonii as evidenced by a major chromosomal inversion and phage resistance mechanisms. PloS one 20110101
Systems-scale analysis reveals pathways involved in cellular response to methamphetamine. PloS one 20110101
Evolution of an endofungal lifestyle: Deductions from the Burkholderia rhizoxinica genome. BMC genomics 20110101
Methotrexate toxicity in growing long bones of young rats: a model for studying cancer chemotherapy-induced bone growth defects in children. Journal of biomedicine & biotechnology 20110101
Homologous recombination is stimulated by a decrease in dUTPase in Arabidopsis. PloS one 20110101
Safety and efficacy of the immunosuppressive agent 6-tioguanine in murine model of acute and chronic colitis. BMC gastroenterology 20110101
A complicated case of tacrolimus-induced rapid remission after cesarean section in the early third trimester for refractory severe ulcerative colitis flaring in the initial period of gestation. Case reports in gastroenterology 20110101
The complete genome sequence of 'Candidatus Liberibacter solanacearum', the bacterium associated with potato zebra chip disease. PloS one 20110101
Absence of aquaporin-4 in skeletal muscle alters proteins involved in bioenergetic pathways and calcium handling. PloS one 20110101
More than 200 genes required for methane formation from H₂ and CO₂ and energy conservation are present in Methanothermobacter marburgensis and Methanothermobacter thermautotrophicus. Archaea (Vancouver, B.C.) 20110101
UMP/CMPK is not the critical enzyme in the metabolism of pyrimidine ribonucleotide and activation of deoxycytidine analogs in human RKO cells. PloS one 20110101
Localization of human RNase Z isoforms: dual nuclear/mitochondrial targeting of the ELAC2 gene product by alternative translation initiation. PloS one 20110101
Exploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features. PloS one 20110101
Regulation of airway nucleotides in chronic lung diseases. Sub-cellular biochemistry 20110101
[Diffuse large cell lymphoma and colon adenocarcinoma in patient with Waldenström's macroglobulinaemia]. Srpski arhiv za celokupno lekarstvo 20110101
Stimulation of growth of the human gastric pathogen Helicobacter pylori by atmospheric level of oxygen under high carbon dioxide tension. BMC microbiology 20110101
Functional specialization in nucleotide sugar transporters occurred through differentiation of the gene cluster EamA (DUF6) before the radiation of Viridiplantae. BMC evolutionary biology 20110101
Reduction in oxidatively generated DNA damage following smoking cessation. Tobacco induced diseases 20110101
Using next generation transcriptome sequencing to predict an ectomycorrhizal metabolome. BMC systems biology 20110101
Comparative proteomics analysis of proteins expressed in the I-1 and I-2 internodes of strawberry stolons. Proteome science 20110101
A case series of allopurinol-induced toxic epidermal necrolysis. Indian journal of dermatology 20110101
Complete genome sequence of Mycoplasma suis and insights into its biology and adaption to an erythrocyte niche. PloS one 20110101
Fur activates the expression of Salmonella enterica pathogenicity island 1 by directly interacting with the hilD operator in vivo and in vitro. PloS one 20110101
Treating ocular surface disease: new agents in development. Clinical ophthalmology (Auckland, N.Z.) 20110101
Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways. PloS one 20110101
Exploring metabolic pathway disruption in the subchronic phencyclidine model of schizophrenia with the Generalized Singular Value Decomposition. BMC systems biology 20110101
The importance of mitochondrial DNA in aging and cancer. Journal of aging research 20110101
[Deficiency of adenosine desaminase (ADA): clinical, biochemical, molecular and treatment aspects]. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20110101
Molecular characterization of Chinese hamster cells mutants affected in adenosine kinase and showing novel genetic and biochemical characteristics. BMC biochemistry 20110101
Supplementation of a western diet with golden kiwifruits (Actinidia chinensis var.'Hort 16A':) effects on biomarkers of oxidation damage and antioxidant protection. Nutrition journal 20110101
Pharmacology of purine and pyrimidine receptors. Preface. Advances in pharmacology (San Diego, Calif.) 20110101
Regulation of leukocyte function by adenosine receptors. Advances in pharmacology (San Diego, Calif.) 20110101
Allosteric modulation of purine and pyrimidine receptors. Advances in pharmacology (San Diego, Calif.) 20110101
Molecular mechanisms of purine and pyrimidine nucleotide release. Advances in pharmacology (San Diego, Calif.) 20110101
P2Y receptors in health and disease. Advances in pharmacology (San Diego, Calif.) 20110101
A motif unique to the human DEAD-box protein DDX3 is important for nucleic acid binding, ATP hydrolysis, RNA/DNA unwinding and HIV-1 replication. PloS one 20110101
Systematic and evolutionary insights derived from mtDNA COI barcode diversity in the Decapoda (Crustacea: Malacostraca). PloS one 20110101
Nrt1 and Tna1-independent export of NAD+ precursor vitamins promotes NAD+ homeostasis and allows engineering of vitamin production. PloS one 20110101
Host range, host specificity and hypothesized host shift events among viruses of lower vertebrates. Veterinary research 20110101
Transcriptome analysis by GeneTrail revealed regulation of functional categories in response to alterations of iron homeostasis in Arabidopsis thaliana. BMC plant biology 20110101
Spontaneous remission of Crohn's disease following a febrile infection: case report and literature review. BMC gastroenterology 20110101
Modeling microRNA-mRNA interactions using PLS regression in human colon cancer. BMC medical genomics 20110101
The enigmatic mitochondrial genome of Rhabdopleura compacta (Pterobranchia) reveals insights into selection of an efficient tRNA system and supports monophyly of Ambulacraria. BMC evolutionary biology 20110101
LeishVet guidelines for the practical management of canine leishmaniosis. Parasites & vectors 20110101
Possible roles of ectophosphatases in host-parasite interactions. Journal of parasitology research 20110101
Malaria Vaccine Development: Are Bacterial Flagellin Fusion Proteins the Bridge between Mouse and Humans? Journal of parasitology research 20110101
Alternative splicing of the human gene SYBL1 modulates protein domain architecture of Longin VAMP7/TI-VAMP, showing both non-SNARE and synaptobrevin-like isoforms. BMC molecular biology 20110101
Linear and non-linear dependencies between copy number aberrations and mRNA expression reveal distinct molecular pathways in breast cancer. BMC bioinformatics 20110101
The P2 receptor antagonist PPADS supports recovery from experimental stroke in vivo. PloS one 20110101
The proteomic complexity and rise of the primordial ancestor of diversified life. BMC evolutionary biology 20110101
A high resolution map of a cyanobacterial transcriptome. Genome biology 20110101
Construction of uricase-overproducing strains of Hansenula polymorpha and its application as biological recognition element in microbial urate biosensor. BMC biotechnology 20110101
Adhesive polypeptides of Staphylococcus aureus identified using a novel secretion library technique in Escherichia coli. BMC microbiology 20110101
Macromolecular bases of antischistosomal therapy. Current topics in medicinal chemistry 20110101
Purine and pyrimidine pathways as targets in Plasmodium falciparum. Current topics in medicinal chemistry 20110101
6-oxopurine phosphoribosyltransferase: a target for the development of antimalarial drugs. Current topics in medicinal chemistry 20110101
Path finding methods accounting for stoichiometry in metabolic networks. Genome biology 20110101
What are fungal infections? Mediterranean journal of hematology and infectious diseases 20110101
Development of oral immunomodulatory agents in the management of multiple sclerosis. Drug design, development and therapy 20110101
Identification of metabolites in the normal ovary and their transformation in primary and metastatic ovarian cancer. PloS one 20110101
Systematic exploitation of multiple receptor conformations for virtual ligand screening. PloS one 20110101
Comparative transcriptome analysis of Bacillus subtilis responding to dissolved oxygen in adenosine fermentation. PloS one 20110101
Novel ocular antihypertensive compounds in clinical trials. Clinical ophthalmology (Auckland, N.Z.) 20110101
Adenosine A(2A) Receptor and IL-10 in Peripheral Blood Mononuclear Cells of Patients with Mild Cognitive Impairment. International journal of Alzheimer's disease 20110101
Tophaceous gout and renal insufficiency: a new solution for an old therapeutic dilemma. Case reports in medicine 20110101
Neutralising antibodies against ricin toxin. PloS one 20110101
Assessment of the genetic risks of a metallic alloy used in medical implants. Genetics and molecular biology 20110101
The hexameric structures of human heat shock protein 90. PloS one 20110101
Adenosine in the inflamed gut: a Janus faced compound. Current medicinal chemistry 20110101
The metabolic advantage of tumor cells. Molecular cancer 20110101
Identification of maturation and protein synthesis related proteins from porcine oocytes during in vitro maturation. Proteome science 20110101
Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity. Nutrition & metabolism 20110101
A template-dependent dislocation mechanism potentiates K65R reverse transcriptase mutation development in subtype C variants of HIV-1. PloS one 20110101
Oxidative DNA damage in lung tissue from patients with COPD is clustered in functionally significant sequences. International journal of chronic obstructive pulmonary disease 20110101
A large scale comparative genomic analysis reveals insertion sites for newly acquired genomic islands in bacterial genomes. BMC microbiology 20110101
Therapeutic potential of cladribine in combination with STAT3 inhibitor against multiple myeloma. BMC cancer 20110101
Comparative analysis of macrophage associated vectors for use in genetic vaccine. Genetic vaccines and therapy 20110101
Development and validation of a novel molecular biomarker diagnostic test for the early detection of sepsis. Critical care (London, England) 20110101
Dissimilar roles of the four conserved acidic residues in the thermal stability of poly(A)-specific ribonuclease. International journal of molecular sciences 20110101
Therapeutic effects of hydrogen in animal models of Parkinson's disease. Parkinson's disease 20110101
Two-stage flux balance analysis of metabolic networks for drug target identification. BMC systems biology 20110101
Genome-wide analysis of the transcription factor binding preference of human bi-directional promoters and functional annotation of related gene pairs. BMC systems biology 20110101
Evolutionary history of Otophysi (Teleostei), a major clade of the modern freshwater fishes: Pangaean origin and Mesozoic radiation. BMC evolutionary biology 20110101
Diploid-specific [corrected] genome stability genes of S. cerevisiae: genomic screen reveals haploidization as an escape from persisting DNA rearrangement stress. PloS one 20110101
Bendamustine: safety and efficacy in the management of indolent non-hodgkins lymphoma. Clinical Medicine Insights. Oncology 20110101
Iwr1 protein is important for preinitiation complex formation by all three nuclear RNA polymerases in Saccharomyces cerevisiae. PloS one 20110101
Extracellular purine and pyrimidine catabolism in cell culture. Biotechnology progress 20110101
Review and application of group theory to molecular systems biology. Theoretical biology & medical modelling 20110101
Proteomic patterns of cervical cancer cell lines, a network perspective. BMC systems biology 20110101
The evolution of enzyme specificity in the metabolic replicator model of prebiotic evolution. PloS one 20110101
Collective dynamics of gene expression in cell populations. PloS one 20110101
Global transcriptome response in Lactobacillus sakei during growth on ribose. BMC microbiology 20110101
Comparative expression profiling of E. coli and S. aureus inoculated primary mammary gland cells sampled from cows with different genetic predispositions for somatic cell score. Genetics, selection, evolution : GSE 20110101
In vivo versus in vitro protein abundance analysis of Shigella dysenteriae type 1 reveals changes in the expression of proteins involved in virulence, stress and energy metabolism. BMC microbiology 20110101
Exploring internal features of 16S rRNA gene for identification of clinically relevant species of the genus Streptococcus. Annals of clinical microbiology and antimicrobials 20110101
Zinc finger protein ZBTB20 expression is increased in hepatocellular carcinoma and associated with poor prognosis. BMC cancer 20110101
Regulation of gene expression in ovarian cancer cells by luteinizing hormone receptor expression and activation. BMC cancer 20110101
Carbon composite micro- and nano-tubes-based electrodes for detection of nucleic acids. Nanoscale research letters 20110101
Epidemiology of therapy-related myeloid neoplasms after treatment for pediatric acute lymphoblastic leukemia in the nordic countries. Mediterranean journal of hematology and infectious diseases 20110101
Energetics and genetics across the prokaryote-eukaryote divide. Biology direct 20110101
The effects of oral Ginkgo biloba supplementation on radiation-induced oxidative injury in the lens of rat. Pharmacognosy magazine 20110101
Use of specific chemical reagents for detection of modified nucleotides in RNA. Journal of nucleic acids 20110101
P2Y receptors as regulators of lung endothelial barrier integrity. Journal of cardiovascular disease research 20110101
Genome-wide expression quantitative trait loci (eQTL) analysis in maize. BMC genomics 20110101
Metabolic myopathy presenting with polyarteritis nodosa: a case report. Journal of medical case reports 20110101
[Efficacy and safety of combination therapy with mizoribine and methotrexate for rheumatoid arthritis resistant with methotrexate]. Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20110101
Alanine racemase mutants of Burkholderia pseudomallei and Burkholderia mallei and use of alanine racemase as a non-antibiotic-based selectable marker. PloS one 20110101
An efficient approach to finding Siraitia grosvenorii triterpene biosynthetic genes by RNA-seq and digital gene expression analysis. BMC genomics 20110101
Simultaneous clinical resolution of focal segmental glomerulosclerosis associated with chronic lymphocytic leukaemia treated with fludarabine, cyclophosphamide and rituximab. BMC nephrology 20110101
Potential activity of the purine compounds caffeine and aminophylline on bacteria. Journal of global infectious diseases 20110101
Individual variations in inorganic arsenic metabolism associated with AS3MT genetic polymorphisms. International journal of molecular sciences 20110101
The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner. PloS one 20110101
4D Flexible Atom-Pairs: An efficient probabilistic conformational space comparison for ligand-based virtual screening. Journal of cheminformatics 20110101
GABA(A) Receptors: Post-Synaptic Co-Localization and Cross-Talk with Other Receptors. Frontiers in cellular neuroscience 20110101
B vitamins, methionine and alcohol intake and risk of colon cancer in relation to BRAF mutation and CpG island methylator phenotype (CIMP). PloS one 20110101
Comparative genomics and transcriptomics of Propionibacterium acnes. PloS one 20110101
Crystal structures of histone and p53 methyltransferase SmyD2 reveal a conformational flexibility of the autoinhibitory C-terminal domain. PloS one 20110101
Enzymes are enriched in bacterial essential genes. PloS one 20110101
Molecular characterization of the uncultivatable hemotropic bacterium Mycoplasma haemofelis. Veterinary research 20110101
The role of the C8 proton of ATP in the regulation of phosphoryl transfer within kinases and synthetases. BMC biochemistry 20110101
Genome-wide mutagenesis of Xanthomonas axonopodis pv. citri reveals novel genetic determinants and regulation mechanisms of biofilm formation. PloS one 20110101
Molecular and cellular pathways associated with chromosome 1p deletions during colon carcinogenesis. Clinical and experimental gastroenterology 20110101
E. coli histidine triad nucleotide binding protein 1 (ecHinT) is a catalytic regulator of D-alanine dehydrogenase (DadA) activity in vivo. PloS one 20110101
Inorganic phosphate as an important regulator of phosphatases. Enzyme research 20110101
Molecular Cloning and Characterization of P4 Nuclease from Leishmania infantum. Enzyme research 20110101
Transplantable subcutaneous hepatoma 22a affects functional activity of resident tissue macrophages in periphery. International journal of cell biology 20110101
Should metabolic diseases be systematically screened in nonsyndromic autism spectrum disorders? PloS one 20110101
Comparative Proteomic Analysis of saccharopolyspora spinosa SP06081 and PR2 strains reveals the differentially expressed proteins correlated with the increase of spinosad yield. Proteome science 20110101
Investigation of the Staphylococcus aureus GraSR regulon reveals novel links to virulence, stress response and cell wall signal transduction pathways. PloS one 20110101
Sirtuins, bioageing, and cancer. Journal of aging research 20110101
Absolute quantification of microbial proteomes at different states by directed mass spectrometry. Molecular systems biology 20110101
Conformational-dependent and independent RNA binding to the fragile x mental retardation protein. Journal of nucleic acids 20110101
Identification of the DNA-Binding Domains of Human Replication Protein A That Recognize G-Quadruplex DNA. Journal of nucleic acids 20110101
Advances in fine needle aspiration cytology for the diagnosis of pulmonary carcinoma. Pathology research international 20110101
Metabolomics in early Alzheimer's disease: identification of altered plasma sphingolipidome using shotgun lipidomics. PloS one 20110101
Generation, analysis and functional annotation of expressed sequence tags from the ectoparasitic mite Psoroptes ovis. Parasites & vectors 20110101
8-Aminoadenosine enhances radiation-induced cell death in human lung carcinoma A549 cells. Journal of radiation research 20110101
Acupuncture May Stimulate Anticancer Immunity via Activation of Natural Killer Cells. Evidence-based complementary and alternative medicine : eCAM 20110101
Acid phosphatases of budding yeast as a model of choice for transcription regulation research. Enzyme research 20110101
A high protein diet during pregnancy affects hepatic gene expression of energy sensing pathways along ontogenesis in a porcine model. PloS one 20110101
Energy metabolism in H460 lung cancer cells: effects of histone deacetylase inhibitors. PloS one 20110101
An integrated bioinformatics approach identifies elevated cyclin E2 expression and E2F activity as distinct features of tamoxifen resistant breast tumors. PloS one 20110101
Clinical relevance and treatment of nonautoimmune anemia in chronic lymphocytic leukemia. Cancer management and research 20110101
The impact of fructose on renal function and blood pressure. International journal of nephrology 20110101
New insights in the removal of the hydantoins, oxidation product of pyrimidines, via the base excision and nucleotide incision repair pathways. PloS one 20110101
Sequence-dependent fluorescence of cyanine dyes on microarrays. PloS one 20110101
Exploiting publicly available biological and biochemical information for the discovery of novel short linear motifs. PloS one 20110101
Zinc-regulated DNA binding of the yeast Zap1 zinc-responsive activator. PloS one 20110101
SEAS: a system for SEED-based pathway enrichment analysis. PloS one 20110101
A cell-based assay for RNA synthesis by the HCV polymerase reveals new insights on mechanism of polymerase inhibitors and modulation by NS5A. PloS one 20110101
Systems biology of bacterial nitrogen fixation: high-throughput technology and its integrative description with constraint-based modeling. BMC systems biology 20110101
Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats. Nutrition & metabolism 20110101
Large-scale RNAi screen of G protein-coupled receptors involved in larval growth, molting and metamorphosis in the red flour beetle. BMC genomics 20110101
Comparative genomic reconstruction of transcriptional networks controlling central metabolism in the Shewanella genus. BMC genomics 20110101
Metabolic network reconstruction of Chlamydomonas offers insight into light-driven algal metabolism. Molecular systems biology 20110101
Identification of new IS711 insertion sites in Brucella abortus field isolates. BMC microbiology 20110101
Serum uric acid level and its association with metabolic syndrome and carotid atherosclerosis in patients with type 2 diabetes. Cardiovascular diabetology 20110101
Polyphosphate--an ancient energy source and active metabolic regulator. Microbial cell factories 20110101
Efficient overproduction of membrane proteins in Lactococcus lactis requires the cell envelope stress sensor/regulator couple CesSR. PloS one 20110101
PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse. PloS one 20110101
Synergistic interactions between HDAC and sirtuin inhibitors in human leukemia cells. PloS one 20110101
Proteomic analysis of anti-tumor effects of 11-dehydrosinulariolide on CAL-27 cells. Marine drugs 20110101
Use of nucleic Acid analogs for the study of nucleic Acid interactions. Journal of nucleic acids 20110101
Structural diversity of biologically interesting datasets: a scaffold analysis approach. Journal of cheminformatics 20110101
Nicotinamide phosphoribosyltransferase/visfatin does not catalyze nicotinamide mononucleotide formation in blood plasma. PloS one 20110101
Pancreatic β-cell death in response to pro-inflammatory cytokines is distinct from genuine apoptosis. PloS one 20110101
Culture enriched molecular profiling of the cystic fibrosis airway microbiome. PloS one 20110101
Proteomic analysis reveals that iron availability alters the metabolic status of the pathogenic fungus Paracoccidioides brasiliensis. PloS one 20110101
Structural basis for sequence specific DNA binding and protein dimerization of HOXA13. PloS one 20110101
Differential inhibitor sensitivity between human kinases VRK1 and VRK2. PloS one 20110101
Lipopolysaccharide-Deficient Brucella Variants Arise Spontaneously during Infection. Frontiers in microbiology 20110101
Integrating systems biology models and biomedical ontologies. BMC systems biology 20110101
Attenuation of virulence in an apicomplexan hemoparasite results in reduced genome diversity at the population level. BMC genomics 20110101
[The activity of antioxidant enzymes of erythrocytes under intensive physical activity on the background of D-ribose use]. Voprosy pitaniia 20110101
Selection of hepatitis C virus resistant to ribavirin. Virology journal 20110101
Current and emerging treatments for the management of myasthenia gravis. Therapeutics and clinical risk management 20110101
Variations of antioxidant properties and NO scavenging abilities during fermentation of tea. International journal of molecular sciences 20110101
Clinical pharmacology of chemotherapy agents in older people with cancer. Current gerontology and geriatrics research 20110101
Oncogenic K-Ras decouples glucose and glutamine metabolism to support cancer cell growth. Molecular systems biology 20110101
The relationship between serum uric acid and spirometric values in participants in a health check: the Takahata study. International journal of medical sciences 20110101
Gas6 downregulation impaired cytoplasmic maturation and pronuclear formation independent to the MPF activity. PloS one 20110101
DARS-RNP and QUASI-RNP: new statistical potentials for protein-RNA docking. BMC bioinformatics 20110101
The nucleotide exchange factor Ric-8A is a chaperone for the conformationally dynamic nucleotide-free state of Gαi1. PloS one 20110101
Involvement of cytokines in slow wave sleep. Progress in brain research 20110101
A crystal structure of the catalytic core domain of an avian sarcoma and leukemia virus integrase suggests an alternate dimeric assembly. PloS one 20110101
Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8. PloS one 20110101
Importance of suitable reference gene selection for quantitative real-time PCR: special reference to mouse myocardial infarction studies. PloS one 20110101
Genome sequencing reveals diversification of virulence factor content and possible host adaptation in distinct subpopulations of Salmonella enterica. BMC genomics 20110101
Distinct configurations of protein complexes and biochemical pathways revealed by epistatic interaction network motifs. BMC systems biology 20110101
Cross-Genome Comparisons of Newly Identified Domains in Mycoplasma gallisepticum and Domain Architectures with Other Mycoplasma species. Comparative and functional genomics 20110101
Purification and characterization of cytoplasmic NADP+-isocitrate dehydrogenase, and amplification of the NADP+-IDH gene from the wing-dimorphic sand field cricket, Gryllus firmus. Journal of insect science (Online) 20110101
Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancer. BMC cancer 20110101
P53 suppresses expression of the 14-3-3 gamma oncogene. BMC cancer 20110101
Therapy-Related Myeloid Neoplasms in Chronic Lymphocytic Leukemia and Waldenstrom's Macroglobulinemia. Mediterranean journal of hematology and infectious diseases 20110101
Comparison of the 'Ca. Liberibacter asiaticus' genome adapted for an intracellular lifestyle with other members of the Rhizobiales. PloS one 20110101
Integrating transcriptomics and metabonomics to unravel modes-of-action of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in HepG2 cells. BMC systems biology 20110101
Bacterial Catabolism of Dimethylsulfoniopropionate (DMSP). Frontiers in microbiology 20110101
Characterisation of genome-wide association epistasis signals for serum uric acid in human population isolates. PloS one 20110101
Design, Synthesis and Biological Evaluation of Novel Pyrimido[4,5-d]pyrimidine CDK2 Inhibitors as Anti-Tumor Agents. Scientia pharmaceutica 20110101
Tissue-specific Salmonella Typhimurium gene expression during persistence in pigs. PloS one 20110101
Cellular kinases incorporated into HIV-1 particles: passive or active passengers? Retrovirology 20110101
Biochemical measurement of neonatal hypoxia. Journal of visualized experiments : JoVE 20110101
Identification of ionotrophic purinergic receptors in Huh-7 cells and their response towards structural proteins of HCV genotype 3a. Virology journal 20110101
Promising pharmacological, molecular and cellular treatments of autoimmune hepatitis. Current pharmaceutical design 20110101
Fragmentation of contaminant and endogenous DNA in ancient samples determined by shotgun sequencing; prospects for human palaeogenomics. PloS one 20110101
Structural mechanism of S-adenosyl methionine binding to catechol O-methyltransferase. PloS one 20110101
Cell-specific aptamers as emerging therapeutics. Journal of nucleic acids 20110101
Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia. Clinical proteomics 20110101
Phospholipase C isozymes are deregulated in colorectal cancer--insights gained from gene set enrichment analysis of the transcriptome. PloS one 20110101
Oxidative DNA Damage in Blood of CVD Patients Taking Detralex. The open cardiovascular medicine journal 20110101
[Inborn errors of purine and pyrimidyne metabolism]. Postepy biochemii 20110101
Clostridium difficile Infection and Inflammatory Bowel Disease: A Review. Gastroenterology research and practice 20110101
Macrophage replication screen identifies a novel Francisella hydroperoxide resistance protein involved in virulence. PloS one 20110101
Ex vivo expansion of human hematopoietic stem cells by garcinol, a potent inhibitor of histone acetyltransferase. PloS one 20110101
Phosphorylation provides a negative mode of regulation for the yeast Rab GTPase Sec4p. PloS one 20110101
Determinants, discriminants, conserved residues--a heuristic approach to detection of functional divergence in protein families. PloS one 20110101
Metagenome plasticity of the bovine abomasal microbiota in immune animals in response to Ostertagia ostertagi infection. PloS one 20110101
Differential proteome analysis of human embryonic kidney cell line (HEK-293) following mycophenolic acid treatment. Proteome science 20110101
Protection from experimental cerebral malaria with a single dose of radiation-attenuated, blood-stage Plasmodium berghei parasites. PloS one 20110101
Gene expression changes in phosphorus deficient potato (Solanum tuberosum L.) leaves and the potential for diagnostic gene expression markers. PloS one 20110101
Functional characterization of the dendritically localized mRNA neuronatin in hippocampal neurons. PloS one 20110101
The genetic basis of salinity tolerance traits in Arctic charr (Salvelinus alpinus). BMC genetics 20110101
Genome of Mycoplasma haemofelis, unraveling its strategies for survival and persistence. Veterinary research 20110101
Lipopolysaccharide inhibits the channel activity of the P2X7 receptor. Mediators of inflammation 20110101
Establishing a markerless genetic exchange system for Methanosarcina mazei strain Gö1 for constructing chromosomal mutants of small RNA genes. Archaea (Vancouver, B.C.) 20110101
Synthetic RNA silencing in bacteria - antimicrobial discovery and resistance breaking. Frontiers in microbiology 20110101
Yeast processing bodies and stress granules: self-assembly ribonucleoprotein particles. Microbial cell factories 20110101
Serum uri acid: neuroprotection in thrombolysis. The Bergen NORSTROKE study. BMC neurology 20110101
A comparative study on gene-set analysis methods for assessing differential expression associated with the survival phenotype. BMC bioinformatics 20110101
How yeast re-programmes its transcriptional profile in response to different nutrient impulses. BMC systems biology 20110101
Ceruloplasmin deficiency reduces levels of iron and BDNF in the cortex and striatum of young mice and increases their vulnerability to stroke. PloS one 20110101
Targeting pannexin1 improves seizure outcome. PloS one 20110101
Characterization of the biosynthesis, processing and kinetic mechanism of action of the enzyme deficient in mucopolysaccharidosis IIIC. PloS one 20110101
Mizoribine provides effective treatment of sequential histological change of arteritis and reduction of inflammatory cytokines and chemokines in an animal model of Kawasaki disease. Pediatric rheumatology online journal 20110101
Complexity of bidirectional transcription and alternative splicing at human RCAN3 locus. PloS one 20110101
Oral voclosporin: novel calcineurin inhibitor for treatment of noninfectious uveitis. Clinical ophthalmology (Auckland, N.Z.) 20110101
D-ribose induces cellular protein glycation and impairs mouse spatial cognition. PloS one 20110101
Exploring DNA topoisomerase I ligand space in search of novel anticancer agents. PloS one 20110101
The eukaryotic-type serine/threonine protein kinase Stk is required for biofilm formation and virulence in Staphylococcus epidermidis. PloS one 20110101
Clinical and genetic analyses of three Korean families with hereditary hemorrhagic telangiectasia. BMC medical genetics 20110101
Differential chromatin proteomics of the MMS-induced DNA damage response in yeast. Proteome science 20110101
Enrollment characteristics and risk behaviors of injection drug users participating in the Bangkok Tenofovir Study, Thailand. PloS one 20110101
Deoxyribozymes: new therapeutics to treat central nervous system disorders. Frontiers in molecular neuroscience 20110101
Non-B DNA Secondary Structures and Their Resolution by RecQ Helicases. Journal of nucleic acids 20110101
Adaptation of organisms by resonance of RNA transcription with the cellular redox cycle. PloS one 20110101
Development of vaccines against burkholderia pseudomallei. Frontiers in microbiology 20110101
Immunomodulators and immunosuppressants for Japanese patients with ulcerative colitis. ISRN gastroenterology 20110101
Role of mucosal inflammation in eosinophilic esophagitis: review of the literature. ISRN gastroenterology 20110101
Regulation of the yeast metabolic cycle by transcription factors with periodic activities. BMC systems biology 20110101
The Antifungal Plant Defensin HsAFP1 from Heuchera sanguinea Induces Apoptosis in Candida albicans. Frontiers in microbiology 20110101
Specialized adaptation of a lactic acid bacterium to the milk environment: the comparative genomics of Streptococcus thermophilus LMD-9. Microbial cell factories 20110101
Genome sequences and comparative genomics of two Lactobacillus ruminis strains from the bovine and human intestinal tracts. Microbial cell factories 20110101
Some aspects of purinergic signaling in the ventricular system of porcine brain. Acta veterinaria Scandinavica 20110101
Internal control genes for quantitative RT-PCR expression analysis in mouse osteoblasts, osteoclasts and macrophages. BMC research notes 20110101
Dithizone staining of intracellular zinc: an unexpected and versatile counterscreen for auxotrophic marker genes in Saccharomyces cerevisiae. PloS one 20110101
A system for performing high throughput assays of synaptic function. PloS one 20110101
Perfluoroalkyl chemicals and elevated serum uric acid in US adults. Clinical epidemiology 20110101
Adenosine receptors and fibrosis: a translational review. F1000 biology reports 20110101
Antivirals reduce the formation of key Alzheimer's disease molecules in cell cultures acutely infected with herpes simplex virus type 1. PloS one 20110101
Molecular organization and phylogenetic analysis of 5S rDNA in crustaceans of the genus Pollicipes reveal birth-and-death evolution and strong purifying selection. BMC evolutionary biology 20110101
Comparative genomics of the pathogenic ciliate Ichthyophthirius multifiliis, its free-living relatives and a host species provide insights into adoption of a parasitic lifestyle and prospects for disease control. Genome biology 20110101
Strategies for Intracellular Survival of Burkholderia pseudomallei. Frontiers in microbiology 20110101
tRNA Modification and Genetic Code Variations in Animal Mitochondria. Journal of nucleic acids 20110101
Transcriptome analysis of Aspergillus niger grown on sugarcane bagasse. Biotechnology for biofuels 20110101
Comparative shotgun proteomic analysis of Clostridium acetobutylicum from butanol fermentation using glucose and xylose. Proteome science 20110101
Hydration sites of unpaired RNA bases: a statistical analysis of the PDB structures. BMC structural biology 20110101
Synthesis of specifically modified oligonucleotides for application in structural and functional analysis of RNA. Journal of nucleic acids 20110101
The transcriptome of the novel dinoflagellate Oxyrrhis marina (Alveolata: Dinophyceae): response to salinity examined by 454 sequencing. BMC genomics 20110101
pcrEfficiency: a Web tool for PCR amplification efficiency prediction. BMC bioinformatics 20110101
Academic aspects of lunar water resources and their relevance to lunar protolife. International journal of molecular sciences 20110101
Association of reactive oxygen species-mediated signal transduction with in vitro apoptosis sensitivity in chronic lymphocytic leukemia B cells. PloS one 20110101
Integrated proteomic and metabolomic analysis of an artificial microbial community for two-step production of vitamin C. PloS one 20110101
The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets. BMC microbiology 20110101
Evaluation of the concomitant use of methotrexate and curcumin on Freund's complete adjuvant-induced arthritis and hematological indices in rats. Indian journal of pharmacology 20110101
Preventive fluid and dietary therapy for urolithiasis: An appraisal of strength, controversies and lacunae of current literature. Indian journal of urology : IJU : journal of the Urological Society of India 20110101
Comparison of azathioprine with mycophenolate mofetil in a living donor kidney transplant programme. Indian journal of nephrology 20110101
Transcriptome analysis of adaptive heat shock response of Streptococcus thermophilus. PloS one 20110101
Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme. PloS one 20110101
Purinergic signaling induces cyclooxygenase-1-dependent prostanoid synthesis in microglia: roles in the outcome of excitotoxic brain injury. PloS one 20110101
Folate metabolic pathways in Leishmania. Essays in biochemistry 20110101
Genome-wide assessment of the carriers involved in the cellular uptake of drugs: a model system in yeast. BMC biology 20110101
PMS5: an efficient exact algorithm for the (ℓ, d)-motif finding problem. BMC bioinformatics 20110101
Energy drinks and the neurophysiological impact of caffeine. Frontiers in neuroscience 20110101
Cyclin-Dependent Kinase 5/p35/p39: A Novel and Imminent Therapeutic Target for Diabetes Mellitus. International journal of endocrinology 20110101
Identification of gene expression signature modulated by nicotinamide in a mouse bladder cancer model. PloS one 20110101
Oncolytic adenoviruses armed with thymidine kinase can be traced by PET imaging and show potent antitumoural effects by ganciclovir dosing. PloS one 20110101
In vivo rescue of alveolar macrophages from SP-A knockout mice with exogenous SP-A nearly restores a wild type intracellular proteome; actin involvement. Proteome science 20110101
Recent progress in the study of brown adipose tissue. Cell & bioscience 20110101
A thiopurine drug inhibits West Nile virus production in cell culture, but not in mice. PloS one 20110101
Polyamidoamine (PAMAM) dendrimer conjugate specifically activates the A3 adenosine receptor to improve post-ischemic/reperfusion function in isolated mouse hearts. BMC pharmacology 20110101
The evolution of metabolic networks of E. coli. BMC systems biology 20110101
In vivo and in silico determination of essential genes of Campylobacter jejuni. BMC genomics 20110101
Hepatitis B virus impairs TLR9 expression and function in plasmacytoid dendritic cells. PloS one 20110101
An alignment-free approach for eukaryotic ITS2 annotation and phylogenetic inference. PloS one 20110101
Transcriptional and functional analysis of the effects of magnolol: inhibition of autolysis and biofilms in Staphylococcus aureus. PloS one 20110101
Composite effects of gene determinants on the translation speed and density of ribosomes. Genome biology 20110101
Reversine increases multipotent human mesenchymal cells differentiation potential. Journal of biological regulators and homeostatic agents 20110101
Impact of manganese, copper and zinc ions on the transcriptome of the nosocomial pathogen Enterococcus faecalis V583. PloS one 20110101
Complete genome sequence of Corynebacterium variabile DSM 44702 isolated from the surface of smear-ripened cheeses and insights into cheese ripening and flavor generation. BMC genomics 20110101
GSK-3 Inhibitors: Preclinical and Clinical Focus on CNS. Frontiers in molecular neuroscience 20110101
Gout, genetics and ABC transporters. F1000 biology reports 20110101
Metabolomics of oxidative stress in recent studies of endogenous and exogenously administered intermediate metabolites. International journal of molecular sciences 20110101
Kinase inhibitors from marine sponges. Marine drugs 20110101
The role of muscarinic receptors in the beneficial effects of adenosine against myocardial reperfusion injury in rats. PloS one 20110101
Phylogenetic diversity, host-specificity and community profiling of sponge-associated bacteria in the northern Gulf of Mexico. PloS one 20110101
Redox-based inactivation of cysteine cathepsins by compounds containing the 4-aminophenol moiety. PloS one 20110101
Proteome analysis of bronchoalveolar lavage in pulmonary langerhans cell histiocytosis. Journal of clinical bioinformatics 20110101
The synthesis of C8-aryl purines, nucleosides and phosphoramidites. Critical reviews in eukaryotic gene expression 20110101
Mechanisms of B cell autoimmunity in SLE. Arthritis research & therapy 20110101
A Systematic Review and Meta-Analysis of Front-line Anthracycline-Based Chemotherapy Regimens for Peripheral T-Cell Lymphoma. ISRN hematology 20110101
Time-resolved transcriptomics and bioinformatic analyses reveal intrinsic stress responses during batch culture of Bacillus subtilis. PloS one 20110101
Gene expression-based chemical genomics identifies potential therapeutic drugs in hepatocellular carcinoma. PloS one 20110101
A plant virus movement protein regulates the Gcn2p kinase in budding yeast. PloS one 20110101
8-Modified-2'-deoxyadenosine analogues induce delayed polymerization arrest during HIV-1 reverse transcription. PloS one 20110101
The role of purinergic signaling on deformation induced injury and repair responses of alveolar epithelial cells. PloS one 20110101
Experimental Chemotherapy for Chagas Disease: A Morphological, Biochemical, and Proteomic Overview of Potential Trypanosoma cruzi Targets of Amidines Derivatives and Naphthoquinones. Molecular biology international 20110101
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Prediction of dinucleotide-specific RNA-binding sites in proteins. BMC bioinformatics 20110101
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Defining the plant peroxisomal proteome: from Arabidopsis to rice. Frontiers in plant science 20110101
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Exploring new inhibitors of Plasmodium falciparum purine nucleoside phosphorylase. European journal of medicinal chemistry 20101101
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The spermine-bisaryl conjugate as a potent inducer of B- to Z-DNA transition. Chemistry (Weinheim an der Bergstrasse, Germany) 20101018
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Electrochemical determination of guanine and adenine by CdS microspheres modified electrode and evaluation of damage to DNA purine bases by UV radiation. Biosensors & bioelectronics 20101015
A class of novel conjugates of substituted purine and Gly-AA-OBzl: synthesis and evaluation of orally analgesic activity. Bioorganic & medicinal chemistry letters 20101015
Synthesis of non-purine analogs of 6-aryl-9-benzylpurines, and their antimycobacterial activities. Compounds modified in the imidazole ring. Bioorganic & medicinal chemistry 20101015
One-pot etherification of purine nucleosides and pyrimidines. Organic letters 20101015
In vitro and in vivo trypanocidal evaluation of nickel complexes with an azapurine derivative against Trypanosoma cruzi. Journal of medicinal chemistry 20101014
Analysis of the HPRT1 gene in 35 Italian Lesch-Nyhan families: 45 patients and 77 potential female carriers. Mutation research 20101013
A pharmacy practice laboratory exercise to apply biochemistry concepts. American journal of pharmaceutical education 20101011
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Purine metabolite levels in preovulatory human follicles may hold the key to ovarian hyperstimulation syndrome. Metabolism: clinical and experimental 20101001
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Metabolomic profiling reveals biochemical pathways and biomarkers associated with pathogenesis in cystic fibrosis cells. The Journal of biological chemistry 20101001
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Enzyme catalysis from improved packing in their transition-state structures. Current opinion in chemical biology 20101001
Investigation of riboflavin sensitized degradation of purine and pyrimidine derivatives of DNA and RNA under UVA and UVB. Biochemical and biophysical research communications 20101001
Modelling the effects of inhibitors of guanine nucleotide synthesis: implications for studies of cellular differentiation pathways. Biochemical Society transactions 20101001
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Testing the theory of immune selection in cancers that break the rules of transplantation. Cancer immunology, immunotherapy : CII 20100501
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Metabolomic study of myocardial ischemia and intervention effects of Compound Danshen Tablets in rats using ultra-performance liquid chromatography/quadrupole time-of-flight mass spectrometry. Journal of pharmaceutical and biomedical analysis 20100501
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1H and 13C resonance assignments of a guanine sensing riboswitch's terminator hairpin. Biomolecular NMR assignments 20100401
Purine derivatives as potent gamma-secretase modulators. Bioorganic & medicinal chemistry letters 20100401
Human polymerase alpha inhibitors for skin tumors. Part 2. Modeling, synthesis and influence on normal and transformed keratinocytes of new thymidine and purine derivatives. Journal of enzyme inhibition and medicinal chemistry 20100401
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Clinical trials for human T-cell lymphotropic virus type I-associated peripheral T-cell lymphoma in Japan. Seminars in hematology 20100401
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A microarray-based genetic screen for yeast chronological aging factors. PLoS genetics 20100401
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Intramolecular cation-pi interactions as the driving force to restrict the conformation of certain nucleosides. The Journal of organic chemistry 20100319
Accurate guanine:cytosine discrimination in T4 DNA ligase-based single nucleotide polymorphism analysis using an oxanine-containing ligation fragment. Analytical biochemistry 20100315
Detoxication of sulfur half-mustards by nucleophilic scavengers: robust activity of thiopurines. Chemical research in toxicology 20100315
Structural-based design and synthesis of novel 9-deazaguanine derivatives having a phosphate mimic as multi-substrate analogue inhibitors for mammalian PNPs. Bioorganic & medicinal chemistry 20100315
Structure of the RNA 3'-phosphate cyclase-adenylate intermediate illuminates nucleotide specificity and covalent nucleotidyl transfer. Structure (London, England : 1993) 20100314
Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels. The Journal of biological chemistry 20100312
The crystal structure and activity of a putative trypanosomal nucleoside phosphorylase reveal it to be a homodimeric uridine phosphorylase. Journal of molecular biology 20100312
Discovery of 4-amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamides as selective, orally active inhibitors of protein kinase B (Akt). Journal of medicinal chemistry 20100311
Electronic signatures of all four DNA nucleosides in a tunneling gap. Nano letters 20100310
Conformational states of human purine nucleoside phosphorylase at rest, at work, and with transition state analogues. Biochemistry 20100309
Preparation of the 2'-deoxynucleosides of 2,6-diaminopurine and isoguanine by direct glycosylation. The Journal of organic chemistry 20100305
Multivector fluorescence analysis of the xpt guanine riboswitch aptamer domain and the conformational role of guanine. Biochemistry 20100302
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Covalent hydration energies for purine analogs by quantum chemical methods. Journal of computational chemistry 20100301
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Molecular dynamics studies of a hexameric purine nucleoside phosphorylase. Journal of molecular modeling 20100301
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Genotoxic effects of neutrophils and hypochlorous acid. Mutagenesis 20100301
Crystal structure and molecular dynamics studies of human purine nucleoside phosphorylase complexed with 7-deazaguanine. Journal of structural biology 20100301
High-throughput binding analysis determines the binding specificity of ASF/SF2 on alternatively spliced human pre-mRNAs. Combinatorial chemistry & high throughput screening 20100301
1st UK Purine Symposium: 19th November 2009. Purinergic signalling 20100301
The missing link in plant histidine biosynthesis: Arabidopsis myoinositol monophosphatase-like2 encodes a functional histidinol-phosphate phosphatase. Plant physiology 20100301
Defective repair of 5-hydroxy-2'-deoxycytidine in Cockayne syndrome cells and its complementation by Escherichia coli formamidopyrimidine DNA glycosylase and endonuclease III. Free radical biology & medicine 20100301
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Equilibrative nucleoside transporter 1 plays an essential role in cardioprotection. American journal of physiology. Heart and circulatory physiology 20100301
The A2aR adenosine receptor controls cytokine production in iNKT cells. European journal of immunology 20100301
The role of oxidative DNA damage, DNA repair, GSTM1, SOD2 and OGG1 polymorphisms in individual susceptibility to Barrett's esophagus. Toxicology and industrial health 20100301
Cloning, purification and characterisation of a recombinant purine nucleoside phosphorylase from Bacillus halodurans Alk36. Extremophiles : life under extreme conditions 20100301
Functional characterization and virulence study of ADE8 and GUA1 genes involved in the de novo purine biosynthesis in Candida albicans. FEMS yeast research 20100301
Reconstruction of metabolic pathways, protein expression, and homeostasis machineries across maize bundle sheath and mesophyll chloroplasts: large-scale quantitative proteomics using the first maize genome assembly. Plant physiology 20100301
Bioactivity and molecular targets of novel substituted quinolines in murine and human tumor cell lines in vitro. International journal of oncology 20100301
Mechanisms involved in the antinociception induced by systemic administration of guanosine in mice. British journal of pharmacology 20100301
Molecular genetics of attention-deficit/hyperactivity disorder: an overview. European child & adolescent psychiatry 20100301
Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder. European child & adolescent psychiatry 20100301
Attenuated variants of Lesch-Nyhan disease. Brain : a journal of neurology 20100301
Multiple receptor tyrosine kinases are expressed in adult rat retinal ganglion cells as revealed by single-cell degenerate primer polymerase chain reaction. Upsala journal of medical sciences 20100301
Synthesis and properties of diazirinyl organo-platinum compounds for manipulations of photoaffinity labeled components. Chemical & pharmaceutical bulletin 20100301
Potential role of uric Acid as a risk factor for cardiovascular disease. The Korean journal of internal medicine 20100301
Computational methods for de novo protein design and its applications to the human immunodeficiency virus 1, purine nucleoside phosphorylase, ubiquitin specific protease 7, and histone demethylases. Current drug targets 20100301
MolDock applied to structure-based virtual screening. Current drug targets 20100301
Separation of purine and pyrimidine bases and nucleosides by hydrophilic interaction chromatography. Journal of separation science 20100301
Xanthine urolithiasis. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100301
Effects of 5'-adenosine triphosphate on intestinal ischemia-reperfusion in rabbits. Transplantation proceedings 20100301
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Evidence for the hypothesis that 10-formyldihydrofolate is the in vivo substrate for aminoimidazolecarboxamide ribotide transformylase. Experimental biology and medicine (Maywood, N.J.) 20100301
Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage. Nucleosides, nucleotides & nucleic acids 20100301
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Complete genomic sequence of bacteriophage felix o1. Viruses 20100301
Mini-exon genotyping of leishmania species in khuzestan province, southwest iran. Iranian journal of parasitology 20100301
Increase in backbone mobility of the VTS1p-SAM domain on binding to SRE-RNA. Journal of molecular biology 20100226
Role of transmembrane domain 4 in ligand permeation by Crithidia fasciculata equilibrative nucleoside transporter 2 (CfNT2). The Journal of biological chemistry 20100226
Study on intestinal absorption sites of mizoribine and ribavirin, substrates for concentrative nucleoside transporter(s), in rats. European journal of pharmacology 20100225
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Chemical basis of nitrogen recovery through the ureide pathway: formation and hydrolysis of S-ureidoglycine in plants and bacteria. ACS chemical biology 20100219
Enzymatic processing of platinated RNAs. Journal of the American Chemical Society 20100217
Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies. Bioorganic & medicinal chemistry 20100215
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Synthesis and antitumor activity of a novel series of 6-substituted pyrrolo[2,3-d]pyrimidine thienoyl antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors and the proton-coupled folate transporter over the reduced folate carrier for cellular entry. Journal of medicinal chemistry 20100211
Chlorophenols, chlorocatechols and chloroguaiacols induce DNA base oxidation in human lymphocytes (in vitro). Toxicology 20100209
One-electron oxidation of individual DNA bases and DNA base stacks. The journal of physical chemistry. A 20100204
13C chemical shift tensors in hypoxanthine and 6-mercaptopurine: effects of substitution, tautomerism, and intermolecular interactions. The journal of physical chemistry. A 20100204
Mechanisms by which human DNA primase chooses to polymerize a nucleoside triphosphate. Biochemistry 20100202
Structural and functional studies of Aspergillus clavatus N(5)-carboxyaminoimidazole ribonucleotide synthetase . Biochemistry 20100202
The role of folate receptor alpha (FRalpha) in the response of malignant pleural mesothelioma to pemetrexed-containing chemotherapy. British journal of cancer 20100202
Association of serum uric acid levels with emotional and affective temperaments. Journal of affective disorders 20100201
Guanosine prevents thermal hyperalgesia in a rat model of peripheral mononeuropathy. The journal of pain : official journal of the American Pain Society 20100201
Interaction of benzopyranone derivatives and related compounds with human concentrative nucleoside transporters 1, 2 and 3 heterologously expressed in porcine PK15 nucleoside transporter deficient cells. Structure-activity relationships and determinants of transporter affinity and selectivity. Biochemical pharmacology 20100201
The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugs. American journal of physiology. Gastrointestinal and liver physiology 20100201
The impact of serine/threonine phosphorylation in Staphylococcus aureus. International journal of medical microbiology : IJMM 20100201
Interferon as an alternative to purine analogues in the treatment of hairy cell leukaemia. British journal of haematology 20100201
Acidic residues in the purine binding site govern the 6-oxopurine specificity of the Leishmania donovani xanthine phosphoribosyltransferase. The international journal of biochemistry & cell biology 20100201
Xanthine dehydrogenase AtXDH1 from Arabidopsis thaliana is a potent producer of superoxide anions via its NADH oxidase activity. Plant molecular biology 20100201
Effects of some modulators on purine nucleoside phosphorylase activity in myocardial tissue. Scandinavian journal of clinical and laboratory investigation 20100201
Pediatric neurological syndromes and inborn errors of purine metabolism. Neurochemistry international 20100201
Synthesis and evaluation of two series of 4'-aza-carbocyclic nucleosides as adenosine A2A receptor agonists. Bioorganic & medicinal chemistry letters 20100201
Natural and artificial RNAs occupy the same restricted region of sequence space. RNA (New York, N.Y.) 20100201
Study of inborn errors of metabolism in urine from patients with unexplained mental retardation. Journal of inherited metabolic disease 20100201
Metabolomics in angiotensin II-induced cardiac hypertrophy. Hypertension (Dallas, Tex. : 1979) 20100201
Experimental vaccination of sheep and cattle against tick infestation using recombinant 5'-nucleotidase. Parasite immunology 20100201
Rapid measurements of 2,8-dihydroxyadenine (2,8-DHA) with a nanostructured electrochemical sensor in 5-fold diluted supernatants of endothelial cells exposed to oxidative stress. The Analyst 20100201
Effect of Saccharomyces cerevisiae fermentation product on ruminal fermentation and nutrient utilization in dairy cows. Journal of dairy science 20100201
Association of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) with uric acid among adults with elevated community exposure to PFOA. Environmental health perspectives 20100201
Structure of grouper iridovirus purine nucleoside phosphorylase. Acta crystallographica. Section D, Biological crystallography 20100201
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic study of the putative SAICAR synthetase (PH0239) from Pyrococcus horikoshii OT3. Acta crystallographica. Section F, Structural biology and crystallization communications 20100201
mRNA secondary structures fold sequentially but exchange rapidly in vivo. PLoS biology 20100201
A novel role for Arabidopsis mitochondrial ABC transporter ATM3 in molybdenum cofactor biosynthesis. The Plant cell 20100201
Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease. PLoS genetics 20100201
Genome sequence of the pea aphid Acyrthosiphon pisum. PLoS biology 20100201
Decoupling Environment-Dependent and Independent Genetic Robustness across Bacterial Species. PLoS computational biology 20100201
Interpreting metabolomic profiles using unbiased pathway models. PLoS computational biology 20100201
Design and synthesis of 3'-fluoropenciclovir analogues as antiviral agents. Archives of pharmacal research 20100201
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Mucosal healing and anti TNFs in IBD. Current drug targets 20100201
Progressive multifocal leukoencephalopathy in chronic lymphocytic leukemia: a report of three cases and review of the literature. Clinical lymphoma, myeloma & leukemia 20100201
[Molecular cloning, gene expression and characterization of purine nucleoside phosphorylase from Pseudoalteromonas sp. XM2107]. Wei sheng wu xue bao = Acta microbiologica Sinica 20100201
Current developments in intraspinal agents for cancer and noncancer pain. Current pain and headache reports 20100201
Microwave-assisted syntheses of nucleosides and their precursors. Future medicinal chemistry 20100201
6-Amino-9H-purine-1,7-diium bis-(4-methyl-benzene-sulfonate) monohydrate. Acta crystallographica. Section E, Structure reports online 20100201
Application of the dipeptidyl peptidase IV (DPPIV/CD26) based prodrug approach to different amine-containing drugs. Journal of medicinal chemistry 20100128
A comparative study on conformation and ligand binding of the neuronal uncoupling proteins. Biochemistry 20100126
Theoretical study of the mechanism of inhibition of xanthine oxidase by flavonoids and gallic acid derivatives. The journal of physical chemistry. B 20100121
Glycosidase inhibition: assessing mimicry of the transition state. Organic & biomolecular chemistry 20100121
Dynamics of ultrafast singlet and triplet charge transfer in anthraquinone-DNA conjugates. Journal of the American Chemical Society 20100120
Molecular dynamics and quantum mechanics of RNA: conformational and chemical change we can believe in. Accounts of chemical research 20100119
Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells. British journal of cancer 20100119
Altering the spectrum of immunoglobulin V gene somatic hypermutation by modifying the active site of AID. The Journal of experimental medicine 20100118
Sensing purine nucleoside phosphorylase activity by using silver nanoparticles. Biosensors & bioelectronics 20100115
Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms. Human molecular genetics 20100115
Crystal structure of the ATPPase subunit and its substrate-dependent association with the GATase subunit: a novel regulatory mechanism for a two-subunit-type GMP synthetase from Pyrococcus horikoshii OT3. Journal of molecular biology 20100115
Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-alpha: Hit to lead studies. Bioorganic & medicinal chemistry letters 20100115
Identification and optimization of inhibitors of Trypanosomal cysteine proteases: cruzain, rhodesain, and TbCatB. Journal of medicinal chemistry 20100114
Structure-based design of pteridine reductase inhibitors targeting African sleeping sickness and the leishmaniases. Journal of medicinal chemistry 20100114
9-Arylpurines as a novel class of enterovirus inhibitors. Journal of medicinal chemistry 20100114
Effects of bioconjugation on the structures and electronic spectra of CdSe: density functional theory study of CdSe-adenine complexes. The journal of physical chemistry. B 20100114
Heat shock protein 90: inhibitors in clinical trials. Journal of medicinal chemistry 20100114
Fructose-1,6-bisphosphatase Inhibitors. 2. Design, synthesis, and structure-activity relationship of a series of phosphonic acid containing benzimidazoles that function as 5'-adenosinemonophosphate (AMP) mimics. Journal of medicinal chemistry 20100114
Overexpressed proteins may act as mops removing their ligands from the host cells: a case study of calf PNP. Biochemical and biophysical research communications 20100108
How I treat hairy cell leukemia. Blood 20100107
Novel extreme homozygote haplotypes at the human caveolin 1 gene upstream purine complex in sporadic Alzheimer's disease. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20100105
[Chorea-acanthocytosis without acanthocytes]. Revue neurologique 20100101
Axons and astrocytes release ATP and glutamate to evoke calcium signals in NG2-glia. Glia 20100101
Ectophosphodiesterase/nucleotide phosphohydrolase (Enpp) nucleotidases: cloning, conservation and developmental restriction. The International journal of developmental biology 20100101
Effects of allopurinol on uric acid concentrations, xanthine oxidoreductase activity and oxidative stress in broiler chickens. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100101
Deficiency of the housekeeping gene hypoxanthine-guanine phosphoribosyltransferase (HPRT) dysregulates neurogenesis. Molecular therapy : the journal of the American Society of Gene Therapy 20100101
Effects of growth conditions on biofilm formation by Actinobacillus pleuropneumoniae. Veterinary research 20100101
Mutations in the Salmonella enterica serovar Choleraesuis cAMP-receptor protein gene lead to functional defects in the SPI-1 Type III secretion system. Veterinary research 20100101
Genotoxicity studies of organically grown broccoli (Brassica oleracea var. italica) and its interactions with urethane, methyl methanesulfonate and 4-nitroquinoline-1-oxide genotoxicity in the wing spot test of Drosophila melanogaster. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Isotope labeling strategies for NMR studies of RNA. Journal of biomolecular NMR 20100101
Transport of purines and purine salvage pathway inhibitors by the Plasmodium falciparum equilibrative nucleoside transporter PfENT1. Molecular and biochemical parasitology 20100101
Isolation of an oxalate-resistant Ashbya gossypii strain and its improved riboflavin production. Journal of industrial microbiology & biotechnology 20100101
Effect of xanthine oxidase-generated extracellular superoxide on skeletal muscle force generation. American journal of physiology. Regulatory, integrative and comparative physiology 20100101
The role of chemotherapy and radiation in the treatment of locally advanced non-small cell lung cancer (NSCLC). Current drug targets 20100101
Predictive markers for haematological toxicity of pemetrexed. Current drug targets 20100101
Allium sativum L. extract prevents methyl mercury-induced cytotoxicity in peripheral blood leukocytes (LS). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Roscovitine binds to novel L-channel (CaV1.2) sites that separately affect activation and inactivation. The Journal of biological chemistry 20100101
Monocyclic aromatic amines as potential human carcinogens: old is new again. Carcinogenesis 20100101
Structural analysis of DFG-in and DFG-out dual Src-Abl inhibitors sharing a common vinyl purine template. Chemical biology & drug design 20100101
Specific chemotherapy of Chagas disease: relevance, current limitations and new approaches. Acta tropica 20100101
Biomolecular response of oxanine in DNA strands to T4 polynucleotide kinase, T4 DNA ligase, and restriction enzymes. Biochemical and biophysical research communications 20100101
R-roscovitine (Seliciclib) affects CLL cells more strongly than combinations of fludarabine or cladribine with cyclophosphamide: Inhibition of CDK7 sensitizes leukemic cells to caspase-dependent apoptosis. Journal of cellular biochemistry 20100101
Ureide catabolism in Arabidopsis thaliana and Escherichia coli. Nature chemical biology 20100101
15N and 13C NMR chemical shifts of 6-(fluoro, chloro, bromo, and iodo)purine 2'-deoxynucleosides: measurements and calculations. Magnetic resonance in chemistry : MRC 20100101
The effects of extracellular nucleotides on [Ca2+]i signalling in a human-derived renal proximal tubular cell line (HKC-8). Journal of cellular biochemistry 20100101
The role of Bacillus anthracis germinant receptors in germination and virulence. Molecular microbiology 20100101
1.45 A resolution crystal structure of recombinant PNP in complex with a pM multisubstrate analogue inhibitor bearing one feature of the postulated transition state. Biochemical and biophysical research communications 20100101
Synthesis and evaluation of 3'-azido-2',3'-dideoxypurine nucleosides as inhibitors of human immunodeficiency virus. Bioorganic & medicinal chemistry letters 20100101
Protein expression profiling of primary mammary epithelial cells derived from MMTV-neu mice revealed that HER2/NEU-driven changes in protein expression are functionally clustered. IUBMB life 20100101
Inhibition of CTP synthase from Escherichia coli by xanthines and uric acids. Bioorganic & medicinal chemistry letters 20100101
Chagas disease: progress and new perspectives. Current medicinal chemistry 20100101
Mitochondrial uncoupling proteins in unicellular eukaryotes. Biochimica et biophysica acta 20100101
Intermediate uveitis. Indian journal of ophthalmology 20100101
Computational study of the interactions between guanine derivatives and cyclin-dependent kinase 2 (CDK2) by CoMFA and QM/MM. Journal of chemical information and modeling 20100101
Aminothiols and allantoin in chronic dialysis patients: effects of hemodialysis sessions. Clinical nephrology 20100101
Histological and genetic markers for non-small-cell lung cancer: customizing treatment based on individual tumor biology. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100101
Which role for rituximab in hairy cell leukemia? Reflections on six cases. Acta haematologica 20100101
Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach. PLoS computational biology 20100101
Snake mitochondrial genomes: phylogenetic relationships and implications of extended taxon sampling for interpretations of mitogenomic evolution. BMC genomics 20100101
Malondialdehyde-deoxyguanosine adducts among workers of a Thai industrial estate and nearby residents. Environmental health perspectives 20100101
Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni. Acta crystallographica. Section D, Biological crystallography 20100101
Glutamate, aspartate and nucleotide transporters in the SLC17 family form four main phylogenetic clusters: evolution and tissue expression. BMC genomics 20100101
Temperature increase prevails over acidification in gene expression modulation of amastigote differentiation in Leishmania infantum. BMC genomics 20100101
[Vesicular ATP transporter: a missing link of purinergic chemical transmission]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20100101
Control of ATP homeostasis during the respiro-fermentative transition in yeast. Molecular systems biology 20100101
Unbiased transcriptional comparisons of generalist and specialist herbivores feeding on progressively defenseless Nicotiana attenuata plants. PloS one 20100101
Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation. Neural development 20100101
Remobilization of Tol2 transposons in Xenopus tropicalis. BMC developmental biology 20100101
Exocytosis and protein secretion in Trypanosoma. BMC microbiology 20100101
Transcriptome analysis reveals absence of unintended effects in drought-tolerant transgenic plants overexpressing the transcription factor ABF3. BMC genomics 20100101
Two chitinase-like proteins abundantly accumulated in latex of mulberry show insecticidal activity. BMC biochemistry 20100101
Expressed Alu repeats as a novel, reliable tool for normalization of real-time quantitative RT-PCR data. Genome biology 20100101
Allosteric regulation of HIV-1 reverse transcriptase by ATP for nucleotide selection. PloS one 20100101
Uptake of purines in Plasmodium falciparum-infected human erythrocytes is mostly mediated by the human equilibrative nucleoside transporter and the human facilitative nucleobase transporter. Malaria journal 20100101
Global transcriptomic response of Leptospira interrogans serovar Copenhageni upon exposure to serum. BMC microbiology 20100101
Using genomic signatures for HIV-1 sub-typing. BMC bioinformatics 20100101
U87MG decoded: the genomic sequence of a cytogenetically aberrant human cancer cell line. PLoS genetics 20100101
Identification of trkH, encoding a potassium uptake protein required for Francisella tularensis systemic dissemination in mice. PloS one 20100101
The Mrs1 splicing factor binds the bI3 group I intron at each of two tetraloop-receptor motifs. PloS one 20100101
The genome sequence of the rumen methanogen Methanobrevibacter ruminantium reveals new possibilities for controlling ruminant methane emissions. PloS one 20100101
Comprehensive identification and modified-site mapping of S-nitrosylated targets in prostate epithelial cells. PloS one 20100101
Biochemical characterization of three putative ATPases from a new type IV secretion system of Aeromonas veronii plasmid pAC3249A. BMC biochemistry 20100101
NSC114792, a novel small molecule identified through structure-based computational database screening, selectively inhibits JAK3. Molecular cancer 20100101
Synthetic biology: tools to design, build, and optimize cellular processes. Journal of biomedicine & biotechnology 20100101
Expression and functional activity of nucleoside transporters in human choroid plexus. Cerebrospinal fluid research 20100101
The Bcl-2 family as a rational target for the treatment of B-cell chronic lymphocytic leukaemia. Current medicinal chemistry 20100101
Transposon identification using profile HMMs. BMC genomics 20100101
Role of the gerP operon in germination and outgrowth of Bacillus anthracis spores. PloS one 20100101
Blood lipids, homocysteine, stress factors, and vitamins in clinically stable multiple sclerosis patients. Lipids in health and disease 20100101
Potential and perspectives of cyclonucleosides. Current medicinal chemistry 20100101
Functional characterization of Arabidopsis thaliana transthyretin-like protein. BMC plant biology 20100101
Cloning, purification, and partial characterization of Bacillus subtilis urate oxidase expressed in Escherichia coli. Journal of biomedicine & biotechnology 20100101
Management of hyperuricemia in gout: focus on febuxostat. Clinical interventions in aging 20100101
Alterations in adenosine metabolism and signaling in patients with chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis. PloS one 20100101
Mycophenolate mofetil-related gastrointestinal mucosal injury in multivisceral transplantation. Transplantation proceedings 20100101
NAD+ metabolite levels as a function of vitamins and calorie restriction: evidence for different mechanisms of longevity. BMC chemical biology 20100101
Expression profiling of mouse embryonic fibroblasts with a deletion in the helicase domain of the Werner Syndrome gene homologue treated with hydrogen peroxide. BMC genomics 20100101
Identification of hypoxanthine as a urine marker for non-Hodgkin lymphoma by low-mass-ion profiling. BMC cancer 20100101
Evolutionary history of anglerfishes (Teleostei: Lophiiformes): a mitogenomic perspective. BMC evolutionary biology 20100101
Expression, purification, and initial characterization of different domains of recombinant mouse 2',3'-cyclic nucleotide 3'-phosphodiesterase, an enigmatic enzyme from the myelin sheath. BMC research notes 20100101
Free energy estimation of short DNA duplex hybridizations. BMC bioinformatics 20100101
Immunobiology of African trypanosomes: need of alternative interventions. Journal of biomedicine & biotechnology 20100101
Identification of functional modules that correlate with phenotypic difference: the influence of network topology. Genome biology 20100101
Renal secretion of uric acid by organic anion transporter 2 (OAT2/SLC22A7) in human. Biological & pharmaceutical bulletin 20100101
Lack of association between dietary fructose and hyperuricemia risk in adults. Nutrition & metabolism 20100101
Bioimaging of nucleolin aptamer-containing 5-(N-benzylcarboxyamide)-2'-deoxyuridine more capable of specific binding to targets in cancer cells. Journal of biomedicine & biotechnology 20100101
Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia. PloS one 20100101
Global self-regulation of the cellular metabolic structure. PloS one 20100101
Characterization of the octamer, a cis-regulatory element that modulates excretory cell gene-expression in Caenorhabditis elegans. BMC molecular biology 20100101
Treatment rationale and study design for a phase III, double-blind, placebo-controlled study of maintenance pemetrexed plus best supportive care versus best supportive care immediately following induction treatment with pemetrexed plus cisplatin for advanced nonsquamous non-small cell lung cancer. BMC cancer 20100101
Plasticity of the mitoproteome to nitrogen sources (nitrate and ammonium) in Chlamydomonas reinhardtii: the logic of Aox1 gene localization. Biochimica et biophysica acta 20100101
Depletion of the non-coding regulatory 6S RNA in E. coli causes a surprising reduction in the expression of the translation machinery. BMC genomics 20100101
Genome-wide functional analysis of human 5' untranslated region introns. Genome biology 20100101
Assessment of peripheral blood and bone marrow cells apoptosis caused by purine analogues in patients with chronic lymphocytic leukemia in correlation with parameters of disease progression. Acta haematologica 20100101
Investigating a new generation of ribozymes in order to target HCV. PloS one 20100101
A search for Trypanosoma brucei rhodesiense diagnostic antigens by proteomic screening and targeted cloning. PloS one 20100101
Comparative genomics reveals 104 candidate structured RNAs from bacteria, archaea, and their metagenomes. Genome biology 20100101
Basal core promoters control the equilibrium between negative cofactor 2 and preinitiation complexes in human cells. Genome biology 20100101
Phylogenetic analysis of fungal ABC transporters. BMC genomics 20100101
Forced unbinding of GPR17 ligands from wild type and R255I mutant receptor models through a computational approach. BMC structural biology 20100101
Valganciclovir in the treatment of cytomegalovirus retinitis in HIV-infected patients. Clinical ophthalmology (Auckland, N.Z.) 20100101
Abacavir/lamivudine combination in the treatment of HIV: a review. Therapeutics and clinical risk management 20100101
The pea aphid genome sequence brings theories of insect defense into question. Genome biology 20100101
Proteome differences associated with fat accumulation in bovine subcutaneous adipose tissues. Proteome science 20100101
Aptamer antagonists of myelin-derived inhibitors promote axon growth. PloS one 20100101
Evolutionary constraints acting on DDX3X protein potentially interferes with Rev-mediated nuclear export of HIV-1 RNA. PloS one 20100101
[The effect of red pigment on amyloidization of yeast proteins]. Tsitologiia 20100101
Genome-scale metabolic analysis of Clostridium thermocellum for bioethanol production. BMC systems biology 20100101
An overview on nucleases (DNase, RNase, and phosphodiesterase) in snake venoms. Biochemistry. Biokhimiia 20100101
An ab initio and AIM investigation into the hydration of 2-thioxanthine. Chemistry Central journal 20100101
Bacteria in cancer therapy: a novel experimental strategy. Journal of biomedical science 20100101
Efficient activation of reconstructed rat embryos by cyclin-dependent kinase inhibitors. PloS one 20100101
Inhibition of human immunodeficiency virus type-1 by cdk inhibitors. AIDS research and therapy 20100101
Microglia in the aging brain: relevance to neurodegeneration. Molecular neurodegeneration 20100101
The complete multipartite genome sequence of Cupriavidus necator JMP134, a versatile pollutant degrader. PloS one 20100101
Adaptation of group A Streptococcus to human amniotic fluid. PloS one 20100101
Abundant oligonucleotides common to most bacteria. PloS one 20100101
Comparative genomics of metabolic networks of free-living and parasitic eukaryotes. BMC genomics 20100101
Multiconstrained gene clustering based on generalized projections. BMC bioinformatics 20100101
Specificity and functionality of microRNA inhibitors. Silence 20100101
A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death. ASN neuro 20100101
Empirical evaluation of oligonucleotide probe selection for DNA microarrays. PloS one 20100101
The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial. Arthritis research & therapy 20100101
Platelet function and Isoprostane biology. Should isoprostanes be the newest member of the orphan-ligand family? Journal of biomedical science 20100101
Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. PloS one 20100101
The transition from noncoded to coded protein synthesis: did coding mRNAs arise from stability-enhancing binding partners to tRNA? Biology direct 20100101
PGC-1alpha down-regulation affects the antioxidant response in Friedreich's ataxia. PloS one 20100101
Plasmodium falciparum spermidine synthase inhibition results in unique perturbation-specific effects observed on transcript, protein and metabolite levels. BMC genomics 20100101
Thioredoxin and glutathione systems differ in parasitic and free-living platyhelminths. BMC genomics 20100101
Biology-driven cancer drug development: back to the future. BMC biology 20100101
Antiviral activity and tolerability of amdoxovir with zidovudine in a randomized double-blind placebo-controlled study in HIV-1-infected individuals. Antiviral therapy 20100101
Soluble amyloid-beta, effect on cerebral arteriolar regulation and vascular cells. Molecular neurodegeneration 20100101
Natural occurrence of 2',5'-linked heteronucleotides in marine sponges. Marine drugs 20100101
Regulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophages. Mediators of inflammation 20100101
Gi- and Gq-coupled ADP (P2Y) receptors act in opposition to modulate nociceptive signaling and inflammatory pain behavior. Molecular pain 20100101
Genetic polymorphisms of MDM2 and TP53 genes are associated with risk of nasopharyngeal carcinoma in a Chinese population. BMC cancer 20100101
Properties and identification of antibiotic drug targets. BMC bioinformatics 20100101
Hyperuricaemia and the metabolic syndrome in type 2 DM. Diabetology & metabolic syndrome 20100101
Primary metabolism in Lactobacillus sakei food isolates by proteomic analysis. BMC microbiology 20100101
Comparison of Metabolic Risk Factors in Urolithiasis Patients according to Family History. Korean journal of urology 20100101
Adenine oxidation by pyrite-generated hydroxyl radicals. Geochemical transactions 20100101
Differences in transcription between free-living and CO2-activated third-stage larvae of Haemonchus contortus. BMC genomics 20100101
Risks vs benefits of glatiramer acetate: a changing perspective as new therapies emerge for multiple sclerosis. Therapeutics and clinical risk management 20100101
The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compound. PloS one 20100101
Pemetrexed plus cisplatin/carboplatin in previously treated locally advanced or metastatic non-small cell lung cancer patients. Journal of experimental & clinical cancer research : CR 20100101
Challenges in the frontline treatment of patients with chronic lymphocytic leukemia. Current hematologic malignancy reports 20100101
Delayed presentation of severe combined immunodeficiency due to prolonged maternal T cell engraftment. Annals of Saudi medicine 20100101
Fludarabine-induced bradycardia in a patient with refractory leukemia. Annals of Saudi medicine 20100101
Large scale analysis of positional effects of single-base mismatches on microarray gene expression data. BioData mining 20100101
Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution. Biology direct 20100101
Differential control of Notch1 gene transcription by Klf4 and Sp3 transcription factors in normal versus cancer-derived keratinocytes. PloS one 20100101
Changes in Adenylate Nucleotides Concentration and Na, K-ATPase Activities in Erythrocytes of Horses in Function of Breed and Sex. Veterinary medicine international 20100101
Transcript profiling of common bean (Phaseolus vulgaris L.) using the GeneChip Soybean Genome Array: optimizing analysis by masking biased probes. BMC plant biology 20100101
Analysis of gene evolution and metabolic pathways using the Candida Gene Order Browser. BMC genomics 20100101
Transcriptome analysis of porcine PBMCs after in vitro stimulation by LPS or PMA/ionomycin using an expression array targeting the pig immune response. BMC genomics 20100101
Nucleosome rotational setting is associated with transcriptional regulation in promoters of tissue-specific human genes. Genome biology 20100101
Massively parallel pyrosequencing-based transcriptome analyses of small brown planthopper (Laodelphax striatellus), a vector insect transmitting rice stripe virus (RSV). BMC genomics 20100101
Clinical experience in T cell deficient patients. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20100101
An overview of Cdk1-controlled targets and processes. Cell division 20100101
Expression for caffeine biosynthesis and related enzymes in Camellia sinensis. Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101
Antisense DNA parameters derived from next-nearest-neighbor analysis of experimental data. BMC bioinformatics 20100101
Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis. BMC systems biology 20100101
GC3 biology in corn, rice, sorghum and other grasses. BMC genomics 20100101
Factors affecting the long-term response to tacrolimus in renal transplant patients: pharmacokinetic and pharmacogenetic approach. International journal of medical sciences 20100101
Biosynthesis and molecular genetics of polyketides in marine dinoflagellates. Marine drugs 20100101
[The clinical diagnostic value of a study of the activity of enzymes of the guanyl branch of purine metabolism in patients with ankylosing spondyloarthritis]. Terapevticheskii arkhiv 20100101
Carbon metabolism of enterobacterial human pathogens growing in epithelial colorectal adenocarcinoma (Caco-2) cells. PloS one 20100101
Determination of genes and microRNAs involved in the resistance to fludarabine in vivo in chronic lymphocytic leukemia. Molecular cancer 20100101
Inhibitors of the Purine Salvage Pathway: A Valuable Approach for Antiprotozoal Chemotherapy? Current medicinal chemistry 20100101
Glucose sensing in the pancreatic beta cell: a computational systems analysis. Theoretical biology & medical modelling 20100101
Removal of urothelium affects bladder contractility and release of ATP but not release of NO in rat urinary bladder. BMC urology 20100101
Why functional pre-erythrocytic and bloodstage malaria vaccines fail: a meta-analysis of fully protective immunizations and novel immunological model. PloS one 20100101
Nucleoside drugs induce cellular differentiation by caspase-dependent degradation of stem cell factors. PloS one 20100101
MicroRNAs involvement in fludarabine refractory chronic lymphocytic leukemia. Molecular cancer 20100101
Cartography of methicillin-resistant S. aureus transcripts: detection, orientation and temporal expression during growth phase and stress conditions. PloS one 20100101
Comparative Global Gene Expression Profiles of Wild-Type Yersinia pestis CO92 and Its Braun Lipoprotein Mutant at Flea and Human Body Temperatures. Comparative and functional genomics 20100101
Association analysis of retinoic acid receptor beta (RARbeta) gene with high myopia in Chinese subjects. Molecular vision 20100101
Do anticodons of misacylated tRNAs preferentially mismatch codons coding for the misloaded amino acid? BMC molecular biology 20100101
Revealing fosfomycin primary effect on Staphylococcus aureus transcriptome: modulation of cell envelope biosynthesis and phosphoenolpyruvate induced starvation. BMC microbiology 20100101
A framework for classification of prokaryotic protein kinases. PloS one 20100101
The role of transposable elements in the evolution of non-mammalian vertebrates and invertebrates. Genome biology 20100101
Proteomic analysis of the fish pathogen Flavobacterium columnare. Proteome science 20100101
Active site plasticity revealed from the structure of the enterobacterial N-ribohydrolase RihA bound to a competitive inhibitor. BMC structural biology 20100101
Global transcriptional analysis of Bacillus licheniformis reveals an overlap between heat shock and iron limitation stimulon. Journal of molecular microbiology and biotechnology 20100101
The Waddlia genome: a window into chlamydial biology. PloS one 20100101
Native aggregation as a cause of origin of temporary cellular structures needed for all forms of cellular activity, signaling and transformations. Theoretical biology & medical modelling 20100101
A novel chemogenomics analysis of G protein-coupled receptors (GPCRs) and their ligands: a potential strategy for receptor de-orphanization. BMC bioinformatics 20100101
Drawing the line between commensal and pathogenic Gardnerella vaginalis through genome analysis and virulence studies. BMC genomics 20100101
Regulation of hemolysin expression and virulence of Staphylococcus aureus by a serine/threonine kinase and phosphatase. PloS one 20100101
Defective lamin A-Rb signaling in Hutchinson-Gilford Progeria Syndrome and reversal by farnesyltransferase inhibition. PloS one 20100101
[Effect utilize of food biologically active additive on base the lipid marine hydrobions under experimental cardiovascular pathology rats]. Voprosy pitaniia 20100101
Synthesis of some novel hydrazono acyclic nucleoside analogues. Beilstein journal of organic chemistry 20100101
Innate immune recognition and activation during HIV infection. Retrovirology 20100101
Absence of functional TolC protein causes increased stress response gene expression in Sinorhizobium meliloti. BMC microbiology 20100101
De novo characterization of a whitefly transcriptome and analysis of its gene expression during development. BMC genomics 20100101
Functional and molecular effects of arginine butyrate and prednisone on muscle and heart in the mdx mouse model of Duchenne Muscular Dystrophy. PloS one 20100101
Deletion of P2X2 and P2X3 receptor subunits does not alter motility of the mouse colon. Frontiers in neuroscience 20100101
Radiolabeled nucleoside analogues for PET imaging of HSV1-tk gene expression. Current topics in medicinal chemistry 20100101
Bronchus-associated lymphoid tissue (BALT) and survival in a vaccine mouse model of tularemia. PloS one 20100101
Inborn errors of energy metabolism associated with myopathies. Journal of biomedicine & biotechnology 20100101
Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo. Journal of experimental & clinical cancer research : CR 20100101
Management of ANCA-associated vasculitis: Current trends and future prospects. Therapeutics and clinical risk management 20100101
Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PloS one 20100101
Patterns of nucleotides that flank substitutions in human orthologous genes. BMC genomics 20100101
Synergistic properties of methylxanthine with cadmium and mercury on dermatophytes. Journal of global infectious diseases 20100101
Combining next-generation sequencing strategies for rapid molecular resource development from an invasive aphid species, Aphis glycines. PloS one 20100101
Different integration site structures between L1 protein-mediated retrotransposition in cis and retrotransposition in trans. Mobile DNA 20100101
First-line treatment of chronic lymphocytic leukemia: role of alemtuzumab. OncoTargets and therapy 20100101
A single sequence context cannot satisfy all non-AUG initiator codons in yeast. BMC microbiology 20100101
Features of recent codon evolution: a comparative polymorphism-fixation study. Journal of biomedicine & biotechnology 20100101
Mining non-model genomic libraries for microsatellites: BAC versus EST libraries and the generation of allelic richness. BMC genomics 20100101
A metabolic model of human erythrocytes: practical application of the E-Cell Simulation Environment. Journal of biomedicine & biotechnology 20100101
Ribavirin for Crimean-Congo hemorrhagic fever: systematic review and meta-analysis. BMC infectious diseases 20100101
Hsp90 as a gatekeeper of tumor angiogenesis: clinical promise and potential pitfalls. Journal of oncology 20100101
Predicting functional associations from metabolism using bi-partite network algorithms. BMC systems biology 20100101
Use of clofarabine for acute childhood leukemia. Biologics : targets & therapy 20100101
'Lantern-Shaped' Platinum(III) Complexes with Axially Bound 9-Ethylguanine or 1-Methylcytosine (L) of General Formula [Pt(2){HN=C(Bu)O}(4)L(2)](NO(3))(2). Bioinorganic chemistry and applications 20100101
Molecular Architectures Derived from Metal Ions and the Flexible 3,3'-Bipyridine Ligand: Unexpected Dimer with Hg(II). Bioinorganic chemistry and applications 20100101
Synthesis and Characterization of Novel Ruthenium(III) Complexes with Histamine. Bioinorganic chemistry and applications 20100101
Identification and characterization of full-length cDNAs in channel catfish (Ictalurus punctatus) and blue catfish (Ictalurus furcatus). PloS one 20100101
High serum uric acid increases the risk for nonalcoholic Fatty liver disease: a prospective observational study. PloS one 20100101
Comparison of koala LPCoLN and human strains of Chlamydia pneumoniae highlights extended genetic diversity in the species. BMC genomics 20100101
Over-expression of adenosine deaminase in mouse podocytes does not reverse puromycin aminonucleoside resistance. BMC nephrology 20100101
Two origins for the gene encoding alpha-isopropylmalate synthase in fungi. PloS one 20100101
Characterization of a Clp protease gene regulator and the reaeration response in Mycobacterium tuberculosis. PloS one 20100101
Exercise-induced changes in renal URAT1 activity and expression in rats. Renal failure 20100101
Omic data from evolved E. coli are consistent with computed optimal growth from genome-scale models. Molecular systems biology 20100101
Differential gene expression profile of retinoblastoma compared to normal retina. Molecular vision 20100101
Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profiling. Genome medicine 20100101
What is a microsatellite: a computational and experimental definition based upon repeat mutational behavior at A/T and GT/AC repeats. Genome biology and evolution 20100101
Microarray analysis of response of Salmonella during infection of HLA-B27- transfected human macrophage-like U937 cells. BMC genomics 20100101
The effect of stereochemistry on sodium ion complexation in nucleoside-metallacarborane conjugates. Bioinorganic chemistry and applications 20100101
Archaea signal recognition particle shows the way. Archaea (Vancouver, B.C.) 20100101
Extracting the abstraction pyramid from complex networks. BMC bioinformatics 20100101
R-Roscovitine (Seliciclib) prevents DNA damage-induced cyclin A1 upregulation and hinders non-homologous end-joining (NHEJ) DNA repair. Molecular cancer 20100101
Biochemical and anatomical substrates of depression and sickness behavior. The Israel journal of psychiatry and related sciences 20100101
Identification of targets and new developments in the treatment of multiple sclerosis--focus on cladribine. Drug design, development and therapy 20100101
The effect of leflunomide on cycling and activation of T-cells in HIV-1-infected participants. PloS one 20100101
The early asthmatic response is associated with glycolysis, calcium binding and mitochondria activity as revealed by proteomic analysis in rats. Respiratory research 20100101
Pathophysiological roles for purines: adenosine, caffeine and urate. Progress in brain research 20100101
Ranked retrieval of Computational Biology models. BMC bioinformatics 20100101
Transcription profiling of Epstein-Barr virus nuclear antigen (EBNA)-1 expressing cells suggests targeting of chromatin remodeling complexes. PloS one 20100101
The Mutyh base excision repair gene influences the inflammatory response in a mouse model of ulcerative colitis. PloS one 20100101
Acute, multiple-dose dermal and genetic toxicity of Nu-3: a novel antimicrobial agent. Journal of biomedicine & biotechnology 20100101
Exercise stress testing in children with metabolic or neuromuscular disorders. International journal of pediatrics 20100101
Homologous illegitimate random integration of foreign DNA into the X chromosome of a transgenic mouse line. BMC molecular biology 20100101
Neurotoxic alkaloids: saxitoxin and its analogs. Marine drugs 20100101
Forever young: mechanisms of natural anoxia tolerance and potential links to longevity. Oxidative medicine and cellular longevity 20100101
In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells. BMC cancer 20100101
Codon usage bias and the evolution of influenza A viruses. Codon Usage Biases of Influenza Virus. BMC evolutionary biology 20100101
DNA mismatch repair in eukaryotes and bacteria. Journal of nucleic acids 20100101
DNA-Destabilizing Agents as an Alternative Approach for Targeting DNA: Mechanisms of Action and Cellular Consequences. Journal of nucleic acids 20100101
Structural determinants of photoreactivity of triplex forming oligonucleotides conjugated to psoralens. Journal of nucleic acids 20100101
Expression of the RNA-binding protein RBM3 is associated with a favourable prognosis and cisplatin sensitivity in epithelial ovarian cancer. Journal of translational medicine 20100101
Systems approach to investigating host-pathogen interactions in infections with the biothreat agent Francisella. Constraints-based model of Francisella tularensis. BMC systems biology 20100101
Digital expression profiling of novel diatom transcripts provides insight into their biological functions. Genome biology 20100101
Selective Incision of the alpha-N-Methyl-Formamidopyrimidine Anomer by Escherichia coli Endonuclease IV. Journal of nucleic acids 20100101
Pre-Steady-State Kinetic Analysis of Truncated and Full-Length Saccharomyces cerevisiae DNA Polymerase Eta. Journal of nucleic acids 20100101
The relation of coffee consumption to serum uric Acid in Japanese men and women aged 49-76 years. Journal of nutrition and metabolism 20100101
Structural properties of g,t-parallel duplexes. Journal of nucleic acids 20100101
Amino acid composition in endothermic vertebrates is biased in the same direction as in thermophilic prokaryotes. BMC evolutionary biology 20100101
Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysis. BMC systems biology 20100101
A transcriptomic approach highlights induction of secondary metabolism in citrus fruit in response to Penicillium digitatum infection. BMC plant biology 20100101
Cross-reactions between engineered xylose and galactose pathways in recombinant Saccharomyces cerevisiae. Biotechnology for biofuels 20100101
SOD1 Is Essential for the Viability of DT40 Cells and Nuclear SOD1 Functions as a Guardian of Genomic DNA. Journal of nucleic acids 20100101
Cellular responses to Cisplatin-induced DNA damage. Journal of nucleic acids 20100101
Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing. PloS one 20100101
Epigenetics of renal cell carcinoma: the path towards new diagnostics and therapeutics. Genome medicine 20100101
Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network. Molecular systems biology 20100101
HepatoNet1: a comprehensive metabolic reconstruction of the human hepatocyte for the analysis of liver physiology. Molecular systems biology 20100101
[Synthesis and biological properties of pyrimidine 4'-fluoro nucleosides and 4'-fluoro uridine 5'-O-triphospate]. Bioorganicheskaia khimiia 20100101
Topical ganciclovir in the treatment of acute herpetic keratitis. Clinical ophthalmology (Auckland, N.Z.) 20100101
A pipeline to determine RT-QPCR control genes for evolutionary studies: application to primate gene expression across multiple tissues. PloS one 20100101
Using evolutionary conserved modules in gene networks as a strategy to leverage high throughput gene expression queries. PloS one 20100101
Preservation of differentiation and clonogenic potential of human hematopoietic stem and progenitor cells during lyophilization and ambient storage. PloS one 20100101
GOPred: GO molecular function prediction by combined classifiers. PloS one 20100101
Analyzing the regulation of metabolic pathways in human breast cancer. BMC medical genomics 20100101
Brain architecture of the largest living land arthropod, the Giant Robber Crab Birgus latro (Crustacea, Anomura, Coenobitidae): evidence for a prominent central olfactory pathway? Frontiers in zoology 20100101
Improvement in medication education in a pediatric subspecialty practice. Pediatric rheumatology online journal 20100101
FATS is a transcriptional target of p53 and associated with antitumor activity. Molecular cancer 20100101
Metabolomic analysis in severe childhood pneumonia in the Gambia, West Africa: findings from a pilot study. PloS one 20100101
High-density expression of Ca2+-permeable ASIC1a channels in NG2 glia of rat hippocampus. PloS one 20100101
CPP-ZFN: a potential DNA-targeting anti-malarial drug. Malaria journal 20100101
Guanosine protects human neuroblastoma cells from oxidative stress and toxicity induced by Amyloid-beta peptide oligomers. Journal of biological regulators and homeostatic agents 20100101
MetNetGE: interactive views of biological networks and ontologies. BMC bioinformatics 20100101
Emerging oral treatments in multiple sclerosis - clinical utility of cladribine tablets. Therapeutics and clinical risk management 20100101
Temsirolimus in the treatment of relapsed or refractory mantle cell lymphoma. OncoTargets and therapy 20100101
Current and emerging therapies for the treatment of pancreatic cancer. OncoTargets and therapy 20100101
A proteomic view of Caenorhabditis elegans caused by short-term hypoxic stress. Proteome science 20100101
ModuleOrganizer: detecting modules in families of transposable elements. BMC bioinformatics 20100101
The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism. Journal of nucleic acids 20100101
Understanding the physiology of Lactobacillus plantarum at zero growth. Molecular systems biology 20100101
A phenomenological model for predicting melting temperatures of DNA sequences. PloS one 20100101
Polymorphisms in folate-metabolizing genes, chromosome damage, and risk of Down syndrome in Italian women: identification of key factors using artificial neural networks. BMC medical genomics 20100101
PPARs in Rhythmic Metabolic Regulation and Implications in Health and Disease. PPAR research 20100101
Elevated adenosine deaminase levels in celiac disease. Journal of clinical laboratory analysis 20100101
Asymmetric microarray data produces gene lists highly predictive of research literature on multiple cancer types. BMC bioinformatics 20100101
Coordination Reactions and Noncovalent Interactions of Polyamines with Nucleotides in Binary Systems and with Nucleotides and Copper(II) Ion in Ternary Systems. Bioinorganic chemistry and applications 20100101
USP7/HAUSP promotes the sequence-specific DNA binding activity of p53. PloS one 20100101
Flow cytometry and polymerase chain reaction-based analyses of minimal residual disease in chronic lymphocytic leukemia. Advances in hematology 20100101
[Clinico-pathogenetic significance of enzymes regulating nucleic metabolism in erythrocyte lysates and sera of patients with osteoarthrosis]. Klinicheskaia meditsina 20100101
Comparative transcriptional profiling of the limbal epithelial crypt demonstrates its putative stem cell niche characteristics. BMC genomics 20100101
SHMT1 1420 and MTHFR 677 variants are associated with rectal but not colon cancer. BMC cancer 20100101
Cloning and characterization of a novel alternatively spliced transcript of the human CHD7 putative helicase. BMC research notes 20100101
E. coli 6S RNA: a universal transcriptional regulator within the centre of growth adaptation. RNA biology 20100101
Predicting enzyme targets for cancer drugs by profiling human metabolic reactions in NCI-60 cell lines. BMC bioinformatics 20100101
Elevated Levels of DNA Strand Breaks Induced by a Base Analog in the Human Cell Line with the P32T ITPA Variant. Journal of nucleic acids 20100101
Effect of n3-methyladenine and an isosteric stable analogue on DNA polymerization. Journal of nucleic acids 20100101
Early Steps in the DNA Base Excision Repair Pathway of a Fission Yeast Schizosaccharomyces pombe. Journal of nucleic acids 20100101
Translesion synthesis polymerases in the prevention and promotion of carcinogenesis. Journal of nucleic acids 20100101
Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies. Journal of nucleic acids 20100101
Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence. BMC genomics 20100101
T-RFPred: a nucleotide sequence size prediction tool for microbial community description based on terminal-restriction fragment length polymorphism chromatograms. BMC microbiology 20100101
Mutational dynamics of murine angiogenin duplicates. BMC evolutionary biology 20100101
Deciphering the intracellular metabolism of Listeria monocytogenes by mutant screening and modelling. BMC genomics 20100101
Dose escalation study of an anti-thrombocytopenic agent in patients with chemotherapy induced thrombocytopenia. BMC cancer 20100101
Urine alkalization facilitates uric acid excretion. Nutrition journal 20100101
Modeling oncogenic signaling in colon tumors by multidirectional analyses of microarray data directed for maximization of analytical reliability. PloS one 20100101
Quantitative analysis of cellular metabolic dissipative, self-organized structures. International journal of molecular sciences 20100101
Potential short-term use of oral cladribine in treatment of relapsing-remitting multiple sclerosis. Neuropsychiatric disease and treatment 20100101
Molecular mechanisms of persistence of mutualistic bacteria Photorhabdus in the entomopathogenic nematode host. PloS one 20100101
Current and developing therapeutic agents in the treatment of Chagas disease. Drug design, development and therapy 20100101
Comparison of mitotic cell death by chromosome fragmentation to premature chromosome condensation. Molecular cytogenetics 20100101
Gene duplications in prokaryotes can be associated with environmental adaptation. BMC genomics 20100101
Antitumor activity against murine lymphoma L5178Y model of proteins from cacao (Theobroma cacao L.) seeds in relation with in vitro antioxidant activity. BMC complementary and alternative medicine 20100101
A QSAR study on some series of anti-hepatitis B virus (HBV) agents. Bioinformation 20100101
Bioreducible liposomes for gene delivery: from the formulation to the mechanism of action. PloS one 20100101
Error-Prone Translesion DNA Synthesis by Escherichia coli DNA Polymerase IV (DinB) on Templates Containing 1,2-dihydro-2-oxoadenine. Journal of nucleic acids 20100101
Insights into the structures of DNA damaged by hydroxyl radical: crystal structures of DNA duplexes containing 5-formyluracil. Journal of nucleic acids 20100101
The anti-myeloma activity of a novel purine scaffold HSP90 inhibitor PU-H71 is via inhibition of both HSP90A and HSP90B1. Journal of hematology & oncology 20100101
Evolutionary rates and gene dispensability associate with replication timing in the archaeon Sulfolobus islandicus. Genome biology and evolution 20100101
Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data. BMC cancer 20100101
Influence of wild-type MLL on glucocorticoid sensitivity and response to DNA-damage in pediatric acute lymphoblastic leukemia. Molecular cancer 20100101
Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems. Journal of nucleic acids 20100101
The effects of forodesine in murine and human multiple myeloma cells. Advances in hematology 20100101
Developmental pharmacogenetics in pediatric rheumatology: utilizing a new paradigm to effectively treat patients with juvenile idiopathic arthritis with methotrexate. Human genomics and proteomics : HGP 20100101
Candidate single nucleotide polymorphism markers for arsenic responsiveness of protein targets. Bioinformatics and biology insights 20100101
Lung cancer risk and genetic polymorphisms in DNA repair pathways: a meta-analysis. Journal of nucleic acids 20100101
Effects of mycophenolate mofetil on proliferation and mucin-5AC expression in human conjunctival goblet cells in vitro. Molecular vision 20100101
Circadian signatures in rat liver: from gene expression to pathways. BMC bioinformatics 20100101
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences. BMC bioinformatics 20100101
Mapping transcription mechanisms from multimodal genomic data. BMC bioinformatics 20100101
How does methotrexate suppress inflammation? Clinical and experimental rheumatology 20100101
Global protein interactome exploration through mining genome-scale data in Arabidopsis thaliana. BMC genomics 20100101
Antiproliferative and pro-apoptotic effects afforded by novel Src-kinase inhibitors in human neuroblastoma cells. BMC cancer 20100101
Effects of inosine on reperfusion injury after cardiopulmonary bypass. Journal of cardiothoracic surgery 20100101
Evaluation of suitable reference genes for normalization of real-time reverse transcription PCR analysis in colon cancer. Journal of experimental & clinical cancer research : CR 20100101
Modeling compositional dynamics based on GC and purine contents of protein-coding sequences. Biology direct 20100101
Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastoma. PloS one 20100101
A comparative analysis of gene-expression data of multiple cancer types. PloS one 20100101
Proteome of the phytopathogen Xanthomonas citri subsp. citri: a global expression profile. Proteome science 20100101
A genome-wide association scan on estrogen receptor-negative breast cancer. Breast cancer research : BCR 20100101
Syzygium cumini extract decrease adenosine deaminase, 5'nucleotidase activities and oxidative damage in platelets of diabetic patients. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20100101
Impact of the Staphylococcus epidermidis LytSR two-component regulatory system on murein hydrolase activity, pyruvate utilization and global transcriptional profile. BMC microbiology 20100101
DNA suspension arrays: silencing discrete artifacts for high-sensitivity applications. PloS one 20100101
Proteomic analysis of the dysferlin protein complex unveils its importance for sarcolemmal maintenance and integrity. PloS one 20100101
Insights into metazoan evolution from Alvinella pompejana cDNAs. BMC genomics 20100101
Effects of site-directed mutagenesis of mglA on motility and swarming of Myxococcus xanthus. BMC microbiology 20100101
Mycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesis. PloS one 20100101
Targeted metabolomics and mass spectrometry. Advances in protein chemistry and structural biology 20100101
A genomic perspective on the potential of Actinobacillus succinogenes for industrial succinate production. BMC genomics 20100101
Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast. Molecular systems biology 20100101
Factors influencing cerebral plasticity in the normal and injured brain. Frontiers in human neuroscience 20100101
The diagnosis of inherited metabolic diseases by microarray gene expression profiling. Orphanet journal of rare diseases 20100101
Molecular characterization of Borrelia persica, the agent of tick borne relapsing fever in Israel and the Palestinian Authority. PloS one 20100101
Post-transcriptional control by bacteriophage T4: mRNA decay and inhibition of translation initiation. Virology journal 20100101
Therapeutic activity of two xanthones in a xenograft murine model of human chronic lymphocytic leukemia. Journal of hematology & oncology 20100101
The antagonism between MCT-1 and p53 affects the tumorigenic outcomes. Molecular cancer 20100101
A garter snake transcriptome: pyrosequencing, de novo assembly, and sex-specific differences. BMC genomics 20100101
Recent N-atom containing compounds from indo-pacific invertebrates. Marine drugs 20100101
Comparative profiling of the transcriptional response to iron restriction in six serotypes of Actinobacillus pleuropneumoniae with different virulence potential. BMC genomics 20100101
Synthesis of phenolics and flavonoids in ginger (Zingiber officinale Roscoe) and their effects on photosynthesis rate. International journal of molecular sciences 20100101
Effect of oxidative damage due to excessive protein ingestion on pancreas function in mice. International journal of molecular sciences 20100101
Nelarabine in the treatment of refractory T-cell malignancies. Clinical Medicine Insights. Oncology 20100101
Complex and multidimensional lipid raft alterations in a murine model of Alzheimer's disease. International journal of Alzheimer's disease 20100101
Efficient gene targeting by homologous recombination in rat embryonic stem cells. PloS one 20100101
Removal of heterologous sequences from Plasmodium falciparum mutants using FLPe-recombinase. PloS one 20100101
Metabolic and transcriptomic responses of weaned pigs induced by different dietary amylose and amylopectin ratio. PloS one 20100101
Evolution of interferon-based therapy for chronic hepatitis C. Hepatitis research and treatment 20100101
Treatment of hepatitis C infections with interferon: a historical perspective. Hepatitis research and treatment 20100101
Severe Relapsing Goodpasture's Disease Successfully Treated with Mycophenolate Mofetil. International journal of nephrology 20100101
Recent advances in fragment-based QSAR and multi-dimensional QSAR methods. International journal of molecular sciences 20100101
Effect of different light intensities on total phenolics and flavonoids synthesis and anti-oxidant activities in young ginger varieties (Zingiber officinale Roscoe). International journal of molecular sciences 20100101
A comparative study of the inhibitory effects of purine nucleotides and carboxyatractylate on the uncoupling protein-3 and adenine nucleotide translocase. Acta biochimica Polonica 20100101
Alpha-Tocopherol Modulates Transcriptional Activities that Affect Essential Biological Processes in Bovine Cells. Gene regulation and systems biology 20100101
A genome alignment algorithm based on compression. BMC bioinformatics 20100101
A proposal for identifying the low renal uric acid clearance phenotype. Arthritis research & therapy 20100101
Physiological responses to folate overproduction in Lactobacillus plantarum WCFS1. Microbial cell factories 20100101
Study of nephrotoxic potential of acetaminophen in birds. Toxicology international 20100101
Plasma metabolomic profiles reflective of glucose homeostasis in non-diabetic and type 2 diabetic obese African-American women. PloS one 20100101
Direct injection of functional single-domain antibodies from E. coli into human cells. PloS one 20100101
Vaccination and infection prevention in inflammatory bowel disease. F1000 medicine reports 20100101
Distribution of short interstitial telomere motifs in two plant genomes: putative origin and function. BMC plant biology 20100101
Evidences showing wide presence of small genomic aberrations in chronic lymphocytic leukemia. BMC research notes 20100101
The colorectal cancer disease-specific transcriptome may facilitate the discovery of more biologically and clinically relevant information. BMC cancer 20100101
Serum neutrophil gelatinase-B associated lipocalin (NGAL) levels in Down's syndrome patients. Immunity & ageing : I & A 20100101
Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses. PloS one 20100101
Rituximab for the treatment of patients with chronic lymphocytic leukemia. Cancer management and research 20100101
Temsirolimus in the treatment of relapsed and/or refractory mantle cell lymphoma. Cancer management and research 20100101
Targeting the OB-Folds of Replication Protein A with Small Molecules. Journal of nucleic acids 20100101
Key Role of Human ABC Transporter ABCG2 in Photodynamic Therapy and Photodynamic Diagnosis. Advances in pharmacological sciences 20100101
An update in management of noncutaneous T-cell lymphomas. Advances in hematology 20100101
Rift Valley fever virus(Bunyaviridae: Phlebovirus): an update on pathogenesis, molecular epidemiology, vectors, diagnostics and prevention. Veterinary research 20100101
Transient expression of βC1 protein differentially regulates host genes related to stress response, chloroplast and mitochondrial functions. Virology journal 20100101
Complete Mitochondrial Genome Sequence of Acrida cinerea (Acrididae: Orthoptera) and Comparative Analysis of Mitochondrial Genomes in Orthoptera. Comparative and functional genomics 20100101
Analysis of KRAS Mutations of Exon 2 Codons 12 and 13 by SNaPshot Analysis in Comparison to Common DNA Sequencing. Gastroenterology research and practice 20100101
Epidemiology of gout. Arthritis research & therapy 20100101
Molecular mechanisms of ultraviolet radiation-induced DNA damage and repair. Journal of nucleic acids 20100101
CoFactor: Folate Requirement for Optimization of 5-Fluouracil Activity in Anticancer Chemotherapy. Journal of oncology 20100101
The biological and metabolic fates of endogenous DNA damage products. Journal of nucleic acids 20100101
Oral methylthioadenosine administration attenuates fibrosis and chronic liver disease progression in Mdr2-/- mice. PloS one 20100101
Phosphatidylserine increases IKBKAP levels in familial dysautonomia cells. PloS one 20100101
Formation and repair of tobacco carcinogen-derived bulky DNA adducts. Journal of nucleic acids 20100101
Disease modifying agents for multiple sclerosis. The open neurology journal 20100101
Glycolipid-Dependent, Protease Sensitive Internalization of Pseudomonas aeruginosa Into Cultured Human Respiratory Epithelial Cells. The open microbiology journal 20100101
The spectrum of use of rituximab in chronic lymphocytic leukemia. OncoTargets and therapy 20100101
Cancer chemotherapy: targeting folic acid synthesis. Cancer management and research 20100101
Clinical and experimental advances in regeneration of spinal cord injury. Journal of tissue engineering 20100101
Structure modeling of novel DNA glycosylase enzyme from oral pathogen Streptococcus sanguinis. Bioinformation 20100101
Mapping of origin of replication in Themococcales. Bioinformation 20100101
Epidemiology of pediatric urolithiasis. Indian journal of urology : IJU : journal of the Urological Society of India 20100101
Nutritional aspect of nephrolithiasis. Indian journal of urology : IJU : journal of the Urological Society of India 20100101
[Purine analgesia: experimental results and clinical perspectives]. Anesteziologiia i reanimatologiia 20100101
Application of new drugs in chronic lymphocytic leukemia. Mediterranean journal of hematology and infectious diseases 20100101
Allogeneic hematopoietic cell transplantation in the treatment of chronic lymphocytic leukemia: why and when? Mediterranean journal of hematology and infectious diseases 20100101
New treatments for myelodysplastic syndromes. Mediterranean journal of hematology and infectious diseases 20100101
Allogeneic transplantation for chronic lymphocytic leukemia. Mediterranean journal of hematology and infectious diseases 20100101
Biochemistry and occurrence of o-demethylation in plant metabolism. Frontiers in physiology 20100101
Ammonia production, excretion, toxicity, and defense in fish: a review. Frontiers in physiology 20100101
Update on the management of chronic eczema: new approaches and emerging treatment options. Clinical, cosmetic and investigational dermatology 20100101
[Plant purine nucleotide cyclases]. Postepy biochemii 20100101
History, epidemiology and regional diversities of urolithiasis. Pediatric nephrology (Berlin, Germany) 20100101
Genetic manipulation of francisella tularensis. Frontiers in microbiology 20100101
Genotoxicity and mutagenicity of Echinodorus macrophyllus (chapéu-de-couro) extracts. Genetics and molecular biology 20100101
Exploitation of host cell biology and evasion of immunity by francisella tularensis. Frontiers in microbiology 20100101
The Role of the Francisella Tularensis Pathogenicity Island in Type VI Secretion, Intracellular Survival, and Modulation of Host Cell Signaling. Frontiers in microbiology 20100101
Francisella tularensis metabolism and its relation to virulence. Frontiers in microbiology 20100101
Use of a rabbit soft tissue chamber model to investigate campylobacter jejuni-host interactions. Frontiers in microbiology 20100101
The francisella tularensis proteome and its recognition by antibodies. Frontiers in microbiology 20100101
The francisella intracellular life cycle: toward molecular mechanisms of intracellular survival and proliferation. Frontiers in microbiology 20100101
Advances in the management of gout: critical appraisal of febuxostat in the control of hyperuricemia. International journal of nephrology and renovascular disease 20100101
Role of tacrolimus combination therapy with mycophenolate mofetil in the prevention of organ rejection in kidney transplant patients. International journal of nephrology and renovascular disease 20100101
New and improved strategies for the treatment of gout. International journal of nephrology and renovascular disease 20100101
Chemical warfare agents. Journal of pharmacy & bioallied sciences 20100101
Radiation-induced biomarkers for the detection and assessment of absorbed radiation doses. Journal of pharmacy & bioallied sciences 20100101
Bladder dysfunction in diabetes mellitus. Frontiers in pharmacology 20100101
Cost effectiveness and quality of life considerations in the treatment of hepatitis C infection. ClinicoEconomics and outcomes research : CEOR 20100101
Cladribine and Fludarabine Nucleoside Change the Levels of CD Antigens on B-Lymphoproliferative Disorders. International journal of proteomics 20100101
Emerging therapies for treatment of multiple sclerosis. Journal of inflammation research 20100101
Management of Pneumocystis Jirovecii pneumonia in HIV infected patients: current options, challenges and future directions. HIV/AIDS (Auckland, N.Z.) 20100101
Critical analysis of herbs acting on Mutravaha srotas. Ayu 20100101
A clinical comparative study of the management of chronic renal failure with Punarnavadi compound. Ayu 20100101
Various techniques for the evaluation of anti arthritic activity in animal models. Journal of advanced pharmaceutical technology & research 20100101
Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL). Journal of blood medicine 20100101
Antiplatelet therapy in acute coronary syndromes: focus on ticagrelor. Journal of blood medicine 20100101
Adverse drug effects in hospitalized elderly: data from the healthcare cost and utilization project. Clinical pharmacology : advances and applications 20100101
Prevention and management of antineoplastic therapy induced oral mucositis. National journal of maxillofacial surgery 20100101
New Test System for Serine/Threonine Protein Kinase Inhibitors Screening: E. coli APHVIII/Pk25 design. Acta naturae 20100101
Discovery of an inhibitor of insulin-like growth factor 1 receptor activation: implications for cellular potency and selectivity over insulin receptor. Biochemical pharmacology 20091215
Functional characterization of intracellular Dictyostelium discoideum P2X receptors. The Journal of biological chemistry 20091211
Frameshift deletion by Sulfolobus solfataricus P2 DNA polymerase Dpo4 T239W is selective for purines and involves normal conformational change followed by slow phosphodiester bond formation. The Journal of biological chemistry 20091211
The structural basis for mRNA recognition and cleavage by the ribosome-dependent endonuclease RelE. Cell 20091211
Phase II study of flavopiridol in relapsed chronic lymphocytic leukemia demonstrating high response rates in genetically high-risk disease. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091210
Nucleobase lesions and strand breaks in dry DNA thin film selectively induced by monochromatic soft X-rays. The journal of physical chemistry. B 20091210
Synthesis of chiral 1,4-disubstituted-1,2,3-triazole derivatives from amino acids. Molecules (Basel, Switzerland) 20091209
Kinetic mechanism for the flipping and excision of 1,N(6)-ethenoadenine by human alkyladenine DNA glycosylase. Biochemistry 20091208
NMR investigation of DNA primer-template models: guanine templates are less prone to strand slippage upon misincorporation. Biochemistry 20091208
Reactions of Pd(II) with chelate-tethered 2,6-diaminopurine derivatives: N3-coordination and reaction of the purine system. Inorganic chemistry 20091207
Solution structure of RCL, a novel 2'-deoxyribonucleoside 5'-monophosphate N-glycosidase. Journal of molecular biology 20091204
Structural characterization of the mammalian deoxynucleotide N-hydrolase Rcl and its stabilizing interactions with two inhibitors. Journal of molecular biology 20091204
Effects of isovalerate on ruminal fermentation, urinary excretion of purine derivatives and digestibility in steers. Journal of animal physiology and animal nutrition 20091201
Influence of naturally-occurring 5'-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: an X-ray crystallographic study. Biopolymers 20091201
Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2. Biochimica et biophysica acta 20091201
Operons. Cellular and molecular life sciences : CMLS 20091201
Molecular evolution of GYPC: evidence for recent structural innovation and positive selection in humans. Molecular biology and evolution 20091201
Quantitative assessment of DNA replication to monitor microgametogenesis in Plasmodium berghei. Molecular and biochemical parasitology 20091201
Opioid use affects antioxidant activity and purine metabolism: preliminary results. Human psychopharmacology 20091201
Impaired up-regulation of polo-like kinase 2 in B-cell chronic lymphocytic leukaemia lymphocytes resistant to fludarabine and 2-chlorodeoxyadenosine: a potential marker of defective damage response. British journal of haematology 20091201
New insights into the pathogenesis of adenosine deaminase-severe combined immunodeficiency and progress in gene therapy. Current opinion in allergy and clinical immunology 20091201
Cystinuria: the South Indian experience. Urological research 20091201
Identification of survival genes in human glioblastoma cells by small interfering RNA screening. Molecular pharmacology 20091201
Dynamics of energy charge and adenine nucleotides during uncoupling of catabolism and anabolism in Penicillium ochrochloron. Mycological research 20091201
Nanoparticles can cause DNA damage across a cellular barrier. Nature nanotechnology 20091201
Pharmacokinetic role of protein binding of mycophenolic acid and its glucuronide metabolite in renal transplant recipients. Journal of pharmacokinetics and pharmacodynamics 20091201
In vivo assessment of mitochondrial toxicity of metacavir in Rhesus monkeys after three months of intravenous administration. Acta pharmacologica Sinica 20091201
Pathological features of bone marrow transplantation-related toxicity in a mouse. Journal of veterinary science 20091201
Graft-versus-leukemia effect of nonmyeloablative stem cell transplantation. The Korean journal of internal medicine 20091201
A purine scaffold Hsp90 inhibitor destabilizes BCL-6 and has specific antitumor activity in BCL-6-dependent B cell lymphomas. Nature medicine 20091201
Cladribine inhibits a diltiazem-induced increase in red blood cell purine nucleotide concentrations in a zebrafish model. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20091201
A mouse model of the human Fragile X syndrome I304N mutation. PLoS genetics 20091201
Transcriptome and proteome exploration to model translation efficiency and protein stability in Lactococcus lactis. PLoS computational biology 20091201
Preliminary crystallographic studies of purine nucleoside phosphorylase from the cariogenic pathogen Streptococcus mutans. Acta crystallographica. Section F, Structural biology and crystallization communications 20091201
Partition coefficients of some purine derivatives and its application to pharmacokinetics. Die Pharmazie 20091201
Terpenyl-purines from the sea. Marine drugs 20091201
Gouty tophi caused limited knee range of motion: a case report. Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20091201
Role of Cordycepin and Adenosine on the Phenotypic Switch of Macrophages via Induced Anti-inflammatory Cytokines. Immune network 20091201
Adult celiac disease and its malignant complications. Gut and liver 20091201
Catabolism of hyaluronan: involvement of transition metals. Interdisciplinary toxicology 20091201
6-Benzyl-sulfanyl-9H-purine. Acta crystallographica. Section E, Structure reports online 20091201
6-(4-Fluoro-pheneth-yl)-7-imino-3-phenyl-2,3,6,7-tetra-hydro-1,3-thia-zolo[4,5-d]pyrimidine-2-thione. Acta crystallographica. Section E, Structure reports online 20091201
Revisiting plus-strand DNA synthesis in retroviruses and long terminal repeat retrotransposons: dynamics of enzyme: substrate interactions. Viruses 20091201
Determination of the biological activity and structure activity relationships of drugs based on the highly cytotoxic duocarmycins and CC-1065. Toxins 20091201
Skew in the human caveolin 1 gene upstream purine complex homozygote haplotype compartment in multiple sclerosis. Journal of neuroimmunology 20091130
Cooperation between a coenzyme A-independent stand-alone initiation module and an iterative type I polyketide synthase during synthesis of mycobacterial phenolic glycolipids. Journal of the American Chemical Society 20091125
The GTPase activity of Escherichia coli FtsZ determines the magnitude of the FtsZ polymer bundling by ZapA in vitro. Biochemistry 20091124
Photophysics of xanthine: computational study of the radiationless decay mechanisms. Physical chemistry chemical physics : PCCP 20091121
Design and antimicrobial action of purine analogues that bind Guanine riboswitches. ACS chemical biology 20091120
Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. Biochemistry 20091117
Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice. British journal of cancer 20091117
Diagnosing and treating chronic lymphocytic leukemia in 2009. Oncology (Williston Park, N.Y.) 20091115
Uncoupling protein 1 inhibition by purine nucleotides is under the control of the endogenous ubiquinone redox state. The Biochemical journal 20091111
Structural perturbations induced by the alpha-anomer of the aflatoxin B(1) formamidopyrimidine adduct in duplex and single-strand DNA. Journal of the American Chemical Society 20091111
Structure-specific recognition of Friedreich's ataxia (GAA)n repeats by benzoquinoquinoxaline derivatives. Chembiochem : a European journal of chemical biology 20091102
Probing metal-ion purine interactions at DNA minor-groove sites. Inorganic chemistry 20091102
Medical treatment of pediatric urolithiasis. Pediatric nephrology (Berlin, Germany) 20091101
A 57-gene expression signature in B-cell chronic lymphocytic leukemia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20091101
Abnormal adenosine and dopamine receptor expression in lymphocytes of Lesch-Nyhan patients. Brain, behavior, and immunity 20091101
Identification of antigenic proteins associated with trichloroethylene-induced autoimmune disease by serological proteome analysis. Toxicology and applied pharmacology 20091101
Hypermetabolism, hyperphagia, and reduced adiposity in tankyrase-deficient mice. Diabetes 20091101
Polymorphisms in arsenic metabolism genes, urinary arsenic methylation profile and cancer. Cancer causes & control : CCC 20091101
A novel mutation in purine nucleoside phosphorylase in a child with normal uric acid levels. Clinical biochemistry 20091101
Simultaneous quantification of 9-(beta-D-1,3-dioxolan-4-yl)guanine, Amdoxovir and Zidovudine in human plasma by liquid chromatography-tandem mass spectrometric assay. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101
Proteome analysis of Lactobacillus rhamnosus GG using 2-D DIGE and mass spectrometry shows differential protein production in laboratory and industrial-type growth media. Journal of proteome research 20091101
Purine nucleotides reduce superoxide production by nitric oxide synthase in a murine sepsis model. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091101
NMR spectroscopy and kinetic studies of the quadruplex forming RNA r(UGGAGGU). Molecular bioSystems 20091101
Polymorphisms in one-carbon metabolism pathway genes and risk for bladder cancer in a Tunisian population. Cancer genetics and cytogenetics 20091101
Metabolomics applied to diabetes research: moving from information to knowledge. Diabetes 20091101
Adenosine A(3) receptor suppresses prostate cancer metastasis by inhibiting NADPH oxidase activity. Neoplasia (New York, N.Y.) 20091101
Plasmodium falciparum: new molecular targets with potential for antimalarial drug development. Expert review of anti-infective therapy 20091101
The malate synthase of Paracoccidioides brasiliensis Pb01 is required in the glyoxylate cycle and in the allantoin degradation pathway. Medical mycology 20091101
The germ cell nuclear proteins hnRNP G-T and RBMY activate a testis-specific exon. PLoS genetics 20091101
Sources of extracellular, oxidatively-modified DNA lesions: implications for their measurement in urine. Journal of clinical biochemistry and nutrition 20091101
Orange juice and hesperetin supplementation to hyperuricemic rats alter oxidative stress markers and xanthine oxidoreductase activity. Journal of clinical biochemistry and nutrition 20091101
Modifiers of Prat, a de novo purine synthesis gene, in Drosophila melanogaster. Genome 20091101
Review: what causes neurotoxicity after exposure to purine analogs? Clinical advances in hematology & oncology : H&O 20091101
Stereoselective synthesis of 2-deoxy-2-fluoroarabinofuranosyl-alpha-1-phosphate and its application to the synthesis of 2'-deoxy-2'-fluoroarabinofuranosyl purine nucleosides by a chemo-enzymatic method. Nucleosides, nucleotides & nucleic acids 20091101
The second-generation anticancer drug Nedaplatin: a theoretical investigation on the hydrolysis mechanism. The journal of physical chemistry. B 20091029
Structural basis for the inhibition of Mycobacterium tuberculosis glutamine synthetase by novel ATP-competitive inhibitors. Journal of molecular biology 20091023
Characterisation of influenza A viruses with mutations in segment 5 packaging signals. Vaccine 20091023
How I treat ADA deficiency. Blood 20091022
Integration of retroviral vectors induces minor changes in the transcriptional activity of T cells from ADA-SCID patients treated with gene therapy. Blood 20091022
The cis-(5R,6S)-thymine glycol lesion occupies the wobble position when mismatched with deoxyguanosine in DNA. Biochemistry 20091020
Brain purine metabolism and xanthine dehydrogenase/oxidase conversion in hyperammonemia are under control of NMDA receptors and nitric oxide. Brain research 20091019
MAP kinase dependent cyclinE/cdk2 activity promotes DNA replication in early sea urchin embryos. Developmental biology 20091015
Comparison of enzyme immobilisation methods for potentiometric phosphate biosensors. Biosensors & bioelectronics 20091015
Genetics of human neural tube defects. Human molecular genetics 20091015
Recent insights into the pathogenesis of hyperuricaemia and gout. Human molecular genetics 20091015
Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers. Journal of the American Chemical Society 20091014
Structural and metabolic specificity of methylthiocoformycin for malarial adenosine deaminases. Biochemistry 20091013
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency. Blood 20091008
Analysis of the interaction of the nucleotide base with myosin and the effect on substrate efficacy. Biophysical journal 20091007
Methotrexate for maintenance of remission in Crohn's disease. The Cochrane database of systematic reviews 20091007
A transthyretin-related protein is functionally expressed in Herbaspirillum seropedicae. Biochemical and biophysical research communications 20091002
Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase. The Journal of biological chemistry 20091002
Comparison of bacterial pellets and microbial markers for the estimation of the microbial nitrogen and amino acids flows from single flow continuous culture fermenters fed diets containing two-stage olive cake. Journal of animal physiology and animal nutrition 20091001
Co-expression of recombinant nucleoside phosphorylase from Escherichia coli and its application. Applied biochemistry and biotechnology 20091001
Portal vein thrombosis in adult-onset Still's disease: a case report and literature review. Rheumatology international 20091001
Synthesis, antiviral activity, and stability of nucleoside analogs containing tricyclic bases. European journal of medicinal chemistry 20091001
Different molecular mechanisms causing 9p21 deletions in acute lymphoblastic leukemia of childhood. Human genetics 20091001
ITPase-deficient mice show growth retardation and die before weaning. Cell death and differentiation 20091001
Clinical and experimental evidence of sympathetic neural dysfunction during inflammatory bowel disease. Clinical and experimental pharmacology & physiology 20091001
An insight to the dynamics of conserved water molecular triad in IMPDH II (human): recognition of cofactor and substrate to catalytic Arg 322. Journal of biomolecular structure & dynamics 20091001
DiProGB: the dinucleotide properties genome browser. Bioinformatics (Oxford, England) 20091001
A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme. Molecular & cellular proteomics : MCP 20091001
Phenotypic consequences of purine nucleotide imbalance in Saccharomyces cerevisiae. Genetics 20091001
Alterations in tryptophan and purine metabolism in cocaine addiction: a metabolomic study. Psychopharmacology 20091001
Xanthine oxidoreductase depletion induces renal interstitial fibrosis through aberrant lipid and purine accumulation in renal tubules. Hypertension (Dallas, Tex. : 1979) 20091001
Evolutionary changes to transthyretin: structure and function of a transthyretin-like ancestral protein. The FEBS journal 20091001
Purine nucleoside phosphorylases from hyperthermophilic Archaea require a CXC motif for stability and folding. The FEBS journal 20091001
Valproic acid- and lithium-sensitivity in prs mutants of Saccharomyces cerevisiae. Biochemical Society transactions 20091001
Feeding value of glycerol as a replacement for corn grain in rations fed to lactating dairy cows. Journal of dairy science 20091001
Photocycloaddition of the T1 excited state of thioinosine to uridine and adenosine. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20091001
Brugia malayi gene expression in response to the targeting of the Wolbachia endosymbiont by tetracycline treatment. PLoS neglected tropical diseases 20091001
Historical aspects and milestones in the development of effective treatment for hairy cell leukemia. Leukemia & lymphoma 20091001
Cladribine in the treatment of hairy cell leukemia: initial and subsequent results. Leukemia & lymphoma 20091001
Combination therapies to improve the long-term outcome in hairy cell leukemia. Leukemia & lymphoma 20091001
Long-term follow-up studies in hairy cell leukemia. Leukemia & lymphoma 20091001
Approach to the patient after relapse of hairy cell leukemia. Leukemia & lymphoma 20091001
Structure-based predictive models for allosteric hot spots. PLoS computational biology 20091001
Recent progress in the treatment of acute lymphoblastic leukemia: clofarabine. Hematology/oncology clinics of North America 20091001
Modern concepts in the treatment of chronic lymphocytic leukemia. Hematology (Amsterdam, Netherlands) 20091001
Structure of Mycobacterium tuberculosis Rv2714, a representative of a duplicated gene family in Actinobacteria. Acta crystallographica. Section F, Structural biology and crystallization communications 20091001
1+1 = 3: a fusion of 2 enzymes in the methionine salvage pathway of Tetrahymena thermophila creates a trifunctional enzyme that catalyzes 3 steps in the pathway. PLoS genetics 20091001
Helminth genomics: The implications for human health. PLoS neglected tropical diseases 20091001
Infectious complications in patients with chronic lymphocytic leukemia: pathogenesis, spectrum of infection, and approaches to prophylaxis. Clinical lymphoma & myeloma 20091001
Light directs zebrafish period2 expression via conserved D and E boxes. PLoS biology 20091001
Progressive GAA.TTC repeat expansion in human cell lines. PLoS genetics 20091001
Malaria vaccines: where next? PLoS pathogens 20091001
Purine biosynthetic pathway genes and methotrexate response in rheumatoid arthritis patients among north Indians. Pharmacogenetics and genomics 20091001
[Using adaptive mutagenesis system for identification of early genes encoding de novo purine biosynthesis in methylotrophic yeast Pichia methanolica MH4]. Genetika 20091001
Urate urolithiasis. Compendium (Yardley, PA) 20091001
GeneWiz browser: An Interactive Tool for Visualizing Sequenced Chromosomes. Standards in genomic sciences 20090929
Functional study of the P32T ITPA variant associated with drug sensitivity in humans. Journal of molecular biology 20090925
Targeting glucose consumption and autophagy in myeloma with the novel nucleoside analogue 8-aminoadenosine. The Journal of biological chemistry 20090925
Punching holes in an enzyme. Chemistry & biology 20090925
Ribocation transition state capture and rebound in human purine nucleoside phosphorylase. Chemistry & biology 20090925
Steric and electrostatic effects at the C2 atom substituent influence replication and miscoding of the DNA deamination product deoxyxanthosine and analogs by DNA polymerases. Journal of molecular biology 20090918
Electrochemical detection of natural DNA damage induced by ferritin/ascorbic acid/H2O2 system and amplification of DNA damage by endonuclease Fpg. Biosensors & bioelectronics 20090915
Polar anionic metabolome analysis by nano-LC/MS with a metal chelating agent. Analytical chemistry 20090915
Role of intramembrane polar residues in the YgfO xanthine permease: HIS-31 and ASN-93 are crucial for affinity and specificity, and ASP-304 and GLU-272 are irreplaceable. The Journal of biological chemistry 20090904
The genomes of the South American opossum (Monodelphis domestica) and platypus (Ornithorhynchus anatinus) encode a more complete purine catabolic pathway than placental mammals. Comparative biochemistry and physiology. Part D, Genomics & proteomics 20090903
Polarizable empirical force field for nitrogen-containing heteroaromatic compounds based on the classical Drude oscillator. Journal of computational chemistry 20090901
The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury. Shock (Augusta, Ga.) 20090901
Glutathione-supported arsenate reduction coupled to arsenolysis catalyzed by ornithine carbamoyl transferase. Toxicology and applied pharmacology 20090901
Synthesis of a series of N6-substituted adenosines with activity against trypanosomatid parasites. European journal of medicinal chemistry 20090901
Risk factors for severe infection in patients with hairy cell leukemia: a long-term study of 73 patients. European journal of haematology 20090901
DNA interactions and photocatalytic strand cleavage by artificial nucleases based on water-soluble gold(III) porphyrins. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090901
Encapsulation of ruthenium nitrosylnitrate and DNA purines in nanostructured sol-gel silica matrices. Langmuir : the ACS journal of surfaces and colloids 20090901
Time-course changes in ectonucleotidase activities during experimental autoimmune encephalomyelitis. Neurochemistry international 20090901
The role of transporters in the pharmacokinetics of orally administered drugs. Pharmaceutical research 20090901
Interaction of human DNA polymerase alpha and DNA polymerase I from Bacillus stearothermophilus with hypoxanthine and 8-oxoguanine nucleotides. Biochemistry 20090901
The transcriptionally active regions in the genome of Bacillus subtilis. Molecular microbiology 20090901
Gout: is a purine-restricted diet still recommended? Journal of the American Dietetic Association 20090901
Effect of pH and level of concentrate in the diet on the production of biohydrogenation intermediates in a dual-flow continuous culture. Journal of dairy science 20090901
Acceleration of purine degradation by periodontal diseases. Journal of dental research 20090901
Exploration of uncharted regions of the protein universe. PLoS biology 20090901
Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal. PLoS neglected tropical diseases 20090901
Genomic diversity and evolution of Mycobacterium ulcerans revealed by next-generation sequencing. PLoS pathogens 20090901
Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives. Marine drugs 20090901
[Effects of heroin and purine nucleotide compensation on neutral alpha-glucosidase in rat epididymides]. Zhonghua nan ke xue = National journal of andrology 20090901
Adenosine-based modulation of brain activity. Current neuropharmacology 20090901
Release of adenosine and ATP during ischemia and epilepsy. Current neuropharmacology 20090901
Tuning and fine-tuning of synapses with adenosine. Current neuropharmacology 20090901
Adenosine A(2A) receptors in psychopharmacology: modulators of behavior, mood and cognition. Current neuropharmacology 20090901
The role of adenosine in Alzheimer's disease. Current neuropharmacology 20090901
Adenosine and stroke: maximizing the therapeutic potential of adenosine as a prophylactic and acute neuroprotectant. Current neuropharmacology 20090901
Adenosine and the auditory system. Current neuropharmacology 20090901
Adenosine, ketogenic diet and epilepsy: the emerging therapeutic relationship between metabolism and brain activity. Current neuropharmacology 20090901
Carcinoma and multiple lymphomas in one patient: establishing the diagnoses and analyzing risk factors. Journal of hematopathology 20090901
Viroid replication: rolling-circles, enzymes and ribozymes. Viruses 20090901
Guanine deaminase functions as dihydropterin deaminase in the biosynthesis of aurodrosopterin, a minor red eye pigment of Drosophila. The Journal of biological chemistry 20090828
Synthesis and conformational analysis of locked carbocyclic analogues of 1,3-diazepinone riboside, a high-affinity cytidine deaminase inhibitor. The Journal of organic chemistry 20090821
Pd(0)/Cu(I)-mediated direct arylation of 2'-deoxyadenosines: mechanistic role of Cu(I) and reactivity comparisons with related purine nucleosides. The Journal of organic chemistry 20090821
Forodesine has high antitumor activity in chronic lymphocytic leukemia and activates p53-independent mitochondrial apoptosis by induction of p73 and BIM. Blood 20090820
Templated synthesis of peptide nucleic acids via sequence-selective base-filling reactions. Journal of the American Chemical Society 20090819
Adenosine: an endogenous modulator of innate immune system with therapeutic potential. European journal of pharmacology 20090815
Identification of inhibitors of checkpoint kinase 1 through template screening. Journal of medicinal chemistry 20090813
Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Biochemistry 20090804
A study of pyrimidine base damage in relation to oxidative stress and cancer. British journal of cancer 20090804
Molecular modeling and dynamics studies of purine nucleoside phosphorylase from Bacteroides fragilis. Journal of molecular modeling 20090801
Mechanical and kinetic effects of shortened tropomyosin reconstituted into myofibrils. Pflugers Archiv : European journal of physiology 20090801
Substrate-dependent modulation of enzyme activity by allosteric effector antibodies. Biochimica et biophysica acta 20090801
Cross-linking to an interrupted polypurine sequence with a platinum-modified triplex-forming oligonucleotide. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090801
Determination of purine contents of alcoholic beverages using high performance liquid chromatography. Biomedical chromatography : BMC 20090801
Hypoxanthine-guanine phosphoribosyltransferase from Mycobacterium tuberculosis H37Rv: cloning, expression, and biochemical characterization. Protein expression and purification 20090801
Theoretical studies on the interaction of modified pyrimidines and purines with purine riboswitch. Journal of molecular graphics & modelling 20090801
Allantoin in human plasma, serum, and nasal-lining fluids as a biomarker of oxidative stress: avoiding artifacts and establishing real in vivo concentrations. Antioxidants & redox signaling 20090801
Inhibition of de novo purine synthesis in human prostate cells results in ATP depletion, AMPK activation and induces senescence. The Prostate 20090801
Up-regulation of the inflammatory-reparative phenotype in human prostate carcinoma. The Prostate 20090801
The enzymes of the 10-formyl-tetrahydrofolate synthetic pathway are found exclusively in the cytosol of the trypanosomatid parasite Leishmania major. Molecular and biochemical parasitology 20090801
Effects of the purL gene expression level on the competitive nodulation ability of Sinorhizobium fredii. Current microbiology 20090801
Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801
Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: I. The role of arsenolysis. Toxicological sciences : an official journal of the Society of Toxicology 20090801
Mechanism of thiol-supported arsenate reduction mediated by phosphorolytic-arsenolytic enzymes: II. Enzymatic formation of arsenylated products susceptible for reduction to arsenite by thiols. Toxicological sciences : an official journal of the Society of Toxicology 20090801
The effect of endurance training on changes in purine metabolism: a longitudinal study of competitive long-distance runners. European journal of applied physiology 20090801
Synthesis of 9-beta-d-arabinofuranosylguanine by combined use of two whole cell biocatalysts. Bioorganic & medicinal chemistry letters 20090801
Cooperative regulation of ADE3 transcription by Gcn4p and Bas1p in Saccharomyces cerevisiae. Eukaryotic cell 20090801
Oxygen and guanine-cytosine profiles in marine environments. Journal of molecular evolution 20090801
Regulation of osteogenesis-angiogenesis coupling by HIFs and VEGF. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090801
Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part I. Bioorganic & medicinal chemistry letters 20090801
Role of ATP and related purines in inhibitory neurotransmission to the pig urinary bladder neck. British journal of pharmacology 20090801
Azathioprine and 6-mercaptopurine for the prevention of postoperative recurrence in Crohn's disease: a meta-analysis. The American journal of gastroenterology 20090801
Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development. Development (Cambridge, England) 20090801
Synthetic strategies toward carbocyclic purine-pyrimidine hybrid nucleosides. Bioorganic & medicinal chemistry 20090801
Cladribine: not just another purine analogue? Expert opinion on investigational drugs 20090801
Na-butyrate sustains energetic states of metabolism and t-PA productivity of CHO cells. Journal of bioscience and bioengineering 20090801
Point: steady progress and current challenges in clinical islet transplantation. Diabetes care 20090801
Preclinical assessment of the treatment of second-stage African trypanosomiasis with cordycepin and deoxycoformycin. PLoS neglected tropical diseases 20090801
Tissue effect on genetic control of transcript isoform variation. PLoS genetics 20090801
[Separation of the up-regulated genes under nitrogen starvation from Phaeodactylum tricornutum by suppression subtractive hybridization technology]. Yi chuan = Hereditas 20090801
Adenosine Kinase of T. b. Rhodesiense identified as the putative target of 4-[5-(4-phenoxyphenyl)-2H-pyrazol-3-yl]morpholine using chemical proteomics. PLoS neglected tropical diseases 20090801
Syzygium cumini inhibits adenosine deaminase activity and reduces glucose levels in hyperglycemic patients. Fundamental & clinical pharmacology 20090801
Roscovitine triggers apoptosis in B-cell chronic lymphocytic leukemia cells with similar efficiency as combinations of conventional purine analogs with cyclophosphamide. Annals of the New York Academy of Sciences 20090801
Selective cyclin-dependent kinase inhibitors discriminating between cell cycle and transcriptional kinases: future reality or utopia? Annals of the New York Academy of Sciences 20090801
Is olomoucine, a weak CDK2 inhibitor, able to induce apoptosis in cancer cells? Annals of the New York Academy of Sciences 20090801
ATP as modulator of carbacholine effect on contractility of rat myocardium in postnatal ontogeny. Bulletin of experimental biology and medicine 20090801
A focus on natural variation for abiotic constraints response in the model species Arabidopsis thaliana. International journal of molecular sciences 20090801
Chemical diversity and defence metabolism: how plants cope with pathogens and ozone pollution. International journal of molecular sciences 20090801
Myocardial energetics in left ventricular hypertrophy. Current cardiology reviews 20090801
4-Hydrazino-1-methyl-pyrazolo[3,4-d]pyrimidine. Acta crystallographica. Section E, Structure reports online 20090801
Abacavir methanol 2.5-solvate. Acta crystallographica. Section E, Structure reports online 20090801
Mechanism for attenuation of DNA binding by MarR family transcriptional regulators by small molecule ligands. Journal of molecular biology 20090731
De novo deletion 17p13.1 chronic lymphocytic leukemia shows significant clinical heterogeneity: the M. D. Anderson and Mayo Clinic experience. Blood 20090730
Plexin B1 is repressed by oncogenic B-Raf signaling and functions as a tumor suppressor in melanoma cells. Oncogene 20090730
Escherichia coli DnaB helicase-DnaC protein complex: allosteric effects of the nucleotides on the nucleic acid binding and the kinetic mechanism of NTP hydrolysis. 3. Biochemistry 20090728
Mechanism of NTP hydrolysis by the Escherichia coli primary replicative helicase DnaB protein. 2. Nucleotide and nucleic acid specificities. Biochemistry 20090728
Probing anomalous structural features in polypurine tract-containing RNA-DNA hybrids with neomycin B. Biochemistry 20090728
Inhibition of hypoxanthine-guanine phosphoribosyltransferase by acyclic nucleoside phosphonates: a new class of antimalarial therapeutics. Journal of medicinal chemistry 20090723
Dynamics of macrophage polarization reveal new mechanism to inhibit IL-1beta release through pyrophosphates. The EMBO journal 20090722
Efficient charge transport in DNA diblock oligomers. Journal of the American Chemical Society 20090722
A simple method for C-6 modification of guanine nucleosides. Organic & biomolecular chemistry 20090721
MLH1 expression sensitises ovarian cancer cells to cell death mediated by XIAP inhibition. British journal of cancer 20090721
Synthesis of novel purine nucleosides towards a selective inhibition of human butyrylcholinesterase. Bioorganic & medicinal chemistry 20090715
PcrA helicase tightly couples ATP hydrolysis to unwinding double-stranded DNA, modulated by the initiator protein for plasmid replication, RepD. Biochemistry 20090714
Antithetical effects of corticosterone and dibutyryl cAMP on adenosine deaminase in the gastrointestinal tract of chicken during postnatal development. Molecular and cellular biochemistry 20090701
New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC. Inflammatory bowel diseases 20090701
Purification, properties, and kinetic studies of cytoplasmic malate dehydrogenase from Taenia solium cysticerci. Parasitology research 20090701
A comparative study on urinary purine derivative excretion of yak (Bos grunniens), cattle (Bos taurus), and crossbred (Bos taurus x Bos grunniens) in the Qinghai-Tibetan plateau, China. Journal of animal science 20090701
Diet, fluid, or supplements for secondary prevention of nephrolithiasis: a systematic review and meta-analysis of randomized trials. European urology 20090701
Increase of uric acid and purine compounds in biological fluids of multiple sclerosis patients. Clinical biochemistry 20090701
Development of gene therapy in association with clinically used cytotoxic deoxynucleoside analogues. Cancer gene therapy 20090701
Novel therapies for peripheral T-cell non-Hodgkin's lymphomas. Current opinion in hematology 20090701
Treatment of fludarabine-refractory chronic lymphocytic leukemia. Cancer 20090701
A functional analysis of the pyrimidine catabolic pathway in Arabidopsis. The New phytologist 20090701
Immunosuppression in inflammatory bowel disease: traditional, biological or both? Current opinion in gastroenterology 20090701
Catalytically impaired hMYH and NEIL1 mutant proteins identified in patients with primary sclerosing cholangitis and cholangiocarcinoma. Carcinogenesis 20090701
Local and systemic oxidant/antioxidant status before and during lung cancer radiotherapy. Free radical research 20090701
Antimalarial activity of thiosemicarbazones and purine derived nitriles. Bioorganic & medicinal chemistry letters 20090701
Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer. Chemical reviews 20090701
Regio- and enantioselective N-allylations of imidazole, benzimidazole, and purine heterocycles catalyzed by single-component metallacyclic iridium complexes. Journal of the American Chemical Society 20090701
Characterization of the major formamidopyrimidine-DNA glycosylase homolog in Mycobacterium tuberculosis and its linkage to variable tandem repeats. FEMS immunology and medical microbiology 20090701
Synthesis and anti-Hantaan virus activity of N(1)-3-fluorophenyl-inosine. Antiviral research 20090701
Adenosine A(2A) receptor mediates microglial process retraction. Nature neuroscience 20090701
Bendamustine therapy in chronic lymphocytic leukemia. Expert opinion on pharmacotherapy 20090701
Impact of ketone and amino on the inner shell of guanine. Journal of synchrotron radiation 20090701
Hairy-cell leukemia with inaugural joint manifestations. Joint, bone, spine : revue du rhumatisme 20090701
Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition. Cancer research 20090701
The effects of arbuscular mycorrhizal fungi on direct and indirect defense metabolites of Plantago lanceolata L. Journal of chemical ecology 20090701
Functional and structural alterations induced by copper in xanthine oxidase. Acta biochimica et biophysica Sinica 20090701
Radiation metabolomics. 2. Dose- and time-dependent urinary excretion of deaminated purines and pyrimidines after sublethal gamma-radiation exposure in mice. Radiation research 20090701
Comparative expression profiling of Leishmania: modulation in gene expression between species and in different host genetic backgrounds. PLoS neglected tropical diseases 20090701
Changes in plasma concentrations of hypoxanthine and uric acid before and after hemodialysis. Iranian journal of kidney diseases 20090701
Cooperativity dominates the genomic organization of p53-response elements: a mechanistic view. PLoS computational biology 20090701
Comprehensive identification of Salmonella enterica serovar typhimurium genes required for infection of BALB/c mice. PLoS pathogens 20090701
[Hairy cell leukemia: Part II: therapy with cladribine]. Medizinische Monatsschrift fur Pharmazeuten 20090701
4-(1-Adamantylmeth-yl)-N-(2-chloro-9-isopropyl-9H-purin-6-yl)aniline. Acta crystallographica. Section E, Structure reports online 20090701
New approaches for cancer treatment: antitumor drugs based on gene-targeted nucleic acids. Acta naturae 20090701
Spinal mechanisms of antinociceptive action caused by guanosine in mice. European journal of pharmacology 20090624
Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb. The Journal of neuroscience : the official journal of the Society for Neuroscience 20090624
Substituted cysteine accessibility method analysis of human concentrative nucleoside transporter hCNT3 reveals a novel discontinuous region of functional importance within the CNT family motif (G/A)XKX3NEFVA(Y/M/F). The Journal of biological chemistry 20090619
Conserved glutamate residues Glu-343 and Glu-519 provide mechanistic insights into cation/nucleoside cotransport by human concentrative nucleoside transporter hCNT3. The Journal of biological chemistry 20090619
Biochemical and biophysical analysis of five disease-associated human adenylosuccinate lyase mutants. Biochemistry 20090616
Altered enthalpy-entropy compensation in picomolar transition state analogues of human purine nucleoside phosphorylase. Biochemistry 20090616
Substrate specificity and kinetic mechanism of purine nucleoside phosphorylase from Mycobacterium tuberculosis. Archives of biochemistry and biophysics 20090615
Identifying novel constrained elements by exploiting biased substitution patterns. Bioinformatics (Oxford, England) 20090615
Metabolic intermediates selectively stimulate transcription factor interaction and modulate phosphate and purine pathways. Genes & development 20090615
Molecular adaptation in RNA complexes. Structure (London, England : 1993) 20090610
Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylase. The Journal of biological chemistry 20090605
Kinetic analysis of base-pairing preference for nucleotide incorporation opposite template pyrimidines by human DNA polymerase iota. Journal of molecular biology 20090605
Discrimination between right and wrong purine dNTPs by DNA polymerase I from Bacillus stearothermophilus. Biochemistry 20090602
Multiple endonucleases improve MALDI-MS signature digestion product detection of bacterial transfer RNAs. Analytical and bioanalytical chemistry 20090601
Modeling the noncovalent interactions at the metabolite binding site in purine riboswitches. Journal of molecular modeling 20090601
The P2X(7) receptor-pannexin connection to dye uptake and IL-1beta release. Purinergic signalling 20090601
Vinasse added to dried sugar beet pulp: preference rate, voluntary intake, and digestive utilization in sheep. Journal of animal science 20090601
P2 purinergic receptor mRNA in rat and human sinoatrial node and other heart regions. Naunyn-Schmiedeberg's archives of pharmacology 20090601
The effect of ultraviolet radiation on the accumulation of medicinal compounds in plants. Fitoterapia 20090601
Crystal structures of T. vivax nucleoside hydrolase in complex with new potent and specific inhibitors. Biochimica et biophysica acta 20090601
Molecular modeling, dynamics and docking studies of purine nucleoside phosphorylase from Streptococcus pyogenes. Biophysical chemistry 20090601
Transepithelial fluxes of adenosine and 2'-deoxyadenosine across human renal proximal tubule cells: roles of nucleoside transporters hENT1, hENT2, and hCNT3. American journal of physiology. Renal physiology 20090601
Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis. American journal of physiology. Lung cellular and molecular physiology 20090601
Efficacy of mizoribine pulse therapy in patients with rheumatoid arthritis who show a reduced or insufficient response to infliximab. Modern rheumatology 20090601
FYX-051, a xanthine oxidoreductase inhibitor, induces nephropathy in rats, but not in monkeys. Toxicologic pathology 20090601
Long-term follow-up of 233 patients with hairy cell leukaemia, treated initially with pentostatin or cladribine, at a median of 16 years from diagnosis. British journal of haematology 20090601
Podocyte-specific expression of organic cation transporter PMAT: implication in puromycin aminonucleoside nephrotoxicity. American journal of physiology. Renal physiology 20090601
Effect of dietary purines on the pharmacokinetics of orally administered ribavirin. Journal of clinical pharmacology 20090601
From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later. Microbiology (Reading, England) 20090601
Simultaneous electrochemical monitoring of metabolites related to the xanthine oxidase pathway using a grinded carbon electrode. Analytical chemistry 20090601
Purine uptake in Plasmodium: transport versus metabolism. Trends in parasitology 20090601
Borrelia burgdorferi bb0426 encodes a 2'-deoxyribosyltransferase that plays a central role in purine salvage. Molecular microbiology 20090601
Induction of neurogenesis in rat bone marrow mesenchymal stem cells using purine structure-based compounds. Molecular bioSystems 20090601
Clofarabine: a new treatment option for patients with acute myeloid leukemia. Expert opinion on pharmacotherapy 20090601
[Prevalence and composition of urolithiasis in a pediatric Tunisian population]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20090601
Improvement of purine and pyrimidine antimetabolite-based anticancer treatment by selective suppression of mycoplasma-encoded catabolic enzymes. The Lancet. Oncology 20090601
Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations. PLoS genetics 20090601
Genomic analyses of the microsporidian Nosema ceranae, an emergent pathogen of honey bees. PLoS pathogens 20090601
FINDSITE: a threading-based approach to ligand homology modeling. PLoS computational biology 20090601
Clofarabine as a novel nucleoside analogue approved to treat patients with haematological malignancies: mechanism of action and clinical activity. Mini reviews in medicinal chemistry 20090601
Ribavirin acts via multiple pathways in inhibition of leukemic cell proliferation. Anticancer research 20090601
Chronic lymphocytic leukemia: long-lasting remission with combination of cyclophosphamide, somatostatin, bromocriptine, retinoids, melatonin, and ACTH. Cancer biotherapy & radiopharmaceuticals 20090601
Chiral analysis of anti-acquired immunodeficiency syndrome drug, 9-(R)-[2-(phosphonomethoxy)propyl]adenine (tenofovir), and related antiviral acyclic nucleoside phosphonates by CE using beta-CD as chiral selector. Electrophoresis 20090601
Celebrating Achim Trebst's 80th birthday. Photosynthesis research 20090601
Precambrian lunar volcanic protolife. International journal of molecular sciences 20090601
Proteomic signature of reversine-treated murine fibroblasts by 2-D difference gel electrophoresis and MS: possible associations with cell signalling networks. Electrophoresis 20090601
Pentostatin treatment combinations in chronic lymphocytic leukemia. Clinical advances in hematology & oncology : H&O 20090601
Effect of fortifying concentrate supplement with fibrolytic enzymes on nutrient utilization, milk yield and composition in lactating goats. Animal science journal = Nihon chikusan Gakkaiho 20090601
Adenosine and adenosine receptors: Newer therapeutic perspective. Indian journal of pharmacology 20090601
Possibilities of alternative generation II biotests at Artemia. Interdisciplinary toxicology 20090601
(1-Adamant-yl){4-[(2-chloro-9-isopropyl-9H-purin-6-yl)aminometh-yl]phen-yl}methanone trichloro-methane solvate. Acta crystallographica. Section E, Structure reports online 20090601
The stimulatory effect of the organic sulfur supplement, mercaptopropane sulfonic acid on cellulolytic rumen microorganisms and microbial protein synthesis in cattle fed low sulfur roughages. Animal : an international journal of animal bioscience 20090601
Analysis of 7,8-dihydro-8-oxo-2'-deoxyguanosine in cellular DNA during oxidative stress. Chemical research in toxicology 20090518
Chemistry and biology of DNA containing 1,N(2)-deoxyguanosine adducts of the alpha,beta-unsaturated aldehydes acrolein, crotonaldehyde, and 4-hydroxynonenal. Chemical research in toxicology 20090518
Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part II. Bioorganic & medicinal chemistry letters 20090515
Synthesis of analogs of forodesine HCl, a human purine nucleoside phosphorylase inhibitor-Part I. Bioorganic & medicinal chemistry letters 20090515
Progressive multifocal leukoencephalopathy after rituximab therapy in HIV-negative patients: a report of 57 cases from the Research on Adverse Drug Events and Reports project. Blood 20090514
Fructose-1,6-bisphosphatase inhibitors. 1. Purine phosphonic acids as novel AMP mimics. Journal of medicinal chemistry 20090514
Synthesis and biological activity of a novel series of 6-substituted thieno[2,3-d]pyrimidine antifolate inhibitors of purine biosynthesis with selectivity for high affinity folate receptors over the reduced folate carrier and proton-coupled folate transporter for cellular entry. Journal of medicinal chemistry 20090514
Conserved cysteine residues of GidA are essential for biogenesis of 5-carboxymethylaminomethyluridine at tRNA anticodon. Structure (London, England : 1993) 20090513
Inhibition of erythrocyte phosphoribosyltransferases (APRT and HPRT) by Pb2+: a potential mechanism of lead toxicity. Toxicology 20090502
Inhibition of Na+ transport in lung epithelial cells by respiratory syncytial virus infection. American journal of respiratory cell and molecular biology 20090501
Reduced-intensity conditioning for severe aplasia using fludarabine and CY followed by infusion of ex vivo T-cell-depleted grafts leads to excellent engraftment and absence of GVHD. Bone marrow transplantation 20090501
Purinergic receptor activation evokes neurotrophic factor neuropeptide Y release from neonatal mouse olfactory epithelial slices. Journal of neuroscience research 20090501
Separation and identification of purine nucleosides in the urine of patients with malignant cancer by reverse phase liquid chromatography/electrospray tandem mass spectrometry. Journal of mass spectrometry : JMS 20090501
Damage recognition by UV damage endonuclease from Schizosaccharomyces pombe. DNA repair 20090501
Behavioral response of human spermatozoa to a concentration jump of chemoattractants or intracellular cyclic nucleotides. Human reproduction (Oxford, England) 20090501
The transport of anti-HIV drugs across blood-CNS interfaces: summary of current knowledge and recommendations for further research. Antiviral research 20090501
Ectonucleoside triphosphate diphosphohydrolase type 5 (Entpd5)-deficient mice develop progressive hepatopathy, hepatocellular tumors, and spermatogenic arrest. Veterinary pathology 20090501
Increased xanthine oxidase in the skin of preeclamptic women. Reproductive sciences (Thousand Oaks, Calif.) 20090501
Protection of midbrain dopaminergic neurons by the end-product of purine metabolism uric acid: potentiation by low-level depolarization. Journal of neurochemistry 20090501
Management of erectile function by penile purinergic p2 receptors in the diabetic rat. The Journal of urology 20090501
Purinergic signalling in autonomic control. Trends in neurosciences 20090501
Structure of a mutant human purine nucleoside phosphorylase with the prodrug, 2-fluoro-2'-deoxyadenosine and the cytotoxic drug, 2-fluoroadenine. Protein science : a publication of the Protein Society 20090501
Liver and inflammatory bowel disease. Gastroenterologie clinique et biologique 20090501
Autoimmune pancytopenia following combination chemotherapy for chronic lymphocytic leukaemia. Journal of clinical pathology 20090501
Methotrexate treatment in pediatric Crohn disease patients intolerant or resistant to purine analogues. Journal of pediatric gastroenterology and nutrition 20090501
Probing the functional impact of sequence variation on p53-DNA interactions using a novel microsphere assay for protein-DNA binding with human cell extracts. PLoS genetics 20090501
Widespread genomic signatures of natural selection in hominid evolution. PLoS genetics 20090501
Additions, losses, and rearrangements on the evolutionary route from a reconstructed ancestor to the modern Saccharomyces cerevisiae genome. PLoS genetics 20090501
[Malignant lymphomas]. Gan to kagaku ryoho. Cancer & chemotherapy 20090501
Plk1 self-organization and priming phosphorylation of HsCYK-4 at the spindle midzone regulate the onset of division in human cells. PLoS biology 20090501
Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies. PLoS pathogens 20090501
Allopurinol, an inhibitor of uric acid synthesis--can it be used for the treatment of metabolic syndrome and related disorders? Drugs of today (Barcelona, Spain : 1998) 20090501
Modulation of RNA metal binding by flanking bases: 15N NMR evaluation of GC, tandem GU, and tandem GA sites. Nucleosides, nucleotides & nucleic acids 20090501
Synthesis and antiviral evaluation of 4'-C-azidomethyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides. Nucleosides, nucleotides & nucleic acids 20090501
Synthesis and antiviral activity of purine 2',3'-dideoxy-2',3'-difluoro-D-arabinofuranosyl nucleosides. Nucleosides, nucleotides & nucleic acids 20090501
Synthesis and anticancer evaluation of 4'-C-methyl-2'-fluoro arabino nucleosides. Nucleosides, nucleotides & nucleic acids 20090501
International prognostic scoring system for Waldenstrom macroglobulinemia. Blood 20090430
Loop-tryptophan human purine nucleoside phosphorylase reveals submillisecond protein dynamics. Biochemistry 20090428
Essential role of one-carbon metabolism and Gcn4p and Bas1p transcriptional regulators during adaptation to anaerobic growth of Saccharomyces cerevisiae. The Journal of biological chemistry 20090424
Polypurine hairpins directed against the template strand of DNA knock down the expression of mammalian genes. The Journal of biological chemistry 20090424
Effect of N7-protonated purine nucleosides on formation of C8 adducts in carcinogenic reactions of arylnitrenium ions with purine nucleosides: a quantum chemistry study. The journal of physical chemistry. B 20090423
Identifying the features of purine dNTPs that allow accurate and efficient DNA replication by herpes simplex virus I DNA polymerase. Biochemistry 20090421
Methodological approaches in application of synthetic lethality screening towards anticancer therapy. British journal of cancer 20090421
Synthesis of nucleoside Di- and triphosphates and dinucleoside polyphosphates with cycloSal-nucleotides. The Journal of organic chemistry 20090417
Analysis of somatic hypermutation in X-linked hyper-IgM syndrome shows specific deficiencies in mutational targeting. Blood 20090416
A study of the ultrastructure of fragile-X-related proteins. The Biochemical journal 20090415
A new synthesis and an antiviral assessment of the 4'-fluoro derivative of 4'-deoxy-5'-noraristeromycin. Bioorganic & medicinal chemistry 20090415
The A2B adenosine receptor impairs the maturation and immunogenicity of dendritic cells. Journal of immunology (Baltimore, Md. : 1950) 20090415
Antimicrobial resistance induced by genetic changes. Journal of medicine and life 20090415
Contribution of the reverse rate of the conformational step to polymerase beta fidelity. Biochemistry 20090414
Biochemical characterization of the HpxO enzyme from Klebsiella pneumoniae, a novel FAD-dependent urate oxidase. Biochemistry 20090414
Efficient procedure for isolating methylated catechins from green tea and effective simultaneous analysis of ten catechins, three purine alkaloids, and gallic acid in tea by high-performance liquid chromatography with diode array detection. Journal of chromatography. A 20090410
Synthesis and anti-HIV activity of conformationally restricted bicyclic hexahydroisobenzofuran nucleoside analogs. Organic & biomolecular chemistry 20090407
Sulfinosine enhances doxorubicin efficacy through synergism and by reversing multidrug resistance in the human non-small cell lung carcinoma cell line (NCI-H460/R). Investigational new drugs 20090401
The effects of concentrate added to pineapple (Ananas comosus Linn. Mer.) waste silage in differing ratios to form complete diets, on digestion, excretion of urinary purine derivatives and blood metabolites in growing, male, Thai swamp buffaloes. Tropical animal health and production 20090401
Inhibition of human poly(A)-specific ribonuclease (PARN) by purine nucleotides: kinetic analysis. Journal of enzyme inhibition and medicinal chemistry 20090401
Severe combined immunodeficiency (SCID) and attention deficit hyperactivity disorder (ADHD) associated with a Coronin-1A mutation and a chromosome 16p11.2 deletion. Clinical immunology (Orlando, Fla.) 20090401
Fragmentation of isomeric intrastrand crosslink lesions of DNA in an ion-trap mass spectrometer. Journal of the American Society for Mass Spectrometry 20090401
Extracellular guanosine and GTP promote expression of differentiation markers and induce S-phase cell-cycle arrest in human SH-SY5Y neuroblastoma cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20090401
Elucidation of the substrate specificity, kinetic and catalytic mechanism of adenylosuccinate lyase from Plasmodium falciparum. Biochimica et biophysica acta 20090401
2007 annual progress report synopsis of the Center for Structures of Membrane Proteins. Journal of structural and functional genomics 20090401
Metabolism-blocked antifolates as potential anti-rheumatoid arthritis agents: 4-amino-4-deoxy-5,8,10-trideazapteroyl-d,l-4'-methyleneglutamic acid (CH-1504) and its analogs. Biochemical pharmacology 20090401
The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines. Biochemical pharmacology 20090401
Inhibiting the teratogenicity of the immunosuppressant leflunomide in mice by supplementation of exogenous uridine. Toxicological sciences : an official journal of the Society of Toxicology 20090401
Differential proteomic analysis of lymphocytes treated with mycophenolic acid reveals caspase 3-induced cleavage of rho GDP dissociation inhibitor 2. Therapeutic drug monitoring 20090401
Phenotypes of mutations in the 5'-UTR of a limiting transcription factor in Aspergillus nidulans can be accounted for by translational inhibition and leaky scanning. Genetics 20090401
Transgenic expression of human equilibrative nucleoside transporter 1 in mouse neurons. Journal of neurochemistry 20090401
The purine nucleosides adenosine and guanosine delay axonal degeneration in vitro. Journal of neurochemistry 20090401
Incorporation of an inducible nucleotide analog into DNA by DNA polymerases. Bioorganic & medicinal chemistry 20090401
Immunophenotypic analysis of CD103+ B-lymphoproliferative disorders: hairy cell leukemia and its mimics. American journal of clinical pathology 20090401
Inborn errors of purine and pyrimidine metabolism. Journal of inherited metabolic disease 20090401
Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase. The FEBS journal 20090401
Time-of-flight mass spectrometry (TOF-MS) exact mass database for benzodiazepine screening. Legal medicine (Tokyo, Japan) 20090401
Regulation of Acanthamoeba castellanii alternative oxidase activity by mutual exclusion of purine nucleotides; ATP's inhibitory effect. Biochimica et biophysica acta 20090401
Drug induction apoptosis assay as predictive value of chemotherapy response in patients with B-cell chronic lymphocytic leukemia. Leukemia & lymphoma 20090401
Roles of purines in synaptic modulation evoked by hypercapnia in isolated spinal cord of neonatal rat in vitro. British journal of pharmacology 20090401
A cell cycle timer for asymmetric spindle positioning. PLoS biology 20090401
Inhibition studies of bovine xanthine oxidase by luteolin, silibinin, quercetin, and curcumin. Journal of natural products 20090401
Increased levels of 8-hydroxydeoxyguanosine and malondialdehyde and its relationship with antioxidant enzymes in saliva of periodontitis patients. European journal of dentistry 20090401
Functional properties of the Ustilago maydis alternative oxidase under oxidative stress conditions. Mitochondrion 20090401
[Genetic control of metabolism of mutagenic purine base analogs 6-hydroxylaminopurine and 2-amino-6-hydroxylaminopurine in yeast Saccharomyces cerevisiae]. Genetika 20090401
Etiology and management of tumor lysis syndrome in patients with chronic lymphocytic leukemia. Clinical advances in hematology & oncology : H&O 20090401
Febuxostat: new drug. Hyperuricaemia: risk of gout attacks. Prescrire international 20090401
The comparative study digestion and metabolism of nitrogen and purine derivatives in male, Thai, Swamp buffalo and Thai, Brahman cattle. Animal science journal = Nihon chikusan Gakkaiho 20090401
Anaesthesia for renal transplantation: an update. Indian journal of anaesthesia 20090401
Recovery of intravenously infused chromium EDTA and lithium sulphate in the urine of cattle and their use as markers to measure urine volume. Animal : an international journal of animal bioscience 20090401
Substrate Orientation and Catalysis at the Molybdenum Site in Xanthine Oxidase: CRYSTAL STRUCTURES IN COMPLEX WITH XANTHINE AND LUMAZINE. The Journal of biological chemistry 20090327
TFIIH and P-TEFb coordinate transcription with capping enzyme recruitment at specific genes in fission yeast. Molecular cell 20090327
Thermus thermophilus strains active in purine nucleoside synthesis. Molecules (Basel, Switzerland) 20090324
Current status of older and new purine nucleoside analogues in the treatment of lymphoproliferative diseases. Molecules (Basel, Switzerland) 20090323
Enantiodivergent synthesis of cyclohexenyl nucleosides. The Journal of organic chemistry 20090320
Fluorescence emission properties of 8-aza analogues of caffeine, theophylline, and related N-alkyl xanthines. Bioorganic & medicinal chemistry 20090315
New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine. Journal of medicinal chemistry 20090312
Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG). Biochemistry 20090310
Resonance-enhanced multiphoton ionisation of purine. Chemphyschem : a European journal of chemical physics and physical chemistry 20090309
A novel polymorphic purine complex at the 1.5 kb upstream region of the human caveolin-1 gene and risk of Alzheimer's disease; extra-short alleles and accumulated allele homozygosity. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20090305
Quenching of the fluorescence of aromatic pterins by deoxynucleotides. The journal of physical chemistry. A 20090305
Conformational equilibria of bulged sites in duplex DNA studied by EPR spectroscopy. The journal of physical chemistry. B 20090305
Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver. Physiological genomics 20090303
Synthesis and pharmacological characterization of [(125)I]MRS1898, a high-affinity, selective radioligand for the rat A(3) adenosine receptor. Purinergic signalling 20090301
Structure-activity relationships of anthraquinone derivatives derived from bromaminic acid as inhibitors of ectonucleoside triphosphate diphosphohydrolases (E-NTPDases). Purinergic signalling 20090301
Development of selective agonists and antagonists of P2Y receptors. Purinergic signalling 20090301
Preface: special issue on medicinal chemistry of purines. Purinergic signalling 20090301
Non-hemic autoimmunity in CLL. Leukemia research 20090301
Treatment of B-cell chronic lymphocytic leukemia with nonchemotherapeutic agents: experience with single-agent and combination therapy. Leukemia 20090301
Influence of different levels of concentrate and ruminally undegraded protein on digestive variables in beef heifers. Journal of animal science 20090301
Molecular analysis of the interaction of anthrax adenylyl cyclase toxin, edema factor, with 2'(3')-O-(N-(methyl)anthraniloyl)-substituted purine and pyrimidine nucleotides. Molecular pharmacology 20090301
Long-term follow-up of interferon-alpha induction and low-dose maintenance therapy in hairy cell leukemia. European journal of haematology 20090301
Proteomic analysis of human macrophages exposed to hypochlorite-oxidized low-density lipoprotein. Biochimica et biophysica acta 20090301
Biochemical characterization and homology modeling of a purine-specific ribonucleoside hydrolase from the archaeon Sulfolobus solfataricus: insights into mechanisms of protein stabilization. Archives of biochemistry and biophysics 20090301
Inhibition of cancer cell growth by ruthenium(II) cyclopentadienyl derivative complexes with heteroaromatic ligands. Journal of inorganic biochemistry 20090301
Allantoate amidohydrolase transcript expression is independent of drought tolerance in soybean. Journal of experimental botany 20090301
Guanosine and synthetic organoselenium compounds modulate methylmercury-induced oxidative stress in rat brain cortical slices: involvement of oxidative stress and glutamatergic system. Toxicology in vitro : an international journal published in association with BIBRA 20090301
Methylene tetrahydrofolate dehydrogenase/cyclohydrolase and the synthesis of 10-CHO-THF are essential in Leishmania major. Molecular microbiology 20090301
Recent improvements in the development of A(2B) adenosine receptor agonists. Purinergic signalling 20090301
Hepatosplenic T-cell lymphomas and therapy with TNF-alpha-blocking biologics: a risk for psoriasis patients? Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20090301
Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains. ChemMedChem 20090301
Phylogenetic analysis and molecular evolution of guanine deaminases: from guanine to dendrites. Journal of molecular evolution 20090301
Purinergic signaling in special senses. Trends in neurosciences 20090301
Technical note: A new high-performance liquid chromatography purine assay for quantifying microbial flow. Journal of dairy science 20090301
Characterization of nucleobase transport by mouse Sertoli cell line TM4. Biological & pharmaceutical bulletin 20090301
Prolonged myelosuppression with clofarabine in the treatment of patients with relapsed or refractory, aggressive non-Hodgkin lymphoma. Leukemia & lymphoma 20090301
T-cell prolymphocytic leukemia. Expert review of anticancer therapy 20090301
Molecular and biological aspects of antimalarial resistance in Plasmodium falciparum and Plasmodium vivax. Current drug targets 20090301
O6-(benzotriazol-1-yl)inosine derivatives for C6 modification of purine nucleosides. Current protocols in nucleic acid chemistry 20090301
Stereoselective approach to the Z-isomers of methylenecyclopropane analogues of nucleosides: a new synthesis of antiviral synguanol. Nucleosides, nucleotides & nucleic acids 20090301
Purine nucleotide catabolism in rat liver. Certain preliminary aspects of uricase reaction. Nucleosides, nucleotides & nucleic acids 20090301
Fludarabine-based combination therapies for Waldenström's macroglobulinemia. Clinical lymphoma & myeloma 20090301
Regulation of pyrimidine formation in Pseudomonas lundensis. Canadian journal of microbiology 20090301
Role of metal oxides in chemical evolution: interaction of ribose nucleotides with alumina. Astrobiology 20090301
[Clinical analysis of 15 patients with Waldenstrom macroglobulinemia]. Zhonghua nei ke za zhi 20090301
Sod2 haploinsufficiency does not accelerate aging of telomere dysfunctional mice. Aging 20090301
Synthesis of labeled BCX-4208, a potent inhibitor of purine nucleoside phosphorylase. Drug testing and analysis 20090301
Third-generation immucillins: syntheses and bioactivities of acyclic immucillin inhibitors of human purine nucleoside phosphorylase. Journal of medicinal chemistry 20090226
Measurement of oxidative DNA damage induced by mainstream cigarette smoke in cultured NCI-H292 human pulmonary carcinoma cells. Mutation research 20090219
Reaction of hydrated electrons with guanine derivatives: tautomerism of intermediate species. The journal of physical chemistry. B 20090219
Theoretical analysis on the transition state of the anticancer drug trans-[PtCl2(isopropylamine)2] and its cis isomer binding to DNA purine bases. The journal of physical chemistry. B 20090219
Synthesis and antimicrobial evaluation of some new substituted purine derivatives. Bioorganic & medicinal chemistry 20090215
'Conditional Restraints': Restraining the Free Atoms in ARP/wARP. Structure (London, England : 1993) 20090213
The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis. The Journal of biological chemistry 20090206
Oxidation and glycolytic cleavage of etheno and propano DNA base adducts. Biochemistry 20090203
Growth pattern and partial proteome of Mycobacterium avium subsp. paratuberculosis during the stress response to hypoxia and nutrient starvation. Veterinary microbiology 20090202
Ab initio study of the interactions between CO(2) and N-containing organic heterocycles. Chemphyschem : a European journal of chemical physics and physical chemistry 20090202
Debris clearance by microglia: an essential link between degeneration and regeneration. Brain : a journal of neurology 20090201
Isolation and characterization of a novel adenosine deaminase inhibitor, IADA-7, from Bacillus sp. J-89. Journal of enzyme inhibition and medicinal chemistry 20090201
Calorimetric study as a potential test for choosing treatment of B-cell chronic lymphocytic leukemia. Leukemia research 20090201
The origin and evolution of modern metabolism. The international journal of biochemistry & cell biology 20090201
Effects of forage:concentrate ratio and forage type on apparent digestibility, ruminal fermentation, and microbial growth in goats. Journal of animal science 20090201
Rumen fermentation, microbial protein synthesis, and nutrient flow to the omasum in cattle offered corn silage, grass silage, or whole-crop wheat. Journal of animal science 20090201
Two novel nucleobase/pentamidine transporters from Trypanosoma brucei. Molecular and biochemical parasitology 20090201
Correlations of six related purine metabolites and diabetic nephropathy in Chinese type 2 diabetic patients. Clinical biochemistry 20090201
Outcomes of methotrexate therapy for psoriasis and relationship to genetic polymorphisms. The British journal of dermatology 20090201
Occurrence of theobromine synthase genes in purine alkaloid-free species of Camellia plants. Planta 20090201
Pharmacological characterization of pannexin-1 currents expressed in mammalian cells. The Journal of pharmacology and experimental therapeutics 20090201
Structural insights into the inhibited states of the Mer receptor tyrosine kinase. Journal of structural biology 20090201
Successful treatment of refractory polymyositis with the immunosuppressant mizoribine: case report. Clinical rheumatology 20090201
Selective fluorescence quenching of the 8-oxoG-clamp by 8-oxodeoxyguanosine in ODN. Bioorganic & medicinal chemistry letters 20090201
Synthesis of bicyclic N-arylmethyl-substituted iminoribitol derivatives as selective nucleoside hydrolase inhibitors. ChemMedChem 20090201
Predicting gene expression level from relative codon usage bias: an application to Escherichia coli genome. DNA research : an international journal for rapid publication of reports on genes and genomes 20090201
Generation of an improved foamy virus vector by dissection of cis-acting sequences. The Journal of general virology 20090201
The role of diet in the management of gout: a comparison of knowledge and attitudes to current evidence. Journal of human nutrition and dietetics : the official journal of the British Dietetic Association 20090201
Purines and oxypurines in myocardial ischemia. Saudi medical journal 20090201
Articular chondrocytes express connexin 43 hemichannels and P2 receptors - a putative mechanoreceptor complex involving the primary cilium? Journal of anatomy 20090201
A genome-scale metabolic reconstruction of Mycoplasma genitalium, iPS189. PLoS computational biology 20090201
[Genetic diversity and origin of mitochondria DNA D-loop region of some Chinese indigenous cattle breeds]. Yi chuan = Hereditas 20090201
2-(1-Adamant-yl)-1-{4-[(2-chloro-9-isopropyl-9H-purin-6-yl)amino-meth-yl]phen-yl}ethanone. Acta crystallographica. Section E, Structure reports online 20090201
Gene therapy for immunodeficiency due to adenosine deaminase deficiency. The New England journal of medicine 20090129
Folate and colorectal cancer prevention. British journal of cancer 20090127
A structural basis for the recognition of 2'-deoxyguanosine by the purine riboswitch. Journal of molecular biology 20090123
Identification of bacteriophage N4 virion RNA polymerase-nucleic acid interactions in transcription complexes. The Journal of biological chemistry 20090123
AtAzg1 and AtAzg2 comprise a novel family of purine transporters in Arabidopsis. FEBS letters 20090122
Translesion DNA synthesis by human DNA polymerase eta on templates containing a pyrimidopurinone deoxyguanosine adduct, 3-(2'-deoxy-beta-d-erythro-pentofuranosyl)pyrimido-[1,2-a]purin-10(3H)-one. Biochemistry 20090120
Mutations in the Chinese hamster ovary cell GART gene of de novo purine synthesis. Gene 20090115
5,10-Methenyltetrahydrofolate synthetase activity is increased in tumors and modifies the efficacy of antipurine LY309887. Archives of biochemistry and biophysics 20090115
Interrogating the mechanism of a tight binding inhibitor of AIR carboxylase. Bioorganic & medicinal chemistry 20090115
Structure of the nucleotide radical formed during reaction of CDP/TTP with the E441Q-alpha2beta2 of E. coli ribonucleotide reductase. Journal of the American Chemical Society 20090114
Role of the 2-amino group of purines during dNTP polymerization by human DNA polymerase alpha. Biochemistry 20090113
Accommodation of an N-(deoxyguanosin-8-yl)-2-acetylaminofluorene adduct in the active site of human DNA polymerase iota: Hoogsteen or Watson-Crick base pairing? Biochemistry 20090113
Properties and reactivity of the adenosine radical generated by radiation-induced oxidation in aqueous solution. The journal of physical chemistry. B 20090108
Insight into mechanism of formation of c8 adducts in carcinogenic reactions of arylnitrenium ions with purine nucleosides. The journal of physical chemistry. B 20090108
A new role for cisplatin: probing ribosomal RNA structure. Chemical communications (Cambridge, England) 20090107
Products and substrate/template usage of vaccinia virus DNA primase. Virology 20090105
Nicotinamide riboside and nicotinic acid riboside salvage in fungi and mammals. Quantitative basis for Urh1 and purine nucleoside phosphorylase function in NAD+ metabolism. The Journal of biological chemistry 20090102
Cloning and pharmacological characterization of a novel gene encoding human nucleoside transporter 1 (hNT1) from a human breast cancer cDNA library. Life sciences 20090102
Adenosine receptor modulation: potential implications in veterinary medicine. Veterinary journal (London, England : 1997) 20090101
Bovine endometrial legumain and TIMP-2 regulation in response to presence of a conceptus. Molecular reproduction and development 20090101
Uric acid: A marker of increased cardiovascular risk. Atherosclerosis 20090101
Characterisation of ATP analogues to cross-link and label P2X receptors. Neuropharmacology 20090101
Rapid hepatic fate specification of adipose-derived stem cells and their therapeutic potential for liver failure. Journal of gastroenterology and hepatology 20090101
Lessons from comparative physiology: could uric acid represent a physiologic alarm signal gone awry in western society? Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20090101
Efficacy of the tubercidin antileishmania action associated with an inhibitor of the nucleoside transport. Parasitology research 20090101
Neuroeffector Ca2+ transients for the direct measurement of purine release and indirect measurement of cotransmitters in rodents. Experimental physiology 20090101
Purification and partial characterization of the xanthine-uric acid transporter (UapA) of Aspergillus nidulans. Protein expression and purification 20090101
Double-stranded RNA specific to adenosine kinase and hypoxanthine-xanthine-guanine-phosphoribosyltransferase retards growth of Toxoplasma gondii. Parasitology research 20090101
Temporal proteomic analysis of intestine developing necrotizing enterocolitis following enteral formula feeding to preterm pigs. Journal of proteome research 20090101
Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells. British journal of haematology 20090101
Purinergic signalling in the nervous system: an overview. Trends in neurosciences 20090101
2,6,9-Trisubstituted purine derivatives as protein A mimetics for the treatment of autoimmune diseases. Bioorganic & medicinal chemistry letters 20090101
Anaerobic growth promotes synthesis of colonization factors encoded at the Vibrio pathogenicity island in Vibrio cholerae El Tor. Research in microbiology 20090101
Pleuromutilin derivatives having a purine ring. Part 3: synthesis and antibacterial activity of novel compounds possessing a piperazine ring spacer. Bioorganic & medicinal chemistry letters 20090101
Pleuromutilin derivatives having a purine ring. Part 2: influence of the central spacer on the antibacterial activity against Gram-positive pathogens. Bioorganic & medicinal chemistry letters 20090101
The purine derivative PI-55 blocks cytokinin action via receptor inhibition. The FEBS journal 20090101
Changing paradigms in diagnosis of inherited defects associated with urolithiasis. The Veterinary clinics of North America. Small animal practice 20090101
Molecular modelling studies, synthesis and biological activity of a series of novel bisnaphthalimides and their development as new DNA topoisomerase II inhibitors. Bioorganic & medicinal chemistry 20090101
Membrane compartments and purinergic signalling: occurrence and function of P2X receptors in lung. The FEBS journal 20090101
Membrane compartments and purinergic signalling: the purinome, a complex interplay among ligands, degrading enzymes, receptors and transporters. The FEBS journal 20090101
Membrane compartments and purinergic signalling. The FEBS journal 20090101
Mass spectrometry studies of the binding of the minor groove-directed alkylating agent alkamin to AT-tract oligonucleotides. Chemical research in toxicology 20090101
Using profiles based on nucleotide hydrophobicity to define essential regions for splicing. International journal of biological sciences 20090101
Mutational, inhibitory and microcalorimetric analyses of Plasmodium falciparum TMP kinase. Implications for drug discovery. Parasitology 20090101
Gonadal transcriptome alterations in response to dietary energy intake: sensing the reproductive environment. PloS one 20090101
The iron/heme regulated genes of Haemophilus influenzae: comparative transcriptional profiling as a tool to define the species core modulon. BMC genomics 20090101
Molecular evolution of UCP1 and the evolutionary history of mammalian non-shivering thermogenesis. BMC evolutionary biology 20090101
Catalytic inhibition of topoisomerase II by a novel rationally designed ATP-competitive purine analogue. BMC chemical biology 20090101
Molecular time-course and the metabolic basis of entry into dauer in Caenorhabditis elegans. PloS one 20090101
Anti-nociceptive properties of the xanthine oxidase inhibitor allopurinol in mice: role of A1 adenosine receptors. British journal of pharmacology 20090101
Characterization of the meningococcal DNA glycosylase Fpg involved in base excision repair. BMC microbiology 20090101
Kinetic hybrid models composed of mechanistic and simplified enzymatic rate laws--a promising method for speeding up the kinetic modelling of complex metabolic networks. The FEBS journal 20090101
Humanized ADEPT comprised of an engineered human purine nucleoside phosphorylase and a tumor targeting peptide for treatment of cancer. Molecular cancer therapeutics 20090101
Acute exercise and oxidative stress: a 30 year history. Dynamic medicine : DM 20090101
Genome analysis of the anaerobic thermohalophilic bacterium Halothermothrix orenii. PloS one 20090101
Mitochondrial genome sequence and gene order of Sipunculus nudus give additional support for an inclusion of Sipuncula into Annelida. BMC genomics 20090101
Chemical and molecular basis of the carcinogenicity of Aristolochia plants. Current opinion in drug discovery & development 20090101
Evaluation of a microarray-hybridization based method applicable for discovery of single nucleotide polymorphisms (SNPs) in the Pseudomonas aeruginosa genome. BMC genomics 20090101
Tryptophan degradation in irritable bowel syndrome: evidence of indoleamine 2,3-dioxygenase activation in a male cohort. BMC gastroenterology 20090101
Recombinant mouse PAP has pH-dependent ectonucleotidase activity and acts through A(1)-adenosine receptors to mediate antinociception. PloS one 20090101
Metabolomic profiling of drug responses in acute myeloid leukaemia cell lines. PloS one 20090101
Molecular identification of CTX-M and blaOXY/K1 beta-lactamase genes in Enterobacteriaceae by sequencing of universal M13-sequence tagged PCR-amplicons. BMC infectious diseases 20090101
Interplay of Mre11 nuclease with Dna2 plus Sgs1 in Rad51-dependent recombinational repair. PloS one 20090101
A novel function for fragile X mental retardation protein in translational activation. PLoS biology 20090101
Improper excess light energy dissipation in Arabidopsis results in a metabolic reprogramming. BMC plant biology 20090101
Preclinical support for combination therapy in the treatment of autoimmunity with atacicept. Toxicologic pathology 20090101
One ancestor for two codes viewed from the perspective of two complementary modes of tRNA aminoacylation. Biology direct 20090101
Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. Arthritis research & therapy 20090101
Nitrous oxide may not increase the risk of cancer recurrence after colorectal surgery: a follow-up of a randomized controlled trial. BMC anesthesiology 20090101
mRNA stability and the unfolding of gene expression in the long-period yeast metabolic cycle. BMC systems biology 20090101
Analysis of small nucleolar RNAs reveals unique genetic features in malaria parasites. BMC genomics 20090101
MRI findings in 77 children with non-syndromic autistic disorder. PloS one 20090101
Genome-scale analysis to the impact of gene deletion on the metabolism of E. coli: constraint-based simulation approach. BMC bioinformatics 20090101
Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression. International journal of medical sciences 20090101
Use of high-density tiling microarrays to identify mutations globally and elucidate mechanisms of drug resistance in Plasmodium falciparum. Genome biology 20090101
Age and diet affect gene expression profile in canine skeletal muscle. PloS one 20090101
Hematopoietic stem cell gene therapy for adenosine deaminase deficient-SCID. Immunologic research 20090101
Regulating highly dynamic unstructured proteins and their coding mRNAs. Genome biology 20090101
Comparison between the HCV IRES domain IV RNA structure and the Iron Responsive Element. Journal of negative results in biomedicine 20090101
A fragile metabolic network adapted for cooperation in the symbiotic bacterium Buchnera aphidicola. BMC systems biology 20090101
Genome-wide analysis of chicken snoRNAs provides unique implications for the evolution of vertebrate snoRNAs. BMC genomics 20090101
A linear programming approach for estimating the structure of a sparse linear genetic network from transcript profiling data. Algorithms for molecular biology : AMB 20090101
Incorporating double copies of a chromatin insulator into lentiviral vectors results in less viral integrants. BMC biotechnology 20090101
Unique signatures of natural background radiation on human Y chromosomes from Kerala, India. PloS one 20090101
Circulating adhesion molecules and purine nucleotides during kidney allograft reperfusion. Transplantation proceedings 20090101
Essential pathway identification: from in silico analysis to potential antifungal targets in Aspergillus fumigatus. Medical mycology 20090101
Genome sequence of the pathogenic intestinal spirochete brachyspira hyodysenteriae reveals adaptations to its lifestyle in the porcine large intestine. PloS one 20090101
Glutamine deprivation induces abortive s-phase rescued by deoxyribonucleotides in k-ras transformed fibroblasts. PloS one 20090101
Fludarabine modulates immune response and extends in vivo survival of adoptively transferred CD8 T cells in patients with metastatic melanoma. PloS one 20090101
Diverse protein regulations on PHA formation in Ralstonia eutropha on short chain organic acids. International journal of biological sciences 20090101
Nutrition, anabolism, and the wound healing process: an overview. Eplasty 20090101
The action of key factors in protein evolution at high temporal resolution. PloS one 20090101
Aberrant epigenetic silencing is triggered by a transient reduction in gene expression. PloS one 20090101
Reconstruction of metabolic pathways for the cattle genome. BMC systems biology 20090101
Regulation of clock-controlled genes in mammals. PloS one 20090101
Implications of the structure of human uridine phosphorylase 1 on the development of novel inhibitors for improving the therapeutic window of fluoropyrimidine chemotherapy. BMC structural biology 20090101
Genome-wide hypomethylation in head and neck cancer is more pronounced in HPV-negative tumors and is associated with genomic instability. PloS one 20090101
Three new structures of left-handed RADA helical filaments: structural flexibility of N-terminal domain is critical for recombinase activity. PloS one 20090101
Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates. PloS one 20090101
High-throughput proteomics detection of novel splice isoforms in human platelets. PloS one 20090101
Novel insights into iron metabolism by integrating deletome and transcriptome analysis in an iron deficiency model of the yeast Saccharomyces cerevisiae. BMC genomics 20090101
Connecting extracellular metabolomic measurements to intracellular flux states in yeast. BMC systems biology 20090101
Structural studies of PNP from Toxoplasma gondii. International journal of bioinformatics research and applications 20090101
Multifactor dimensionality reduction analysis identifies specific nucleotide patterns promoting genetic polymorphisms. BioData mining 20090101
Synthesis, anticancer and radioprotective activities of some new pyrazolo[3,4-d]pyrimidines containing amino acid moieties. Arzneimittel-Forschung 20090101
The N-terminal domain of Escherichia coli RecA have multiple functions in promoting homologous recombination. Journal of biomedical science 20090101
Prediction of breast cancer by profiling of urinary RNA metabolites using Support Vector Machine-based feature selection. BMC cancer 20090101
How close is the bench to the bedside? Metabolic profiling in cancer research. Genome medicine 20090101
Pxmp2 is a channel-forming protein in Mammalian peroxisomal membrane. PloS one 20090101
Choreography of the transcriptome, photophysiology, and cell cycle of a minimal photoautotroph, prochlorococcus. PloS one 20090101
Constraint-based analysis of metabolic capacity of Salmonella typhimurium during host-pathogen interaction. BMC systems biology 20090101
Deciphering peculiar protein-protein interacting modules in Deinococcus radiodurans. Biology direct 20090101
The p53HMM algorithm: using profile hidden markov models to detect p53-responsive genes. BMC bioinformatics 20090101
Enzymatic ligation strategies for the preparation of purine riboswitches with site-specific chemical modifications. Methods in molecular biology (Clifton, N.J.) 20090101
Gene composer: database software for protein construct design, codon engineering, and gene synthesis. BMC biotechnology 20090101
Transcriptomic and metabolic responses of Staphylococcus aureus exposed to supra-physiological temperatures. BMC microbiology 20090101
Comparative study of the persistence of anti-HIV activity of deoxynucleoside HIV reverse transcriptase inhibitors after removal from culture. AIDS research and therapy 20090101
Dietary intake of folate, vitamin B6, and vitamin B12, genetic polymorphism of related enzymes, and risk of breast cancer: a case-control study in Brazilian women. BMC cancer 20090101
Detection of biochemical pathways by probabilistic matching of phyletic vectors. PloS one 20090101
[In vitro biological activity of new platinum(II) and palladium(II) complex compounds]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20090101
Molecular profiles of Quadriceps muscle in myostatin-null mice reveal PI3K and apoptotic pathways as myostatin targets. BMC genomics 20090101
Site directed mutagenesis of amino acid residues at the active site of mouse aldehyde oxidase AOX1. PloS one 20090101
Using in silico models to simulate dual perturbation experiments: procedure development and interpretation of outcomes. BMC systems biology 20090101
Co-evolutionary networks of genes and cellular processes across fungal species. Genome biology 20090101
A high speed detection platform based on surface-enhanced Raman scattering for monitoring antibiotic-induced chemical changes in bacteria cell wall. PloS one 20090101
Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection model. PloS one 20090101
Resolution of tongue lesions caused by Leishmania infantum in a dog treated with the association miltefosine-allopurinol. Parasites & vectors 20090101
Gene expression in murine mammary epithelial stem cell-like cells shows similarities to human breast cancer gene expression. Breast cancer research : BCR 20090101
[Astrobiological investigations on board Russian space crafts]. Tsitologiia 20090101
Mycophenolate mofetil: safety and efficacy in the prophylaxis of acute kidney transplantation rejection. Therapeutics and clinical risk management 20090101
Fludarabine in the treatment of chronic lymphocytic leukemia: a review. Therapeutics and clinical risk management 20090101
Role of urate, xanthine oxidase and the effects of allopurinol in vascular oxidative stress. Vascular health and risk management 20090101
Genome degradation in Brucella ovis corresponds with narrowing of its host range and tissue tropism. PloS one 20090101
Characterizing structural transitions using localized free energy landscape analysis. PloS one 20090101
Prediction of mono- and di-nucleotide-specific DNA-binding sites in proteins using neural networks. BMC structural biology 20090101
The role of intrinsically unstructured proteins in neurodegenerative diseases. PloS one 20090101
Effects of low-dose mizoribine pulse therapy in combination with methotrexate in rheumatoid arthritis patients with an insufficient response to methotrexate. Modern rheumatology 20090101
Proteomic and network analysis characterize stage-specific metabolism in Trypanosoma cruzi. BMC systems biology 20090101
Gene organization and sequence analyses of transfer RNA genes in Trypanosomatid parasites. BMC genomics 20090101
Initiation codon mutation in betaB1-crystallin (CRYBB1) associated with autosomal recessive nuclear pulverulent cataract. Molecular vision 20090101
Insights into the evolution of sialic acid catabolism among bacteria. BMC evolutionary biology 20090101
The genome sequence of Geobacter metallireducens: features of metabolism, physiology and regulation common and dissimilar to Geobacter sulfurreducens. BMC microbiology 20090101
Genetic polymorphisms of thiopurine S-methyltransferase in a cohort of patients with systemic autoimmune diseases. Clinical and experimental rheumatology 20090101
Cooperation between apoptotic and viable metacyclics enhances the pathogenesis of Leishmaniasis. PloS one 20090101
Selective killing of tumors deficient in methylthioadenosine phosphorylase: a novel strategy. PloS one 20090101
Cytokine-dependent and-independent gene expression changes and cell cycle block revealed in Trypanosoma cruzi-infected host cells by comparative mRNA profiling. BMC genomics 20090101
What epidemiology has told us about risk factors and aetiopathogenesis in rheumatic diseases. Arthritis research & therapy 20090101
Structure of human DNA polymerase kappa inserting dATP opposite an 8-OxoG DNA lesion. PloS one 20090101
Genomic characterization of methanomicrobiales reveals three classes of methanogens. PloS one 20090101
96 shRNAs designed for maximal coverage of HIV-1 variants. Retrovirology 20090101
T-REX: software for the processing and analysis of T-RFLP data. BMC bioinformatics 20090101
Human T cell recognition of the blood stage antigen Plasmodium hypoxanthine guanine xanthine phosphoribosyl transferase (HGXPRT) in acute malaria. Malaria journal 20090101
Targeted treatment of acute myeloid leukemia in older adults: role of gemtuzumab ozogamicin. Clinical interventions in aging 20090101
[Involvement of angiotensin on adenosine-induced bronchial hyperreactivity]. Pneumologia (Bucharest, Romania) 20090101
The repertoire of G-protein-coupled receptors in Xenopus tropicalis. BMC genomics 20090101
SHMT1 and SHMT2 are functionally redundant in nuclear de novo thymidylate biosynthesis. PloS one 20090101
Structural and phylogenetic analysis of a conserved actinobacteria-specific protein (ASP1; SCO1997) from Streptomyces coelicolor. BMC structural biology 20090101
Novel drugs for chronic lymphoid leukemias: mechanism of action and therapeutic activity. Current medicinal chemistry 20090101
Mesothelioma: Do asbestos and carbon nanotubes pose the same health risk? Particle and fibre toxicology 20090101
Insights into the role of Val45 and Gln182 of Escherichia coli MutY in DNA substrate binding and specificity. BMC biochemistry 20090101
[Peculiarities of uric acid balance disorders in patients with type 2 diabetes and metabolic syndrome]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20090101
Length and sequence heterogeneity in the mitochondrial internal transcribed spacer of Acanthamoeba spp. The Journal of eukaryotic microbiology 20090101
NTPDases in the neuroendocrine hypothalamus: possible energy regulators of the positive gonadotrophin feedback. Reproductive biology and endocrinology : RB&E 20090101
Gamma-MYN: a new algorithm for estimating Ka and Ks with consideration of variable substitution rates. Biology direct 20090101
Global expression analysis of the brown alga Ectocarpus siliculosus (Phaeophyceae) reveals large-scale reprogramming of the transcriptome in response to abiotic stress. Genome biology 20090101
Statistical assessment of discriminative features for protein-coding and non coding cross-species conserved sequence elements. BMC bioinformatics 20090101
Recent advances in biomedical applications of accelerator mass spectrometry. Journal of biomedical science 20090101
A single transcription factor regulates evolutionarily diverse but functionally linked metabolic pathways in response to nutrient availability. Molecular systems biology 20090101
[Antibodies to enzymes of purine metabolism as a factor of gastrointestinal tract lesions in systemic scleroderma]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20090101
Genome analysis and genome-wide proteomics of Thermococcus gammatolerans, the most radioresistant organism known amongst the Archaea. Genome biology 20090101
Metabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathway. PloS one 20090101
Transcriptome adaptation of group B Streptococcus to growth in human amniotic fluid. PloS one 20090101
Joint Arthroplasties other than the Hip in Solid Organ Transplant Recipients. The open orthopaedics journal 20090101
Conservation of structure and activity in Plasmodium purine nucleoside phosphorylases. BMC structural biology 20090101
The complex regulation of HIC (Human I-mfa domain containing protein) expression. PloS one 20090101
Systemic treatment of xenografts with vaccinia virus GLV-1h68 reveals the immunologic facet of oncolytic therapy. BMC genomics 20090101
Purine nucleoside phosphorylase deficiency in two unrelated Saudi patients. Annals of Saudi medicine 20090101
Differential effects of iodoacetamide and iodoacetate on glycolysis and glutathione metabolism of cultured astrocytes. Frontiers in neuroenergetics 20090101
Exploring temporal transcription regulation structure of Aspergillus fumigatus in heat shock by state space model. BMC genomics 20090101
In Vitro Evaluation of Oxoplatin: An Oral Platinum(IV) Anticancer Agent. Metal-based drugs 20090101
Oxidative stress, thermogenesis and evolution of uncoupling proteins. Journal of biology 20090101
Comparing 2-nt 3' overhangs against blunt-ended siRNAs: a systems biology based study. BMC genomics 20090101
Word-based characterization of promoters involved in human DNA repair pathways. BMC genomics 20090101
Gene expression responses in male fathead minnows exposed to binary mixtures of an estrogen and antiestrogen. BMC genomics 20090101
Dynamic expression pattern of distinct genes in the presomitic and somitic mesoderm during Xenopus development. The International journal of developmental biology 20090101
Regression based predictor for p53 transactivation. BMC bioinformatics 20090101
Cross-packaging of genetically distinct mouse and primate retroviral RNAs. Retrovirology 20090101
Ticagrelor: the first reversibly binding oral P2Y12 receptor antagonist. Cardiovascular therapeutics 20090101
Do uric acid deposits in zooxanthellae function as eye-spots? PloS one 20090101
Update in the management of chronic lymphocytic leukemia. Journal of hematology & oncology 20090101
Bacillus subtilis as potential producer for polyhydroxyalkanoates. Microbial cell factories 20090101
DNA binding by Corynebacterium glutamicum TetR-type transcription regulator AmtR. BMC molecular biology 20090101
The activities of paraoxonase, xanthine oxidase, adenosine deaminase and the level of nitrite in pseudoexfoliation syndrome. Ophthalmic research 20090101
The first cellular models based on frataxin missense mutations that reproduce spontaneously the defects associated with Friedreich ataxia. PloS one 20090101
Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis. Arthritis research & therapy 20090101
Hidden chromosome symmetry: in silico transformation reveals symmetry in 2D DNA walk trajectories of 671 chromosomes. PloS one 20090101
Bacillus cereus spores release alanine that synergizes with inosine to promote germination. PloS one 20090101
Adenosine receptors and neurological disease: neuroprotection and neurodegeneration. Handbook of experimental pharmacology 20090101
Assessment of the effect of betaine on p16 and c-myc DNA methylation and mRNA expression in a chemical induced rat liver cancer model. BMC cancer 20090101
Hydrogen bonding and packing density are factors most strongly connected to limiting sites of high flexibility in the 16S rRNA in the 30S ribosome. BMC structural biology 20090101
Stretches of alternating pyrimidine/purines and purines are respectively linked with pathogenicity and growth temperature in prokaryotes. BMC genomics 20090101
Global effect of RpoS on gene expression in pathogenic Escherichia coli O157:H7 strain EDL933. BMC genomics 20090101
Candidate pathways and genes for prostate cancer: a meta-analysis of gene expression data. BMC medical genomics 20090101
Genome-wide profile of pleural mesothelioma versus parietal and visceral pleura: the emerging gene portrait of the mesothelioma phenotype. PloS one 20090101
Gene expression profiling in equine polysaccharide storage myopathy revealed inflammation, glycogenesis inhibition, hypoxia and mitochondrial dysfunctions. BMC veterinary research 20090101
Regulation of MicroRNA Biogenesis: A miRiad of mechanisms. Cell communication and signaling : CCS 20090101
Ligand scaffold hopping combining 3D maximal substructure search and molecular similarity. BMC bioinformatics 20090101
Genome-wide screen of genes required for caffeine tolerance in fission yeast. PloS one 20090101
Evaluating graft function in pediatric recipients for living donor renal transplantation: Is laparoscopic donor nephrectomy safe? Indian journal of urology : IJU : journal of the Urological Society of India 20090101
MouseCyc: a curated biochemical pathways database for the laboratory mouse. Genome biology 20090101
Advances in maize genomics and their value for enhancing genetic gains from breeding. International journal of plant genomics 20090101
Genome-scale gene/reaction essentiality and synthetic lethality analysis. Molecular systems biology 20090101
Pharmacokinetic optimization of immunosuppressive therapy in thoracic transplantation: part I. Clinical pharmacokinetics 20090101
Genetic and molecular basis of individual differences in human umami taste perception. PloS one 20090101
On the origin of life in the zinc world: 1. Photosynthesizing, porous edifices built of hydrothermally precipitated zinc sulfide as cradles of life on Earth. Biology direct 20090101
Management strategies for pulmonary sarcoidosis. Therapeutics and clinical risk management 20090101
Managing pediatric hepatitis C: current and emerging treatment options. Therapeutics and clinical risk management 20090101
Gene targeted therapeutics for liver disease in alpha-1 antitrypsin deficiency. Biologics : targets & therapy 20090101
Pegademase bovine (PEG-ADA) for the treatment of infants and children with severe combined immunodeficiency (SCID). Biologics : targets & therapy 20090101
Chemotherapy of human african trypanosomiasis. Interdisciplinary perspectives on infectious diseases 20090101
MECP2 isoform-specific vectors with regulated expression for Rett syndrome gene therapy. PloS one 20090101
Preparation of group I introns for biochemical studies and crystallization assays by native affinity purification. PloS one 20090101
Activities of adenosine deaminase and 5'-nucleotidase in cancereous and non-cancereous human gastric tissues. Bratislavske lekarske listy 20090101
Empirical relationship between intra-purine and intra-pyrimidine differences in conserved gene sequences. PloS one 20090101
Intrinsic and extrinsic factors influencing the clinical course of B-cell chronic lymphocytic leukemia: prognostic markers with pathogenetic relevance. Journal of translational medicine 20090101
A lentivirus-mediated genetic screen identifies dihydrofolate reductase (DHFR) as a modulator of beta-catenin/GSK3 signaling. PloS one 20090101
Leptin contributes to the adaptive responses of mice to high-fat diet intake through suppressing the lipogenic pathway. PloS one 20090101
Targeting the purinome. Methods in molecular biology (Clifton, N.J.) 20090101
Sequence features associated with microRNA strand selection in humans and flies. BMC genomics 20090101
Synthesis, spectroscopic and thermal characterization of copper(II) and iron(III) complexes of folic acid and their absorption efficiency in the blood. Bioinorganic chemistry and applications 20090101
Adenosine and adenosine receptors: their contribution to airway inflammation and therapeutic potential in asthma. Current medicinal chemistry 20090101
Idiopathic recurrent calcium urolithiasis (IRCU): variation of fasting urinary protein is a window to pathophysiology or simple consequence of renal stones in situ? A tripartite study in male patients providing insight into oxidative metabolism as possible driving force towards alteration of urine composition, calcium salt crystallization and stone formation. European journal of medical research 20090101
Alternative I-D exchange reaction on pyrimidine and purine nuclei mediated by tributyltin hydride using THF-d8 as a deuterium source. Nucleic acids symposium series (2004) 20090101
Mycophenolic acid formulations in adult renal transplantation - update on efficacy and tolerability. Therapeutics and clinical risk management 20090101
Involvement of A(1) adenosine receptors in osmotic volume regulation of retinal glial cells in mice. Molecular vision 20090101
Gene networks in Drosophila melanogaster: integrating experimental data to predict gene function. Genome biology 20090101
The NlpD lipoprotein is a novel Yersinia pestis virulence factor essential for the development of plague. PloS one 20090101
Time-resolved transcriptome analysis of Bacillus subtilis responding to valine, glutamate, and glutamine. PloS one 20090101
Alterations in adenylate kinase activity in human PBMCs after in vitro exposure to electromagnetic field: comparison between extremely low frequency electromagnetic field (ELF) and therapeutic application of a musically modulated electromagnetic field (TAMMEF). Journal of biomedicine & biotechnology 20090101
Fibroblasts from patients with Diamond-Blackfan anaemia show abnormal expression of genes involved in protein synthesis, amino acid metabolism and cancer. BMC genomics 20090101
Synergistic role of hydroxyapatite nanoparticles and pulsed electromagnetic field therapy to prevent bone loss in rats following exposure to simulated microgravity. International journal of nanomedicine 20090101
A secretory phospholipase A2-mediated neuroprotection and anti-apoptosis. BMC neuroscience 20090101
T-cell prolymphocytic leukemia. Clinical lymphoma & myeloma 20090101
Immunomodulation with methotrexate: underused and undervalued? Digestive diseases (Basel, Switzerland) 20090101
Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. PloS one 20090101
Carbohydrate metabolism and carbon fixation in Roseobacter denitrificans OCh114. PloS one 20090101
Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. BMC genomics 20090101
Draft genome sequence of the Daphnia pathogen Octosporea bayeri: insights into the gene content of a large microsporidian genome and a model for host-parasite interactions. Genome biology 20090101
SigWinR; the SigWin-detector updated and ported to R. BMC research notes 20090101
Refinement of lentiviral vector for improved RNA processing and reduced rates of self inactivation repair. BMC biotechnology 20090101
A man-made ATP-binding protein evolved independent of nature causes abnormal growth in bacterial cells. PloS one 20090101
KEGGconverter: a tool for the in-silico modelling of metabolic networks of the KEGG Pathways database. BMC bioinformatics 20090101
Riboswitch detection using profile hidden Markov models. BMC bioinformatics 20090101
Environmental and intracellular regulation of Francisella tularensis ripA. BMC microbiology 20090101
NK cell-mediated cytotoxicity modulation by A(2) adenosine receptor agonist in different mammalian species. Folia microbiologica 20090101
Differential changes in serum uric acid concentrations in sibutramine promoted weight loss in diabetes: results from four weeks of the lead-in period of the SCOUT trial. Nutrition & metabolism 20090101
Genome-wide transcriptome analyses of silicon metabolism in Phaeodactylum tricornutum reveal the multilevel regulation of silicic acid transporters. PloS one 20090101
Different responsiveness to a high-fat/cholesterol diet in two inbred mice and underlying genetic factors: a whole genome microarray analysis. Nutrition & metabolism 20090101
Elements regulating Potato leafroll virus sgRNA1 translation are located within the coding sequences of the coat protein and read-through domain. Acta biochimica Polonica 20090101
2'-Benzoyloxycinnamaldehyde inhibits tumor growth in H-ras12V transgenic mice via downregulation of metallothionein. Nutrition and cancer 20090101
Arabidopsis gene co-expression network and its functional modules. BMC bioinformatics 20090101
Metabolomic profiling in LRRK2-related Parkinson's disease. PloS one 20090101
Reduction of nitrogen compounds in oceanic basement and its implications for HCN formation and abiotic organic synthesis. Geochemical transactions 20090101
The role of urate and xanthine oxidase in vascular oxidative stress: future directions. Therapeutics and clinical risk management 20090101
Comparative transcriptional survey between laser-microdissected cells from laminar abscission zone and petiolar cortical tissue during ethylene-promoted abscission in citrus leaves. BMC plant biology 20090101
Purine-scaffold Hsp90 inhibitors. Current topics in medicinal chemistry 20090101
The role of UPF0157 in the folding of M. tuberculosis dephosphocoenzyme A kinase and the regulation of the latter by CTP. PloS one 20090101
Hepatic gene expression profiling reveals protective responses in Atlantic salmon vaccinated against furunculosis. BMC genomics 20090101
Effects of methotrexate on plasma cytokines and cardiac remodeling and function in postmyocarditis rats. Mediators of inflammation 20090101
DNA damage/repair and polymorphism of the hOGG1 gene in lymphocytes of AMD patients. Journal of biomedicine & biotechnology 20090101
A genome-wide analysis of small regulatory RNAs in the human pathogen group A Streptococcus. PloS one 20090101
Argonaute2 suppresses Drosophila fragile X expression preventing neurogenesis and oogenesis defects. PloS one 20090101
Lack of association between mutations of gene-encoding mitochondrial D310 (displacement loop) mononucleotide repeat and oxidative stress in chronic dialysis patients in Taiwan. Journal of negative results in biomedicine 20090101
[A theoretical investigation of tautomerism of adenine, purine, guanine, and cytosine]. Biofizika 20090101
SnoRNAs from the filamentous fungus Neurospora crassa: structural, functional and evolutionary insights. BMC genomics 20090101
Current trends in the management of ocular symptoms in Adamantiades-Behçet's disease. Clinical ophthalmology (Auckland, N.Z.) 20090101
Functional phosphoproteomic profiling of phosphorylation sites in membrane fractions of salt-stressed Arabidopsis thaliana. Proteome science 20090101
Reduced levels of reactive oxygen species correlate with inhibition of apoptosis, rise in thioredoxin expression and increased bovine leukemia virus proviral loads. Retrovirology 20090101
Current and emerging treatments for chronic lymphocytic leukaemia. Drugs 20090101
Genome wide evolutionary analyses reveal serotype specific patterns of positive selection in selected Salmonella serotypes. BMC evolutionary biology 20090101
A genome-wide deletion mutant screen identifies pathways affected by nickel sulfate in Saccharomyces cerevisiae. BMC genomics 20090101
Network analysis of the transcriptional pattern of young and old cells of Escherichia coli during lag phase. BMC systems biology 20090101
Analysis of HSP90-related folds with MED-SuMo classification approach. Drug design, development and therapy 20090101
T10B9 monoclonal antibody: a short-acting nonstimulating monoclonal antibody that spares gammadelta T-cells and treats and prevents cellular rejection. Drug design, development and therapy 20090101
Identification of an exonic splicing silencer in exon 6A of the human VEGF gene. BMC molecular biology 20090101
Exceptional error minimization in putative primordial genetic codes. Biology direct 20090101
Partial loss of heterozygosity events at the mutated gene in tumors from MLH1/MSH2 large genomic rearrangement carriers. BMC cancer 20090101
Identifying quantitative operation principles in metabolic pathways: a systematic method for searching feasible enzyme activity patterns leading to cellular adaptive responses. BMC bioinformatics 20090101
Genome-wide analysis of immune activation in human T and B cells reveals distinct classes of alternatively spliced genes. PloS one 20090101
Generation and characterization of FMR1 knockout zebrafish. PloS one 20090101
Ets-2 and p53 mediate cAMP-induced MMP-2 expression, activity and trophoblast invasion. Reproductive biology and endocrinology : RB&E 20090101
Effects of Kombucha on oxidative stress induced nephrotoxicity in rats. Chinese medicine 20090101
JANE: efficient mapping of prokaryotic ESTs and variable length sequence reads on related template genomes. BMC bioinformatics 20090101
Recent advances in the pathogenesis of syndromic autisms. International journal of pediatrics 20090101
Diagnosis of invasive aspergillus tracheobronchitis facilitated by endobronchial ultrasound-guided transbronchial needle aspiration: a case report. Journal of medical case reports 20090101
Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts. BMC genomics 20090101
Purinergic mechanosensory transduction and visceral pain. Molecular pain 20090101
Transcriptomic response of the mycoparasitic fungus Trichoderma atroviride to the presence of a fungal prey. BMC genomics 20090101
Examination of genome homogeneity in prokaryotes using genomic signatures. PloS one 20090101
A genome-wide survey for host response of silkworm, Bombyx mori during pathogen Bacillus bombyseptieus infection. PloS one 20090101
Pathway analysis of GWAS provides new insights into genetic susceptibility to 3 inflammatory diseases. PloS one 20090101
Critical appraisal of the MTT assay in the presence of rottlerin and uncouplers. Biological procedures online 20090101
Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT. Journal of experimental & clinical cancer research : CR 20090101
Drug-induced hematologic syndromes. Advances in hematology 20090101
Combined bezafibrate and medroxyprogesterone acetate: potential novel therapy for acute myeloid leukaemia. PloS one 20090101
Phenotypic characterisation and ZEB1 mutational analysis in posterior polymorphous corneal dystrophy in a New Zealand population. Molecular vision 20090101
Loss of the histone pre-mRNA processing factor stem-loop binding protein in Drosophila causes genomic instability and impaired cellular proliferation. PloS one 20090101
Immune hemolytic anemia--selected topics. Hematology. American Society of Hematology. Education Program 20090101
Allotransplantation for chronic lymphocytic leukemia. Hematology. American Society of Hematology. Education Program 20090101
Influence of sex on gene expression in human corneal epithelial cells. Molecular vision 20090101
Assessing the utility of whole-genome amplified serum DNA for array-based high throughput genotyping. BMC genetics 20090101
The potential for xanthine oxidase inhibition in the prevention and treatment of cardiovascular and cerebrovascular disease. Cardiovascular psychiatry and neurology 20090101
Conservation of DNA-binding specificity and oligomerisation properties within the p53 family. BMC genomics 20090101
Regulation of HIV-1 transcription in cells of the monocyte-macrophage lineage. Retrovirology 20090101
The malate synthase of Paracoccidioides brasiliensis is a linked surface protein that behaves as an anchorless adhesin. BMC microbiology 20090101
Molecular evolution of the hyperthermophilic archaea of the Pyrococcus genus: analysis of adaptation to different environmental conditions. BMC genomics 20090101
Quantitative analysis of replication-related mutation and selection pressures in bacterial chromosomes and plasmids using generalised GC skew index. BMC genomics 20090101
Montelukast does not inhibit the late phase reaction in Parthenium dermatitis. Indian journal of dermatology 20090101
Mizoribine: a new approach in the treatment of renal disease. Clinical & developmental immunology 20090101
Treatment options for ocular adnexal lymphoma (OAL). Clinical ophthalmology (Auckland, N.Z.) 20090101
Development of fludarabine formulations in the treatment of chronic lymphocytic leukemia. Drug design, development and therapy 20090101
Severe encephalopathy with brain atrophy and hypomyelination due to adenylosuccinate lyase deficiency--MRI, clinical, biochemical and neuropathological findings of Polish patients. Folia neuropathologica 20090101
What lies behind serum urate concentration? Insights from genetic and genomic studies. Genome medicine 20090101
A comprehensive review of immunosuppression used for liver transplantation. Journal of transplantation 20090101
Classifying coding DNA with nucleotide statistics. Bioinformatics and biology insights 20090101
Universal Features for the Classification of Coding and Non-coding DNA Sequences. Bioinformatics and biology insights 20090101
Inferring Transcriptional Interactions by the Optimal Integration of ChIP-chip and Knock-out Data. Bioinformatics and biology insights 20090101
Application of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDock. Journal of cheminformatics 20090101
Disease-modifying agents in multiple sclerosis. Annals of Indian Academy of Neurology 20090101
Promising treatments of tomorrow for multiple sclerosis. Annals of Indian Academy of Neurology 20090101
[Hyperuricemia and the metabolic syndrome]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20090101
[Enzymatic transglycosylation of natural and modified nucleosides by immobilized thermostable nucleoside phosphorylases from Geobacillus stearothermophilus]. Bioorganicheskaia khimiia 20090101
2, 8 Dihydroxyadenine urolithiasis: A case report and review of literature. Indian journal of nephrology 20090101
Urate oxidase knockdown decreases oxidative stress in a murine hepatic cell line. Oxidative medicine and cellular longevity 20090101
Immunoregulation through IL-10 gene expression and the fate of cytotoxic T lymphocyte-mediated tumor immunotherapy. Indian journal of human genetics 20090101
mGluR(1) Receptors Contribute to Non-Purinergic Slow Excitatory Transmission to Submucosal VIP Neurons of Guinea-Pig Ileum. Frontiers in neuroscience 20090101
Profile of nelarabine: use in the treatment of T-cell acute lymphoblastic leukemia. OncoTargets and therapy 20090101
Bendamustine in the treatment of non-Hodgkin's lymphomas. OncoTargets and therapy 20090101
Tumor markers in clinical practice: General principles and guidelines. Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology 20090101
Febuxostat: the evidence for its use in the treatment of hyperuricemia and gout. Core evidence 20090101
Oxidative stress as a mediator of cardiovascular disease. Oxidative medicine and cellular longevity 20090101
Purinergic cotransmission. F1000 biology reports 20090101
New oral disease-modifying therapies for multiple sclerosis. F1000 medicine reports 20090101
The role of bendamustine in the treatment of indolent non-Hodgkin lymphoma. Cancer management and research 20090101
A Comparative Study of Metabolic Network Topology between a Pathogenic and a Non-Pathogenic Bacterium for Potential Drug Target Identification. Summit on translational bioinformatics 20090101
Introducing mediterranean journal of hematology and infectious diseases. Mediterranean journal of hematology and infectious diseases 20090101
EBV in Hodgkin Lymphoma. Mediterranean journal of hematology and infectious diseases 20090101
Tacrolimus ointment in the management of atopic dermatitis. Clinical, cosmetic and investigational dermatology 20090101
New concepts of fluorescent probes for specific detection of DNA sequences: bis-modified oligonucleotides in excimer and exciplex detection. The Libyan journal of medicine 20090101
Altered expression of the caffeine synthase gene in a naturally caffeine-free mutant of Coffea arabica. Genetics and molecular biology 20090101
Comparative analysis of the genes UL1 through UL7 of the duck enteritis virus and other herpesviruses of the subfamily Alphaherpesvirinae. Genetics and molecular biology 20090101
Xylella fastidiosa gene expression analysis by DNA microarrays. Genetics and molecular biology 20090101
The glyceraldehyde-3-phosphate dehydrogenase gene of Moniliophthoraperniciosa, the causal agent of witches' broom disease of Theobroma cacao. Genetics and molecular biology 20090101
Escherichia coli, an Intestinal Microorganism, as a Biosensor for Quantification of Amino Acid Bioavailability. Sensors (Basel, Switzerland) 20090101
Effects of malic acid on rumen fermentation, urinary excretion of purine derivatives and feed digestibility in steers. Animal : an international journal of animal bioscience 20090101
Study of Interactions between Metallothionein and Cisplatin by using Differential Pulse Voltammetry Brdickás reaction and Quartz Crystal Microbalance. Sensors (Basel, Switzerland) 20090101
Overview of electrochemical DNA biosensors: new approaches to detect the expression of life. Sensors (Basel, Switzerland) 20090101
The interrelationship of helicase and nuclease domains during DNA translocation by the molecular motor EcoR124I. Journal of molecular biology 20081231
Nitro-oleic acid, a novel and irreversible inhibitor of xanthine oxidoreductase. The Journal of biological chemistry 20081226
Guanine radical reaction processes: a computational description of proton transfer in X-irradiated 9-ethylguanine single crystals. The journal of physical chemistry. B 20081225
In vitro reconstituted biotransformation of 4-fluorothreonine from fluoride ion: application of the fluorinase. Chemistry & biology 20081222
Hemodynamic variables and clinical features correlated with serum uric acid in patients with pulmonary arterial hypertension. Chinese medical journal 20081220
Plasmodium falciparum purine nucleoside phosphorylase is critical for viability of malaria parasites. The Journal of biological chemistry 20081219
Simulation study of noncovalent hybridization of carbon nanotubes by single-stranded DNA in water. The journal of physical chemistry. B 20081218
3' terminal nucleotides determine thermodynamic stabilities of mismatches at the ends of RNA helices. Biochemistry 20081216
Effect of the phosphate substrate on drug-inhibitor binding to human purine nucleoside phosphorylase. Archives of biochemistry and biophysics 20081215
Inhibition of siderophore biosynthesis by 2-triazole substituted analogues of 5'-O-[N-(salicyl)sulfamoyl]adenosine: antibacterial nucleosides effective against Mycobacterium tuberculosis. Journal of medicinal chemistry 20081211
An ab initio study of substituent effects on the excited states of purine derivatives. The journal of physical chemistry. A 20081204
Recent improvements in the development of A(2B) adenosine receptor agonists. Purinergic signalling 20081201
Purinergic-mediated Ca2+ influx in Dictyostelium discoideum. Cell calcium 20081201
Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection. Blood 20081201
D-ribose therapy in four Polish patients with adenylosuccinate lyase deficiency: absence of positive effect. Journal of inherited metabolic disease 20081201
Inflamed phenotype of the mesenteric microcirculation of melanocortin type 3 receptor-null mice after ischemia-reperfusion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081201
Pleiotropic effects of selective CDK inhibitors on human normal and cancer cells. Biochemical pharmacology 20081201
5'-p-Fluorosulfonyl benzoyl adenosine inhibits an ecto-ATP-diphosphohydrolase in the tegument surface of Taenia crassiceps cysticerci. Molecular and biochemical parasitology 20081201
UTP and ATP increase extracellular signal-regulated kinase 1/2 phosphorylation in bovine chromaffin cells through epidermal growth factor receptor transactivation. Purinergic signalling 20081201
Evidence for the possible involvement of the P2Y(6) receptor in Ca (2+) mobilization and insulin secretion in mouse pancreatic islets. Purinergic signalling 20081201
Repair of deaminated base damage by Schizosaccharomyces pombe thymine DNA glycosylase. DNA repair 20081201
Pharmacodynamics of mycophenolic acid in CD4+ cells: a single-dose study of IMPDH and purine nucleotide responses in healthy individuals. Therapeutic drug monitoring 20081201
A computational study of expanded heterocyclic nucleosides in DNA. Journal of biomolecular structure & dynamics 20081201
Failure to upregulate the adenosine2A receptor-epoxyeicosatrienoic acid pathway contributes to the development of hypertension in Dahl salt-sensitive rats. American journal of physiology. Renal physiology 20081201
Characterization of cytokinin and adenine transport in Arabidopsis cell cultures. Plant physiology 20081201
Effects of excitatory and inhibitory neurotransmission on motor patterns of human sigmoid colon in vitro. British journal of pharmacology 20081201
Regulation of enteric functions by adenosine: pathophysiological and pharmacological implications. Pharmacology & therapeutics 20081201
Lentivirus gene therapy for purine nucleoside phosphorylase deficiency. The journal of gene medicine 20081201
A genome-wide and metabolic analysis determined the adaptive response of Arabidopsis cells to folate depletion induced by methotrexate. Plant physiology 20081201
Folate status in various pathophysiological conditions. IUBMB life 20081201
Characterization of the DNA adducts induced by aristolochic acids in oligonucleotides by electrospray ionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20081201
Expression of 24,426 human alternative splicing events and predicted cis regulation in 48 tissues and cell lines. Nature genetics 20081201
Effectiveness of the fatty acid and sterol composition of seeds for the chemotaxonomy of Coffea subgenus Coffea. Phytochemistry 20081201
Interactions of mitoxantrone with duplex and triplex DNA studied by electrospray ionization mass spectrometry. Rapid communications in mass spectrometry : RCM 20081201
Hypoxanthine-guanine phosphoribosylotransferase deficiency--the spectrum of Polish mutations. Journal of inherited metabolic disease 20081201
Restoration of adenosine deaminase-deficient human thymocyte development in vitro by inhibition of deoxynucleoside kinases. Journal of immunology (Baltimore, Md. : 1950) 20081201
A novel nucleoside kinase from Burkholderia thailandensis: a member of the phosphofructokinase B-type family of enzymes. The FEBS journal 20081201
Tezosentan, a novel endothelin receptor antagonist, markedly reduces rat hepatic ischemia and reperfusion injury in three different models. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20081201
Effect on production of replacing dietary starch with sucrose in lactating dairy cows. Journal of dairy science 20081201
Arthrobacter oxydans as a biocatalyst for purine deamination. FEMS microbiology letters 20081201
Lactobacillus phylogenomics--towards a reclassification of the genus. International journal of systematic and evolutionary microbiology 20081201
A comparison of vitamin A and leucovorin for the prevention of methotrexate-induced micronuclei production in rat bone marrow. Clinics (Sao Paulo, Brazil) 20081201
Novel therapies for cutaneous T-cell lymphomas. Clinical lymphoma & myeloma 20081201
Human cytomegalovirus IE1 protein enhances herpes simplex virus type 1-induced syncytial formation in U373MG cells. Journal of Korean medical science 20081201
Decreasing mortality from non-Hodgkin lymphoma in Australia. Internal medicine journal 20081201
Induction of protective immunity against Burkholderia pseudomallei using attenuated mutants with defects in the intracellular life cycle. Transactions of the Royal Society of Tropical Medicine and Hygiene 20081201
The role for S-carboxymethylcysteine (carbocisteine) in the management of chronic obstructive pulmonary disease. International journal of chronic obstructive pulmonary disease 20081201
Febuxostat in the management of hyperuricemia and chronic gout: a review. Therapeutics and clinical risk management 20081201
Hormonal and biochemical parameters of metabolic syndrome in male patients with body weight excess and obesity. Bulletin of experimental biology and medicine 20081201
Activity-dependent release of adenosine: a critical re-evaluation of mechanism. Current neuropharmacology 20081201
Bis[5-oxo-4,5-dihydro-8H-2-azonia-4,8,9-trizabicyclo[4.3.0]nona-2,6,9(1)-triene] sulfate. Acta crystallographica. Section E, Structure reports online 20081201
Erythrocytic adenosine monophosphate as an alternative purine source in Plasmodium falciparum. The Journal of biological chemistry 20081121
Synthesis and degradation of nucleic acid components by formamide and iron sulfur minerals. Journal of the American Chemical Society 20081119
Effects of nucleobase metalation on frontier molecular orbitals: potential implications for pi-stacking interactions with tryptophan. Inorganic chemistry 20081117
Adenosine produced by neurons is metabolized to hypoxanthine by astrocytes. Journal of neuroscience research 20081115
Antiproliferative effects of AVN944, a novel inosine 5-monophosphate dehydrogenase inhibitor, in prostate cancer cells. International journal of cancer 20081115
Mapping the subunit interface of ribonucleotide reductase (RNR) using photo cross-linking. Bioorganic & medicinal chemistry letters 20081115
Immucillins in custom catalytic-site cavities. Bioorganic & medicinal chemistry letters 20081115
The GANC tetraloop: a novel motif in the group IIC intron structure. Journal of molecular biology 20081114
X-ray absorption spectroscopy of the nucleotide bases at the carbon, nitrogen, and oxygen K-edges. The journal of physical chemistry. B 20081106
The stereochemistry of trans-4-hydroxynonenal-derived exocyclic 1,N2-2'-deoxyguanosine adducts modulates formation of interstrand cross-links in the 5'-CpG-3' sequence. Biochemistry 20081104
Synthesis and pharmacological screening of derivatives of isoxazolo[4,5-d]pyrimidine. European journal of medicinal chemistry 20081101
Crohn's disease: factors associated with exposure to high levels of diagnostic radiation. Gut 20081101
Purine receptor antagonist modulates serology and affective behaviors in lupus-prone mice: evidence of autoimmune-induced pain? Brain, behavior, and immunity 20081101
Thermodynamics of single strand DNA base stacking. Biopolymers 20081101
Allopurinol, an inhibitor of purine catabolism, enhances susceptibility of tobacco to Tobacco mosaic virus. Virus research 20081101
Is ZMP the toxic metabolite in Lesch-Nyhan disease? Medical hypotheses 20081101
Structural biology of the purine biosynthetic pathway. Cellular and molecular life sciences : CMLS 20081101
Chemical substructures that enrich for biological activity. Bioinformatics (Oxford, England) 20081101
Structural studies of human purine nucleoside phosphorylase: towards a new specific empirical scoring function. Archives of biochemistry and biophysics 20081101
In situ measurements of aggregation and disaggregation of Cu(II) complex at liquid/liquid interface. Analytical chemistry 20081101
Effect of local sugar and base geometry on 13C and 15N magnetic shielding anisotropy in DNA nucleosides. Journal of biomolecular NMR 20081101
Inner-shell chemical shift of DNA/RNA bases and inheritance from their parent purine and pyrimidine. Journal of synchrotron radiation 20081101
Mutations in the SLC2A9 gene cause hyperuricosuria and hyperuricemia in the dog. PLoS genetics 20081101
A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus. PLoS pathogens 20081101
Xanthine oxidase inhibition with febuxostat attenuates systolic overload-induced left ventricular hypertrophy and dysfunction in mice. Journal of cardiac failure 20081101
Hypermutability of damaged single-strand DNA formed at double-strand breaks and uncapped telomeres in yeast Saccharomyces cerevisiae. PLoS genetics 20081101
A role for oxidized DNA precursors in Huntington's disease-like striatal neurodegeneration. PLoS genetics 20081101
Strong short-range correlations and dichotomic codon classes in coding DNA sequences. Physical review. E, Statistical, nonlinear, and soft matter physics 20081101
Formation of xanthine and the use of purine metabolites as a nitrogen source in Arabidopsis plants. Plant signaling & behavior 20081101
Hairy Cell Leukaemia in Oman: Four cases. Sultan Qaboos University medical journal 20081101
Identification of osteogenic purmorphamine derivatives. Molecules and cells 20081031
Adenosine A1 and A3 receptors protect astrocytes from hypoxic damage. European journal of pharmacology 20081031
Low-dose methotrexate therapy for intravenous immunoglobulin-resistant Kawasaki disease. Yonsei medical journal 20081031
The role of external and matrix pH in mitochondrial reactive oxygen species generation. The Journal of biological chemistry 20081024
Effect of the ribose versus 2'-deoxyribose residue on the metal ion-binding properties of purine nucleotides. Dalton transactions (Cambridge, England : 2003) 20081021
Photogeneration of 2-deoxyribonolactone in benzophenone-purine dyads. Formation of ketyl-C1' biradicals. Organic letters 20081016
7-Deaza-6-benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities. Biochemical pharmacology 20081015
TNAP, TrAP, ecto-purinergic signaling, and bone remodeling. Journal of cellular biochemistry 20081015
Fe(II)/alpha-ketoglutarate hydroxylases involved in nucleobase, nucleoside, nucleotide, and chromatin metabolism. Dalton transactions (Cambridge, England : 2003) 20081014
Identification and characterization of a new Leishmania major specific 3'nucleotidase/nuclease protein. Biochemical and biophysical research communications 20081010
Strand and nucleotide-dependent ATPase activity of gp16 of bacterial virus phi29 DNA packaging motor. Virology 20081010
Antinociceptive effects of intracerebroventricular administration of guanine-based purines in mice: evidences for the mechanism of action. Brain research 20081009
DNA with stable fluorinated dA and dG substitutes: syntheses, base pairing and 19F-NMR spectra of 7-fluoro-7-deaza-2'-deoxyadenosine and 7-fluoro-7-deaza-2'-deoxyguanosine. Organic & biomolecular chemistry 20081007
Overexpression, purification and characterization of functional calf purine nucleoside phosphorylase (PNP). Protein expression and purification 20081001
Dysregulation of purine nucleotide biosynthesis pathways modulates cisplatin cytotoxicity in Saccharomyces cerevisiae. Molecular pharmacology 20081001
Genetic evidence for the essential role of PfNT1 in the transport and utilization of xanthine, guanine, guanosine and adenine by Plasmodium falciparum. Molecular and biochemical parasitology 20081001
Characteristics and prediction of RNA editing sites in transcripts of the Moss Takakia lepidozioides chloroplast. DNA research : an international journal for rapid publication of reports on genes and genomes 20081001
Identification of urinary modified nucleosides and ribosylated metabolites in humans via combined ESI-FTICR MS and ESI-IT MS analysis. Journal of the American Society for Mass Spectrometry 20081001
Construction of signature-tagged mutant library in Mesorhizobium loti as a powerful tool for functional genomics. DNA research : an international journal for rapid publication of reports on genes and genomes 20081001
In vitro polydeoxyribonucleotide effects on human pre-adipocytes. Cell proliferation 20081001
AMP hydrolysis in soluble and microsomal rat cardiac cell fractions: kinetic characterization and molecular identification of 5'-nucleotidase. Bioscience reports 20081001
Interaction of the DNA bases and their mononucleotides with pyridine-2-carbaldehyde thiosemicarbazonecopper(II) complexes. Structure of the cytosine derivative. Journal of inorganic biochemistry 20081001
Ascendancy of weekly low-dose methotrexate in usual care of rheumatoid arthritis from 1980 to 2004 at two sites in Finland and the United States. Rheumatology (Oxford, England) 20081001
Dynamic regulation of uncoupling protein 2 content in INS-1E insulinoma cells. Biochimica et biophysica acta 20081001
Molecular basis of halorespiration control by CprK, a CRP-FNR type transcriptional regulator. Molecular microbiology 20081001
Protein cooperation: from neurons to networks. Progress in neurobiology 20081001
Kinase array design, back to front: biaryl amides. Bioorganic & medicinal chemistry letters 20081001
Hairy cell leukemia: current concepts. Cancer investigation 20081001
Development of drug resistance in Trypanosoma brucei rhodesiense and Trypanosoma brucei gambiense. Treatment of human African trypanosomiasis with natural products (Review). International journal of molecular medicine 20081001
The relative merit of ruminal undegradable protein from soybean meal or soluble fiber from beet pulp to improve nitrogen utilization in dairy cows. Journal of dairy science 20081001
[Recent therapeutic progress in non-Hodgkin lymphoma: focusing on diffuse large B-cell lymphoma and follicular lymphoma]. [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001
SLC2A9 is a high-capacity urate transporter in humans. PLoS medicine 20081001
FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells. Molecular cancer therapeutics 20081001
Effects of isobutyrate on rumen fermentation, urinary excretion of purine derivatives and digestibility in steers. Archives of animal nutrition 20081001
Extracellular ATP-induced NO production and its dependence on membrane Ca2+ flux in Salvia miltiorrhiza hairy roots. Journal of experimental botany 20081001
7-Dimethyl-amino-2-phenyl-1,2,4-triazolo[1,5-a][1,3,5]triazin-5-amine methanol solvate. Acta crystallographica. Section E, Structure reports online 20081001
A beta-fluoroamine inhibitor of purine nucleoside phosphorylase. Journal of medicinal chemistry 20080925
Mutations of RNA polymerase II activate key genes of the nucleoside triphosphate biosynthetic pathways. The EMBO journal 20080917
Uric acid in Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20080915
MetaRoute: fast search for relevant metabolic routes for interactive network navigation and visualization. Bioinformatics (Oxford, England) 20080915
Formation of DNA-protein cross-links between gamma-hydroxypropanodeoxyguanosine and EcoRI. Chemical research in toxicology 20080915
Structure of the 1,N2-ethenodeoxyguanosine adduct opposite cytosine in duplex DNA: Hoogsteen base pairing at pH 5.2. Chemical research in toxicology 20080915
P-Glycoprotein-mediated resistance to Hsp90-directed therapy is eclipsed by the heat shock response. Cancer research 20080915
Structures of substrate- and inhibitor-bound adenosine deaminase from a human malaria parasite show a dramatic conformational change and shed light on drug selectivity. Journal of molecular biology 20080912
Functional chimeras of the phosphodiesterase 5 and 10 tandem GAF domains. The Journal of biological chemistry 20080912
New phenolic components and chromatographic profiles of green and fermented teas. Journal of agricultural and food chemistry 20080910
Status epilepticus induces a particular microglial activation state characterized by enhanced purinergic signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience 20080910
A conformationally mobile cysteine residue (Cys-561) modulates Na+ and H+ activation of human CNT3. The Journal of biological chemistry 20080905
Interconversion of the cis-5R,6S- and trans-5R,6R-thymine glycol lesions in duplex DNA. Journal of the American Chemical Society 20080903
Molecular pathways involved in the synergistic interaction of the PKC beta inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells. British journal of cancer 20080902
Presence of epidermal allantoin further supports oxidative stress in vitiligo. Experimental dermatology 20080901
Purinergic receptors and synaptic transmission in enteric neurons. Purinergic signalling 20080901
Purinergic mechanisms in the control of gastrointestinal motility. Purinergic signalling 20080901
Pancreatic cancer: from molecular pathogenesis to targeted therapy. Cancer metastasis reviews 20080901
Mutation of Trp29 of human equilibrative nucleoside transporter 1 alters affinity for coronary vasodilator drugs and nucleoside selectivity. The Biochemical journal 20080901
Accumulation of M1dG DNA adducts after chronic exposure to PCBs, but not from acute exposure to polychlorinated aromatic hydrocarbons. Free radical biology & medicine 20080901
The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes. The Journal of endocrinology 20080901
Extracellular ATP and cancer: an overview with special reference to P2 purinergic receptors. Pathology oncology research : POR 20080901
DNA binding by Ru(II)-bis(bipyridine)-pteridinyl complexes. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20080901
Genes and networks expressed in perioperative omental adipose tissue are correlated with weight loss from Roux-en-Y gastric bypass. International journal of obesity (2005) 20080901
Novel N9-arenethenyl purines as potent dual Src/Abl tyrosine kinase inhibitors. Bioorganic & medicinal chemistry letters 20080901
Design and SAR of new substituted purines bearing aryl groups at N9 position as HIV-1 Tat-TAR interaction inhibitors. Bioorganic & medicinal chemistry 20080901
The use of 10-23 DNAzyme to selectively destroy the allele of mRNA with a unique purine-pyrimidine dinucleotide. Oligonucleotides 20080901
[Do folates have an impact on fertility?]. Gynecologie, obstetrique & fertilite 20080901
Pentostatin in chronic lymphocytic leukemia. Expert opinion on drug metabolism & toxicology 20080901
UVC induced oxidation of chloropurines: excited singlet and triplet pathways for the photoreaction. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20080901
Lactobacillus plantarum response to inorganic carbon concentrations: PyrR2-dependent and -independent transcription regulation of genes involved in arginine and nucleotide metabolism. Microbiology (Reading, England) 20080901
Sustained contraction and endothelial dysfunction induced by reactive oxygen species in porcine coronary artery. Biological & pharmaceutical bulletin 20080901
Attenuated Plasmodium yoelii lacking purine nucleoside phosphorylase confer protective immunity. Nature medicine 20080901
Association of a common nonsynonymous variant in GLUT9 with serum uric acid levels in old order amish. Arthritis and rheumatism 20080901
The effect of feeding dried distillers grains plus solubles on milk production and excretion of urinary purine derivatives. Journal of dairy science 20080901
Rumen digestion and nutritional efficiency of dairy heifers limit-fed a high forage ration to four levels of dry matter intake. Journal of dairy science 20080901
Variable expression of HPRT deficiency in 5 members of a family with the same mutation. Archives of neurology 20080901
Hydrophilic interaction chromatography in nonaqueous elution mode for separation of hydrophilic analytes on silica-based packings with noncharged polar bondings. Journal of separation science 20080901
The genome of Borrelia recurrentis, the agent of deadly louse-borne relapsing fever, is a degraded subset of tick-borne Borrelia duttonii. PLoS genetics 20080901
[Monitoring of immunosuppressant drugs]. Therapeutische Umschau. Revue therapeutique 20080901
FtsK-dependent dimer resolution on multiple chromosomes in the pathogen Vibrio cholerae. PLoS genetics 20080901
Needles in the EST haystack: large-scale identification and analysis of excretory-secretory (ES) proteins in parasitic nematodes using expressed sequence tags (ESTs). PLoS neglected tropical diseases 20080901
Capturing hammerhead ribozyme structures in action by modulating general base catalysis. PLoS biology 20080901
Infliximab in ulcerative colitis. Biologics : targets & therapy 20080901
Tipifarnib in the treatment of newly diagnosed acute myelogenous leukemia. Biologics : targets & therapy 20080901
Photophysical characters of rationally designed hetero-ring-expanded guanine analogues and effect of cytosine pairing. The journal of physical chemistry. B 20080828
Rearrangement of the (6S,8R,11S) and (6R,8S,11R) exocyclic 1,N2-deoxyguanosine adducts of trans-4-hydroxynonenal to N2-deoxyguanosine cyclic hemiacetal adducts when placed complementary to cytosine in duplex DNA. Journal of the American Chemical Society 20080820
A kinetic alignment of orthologous inosine-5'-monophosphate dehydrogenases. Biochemistry 20080819
The purine machine scores a base hit. ACS chemical biology 20080815
Pathway engineered enzymatic de novo purine nucleotide synthesis. ACS chemical biology 20080815
Photosensitized breakage and damage of DNA by CdSe-ZnS quantum dots. The journal of physical chemistry. B 20080814
Binding to DNA purine base and structure-activity relationship of a series of structurally related Ru(II) antitumor complexes: a theoretical study. The journal of physical chemistry. B 20080814
A flexible loop as a functional element in the catalytic mechanism of nucleoside hydrolase from Trypanosoma vivax. The Journal of biological chemistry 20080808
Formation of purine-purine mispairs by Sulfolobus solfataricus DNA polymerase IV. Biochemistry 20080805
Regiospecific microwave-assisted synthesis and cytotoxic activity against human breast cancer cells of (RS)-6-substituted-7- or 9-(2,3-dihydro-5H-1,4-benzodioxepin-3-yl)-7H- or -9H-purines. European journal of medicinal chemistry 20080801
Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H. Leukemia research 20080801
Knockdown of cytosolic 5'-nucleotidase II (cN-II) reveals that its activity is essential for survival in astrocytoma cells. Biochimica et biophysica acta 20080801
Molecular characterization, heterologous expression and kinetic analysis of recombinant Plasmodium falciparum thymidylate kinase. Journal of biochemistry 20080801
Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI. Diabetes care 20080801
Superstructural self-assembly of the G-quadruplex structure formed by the homopurine strand in a DNA tract of human telomerase gene promoter. Biophysical chemistry 20080801
Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX. Rheumatology (Oxford, England) 20080801
Human rheumatoid synoviocytes express functional P2X7 receptors. Journal of molecular medicine (Berlin, Germany) 20080801
Purine salvage pathways in the intraerythrocytic malaria parasite Plasmodium falciparum. Eukaryotic cell 20080801
p42/44 MAPK is an essential effector for purine nucleoside-mediated neuroprotection of hypoxic PC12 cells and primary cerebellar granule neurons. Molecular and cellular neurosciences 20080801
Fine targeting of purine salvage in Cryptosporidium parasites. Trends in parasitology 20080801
Molecular and functional mapping of regional differences in P2Y receptor expression in the rat lens. Experimental eye research 20080801
Release of ATP and glutamate in the nucleus tractus solitarii mediate pulmonary stretch receptor (Breuer-Hering) reflex pathway. The Journal of physiology 20080801
Structures of Arthrobacter globiformis urate oxidase-ligand complexes. Acta crystallographica. Section D, Biological crystallography 20080801
Cadmium, cobalt and lead cause stress response, cell cycle deregulation and increased steroid as well as xenobiotic metabolism in primary normal human bronchial epithelial cells which is coordinated by at least nine transcription factors. Archives of toxicology 20080801
Acadesine, an adenosine-regulating agent with the potential for widespread indications. Expert opinion on pharmacotherapy 20080801
Structure of the Brachydanio rerio Polo-like kinase 1 (Plk1) catalytic domain in complex with an extended inhibitor targeting the adaptive pocket of the enzyme. Acta crystallographica. Section F, Structural biology and crystallization communications 20080801
Delayed and accelerated aging share common longevity assurance mechanisms. PLoS genetics 20080801
The interaction of gabapentin and N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) on mechanical allodynia in rats with a spinal nerve ligation. Journal of Korean medical science 20080801
Proteomic analysis of recombinant Saccharomyces cerevisiae upon iron deficiency induced via human H-ferritin production. Journal of microbiology and biotechnology 20080801
Novel agents in chronic lymphocytic leukemia: efficacy and tolerability of new therapies. Clinical lymphoma & myeloma 20080801
Present and prospective clinical therapeutic regimens for Alzheimer's disease. Neuropsychiatric disease and treatment 20080801
Bendamustine HCL for the treatment of relapsed indolent non-Hodgkin's lymphoma. Therapeutics and clinical risk management 20080801
Remarkable metal counterion effect on the internucleotide J-couplings and chemical shifts of the N-H...N hydrogen bonds in the W-C base pairs. The journal of physical chemistry. B 20080731
Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation. Biochemistry 20080729
Altered order of substrate binding by DNA polymerase X from African Swine Fever virus. Biochemistry 20080729
Regulation of a eukaryotic gene by GTP-dependent start site selection and transcription attenuation. Molecular cell 20080725
Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase. Journal of medicinal chemistry 20080724
Synthesis and reactivity of the aquation product of the antitumor complex trans-[Ru(III)Cl4(indazole)2]-. Inorganic chemistry 20080721
Redox state of quinone affects sensitivity of Acanthamoeba castellanii mitochondrial uncoupling protein to purine nucleotides. The Biochemical journal 20080715
High membrane potential promotes alkenal-induced mitochondrial uncoupling and influences adenine nucleotide translocase conformation. The Biochemical journal 20080715
Levodopa therapy in a Lesch-Nyhan disease patient: pathological, biochemical, neuroimaging, and therapeutic remarks. Movement disorders : official journal of the Movement Disorder Society 20080715
N-Arylmethyl substituted iminoribitol derivatives as inhibitors of a purine specific nucleoside hydrolase. Bioorganic & medicinal chemistry 20080715
Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry. Bioorganic & medicinal chemistry letters 20080715
Synthesis of substituted 6-cyclopropylpurine bases and nucleosides by cross-coupling reactions or cyclopropanations. Organic & biomolecular chemistry 20080707
Modified uridines with C5-methylene substituents at the first position of the tRNA anticodon stabilize U.G wobble pairing during decoding. The Journal of biological chemistry 20080704
The fate of C5' radicals of purine nucleosides under oxidative conditions. Journal of the American Chemical Society 20080702
The depletion of cellular ATP by AG2034 mediates cell death or cytostasis in a hypoxanthine-dependent manner in human prostate cancer cells. Cancer chemotherapy and pharmacology 20080701
Influence of the metabolic properties of human cells on the kinetic of formation of the major benzo[a]pyrene DNA adducts. Journal of applied toxicology : JAT 20080701
Gout in the UK and Germany: prevalence, comorbidities and management in general practice 2000-2005. Annals of the rheumatic diseases 20080701
Decrease in factor V activity: a new adverse effect of purine analogs in inflammatory bowel diseases? Inflammatory bowel diseases 20080701
Therapeutic benefit of pentostatin in severe IL-10-/- colitis. Inflammatory bowel diseases 20080701
Influence of direct-fed fibrolytic enzymes on diet digestibility and ruminal activity in sheep fed a grass hay-based diet. Journal of animal science 20080701
Effect of mode of birth on purine and malondialdehyde in umbilical arterial plasma in normal term newborns. Journal of perinatology : official journal of the California Perinatal Association 20080701
Adenosine induces hemeoxygenase-1 expression in microglia through the activation of phosphatidylinositol 3-kinase and nuclear factor E2-related factor 2. Glia 20080701
Synergistic effects of the purine analog sulfinosine and curcumin on the multidrug resistant human non-small cell lung carcinoma cell line (NCI-H460/R). Cancer biology & therapy 20080701
Synergistic antitumor efficacy of suicide/ePNP gene and 6-methylpurine 2'-deoxyriboside via Salmonella against murine tumors. Cancer gene therapy 20080701
Characterization of the acute temporal changes in excisional murine cutaneous wound inflammation by screening of the wound-edge transcriptome. Physiological genomics 20080701
Effect of a new non-cleavable substrate analog on wild-type and serine mutants in the signature sequence of adenylosuccinate lyase of Bacillus subtilis and Homo sapiens. Protein science : a publication of the Protein Society 20080701
Genotoxic and cytotoxic potential of titanium dioxide (TiO2) nanoparticles on fish cells in vitro. Ecotoxicology (London, England) 20080701
Mechanistic insights into the Michael addition of deoxyguanosine to catechol estrogen-3,4-quinones. Chemical research in toxicology 20080701
3'-Intercalation of a N2-dG 1R-trans-anti-benzo[c]phenanthrene DNA adduct in an iterated (CG)3 repeat. Chemical research in toxicology 20080701
Altered expression of methylenetetrahydrofolate reductase modifies response to methotrexate in mice. Pharmacogenetics and genomics 20080701
Chemical and genetic validation of dihydrofolate reductase-thymidylate synthase as a drug target in African trypanosomes. Molecular microbiology 20080701
Influence of carbohydrate source on ruminal fermentation characteristics, performance, and microbial protein synthesis in dairy cows. Journal of dairy science 20080701
A general method for phasing novel complex RNA crystal structures without heavy-atom derivatives. Acta crystallographica. Section D, Biological crystallography 20080701
Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP. Acta crystallographica. Section D, Biological crystallography 20080701
Alemtuzumab for B-cell chronic lymphocytic leukemia. Expert review of anticancer therapy 20080701
Purine and pyrimidine derivatives from the South China Sea gorgonian Subergorgia suberosa. Chemical & pharmaceutical bulletin 20080701
Purinergic signalling and disorders of the central nervous system. Nature reviews. Drug discovery 20080701
Induction of nucleoside phosphorylase in Enterobacter aerogenes and enzymatic synthesis of adenine arabinoside. Journal of Zhejiang University. Science. B 20080701
Differentiation and gene flow among European populations of Leishmania infantum MON-1. PLoS neglected tropical diseases 20080701
Arabidopsis 10-formyl tetrahydrofolate deformylases are essential for photorespiration. The Plant cell 20080701
Mathematical modeling of folate metabolism: predicted effects of genetic polymorphisms on mechanisms and biomarkers relevant to carcinogenesis. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080701
Brevetoxin forms covalent DNA adducts in rat lung following intratracheal exposure. Environmental health perspectives 20080701
SLC28 genes and concentrative nucleoside transporter (CNT) proteins. Xenobiotica; the fate of foreign compounds in biological systems 20080701
Human equilibrative nucleoside transporter (ENT) family of nucleoside and nucleobase transporter proteins. Xenobiotica; the fate of foreign compounds in biological systems 20080701
Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents. Archives of pharmacal research 20080701
Bendamustine in chronic lymphocytic leukemia and refractory lymphoma. Seminars in hematology 20080701
Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications. Journal of molecular biology 20080627
Liquid crystalline phase of G-tetrad DNA for NMR study of detergent-solubilized proteins. Journal of the American Chemical Society 20080618
Pleuromutilin derivatives having a purine ring. Part 1: new compounds with promising antibacterial activity against resistant Gram-positive pathogens. Bioorganic & medicinal chemistry letters 20080615
HPLC assay with UV detection for determination of RBC purine nucleotide concentrations and application for biomarker study in vivo. Journal of pharmaceutical and biomedical analysis 20080609
Targeting gene therapy for hepatocarcinoma cells with the E. coli purine nucleoside phosphorylase suicide gene system directed by a chimeric alpha-fetoprotein promoter. Cancer letters 20080608
Separation of purine and pyrimidine bases by ion chromatography with direct conductivity detection. Journal of chromatography. A 20080606
The dynamic structural basis of differential enhancement of conformational stability by 5'- and 3'-dangling ends in RNA. Biochemistry 20080603
A single center experience of methotrexate in the treatment of Crohn's disease and ulcerative colitis: a case for subcutaneous administration. Journal of gastroenterology and hepatology 20080601
Mapping two genes in the purine metabolism pathway of soybean. DNA sequence : the journal of DNA sequencing and mapping 20080601
Extracellular ATP is a pro-angiogenic factor for pulmonary artery vasa vasorum endothelial cells. Angiogenesis 20080601
An unconditioned bone marrow transplantation in a child with purine nucleoside phosphorylase deficiency and its unique complication. Pediatric transplantation 20080601
HIF-1 alpha is an essential effector for purine nucleoside-mediated neuroprotection against hypoxia in PC12 cells and primary cerebellar granule neurons. Journal of neurochemistry 20080601
Mitochondrial respiratory pathways modulate nitrate sensing and nitrogen-dependent regulation of plant architecture in Nicotiana sylvestris. The Plant journal : for cell and molecular biology 20080601
Prolymphocytic leukaemia of B- and T-cell subtype: a state-of-the-art paper. European journal of haematology 20080601
The paradoxical relationship between serum uric acid and cardiovascular disease. Clinica chimica acta; international journal of clinical chemistry 20080601
A TSC22-like motif defines a novel antiapoptotic protein family. FEMS yeast research 20080601
The complete nucleotide sequence of the type 5 Helicoverpa armigera cytoplasmic polyhedrosis virus genome. Virus genes 20080601
A case of serendipity*. Purinergic signalling 20080601
Oxygen-glucose deprivation induces ATP release via maxi-anion channels in astrocytes. Purinergic signalling 20080601
Purinergic signalling in the subretinal space: a role in the communication between the retina and the RPE. Purinergic signalling 20080601
Structural complexes of human adenine phosphoribosyltransferase reveal novel features of the APRT catalytic mechanism. Journal of biomolecular structure & dynamics 20080601
Effect of Veillonella parvula on the antimicrobial resistance and gene expression of Streptococcus mutans grown in a dual-species biofilm. Oral microbiology and immunology 20080601
Giardia lamblia: biochemical characterization of an ecto-ATPase activity. Experimental parasitology 20080601
Serum urate as a predictor of clinical and radiographic progression in Parkinson disease. Archives of neurology 20080601
A purine-selective nucleobase/nucleoside transporter in PK15NTD cells. American journal of physiology. Regulatory, integrative and comparative physiology 20080601
Characterization of nucleoside triphosphate diphosphohydrolase activity in Trichomonas gallinae and the influence of penicillin and streptomycin in extracellular nucleotide hydrolysis. FEMS microbiology letters 20080601
Characterization of Aquifex aeolicus 4-diphosphocytidyl-2C-methyl-d-erythritol kinase - ligand recognition in a template for antimicrobial drug discovery. The FEBS journal 20080601
Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line. American journal of physiology. Heart and circulatory physiology 20080601
Suicide gene/prodrug therapy using salmonella-mediated delivery of Escherichia coli purine nucleoside phosphorylase gene and 6-methoxypurine 2'-deoxyriboside in murine mammary carcinoma 4T1 model. Cancer science 20080601
Nucleoside composition of Heloderma venoms. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080601
Co-regulation of yeast purine and phosphate pathways in response to adenylic nucleotide variations. Molecular microbiology 20080601
Oxidative stress impairs the repair of oxidative DNA base modifications in human skin fibroblasts and melanoma cells. DNA repair 20080601
Recognition and incision of Cr(III) ligand-conjugated DNA adducts by the nucleotide excision repair proteins UvrABC: importance of the Cr(III)-purine moiety in the enzymatic reaction. Chemical research in toxicology 20080601
Localization and nucleotide specificity of Blastocystis succinyl-CoA synthetase. Molecular microbiology 20080601
Monitoring in vivo metabolism and elimination of the endogenous DNA adduct, M1dG {3-(2-deoxy-beta-D-erythro-pentofuranosyl)pyrimido[1,2-alpha]purin-10(3H)-one}, by accelerator mass spectrometry. Chemical research in toxicology 20080601
Identification and characterization of a novel adenine phosphoribosyltransferase gene (ZmAPT2) from maize (Zea mays L.). DNA sequence : the journal of DNA sequencing and mapping 20080601
Imaging of cell proliferation: status and prospects. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20080601
Downregulation of the Escherichia coli guaB promoter by FIS. Microbiology (Reading, England) 20080601
CSMET: comparative genomic motif detection via multi-resolution phylogenetic shadowing. PLoS computational biology 20080601
Novel purine nucleoside analogues for hematological malignancies. Recent patents on anti-cancer drug discovery 20080601
[Ultrastructural analysis of 5' nucleotides distribution in acute myeloid leukemia subtypes]. Zhongguo shi yan xue ye xue za zhi 20080601
The 1.25 A resolution structure of phosphoribosyl-ATP pyrophosphohydrolase from Mycobacterium tuberculosis. Acta crystallographica. Section D, Biological crystallography 20080601
FDA drug approval summary: nelarabine (Arranon) for the treatment of T-cell lymphoblastic leukemia/lymphoma. The oncologist 20080601
Concepts of neural nitric oxide-mediated transmission. The European journal of neuroscience 20080601
PP07: new approaches, new knowledge, new challenges in human purine and pyrimidine metabolism. Nucleosides, nucleotides & nucleic acids 20080601
The diagnosis of HPRT deficiency in the 21st century. Nucleosides, nucleotides & nucleic acids 20080601
Effects of allopurinol on beer-induced increases in plasma concentrations of purine bases and uridine. Nucleosides, nucleotides & nucleic acids 20080601
Antioxidant status and purine bases in carotid artery plaque. Nucleosides, nucleotides & nucleic acids 20080601
Purine contents of soybean-derived foods and selected Japanese vegetables and mushrooms. Nucleosides, nucleotides & nucleic acids 20080601
Effect of acarbose on the increased plasma concentration of uric acid induced by sucrose ingestion. Nucleosides, nucleotides & nucleic acids 20080601
Fludarabine induces differential expression of proteins in human leukemia and lymphoma cells. Nucleosides, nucleotides & nucleic acids 20080601
Unusual presentation of Kelley-Seegmiller syndrome. Nucleosides, nucleotides & nucleic acids 20080601
Neurotrophic effects of extracellular guanosine. Nucleosides, nucleotides & nucleic acids 20080601
Molecular mechanisms of mitochondrial DNA depletion diseases caused by deficiencies in enzymes in purine and pyrimidine metabolism. Nucleosides, nucleotides & nucleic acids 20080601
Inhibition of deoxynucleoside kinases in human thymocytes prevents dATP accumulation and induction of apoptosis. Nucleosides, nucleotides & nucleic acids 20080601
Modulation of AMP deaminase in rat hearts subjected to ischemia and reperfusion by purine riboside. Nucleosides, nucleotides & nucleic acids 20080601
Interactions of beta- and hydroxypropyl-beta-cyclodextrin with some purine alkaloids: thermodynamic study. Current drug discovery technologies 20080601
Pemetrexed as second-line therapy for advanced non-small-cell lung cancer (NSCLC). Therapeutics and clinical risk management 20080601
Treatment strategies in mucous membrane pemphigoid. Therapeutics and clinical risk management 20080601
PP07. Proceedings of the 12th International Symposium on Purine and Pyrimidine Metabolism in Man, Chicago, Illinois, USA, June 2007. Nucleosides, nucleotides & nucleic acids 20080601
Electrochemical Investigation of oligonucleotide-DNA hybridization on poly(4-methoxyphenethylamine). International journal of molecular sciences 20080601
Key labeling technologies to tackle sizeable problems in RNA structural biology. International journal of molecular sciences 20080601
Mycophenolate mofetil in the treatment of lupus nephritis. Biologics : targets & therapy 20080601
Comparative evaluation of some flavonoids and tocopherol acetate against the systemic toxicity induced by sulphur mustard. Indian journal of pharmacology 20080601
Characterization of intestinal absorption of mizoribine mediated by concentrative nucleoside transporters in rats. European journal of pharmacology 20080531
Glutamatergic and purinergic mechanisms on respiratory modulation in the caudal NTS of awake rats. Respiratory physiology & neurobiology 20080531
Prediction of translation initiation sites in human mRNA sequences with AUG start codon in weak Kozak context: A neural network approach. Biochemical and biophysical research communications 20080516
Cysteine-scanning analysis of putative helix XII in the YgfO xanthine permease: ILE-432 and ASN-430 are important. The Journal of biological chemistry 20080516
Differential effects of chemotherapeutic drugs versus the MDM-2 antagonist nutlin-3 on cell cycle progression and induction of apoptosis in SKW6.4 lymphoblastoid B-cells. Journal of cellular biochemistry 20080515
Remote mutations and active site dynamics correlate with catalytic properties of purine nucleoside phosphorylase. Biophysical journal 20080515
Energization-dependent endogenous activation of proton conductance in skeletal muscle mitochondria. The Biochemical journal 20080515
Human in vivo research on the vascular effects of adenosine. European journal of pharmacology 20080513
Low expression of gamma-glutamyl hydrolase mRNA in primary colorectal cancer with the CpG island methylator phenotype. British journal of cancer 20080506
Investigation of DNA-protein cross-link formation between lysozyme and oxanine by mass spectrometry. Chembiochem : a European journal of chemical biology 20080505
Structural basis for substrate promiscuity of dCK. Journal of molecular biology 20080502
IMPDH1 gene polymorphisms and association with acute rejection in renal transplant patients. Clinical pharmacology and therapeutics 20080501
Adenosine: trigger and mediator of cardioprotection. Basic research in cardiology 20080501
The nadA gene of Aspergillus nidulans, encoding adenine deaminase, is subject to a unique regulatory pattern. Fungal genetics and biology : FG & B 20080501
Reactive oxygen species are the major antibacterials against Salmonella Typhimurium purine auxotrophs in the phagosome of RAW 264.7 cells. Cellular microbiology 20080501
Controversies in the front-line management of chronic lymphocytic leukemia. Leukemia research 20080501
The separation of antagonist from agonist effects of trisubstituted purines on CaV2.2 (N-type) channels. Journal of neurochemistry 20080501
A CD study of uncoupling protein-1 and its transmembrane and matrix-loop domains. The Biochemical journal 20080501
Extracellular purines are biomarkers of neutrophilic airway inflammation. The European respiratory journal 20080501
A critical role for ureides in dark and senescence-induced purine remobilization is unmasked in the Atxdh1 Arabidopsis mutant. The Plant journal : for cell and molecular biology 20080501
Purine nucleoside phosphorylase from Pseudoalteromonas sp. Bsi590: molecular cloning, gene expression and characterization of the recombinant protein. Extremophiles : life under extreme conditions 20080501
Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade. Biochimica et biophysica acta 20080501
Chronic dietary L-arginine down-regulates adenosine receptor and nitric oxide synthase expression in rat heart. Basic & clinical pharmacology & toxicology 20080501
Xanthine oxidoreductase in respiratory and cardiovascular disorders. American journal of physiology. Lung cellular and molecular physiology 20080501
An important role of G638 in the cis-cleavage reaction of the Neurospora VS ribozyme revealed by a novel nucleotide analog incorporation method. RNA (New York, N.Y.) 20080501
A widespread riboswitch candidate that controls bacterial genes involved in molybdenum cofactor and tungsten cofactor metabolism. Molecular microbiology 20080501
Effect of trimetazidine on xanthine oxidoreductase expression in rat kidney with ischemia--reperfusion injury. Archives of medical research 20080501
Molecular modeling and dynamics simulations of PNP from Streptococcus agalactiae. Bioorganic & medicinal chemistry 20080501
The Aspergillus nidulans FcyB cytosine-purine scavenger is highly expressed during germination and in reproductive compartments and is downregulated by endocytosis. Molecular microbiology 20080501
Oxidative amination of cuprated pyrimidine and purine derivatives. Organic letters 20080501
Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists. Bioorganic & medicinal chemistry letters 20080501
Profound hypogammaglobulinemia 7 years after treatment for indolent lymphoma. Cancer investigation 20080501
A detailed view on the constituents of EPs 7630. Planta medica 20080501
Acid phosphatases from the liver of Labeo rohita: purification and characterization. Biological & pharmaceutical bulletin 20080501
Life without RNase P. Nature 20080501
Complete genome sequence of the complex carbohydrate-degrading marine bacterium, Saccharophagus degradans strain 2-40 T. PLoS genetics 20080501
The electron affinities of deprotonated adenine, guanine, cytosine, uracil, and thymine. Nucleosides, nucleotides & nucleic acids 20080501
Genome analysis of food grade lactic Acid-producing bacteria: from basics to applications. Current genomics 20080501
6-(2-Methoxy-benzyl-amino)purine. Acta crystallographica. Section E, Structure reports online 20080501
The role of NMDA receptor antagonists in nicotine tolerance, sensitization, and physical dependence: a preclinical review. Yonsei medical journal 20080430
Computational and experimental evidence for the structural preference of phenolic C-8 purine adducts. The journal of physical chemistry. A 20080424
2'-Deoxyimmunosine: stereoselective synthesis, base pairing and duplex stability of oligonucleotides containing 8-oxo-7-thiaguanine. Organic & biomolecular chemistry 20080421
Therapeutic effects of combined treatment with ribavirin and tiazofurin on experimental autoimmune encephalomyelitis development: clinical and histopathological evaluation. Journal of the neurological sciences 20080415
A comprehensive model of purine uptake by the malaria parasite Plasmodium falciparum: identification of four purine transport activities in intraerythrocytic parasites. The Biochemical journal 20080415
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients. Blood 20080415
Design and synthesis of nitrate esters of aromatic heterocyclic compounds as pharmacological preconditioning agents. Bioorganic & medicinal chemistry 20080415
Structure-activity relationship for adenosine kinase from Mycobacterium tuberculosis II. Modifications to the ribofuranosyl moiety. Biochemical pharmacology 20080415
Structural basis for substrate specificity in group I nucleoside hydrolases. Biochemistry 20080415
Water-soluble pleuromutilin derivative with excellent in vitro and in vivo antibacterial activity against gram-positive pathogens. Journal of medicinal chemistry 20080410
Stereospecific synthesis of sugar-1-phosphates and their conversion to sugar nucleotides. Carbohydrate research 20080407
Mechanisms of base selection by the Escherichia coli mispaired uracil glycosylase. The Journal of biological chemistry 20080404
Reversible compartmentalization of de novo purine biosynthetic complexes in living cells. Science (New York, N.Y.) 20080404
Hydroxyl radicals (*OH) are associated with titanium dioxide (TiO(2)) nanoparticle-induced cytotoxicity and oxidative DNA damage in fish cells. Mutation research 20080402
A proteomic view of Candida albicans yeast cell metabolism in exponential and stationary growth phases. International journal of medical microbiology : IJMM 20080401
Effect of spermine conjugation on the interaction of acridine with alternating purine-pyrimidine oligodeoxyribonucleotides studied by CD, fluorescence and absorption spectroscopies. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401
Characterization and kinetics of the major purine transporters in Aspergillus fumigatus. Fungal genetics and biology : FG & B 20080401
Higher biomass accumulation by increasing phosphoribosylpyrophosphate synthetase activity in Arabidopsis thaliana and Nicotiana tabacum. Plant biotechnology journal 20080401
Adenosine, through the A1 receptor, inhibits vesicular MHC class I cross-presentation by resting DC. Molecular immunology 20080401
Up4A stimulates endothelium-independent contraction of isolated rat pulmonary artery. American journal of physiology. Lung cellular and molecular physiology 20080401
Assessment of genotoxicity in rats treated with the antidiabetic agent, pioglitazone. Environmental and molecular mutagenesis 20080401
Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP. Molecular pharmacology 20080401
Differential expression of glycosomal and mitochondrial proteins in the two major life-cycle stages of Trypanosoma brucei. Molecular and biochemical parasitology 20080401
The peroxisome: still a mysterious organelle. Histochemistry and cell biology 20080401
Excision of the nifD element in the heterocystous cyanobacteria. Archives of microbiology 20080401
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorganic & medicinal chemistry 20080401
Purine alkaloids from the South China Sea gorgonian Subergorgia suberosa. Journal of natural products 20080401
Comparative molecular biological analysis of membrane transport genes in organisms. Plant molecular biology 20080401
A continuous assay of acetate kinase activity: measurement of inorganic phosphate release generated by hydroxylaminolysis of acetyl phosphate. Bioorganic chemistry 20080401
Mechanisms of leukocyte migration across the blood-retina barrier. Seminars in immunopathology 20080401
The CBS subdomain of inosine 5'-monophosphate dehydrogenase regulates purine nucleotide turnover. Molecular microbiology 20080401
Variation of serum uric acid levels in multiple sclerosis during relapses and immunomodulatory treatment. European journal of neurology 20080401
Structural basis for recognition of Co2+ by RNA aptamers. The FEBS journal 20080401
Label-free sequence-specific DNA sensing using copper-enhanced anodic stripping of purine bases at boron-doped diamond electrodes. Analytical chemistry 20080401
Purine-containing cucurbitane triterpenoids from Cucurbita pepo cv dayangua. Phytochemistry 20080401
SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout. Nature genetics 20080401
Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner. The Journal of general virology 20080401
A study on the inhibition of adenosine deaminase. Journal of enzyme inhibition and medicinal chemistry 20080401
Acarbose alleviates rise in plasma uric acid concentration induced by sucrose ingestion. International journal of clinical pharmacology and therapeutics 20080401
Anti proliferative activity of ELACY (CP-4055) in combination with cloretazine (VNP40101M), idarubicin, gemcitabine, irinotecan and topotecan in human leukemia and lymphoma cells. Leukemia & lymphoma 20080401
Use of TAGVHD warnings in patients receiving purine analogue chemotherapy. Transfusion medicine (Oxford, England) 20080401
Cladribine in indolent non-Hodgkin's lymphoma. Expert review of anticancer therapy 20080401
[Definition and classification of hyperuricemia]. Nihon rinsho. Japanese journal of clinical medicine 20080401
[Urate production and regulation]. Nihon rinsho. Japanese journal of clinical medicine 20080401
[Molecular mechanisms of urate transport in renal tubules: localization and function of urate transporters]. Nihon rinsho. Japanese journal of clinical medicine 20080401
[Idiopathic hyperuricemia with overproduction of uric acid]. Nihon rinsho. Japanese journal of clinical medicine 20080401
[Deficiencies of hypoxanthine guanine phosphoribosyltransferase (HPRT)]. Nihon rinsho. Japanese journal of clinical medicine 20080401
[Pathophysiology and treatment of secondary hyperuricemia]. Nihon rinsho. Japanese journal of clinical medicine 20080401
[How do we set the standard value of serum uric acid levels?]. Nihon rinsho. Japanese journal of clinical medicine 20080401
[AMPD genes and urate metabolism]. Nihon rinsho. Japanese journal of clinical medicine 20080401
[Adenine phosphoribosyltransferase deficiency and its purine metabolism]. Nihon rinsho. Japanese journal of clinical medicine 20080401
Genetic variants associated with arsenic susceptibility: study of purine nucleoside phosphorylase, arsenic (+3) methyltransferase, and glutathione S-transferase omega genes. Environmental health perspectives 20080401
In vivo response to methotrexate forecasts outcome of acute lymphoblastic leukemia and has a distinct gene expression profile. PLoS medicine 20080401
Acute tumor lysis syndrome during oral fludarabine treatment for chronic lymphocytic leukemia. Role of treatment with rasburicase. Onkologie 20080401
Investigations of oligonucleotide usage variance within and between prokaryotes. PLoS computational biology 20080401
Beyond the guidelines in the treatment of peripheral T-cell lymphoma: new drug development. Journal of the National Comprehensive Cancer Network : JNCCN 20080401
Role of phosphodiesterase 5 in synaptic plasticity and memory. Neuropsychiatric disease and treatment 20080401
Alemtuzumab in the up-front setting. Therapeutics and clinical risk management 20080401
Treating refractory leukemias in childhood, role of clofarabine. Therapeutics and clinical risk management 20080401
6-(2-Chloro-benzyl-amino)purinium tetra-chlorido(dimethyl sulfoxide-κO)(nitrosyl-κN)ruthenate(III) monohydrate. Acta crystallographica. Section E, Structure reports online 20080401
4-Methyl-6-phenyl-pyrimidin-2-amine. Acta crystallographica. Section E, Structure reports online 20080401
Complex effects of foamy virus central purine-rich regions on viral replication. Virology 20080330
A proton-mediated conformational shift identifies a mobile pore-lining cysteine residue (Cys-561) in human concentrative nucleoside transporter 3. The Journal of biological chemistry 20080328
Consequences of impaired purine recycling in dopaminergic neurons. Neuroscience 20080327
Structural studies of thiamin monophosphate kinase in complex with substrates and products. Biochemistry 20080325
Triplex formation by pyrene-labelled probes for nucleic acid detection in fluorescence assays. Chembiochem : a European journal of chemical biology 20080325
Still looking for the magic spot: the crystallographically defined binding site for ppGpp on RNA polymerase is unlikely to be responsible for rRNA transcription regulation. Journal of molecular biology 20080321
Synthesis of novel C6-phosphonated purine nucleosides under microwave irradiation by SNAr-Arbuzov reaction. The Journal of organic chemistry 20080321
The current state of serum biomarkers of hepatotoxicity. Toxicology 20080320
Structural polymorphism exhibited by a homopurine.homopyrimidine sequence found at the right end of human c-jun protooncogene. Archives of biochemistry and biophysics 20080315
A sensitive and specific liquid chromatography-mass spectrometry method for determination of metacavir in rat plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080315
Drug transporters: recent advances concerning BCRP and tyrosine kinase inhibitors. British journal of cancer 20080311
Tryptophan-free human PNP reveals catalytic site interactions. Biochemistry 20080311
Mimicking phosphorylation of Ser-74 on human deoxycytidine kinase selectively increases catalytic activity for dC and dC analogues. FEBS letters 20080305
MicroRNA399 is a long-distance signal for the regulation of plant phosphate homeostasis. The Plant journal : for cell and molecular biology 20080301
Suppression of inflammatory and immune responses by the A(2A) adenosine receptor: an introduction. British journal of pharmacology 20080301
Leishmania mexicana amazonensis: plasma membrane adenine nucleotide translocator and chemotaxis. Experimental parasitology 20080301
Novel mutations of NP in two patients with purine nucleoside phosphorylase deficiency. Clinical biochemistry 20080301
Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides. Bioorganic & medicinal chemistry 20080301
PTD-mediated delivery of anti-cell death proteins/peptides and therapeutic enzymes. Advanced drug delivery reviews 20080301
Oxidation of mitochondrial deoxynucleotide pools by exposure to sodium nitroprusside induces cell death. DNA repair 20080301
Lethal mutagenesis of picornaviruses with N-6-modified purine nucleoside analogues. Antimicrobial agents and chemotherapy 20080301
Comprehensive and quantitative proteome profiling of the mouse liver and plasma. Hepatology (Baltimore, Md.) 20080301
p53-dependent global nucleotide excision repair of cisplatin-induced intrastrand cross links in human cells. Mutagenesis 20080301
Metabolism of halophilic archaea. Extremophiles : life under extreme conditions 20080301
The attachment of amino fragment to purine: inner-shell structures and spectra. Journal of synchrotron radiation 20080301
The energetics of rearrangement and water elimination reactions in the radiolysis of the DNA bases in aqueous solution (eaq- and *OH attack): DFT calculations. Radiation research 20080301
Emerging drugs for rarer chronic lymphoid leukemias. Expert opinion on emerging drugs 20080301
Novel monoclonal antibodies for the treatment of chronic lymphocytic leukemia. Current cancer drug targets 20080301
The clinical spectrum of IgM-related amyloidosis: a French nationwide retrospective study of 72 patients. Medicine 20080301
Structural studies of RNA/DNA polypurine tracts. Chemistry & biology 20080301
High-resolution NMR analysis of the conformations of native and base analog substituted retroviral and LTR-retrotransposon PPT primers. Chemistry & biology 20080301
Phosphorylation-independent regulation of the diguanylate cyclase WspR. PLoS biology 20080301
P2 receptors in cardiovascular regulation and disease. Purinergic signalling 20080301
Internalization and desensitization of adenosine receptors. Purinergic signalling 20080301
Pyrazolo-triazolo-pyrimidines as adenosine receptor antagonists: Effect of the N-5 bond type on the affinity and selectivity at the four adenosine receptor subtypes. Purinergic signalling 20080301
Remyelination after chronic spinal cord injury is associated with proliferation of endogenous adult progenitor cells after systemic administration of guanosine. Purinergic signalling 20080301
UCB Pharma research day-25 October 2007 'Glia-neuron interactions and purinergic receptors in neurological disorders'. Purinergic signalling 20080301
Plasmodium-induced inflammation by uric acid. PLoS pathogens 20080301
[Enhancement of GFP expression by Kozak sequence +4G in HEK293 cells]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20080301
Alcohol related changes in regulation of NMDA receptor functions. Current neuropharmacology 20080301
Voltammetric Behavior of o-Nitrophenol and Damage to DNA. International journal of molecular sciences 20080301
Dietary berries and ellagic acid prevent oxidative DNA damage and modulate expression of DNA repair genes. International journal of molecular sciences 20080301
Alemtuzumab in the treatment of fludarabine refractory B-cell chronic lymphocytic leukemia (CLL). Biologics : targets & therapy 20080301
Pitfalls, prevention, and treatment of hyperuricemia during tumor lysis syndrome in the era of rasburicase (recombinant urate oxidase). Biologics : targets & therapy 20080301
A three-state model for the photophysics of guanine. Journal of the American Chemical Society 20080227
Transition state structure of E. coli tRNA-specific adenosine deaminase. Journal of the American Chemical Society 20080227
Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases. Journal of medicinal chemistry 20080227
Rituximab-CHOP induced interstitial pneumonitis in patients with disseminated extranodal marginal zone B cell lymphoma. Yonsei medical journal 20080227
Altered thermodynamics from remote mutations altering human toward bovine purine nucleoside phosphorylase. Biochemistry 20080226
Remote mutations alter transition-state structure of human purine nucleoside phosphorylase. Biochemistry 20080226
Second-sphere amino acids contribute to transition-state structure in bovine purine nucleoside phosphorylase. Biochemistry 20080226
Substrate orientation in xanthine oxidase: crystal structure of enzyme in reaction with 2-hydroxy-6-methylpurine. The Journal of biological chemistry 20080222
Chemical properties of oxopropenyl adducts of purine and pyrimidine nucleosides and their reactivity toward amino acid cross-link formation. Journal of the American Chemical Society 20080220
Transition-state interactions revealed in purine nucleoside phosphorylase by binding isotope effects. Journal of the American Chemical Society 20080220
Can an atomic force microscope sequence DNA using a nanopore? Biophysical journal 20080215
Characters of very ancient proteins. Biochemical and biophysical research communications 20080215
Isolation of inhibitory RNA aptamers against severe acute respiratory syndrome (SARS) coronavirus NTPase/Helicase. Biochemical and biophysical research communications 20080215
Block of inhibitory junction potentials and TREK-1 channels in murine colon by Ca2+ store-active drugs. The Journal of physiology 20080215
Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB. Journal of medicinal chemistry 20080214
Structural diversity and plasticity associated with nucleotides targeting orotidine monophosphate decarboxylase. Journal of medicinal chemistry 20080214
Autocatalytic demetalation of a Zn(salphen) complex provoked by unprotected N-heterocycles. Dalton transactions (Cambridge, England : 2003) 20080214
Studies on umami taste. Synthesis of new guanosine 5'-phosphate derivatives and their synergistic effect with monosodium glutamate. Journal of agricultural and food chemistry 20080213
Antioxidant and prooxidant properties of ascorbic acid on hepatic dysfunction induced by cold ischemia/reperfusion. European journal of pharmacology 20080212
Atomic detail investigation of the structure and dynamics of DNA.RNA hybrids: a molecular dynamics study. The journal of physical chemistry. B 20080207
Acute and chronic effects of some dietary bioactive compounds on folic acid uptake and on the expression of folic acid transporters by the human trophoblast cell line BeWo. The Journal of nutritional biochemistry 20080201
Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors. European journal of medicinal chemistry 20080201
Role of ionization of the phosphate cosubstrate on phosphorolysis by purine nucleoside phosphorylase (PNP) of bacterial (E. coli) and mammalian (human) origin. European biophysics journal : EBJ 20080201
Purine nucleobase transport in the intraerythrocytic malaria parasite. International journal for parasitology 20080201
Characterization of cellular chemical dynamics using combined microfluidic and Raman techniques. Analytical and bioanalytical chemistry 20080201
P2Y1 receptors mediate inhibitory neuromuscular transmission and enteric neuronal activation in small intestine. Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080201
Fludarabine induces growth arrest and apoptosis of cytokine- or alloantigen-stimulated peripheral blood mononuclear cells, and decreases production of Th1 cytokines via inhibition of nuclear factor kappaB. Bone marrow transplantation 20080201
Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides. Bioorganic & medicinal chemistry 20080201
Effects of exercise and grape juice ingestion in combination on plasma concentrations of purine bases and uridine. Clinica chimica acta; international journal of clinical chemistry 20080201
Pathogen resistance of transgenic tobacco plants producing caffeine. Phytochemistry 20080201
Identification, biochemical characterization, and subcellular localization of allantoate amidohydrolases from Arabidopsis and soybean. Plant physiology 20080201
Caffeine and related purine alkaloids: biosynthesis, catabolism, function and genetic engineering. Phytochemistry 20080201
Cladribine combined with high doses of arabinoside cytosine, mitoxantrone, and G-CSF (CLAG-M) is a highly effective salvage regimen in patients with refractory and relapsed acute myeloid leukemia of the poor risk: a final report of the Polish Adult Leukemia Group. European journal of haematology 20080201
Synthesis and anti-HIV activity of 2'-fluorine modified nucleoside phosphonates: analogs of GS-9148. Bioorganic & medicinal chemistry letters 20080201
An atypical orthologue of 6-pyruvoyltetrahydropterin synthase can provide the missing link in the folate biosynthesis pathway of malaria parasites. Molecular microbiology 20080201
Fermentation characteristics and microbial growth promoted by diets including two-phase olive cake in continuous fermenters. Journal of animal physiology and animal nutrition 20080201
Bulky DNA lesions induced by reactive oxygen species. Chemical research in toxicology 20080201
[Adenylosuccinate lyase deficiency: an unusual cause of neonatal seizure]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20080201
Steric block high affinity oligonucleotide analogues: a new tool for mapping RNA-protein binding sites. Nucleosides, nucleotides & nucleic acids 20080201
Monte carlo simulations of site-specific radical attack to DNA bases. Radiation research 20080201
Uric acid administration in patients with acute stroke: a novel approach to neuroprotection. Expert review of neurotherapeutics 20080201
Nucleotide biosynthesis is critical for growth of bacteria in human blood. PLoS pathogens 20080201
A purine nucleoside analogue-acyclovir [9-(2-hydroxyethoxymethyl)-9h-guanine] reversibly impairs testicular functions in mouse. The Journal of toxicological sciences 20080201
The direct precursor of the pyrimidine moiety of thiamin is not urocanic acid but histidine in Saccharomyces cerevisiae. Journal of nutritional science and vitaminology 20080201
Variation in molybdenum content across broadly distributed populations of Arabidopsis thaliana is controlled by a mitochondrial molybdenum transporter (MOT1). PLoS genetics 20080201
Review of pemetrexed in combination with cisplatin for the treatment of malignant pleural mesothelioma. Therapeutics and clinical risk management 20080201
Transport of [14C]hypoxanthine by sheep choroid plexus epithelium as a monolayer in primary culture: Na+-dependent and Na+-independent uptake by the apical membrane and rapid intracellular metabolic conversion to nucleotides. Neuroscience letters 20080131
Barrier-free proton transfer in the valence anion of 2'-deoxyadenosine-5'-monophosphate. II. A computational study. The Journal of chemical physics 20080128
Structural requirements for the activation of Escherichia coli CTP synthase by the allosteric effector GTP are stringent, but requirements for inhibition are lax. The Journal of biological chemistry 20080125
Structures of dimeric nonstandard nucleotide triphosphate pyrophosphatase from Pyrococcus horikoshii OT3: functional significance of interprotomer conformational changes. Journal of molecular biology 20080125
L-Enantiomers of transition state analogue inhibitors bound to human purine nucleoside phosphorylase. Journal of the American Chemical Society 20080123
Fluorescence and electrochemical detection of pyrimidine/purine transversion by a ferrocenyl aminonaphthyridine derivative. Organic & biomolecular chemistry 20080121
Synthesis of modified DNA by PCR with alkyne-bearing purines followed by a click reaction. Organic letters 20080117
DNA-protein cross-links between guanine and lysine depend on the mechanism of oxidation for formation of C5 vs C8 guanosine adducts. Journal of the American Chemical Society 20080116
Synthesis of guanidino analogues of PMPDAP and their immunobiological activity. Bioorganic & medicinal chemistry 20080115
Environmental restrictions within tumor ecosystems select for a convergent, hypoxia-resistant phenotype of cancer stem cells. Cell cycle (Georgetown, Tex.) 20080115
The G22A polymorphism of the ADA gene and susceptibility to autism spectrum disorders. Journal of autism and developmental disorders 20080101
Immunomodulatory effect of the purine nucleoside inosine following spinal cord contusion injury in rat. Spinal cord 20080101
Synthesis and characterization of some pyrimidine, purine, amino acid and mixed ligand complexes. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080101
[Kelley-Seegmiller syndrome]. Klinische Padiatrie 20080101
Is uric acid itself a player or a bystander in the pathophysiology of chronic heart failure? Medical hypotheses 20080101
A computational study on DNA bases interactions with dinuclear tetraacetato-diaqua-dirhodium(II,II) complex. Journal of inorganic biochemistry 20080101
Wavelength dependant quenching of 2,5-diphenyloxazole fluorescence by nucleotides. Journal of fluorescence 20080101
Extremely low frequency (ELF) magnetic fields enhance chemically induced formation of apurinic/apyrimidinic (AP) sites in A172 cells. International journal of radiation biology 20080101
Regulation of cytokinin biosynthesis, compartmentalization and translocation. Journal of experimental botany 20080101
Compartmentalization of non-adenine nucleotides in anoxic cardiac myocytes. Basic research in cardiology 20080101
Chemoenzymatic synthesis and antiviral evaluation of conformationally constrained and 3'-methyl-branched carbanucleosides using both enantiomers of the same building block. Bioorganic & medicinal chemistry 20080101
Association study of human MTH1 Ile45Thr polymorphism with sporadic Parkinson's disease. European neurology 20080101
Guarana (Paullinia cupana var. sorbilis), an anciently consumed stimulant from the Amazon rain forest: the seeded-fruit transcriptome. Plant cell reports 20080101
5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species. Bioorganic & medicinal chemistry 20080101
NF45 and NF90 in murine seminiferous epithelium: potential role in SP-10 gene transcription. Journal of andrology 20080101
Purinergic signaling in the inner ear. Hearing research 20080101
Mycophenolate mofetil in primary glomerulopathies. Kidney international 20080101
Functional expression of the adenosine A1 receptor in rabbit lacrimal gland. Experimental eye research 20080101
Mutational inhibition of ligation in the hairpin ribozyme: substitutions of conserved nucleobases A9 and A10 destabilize tertiary structure and selectively promote cleavage. RNA (New York, N.Y.) 20080101
Solvable models of neighbor-dependent substitution processes. Mathematical biosciences 20080101
Unambiguous structural elucidation of base-modified purine nucleosides using NMR. Magnetic resonance in chemistry : MRC 20080101
Activation of adenosine 2A receptors preserves structure and function of podocytes. Journal of the American Society of Nephrology : JASN 20080101
Prediction of elution bandwidth for purine compounds by a retention model in reversed-phase HPLC with linear-gradient elution. Journal of separation science 20080101
Purine sensing by riboswitches. Biology of the cell 20080101
Paracrinicity: the story of 30 years of cellular pituitary crosstalk. Journal of neuroendocrinology 20080101
Studies on the reactivity of organometallic Ru-, Rh- and Os-pta complexes with DNA model compounds. Journal of inorganic biochemistry 20080101
Interactions between barley grain processing and source of supplemental dietary fat on nitrogen metabolism and urea-nitrogen recycling in dairy cows. Journal of dairy science 20080101
Evaluation of nitrogen utilization and the effects of monensin in dairy cows fed brown midrib corn silage. Journal of dairy science 20080101
High-resolution analysis of condition-specific regulatory modules in Saccharomyces cerevisiae. Genome biology 20080101
Specificity of DNA-binding by the FAX-1 and NHR-67 nuclear receptors of Caenorhabditis elegans is partially mediated via a subclass-specific P-box residue. BMC molecular biology 20080101
Using 454 technology for long-PCR based sequencing of the complete mitochondrial genome from single Haemonchus contortus (Nematoda). BMC genomics 20080101
LTRharvest, an efficient and flexible software for de novo detection of LTR retrotransposons. BMC bioinformatics 20080101
Substrate specificity of new methyl-directed DNA endonuclease GlaI. BMC molecular biology 20080101
The amphioxus (Branchiostoma floridae) genome contains a highly diversified set of G protein-coupled receptors. BMC evolutionary biology 20080101
rosy Function is required for juvenile hormone effects in Drosophila melanogaster. Genetics 20080101
Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity. Genome biology 20080101
Pleiotropic phenotypes of a Yersinia enterocolitica flhD mutant include reduced lethality in a chicken embryo model. BMC microbiology 20080101
The fight against drug-resistant malaria: novel plasmodial targets and antimalarial drugs. Current medicinal chemistry 20080101
Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells. Molecular cancer 20080101
Effects of a supplement designed to increase ATP levels on muscle strength, power output, and endurance. Journal of the International Society of Sports Nutrition 20080101
Antimicrobial properties of milkfat globule membrane fractions. Journal of food protection 20080101
Early and transient reverse transcription during primary deltaretroviral infection of sheep. Retrovirology 20080101
Equilibrium model selection: dTTP induced R1 dimerization. BMC systems biology 20080101
Up regulation in gene expression of chromatin remodelling factors in cervical intraepithelial neoplasia. BMC genomics 20080101
Multiple strand displacement amplification of mitochondrial DNA from clinical samples. BMC medical genetics 20080101
Wound healing in patients with cancer. Eplasty 20080101
[Nephrolithiasis in patients with intestinal diseases]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101
Ligand-induced sequestering of branchpoint sequence allows conditional control of splicing. BMC molecular biology 20080101
Using a logical model to predict the growth of yeast. BMC bioinformatics 20080101
Proteomic analysis of the secretome of Leishmania donovani. Genome biology 20080101
Orphan SelD proteins and selenium-dependent molybdenum hydroxylases. Biology direct 20080101
Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna. Genome biology 20080101
6th international symposium on retroviral nucleocapsid. Retrovirology 20080101
Novel methodology for construction and pruning of quasi-median networks. BMC bioinformatics 20080101
Reconstruction and analysis of the genetic and metabolic regulatory networks of the central metabolism of Bacillus subtilis. BMC systems biology 20080101
The combination of clofarabine and cytarabine in pediatric relapsed acute lymphoblastic leukemia: a case report. Chemotherapy 20080101
Different bacterial gene expression patterns and attenuated host immune responses are associated with the evolution of low-level vancomycin resistance during persistent methicillin-resistant Staphylococcus aureus bacteraemia. BMC microbiology 20080101
Spontaneous DNA repair increases during hemodialysis. Nephron. Clinical practice 20080101
[The pathogenetic role of the serotonin-histamine-cyclic nucleotide system in ulcerogenesis]. Vestnik Rossiiskoi akademii meditsinskikh nauk 20080101
[Outpatient diagnostics of the initial stage of essential hypertension]. Klinicheskaia meditsina 20080101
Computational identification of obligatorily autocatalytic replicators embedded in metabolic networks. Genome biology 20080101
Treatment of experimental colitis in mice with LMP-420, an inhibitor of TNF transcription. Journal of inflammation (London, England) 20080101
Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo. PloS one 20080101
Endogenous retroviruses of the chicken genome. Biology direct 20080101
Systems analysis of metabolism in the pathogenic trypanosomatid Leishmania major. Molecular systems biology 20080101
Antiparasitic chemotherapy: tinkering with the purine salvage pathway. Advances in experimental medicine and biology 20080101
Purine and pyrimidine metabolism in Leishmania. Advances in experimental medicine and biology 20080101
Computational evaluation of TIS annotation for prokaryotic genomes. BMC bioinformatics 20080101
Gene targeting in adult rhesus macaque fibroblasts. BMC biotechnology 20080101
par genes in Mycobacterium bovis and Mycobacterium smegmatis are arranged in an operon transcribed from 'SigGC' promoters. BMC microbiology 20080101
Novel forms of Paired-like homeodomain transcription factor 2 (PITX2): generation by alternative translation initiation and mRNA splicing. BMC molecular biology 20080101
[The treatment of Waldenström macroglobulinemia and the therapy of diseases caused by monoclonal IgM gammaglobulin]. Vnitrni lekarstvi 20080101
Current developments in the synthesis and biological activity of aza-C-nucleosides: immucillins and related compounds. Current medicinal chemistry 20080101
OppA, the ecto-ATPase of Mycoplasma hominis induces ATP release and cell death in HeLa cells. BMC microbiology 20080101
Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC genomics 20080101
Polymorphisms of Glutathione S-transferases Omega-1 among ethnic populations in China. BMC genetics 20080101
Perceiving molecular evolution processes in Escherichia coli by comprehensive metabolite and gene expression profiling. Genome biology 20080101
Prodrug converting enzyme gene delivery by L. monocytogenes. BMC cancer 20080101
Significance analysis of microarray for relative quantitation of LC/MS data in proteomics. BMC bioinformatics 20080101
Nuclear Factor-kappa B as a Resistance Factor to Platinum-Based Antineoplasic Drugs. Metal-based drugs 20080101
Novel therapies for anti-neutrophil cytoplasmic antibody-associated vasculitis. Drugs 20080101
Metabolic pathways of the wheat (Triticum aestivum) endosperm amyloplast revealed by proteomics. BMC plant biology 20080101
High-resolution study of nuclear magnetic relaxation dispersion of purine nucleotides: effects of spin-spin coupling. Solid state nuclear magnetic resonance 20080101
Regulation of 5'-adenosine monophosphate deaminase in the freeze tolerant wood frog, Rana sylvatica. BMC biochemistry 20080101
Arsenic-based antineoplastic drugs and their mechanisms of action. Metal-based drugs 20080101
A novel splice-site mutation of TULP1 underlies severe early-onset retinitis pigmentosa in a consanguineous Israeli Muslim Arab family. Molecular vision 20080101
A mathematical model of glutathione metabolism. Theoretical biology & medical modelling 20080101
Expression analysis of G Protein-Coupled Receptors in mouse macrophages. Immunome research 20080101
The Mycobacterium tuberculosis Rv2540c DNA sequence encodes a bifunctional chorismate synthase. BMC biochemistry 20080101
Processing of genome 5' termini as a strategy of negative-strand RNA viruses to avoid RIG-I-dependent interferon induction. PloS one 20080101
Comparative analysis of sequence features involved in the recognition of tandem splice sites. BMC genomics 20080101
The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis. BMC evolutionary biology 20080101
Reconstructing networks of pathways via significance analysis of their intersections. BMC bioinformatics 20080101
Anti-inflammatory preconditioning by agonists of adenosine A1 receptor. PloS one 20080101
Uncovering genes with divergent mRNA-protein dynamics in Streptomyces coelicolor. PloS one 20080101
Effects of subminimum inhibitory concentrations of antibiotics on the Pasteurella multocida proteome: a systems approach. Comparative and functional genomics 20080101
Bioinformatic analyses of mammalian 5'-UTR sequence properties of mRNAs predicts alternative translation initiation sites. BMC bioinformatics 20080101
Microsatellite evolution: Mutations, sequence variation, and homoplasy in the hypervariable avian microsatellite locus HrU10. BMC evolutionary biology 20080101
Cytotoxic nucleoside analogues: different strategies to improve their clinical efficacy. Current medicinal chemistry 20080101
Impact of point-mutations on the hybridization affinity of surface-bound DNA/DNA and RNA/DNA oligonucleotide-duplexes: comparison of single base mismatches and base bulges. BMC biotechnology 20080101
Concordant gene expression in leukemia cells and normal leukocytes is associated with germline cis-SNPs. PloS one 20080101
The BsaHI restriction-modification system: cloning, sequencing and analysis of conserved motifs. BMC molecular biology 20080101
PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression. BMC genomics 20080101
Genomic analysis of post-mating changes in the honey bee queen (Apis mellifera). BMC genomics 20080101
Analysis by siRNA_profile program displays novel thermodynamic characteristics of highly functional siRNA molecules. Source code for biology and medicine 20080101
Trait-trait dynamic interaction: 2D-trait eQTL mapping for genetic variation study. BMC genomics 20080101
Ligand specificity of group I biotin protein ligase of Mycobacterium tuberculosis. PloS one 20080101
The binary protein interactome of Treponema pallidum--the syphilis spirochete. PloS one 20080101
Life-cycle and genome of OtV5, a large DNA virus of the pelagic marine unicellular green alga Ostreococcus tauri. PloS one 20080101
Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species. BMC genomics 20080101
Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts. Critical care (London, England) 20080101
Genome-wide survey of allele-specific splicing in humans. BMC genomics 20080101
Botulinum toxin: treatment of self-mutilation in patients with Lesch-Nyhan syndrome. Clinical neuropharmacology 20080101
'Systems toxicology' approach identifies coordinated metabolic responses to copper in a terrestrial non-model invertebrate, the earthworm Lumbricus rubellus. BMC biology 20080101
Adenosine transporter ENT4 is a direct target of EWS/WT1 translocation product and is highly expressed in desmoplastic small round cell tumor. PloS one 20080101
Analysis of the EIAV Rev-responsive element (RRE) reveals a conserved RNA motif required for high affinity Rev binding in both HIV-1 and EIAV. PloS one 20080101
Metabolism of nicotinamide, adenine and inosine in developing microspore-derived canola (Brassica napus) embryos. Plant physiology and biochemistry : PPB 20080101
Genome-based construction of the metabolic pathways of Orientia tsutsugamushi and comparative analysis within the Rickettsiales order. Comparative and functional genomics 20080101
GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors. BMC bioinformatics 20080101
Identification of differentially expressed proteins in spontaneous thymic lymphomas from knockout mice with deletion of p53. Proteome science 20080101
Two specific drugs, BMS-345541 and purvalanol A induce apoptosis of HTLV-1 infected cells through inhibition of the NF-kappaB and cell cycle pathways. AIDS research and therapy 20080101
The highest-copy repeats are methylated in the small genome of the early divergent vascular plant Selaginella moellendorffii. BMC genomics 20080101
Genomic mid-range inhomogeneity correlates with an abundance of RNA secondary structures. BMC genomics 20080101
Barnase as a new therapeutic agent triggering apoptosis in human cancer cells. PloS one 20080101
Maintenance metabolism and carbon fluxes in Bacillus species. Microbial cell factories 20080101
A naturally occurring omega current in a Kv3 family potassium channel from a platyhelminth. BMC neuroscience 20080101
Cortical layer 1 and layer 2/3 astrocytes exhibit distinct calcium dynamics in vivo. PloS one 20080101
A Francisella tularensis Schu S4 purine auxotroph is highly attenuated in mice but offers limited protection against homologous intranasal challenge. PloS one 20080101
Biochemical characterization and cellular imaging of a novel, membrane permeable fluorescent cAMP analog. BMC biochemistry 20080101
The role of upstream sequences in selecting the reading frame on tmRNA. BMC biology 20080101
Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia. Biology direct 20080101
A cryptic promoter in the first exon of the SPG4 gene directs the synthesis of the 60-kDa spastin isoform. BMC biology 20080101
Investigating selection on viruses: a statistical alignment approach. BMC bioinformatics 20080101
Articulation of three core metabolic processes in Arabidopsis: fatty acid biosynthesis, leucine catabolism and starch metabolism. BMC plant biology 20080101
Thermodynamics of binding of divalent magnesium and manganese to uridine phosphates: implications for diabetes-related hypomagnesaemia and carbohydrate biocatalysis. Chemistry Central journal 20080101
Global regulation of nucleotide biosynthetic genes by c-Myc. PloS one 20080101
Genome holography: deciphering function-form motifs from gene expression data. PloS one 20080101
Metabolic control analysis: a tool for designing strategies to manipulate metabolic pathways. Journal of biomedicine & biotechnology 20080101
The transcriptional program underlying the physiology of clostridial sporulation. Genome biology 20080101
Allantoin as a marker of oxidative stress in human erythrocytes. Clinical chemistry and laboratory medicine 20080101
A new perspective on phylogeny and evolution of tetraodontiform fishes (Pisces: Acanthopterygii) based on whole mitochondrial genome sequences: basal ecological diversification? BMC evolutionary biology 20080101
Structural analysis of urate oxidase in complex with its natural substrate inhibited by cyanide: mechanistic implications. BMC structural biology 20080101
Growth rate regulated genes and their wide involvement in the Lactococcus lactis stress responses. BMC genomics 20080101
Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study. PloS one 20080101
Multiple functions for ORF75c in murid herpesvirus-4 infection. PloS one 20080101
Characterization of new IS elements and studies of their dispersion in two subspecies of Leifsonia xyli. BMC microbiology 20080101
Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening. BMC genomics 20080101
Multi-factorial somato-dendritic regulation of phasic spike discharge in vasopressin neurons. Progress in brain research 20080101
Overexpression of the riboflavin biosynthetic pathway in Pichia pastoris. Microbial cell factories 20080101
Remodeling of the Streptococcus agalactiae transcriptome in response to growth temperature. PloS one 20080101
ATP release from vascular endothelia occurs across Cx43 hemichannels and is attenuated during hypoxia. PloS one 20080101
Conserved upstream open reading frames in higher plants. BMC genomics 20080101
Regulation of cancer progression by inhibition of angiogenesis and induction of apoptosis. Verhandelingen - Koninklijke Academie voor Geneeskunde van Belgie 20080101
Proteomic approaches in understanding action mechanisms of metal-based anticancer drugs. Metal-based drugs 20080101
Enzymatic synthesis of multiple spin-labeled DNA. Angewandte Chemie (International ed. in English) 20080101
Differential control of Zap1-regulated genes in response to zinc deficiency in Saccharomyces cerevisiae. BMC genomics 20080101
Cytotoxic and genotoxic effects of methotrexate in germ cells of male Swiss mice. Mutation research 20080101
In vivo analysis of Caenorhabditis elegans noncoding RNA promoter motifs. BMC molecular biology 20080101
The evolutionary origin of the Runx/CBFbeta transcription factors--studies of the most basal metazoans. BMC evolutionary biology 20080101
Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity. Molecular systems biology 20080101
Complexes of Cu(II) ions and noncovalent interactions in systems with L-aspartic acid and cytidine-5'-monophosphate. Bioinorganic chemistry and applications 20080101
P2x7 deficiency suppresses development of experimental autoimmune encephalomyelitis. Journal of neuroinflammation 20080101
Characterization of expressed sequence tags from a full-length enriched cDNA library of Cryptomeria japonica male strobili. BMC genomics 20080101
Novel therapies in genitourinary cancer: an update. Journal of hematology & oncology 20080101
Complete genome of Phenylobacterium zucineum--a novel facultative intracellular bacterium isolated from human erythroleukemia cell line K562. BMC genomics 20080101
Successful long-term monotherapy with rituximab in a patient with chronic lymphocytic leukemia of the B-cell-lineage: a case report. Journal of medical case reports 20080101
Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate. BMC genomics 20080101
Streptococcus pneumoniae early response genes to human lung epithelial cells. BMC research notes 20080101
Integrative analyses of genetic variation in enzyme activities of primary carbohydrate metabolism reveal distinct modes of regulation in Arabidopsis thaliana. Genome biology 20080101
A DNA and morphology based phylogenetic framework of the ant genus Lasius with hypotheses for the evolution of social parasitism and fungiculture. BMC evolutionary biology 20080101
Origin of co-expression patterns in E. coli and S. cerevisiae emerging from reverse engineering algorithms. PloS one 20080101
Mizoribine treatment of young patients with severe lupus nephritis: a clinicopathologic study by the tohoku pediatric study group. Nephron. Clinical practice 20080101
A translation initiation element specific to mRNAs with very short 5'UTR that also regulates transcription. PloS one 20080101
Extensive adaptive changes occur in the transcriptome of Streptococcus agalactiae (group B streptococcus) in response to incubation with human blood. PloS one 20080101
Global self-organization of the cellular metabolic structure. PloS one 20080101
Longer first introns are a general property of eukaryotic gene structure. PloS one 20080101
Triplex glue by synthesizing conjugated flexible intercalators. Nucleic acids symposium series (2004) 20080101
Synthesis of the new nucleoside analogue connecting 2-amino-6-vinylpurine to the 2'-deoxyribose skeleton via the methylene linker. Nucleic acids symposium series (2004) 20080101
Repair of DNA-protein crosslink damage: coordinated actions of nucleotide excision repair and homologous recombination. Nucleic acids symposium series (2004) 20080101
Synthesis and properties of (alpha-P-borano)-nucleoside 5'-triphosphate analogues as potential antiviral agents. Nucleic acids symposium series (2004) 20080101
The interaction between the purine motif triplex and the triplex DNA-binding domain of Saccharomyces cerevisiae Stm1 protein. Nucleic acids symposium series (2004) 20080101
Efficient preparation of xanthine-containing oligodeoxynucleotide from oxanine-containing oligodeoxynucleotide, catalyzed by N alpha-acetyl-L-histidine. Nucleic acids symposium series (2004) 20080101
Reactivity of oxanine: efficient fabrication of DNA microarray by using oxanine-containing DNA oligomer as probe molecule. Nucleic acids symposium series (2004) 20080101
Synthesis and some transformation of acyclic nucleotide phosphonate analogues with triple bond. Nucleic acids symposium series (2004) 20080101
Coupled biocatalysts applied to the synthesis of nucleosides. Nucleic acids symposium series (2004) 20080101
Regioselective glycosylation of 7-azapteridines and conversion of the 7-azapteridine nucleosides into 6-azapurine nucleosides. Nucleic acids symposium series (2004) 20080101
Design and synthesis of 1-(beta-D-ribofuranosyl)imidazo[4,5-c]pyrazoles as 5:5 bicyclic analogs of purine nucleosides. Nucleic acids symposium series (2004) 20080101
Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives. Nucleic acids symposium series (2004) 20080101
The novel unsaturated acyclic nucleoside analogues: cytostatic and antiviral activity evaluations. Nucleic acids symposium series (2004) 20080101
Synthesis of novel cyclopropyl nucleoside analogues as potential antiherpetic agent. Nucleic acids symposium series (2004) 20080101
Hetero-expanded purine nucleosides. Design, synthesis and preliminary biological activity. Nucleic acids symposium series (2004) 20080101
Synthesis of 2-chloro-N6-substituted-4'-thioadenosine-5'-N, N-dialkyluronamides as potent and selective A3 adenosine receptor antagonists. Nucleic acids symposium series (2004) 20080101
Synthesis and biological evaluation of 5''-iodoneplanocin A and its analogues. Nucleic acids symposium series (2004) 20080101
9-Deazaguanine derivatives: synthesis and inhibitory properties as multi-substrate analogue inhibitors of mammalian PNPs. Nucleic acids symposium series (2004) 20080101
Thermodynamic studies of interactions of calf spleen PNP with acyclic phosphonate inhibitors. Nucleic acids symposium series (2004) 20080101
On the analysis of fluorimetric titration curves of purine nucleoside phosphorylase. Nucleic acids symposium series (2004) 20080101
Gene expression variation to predict 10-year survival in lymph-node-negative breast cancer. BMC cancer 20080101
A random shRNA-encoding library for phenotypic selection and hit-optimization. PloS one 20080101
Whole genome expression and biochemical correlates of extreme constitutional types defined in Ayurveda. Journal of translational medicine 20080101
Phosphoribosyl pyrophosphate synthetase activity affects growth and riboflavin production in Ashbya gossypii. BMC biotechnology 20080101
Automatic detection of exonic splicing enhancers (ESEs) using SVMs. BMC bioinformatics 20080101
Pharmacokinetics and transcriptional effects of the anti-salmon lice drug emamectin benzoate in Atlantic salmon (Salmo salar L.). BMC pharmacology 20080101
[The influence of purine nucleotides and adenosine on bioelectrical activity of bat (Pipistrellus nathusii) heart]. Kardiologiia 20080101
Assessment of Hematological and Biochemical parameters with extended D-Ribose ingestion. Journal of the International Society of Sports Nutrition 20080101
Transcriptomic analysis of the exit from dormancy of Aspergillus fumigatus conidia. BMC genomics 20080101
Metabolite profiling of human colon carcinoma--deregulation of TCA cycle and amino acid turnover. Molecular cancer 20080101
Mathematical models of folate-mediated one-carbon metabolism. Vitamins and hormones 20080101
Regulation of human dihydrofolate reductase activity and expression. Vitamins and hormones 20080101
Mitochondrial methylenetetrahydrofolate dehydrogenase, methenyltetrahydrofolate cyclohydrolase, and formyltetrahydrofolate synthetases. Vitamins and hormones 20080101
[Mitochondrial uncoupling proteins: regulation and physiological role]. Postepy biochemii 20080101
Epigenetic regulation of genomes: nutrient-specific modulation of genetic networks in bovine cells. Developments in biologicals 20080101
The role of antioxidant supplement in immune system, neoplastic, and neurodegenerative disorders: a point of view for an assessment of the risk/benefit profile. Nutrition journal 20080101
Bench-to-bedside review: adenosine receptors--promising targets in acute lung injury? Critical care (London, England) 20080101
The unfoldomics decade: an update on intrinsically disordered proteins. BMC genomics 20080101
Gene and pathway identification with Lp penalized Bayesian logistic regression. BMC bioinformatics 20080101
Performance of mitochondrial DNA mutations detecting early stage cancer. BMC cancer 20080101
Triamcinolone acetonide and anecortave acetate do not stimulate uveal melanoma cell growth. Molecular vision 20080101
Maternal Oct-4 is a potential key regulator of the developmental competence of mouse oocytes. BMC developmental biology 20080101
Effect of nucleoside and nucleotide reverse transcriptase inhibitors of HIV on endogenous nucleotide pools. Antiviral therapy 20080101
Ubiquitous water-soluble molecules in aquatic plant exudates determine specific insect attraction. PloS one 20080101
ITS-2 secondary structures and phylogeny of Anopheles culicifacies species. Bioinformation 20080101
RNomics and Modomics in the halophilic archaea Haloferax volcanii: identification of RNA modification genes. BMC genomics 20080101
Head-to-head right-handed cross-links of the antitumor-active bis(mu-N,N'-di-p-tolylformamidinato)dirhodium(II,II) unit with the dinucleotides d(GpA) and d(ApG). Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
Toxicogenomic response of Pseudomonas aeruginosa to ortho-phenylphenol. BMC genomics 20080101
The adenosine deaminase inhibitor erythro-9-[2-hydroxyl-3-nonyl]-adenine decreases intestinal permeability and protects against experimental sepsis: a prospective, randomised laboratory investigation. Critical care (London, England) 20080101
Design, synthesis and anticancer activity against the MCF-7 cell line of benzo-fused 1,4-dihetero seven- and six-membered tethered pyrimidines and purines. Current medicinal chemistry 20080101
Structural bioinformatics study of PNP from Listeria monocytogenes. Protein and peptide letters 20080101
Computational identification of three-way junctions in folded RNAs: a case study in Arabidopsis. In silico biology 20080101
Disturbances in metabolic, transport and structural genes in experimental colonic inflammation in the rat: a longitudinal genomic analysis. BMC genomics 20080101
Did RNA editing in plant organellar genomes originate under natural selection or through genetic drift? Biology direct 20080101
Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes. Molecular cancer 20080101
Developments in the scientific and clinical understanding of gout. Arthritis research & therapy 20080101
Dramatic down-regulation of oxidoreductases in human hepatocellular carcinoma hepG2 cells: proteomics and gene ontology unveiling new frontiers in cancer enzymology. Proteome science 20080101
Significant association of SREBP-2 genetic polymorphisms with avascular necrosis in the Korean population. BMC medical genetics 20080101
Protein functional surfaces: global shape matching and local spatial alignments of ligand binding sites. BMC structural biology 20080101
Model-guided design of ligand-regulated RNAi for programmable control of gene expression. Molecular systems biology 20080101
Diffusion modeling of ATP signaling suggests a partially regenerative mechanism underlies astrocyte intercellular calcium waves. Frontiers in neuroengineering 20080101
Use of fludarabine-containing chemotherapeutic regimen results in durable complete remission of subcutaneous panniculitis-like T-cell lymphoma. American journal of clinical dermatology 20080101
Non coding extremities of the seven influenza virus type C vRNA segments: effect on transcription and replication by the type C and type A polymerase complexes. Virology journal 20080101
Lesch-Nyhan syndrome: a case report. Journal of the Indian Society of Pedodontics and Preventive Dentistry 20080101
The recently identified P2Y-like receptor GPR17 is a sensor of brain damage and a new target for brain repair. PloS one 20080101
Sequence specificity of BAL 31 nuclease for ssDNA revealed by synthetic oligomer substrates containing homopolymeric guanine tracts. PloS one 20080101
Structures of the signal recognition particle receptor from the archaeon Pyrococcus furiosus: implications for the targeting step at the membrane. PloS one 20080101
Hierarchical structure of cascade of primary and secondary periodicities in Fourier power spectrum of alphoid higher order repeats. BMC bioinformatics 20080101
mtDNA depletion confers specific gene expression profiles in human cells grown in culture and in xenograft. BMC genomics 20080101
Purine metabolism in heart failure: oxidant biology and therapeutic indications. Congestive heart failure (Greenwich, Conn.) 20080101
Guanylyl cyclase sees the light. Journal of biology 20080101
Synthesis of DNA strands site-specifically damaged by c8-arylamine purine adducts and effects on various DNA polymerases. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
A genomic analysis of the archaeal system Ignicoccus hospitalis-Nanoarchaeum equitans. Genome biology 20080101
Treatment of late stage disease in a model of arenaviral hemorrhagic fever: T-705 efficacy and reduced toxicity suggests an alternative to ribavirin. PloS one 20080101
Mycobacterium tuberculosis glucosyl-3-phosphoglycerate synthase: structure of a key enzyme in methylglucose lipopolysaccharide biosynthesis. PloS one 20080101
Architecture of thermal adaptation in an Exiguobacterium sibiricum strain isolated from 3 million year old permafrost: a genome and transcriptome approach. BMC genomics 20080101
Collision induced dissociation studies of alkali metal adducts of tetracyclines and antiviral agents by electrospray ionization, hydrogen/deuterium exchange and multiple stage mass spectrometry. European journal of mass spectrometry (Chichester, England) 20080101
Diets high in selenium and isoflavones decrease androgen-regulated gene expression in healthy rat dorsolateral prostate. Reproductive biology and endocrinology : RB&E 20080101
Prediction of specificity-determining residues for small-molecule kinase inhibitors. BMC bioinformatics 20080101
Recent CR1 non-LTR retrotransposon activity in coscoroba reveals an insertion site preference. BMC genomics 20080101
Genome-wide transcriptional response of an avian pathogenic Escherichia coli (APEC) pst mutant. BMC genomics 20080101
Properties and distribution of pure GA-sequences of mammalian genomes. PloS one 20080101
[Monitoring of nutrition of the population of Chuvashia, in connection with prevalence of ischemic illness of heart]. Voprosy pitaniia 20080101
Aqueous fish extract increases survival in the mouse model of cytostatic toxicity. Journal of experimental & clinical cancer research : CR 20080101
HIV-1 coreceptor usage prediction without multiple alignments: an application of string kernels. Retrovirology 20080101
Assessment of expression of selected Bcl-2 family proteins in lymphoid infiltration in patients with B-cell chronic lymphocytic leukaemia treated with nucleoside analogues. Folia histochemica et cytobiologica 20080101
Macronuclear genome structure of the ciliate Nyctotherus ovalis: single-gene chromosomes and tiny introns. BMC genomics 20080101
Two evolutionarily conserved sequence elements for Peg3/Usp29 transcription. BMC molecular biology 20080101
Small molecules ATP-competitive inhibitors of FLT3: a chemical overview. Current medicinal chemistry 20080101
The role of cytokines in sleep regulation. Current pharmaceutical design 20080101
[Influence of ADP-ribose, AMP and adenosine on bioelectric activity of hibernating ground squirrel atrium and papillary muscle]. Kardiologiia 20080101
Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications. BMC genomics 20080101
Phylogenetic analysis of the non-structural (NS) gene of influenza A viruses isolated from mallards in Northern Europe in 2005. Virology journal 20080101
Acute lung inflammation and ventilator-induced lung injury caused by ATP via the P2Y receptors: an experimental study. Respiratory research 20080101
Prioritizing functional modules mediating genetic perturbations and their phenotypic effects: a global strategy. Genome biology 20080101
DISCLOSE : DISsection of CLusters Obtained by SEries of transcriptome data using functional annotations and putative transcription factor binding sites. BMC bioinformatics 20080101
Evidence from glycine transfer RNA of a frozen accident at the dawn of the genetic code. Biology direct 20080101
Paraneoplastic vasculitis associated with hairy cell leukemia. Prague medical report 20080101
Microarray-based approach identifies microRNAs and their target functional patterns in polycystic kidney disease. BMC genomics 20080101
Arabidopsis eIF2alpha kinase GCN2 is essential for growth in stress conditions and is activated by wounding. BMC plant biology 20080101
Altered ATP release and metabolism in dorsal root ganglia of neuropathic rats. Molecular pain 20080101
Gene expression meta-analysis identifies metastatic pathways and transcription factors in breast cancer. BMC cancer 20080101
The effect of preservation solutions UW and EC on purine concentration in rat kidney. Annales Academiae Medicae Stetinensis 20080101
Antitumor activity of 6-(cyclohexylamino)-1, 3-dimethyl-5(2-pyridyl)furo[2,3-d]pyrimidine-2,4(1H,3H)-dione and Its Ti(IV), Zn(II), Fe(III), and Pd(II) complexes on K562 and Jurkat cell lines. Bioinorganic chemistry and applications 20080101
Purine release: a protective signaling mechanism of the mitochondrial permeability transition pore in ischemia. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20080101
Molecular docking studies on DMDP derivatives as human DHFR inhibitors. Bioinformation 20080101
[Role of acute purine exchange disorders in pathogenesis of metabolism following cryolysis of portal vein]. Voprosy onkologii 20080101
[Purine nucleoside phosphorylase inhibitors and their clinical significance]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20080101
New pathways for alimentary mucositis. Journal of oncology 20080101
Label-free electrical quantification of the dielectrophoretic response of DNA. PMC biophysics 20080101
New data integrating multitargeted antifolates into treatment of first-line and relapsed non-small-cell lung cancer. Clinical lung cancer 20080101
Two- and three-dimensional quantitative structure-activity relationships studies on a series of liver x receptor ligands. The open medicinal chemistry journal 20080101
Butyrate induced cell cycle arrest in bovine cells through targeting gene expression relevant to DNA replication apparatus. Gene regulation and systems biology 20080101
Advances in antisense oligonucleotide development for target identification, validation, and as novel therapeutics. Gene regulation and systems biology 20080101
Using a seed-network to query multiple large-scale gene expression datasets from the developing retina in order to identify and prioritize experimental targets. Bioinformatics and biology insights 20080101
Folate deficiency followed by ionizing radiation perturbs hepatic dihydrofolate reducatse activity. BioFactors (Oxford, England) 20080101
New and emerging trends in the treatment of atopic dermatitis. Patient preference and adherence 20080101
Synthesis and evaluation of L-glutamic Acid analogs as potential anticancer agents. Indian journal of pharmaceutical sciences 20080101
Screwworms, Cochliomyia hominivorax, reared for mass release do not carry and spread foot-and-mouth disease virus and classical swine fever virus. Journal of insect science (Online) 20080101
Modulation of IL-4 level by fludarabine and its relation to apoptosis in chronic B-cell lymphocytic leukemia. The Egyptian journal of immunology 20080101
Doxofyllinium tetra-chloridoanti-monate(III) monohydrate. Acta crystallographica. Section E, Structure reports online 20080101
Ethyl 3-(4-fluoro-phen-yl)-6-methyl-4-oxo-2-(1-cyclohexylamino)-3,4-dihydro-furo[2,3-d]pyrimidine-5-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20080101
7-(1,3-Dioxolan-2-ylmeth-yl)-1,3-di-methyl-purine-2,6(1H,3H)-dione trichloro-acetic acid solvate. Acta crystallographica. Section E, Structure reports online 20080101
Review: mitochondrial defects in breast cancer. Clinical medicine. Oncology 20080101
Recurrent Respiratory Papillomatosis (RRP)-Juvenile Onset. Clinical medicine. Oncology 20080101
Modelling purine derivative excretion in dairy goats: endogenous excretion and the relationship between duodenal input and urinary output. Animal : an international journal of animal bioscience 20080101
Fluorinated alcohol mediated displacement of the C10 acetoxy group of benzo[a]pyrene-7,8,9,10-tetrahydrotetraol tetraacetates: a new route to diol epoxide-deoxyguanosine adducts. The Journal of organic chemistry 20071221
Strand invasion of mixed-sequence B-DNA by acridine-linked, gamma-peptide nucleic acid (gamma-PNA). Journal of the American Chemical Society 20071219
Structure-guided design of AMP mimics that inhibit fructose-1,6-bisphosphatase with high affinity and specificity. Journal of the American Chemical Society 20071219
Sequence-specific oxidative base modifications in hypoxia-inducible genes. Free radical biology & medicine 20071215
Metabolism and elimination of the endogenous DNA adduct, 3-(2-deoxy-beta-D-erythropentofuranosyl)-pyrimido[1,2-alpha]purine-10(3H)-one, in the rat. The Journal of biological chemistry 20071214
The first direct C-H arylation of purine nucleosides. Chemical communications (Cambridge, England) 20071207
Crystal structures of human and murine deoxyribonucleotidases: insights into recognition of substrates and nucleotide analogues. Biochemistry 20071204
Xanthine urolithiasis in a cat: a case report and evaluation of a candidate gene for xanthine dehydrogenase. Journal of feline medicine and surgery 20071201
Key role of uridine kinase and uridine phosphorylase in the homeostatic regulation of purine and pyrimidine salvage in brain. Neurochemistry international 20071201
Acute hypoxia and reoxygenation-induced DNA oxidation in human mononuclear blood cells. Mutation research 20071201
Conformations of flanking bases in HIV-1 RNA DIS kissing complexes studied by molecular dynamics. Biophysical journal 20071201
Tryptophan, adenosine, neurodegeneration and neuroprotection. Metabolic brain disease 20071201
Enzymes as a special class of therapeutic target: clinical drugs and modes of action. Current opinion in structural biology 20071201
Recent progress in the management of chronic lymphocytic leukemia. Cancer treatment reviews 20071201
Towards generating caffeine-free tea by metabolic engineering. Plant foods for human nutrition (Dordrecht, Netherlands) 20071201
A natural antisense transcript of the Petunia hybrida Sho gene suggests a role for an antisense mechanism in cytokinin regulation. The Plant journal : for cell and molecular biology 20071201
Effects of fructose-1,6-diphosphate on endo- and myocardial purine metabolism during coronary artery bypass grafting surgery. The Journal of cardiovascular surgery 20071201
Molecular dynamics simulations and their application to four-stranded DNA. Methods (San Diego, Calif.) 20071201
Mutational analysis of Arabidopsis thaliana plant uncoupling mitochondrial protein. Biochimica et biophysica acta 20071201
The 2,6-disubstituted purine reversine induces growth arrest and polyploidy in human cancer cells. International journal of oncology 20071201
Differential effects of in vitro zinc treatment on gene expression in peripheral blood mononuclear cells derived from young and elderly individuals. Rejuvenation research 20071201
The N-terminal domain of 2',3'-cyclic nucleotide 3'-phosphodiesterase harbors a GTP/ATP binding site. Chemical biology & drug design 20071201
Characterization of the metallocenter of rabbit skeletal muscle AMP deaminase. A new model for substrate interactions at a dinuclear cocatalytic Zn site. Biochimica et biophysica acta 20071201
Synthesis, antimicrobial and antineoplastic activities for agelasine and agelasimine analogs with a beta-cyclocitral derived substituent. Archiv der Pharmazie 20071201
Adenosine-induced complete heart block: not so transient. Emergency medicine Australasia : EMA 20071201
Should TPMT genotype and activity be used to monitor 6-mercaptopurine treatment in children with acute lymphoblastic leukaemia? Journal of clinical pharmacy and therapeutics 20071201
Glycine accumulation is toxic for the cyanobacterium Synechocystis sp. strain PCC 6803, but can be compensated by supplementation with magnesium ions. FEMS microbiology letters 20071201
Infliximab therapy for pediatric Crohn's disease. Expert opinion on biological therapy 20071201
Interaction between mercaptopurine and milk. Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20071201
Characterization of a Giardia lamblia WB C6 clone resistant to the isoflavone formononetin. Microbiology (Reading, England) 20071201
Effect of pharmacological lowering of plasma urate on exercise-induced oxidative stress. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20071201
Nursing guidelines for managing infections in patients with chronic lymphocytic leukemia. Clinical journal of oncology nursing 20071201
Bacterial protein meal in diets for pigs and minks: comparative studies on protein turnover rate and urinary excretion of purine base derivatives. Archives of animal nutrition 20071201
Statistical analysis of effects of testosterone on purine metabolism in rat liver. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20071201
Three new drugs for acute lymphoblastic leukemia: nelarabine, clofarabine, and forodesine. Seminars in oncology 20071201
Mycosis fungoides: pathophysiology and emerging therapies. Seminars in oncology 20071201
Purine nucleoside phosphorylase inhibition as a novel therapeutic approach for B-cell lymphoid malignancies. Seminars in oncology 20071201
Clinical management of T-cell malignancies: current perspectives, key issues, and emerging therapies. Seminars in oncology 20071201
Forodesine treatment and post-transplant graft-versus-host disease in two patients with acute leukemia: facilitation of graft-versus-leukemia effect? Seminars in oncology 20071201
Pharmacology and mechanism of action of forodesine, a T-cell targeted agent. Seminars in oncology 20071201
Therapeutic experience of Bing-Neel Syndrome associated with Waldenstrom's macroglobulinemia. Journal of Korean medical science 20071201
Conserved regulation of MAP kinase expression by PUF RNA-binding proteins. PLoS genetics 20071201
Role of nelarabine in the treatment of T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma. Therapeutics and clinical risk management 20071201
Development of the anti-VEGF aptamer to a therapeutic agent for clinical ophthalmology. Clinical ophthalmology (Auckland, N.Z.) 20071201
Mechanism of direct conversion between C8 adducts and N7 adducts in carcinogenic reactions of arylnitrenium ions with purine nucleosides: a theoretical study. The journal of physical chemistry. B 20071129
Long-range electron and hole transport through DNA with tethered cyclometalated iridium(III) complexes. Journal of the American Chemical Society 20071128
Mutational analysis of the purine riboswitch aptamer domain. Biochemistry 20071120
Novel subsets of the Arabidopsis plasmalemma phosphoproteome identify phosphorylation sites in secondary active transporters. Biochemical and biophysical research communications 20071116
Synthesis, biological activity, and SAR of antimycobacterial 2- and 8-substituted 6-(2-furyl)-9-(p-methoxybenzyl)purines. Bioorganic & medicinal chemistry 20071115
The role of rituximab in combination with pentostatin or cladribine for the treatment of recurrent/refractory hairy cell leukemia. Cancer 20071115
Effect of the Cdk-inhibitor roscovitine on mouse hematopoietic progenitors in vivo and in vitro. Cancer chemotherapy and pharmacology 20071101
Density functional theory studies on tautomeric stability and infrared and Raman spectra of some purine derivatives. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071101
Selective guanosine binding and cytotoxicity of a benzimidazole derived dinickel complex. Journal of inorganic biochemistry 20071101
Characterization of guanine and guanosine transport in primary cultured rat cortical astrocytes and neurons. Glia 20071101
Glutathione-dependent reduction of arsenate by glycogen phosphorylase a reaction coupled to glycogenolysis. Toxicological sciences : an official journal of the Society of Toxicology 20071101
An immunocompetent murine model for oncolysis with an armed and targeted measles virus. Molecular therapy : the journal of the American Society of Gene Therapy 20071101
From ATP to AZD6140: the discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis. Bioorganic & medicinal chemistry letters 20071101
Hypoxanthine decreases equilibrative type of adenosine transport in lymphocytes from Lesch-Nyhan patients. European journal of clinical investigation 20071101
Analysis of virulence and growth of a purine auxotrophic mutant of Xanthomonas oryzae pathovar oryzae. FEMS microbiology letters 20071101
Overexpression of HAM1 gene detoxifies 5-bromodeoxyuridine in the yeast Saccharomyces cerevisiae. Current genetics 20071101
Release of ATP in the central nervous system during systemic inflammation: real-time measurement in the hypothalamus of conscious rabbits. The Journal of physiology 20071101
Risk factors for development of a second lymphoid malignancy in patients with chronic lymphocytic leukaemia. British journal of haematology 20071101
Successful HLA-identical hematopoietic stem cell transplantation in a patient with purine nucleoside phosphorylase deficiency. Pediatric transplantation 20071101
Genetic basis for retention of a critical virulence plasmid of Borrelia burgdorferi. Molecular microbiology 20071101
Partial characterization of the proteome of the mouse striatum. Proteomics 20071101
Examination of the mechanism and energetic contribution of leaving group activation in the purine-specific nucleoside hydrolase from Trypanosoma vivax. Biochimica et biophysica acta 20071101
Purine catabolic enzymes and nitric oxide in patients with recurrent aphthous ulceration. Oral diseases 20071101
Purinergic P2Y2 receptors induce increased MCP-1/CCL2 synthesis and release from rat alveolar and peritoneal macrophages. Journal of immunology (Baltimore, Md. : 1950) 20071101
Nitrogen K-edge XANES - an overview of reference compounds used to identify unknown organic nitrogen in environmental samples. Journal of synchrotron radiation 20071101
Evolving role of monoclonal antibodies in the treatment of chronic lymphocytic leukemia. Expert opinion on investigational drugs 20071101
The GLUT9 gene is associated with serum uric acid levels in Sardinia and Chianti cohorts. PLoS genetics 20071101
tRNASer acceptor stem: conformation and hydration of a microhelix in a crystal structure at 1.8 A resolution. Acta crystallographica. Section D, Biological crystallography 20071101
Unique bisphenol A transcriptome in prostate cancer: novel effects on ERbeta expression that correspond to androgen receptor mutation status. Environmental health perspectives 20071101
[Successful use of cladribine in the treatment of an elderly woman with typical hairy cell leukemia]. Gan to kagaku ryoho. Cancer & chemotherapy 20071101
Processing of nuclear viroids in vivo: an interplay between RNA conformations. PLoS pathogens 20071101
Nucleobase analogs for degenerate hybridization devised through conformational pairing analysis. BioTechniques 20071101
[Chromatographic behavior of purine derivatives on cucurbit [6] uril monorotaxane-bonded silica stationary phase by high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20071101
Antero-ventral internal pallidum stimulation improves behavioral disorders in Lesch-Nyhan disease. Movement disorders : official journal of the Movement Disorder Society 20071031
Rpn10p is a receptor for ubiquitinated Gcn4p in proteasomal proteolysis. Molecules and cells 20071031
Anopheles gambiae purine nucleoside phosphorylase: catalysis, structure, and inhibition. Biochemistry 20071030
Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue. FEBS letters 20071030
On the origin of biochemistry at an alkaline hydrothermal vent. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20071029
Identification and biochemical characterization of unique secretory nucleases of the human enteric pathogen, Entamoeba histolytica. The Journal of biological chemistry 20071026
A novel strategy to assemble the beta-diketo acid pharmacophore of HIV integrase inhibitors on purine nucleobase scaffolds. The Journal of organic chemistry 20071026
Purine-mediated signalling triggers eye development. Nature 20071025
Pemetrexed pharmacokinetics and pharmacodynamics in a phase I/II study of doublet chemotherapy with vinorelbine: implications for further optimisation of pemetrexed schedules. British journal of cancer 20071022
Episomally driven antisense mRNA abrogates the hyperinducible expression and function of a unique cell surface class I nuclease in the primitive trypanosomatid parasite, Crithidia luciliae. Journal of molecular biology 20071019
Ribavirin: analytical determinations since the origin until today. Journal of pharmaceutical and biomedical analysis 20071018
Non-hematopoietic stem cell transplantation treatment of juvenile myelomonocytic leukemia: a retrospective analysis and definition of response criteria. Pediatric blood & cancer 20071015
Four-stranded coordination helices containing silver-adenine (purine) metallaquartets. Inorganic chemistry 20071015
Purinergic modulation of glutamate release under ischemic-like conditions in the hippocampus. Neuroscience 20071012
Synthesis of nucleotide analogues by a promiscuous phosphoribosyltransferase. Organic letters 20071011
Spectroscopic and theoretical insights into sequence effects of aminofluorene-induced conformational heterogeneity and nucleotide excision repair. Biochemistry 20071009
Drugging the cancer chaperone HSP90: combinatorial therapeutic exploitation of oncogene addiction and tumor stress. Annals of the New York Academy of Sciences 20071001
The identification of (3R,4S)-5-fluoro-5-deoxy-D-ribulose-1-phosphate as an intermediate in fluorometabolite biosynthesis in Streptomyces cattleya. Bioorganic chemistry 20071001
Lymphoma risk in inflammatory bowel disease: is it the disease or its treatment? Inflammatory bowel diseases 20071001
Specific type of interactions in the quaternary system of Cu(II), adenosine 5'-triphosphate, 1,11-diamino-4,8-diazaundecane and uridine. Journal of inorganic biochemistry 20071001
Conditional overexpression of Stat3alpha in differentiating myeloid cells results in neutrophil expansion and induces a distinct, antiapoptotic and pro-oncogenic gene expression pattern. Journal of leukocyte biology 20071001
Mammalian mismatches in nucleotide metabolism: implications for xenotransplantation. Molecular and cellular biochemistry 20071001
A method for quantification of nucleotides and nucleotide analogues in thymidine kinase assays using lanthanum phosphate coprecipitation. Analytical biochemistry 20071001
The tolerance to exchanges of the Watson Crick base pair in the hammerhead ribozyme core is determined by surrounding elements. RNA (New York, N.Y.) 20071001
Determination of serum uric acid using high-performance liquid chromatography (HPLC)/isotope dilution mass spectrometry (ID-MS) as a candidate reference method. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071001
Adenosine inhibition of lipopolysaccharide-induced interleukin-6 secretion by the osteoblastic cell line MG-63. Calcified tissue international 20071001
Characterization of the adenine nucleoside specific phosphorylase of Bacillus cereus. Biochimica et biophysica acta 20071001
Clofarabine: past, present, and future. Leukemia & lymphoma 20071001
Binding isotope effects: boon and bane. Current opinion in chemical biology 20071001
The RNAi-mediated silencing of xanthine dehydrogenase impairs growth and fertility and accelerates leaf senescence in transgenic Arabidopsis plants. Plant & cell physiology 20071001
Corticosteroid-dependent eosinophilic oesophagitis: azathioprine and 6-mercaptopurine can induce and maintain long-term remission. European journal of gastroenterology & hepatology 20071001
Characterization of N-deoxyribosyltransferase from Lactococcus lactis subsp. lactis. Biochimica et biophysica acta 20071001
Structure of the nondiscriminating aspartyl-tRNA synthetase from the crenarchaeon Sulfolobus tokodaii strain 7 reveals the recognition mechanism for two different tRNA anticodons. Acta crystallographica. Section D, Biological crystallography 20071001
Antiviral effects of PNA in duck hepatitis B virus infection model. Acta pharmacologica Sinica 20071001
The use of beta-D-2,6-diaminopurine dioxolane with or without mycophenolate mofetil in drug-resistant HIV infection. AIDS (London, England) 20071001
Primary chronic cold agglutinin disease: an update on pathogenesis, clinical features and therapy. Hematology (Amsterdam, Netherlands) 20071001
Enhanced mutagenesis of Salmonella tester strains due to deletion of genes other than uvrB. Environmental and molecular mutagenesis 20071001
Nicotinamide riboside kinase structures reveal new pathways to NAD+. PLoS biology 20071001
The natural history of fludarabine-refractory chronic lymphocytic leukemia patients who fail alemtuzumab or have bulky lymphadenopathy. Leukemia & lymphoma 20071001
Universally sloppy parameter sensitivities in systems biology models. PLoS computational biology 20071001
Metabolic reconstruction and modeling of nitrogen fixation in Rhizobium etli. PLoS computational biology 20071001
Identification of gene markers for formaldehyde exposure in humans. Environmental health perspectives 20071001
Genome sequence of Babesia bovis and comparative analysis of apicomplexan hemoprotozoa. PLoS pathogens 20071001
Isolation and functional analysis of sulfite oxidase gene AtSO promoter from Arabidopsis thaliana. Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20071001
Autologous stem cell transplantation for chronic lymphocytic leukemia. Seminars in hematology 20071001
Mechanism-of-action determination of GMP synthase inhibitors and target validation in Candida albicans and Aspergillus fumigatus. Chemistry & biology 20071001
The epigenetics of mantle cell lymphoma. Current treatment options in oncology 20071001
Oblimersen for the treatment of patients with chronic lymphocytic leukemia. Therapeutics and clinical risk management 20071001
Glutamine phosphoribosylpyrophosphate amidotransferase-independent phosphoribosyl amine synthesis from ribose 5-phosphate and glutamine or asparagine. The Journal of biological chemistry 20070928
13C-enrichment at carbons 8 and 2 of uric acid after 13C-labeled folate dose in man. Biochemical and biophysical research communications 20070921
Determination of purine and pyrimidine bases in natural and cultured Cordyceps using optimum acid hydrolysis followed by high performance liquid chromatography. Journal of pharmaceutical and biomedical analysis 20070921
Inhibition of Mycobacterium tuberculosis, Mycobacterium bovis, and Mycobacterium avium by novel dideoxy nucleosides. Journal of medicinal chemistry 20070920
Treatment-related myelodysplastic syndrome and acute myelogenous leukemia in patients treated with ibritumomab tiuxetan radioimmunotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070920
High resolution crystal structures of Mycobacterium tuberculosis adenosine kinase: insights into the mechanism and specificity of this novel prokaryotic enzyme. The Journal of biological chemistry 20070914
Synthesis of oxepane ring containing monocyclic, conformationally restricted bicyclic and spirocyclic nucleosides from D-glucose: a cycloaddition approach. The Journal of organic chemistry 20070914
Role of A(2A) adenosine receptors in regulation of opsonized E. coli-induced macrophage function. Purinergic signalling 20070905
[Recurrent urinary lithiasis revealing hereditary xanthinuria]. Presse medicale (Paris, France : 1983) 20070901
The extracellular cardiac purine metabolome in sepsis. Shock (Augusta, Ga.) 20070901
Synthesis and anti-HIV activity of (-)-beta-D-(2R,4R)-1,3-dioxolane-2,6-diamino purine (DAPD) (amdoxovir) and (-)-beta-D-(2R,4R)-1,3-dioxolane guanosine (DXG) prodrugs. Antiviral research 20070901
Drosophila deoxyribonucleoside kinase mutants with enhanced ability to phosphorylate purine analogs. Gene therapy 20070901
Genetic removal of the A2A adenosine receptor enhances pulmonary inflammation, mucin production, and angiogenesis in adenosine deaminase-deficient mice. American journal of physiology. Lung cellular and molecular physiology 20070901
Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast. FEMS yeast research 20070901
Cyclin-dependent kinase inhibitors block erythrocyte invasion and intraerythrocytic development of Babesia bovis in vitro. Parasitology 20070901
Complete (1)H and (13)C NMR spectral assignment of alpha- and beta-adenosine, 2'-deoxyadenosine and their acetate derivatives. Magnetic resonance in chemistry : MRC 20070901
Waldenström macroglobulinaemia. British journal of haematology 20070901
Identification of a mitotic recombination hotspot on chromosome III of the asexual fungus Aspergillus niger and its possible correlation with [corrected] elevated basal transcription. Current genetics 20070901
Efficacy and safety of allopurinol in patients with hypoxanthine-guanine phosphoribosyltransferase deficiency. Metabolism: clinical and experimental 20070901
Arts syndrome is caused by loss-of-function mutations in PRPS1. American journal of human genetics 20070901
Mutations in PRPS1, which encodes the phosphoribosyl pyrophosphate synthetase enzyme critical for nucleotide biosynthesis, cause hereditary peripheral neuropathy with hearing loss and optic neuropathy (cmtx5). American journal of human genetics 20070901
The role of DNA repair in chronic lymphocytic leukemia pathogenesis and chemotherapy resistance. Current oncology reports 20070901
Chemoimmunotherapy of chronic lymphocytic leukemia. Best practice & research. Clinical haematology 20070901
The role of stem-cell transplantation in chronic lymphocytic leukemia risk-adapted therapy. Best practice & research. Clinical haematology 20070901
Fatal Epstein-Barr virus-associated lymphoproliferative disorder following treatment with a novel mTOR inhibitor for relapsed chronic lymphocytic leukemia leukemia cells. Haematologica 20070901
A structure-based flexible search method for motifs in RNA. Journal of computational biology : a journal of computational molecular cell biology 20070901
Orthologous transcription factors in bacteria have different functions and regulate different genes. PLoS computational biology 20070901
Irf3 polymorphism alters induction of interferon beta in response to Listeria monocytogenes infection. PLoS genetics 20070901
Structure-templated predictions of novel protein interactions from sequence information. PLoS computational biology 20070901
Forodesine (BCX-1777, Immucillin H)--a new purine nucleoside analogue: mechanism of action and potential clinical application. Mini reviews in medicinal chemistry 20070901
Adenosine deaminase activity in cats infected with feline immunodeficiency virus. The Journal of veterinary medical science 20070901
Cannabinoid receptors expression in bone marrow trephine biopsy of chronic lymphocytic leukaemia patients treated with purine analogues. Experimental oncology 20070901
Nelarabine: a novel purine antimetabolite antineoplastic agent. Clinical therapeutics 20070901
[Differential gene expression profile in seasonal allergic rhinitis with and without asthma]. Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20070901
Second Joint Italian-German Purine Club Meeting: 'Progress in purinergic receptor pharmacology and function'. Purinergic signalling 20070901
Structural and functional evolution of the P2Y(12)-like receptor group. Purinergic signalling 20070901
P2 receptor-mediated modulation of neurotransmitter release-an update. Purinergic signalling 20070901
Adenosine A(1) receptor: Functional receptor-receptor interactions in the brain. Purinergic signalling 20070901
The role of ATP and adenosine in the brain under normoxic and ischemic conditions. Purinergic signalling 20070901
Modification of neuropathic pain sensation through microglial ATP receptors. Purinergic signalling 20070901
New insights into purinergic receptor signaling in neuronal differentiation, neuroprotection, and brain disorders. Purinergic signalling 20070901
[(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions. Purinergic signalling 20070901
MPP(+)-induced cytotoxicity in neuroblastoma cells: Antagonism and reversal by guanosine. Purinergic signalling 20070901
Guanosine reduces apoptosis and inflammation associated with restoration of function in rats with acute spinal cord injury. Purinergic signalling 20070901
Novel N7- and N1-substituted cGMP derivatives are potent activators of cyclic nucleotide-gated channels. Journal of medicinal chemistry 20070823
Selective liquid CO2 extraction of purine alkaloids in different Ilex paraguariensis progenies grown under environmental influences. Journal of agricultural and food chemistry 20070822
Mapping ligand interactions with the hyperpolarization activated cyclic nucleotide modulated (HCN) ion channel binding domain using a soluble construct. Biochemistry 20070821
Acidity and proton affinity of hypoxanthine in the gas phase versus in solution: intrinsic reactivity and biological implications. The Journal of organic chemistry 20070817
Virologic characterization of HIV type 1 with a codon 70 deletion in reverse transcriptase. Journal of acquired immune deficiency syndromes (1999) 20070815
Anti-malarial activity of N6-modified purine analogues. Bioorganic & medicinal chemistry 20070815
Effects of organosulfurs, isothiocyanates and vitamin C towards hydrogen peroxide-induced oxidative DNA damage (strand breaks and oxidized purines/pyrimidines) in human hepatoma cells. Chemico-biological interactions 20070815
Indomethacin stimulates activity and expression of ecto-5'-nucleotidase/CD73 in glioma cell lines. European journal of pharmacology 20070813
Structural and functional basis for (S)-allantoin formation in the ureide pathway. The Journal of biological chemistry 20070810
CH/pi interactions in DNA and proteins. A theoretical study. The journal of physical chemistry. B 20070809
hTERT-targeted E. coli purine nucleoside phosphorylase gene/6-methylpurine deoxyribose therapy for pancreatic cancer. Chinese medical journal 20070805
P-BOSS: a new filtering method for treasure hunting in metabolomics. Journal of chromatography. A 20070803
Fluorinated alcohol mediated control over cis vs trans opening of benzo[a]pyrene-7,8-diol 9,10-epoxides at C-10 by the exocyclic amino groups of O6-allyl protected deoxyguanosine and of deoxyadenosine. The Journal of organic chemistry 20070803
Polymorphisms in folate, pyrimidine, and purine metabolism are associated with efficacy and toxicity of methotrexate in psoriasis. The Journal of investigative dermatology 20070801
Role of CNT3 in the transepithelial flux of nucleosides and nucleoside-derived drugs. The Journal of physiology 20070801
The anti-schistosomal drug praziquantel is an adenosine antagonist. Parasitology 20070801
Hepatosplenic T-cell lymphoma in adolescents and young adults with Crohn's disease: a cautionary tale? Inflammatory bowel diseases 20070801
Tissue-specific aberrations of gene expression in HPRT-deficient mice: functional complexity in a monogenic disease? Molecular therapy : the journal of the American Society of Gene Therapy 20070801
Replication-associated purine asymmetry may contribute to strand-biased gene distribution. Genomics 20070801
Synthesis and biological evaluation of 9-deazaguanine derivatives connected by a linker to difluoromethylene phosphonic acid as multi-substrate analogue inhibitors of PNP. Bioorganic & medicinal chemistry letters 20070801
Molecules targeting the purine salvage pathway in Apicomplexan parasites. Trends in parasitology 20070801
Phosphoproteomic analysis of neuronal cell death by glutamate-induced oxidative stress. Proteomics 20070801
Effects of feeding fat-coated butyrate on mucosal morphology and function in the small intestine of the pig. Journal of animal physiology and animal nutrition 20070801
The role of mitochondria in protection of the heart by preconditioning. Biochimica et biophysica acta 20070801
Development of a liquid chromatography-electrospray ionization tandem mass spectrometry method for detecting oxaliplatin-DNA intrastrand cross-links in biological samples. Chemical research in toxicology 20070801
Morphine enhances purine nucleotide catabolism in vivo and in vitro. Acta pharmacologica Sinica 20070801
Severe pulmonary toxicity after azathioprine/6-mercaptopurine initiation for the treatment of inflammatory bowel disease. Journal of clinical gastroenterology 20070801
Co-localization and functional cross-talk between A1 and P2Y1 purine receptors in rat hippocampus. The European journal of neuroscience 20070801
Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase. PLoS biology 20070801
Novel protease and polymerase inhibitors for the treatment of hepatitis C virus infection. Expert opinion on investigational drugs 20070801
Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria. PLoS genetics 20070801
Origin of informational polymers and the search for non-terran life: protection of the polymeric state of DNA by phosphate minerals. Astrobiology 20070801
Changes in serum adenosine deaminase activity during normal pregnancy. Journal of Korean medical science 20070801
The role of hematopoietic stem cell transplantation in Chronic Lymphocytic Leukemia. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20070801
Oxidatively damaged DNA and inflammation in the liver of dyslipidemic ApoE-/- mice exposed to diesel exhaust particles. Toxicology 20070731
Phosphonated carbocyclic 2'-oxa-3'-azanucleosides as new antiretroviral agents. Journal of medicinal chemistry 20070726
Mechanism of deactivation of triplet-excited riboflavin by ascorbate, carotenoids, and tocopherols in homogeneous and heterogeneous aqueous food model systems. Journal of agricultural and food chemistry 20070725
Nonpolar isosteres of damaged DNA bases: effective mimicry of mutagenic properties of 8-oxopurines. Journal of the American Chemical Society 20070718
Fludarabine-mediated suppression of the excision repair enzyme ERCC1 contributes to the cytotoxic synergy with the DNA minor groove crosslinking agent SJG-136 (NSC 694501) in chronic lymphocytic leukaemia cells. British journal of cancer 20070716
Use of pathway analysis and genome context methods for functional genomics of Mycoplasma pneumoniae nucleotide metabolism. Gene 20070715
N9-benzyl-substituted 1,3-dimethyl- and 1,3-dipropyl-pyrimido[2,1-f]purinediones: synthesis and structure-activity relationships at adenosine A1 and A2A receptors. Bioorganic & medicinal chemistry 20070715
Substrate overlap between Mrp4 and Abcg2/Bcrp affects purine analogue drug cytotoxicity and tissue distribution. Cancer research 20070715
Photoreaction at 5'-(G/C)AA(Br)UT-3' sequence in duplex DNA: efficient generation of uracil-5-yl radical by charge transfer. Journal of the American Chemical Society 20070704
Amino acid residues of Leishmania donovani cyclophilin key to interaction with its adenosine kinase: biological implications. Biochemistry 20070703
Adenosine ecto-deaminase (ecto-ADA) from porcine cerebral cortex synaptic membrane. Brain research 20070702
Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends. Medicinal research reviews 20070701
Molecular modeling of purinergic receptor P2Y12 and interaction with its antagonists. Journal of molecular graphics & modelling 20070701
Differential physiological and developmental expression of the UapA and AzgA purine transporters in Aspergillus nidulans. Fungal genetics and biology : FG & B 20070701
Pathway analysis identifies perturbation of genetic networks induced by butyrate in a bovine kidney epithelial cell line. Functional & integrative genomics 20070701
Heavy water labeling method for measuring the effect of genistein on mammary gland carcinogenesis. Molecular and cellular biochemistry 20070701
Transcriptome profile of dendritic cells during malaria: cAMP regulation of IL-6. Cellular microbiology 20070701
Gene expression and characterization of 2-keto-3-deoxygluconate kinase, a key enzyme in the modified Entner-Doudoroff pathway of the aerobic and acidophilic hyperthermophile Sulfolobus tokodaii. Protein expression and purification 20070701
Complete mitochondrial genome of the bullhead torrent catfish, Liobagrus obesus (Siluriformes, Amblycipididae): Genome description and phylogenetic considerations inferred from the Cyt b and 16S rRNA genes. Gene 20070701
Control of basal extracellular adenosine concentration in rat cerebellum. The Journal of physiology 20070701
Spreading dilatation to luminal perfusion of ATP and UTP in rat isolated small mesenteric arteries. The Journal of physiology 20070701
Arginine (CGC) codon targeting in the human prostacyclin receptor gene (PTGIR) and G-protein coupled receptors (GPCR). Gene 20070701
Role of the stage-regulated nucleoside transporter TbNT10 in differentiation and adenosine uptake in Trypanosoma brucei. Molecular and biochemical parasitology 20070701
1H and 13C NMR study of the complex formed by copper(II) with the nucleoside antibiotic sinefungin. Journal of inorganic biochemistry 20070701
Chemical genetic identification of glutamine phosphoribosylpyrophosphate amidotransferase as the target for a novel bleaching herbicide in Arabidopsis. Plant physiology 20070701
Novel algorithms reveal streptococcal transcriptomes and clues about undefined genes. PLoS computational biology 20070701
Update on front-line therapy for follicular lymphoma: chemo-immunotherapy with rituximab and survival. Expert review of anticancer therapy 20070701
Divergent evolution of human p53 binding sites: cell cycle versus apoptosis. PLoS genetics 20070701
Pemetrexed and oxaliplatin for metastatic colorectal cancer: results of a phase I Mayo Cancer Center Research Consortium trial, MC0248. Clinical colorectal cancer 20070701
A brief primer on treatments of cutaneous T cell lymphoma, newly approved or late in development. Journal of drugs in dermatology : JDD 20070701
From purines to basic biochemical concepts: Experiments for high school students. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 20070701
A quinoxaline 1,4-di-N-oxide derivative induces DNA oxidative damage not attenuated by vitamin C and E treatment. Chemico-biological interactions 20070630
New platinum(II) complexes containing both an O,O'-chelated acetylacetonate ligand and a sulfur ligand in the platinum coordination sphere induce apoptosis in HeLa cervical carcinoma cells. Biochemical pharmacology 20070630
Electron transfer between guanosine radical and amino acids in aqueous solution. 1. Reduction of guanosine radical by tyrosine. The journal of physical chemistry. B 20070628
Simultaneous analysis of catechins, gallic acid, strictinin, and purine alkaloids in green tea by using catechol as an internal standard. Journal of agricultural and food chemistry 20070627
Transition-state variation in human, bovine, and Plasmodium falciparum adenosine deaminases. Journal of the American Chemical Society 20070627
Mitsunobu coupling of nucleobases and alcohols: an efficient, practical synthesis for novel nonsugar carbon nucleosides. The Journal of organic chemistry 20070622
Efficient syntheses of C(8)-aryl adducts of adenine and guanine formed by reaction of radical cation metabolites of carcinogenic polycyclic aromatic hydrocarbons with DNA. The Journal of organic chemistry 20070622
Complex retention behavior of pyrimidines on biomembrane-mimic immobilized-artificial-membrane phase. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615
The identification of similarities between biological networks: application to the metabolome and interactome. Journal of molecular biology 20070615
Complementation of the oxidatively damaged DNA repair defect in Cockayne syndrome A and B cells by Escherichia coli formamidopyrimidine DNA glycosylase. Free radical biology & medicine 20070615
Computational clues for a new mechanism in the glycosylase activity of the human DNA repair protein hOGG1. A generalized paradigm for purine-repairing systems? The journal of physical chemistry. B 20070614
Complex changes in ecto-nucleoside 5'-triphosphate diphosphohydrolase expression in hypoxanthine phosphoribosyl transferase deficiency. Neuroscience letters 20070608
Understanding the isomerization of the HIV-1 dimerization initiation domain by the nucleocapsid protein. Journal of molecular biology 20070608
Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice. Oncogene 20070607
Acyclic ribooxacarbenium ion mimics as transition state analogues of human and malarial purine nucleoside phosphorylases. Journal of the American Chemical Society 20070606
Hairy cell leukaemia complicated by anti-MAG paraproteinemic demyelinating neuropathy: resolution of neurological syndrome after cladribrine treatment. Leukemia research 20070601
Simultaneous determination of a selective adenosine 2A agonist, BMS-068645, and its acid metabolite in human plasma by liquid chromatography-tandem mass spectrometry--evaluation of the esterase inhibitor, diisopropyl fluorophosphate, in the stabilization of a labile ester-containing drug. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601
Auto-inhibition of rat parallel fibre-Purkinje cell synapses by activity-dependent adenosine release. The Journal of physiology 20070601
Human DEAD-box ATPase DDX3 shows a relaxed nucleoside substrate specificity. Proteins 20070601
Purine and pyrimidine receptors. Cellular and molecular life sciences : CMLS 20070601
Methotrexate and erythro-9-(2-hydroxynon-3-yl) adenine therapy for rat adjuvant arthritis and the effect of methotrexate on in vivo purine metabolism. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070601
A new method for the construction of a mutant library with a predictable occurrence rate using Poisson distribution. Journal of microbiological methods 20070601
Fabrication and characterization of open-tubular CEC modified with tentacle-type metal-chelating polymer chains. Electrophoresis 20070601
Temporal and mechanistic dissociation of ATP and adenosine release during ischaemia in the mammalian hippocampus. Journal of neurochemistry 20070601
Quantitative proteomic comparison of mouse peroxisomes from liver and kidney. Proteomics 20070601
Adenosine closes the K+ channel KCa3.1 in human lung mast cells and inhibits their migration via the adenosine A2A receptor. European journal of immunology 20070601
Efficient electrogene therapy for pancreatic adenocarcinoma treatment using the bacterial purine nucleoside phosphorylase suicide gene with fludarabine. International journal of oncology 20070601
Nucleobase-dependent reactivity of a quinone metabolite of pentachlorophenol. Chemical research in toxicology 20070601
Therapeutic issues in HIV/HCV-coinfected patients. Journal of viral hepatitis 20070601
Characterization of adducts formed in the reaction of glutaraldehyde with 2'-deoxyadenosine. Chemical research in toxicology 20070601
Suppressive effect of culture supernatant of erythrocytes and serum from dogs infected with Babesia gibsoni on the morphological maturation of canine reticulocytes in vitro. Journal of veterinary science 20070601
Uric acid changes in urine and plasma: an effective tool in screening for purine inborn errors of metabolism and other pathological conditions. Journal of inherited metabolic disease 20070601
A clinical pharmacogenetic model to predict the efficacy of methotrexate monotherapy in recent-onset rheumatoid arthritis. Arthritis and rheumatism 20070601
Legumes symbioses: absence of Nod genes in photosynthetic bradyrhizobia. Science (New York, N.Y.) 20070601
The effect of local nucleotides on synonymous codon usage in the honeybee (Apis mellifera L.) genome. Journal of molecular evolution 20070601
Molecular genetic analysis of purine nucleobase transport in Leishmania major. Molecular microbiology 20070601
The critical role of the linear plasmid lp36 in the infectious cycle of Borrelia burgdorferi. Molecular microbiology 20070601
Purine and cytokine concentrations in the renal vein of the allograft during reperfusion. Transplantation proceedings 20070601
Alemtuzumab in chronic lymphocytic leukemia. Current oncology (Toronto, Ont.) 20070601
Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans. PLoS pathogens 20070601
Adenine synthesis in interstellar space: mechanisms of prebiotic pyrimidine-ring formation of monocyclic HCN-pentamers. Astrobiology 20070601
Purine nucleoside phosphorylase deficiency in a patient with spastic paraplegia and recurrent infections. Journal of child neurology 20070601
Equine metabolic myopathies with emphasis on the diagnostic approach. Comparison with human myopathies. A review. The Veterinary quarterly 20070601
Aminohydrolases acting on adenine, adenosine and their derivatives. Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20070601
Sustained release of acyclovir from nano-liposomes and nano-niosomes: an in vitro study. International journal of nanomedicine 20070601
Strong and weak hydrogen bonds in drug-DNA complexes: a statistical analysis. Journal of biosciences 20070601
Role of P2 purinergic receptors in synaptic transmission under normoxic and ischaemic conditions in the CA1 region of rat hippocampal slices. Purinergic signalling 20070601
Ecto-5'-nucleotidase and intestinal ion secretion by enteropathogenic Escherichia coli. Purinergic signalling 20070601
Mechanisms of over-activated innate immune system regulation in autoimmune and neurodegenerative disorders. Neuropsychiatric disease and treatment 20070601
Synthesis of 5'-methylthio coformycins: specific inhibitors for malarial adenosine deaminase. Journal of the American Chemical Society 20070530
Determination of redox potentials for the Watson-Crick base pairs, DNA nucleosides, and relevant nucleoside analogues. The journal of physical chemistry. B 20070517
Synthesis, biological evaluation and molecular modeling studies of N6-benzyladenosine analogues as potential anti-toxoplasma agents. Biochemical pharmacology 20070515
TOR-induced resistance to toxic adenosine analogs in Leishmania brought about by the internalization and degradation of the adenosine permease. Experimental cell research 20070515
S(N)Ar displacements with 6-(fluoro, chloro, bromo, iodo, and alkylsulfonyl)purine nucleosides: synthesis, kinetics, and mechanism1. Journal of the American Chemical Society 20070509
Purification and characterization of the FeII- and alpha-ketoglutarate-dependent xanthine hydroxylase from Aspergillus nidulans. Biochemistry 20070508
Synthesis, biological testing, and binding mode prediction of 6,9-diarylpurin-8-ones as p38 MAP kinase inhibitors. Journal of medicinal chemistry 20070503
Allantoin has a limited role as nitrogen source in cultured coffee cells. Journal of plant physiology 20070501
Role of roscovitine and IBMX on kinetics of nuclear and cytoplasmic maturation of bovine oocytes in vitro. Animal reproduction science 20070501
Global analysis of community-associated methicillin-resistant Staphylococcus aureus exoproteins reveals molecules produced in vitro and during infection. Cellular microbiology 20070501
Evidence of a species complex within the food-borne trematode Opisthorchis viverrini and possible co-evolution with their first intermediate hosts. International journal for parasitology 20070501
A model for triplet mutation formation based on error-prone translesional DNA synthesis opposite UV photolesions. DNA repair 20070501
Management options for adenosine deaminase deficiency; proceedings of the EBMT satellite workshop (Hamburg, March 2006). Clinical immunology (Orlando, Fla.) 20070501
Interguanine hydrogen-bonding patterns in adducts with water and Zn-purine complexes (purine is 9-methyladenine and 9-methylguanine). Unexpected preference of Zn(II) for adenine-N7 over guanine-N7. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070501
Fludarabine induces apoptosis of human T-cell leukemia virus type 1-infected T cells via inhibition of the nuclear factor-kappaB signal pathway. Leukemia 20070501
Evidence that ATP or a related purine is an excitatory neurotransmitter in the longitudinal muscle of mouse distal colon. British journal of pharmacology 20070501
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Molecular genetics and metabolism 20070501
Pyrimidine transport activities in trypanosomes. Trends in parasitology 20070501
Basal ganglia dopamine loss due to defect in purine recycling. Neurobiology of disease 20070501
Neighboring group participation in the transition state of human purine nucleoside phosphorylase. Biochemistry 20070501
Biochemical and structural characterization of mammalian-like purine nucleoside phosphorylase from the Archaeon Pyrococcus furiosus. The FEBS journal 20070501
Successful cardiac transplantation in Barth syndrome--single-centre experience of four patients. Pediatric transplantation 20070501
13C enrichment of carbons 2 and 8 of purine by folate-dependent reactions after [13C]formate and [2-13C]glycine dosing in adult humans. Metabolism: clinical and experimental 20070501
Nitric oxide generation is associated with an unbalance of protein tyrosine phosphatases during liver transplantation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20070501
Mouse equilibrative nucleoside transporter 2 (mENT2) transports nucleosides and purine nucleobases differing from human and rat ENT2. Biological & pharmaceutical bulletin 20070501
2-Chloro-6-(2-furyl)-9-(4-methoxybenzyl)-9H-purine. Acta crystallographica. Section C, Crystal structure communications 20070501
Z-DNA, an active element in the genome. Frontiers in bioscience : a journal and virtual library 20070501
Skin lesions in chronic lymphocytic leukemia. Leukemia & lymphoma 20070501
Fluorescence-based adenylyl cyclase assay adaptable to high throughput screening. Combinatorial chemistry & high throughput screening 20070501
RNA interference tolerates 2'-fluoro modifications at the Argonaute2 cleavage site. Chemistry & biodiversity 20070501
Tenofovir disoproxil fumarate for prevention of HIV infection in women: a phase 2, double-blind, randomized, placebo-controlled trial. PLoS clinical trials 20070501
Structure-based design, synthesis, evaluation, and crystal structures of transition state analogue inhibitors of inosine monophosphate cyclohydrolase. The Journal of biological chemistry 20070427
The role of arginine 310 in catalysis and substrate specificity in xanthine dehydrogenase from Rhodobacter capsulatus. The Journal of biological chemistry 20070427
Structural analysis of a ternary complex of allantoate amidohydrolase from Escherichia coli reveals its mechanics. Journal of molecular biology 20070427
Phase I trial and pharmacokinetic study of pemetrexed in children with refractory solid tumors: the Children's Oncology Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070420
PRODAN-conjugated DNA: synthesis and photochemical properties. Journal of the American Chemical Society 20070418
Synthesis and biological evaluation of two glycerolipidic prodrugs of didanosine for direct lymphatic delivery against HIV. Bioorganic & medicinal chemistry letters 20070415
The case for 8,5'-cyclopurine-2'-deoxynucleosides as endogenous DNA lesions that cause neurodegeneration in xeroderma pigmentosum. Neuroscience 20070414
Characterization of DNA--protein cross-links induced by oxanine: cellular damage derived from nitric oxide and nitrous acid. Biochemistry 20070403
Mode of action of natural and synthetic drugs against Trypanosoma cruzi and their interaction with the mammalian host. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20070401
Correlation of ZAP-70 expression in B cell leukemias to the ex vivo response to a combination of fludarabine/genistein. Cancer immunology, immunotherapy : CII 20070401
Prebiotic microreactors: a synthesis of purines and dihydroxy compounds in aqueous aerosol. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20070401
Biochemical and pharmacological characterization of P-site inhibitors on homodimeric guanylyl cyclase domain from natriuretic peptide receptor-A. Biochemical pharmacology 20070401
The HIV-1 central DNA flap region contains a 'flapping' third strand. Biophysical chemistry 20070401
Structure of the d(CGCGAATTCGCG)2 complex of the minor groove binding alkylating agent alkamin studied by mass spectrometry. Molecular pharmacology 20070401
Oxidative damage in nucleic acids and Parkinson's disease. Journal of neuroscience research 20070401
Human xanthine oxidase changes its substrate specificity to aldehyde oxidase type upon mutation of amino acid residues in the active site: roles of active site residues in binding and activation of purine substrate. Journal of biochemistry 20070401
Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts. Leukemia 20070401
Allopurinol as adjunctive therapy in intractable epilepsy: a double-blind and placebo-controlled trial. Archives of medical research 20070401
Synthesis of some novel substituted purine derivatives as potential anticancer, anti-HIV-1 and antimicrobial agents. Archiv der Pharmazie 20070401
Effects of sucrose on plasma concentrations and urinary excretion of purine bases. Metabolism: clinical and experimental 20070401
Radiosensitization by nitric oxide at low radiation doses. Radiation research 20070401
Current treatment options in prolymphocytic leukemia. Medical science monitor : international medical journal of experimental and clinical research 20070401
M. tuberculosis Ser/Thr protein kinase D phosphorylates an anti-anti-sigma factor homolog. PLoS pathogens 20070401
Rev proteins of human and simian immunodeficiency virus enhance RNA encapsidation. PLoS pathogens 20070401
Preparation of guanine and diaminopurine from biuret. Part III. Chemistry & biodiversity 20070401
Allogeneic stem cell transplantation for patients with advanced hematological malignancies: comparison of fludarabine-based reduced intensity conditioning versus myeloablative conditioning. Journal of Korean medical science 20070401
Hormesis and its place in nonmonotonic dose-response relationships: some scientific reality checks. Environmental health perspectives 20070401
A novel variant L263F in human inosine 5'-monophosphate dehydrogenase 2 is associated with diminished enzyme activity. Pharmacogenetics and genomics 20070401
Community-based phase II trial of pentostatin, cyclophosphamide, and rituximab (PCR) biochemotherapy in chronic lymphocytic leukemia and small lymphocytic lymphoma. Cancer biotherapy & radiopharmaceuticals 20070401
Treatment of Waldenstrom's Macroglobulinemia. Current treatment options in oncology 20070401
Outline for writing an article for current treatment options in oncology: splenic lymphoma with villous lymphocytes. Current treatment options in oncology 20070401
Splenic marginal zone lymphoma with and without villous lymphocytes. Current treatment options in oncology 20070401
Hairy Cell Leukemia. Current treatment options in oncology 20070401
Molecular and functional analyses of a novel class I secretory nuclease from the human pathogen, Leishmania donovani. The Journal of biological chemistry 20070330
In vitro ligation of oligodeoxynucleotides containing C8-oxidized purine lesions using bacteriophage T4 DNA ligase. Biochemistry 20070327
How do size-expanded DNA nucleobases enhance duplex stability? Computational analysis of the hydrogen-bonding and stacking ability of xDNA bases. The journal of physical chemistry. B 20070322
Fluorescent HIV-1 Dimerization Initiation Site: design, properties, and use for ligand discovery. Journal of the American Chemical Society 20070321
8-Azaguanine reporter of purine ionization states in structured RNAs. Journal of the American Chemical Society 20070321
[Advances in the management of gout]. Revue medicale suisse 20070321
The c-Myc target gene Rcl (C6orf108) encodes a novel enzyme, deoxynucleoside 5'-monophosphate N-glycosidase. The Journal of biological chemistry 20070316
Mutagenesis of non-conserved active site residues improves the activity and narrows the specificity of human thymidine kinase 2. Biochemical and biophysical research communications 20070316
High-resolution dynamics of the transcriptional response to nutrition in Drosophila: a key role for dFOXO. Physiological genomics 20070314
Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis. Journal of molecular biology 20070309
Lymphoblasts of women with BRCA1 mutations are deficient in cellular repair of 8,5'-Cyclopurine-2'-deoxynucleosides and 8-hydroxy-2'-deoxyguanosine. Biochemistry 20070306
Structural and kinetic evidence for an extended hydrogen-bonding network in catalysis of methyl group transfer. Role of an active site asparagine residue in activation of methyl transfer by methyltransferases. The Journal of biological chemistry 20070302
Progressive multifocal leukoencephalopathy in purine nucleoside phosphorylase deficiency. Brain & development 20070301
Purification of human malaria parasite hypoxanthine guanine xanthine phosphoribosyltransferase (HGXPRT) using immobilized Reactive Red 120. Protein expression and purification 20070301
Kinetic characterization of inosine monophosphate dehydrogenase of Leishmania donovani. Molecular and biochemical parasitology 20070301
Molecular interactions underlying the unusually high adenosine affinity of a novel Trypanosoma brucei nucleoside transporter. Molecular pharmacology 20070301
Synthesis, characterization and assessment of the cytotoxic properties of cis and trans-[Pd(L)(2)Cl(2)] complexes involving 6-benzylamino-9-isopropylpurine derivatives. Journal of inorganic biochemistry 20070301
The G51S purine nucleoside phosphorylase polymorphism is associated with cognitive decline in Alzheimer's disease patients. Human psychopharmacology 20070301
A Francisella tularensis subspecies novicida purF mutant, but not a purA mutant, induces protective immunity to tularemia in mice. Vaccine 20070301
Role of neuronal nitric oxide in the dopamine deficit of HPRT-deficient mice. Metabolic brain disease 20070301
NF-kappaB activation in development and progression of cancer. Cancer science 20070301
Effects of low rumen-degradable protein or abomasal fructan infusion on diet digestibility and urinary nitrogen excretion in lactating dairy cows. Journal of dairy science 20070301
FMRP mediates mGluR5-dependent translation of amyloid precursor protein. PLoS biology 20070301
Changes in purine specificity in tandem GAF chimeras from cyanobacterial cyaB1 adenylate cyclase and rat phosphodiesterase 2. The FEBS journal 20070301
Plasma levels of uridine correlate with blood pressure and indicators of myogenic purine degradation and insulin resistance in hypertensive patients. Circulation journal : official journal of the Japanese Circulation Society 20070301
Structure of 5-formyltetrahydrofolate cyclo-ligase from Bacillus anthracis (BA4489). Acta crystallographica. Section F, Structural biology and crystallization communications 20070301
CD4+ cell count decline despite HIV suppression: a probable didanosine-valganciclovir interaction. The Annals of pharmacotherapy 20070301
Adenosine enhances cytosolic phosphorylation potential and ventricular contractility in stunned guinea pig heart: receptor-mediated and metabolic protection. Journal of applied physiology (Bethesda, Md. : 1985) 20070301
Purine nucleoside phosphorylase: a potential target for the development of drugs to treat T-cell- and apicomplexan parasite-mediated diseases. Current drug targets 20070301
The tightly regulated promoter of the xanA gene of Aspergillus nidulans is included in a helitron. Molecular microbiology 20070301
Exquisite sensitivity of TP53 mutant and basal breast cancers to a dose-dense epirubicin-cyclophosphamide regimen. PLoS medicine 20070301
6-mercaptopurine (6-MP) entrapped stealth liposomes for improvement of leukemic treatment without hepatotoxicity and nephrotoxicity. Cancer investigation 20070301
Fluocinolone acetonide intravitreal sustained release device--a new addition to the armamentarium of uveitic management. International journal of nanomedicine 20070301
Structural and transcriptional analyses of a purine nucleotide-binding protein from Pyrococcus furiosus: a component of a novel, membrane-bound multiprotein complex unique to this hyperthermophilic archaeon. Journal of structural and functional genomics 20070301
Therapy of autoimmune bullous diseases. Therapeutics and clinical risk management 20070301
Outcomes and quality of life issues in the pharmacological management of benign prostatic hyperplasia (BPH). Therapeutics and clinical risk management 20070301
Chemotactic activity of extracellular nucleotideson human immune cells. Purinergic signalling 20070301
Nucleotide receptor signalling and the generation of reactive oxygen species. Purinergic signalling 20070301
Extracellular NAD and ATP: Partners in immune cell modulation. Purinergic signalling 20070301
The role of released ATP in killing Candida albicans and other extracellular microbial pathogens by cationic peptides. Purinergic signalling 20070301
Adenosine and lymphocyte regulation. Purinergic signalling 20070301
Purinergic modulation of microglial cell activation. Purinergic signalling 20070301
P2 receptors in atherosclerosis and postangioplasty restenosis. Purinergic signalling 20070301
CD39 and control of cellular immune responses. Purinergic signalling 20070301
Palladium-catalyzed cross-coupling reactions in c6 modifications of purine nucleosides. Current protocols in nucleic acid chemistry 20070301
Effects of a dietary organic acid mixture and of dietary fibre levels on ileal and faecal nutrient apparent digestibility, bacterial nitrogen flow, microbial metabolite concentrations and rate of passage in the digestive tract of pigs. Animal : an international journal of animal bioscience 20070301
[Cloning and fusion expression of adenosine deaminase of Schistosoma japonicum]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases 20070227
HPLC separation of some purine and pyrimidine derivatives on Chromolith Performance Si monolithic column. Journal of biochemical and biophysical methods 20070223
2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists. Journal of medicinal chemistry 20070222
Fluorescent pyrimidine ribonucleotide: synthesis, enzymatic incorporation, and utilization. Journal of the American Chemical Society 20070221
Biomarkers for phenol carcinogen exposure act as pH-sensing fluorescent probes. Journal of the American Chemical Society 20070221
Simultaneous detection of purine and pyrimidine at highly boron-doped diamond electrodes by using liquid chromatography. Talanta 20070215
Specific mutations in transmembrane helix 8 of human concentrative Na+/nucleoside cotransporter hCNT1 affect permeant selectivity and cation coupling. Biochemistry 20070213
Gemcitabine chemoresistance and molecular markers associated with gemcitabine transport and metabolism in human pancreatic cancer cells. British journal of cancer 20070212
tRNA's wobble decoding of the genome: 40 years of modification. Journal of molecular biology 20070209
Crystal structure of human inosine triphosphatase. Substrate binding and implication of the inosine triphosphatase deficiency mutation P32T. The Journal of biological chemistry 20070202
Implication of site quality on mitochondrial electron transport activity and its interaction with temperature in feral Mya arenaria clams from the Saguenay Fjord. Environmental research 20070201
Towards the mechanism of trimeric purine nucleoside phosphorylases: stopped-flow studies of binding of multisubstrate analogue inhibitor - 2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine. Biophysical chemistry 20070201
Analysis of aminoimidazole ribosides by capillary electrophoresis--diagnosing defects in second part of purine biosynthetic pathway. Clinica chimica acta; international journal of clinical chemistry 20070201
Shaping of monocyte and macrophage function by adenosine receptors. Pharmacology & therapeutics 20070201
Roscovitine regulates invasive breast cancer cell (MDA-MB231) proliferation and survival through cell cycle regulatory protein cdk5. Experimental and molecular pathology 20070201
Xanthinuria type I: a rare cause of urolithiasis. Pediatric nephrology (Berlin, Germany) 20070201
Purine and pyrimidine nucleosides preserve human astrocytoma cell adenylate energy charge under ischemic conditions. Neurochemistry international 20070201
Pharmacological inhibition of the MAPK/ERK pathway increases sensitivity to 2-chloro-2'-deoxyadenosine (CdA) in the B-cell leukemia cell line EHEB. Biochemical pharmacology 20070201
Purinergic signaling regulates neural progenitor cell expansion and neurogenesis. Developmental biology 20070201
Capillary electrophoretic method for nucleotide analysis in cells: application on inherited metabolic disorders. Electrophoresis 20070201
Looking for organization patterns of highly expressed genes: purine-pyrimidine composition of precursor mRNAs. Journal of molecular evolution 20070201
Oxypurine and purine nucleoside concentrations in renal vein of allograft are potential markers of energy status of renal tissue. Archives of medical research 20070201
Effects of essential oils on digestion, ruminal fermentation, rumen microbial populations, milk production, and milk composition in dairy cows fed alfalfa silage or corn silage. Journal of dairy science 20070201
Substrate analogs induce an intermediate conformational change in Toxoplasma gondii adenosine kinase. Acta crystallographica. Section D, Biological crystallography 20070201
'Multicolor' electrochemical labeling of DNA hybridization probes with osmium tetroxide complexes. Analytical chemistry 20070201
Alemtuzumab in chronic lymphocytic leukemia. Future oncology (London, England) 20070201
Crystal Structures of the p21-activated kinases PAK4, PAK5, and PAK6 reveal catalytic domain plasticity of active group II PAKs. Structure (London, England : 1993) 20070201
The role of mitochondrial DNA mutations in mammalian aging. PLoS genetics 20070201
Nature and position of functional group on thiopurine substrates influence activity of xanthine oxidase--enzymatic reaction pathways of 6-mercaptopurine and 2-mercaptopurine are different. Biochemistry. Biokhimiia 20070201
Systemic monotherapy vs combination therapy for CTCL: rationale and future strategies. Oncology (Williston Park, N.Y.) 20070201
Inhibition and structure of Trichomonas vaginalis purine nucleoside phosphorylase with picomolar transition state analogues. Biochemistry 20070123
Hydrodynamic studies on the quaternary structure of recombinant mouse Purbeta. The Journal of biological chemistry 20070119
Pre-steady-state kinetic study of substrate specificity of Escherichia coli formamidopyrimidine--DNA glycosylase. Biochemistry 20070116
Human DNA polymerase alpha uses a combination of positive and negative selectivity to polymerize purine dNTPs with high fidelity. Biochemistry 20070116
Direct labeling microRNA with an electrocatalytic moiety and its application in ultrasensitive microRNA assays. Biosensors & bioelectronics 20070115
Enantioselective synthesis and antiviral activity of purine and pyrimidine cyclopentenyl C-nucleosides. Bioorganic & medicinal chemistry 20070115
A phase I trial of the selective oral cyclin-dependent kinase inhibitor seliciclib (CYC202; R-Roscovitine), administered twice daily for 7 days every 21 days. British journal of cancer 20070115
Guanosine inhibits CD40 receptor expression and function induced by cytokines and beta amyloid in mouse microglia cells. Journal of immunology (Baltimore, Md. : 1950) 20070115
Dissociation of nitric oxide from soluble guanylate cyclase and heme-nitric oxide/oxygen binding domain constructs. The Journal of biological chemistry 20070112
4-hydroxyequilenin-adenine lesions in DNA duplexes: stereochemistry, damage site, and structure. Biochemistry 20070109
Different DNA repair strategies to combat the threat from 8-oxoguanine. Mutation research 20070103
Enhanced toxicity of purine nucleoside analogs in cells expressing Drosophila melanogaster nucleoside kinase mutants. Gene therapy 20070101
Gene duplication and inactivation in the HPRT gene family. Genomics 20070101
Prokaryotes that grow optimally in acid have purine-poor codons in long open reading frames. Extremophiles : life under extreme conditions 20070101
Conformations of adducts formed between the genotoxic benzo[a]pyrene-7,8-dione and nucleosides studied by density functional theory. Biophysical chemistry 20070101
Uric acid inhibits renal proximal tubule cell proliferation via at least two signaling pathways involving PKC, MAPK, cPLA2, and NF-kappaB. American journal of physiology. Renal physiology 20070101
A purine analog kinase inhibitor, calcium/calmodulin-dependent protein kinase II inhibitor 59, reveals a role for calcium/calmodulin-dependent protein kinase II in insulin-stimulated glucose transport. Endocrinology 20070101
Mechanisms of DNA damage and insight into mutations by chromium(VI) in the presence of glutathione. Journal of inorganic biochemistry 20070101
Molecular analysis of HPRT deficiencies: an update of the spectrum of Asian mutations with novel mutations. Molecular genetics and metabolism 20070101
Indications for allogeneic stem cell transplantation in chronic lymphocytic leukemia: the EBMT transplant consensus. Leukemia 20070101
Clinical, biochemical and molecular diagnosis of a compound homozygote for the 254 bp deletion-8 bp insertion of the APRT gene suffering from severe renal failure. Clinical biochemistry 20070101
Synthesis and biological activity of 5',9-anhydro-3-purine-isonucleosides as potential anti-hepatitis C virus agents. Nucleosides, nucleotides & nucleic acids 20070101
Temperature-dependent effects of cadmium and purine nucleotides on mitochondrial aconitase from a marine ectotherm, Crassostrea virginica: a role of temperature in oxidative stress and allosteric enzyme regulation. The Journal of experimental biology 20070101
Involvement of rapid nucleotide synthesis in recovery from phosphate starvation of Catharanthus roseus cells. Journal of experimental botany 20070101
Revised procedures for yeast metabolites extraction: application to a glucose pulse to carbon-limited yeast cultures, which reveals a transient activation of the purine salvage pathway. Yeast (Chichester, England) 20070101
Monitoring diet effects via biofluids and their implications for metabolomics studies. Analytical chemistry 20070101
Exogenous purines induce differential responses in the proximal and distal regions of the possum sphincter of Oddi. Autonomic & autacoid pharmacology 20070101
An annotated catalogue of salivary gland transcripts in the adult female mosquito, Aedes aegypti. BMC genomics 20070101
Identification of putative cis-regulatory elements in Cryptosporidium parvum by de novo pattern finding. BMC genomics 20070101
Energetics of the protein-DNA-water interaction. BMC structural biology 20070101
Phosphoramidate pronucleotides: a comparison of the phosphoramidase substrate specificity of human and Escherichia coli histidine triad nucleotide binding proteins. Molecular pharmaceutics 20070101
Protein and DNA sequence determinants of thermophilic adaptation. PLoS computational biology 20070101
Distinct pigmentary and melanocortin 1 receptor-dependent components of cutaneous defense against ultraviolet radiation. PLoS genetics 20070101
Conformation-specific recognition of carcinogen-DNA adduct in escherichia coli nucleotide excision repair. Chemical research in toxicology 20070101
The dystrotelin, dystrophin and dystrobrevin superfamily: new paralogues and old isoforms. BMC genomics 20070101
GraphDNA: a Java program for graphical display of DNA composition analyses. BMC bioinformatics 20070101
Role of adenosine receptors in the treatment of asthma and chronic obstructive pulmonary disease: recent developments. Drugs in R&D 20070101
On the action of methotrexate and 6-mercaptopurine on M. avium subspecies paratuberculosis. PloS one 20070101
Anti-proliferative activity of the quassinoid NBT-272 in childhood medulloblastoma cells. BMC cancer 20070101
Independent evolution of the specialized pharyngeal jaw apparatus in cichlid and labrid fishes. BMC evolutionary biology 20070101
Targeting purine and pyrimidine metabolism in human apicomplexan parasites. Current drug targets 20070101
Differential gene expression patterns in cyclooxygenase-1 and cyclooxygenase-2 deficient mouse brain. Genome biology 20070101
Classification of microarray data using gene networks. BMC bioinformatics 20070101
The +4G site in Kozak consensus is not related to the efficiency of translation initiation. PloS one 20070101
Serum uric acid to creatinine ratio in patients with chronic obstructive pulmonary disease. Lung 20070101
Characterization of relationships between transcriptional units and operon structures in Bacillus subtilis and Escherichia coli. BMC genomics 20070101
[Iminosugars: current and future therapeutic applications]. Annales pharmaceutiques francaises 20070101
Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: a meta-analysis. International journal of medical sciences 20070101
Genetic distance and heterogenecity between quasispecies is a critical predictor to IFN response in Egyptian patients with HCV genotype-4. Virology journal 20070101
Patterns and rates of intron divergence between humans and chimpanzees. Genome biology 20070101
Mass spectrometric study of dirhenium biscarboxylate:purine dinucleotide complexes. Rapid communications in mass spectrometry : RCM 20070101
Results of a phase II study of 506U78 in cutaneous T-cell lymphoma and peripheral T-cell lymphoma: CALGB 59901. Leukemia & lymphoma 20070101
Cyclin-dependent kinase inhibitor seliciclib shows in vitro activity in diffuse large B-cell lymphomas. Leukemia & lymphoma 20070101
A mathematical model for the adenylosuccinate synthetase reaction involved in purine biosynthesis. Theoretical biology & medical modelling 20070101
Strategy of transcription regulation in the budding yeast. PloS one 20070101
Chemotherapeutic strategies against Trypanosoma brucei: drug targets vs. drug targeting. Current pharmaceutical design 20070101
Nucleoside transport as a potential target for chemotherapy in malaria. Current pharmaceutical design 20070101
Adenosine metabolism in Toxoplasma gondii: potential targets for chemotherapy. Current pharmaceutical design 20070101
Purine metabolism in Mycobacterium tuberculosis as a target for drug development. Current pharmaceutical design 20070101
Traceless solid-phase synthesis and biological evaluation of purine analogs as inhibitors of multidrug resistance protein 4. Journal of combinatorial chemistry 20070101
Quantifying the metabolic capabilities of engineered Zymomonas mobilis using linear programming analysis. Microbial cell factories 20070101
Aromatic heterocycle-based DPP-IV inhibitors: xanthines and related structural types. Current topics in medicinal chemistry 20070101
Replicative homeostasis III: implications for antiviral therapy and mechanisms of response and non-response. Virology journal 20070101
Fast computation of distance estimators. BMC bioinformatics 20070101
Transcriptional profiling of Actinobacillus pleuropneumoniae under iron-restricted conditions. BMC genomics 20070101
Genetic studies of a cluster of acute lymphoblastic leukemia cases in Churchill County, Nevada. Environmental health perspectives 20070101
The role of the purinergic P2X7 receptor in inflammation. Journal of inflammation (London, England) 20070101
Reactome: a knowledge base of biologic pathways and processes. Genome biology 20070101
Quantum mechanical energy-based screening of combinatorially generated library of tautomers. TauTGen: a tautomer generator program. Journal of chemical information and modeling 20070101
Colectomy rate in steroid-refractory colitis initially responsive to cyclosporin: a long-term retrospective cohort study. BMC gastroenterology 20070101
Rosai-Dorfman disease: a previously unreported association with sickle cell disease. BMC clinical pathology 20070101
Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray. BMC genomics 20070101
METANNOGEN: compiling features of biochemical reactions needed for the reconstruction of metabolic networks. BMC systems biology 20070101
Correlation analysis reveals the emergence of coherence in the gene expression dynamics following system perturbation. BMC bioinformatics 20070101
Pyoderma gangrenosum--a review. Orphanet journal of rare diseases 20070101
A novel small molecule that selectively inhibits glioblastoma cells expressing EGFRvIII. Molecular cancer 20070101
Associations of common polymorphisms in the thymidylate synthase, reduced folate carrier and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase/inosine monophosphate cyclohydrolase genes with folate and homocysteine levels and venous thrombosis risk. Clinical chemistry and laboratory medicine 20070101
Growth control of the eukaryote cell: a systems biology study in yeast. Journal of biology 20070101
A novel approach for determining cancer genomic breakpoints in the presence of normal DNA. PloS one 20070101
Influence of heating on the activity of xanthine oxidase in tumor cells subjected to the phototoxic action of hematoporphyrin derivative. Neoplasma 20070101
Genome-wide transcriptional plasticity underlies cellular adaptation to novel challenge. Molecular systems biology 20070101
Cation coupling properties of human concentrative nucleoside transporters hCNT1, hCNT2 and hCNT3. Molecular membrane biology 20070101
Hypoxanthine-guanine phosphoribosyltransferase deficiency: biochemical and molecular findings in six Argentine patients. Nucleosides, nucleotides & nucleic acids 20070101
Selective photo-cross-linking of 2'-O-psoralen-conjugated oligonucleotide with RNAs having point mutations. Nucleosides, nucleotides & nucleic acids 20070101
Oxypurine and nucleoside concentrations in renal veins during reperfusion are predictors of early graft function. Scandinavian journal of urology and nephrology 20070101
Global gene expression analysis and regulation of the principal genes expressed in bovine placenta in relation to the transcription factor AP-2 family. Reproductive biology and endocrinology : RB&E 20070101
Sequence-dependent administration of raloxifene and 5-fluorouracil/pemetrexed protects against pemetrexed cytotoxicity in human bone marrow. Anticancer research 20070101
Diversifying selection and host adaptation in two endosymbiont genomes. BMC evolutionary biology 20070101
Interplay between exonic splicing enhancers, mRNA processing, and mRNA surveillance in the dystrophic Mdx mouse. PloS one 20070101
Discovery and characterization of 91 novel transcripts expressed in cattle placenta. BMC genomics 20070101
Effects of AIT-082, a purine derivative, on tremor induced by arecoline or oxotremorine in mice. Pharmacology 20070101
Thermolabile methylenetetrahydrofolate reductase C677T polymorphism and homocysteine are risk factors for coronary artery disease in Moroccan population. Journal of biomedicine & biotechnology 20070101
Revealing signaling pathway deregulation by using gene expression signatures and regulatory motif analysis. Genome biology 20070101
Postjunctional synergism of norepinephrine with ATP and diadenosine tetraphosphate in Guinea pig vas deferens. Role of protein kinase C and Myosin light chain phosphatase. Pharmacology 20070101
The crystal structure of Escherichia coli TdcF, a member of the highly conserved YjgF/YER057c/UK114 family. BMC structural biology 20070101
Preferential inhibition of xanthine oxidase by 2-amino-6-hydroxy-8-mercaptopurine and 2-amino-6-purine thiol. BMC biochemistry 20070101
The Arabidopsis thaliana brassinosteroid receptor (AtBRI1) contains a domain that functions as a guanylyl cyclase in vitro. PloS one 20070101
Structural insights into the evolution of a non-biological protein: importance of surface residues in protein fold optimization. PloS one 20070101
Regulation of expression and kinetic modeling of substrate interactions of a uracil transporter in Aspergillus nidulans. Molecular membrane biology 20070101
Adenosine arrests apoptosis in lymphocytes but not in phagocytes from primary leucocyte cultures of the teleost fish, Sparus aurata L. Developmental and comparative immunology 20070101
Modular architecture of protein structures and allosteric communications: potential implications for signaling proteins and regulatory linkages. Genome biology 20070101
The integration of lipid-sensing and anti-inflammatory effects: how the PPARs play a role in metabolic balance. Nuclear receptor 20070101
Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice. Molecular neurodegeneration 20070101
NGF-mediated transcriptional targets of p53 in PC12 neuronal differentiation. BMC genomics 20070101
Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome biology 20070101
Comparative temporal and dose-dependent morphological and transcriptional uterine effects elicited by tamoxifen and ethynylestradiol in immature, ovariectomized mice. BMC genomics 20070101
[Treatment of hairy cell leukemia with cladribine]. Lijecnicki vjesnik 20070101
Identification of regulatory network topological units coordinating the genome-wide transcriptional response to glucose in Escherichia coli. BMC microbiology 20070101
Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger. BMC genomics 20070101
Transcriptome changes and cAMP oscillations in an archaeal cell cycle. BMC cell biology 20070101
Circadian distribution of serum cytokines in multiple sclerosis. La Clinica terapeutica 20070101
A content-centric organization of the genetic code. Genomics, proteomics & bioinformatics 20070101
Identification of genes differentially expressed during larval molting and metamorphosis of Helicoverpa armigera. BMC developmental biology 20070101
Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma. PloS one 20070101
Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes. BMC cancer 20070101
Observing metabolic functions at the genome scale. Genome biology 20070101
Correcting for sequence biases in present/absent calls. Genome biology 20070101
The entire organization of transcription units on the Bacillus subtilis genome. BMC genomics 20070101
In silico comparative genomic analysis of GABAA receptor transcriptional regulation. BMC genomics 20070101
Isolation and characterization of human cells resistant to retrovirus infection. Retrovirology 20070101
Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets. BMC genomics 20070101
Transcriptional recapitulation and subversion of embryonic colon development by mouse colon tumor models and human colon cancer. Genome biology 20070101
Cloning and expression of a zebrafish SCN1B ortholog and identification of a species-specific splice variant. BMC genomics 20070101
Uric acid reduction: a new paradigm in the management of cardiovascular risk? Current medicinal chemistry 20070101
Molecular and functional analysis of hypoxanthine-guanine phosphoribosyltransferase from Arabidopsis thaliana. The New phytologist 20070101
Fludarabine: a review of its use in non-Hodgkin's lymphoma. Drugs 20070101
Identification of modified residues in RNAs by reverse transcription-based methods. Methods in enzymology 20070101
Hairy cell leukemia. Medical oncology (Northwood, London, England) 20070101
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data. BMC bioinformatics 20070101
Effects of folate cycle disruption by the green tea polyphenol epigallocatechin-3-gallate. The international journal of biochemistry & cell biology 20070101
ISN1 nucleotidases and HAD superfamily protein fold: in silico sequence and structure analysis. In silico biology 20070101
[Effect of warmth-promotion needling on cerebral SOD, MDA and AChE in vascular dementia rats]. Zhen ci yan jiu = Acupuncture research 20070101
Hitting bacteria at the heart of the central dogma: sequence-specific inhibition. Microbial cell factories 20070101
Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate. BMC genomics 20070101
Complete deficiency of 5'-nucleotidase activity in Escherichia coli leads to loss of growth on purine nucleotides but not of their excretion. Journal of molecular microbiology and biotechnology 20070101
FDG-PET detection of primary bone marrow large B-cell lymphoma in a patient with hairy cell leukemia. Nuclear medicine review. Central & Eastern Europe 20070101
Engineering a selective small-molecule substrate binding site into a deoxyribozyme. Angewandte Chemie (International ed. in English) 20070101
Naturally occurring and stress induced tubular structures from mammalian cells, a survival mechanism. BMC cell biology 20070101
Induction of apoptosis by alkaloids, non-protein amino acids, and cardiac glycosides in human promyelotic HL-60 cells. Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
Genome bioinformatic analysis of nonsynonymous SNPs. BMC bioinformatics 20070101
Genome-wide polysomal analysis of a yeast strain with mutated ribosomal protein S9. BMC genomics 20070101
Quantitative analysis of mutation and selection pressures on base composition skews in bacterial chromosomes. BMC genomics 20070101
Efficient construction of an inverted minimal H1 promoter driven siRNA expression cassette: facilitation of promoter and siRNA sequence exchange. PloS one 20070101
Sterility and gene expression in hybrid males of Xenopus laevis and X. muelleri. PloS one 20070101
Thioredoxin reductase is a key factor in the oxidative stress response of Lactobacillus plantarum WCFS1. Microbial cell factories 20070101
Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery. Genome biology 20070101
Effect of active smoking on the human bronchial epithelium transcriptome. BMC genomics 20070101
AUG_hairpin: prediction of a downstream secondary structure influencing the recognition of a translation start site. BMC bioinformatics 20070101
Automatic generation of 3D motifs for classification of protein binding sites. BMC bioinformatics 20070101
Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax: new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes. BMC genomics 20070101
The mitochondrial genome of Phallusia mammillata and Phallusia fumigata (Tunicata, Ascidiacea): high genome plasticity at intra-genus level. BMC evolutionary biology 20070101
Cysteinyl-leukotriene receptors and cellular signals. TheScientificWorldJournal 20070101
Formamide as the main building block in the origin of nucleic acids. BMC evolutionary biology 20070101
The role of gene fusions in the evolution of metabolic pathways: the histidine biosynthesis case. BMC evolutionary biology 20070101
Living with an imperfect cell wall: compensation of femAB inactivation in Staphylococcus aureus. BMC genomics 20070101
Structural and functional analyses of five conserved positively charged residues in the L1 and N-terminal DNA binding motifs of archaeal RADA protein. PloS one 20070101
Metabolome based reaction graphs of M. tuberculosis and M. leprae: a comparative network analysis. PloS one 20070101
EDISA: extracting biclusters from multiple time-series of gene expression profiles. BMC bioinformatics 20070101
Effects of salicylic acid on post-ischaemic ventricular function and purine efflux in isolated mouse hearts. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20070101
Ion channel diversity, channel expression and function in the choroid plexuses. Cerebrospinal fluid research 20070101
Environmental variability and modularity of bacterial metabolic networks. BMC evolutionary biology 20070101
Gene discovery and transcript analyses in the corn smut pathogen Ustilago maydis: expressed sequence tag and genome sequence comparison. BMC genomics 20070101
The G protein-coupled receptor subset of the rat genome. BMC genomics 20070101
Crystal structure of Leishmania tarentolae hypoxanthine-guanine phosphoribosyltransferase. BMC structural biology 20070101
Deinococcus geothermalis: the pool of extreme radiation resistance genes shrinks. PloS one 20070101
Dynamic remodelling of synapses can occur in the absence of the parent cell body. BMC neuroscience 20070101
Behavioral genetics and taste. BMC neuroscience 20070101
RNAspa: a shortest path approach for comparative prediction of the secondary structure of ncRNA molecules. BMC bioinformatics 20070101
Abundance and functional diversity of riboswitches in microbial communities. BMC genomics 20070101
Conservation, variability and the modeling of active protein kinases. PloS one 20070101
Genetic subtraction profiling identifies genes essential for Arabidopsis reproduction and reveals interaction between the female gametophyte and the maternal sporophyte. Genome biology 20070101
Understanding the mechanisms of action of methotrexate: implications for the treatment of rheumatoid arthritis. Bulletin of the NYU hospital for joint diseases 20070101
An unusual case of gout in the wrist: the importance of monitoring medication dosage and interaction. A case report. Chiropractic & osteopathy 20070101
Separate base usages of genes located on the leading and lagging strands in Chlamydia muridarum revealed by the Z curve method. BMC genomics 20070101
[Combination of purine analogues and aminosalicylates in patients with inflammatory bowel disease: why and how?]. Gastroenterologie clinique et biologique 20070101
Separating the effects of mutation and selection in producing DNA skew in bacterial chromosomes. BMC genomics 20070101
A new function for the Bacillus PbuE purine base efflux pump: efflux of purine nucleosides. Research in microbiology 20070101
ADAM15 gene structure and differential alternative exon use in human tissues. BMC molecular biology 20070101
Sequences conserved by selection across mouse and human malaria species. BMC genomics 20070101
Instability of retroviral vectors with HIV-1-specific RT aptamers due to cryptic splice sites in the U6 promoter. AIDS research and therapy 20070101
Theacrine, a special purine alkaloid with sedative and hypnotic properties from Cammelia assamica var. kucha in mice. Journal of Asian natural products research 20070101
[Effects of mycophenolate mofetil in ischemic acute renal failure in rats]. Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20070101
Short sequence motifs, overrepresented in mammalian conserved non-coding sequences. BMC genomics 20070101
[Preliminary results of the effects of electromagnetic fields ELF and TAMMEF on human lymphocytes: evaluation of some biological parameters]. La Clinica terapeutica 20070101
Cloning of the canine RNA polymerase I promoter and establishment of reverse genetics for influenza A and B in MDCK cells. Virology journal 20070101
Control of gag-pol gene expression in the Candida albicans retrotransposon Tca2. BMC molecular biology 20070101
A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient. BMC bioinformatics 20070101
The implications of an incidental chronic lymphocytic leukaemia in a resection specimen for colorectal adenocarcinoma. World journal of surgical oncology 20070101
Recognition of essential purines by the U1A protein. BMC biochemistry 20070101
Myasthenia gravis. Orphanet journal of rare diseases 20070101
Fragment-based identification of determinants of conformational and spectroscopic change at the ricin active site. BMC structural biology 20070101
Blood parameters in growing pigs fed increasing levels of bacterial protein meal. Acta veterinaria Scandinavica 20070101
Evolution of temperate pathogens: the bacteriophage/bacteria paradigm. Virology journal 20070101
The distributions, mechanisms, and structures of metabolite-binding riboswitches. Genome biology 20070101
Rapid changes in gene expression dynamics in response to superoxide reveal SoxRS-dependent and independent transcriptional networks. PloS one 20070101
Management of infectious complications in patients with chronic lymphocytic leukemia. Hematology. American Society of Hematology. Education Program 20070101
Property editing of peptide nucleic acids (PNA): gem-dimethyl, cyanuryl and 8-aminoadenine PNAs. Nucleic acids symposium series (2004) 20070101
Functional reactivity of oxanine: its biological meanings and biotechnological applications. Nucleic acids symposium series (2004) 20070101
Location of the triplex DNA-binding domain of Saccharomyces cerevisiae Stm1 protein. Nucleic acids symposium series (2004) 20070101
Studies on DNA dynamics using 2-N-tert-butylaminoxylpurines. Nucleic acids symposium series (2004) 20070101
Repair mechanism of DNA-protein cross-link damage in Escherichia coli. Nucleic acids symposium series (2004) 20070101
Syntheses and properties of low-polarity shape mimics of 8-oxopurines. Nucleic acids symposium series (2004) 20070101
Fluorescence emission detection of single-nucleotide polymorphisms by a naphthyridine-benzofurazan conjugate. Nucleic acids symposium series (2004) 20070101
Development of stable DNA microarray platforms suitable for quantitative analysis. Nucleic acids symposium series (2004) 20070101
Enzymatic incorporation of 2-amino-6-vinylpurine derivative. Nucleic acids symposium series (2004) 20070101
In vitro selection of a 5'-purine nucleotide transferase ribozyme. Nucleic acids symposium series (2004) 20070101
Synthesis and evaluation of 9-deazaguanine derivatives as multi-substrate analogue inhibitors of PNP. Nucleic acids symposium series (2004) 20070101
Suppression of subgenomic hepatitis C virus replication by 5'-O-masked analogues of 6-chloropurine-2'-deoxyriboside. Nucleic acids symposium series (2004) 20070101
Comparison of enzymatic recognition of DNA-duplexes containing NO-induced lesions by DNA-relevant enzymes. Nucleic acids symposium series (2004) 20070101
[2,8-dihydroxyadenine nephrolithiasis: from diagnosis to therapy]. Annales de biologie clinique 20070101
Age-related subproteomic analysis of mouse liver and kidney peroxisomes. Proteome science 20070101
Proteomic shifts in embryonic stem cells with gene dose modifications suggest the presence of balancer proteins in protein regulatory networks. PloS one 20070101
Gene organization in rice revealed by full-length cDNA mapping and gene expression analysis through microarray. PloS one 20070101
Purinergic (P2) receptor control of lower genitourinary tract function and new avenues for drug action: an overview. Current pharmaceutical design 20070101
Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling. BMC biochemistry 20070101
Systems biology approach for mapping the response of human urothelial cells to infection by Enterococcus faecalis. BMC bioinformatics 20070101
The oncoprotein H-RasV12 increases mitochondrial metabolism. Molecular cancer 20070101
An enzymatic transglycosylation of purine bases. Nucleosides, nucleotides & nucleic acids 20070101
Kinetics of binding of multisubstrate analogue inhibitor (2-amino-9-[2-(phosphonomethoxy)ethyl]-6-sulfanylpurine) with trimeric purine nucleoside phosphorylase. Nucleosides, nucleotides & nucleic acids 20070101
Triplex formation using oligonucleotide clamps carrying 8-aminopurines. Nucleosides, nucleotides & nucleic acids 20070101
Inhibitory properties of nucleotides with difluoromethylenephosphonic acid as a phosphate mimic versus calf spleen purine nucleoside phosphorylase and effect of these analogues on the viability of human blood lymphocytes. Nucleosides, nucleotides & nucleic acids 20070101
Synthesis study of 2'-O-(2-methoxyethyl)-purine derivatives. Nucleosides, nucleotides & nucleic acids 20070101
Affinity of dinucleotide cap analogues for human decapping scavenger (hDcpS). Nucleosides, nucleotides & nucleic acids 20070101
Looking for new pyrimidine acyclic nucleotide analogues designed for phosphorylation by human UMP-CMP kinase. Nucleosides, nucleotides & nucleic acids 20070101
Biophysical stability and enzymatic recognition of oxanine in DNA. Nucleosides, nucleotides & nucleic acids 20070101
2'-deoxyadenosine bearing hydrophobic carborane pharmacophore. Nucleosides, nucleotides & nucleic acids 20070101
Some novel aminopropyl nucleoside phosphonates. Nucleosides, nucleotides & nucleic acids 20070101
Fluorescence studies of calf spleen purine nucleoside phosphorylase (PNP) complexes with guanine and 9-deazaguanine. Nucleosides, nucleotides & nucleic acids 20070101
Interactions of calf spleen purine nucleoside phosphorylase with formycin B and its aglycone - spectroscopic and kinetic studies. Nucleosides, nucleotides & nucleic acids 20070101
Cloning, expression, purification, and some properties of calf purine nucleoside phosphorylase. Nucleosides, nucleotides & nucleic acids 20070101
Hypoxanthine-guanine phosophoribosyltransferase (HPRT) deficiency: Lesch-Nyhan syndrome. Orphanet journal of rare diseases 20070101
Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes. Genome biology 20070101
Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells. BMC genomics 20070101
Measurement of cell proliferation by heavy water labeling. Nature protocols 20070101
Measurement of very low rates of cell proliferation by heavy water labeling of DNA and gas chromatography/pyrolysis/isotope ratio-mass spectrometric analysis. Nature protocols 20070101
Restriction site-dependent PCR: an efficient technique for fast cloning of new genes of microorganisms. DNA research : an international journal for rapid publication of reports on genes and genomes 20070101
Profiling sex-biased gene expression during parthenogenetic reproduction in Daphnia pulex. BMC genomics 20070101
Azathioprine in dermatology. Acta dermatovenerologica Croatica : ADC 20070101
Enzymatic and extraenzymatic role of adenosine deaminase 1 in T-cell-dendritic cell contacts and in alterations of the immune function. Critical reviews in immunology 20070101
Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex. Current medicinal chemistry 20070101
Severe and steroid-resistant Crohn's disease. Digestion 20070101
A scenario on the stepwise evolution of the genetic code. Genomics, proteomics & bioinformatics 20070101
Characterization of copper(II) interactions with sinefungin, a nucleoside antibiotic: combined potentiometric, spectroscopic and DFT studies. Bioinorganic chemistry and applications 20070101
Guanine and inosine nucleotides, nucleosides and oxypurines in snail muscles as potential biomarkers of fluoride toxicity. Folia biologica 20070101
Tumour Lysis Syndrome Occurring in a Patient with Metastatic Gastrointestinal Stromal Tumour Treated with Glivec (Imatinib Mesylate, Gleevec, STI571). Sarcoma 20070101
[Influence of asbestos dust combination with radiation on activity of enzymes involved into purine nucleotides metabolism in various tissues and organs]. Meditsina truda i promyshlennaia ekologiia 20070101
Treatment of transformed mycosis fungoides with intermittent low-dose gemcitabine. Oncology 20070101
Complexes of Pd(II) and Pt(II) with 9-aminoacridine: reactions with DNA and study of their antiproliferative activity. Bioinorganic chemistry and applications 20070101
Biochemical studies on the cardioprotective effect of glutamine on tissue antioxidant defense system in isoprenaline-induced myocardial infarction in rats. Journal of clinical biochemistry and nutrition 20070101
Abstracts of papers presented at the 2007 pittsburgh conference. Journal of automated methods & management in chemistry 20070101
The GC skew index: a measure of genomic compositional asymmetry and the degree of replicational selection. Evolutionary bioinformatics online 20070101
Clastogenic factors as potential biomarkers of increased superoxide production. Biomarker insights 20070101
Evaluation of children with urolithiasis. Indian journal of urology : IJU : journal of the Urological Society of India 20070101
Folate during reproduction: the Canadian experience with folic acid fortification. Nutrition research and practice 20070101
Rituximab maintenance in relapsed or refractory follicular non-Hodgkin's lymphoma: the evidence of its therapeutic value. Core evidence 20070101
Infliximab: the evidence for its place in therapy in ulcerative colitis. Core evidence 20070101
Modulation of visceral nociception, inflammation and gastric mucosal injury by cinnarizine. Drug target insights 20070101
Trypanothione reductase: a viable chemotherapeutic target for antitrypanosomal and antileishmanial drug design. Drug target insights 20070101
Cysteine-scanning analysis of the nucleobase-ascorbate transporter signature motif in YgfO permease of Escherichia coli: Gln-324 and Asn-325 are essential, and Ile-329-Val-339 form an alpha-helix. The Journal of biological chemistry 20061229
2-Aminopurine inhibits leptin receptor signal transduction. European journal of pharmacology 20061228
Interaction of low-energy electrons with the purine bases, nucleosides, and nucleotides of DNA. The Journal of chemical physics 20061228
Complexed structures of formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima describe a novel ATP binding protein superfamily. Biochemistry 20061219
Enzymatic assay of allantoin in serum using allantoinase and allantoate amidohydrolase. Analytical biochemistry 20061215
Strain differences in the responsiveness between Sprague-Dawley and Fischer rats to nephropathy induced by FYX-051, a xanthine oxidoreductase inhibitor. Toxicology and applied pharmacology 20061215
Electronic structure of DNA nucleobases and their dinucleotides explored by soft X-ray spectroscopy. The journal of physical chemistry. A 20061214
Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases. Journal of medicinal chemistry 20061214
Surface-enhanced Raman spectroscopy (SERS) for sub-micromolar detection of DNA/RNA mononucleotides. Journal of the American Chemical Society 20061213
Reversine-treated fibroblasts acquire myogenic competence in vitro and in regenerating skeletal muscle. Cell death and differentiation 20061201
Modification of p53 protein profile by gamma irradiation followed by methyl donor starvation. Molecular and cellular biochemistry 20061201
Characterization of the rat Na+/nucleoside cotransporter 2 and transport of nucleoside-derived drugs using electrophysiological methods. American journal of physiology. Cell physiology 20061201
Profiles of purine biosynthesis, salvage and degradation in disks of potato (Solanum tuberosum L.) tubers. Planta 20061201
Synthesis, X-ray crystal structural study, antiviral and cytostatic evaluations of the novel unsaturated acyclic and epoxide nucleoside analogues. Bioorganic & medicinal chemistry 20061201
Bioactivity of glycogen phosphorylase inhibitors that bind to the purine nucleoside site. Bioorganic & medicinal chemistry 20061201
Metabolic design of macroscopic bioreaction models: application to Chinese hamster ovary cells. Bioprocess and biosystems engineering 20061201
Metabolic functions of glycosomes in trypanosomatids. Biochimica et biophysica acta 20061201
A purine at +2 rather than +1 adjacent to the human U6 promoter is required to prepare effective short hairpin RNAs. Biochemical and biophysical research communications 20061201
Recognition of nucleotide analogs containing the 7,8-dihydro-8-oxo structure by the human MTH1 protein. Journal of biochemistry 20061201
On the hypothesis that the failing heart is energy starved: lessons learned from the metabolism of ATP and creatine. Current hypertension reports 20061201
Fluorescent analysis of translesion DNA synthesis by using a novel, non-natural nucleotide analogue. Chembiochem : a European journal of chemical biology 20061201
Novel purine nucleoside analogues for T-cell-lineage acute lymphoblastic leukaemia and lymphoma. Expert opinion on investigational drugs 20061201
The substrate specificity of tRNA (m1G37) methyltransferase (TrmD) from Aquifex aeolicus. Genes to cells : devoted to molecular & cellular mechanisms 20061201
Crystallization and preliminary X-ray analysis of human MTH1 complexed with two oxidized nucleotides, 8-oxo-dGMP and 2-oxo-dATP. Acta crystallographica. Section F, Structural biology and crystallization communications 20061201
An efficient method for homologous gene reconstitution in Cryptococcus gattii using URA5 auxotrophic marker. Mycopathologia 20061201
Changes in membrane conductance play a pathogenic role in osmotic glial cell swelling in detached retinas. The American journal of pathology 20061201
Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells. Leukemia & lymphoma 20061201
Computational reconstruction of iron- and manganese-responsive transcriptional networks in alpha-proteobacteria. PLoS computational biology 20061201
NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site. PLoS pathogens 20061201
Dynamics of the cellular metabolome during human cytomegalovirus infection. PLoS pathogens 20061201
Role of immunochemotherapy in the treatment of chronic lymphocytic leukemia. Expert review of anticancer therapy 20061201
Configuration of a scintillation proximity assay for the activity assessment of recombinant human adenine phosphoribosyltransferase. Assay and drug development technologies 20061201
Pathogenesis, clinical findings and management of acute and chronic gout. Minerva medica 20061201
Sprint training reduces urinary purine loss following intense exercise in humans. Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 20061201
[Perspectives in clinical immunology]. Recenti progressi in medicina 20061201
In vivo engineering of proteins with nitrogen-containing tryptophan analogs. Applied microbiology and biotechnology 20061201
Efficacy of low dose clofarabine in refractory precursor T- acute lymphoblastic leukemia. The Yale journal of biology and medicine 20061201
Hydration of mononucleotides. Journal of the American Chemical Society 20061129
Nonpolar nucleobase analogs illuminate requirements for site-specific DNA cleavage by vaccinia topoisomerase. The Journal of biological chemistry 20061124
Simple synthesis of some pentafluoropropenyl derivatives of pyrimidine and purine based on addition-elimination reaction. The Journal of organic chemistry 20061110
Regiospecific N9 alkylation of 6-(heteroaryl)purines: shielding of N7 by a proximal heteroaryl C-H1. The Journal of organic chemistry 20061110
Modified pyrimidines specifically bind the purine riboswitch. Journal of the American Chemical Society 20061108
C4' sugar oxidation of deoxyribonucleotide triphosphates by chromium(V) complexes. Mutation research 20061107
pH-Independent triplex formation: hairpin DNA containing isoguanine or 9-deaza-9-propynylguanine in place of protonated cytosine. Organic & biomolecular chemistry 20061107
Comparative studies on Ureide Permeases in Arabidopsis thaliana and analysis of two alternative splice variants of AtUPS5. Planta 20061101
Adenosine upregulates CXCR4 and enhances the proliferative and migratory responses of human carcinoma cells to CXCL12/SDF-1alpha. International journal of cancer 20061101
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects. Blood 20061101
A three-dimensional quantitative structure-activity relationship study of the inhibition of the ATPase activity and the strand passing catalytic activity of topoisomerase IIalpha by substituted purine analogs. Molecular pharmacology 20061101
Nucleotides and inorganic phosphates as potential antioxidants. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20061101
Interactions of 1,12-diamino-4,9-dioxadodecane (OSpm) and Cu(II) ions with pyrimidine and purine nucleotides: adenosine-5'-monophosphate (AMP) and cytidine-5'-monophosphate (CMP). Journal of inorganic biochemistry 20061101
Cladribine therapy in refractory celiac disease with aberrant T cells. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061101
Induction of A.T to G.C mutations by erroneous repair of depurinated DNA following estrogen treatment of the mammary gland of ACI rats. The Journal of steroid biochemistry and molecular biology 20061101
Clofarabine and nelarabine: two new purine nucleoside analogs. Current opinion in oncology 20061101
Subcellular compartmentalization of glutathione: correlations with parameters of oxidative stress related to genotoxicity. Mutagenesis 20061101
Adenosine and cytokine levels following treatment of rheumatoid arthritis with dipyridamole. Rheumatology international 20061101
Origin of informational polymers: The concurrent roles of formamide and phosphates. Chembiochem : a European journal of chemical biology 20061101
Regulation of purine nucleotide biosynthesis: in yeast and beyond. Biochemical Society transactions 20061101
Implementing tandem mass spectrometry as a routine tool for characterizing the complete purine and pyrimidine metabolic profile in urine samples. Journal of mass spectrometry : JMS 20061101
Atlantoaxial subluxation with recurrent consciousness disturbance in a boy with Lesch-Nyhan syndrome. Acta paediatrica (Oslo, Norway : 1992) 20061101
Molecular analysis of base damage clustering associated with a site-specific radiation-induced DNA double-strand break. Radiation research 20061101
SSCP analysis of the P2 purine transporter TcoAT1 gene of Trypanosoma congolense leads to a simple PCR-RFLP test allowing the rapid identification of diminazene resistant stocks. Acta tropica 20061101
Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance. PLoS biology 20061101
[Killing effect of PNP/MeP-dR suicide gene system driven by an AFP promoter AF0.3 on AFP-positive hepatoma cells]. Ai zheng = Aizheng = Chinese journal of cancer 20061101
Target DNA structure plays a critical role in RAG transposition. PLoS biology 20061101
2-CdA in the treatment of hairy cell leukemia: a review of long-term follow-up. Leukemia & lymphoma 20061101
Chronic lymphocytic leukemia: current and emerging treatment approaches. Clinical advances in hematology & oncology : H&O 20061101
First joint italian-german purine club meeting 'progress in purinergic receptor pharmacology and function'. Purinergic signalling 20061101
Roles of P2 receptors in glial cells: focus on astrocytes. Purinergic signalling 20061101
Signal transduction events induced by extracellular guanosine 5' triphosphate in excitable cells. Purinergic signalling 20061101
Guanosine effect on cholesterol efflux and apolipoprotein E expression in astrocytes. Purinergic signalling 20061101
Non-adenine based purines accelerate wound healing. Purinergic signalling 20061101
Recent advances in structure and function of cytosolic IMP-GMP specific 5'-nucleotidase II (cN-II). Purinergic signalling 20061101
Multiple determinants influence root colonization and induction of induced systemic resistance by Pseudomonas chlororaphis O6. Molecular plant pathology 20061101
Mouse transthyretin-related protein is a hydrolase which degrades 5-hydroxyisourate, the end product of the uricase reaction. Molecules and cells 20061031
Tautomerism in the guanyl radical. Journal of the American Chemical Society 20061025
Diagnosing AICA-ribosiduria by capillary electrophoresis. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061020
Cytostatic and antiviral 6-arylpurine ribonucleosides. Part 7: synthesis and evaluation of 6-substituted purine l-ribonucleosides. Bioorganic & medicinal chemistry letters 20061015
Heavy smoking and liver. World journal of gastroenterology 20061014
Structure of zebra fish HIUase: insights into evolution of an enzyme to a hormone transporter. Journal of molecular biology 20061013
ATP-consuming and ATP-generating enzymes secreted by pancreas. The Journal of biological chemistry 20061006
Simplified analogues of immucillin-G retain potent human purine nucleoside phosphorylase inhibitory activity. Journal of medicinal chemistry 20061005
9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1. Journal of medicinal chemistry 20061005
ATP potentiates neurotransmission in the rat trigeminal subnucleus caudalis. Neuroreport 20061002
TAT-mediated intracellular delivery of purine nucleoside phosphorylase corrects its deficiency in mice. The Journal of clinical investigation 20061002
Trypanosoma brucei: a survey of pyrimidine transport activities. Experimental parasitology 20061001
Synthesis and antiviral evaluation of alkoxyalkyl esters of acyclic purine and pyrimidine nucleoside phosphonates against HIV-1 in vitro. Antiviral research 20061001
EULAR evidence based recommendations for gout. Part II: Management. Report of a task force of the EULAR Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Annals of the rheumatic diseases 20061001
P2Y1 receptors mediate inhibitory purinergic neuromuscular transmission in the human colon. American journal of physiology. Gastrointestinal and liver physiology 20061001
Forodesine, an inhibitor of purine nucleoside phosphorylase, induces apoptosis in chronic lymphocytic leukemia cells. Blood 20061001
The paperclip triplex: understanding the role of apex residues in tight turns. Biophysical journal 20061001
Adenosine kinase from Cryptosporidium parvum. Molecular and biochemical parasitology 20061001
Rituximab combined with cladribine or with cladribine and cyclophosphamide in heavily pretreated patients with indolent lymphoproliferative disorders and mantle cell lymphoma. Cancer 20061001
Genotoxic effects in C57Bl/6J mice chronically exposed to arsenate in drinking water and modulation of the effects by low-selenium diet. Journal of toxicology and environmental health. Part A 20061001
The response of gastrointestinal microbiota to avilamycin, butyrate, and plant extracts in early-weaned pigs. Journal of animal science 20061001
Cladribine: an investigational immunomodulatory agent for multiple sclerosis. The Annals of pharmacotherapy 20061001
Clinical presentations and complications of hairy cell leukemia. Hematology/oncology clinics of North America 20061001
Splenectomy, interferon, and treatments of historical interest in hairy cell leukemia. Hematology/oncology clinics of North America 20061001
Purine analogues: rationale for development, mechanisms of action, and pharmacokinetics in hairy cell leukemia. Hematology/oncology clinics of North America 20061001
Pentostatin: impact on outcome in hairy cell leukemia. Hematology/oncology clinics of North America 20061001
Cladribine in hairy cell leukemia. Hematology/oncology clinics of North America 20061001
Immunotoxins in the treatment of refractory hairy cell leukemia. Hematology/oncology clinics of North America 20061001
Hairy cell leukemia: towards a curative strategy. Hematology/oncology clinics of North America 20061001
Transglutaminase 2 limits murine peritoneal acute gout-like inflammation by regulating macrophage clearance of apoptotic neutrophils. Arthritis and rheumatism 20061001
Drug evaluation: forodesine - PNP inhibitor for the treatment of leukemia, lymphoma and solid tumor. IDrugs : the investigational drugs journal 20061001
Enhanced killing of melanoma cells by simultaneously targeting Mcl-1 and NOXA. Cancer research 20061001
Back to the beginnings: an autobiography. Transfusion medicine reviews 20061001
Cytokine-purine interactions in traumatic stress, behavioral depression, and sickness. CNS & neurological disorders drug targets 20061001
External proficiency testing programmes in laboratory diagnoses of inherited metabolic disorders. Annals of the Academy of Medicine, Singapore 20061001
A kinetic, modeling and mechanistic re-analysis of thymidine phosphorylase and some related enzymes. Journal of enzyme inhibition and medicinal chemistry 20061001
Narrative review: initial management of newly diagnosed, early-stage chronic lymphocytic leukemia. Annals of internal medicine 20060919
Time-resolved photoelectron and photoion fragmentation spectroscopy study of 9-methyladenine and its hydrates: a contribution to the understanding of the ultrafast radiationless decay of excited DNA bases. Physical chemistry chemical physics : PCCP 20060914
Design, synthesis, and biophysical and biological evaluation of a series of pyrrolobenzodiazepine-poly(N-methylpyrrole) conjugates. Journal of medicinal chemistry 20060907
5'-O-tritylinosine and analogues as allosteric inhibitors of human thymidine phosphorylase. Journal of medicinal chemistry 20060907
Symptomatic hypoglycemia: an unusual side effect of oral purine analogues for treatment of ALL. Pediatric blood & cancer 20060901
Characterization of T-cell repertoire in hairy cell leukemia patients before and after recombinant immunotoxin BL22 therapy. Cancer immunology, immunotherapy : CII 20060901
Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation. Journal of cellular biochemistry 20060901
Activity and expression of ecto-5'-nucleotidase/CD73 are increased by thyroid hormones in vascular smooth muscle cells. Molecular and cellular biochemistry 20060901
Metabolism and ecology of purine alkaloids. Frontiers in bioscience : a journal and virtual library 20060901
The transthyretin-related protein: structural investigation of a novel protein family. Journal of structural biology 20060901
Synthesis and biological evaluation of carboacyclic nucleosides with (Z) and (E)-9-[4,4-bis(hydroxymethyl)]-2-butenyl side chain. Bioorganic & medicinal chemistry 20060901
Purine release from spinal cord microglia after elevation of calcium by glutamate. Molecular pharmacology 20060901
Toxoplasma gondii purine nucleoside phosphorylase biochemical characterization, inhibitor profiles, and comparison with the Plasmodium falciparum ortholog. The Journal of biological chemistry 20060901
Uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase. Neuroscience research 20060901
Biotransformation of adenine and cytokinins by the rhizobacterium Serratia proteamaculans. Phytochemistry 20060901
Gene expression for enzymes and transporters involved in regulating adenosine and inosine levels in rat forebrain neurons, astrocytes and C6 glioma cells. Journal of neuroscience research 20060901
Crystal structure of a non-discriminating glutamyl-tRNA synthetase. Journal of molecular biology 20060901
Effects of dairy cow diet forage proportion on duodenal nutrient supply and urinary purine derivative excretion. Journal of dairy science 20060901
Azathioprine in dermatology: the past, the present, and the future. Journal of the American Academy of Dermatology 20060901
Investigating the caffeine effects in the yeast Saccharomyces cerevisiae brings new insights into the connection between TOR, PKC and Ras/cAMP signalling pathways. Molecular microbiology 20060901
Alcohol consumption as a trigger of recurrent gout attacks. The American journal of medicine 20060901
Structure-activity relationship studies on the immune stimulatory effects of base-modified CpG toll-like receptor 9 agonists. ChemMedChem 20060901
Tris(1,9-diethyladeninium) triiodide diiodide. Acta crystallographica. Section C, Crystal structure communications 20060901
Designing siRNA that distinguish between genes that differ by a single nucleotide. PLoS genetics 20060901
Methotrexate enhances the antianabolic and antiproliferative effects of 5-aminoimidazole-4-carboxamide riboside. Molecular cancer therapeutics 20060901
Update on risk-stratified management for chronic lymphocytic leukemia. Leukemia & lymphoma 20060901
Treatment of recurrent Langerhans cell histiocytosis in children with 2-chlorodeoxyadenosine. Leukemia & lymphoma 20060901
Energetics of the failing heart: new insights using genetic modification in the mouse. Archives des maladies du coeur et des vaisseaux 20060901
P2X7 receptor expression levels determine lethal effects of a purine based danger signal in T lymphocytes. Cellular immunology 20060901
Asparaginase (native ASNase or pegylated ASNase) in the treatment of acute lymphoblastic leukemia. International journal of nanomedicine 20060901
Plant responses to extracellular nucleotides: Cellular processes and biological effects. Purinergic signalling 20060901
Integration of P2Y receptor-activated signal transduction pathways in G protein-dependent signalling networks. Purinergic signalling 20060901
P2 receptors in atherosclerosis and postangioplasty restenosis. Purinergic signalling 20060901
Increased 5-HT(3)-mediated signalling in pelvic afferent neurons from mice deficient in P2X(2) and/or P2X (3) receptor subunits. Purinergic signalling 20060901
Excitatory effect of ATP on rat area postrema neurons. Purinergic signalling 20060901
Nelarabine: a new purine analog in the treatment of hematologic malignancies. Reviews on recent clinical trials 20060901
Changes of purine and pyrimidine nucleotide biosynthesis during shoot initiation from epicotyl explants of white spruce (Picea glauca). Plant science : an international journal of experimental plant biology 20060901
Protein dynamics and catalysis: the problems of transition state theory and the subtlety of dynamic control. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20060829
Antitumor agents. 5. synthesis, structure-activity relationships, and biological evaluation of dimethyl-5H-pyridophenoxazin-5-ones, tetrahydro-5h-benzopyridophenoxazin-5-ones, and 5h-benzopyridophenoxazin-5-ones with potent antiproliferative activity. Journal of medicinal chemistry 20060824
Methotrexate used in combination with aminolaevulinic acid for photodynamic killing of prostate cancer cells. British journal of cancer 20060821
The neglected Pt-N(sulfonamido) bond in Pt chemistry. New fluorophore-containing Pt(II) complexes useful for assessing Pt(II) interactions with biomolecules. Inorganic chemistry 20060821
Multiple endoplasmic reticulum-to-nucleus signaling pathways coordinate phospholipid metabolism with gene expression by distinct mechanisms. The Journal of biological chemistry 20060818
C6-substituted analogues of 8-azanebularine: probes of an RNA-editing enzyme active site. Organic letters 20060817
The development of novel C-2, C-8, and N-9 trisubstituted purines as inhibitors of TNF-alpha production. Bioorganic & medicinal chemistry letters 20060815
Synthesis and biological evaluation of purine derivatives incorporating metal chelating ligands as HIV integrase inhibitors. Bioorganic & medicinal chemistry 20060815
Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents. Bioorganic & medicinal chemistry letters 20060815
H-bonding-directed self-assembly of synthetic copolymers containing nucleobases: organization and colloidal fusion in a noncompetitive solvent. Langmuir : the ACS journal of surfaces and colloids 20060815
The GT to GC single nucleotide polymorphism at the beginning of an alternative exon 2C of human MTH1 gene confers an amino terminal extension that functions as a mitochondrial targeting signal. Journal of molecular medicine (Berlin, Germany) 20060801
A survey of mRNA sequences with a non-AUG start codon in RefSeq database. Journal of biomolecular structure & dynamics 20060801
Current treatment options in hairy cell leukemia and hairy cell leukemia variant. Cancer treatment reviews 20060801
AUG-proximal nucleotides regulate protein synthesis in Leishmania tropica. Molecular microbiology 20060801
Single-agent purine analogues for the treatment of chronic lymphocytic leukaemia: a systematic review and meta-analysis. Cancer treatment reviews 20060801
Nucleoside transporters: from scavengers to novel therapeutic targets. Trends in pharmacological sciences 20060801
Comparative proteomic analysis of Staphylococcus aureus strains with differences in resistance to the cell wall-targeting antibiotic vancomycin. Proteomics 20060801
The adenosine system selectively inhibits TLR-mediated TNF-alpha production in the human newborn. Journal of immunology (Baltimore, Md. : 1950) 20060801
Mutational analysis of the promoter recognized by Chlamydia and Escherichia coli sigma(28) RNA polymerase. Journal of bacteriology 20060801
Enhanced separation of purine and pyrimidine bases using carboxylic multiwalled carbon nanotubes as additive in capillary zone electrophoresis. Electrophoresis 20060801
Vitamin B12 reduces ribavirin-induced genotoxicity in phytohemaglutinin-stimulated human lymphocytes. The Tohoku journal of experimental medicine 20060801
Fludarabine in chronic lymphocytic leukaemia. Expert opinion on pharmacotherapy 20060801
[Synthetic study of nucleoside antibiotics]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060801
Bioinformatic analysis of Helicobacter pylori XGPRTase: a potential therapeutic target. Helicobacter 20060801
Chronic lymphocytic leukemia: diagnosis and treatment. Mayo Clinic proceedings 20060801
Proteomic analysis of protein expression in Streptococcus pneumoniae in response to temperature shift. Journal of microbiology (Seoul, Korea) 20060801
Hairy-cell leukaemia: first-line treatment with cladribine or pentostatin. Prescrire international 20060801
[Advances in the study of nucleoside antiviral drugs]. Yao xue xue bao = Acta pharmaceutica Sinica 20060801
Nucleotide-mimetic synthetic ligands for DNA-recognizing enzymes One-step purification of Pfu DNA polymerase. Journal of chromatography. A 20060728
Mutagenesis by exocyclic alkylamino purine adducts in Escherichia coli. Mutation research 20060725
Purine antagonists for chronic lymphocytic leukaemia. The Cochrane database of systematic reviews 20060719
Amplified oligonucleotide sensing in microliter volumes containing copper ions by solution streaming. Analytical chemistry 20060715
Activation of the purine salvage pathway in mononuclear cells of cardiac recipients treated with mycophenolate mofetil. Transplantation 20060715
Engineering of a single conserved amino acid residue of herpes simplex virus type 1 thymidine kinase allows a predominant shift from pyrimidine to purine nucleoside phosphorylation. The Journal of biological chemistry 20060714
MTH1, an oxidized purine nucleoside triphosphatase, prevents the cytotoxicity and neurotoxicity of oxidized purine nucleotides. DNA repair 20060713
Regulation of folate-mediated one-carbon metabolism by 10-formyltetrahydrofolate dehydrogenase. The Journal of biological chemistry 20060707
Post-reperfusion myocardial infarction: long-term survival improvement using adenosine regulation with acadesine. Journal of the American College of Cardiology 20060704
Mycophenolate mofetil is a highly effective and safe immunosuppressive agent for the treatment of uveitis : a retrospective analysis of 106 patients. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060701
Symbiotic abilities of Sinorhizobium fredii with modified expression of purL. Applied microbiology and biotechnology 20060701
Hepatic cytochrome P-450 reductase-null mice show reduced transcriptional response to quercetin and reveal physiological homeostasis between jejunum and liver. American journal of physiology. Gastrointestinal and liver physiology 20060701
Leishmania donovani singly deficient in HGPRT, APRT or XPRT are viable in vitro and within mammalian macrophages. Molecular and biochemical parasitology 20060701
Deoxyribonucleic acid damage and spontaneous mutagenesis in the thyroid gland of rats and mice. Endocrinology 20060701
Oxidative stress and heat-shock responses in Desulfovibrio vulgaris by genome-wide transcriptomic analysis. Antonie van Leeuwenhoek 20060701
Recent diuretic use and the risk of recurrent gout attacks: the online case-crossover gout study. The Journal of rheumatology 20060701
Purine-induced expression of urate oxidase and enzyme activity in Atlantic salmon (Salmo salar). Cloning of urate oxidase liver cDNA from three teleost species and the African lungfish Protopterus annectens. The FEBS journal 20060701
Long-term mizoribine intermittent pulse therapy for young patients with flare of lupus nephritis. Pediatric nephrology (Berlin, Germany) 20060701
Acute renal failure due to bilateral xanthine urolithiasis in a boy with Lesch-Nyhan syndrome. Pediatric nephrology (Berlin, Germany) 20060701
Cell biology of molybdenum. Biochimica et biophysica acta 20060701
Molecular simulations of cotranslational protein folding: fragment stabilities, folding cooperativity, and trapping in the ribosome. PLoS computational biology 20060701
Bis(6-thioxo-1,6-dihydropurinium) tetrachlorozincate(II). Acta crystallographica. Section C, Crystal structure communications 20060701
Different nucleobase orientations in two cyclic 2',3'-phosphates of purine ribonucleosides: Et(3)NH(2',3'-cAMP) and Et(3)NH(2',3'-cGMP)xH(2)O. Acta crystallographica. Section C, Crystal structure communications 20060701
Interrelationship between uremic toxicity and oxidative stress. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20060701
Uncoupling of ATP-mediated calcium signaling and dysregulated interleukin-6 secretion in dendritic cells by nanomolar thimerosal. Environmental health perspectives 20060701
Circadian rhythmicity by autocatalysis. PLoS computational biology 20060701
Targeting Hsp90 for the treatment of cancer. Current opinion in drug discovery & development 20060701
Reduced-intensity transplantation for lymphoma. Current treatment options in oncology 20060701
Fine-tuning modulation of myenteric motoneurons by endogenous adenosine: on the role of secreted adenosine deaminase. Autonomic neuroscience : basic & clinical 20060630
The crystal structure of the transthyretin-like protein from Salmonella dublin, a prokaryote 5-hydroxyisourate hydrolase. Journal of molecular biology 20060623
Computer modelling of antifolate inhibition of folate metabolism using hybrid functional petri nets. Journal of theoretical biology 20060621
Phosphate activation in the ground state of purine nucleoside phosphorylase. Journal of the American Chemical Society 20060621
Thermodynamics of the purine nucleotide cycle. Biophysical chemistry 20060620
Intercalating polycyclic aromatic hydrocarbon-DNA adducts poison DNA religation by Vaccinia topoisomerase and act as roadblocks to digestion by exonuclease III. Biochemistry 20060620
Sensitivity of markers of DNA stability and DNA repair activity to folate supplementation in healthy volunteers. British journal of cancer 20060619
The purines: potent and versatile small molecule inhibitors and modulators of key biological targets. Bioorganic & medicinal chemistry 20060615
DNA and LNA oligonucleotides containing N2'-functionalised derivatives of 2'-amino-2'-deoxyuridine. Bioorganic & medicinal chemistry letters 20060615
Effect of various pyrimidines possessing the 1-[(2-hydroxy-1-(hydroxymethyl)ethoxy)methyl] moiety, able to mimic natural 2'-deoxyribose, on wild-type and mutant hepatitis B virus replication. Journal of medicinal chemistry 20060615
GENTEX, a general multiscale model for in vivo tissue exchanges and intraorgan metabolism. Philosophical transactions. Series A, Mathematical, physical, and engineering sciences 20060615
Structure-activity relationship for nucleoside analogs as inhibitors or substrates of adenosine kinase from Mycobacterium tuberculosis. I. Modifications to the adenine moiety. Biochemical pharmacology 20060614
A conditional mutant deficient in hypoxanthine-guanine phosphoribosyltransferase and xanthine phosphoribosyltransferase validates the purine salvage pathway of Leishmania donovani. The Journal of biological chemistry 20060609
Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain. Journal of molecular biology 20060609
C5'-adenosinyl radical cyclization. A stereochemical investigation. The Journal of organic chemistry 20060609
Cross-coupling reactions of unprotected halopurine bases, nucleosides, nucleotides and nucleoside triphosphates with 4-boronophenylalanine in water. Synthesis of (purin-8-yl)- and (purin-6-yl)phenylalanines. Organic & biomolecular chemistry 20060607
Transition state analogue discrimination by related purine nucleoside phosphorylases. Journal of the American Chemical Society 20060607
Modified nucleosides: an accurate tumour marker for clinical diagnosis of cancer, early detection and therapy control. British journal of cancer 20060605
Transition-state complex of the purine-specific nucleoside hydrolase of T. vivax: enzyme conformational changes and implications for catalysis. Journal of molecular biology 20060602
Purification and characterization of a novel mammalian endoribonuclease. Journal of cellular biochemistry 20060601
In silico prediction of the glycosomal enzymes of Leishmania major and trypanosomes. Molecular and biochemical parasitology 20060601
Involvement of adenosine in the neurobiology of schizophrenia and its therapeutic implications. Progress in neuro-psychopharmacology & biological psychiatry 20060601
Comprehensive detection of disorders of purine and pyrimidine metabolism by HPLC with electrospray ionization tandem mass spectrometry. Clinical chemistry 20060601
Mitochondrial one-carbon metabolism is adapted to the specific needs of yeast, plants and mammals. BioEssays : news and reviews in molecular, cellular and developmental biology 20060601
Structures of regulatory elements in mRNAs. Current opinion in structural biology 20060601
Biomarkers signal contaminant effects on the organs of English sole (Parophrys vetulus) from Puget Sound. Environmental health perspectives 20060601
Withdrawal. Changes in purine metabolism and production of oxygen free radicals by intermittent partial umbilical cord occlusion in chronically instrumented fetal lambs. The journal of obstetrics and gynaecology research 20060601
Nucleotide mutations in purA gene and pur operon promoter discovered in guanosine- and inosine-producing Bacillus subtilis strains. Biotechnology letters 20060601
Parametric alignment of Drosophila genomes. PLoS computational biology 20060601
Derivation and characterization of a monoclonal antibody against human glycinamide ribonucleotide formyltransferase. Hybridoma (2005) 20060601
[Molecular cloning and expression analysis of swamp eel (Monopterus albus) Hprt]. Yi chuan = Hereditas 20060601
Involvement of LuxR, a quorum sensing regulator in Vibrio harveyi, in the promotion of metabolic genes: argA, purM, lysE and rluA. Biochimica et biophysica acta 20060601
New developments in the epidemiology and genetics of gout. Current rheumatology reports 20060601
Ecto-5'-nucleotidase: Structure function relationships. Purinergic signalling 20060601
Physiological roles for ecto-5'-nucleotidase (CD73). Purinergic signalling 20060601
Modulation of purinergic signaling by NPP-type ectophosphodiesterases. Purinergic signalling 20060601
E-NTPDases in human airways: Regulation and relevance for chronic lung diseases. Purinergic signalling 20060601
The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance. Purinergic signalling 20060601
Expressed sequence tag (EST) analysis of the erythrocytic stages of Babesia bovis. Veterinary parasitology 20060531
The extraordinary specificity of xanthine phosphoribosyltransferase from Bacillus subtilis elucidated by reaction kinetics, ligand binding, and crystallography. Biochemistry 20060530
The transmembrane domain provides nucleotide binding specificity to the bacterial conjugation protein TrwB. FEBS letters 20060529
A general synthesis of C6-azolyl purine nucleosides. Angewandte Chemie (International ed. in English) 20060526
Structure and synthesis of 6-(substituted-imidazol-1-yl)purines: versatile substrates for regiospecific alkylation and glycosylation at N9. The Journal of organic chemistry 20060526
Interaction energies for the purine inhibitor roscovitine with cyclin-dependent kinase 2: correlated ab initio quantum-chemical, DFT and empirical calculations. Chemistry (Weinheim an der Bergstrasse, Germany) 20060524
2,6-disubstituted and 2,6,8-trisubstituted purines as adenosine receptor antagonists. Journal of medicinal chemistry 20060518
Purine and folate metabolism as a potential target of sex-specific nutrient allocation in Drosophila and its implication for lifespan-reproduction tradeoff. Physiological genomics 20060516
Role of the Cys18-Cys274 disulfide bond and of the third extracellular loop in the constitutive activation and internalization of angiotensin II type 1 receptor. Regulatory peptides 20060515
Microanalysis of oligodeoxynucleotides by cathodic stripping voltammetry at amalgam-alloy surfaces in the presence of copper ions. Talanta 20060515
The lack of A2A adenosine receptors diminishes the reinforcing efficacy of cocaine. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060501
Control by cytokinins of the cellular behavior in the plate meristem of zucchini cotyledons. Planta 20060501
Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine. International journal of cancer 20060501
Characterization of novel Na+-dependent nucleobase transport systems at the blood-testis barrier. American journal of physiology. Endocrinology and metabolism 20060501
Postnatal development of P2 receptors in the murine gastrointestinal tract. Neuropharmacology 20060501
DNA tracts composed of only two bases concentrate in gene promoters. Genomics 20060501
Suboptimal CD4 gains in HIV-infected patients receiving didanosine plus tenofovir. The Journal of antimicrobial chemotherapy 20060501
Genotoxicity of chloroquine in rat liver cells: protective role of free radical scavengers. Cell biology and toxicology 20060501
Delineation of the motor disorder of Lesch-Nyhan disease. Brain : a journal of neurology 20060501
Identification of inhibitors of ribozyme self-cleavage in mammalian cells via high-throughput screening of chemical libraries. RNA (New York, N.Y.) 20060501
New agents in chronic lymphocytic leukemia. Current treatment options in oncology 20060501
Caffeine biosynthesis and adenine metabolism in transgenic Coffea canephora plants with reduced expression of N-methyltransferase genes. Phytochemistry 20060501
Transport of nucleosides across the Plasmodium falciparum parasite plasma membrane has characteristics of PfENT1. Molecular microbiology 20060501
Probing the mechanism of purine nucleoside phosphorylase by steady-state kinetic studies and ligand binding characterization determined by fluorimetric titrations. Biochimica et biophysica acta 20060501
Expression, purification, crystallization and preliminary X-ray diffraction analysis of human phosphoribosyl pyrophosphate synthetase 1 (PRS1). Acta crystallographica. Section F, Structural biology and crystallization communications 20060501
[Efficacy of rituximab in hairy cell leukemia]. Presse medicale (Paris, France : 1983) 20060501
Iterative reconstruction of transcriptional regulatory networks: an algorithmic approach. PLoS computational biology 20060501
Pharmacological and clinical studies on purine nucleoside analogs--new anticancer agents. Mini reviews in medicinal chemistry 20060501
The purine metabolism of human erythrocytes. Biochemistry. Biokhimiia 20060501
Nitrogenous compounds of interest in clinical nutrition. Nutricion hospitalaria 20060501
The effect of acidosis on adenosine release from cultured rat forebrain neurons. Brain research 20060412
Repair of thymine glycol by hNth1 and hNeil1 is modulated by base pairing and cis-trans epimerization. DNA repair 20060408
Schwann cells in rat vascular autonomic nerves activated via purinergic receptors. Neuroreport 20060403
MTH1, an oxidized purine nucleoside triphosphatase, protects the dopamine neurons from oxidative damage in nucleic acids caused by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Cell death and differentiation 20060401
Trypanosoma cruzi: Mutations in the 3' untranslated region of calmodulin gene are specific for lineages T. cruzi I, T. cruzi II, and the Zymodeme III isolates. Experimental parasitology 20060401
O6-(4-bromothenyl)guanine (PaTrin-2), a novel inhibitor of O6-alkylguanine DNA alkyl-transferase, increases the inhibitory activity of temozolomide against human acute leukaemia cells in vitro. Pharmacological research 20060401
Insight into the CSA tensors of nucleobase carbons in RNA polynucleotides from solution measurements of residual CSA: towards new long-range orientational constraints. Journal of magnetic resonance (San Diego, Calif. : 1997) 20060401
AtAAH encodes a protein with allantoate amidohydrolase activity from Arabidopsis thaliana. Planta 20060401
Solution structure of an informationally complex high-affinity RNA aptamer to GTP. RNA (New York, N.Y.) 20060401
Pentostatin, cyclophosphamide, and rituximab is an active, well-tolerated regimen for patients with previously treated chronic lymphocytic leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060401
Mitochondrial uncoupling proteins: new insights from functional and proteomic studies. Free radical biology & medicine 20060401
Purine analogue combinations for indolent lymphomas. Seminars in hematology 20060401
Pentostatin for the treatment of indolent lymphoproliferative disorders. Seminars in hematology 20060401
Role of single-agent purine analogues in therapy of peripheral T-cell lymphomas. Seminars in hematology 20060401
Purine analogues in advanced T-cell lymphoid malignancies. Seminars in hematology 20060401
The role of purine analogues in low-intensity regimens with allogeneic hematopoietic stem cell transplantation. Seminars in hematology 20060401
Purine analogue-based chemotherapy regimens for second-line therapy in patients with chronic lymphocytic leukemia. Seminars in hematology 20060401
Purine analogue-based chemotherapy regimens for patients with previously untreated B-chronic lymphocytic leukemia. Seminars in hematology 20060401
Genes encoding ribonucleoside hydrolase 1 and 2 from Corynebacterium ammoniagenes. Microbiology (Reading, England) 20060401
Pentostatin and purine analogs for indolent lymphoid malignancies. Future oncology (London, England) 20060401
Structure of SAICAR synthase from Thermotoga maritima at 2.2 angstroms reveals an unusual covalent dimer. Acta crystallographica. Section F, Structural biology and crystallization communications 20060401
Reaction mechanisms of riboflavin triplet state with nucleic acid bases. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20060401
Linkage analysis with an interbreed backcross maps Dalmatian hyperuricosuria to CFA03. Mammalian genome : official journal of the International Mammalian Genome Society 20060401
Mutagenesis and carcinogenesis caused by the oxidation of nucleic acids. Biological chemistry 20060401
Autoimmune complications of chronic lymphocytic leukemia. Seminars in oncology 20060401
Infectious complications of chronic lymphocytic leukemia. Seminars in oncology 20060401
Practical strategies for discovering regulatory DNA sequence motifs. PLoS computational biology 20060401
Novel therapeutic strategies with alemtuzumab for chronic lymphocytic leukemia. Seminars in oncology 20060401
Strategies in the management of alemtuzumab-related side effects. Seminars in oncology 20060401
Intracellular delivery of purine nucleoside phosphorylase (PNP) fused to protein transduction domain corrects PNP deficiency in vitro. Cellular immunology 20060401
A novel-type substrate-selectivity filter and ER-exit determinants in the UapA purine transporter. Journal of molecular biology 20060331
Selective magnesiation of chloro-iodopurines: an efficient approach to new purine derivatives. Organic letters 20060330
Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases. Cancer letters 20060328
Consecutive GA pairs stabilize medium-size RNA internal loops. Biochemistry 20060328
The PnrA (Tp0319; TmpC) lipoprotein represents a new family of bacterial purine nucleoside receptor encoded within an ATP-binding cassette (ABC)-like operon in Treponema pallidum. The Journal of biological chemistry 20060324
Syntheses and bio-activities of the L-enantiomers of two potent transition state analogue inhibitors of purine nucleoside phosphorylases. Organic & biomolecular chemistry 20060321
Fluorescence energy transfer studies of human deoxycytidine kinase: role of cysteine 185 in the conformational changes that occur upon substrate binding. Biochemistry 20060321
Structure of purine-purine mispairs during misincorporation and extension by Escherichia coli DNA polymerase I. Biochemistry 20060321
The crystal structure of 5'-deoxy-5'-methylthioadenosine phosphorylase II from Sulfolobus solfataricus, a thermophilic enzyme stabilized by intramolecular disulfide bonds. Journal of molecular biology 20060317
Synthesis and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methyl purine nucleosides as inhibitors of hepatitis C virus RNA replication. Bioorganic & medicinal chemistry letters 20060315
Nucleotide-binding sites in the voltage-dependent anion channel: characterization and localization. The Journal of biological chemistry 20060303
Effects of halogenated WNA derivatives on sequence dependency for expansion of recognition sequences in non-natural-type triplexes. The Journal of organic chemistry 20060303
Monitoring of antioxidant properties of uric acid in humans for a consideration measuring of levels of allantoin in plasma by liquid chromatography. Clinica chimica acta; international journal of clinical chemistry 20060301
Genetic manipulation of two fowlpox virus late transcriptional regulatory elements influences their ability to direct expression of foreign genes. Virus research 20060301
Synthesis and biological evaluation of 9-(5',5'-difluoro-5'-phosphonopentyl)guanine derivatives for PNP-inhibitors. Bioorganic & medicinal chemistry 20060301
Cysteine-accessibility analysis of transmembrane domains 11-13 of human concentrative nucleoside transporter 3. The Biochemical journal 20060301
The genes induced by signal transducer and activators of transcription (STAT)3 and STAT5 in mammary epithelial cells define the roles of these STATs in mammary development. Molecular endocrinology (Baltimore, Md.) 20060301
Pharmacologic characterization of intrinsic mechanisms controlling tone and relaxation of porcine lower esophageal sphincter. The Journal of pharmacology and experimental therapeutics 20060301
The purine synthesis gene Prat2 is required for Drosophila metamorphosis, as revealed by inverted-repeat-mediated RNA interference. Genetics 20060301
Molecular, biochemical, and genetic characterization of a female patient with Lesch-Nyhan disease. Molecular genetics and metabolism 20060301
Intense exercise induces the degradation of adenine nucleotide and purine nucleotide synthesis via de novo pathway in the rat liver. European journal of applied physiology 20060301
Uric acid, a nucleic acid degradation product, down-regulates dsRNA-triggered arthritis. Journal of leukocyte biology 20060301
Determination of acid-base dissociation constants of amino- and guanidinopurine nucleotide analogs and related compounds by capillary zone electrophoresis. Electrophoresis 20060301
Uric acid crystals in the semen of a patient with symptoms of chronic prostatitis. Fertility and sterility 20060301
Advances in the treatment of Waldenström's macroglobulinemia. Expert review of anticancer therapy 20060301
Treatment of gastric mucosa-associated lymphoid tissue lymphoma: Helicobacter pylori eradication and beyond. Expert review of anticancer therapy 20060301
Pathophysiology and therapeutic potential of purinergic signaling. Pharmacological reviews 20060301
Specific functional interactions of nucleotides at key -3 and +4 positions flanking the initiation codon with components of the mammalian 48S translation initiation complex. Genes & development 20060301
Genome update: purine strand bias in 280 bacterial genomes. Microbiology (Reading, England) 20060301
Pentose phosphates in nucleoside interconversion and catabolism. The FEBS journal 20060301
Human cytochrome P450 reductase can act as a source of endogenous oxidative DNA damage and genetic instability. Free radical biology & medicine 20060301
Gemcitabine and atrial fibrillation: a rare manifestation of chemotherapy toxicity. Anti-cancer drugs 20060301
Integration of ruminal metabolism in dairy cattle. Journal of dairy science 20060301
Structure-guided engineering of xylitol dehydrogenase cosubstrate specificity. Structure (London, England : 1993) 20060301
[Correlations between serine hydroxymethyltransferase1 C1420T polymorphisms and susceptibilities to esophageal squamous cell carcinoma and gastric cardiac adenocarcinoma]. Ai zheng = Aizheng = Chinese journal of cancer 20060301
A third approach to gene prediction suggests thousands of additional human transcribed regions. PLoS computational biology 20060301
Phosphate alkylation in different DNA substrates: the role of local DNA sequence and electrophile character in determining the nonrandom nature of phosphotriester adduct formation. Chemical research in toxicology 20060301
Synthesis and antiviral evaluation of novel open-chain analogues of neplanocin A. Nucleosides, nucleotides & nucleic acids 20060301
Effects of allopurinol on beer-induced increases in plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine). Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060301
Advances in the treatment of chronic lymphocytic leukemia. Current hematologic malignancy reports 20060301
Evaluation of urinary abnormalities in nephrolithiasis patients from Marathwada region. Indian journal of clinical biochemistry : IJCB 20060301
A clinical assessment of direct electrochemical urate measurements. Talanta 20060227
1,3-Alternate 25,27-dibenzoiloxy-26,28-bis-[3-propyloxy]-calix[4]arene-bonded silica gel as a new type of HPLC stationary phase. Talanta 20060227
Bacterial small-molecule signaling pathways. Science (New York, N.Y.) 20060224
Heroin affects purine nucleotides catabolism in rats in vivo. Life sciences 20060223
Supramolecular architectures assembled by the interaction of purine nucleobases with metal-oxalato frameworks. Non-covalent stabilization of the 7H-adenine tautomer in the solid-state. Dalton transactions (Cambridge, England : 2003) 20060221
Platinum(II)-mediated coupling reactions of acetonitrile with the exocyclic nitrogen of 9-methyladenine and 1-methylcytosine. Synthesis, NMR characterization, and X-ray structures of new azametallacycle complexes. Inorganic chemistry 20060220
Improved HPLC method for the simultaneous determination of allantoin, uric acid and creatinine in cattle urine. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060217
Regulation of de novo purine biosynthesis by methenyltetrahydrofolate synthetase in neuroblastoma. The Journal of biological chemistry 20060217
Effect of allopurinol on brain adenosine levels during hypoxia in newborn piglets. Brain research 20060216
How I treat refractory CLL. Blood 20060215
Synthesis and biological evaluation of phosphonated carbocyclic 2'-oxa-3'-aza-nucleosides. Bioorganic & medicinal chemistry 20060215
Stochastic entropy QSAR for the in silico discovery of anticancer compounds: prediction, synthesis, and in vitro assay of new purine carbanucleosides. Bioorganic & medicinal chemistry 20060215
Structural investigation of bilayers formed by 1-palmitoyl-2-oleoylphosphatidylnucleosides. Biophysical journal 20060215
Unique properties of purine/pyrimidine asymmetric PNA.DNA duplexes: differential stabilization of PNA.DNA duplexes by purines in the PNA strand. Biophysical journal 20060215
The nucleotide derivatives inosine and inosinic acid inhibit intestinal absorption of mizoribine in rats. European journal of pharmacology 20060215
MTH1, an oxidized purine nucleoside triphosphatase, suppresses the accumulation of oxidative damage of nucleic acids in the hippocampal microglia during kainate-induced excitotoxicity. The Journal of neuroscience : the official journal of the Society for Neuroscience 20060208
Sequence dependence of the stability of RNA hairpin molecules with six nucleotide loops. Biochemistry 20060207
Crystal structure of human guanosine monophosphate reductase 2 (GMPR2) in complex with GMP. Journal of molecular biology 20060203
Synthesis and conformational analysis of new cyclobutane-fused nucleosides. Organic letters 20060202
Plant uncoupling protein in mitochondria from aged-dehydrated slices of Jerusalem artichoke tubers becomes sensitive to superoxide and to hydrogen peroxide without increase in protein level. Biochimie 20060201
Thymosin beta4 induces a conformational change in actin monomers. Biophysical journal 20060201
Substrate specificity of N-methyltransferase involved in purine alkaloids synthesis is dependent upon one amino acid residue of the enzyme. Molecular genetics and genomics : MGG 20060201
Activation of ERK1/2 by extracellular nucleotides in macrophages is mediated by multiple P2 receptors independently of P2X7-associated pore or channel formation. British journal of pharmacology 20060201
Zinc(II) complexes with potent cyclin-dependent kinase inhibitors derived from 6-benzylaminopurine: synthesis, characterization, X-ray structures and biological activity. Journal of inorganic biochemistry 20060201
Immunophenotypic variations in hairy cell leukemia. American journal of clinical pathology 20060201
Structure of Toxoplasma gondii adenosine kinase in complex with an ATP analog at 1.1 angstroms resolution. Acta crystallographica. Section D, Biological crystallography 20060201
Effects of malate on diet digestibility, microbial protein synthesis, plasma metabolites, and performance of growing lambs fed a high-concentrate diet. Journal of animal science 20060201
Transformation and progression of Waldenström's macroglobulinemia following cladribine therapy in two cases: natural evolution or iatrogenic causation? American journal of hematology 20060201
Homocysteine accumulation causes a defect in purine biosynthesis: further characterization of Schizosaccharomyces pombe methionine auxotrophs. Microbiology (Reading, England) 20060201
Inhibition of adenosine kinase by phosphonate and bisphosphonate derivatives. Molecular and cellular biochemistry 20060201
Adenosine receptors: promising targets for the development of novel therapeutics and diagnostics for asthma. Fundamental & clinical pharmacology 20060201
Activation of P2Y receptor enhances high-molecular compound absorption from rat ileum. The Journal of pharmacy and pharmacology 20060201
[Spicamycin derivative]. Nihon rinsho. Japanese journal of clinical medicine 20060201
NMR structures of damaged DNA. Chemical reviews 20060201
Heterologous expression of membrane and soluble proteins derepresses GCN4 mRNA translation in the yeast Saccharomyces cerevisiae. Eukaryotic cell 20060201
Clinical experience with pemetrexed in breast cancer. Seminars in oncology 20060201
Ratiometric fluorescence detection of pyrimidine/purine transversion by using a 2-amino-1,8-naphthyridine derivative. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060201
[Urinary stone disease indicating genetic background]. Nihon rinsho. Japanese journal of clinical medicine 20060201
T-cell activation via CD26 and caveolin-1 in rheumatoid synovium. Modern rheumatology 20060201
Isolation and characterization of promoters from Lactococcus lactis ssp. cremoris LM0230. Food microbiology 20060201
NMR imino proton exchange experiments on duplex DNA primarily monitor the opening of purine bases. Journal of the American Chemical Society 20060125
Insight into catalytically relevant correlated motions in human purine nucleoside phosphorylase. The journal of physical chemistry. A 20060119
Benzoderivatives of nucleic acid bases as modified DNA building blocks. The journal of physical chemistry. A 20060119
Ground-state interactions of spermine-substituted naphthalimides with mononucleotides. The journal of physical chemistry. B 20060119
Mechanistic mathematical modelling of mercaptopurine effects on cell cycle of human acute lymphoblastic leukaemia cells. British journal of cancer 20060116
Two- and three-dimensional quantitative structure-activity relationships for a series of purine nucleoside phosphorylase inhibitors. Bioorganic & medicinal chemistry 20060115
A retrospective comparison of three sequential groups of patients with Recurrent/Refractory chronic lymphocytic leukemia treated with fludarabine-based regimens. Cancer 20060115
Uncoupling protein 1 affects the yeast mitoproteome and oxygen free radical production. Free radical biology & medicine 20060115
Purine P1 receptor-dependent immunostimulatory effects of antiviral acyclic analogues of adenine and 2,6-diaminopurine. European journal of pharmacology 20060113
7-Functionalized 7-deazapurine ribonucleosides related to 2-aminoadenosine, guanosine, and xanthosine: glycosylation of pyrrolo[2,3-d]pyrimidines with 1-O-acetyl-2,3,5-tri-O-benzoyl-D-ribofuranose. The Journal of organic chemistry 20060106
N6-Cyclohexyl-adenosine but not adenosine is a modulator of teleost fish innate immune activities. Developmental and comparative immunology 20060101
Purine and pyrimidine metabolism and electrocortical brain activity during hypotension in near-term lambs. Biology of the neonate 20060101
A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems. Molecular pharmacology 20060101
Metabolic homeostasis in the human erythrocyte: in silico analysis. Bio Systems 20060101
Transition state analysis of adenosine nucleosidase from yellow lupin (Lupinus luteus). Phytochemistry 20060101
Update on ureide degradation in legumes. Journal of experimental botany 20060101
Effect of long-term phosphate starvation on the levels and metabolism of purine nucleotides in suspension-cultured Catharanthus roseus cells. Phytochemistry 20060101
Plasma concentrations and urinary excretion of purine bases (uric acid, hypoxanthine, and xanthine) and oxypurinol after rigorous exercise. Metabolism: clinical and experimental 20060101
Conserved and variable functions of the sigmaE stress response in related genomes. PLoS biology 20060101
Decreased GTP-stimulated adenylyl cyclase activity in HPRT-deficient human and mouse fibroblast and rat B103 neuroblastoma cell membranes. Journal of neurochemistry 20060101
Concomitant hairy cell and acute myeloid leukemia. European journal of haematology 20060101
A folate-dependent metabolite in amniotic fluid from pregnancies with normal or trisomy 21 chromosomes. Fetal diagnosis and therapy 20060101
Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase. Arthritis research & therapy 20060101
Combining infliximab with methotrexate for the induction and maintenance of remission in refractory Crohn's disease: a controlled pilot study. European journal of gastroenterology & hepatology 20060101
The combination of sulfinosine and 8-Cl-cAMP induces synergistic cell growth inhibition of the human neuroblastoma cell line in vitro. Investigational new drugs 20060101
Stepwise translocation of Dpo4 polymerase during error-free bypass of an oxoG lesion. PLoS biology 20060101
Design and cloning strategies for constructing shRNA expression vectors. BMC biotechnology 20060101
Early-onset autoimmune hemolytic anemia after cladribine therapy for Waldenström's macroglobulinemia. Transfusion 20060101
Analysis of and function predictions for previously conserved hypothetical or putative proteins in Blochmannia floridanus. BMC microbiology 20060101
Chronic lymphocytic leukemia: recent advances in diagnosis and treatment. The oncologist 20060101
Purmorphamine activates the Hedgehog pathway by targeting Smoothened. Nature chemical biology 20060101
Metabolic pathways variability and sequence/networks comparisons. BMC bioinformatics 20060101
Effects of a fenofibrate/losartan combination on the plasma concentration and urinary excretion of purine bases. International journal of clinical pharmacology and therapeutics 20060101
Effect and mechanism of total saponin of Dioscorea on animal experimental hyperuricemia. The American journal of Chinese medicine 20060101
Identification of metabolic system parameters using global optimization methods. Theoretical biology & medical modelling 20060101
Fludarabine induced autoimmune haemolytic anaemia in a patient with chronic lymphocytic leukaemia. JPMA. The Journal of the Pakistan Medical Association 20060101
BIOZON: a system for unification, management and analysis of heterogeneous biological data. BMC bioinformatics 20060101
Structural basis of Src tyrosine kinase inhibition with a new class of potent and selective trisubstituted purine-based compounds. Chemical biology & drug design 20060101
Abnormal turning behaviour, GABAergic inhibition and the degeneration of astrocytes in ovine Tribulus terrestris motor neuron disease. Australian veterinary journal 20060101
Common features and interesting differences in transcriptional responses to secretion stress in the fungi Trichoderma reesei and Saccharomyces cerevisiae. BMC genomics 20060101
Integrating protein structures and precomputed genealogies in the Magnum database: examples with cellular retinoid binding proteins. BMC bioinformatics 20060101
Hypoxanthine as a graft ischemia marker stimulates catalase activity in the renal vein during reperfusion in humans. Transplantation proceedings 20060101
A class of human exons with predicted distant branch points revealed by analysis of AG dinucleotide exclusion zones. Genome biology 20060101
Challenging the spliceosome machine. Genome biology 20060101
Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks. BMC genomics 20060101
New agents for the treatment of acute myeloid leukemia. Best practice & research. Clinical haematology 20060101
Suppression of inflammation by low-dose methotrexate is mediated by adenosine A2A receptor but not A3 receptor activation in thioglycollate-induced peritonitis. Arthritis research & therapy 20060101
[ADP-ribose and cADP-ribose--endogenous regulators of cellular ionic balance. Cardiotropic effects of ADP-ribose]. Uspekhi fiziologicheskikh nauk 20060101
Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms. BMC bioinformatics 20060101
Microbial identification by mass cataloging. BMC bioinformatics 20060101
Recognition and activation of ryanodine receptors by purines. Current medicinal chemistry 20060101
Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21. BMC medical genetics 20060101
Asymptomatic bacteriuria in sickle cell disease: a cross-sectional study. BMC infectious diseases 20060101
Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells. BMC developmental biology 20060101
DNA deformability changes of single base pair mutants within CDE binding sites in S. Cerevisiae centromere DNA correlate with measured chromosomal loss rates and CDE binding site symmetries. BMC molecular biology 20060101
Development of an unbiased statistical method for the analysis of unigenic evolution. BMC bioinformatics 20060101
Analysis of transitions at two-fold redundant sites in mammalian genomes. Transition redundant approach-to-equilibrium (TREx) distance metrics. BMC evolutionary biology 20060101
An application of statistics to comparative metagenomics. BMC bioinformatics 20060101
Amino acid size, charge, hydropathy indices and matrices for protein structure analysis. Theoretical biology & medical modelling 20060101
[The usefulness of adenosine deaminase determination in biological fluids for tuberculosis diagnosis]. Annales de biologie clinique 20060101
The chemopreventive properties of chlorogenic acid reveal a potential new role for the microsomal glucose-6-phosphate translocase in brain tumor progression. Cancer cell international 20060101
Uneven distribution of nucleoside transporters and intracellular enzymatic degradation prevent transport of intact [14C] adenosine across the sheep choroid plexus epithelium as a monolayer in primary culture. Cerebrospinal fluid research 20060101
Use of physiological constraints to identify quantitative design principles for gene expression in yeast adaptation to heat shock. BMC bioinformatics 20060101
Specific age-related signatures in Drosophila body parts transcriptome. BMC genomics 20060101
Whitefly (Bemisia tabaci) genome project: analysis of sequenced clones from egg, instar, and adult (viruliferous and non-viruliferous) cDNA libraries. BMC genomics 20060101
The complete plastid genome sequence of the parasitic green alga Helicosporidium sp. is highly reduced and structured. BMC biology 20060101
Partial HPRT deficiency (Kelley-Seegmiller syndrome). The Journal of the Association of Physicians of India 20060101
Molybdenum cofactor biosynthesis and molybdenum enzymes. Annual review of plant biology 20060101
Pyrimidine and purine biosynthesis and degradation in plants. Annual review of plant biology 20060101
High-throughput screening of cellulase F mutants from multiplexed plasmid sets using an automated plate assay on a functional proteomic robotic workcell. Proteome science 20060101
Determining the structural basis for specificity of ligands using crystallographic screening. Cell biochemistry and biophysics 20060101
Reactive oxygen species: role in the development of cancer and various chronic conditions. Journal of carcinogenesis 20060101
[Current views about the role of purin metabolism disorders in patients with arterial hypertension and losartan potentialities]. Kardiologiia 20060101
A nucleolar localizing Rev binding element inhibits HIV replication. AIDS research and therapy 20060101
Phylogeny based discovery of regulatory elements. BMC bioinformatics 20060101
The physiological regulation of uncoupling proteins. Biochimica et biophysica acta 20060101
A protein evolution model with independent sites that reproduces site-specific amino acid distributions from the Protein Data Bank. BMC evolutionary biology 20060101
Gene expression in cortex and hippocampus during acute pneumococcal meningitis. BMC biology 20060101
Locked nucleoside analogues expand the potential of DNAzymes to cleave structured RNA targets. BMC molecular biology 20060101
Pyrite-induced hydroxyl radical formation and its effect on nucleic acids. Geochemical transactions 20060101
Free radical theory of autoimmunity. Theoretical biology & medical modelling 20060101
Chemosensory properties of murine nasal and cutaneous trigeminal neurons identified by viral tracing. BMC neuroscience 20060101
The Yersinia pestis gcvB gene encodes two small regulatory RNA molecules. BMC microbiology 20060101
Transcriptome analysis of Deinagkistrodon acutus venomous gland focusing on cellular structure and functional aspects using expressed sequence tags. BMC genomics 20060101
Uncoupling proteins: a role in protection against reactive oxygen species--or not? Biochimica et biophysica acta 20060101
Singlet oxygen oxidation of isolated and cellular DNA: product formation and mechanistic insights. Photochemistry and photobiology 20060101
Recent advances in chronic lymphocytic leukemia. Cancer investigation 20060101
[Hairy cell leukemia: prognosis and treatment]. La Clinica terapeutica 20060101
A concise history of gout and hyperuricemia and their treatment. Arthritis research & therapy 20060101
Epidemiology, risk factors, and lifestyle modifications for gout. Arthritis research & therapy 20060101
Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics. Arthritis research & therapy 20060101
Stem-loop structures in prokaryotic genomes. BMC genomics 20060101
Topoisomerase II trapping agent teniposide induces apoptosis and G2/M or S phase arrest of oral squamous cell carcinoma. World journal of surgical oncology 20060101
Analysis of RNA splicing defects in PITX2 mutants supports a gene dosage model of Axenfeld-Rieger syndrome. BMC medical genetics 20060101
Selective inhibition of the human tie-1 promoter with triplex-forming oligonucleotides targeted to Ets binding sites. Molecular medicine (Cambridge, Mass.) 20060101
Structural property of DNA that migrates faster in gel electrophoresis, as deduced by CD spectroscopy. Nucleosides, nucleotides & nucleic acids 20060101
Recognition of oxidized thymine base on the single-stranded DNA by replication protein A. Nucleosides, nucleotides & nucleic acids 20060101
Apoptotic effect of ganciclovir on primary effusion lymphoma cells infected with Kaposi's sarcoma-associated herpesvirus. Nucleosides, nucleotides & nucleic acids 20060101
Synthesis and biological properties of new phosmidosine analogs having an N-acylsulfamate linkage. Nucleosides, nucleotides & nucleic acids 20060101
Adenylosuccinate lyase deficiency. Molecular genetics and metabolism 20060101
The purinome, a complex mix of drug and toxicity targets. Current topics in medicinal chemistry 20060101
Targeting cancer: the challenges and successes of structure-based drug design against the human purinome. Current topics in medicinal chemistry 20060101
Association of poly-purine/poly-pyrimidine sequences with meiotic recombination hot spots. BMC genomics 20060101
MANET: tracing evolution of protein architecture in metabolic networks. BMC bioinformatics 20060101
Design principles of molecular networks revealed by global comparisons and composite motifs. Genome biology 20060101
Water-elutability of nucleic acids from metal-chelate affinity adsorbents: enhancement by control of surface charge density. Journal of molecular recognition : JMR 20060101
Alkaline fluid circulation in ultramafic rocks and formation of nucleotide constituents: a hypothesis. Geochemical transactions 20060101
Analysis of Nanoarchaeum equitans genome and proteome composition: indications for hyperthermophilic and parasitic adaptation. BMC genomics 20060101
Transient change in GABA(A) receptor subunit mRNA expression in Lurcher cerebellar nuclei during Purkinje cell degeneration. BMC neuroscience 20060101
Identification of new participants in the rainbow trout (Oncorhynchus mykiss) oocyte maturation and ovulation processes using cDNA microarrays. Reproductive biology and endocrinology : RB&E 20060101
Recently published papers: dying Swans and other stories. Critical care (London, England) 20060101
Identification of transposon insertion mutants of Francisella tularensis tularensis strain Schu S4 deficient in intracellular replication in the hepatic cell line HepG2. BMC microbiology 20060101
Hairy cell leukemia: an elusive but treatable disease. The oncologist 20060101
Histone deacetylase enzymes as potential drug targets in cancer and parasitic diseases. Journal of biomedicine & biotechnology 20060101
Laminin-332 alters connexin profile, dye coupling and intercellular Ca2+ waves in ciliated tracheal epithelial cells. Respiratory research 20060101
Antiproliferative and proapoptotic activities of pyranoxanthenones, pyranothioxanthenones and their pyrazole-fused derivatives in HL-60 cells. Anticancer research 20060101
Genomic structure and expression of uncoupling protein 2 genes in rainbow trout (Oncorhynchus mykiss). BMC genomics 20060101
Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway. BMC genomics 20060101
Synthesis of 2'-amino-LNA purine nucleosides. Nucleosides, nucleotides & nucleic acids 20060101
A preventive approach to oral self-mutilation in Lesch-Nyhan syndrome: a case report. Pediatric dentistry 20060101
[The effect of modification of tRNA nucleotide-37 on the tRNA interaction with the P- and A-site of the 70S ribosome Escherichia coli]. Molekuliarnaia biologiia 20060101
In vitro growth inhibition of bloodstream forms of Trypanosoma brucei and Trypanosoma congolense by iron chelators. Kinetoplastid biology and disease 20060101
Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae. BMC bioinformatics 20060101
Transcriptional and structural impact of TATA-initiation site spacing in mammalian core promoters. Genome biology 20060101
Comparative kinetic analysis of AzgA and Fcy21p, prototypes of the two major fungal hypoxanthine-adenine-guanine transporter families. Molecular membrane biology 20060101
The first transmembrane segment (TMS1) of UapA contains determinants necessary for expression in the plasma membrane and purine transport. Molecular membrane biology 20060101
Fast index based algorithms and software for matching position specific scoring matrices. BMC bioinformatics 20060101
[Genetically determined gout: characteristics of the course]. TSitologiia i genetika 20060101
Virulence properties of cariogenic bacteria. BMC oral health 20060101
Cri du Chat syndrome. Orphanet journal of rare diseases 20060101
Serum adenosine deaminase activity in monitoring disease activity and response to therapy in severe psoriasis. Acta medica (Hradec Kralove) 20060101
Renal lithiasis and nutrition. Nutrition journal 20060101
Cytomegalovirus-induced embryopathology: mouse submandibular salivary gland epithelial-mesenchymal ontogeny as a model. BMC developmental biology 20060101
Amdoxovir versus placebo with enfuvirtide plus optimized background therapy for HIV-1-infected subjects failing current therapy (AACTG A5118). Antiviral therapy 20060101
Uncoupling proteins, dietary fat and the metabolic syndrome. Nutrition & metabolism 20060101
When transcriptome meets metabolome: fast cellular responses of yeast to sudden relief of glucose limitation. Molecular systems biology 20060101
The complete mitochondrial genome of a basal teleost, the Asian arowana (Scleropages formosus, Osteoglossidae). BMC genomics 20060101
LIGSITEcsc: predicting ligand binding sites using the Connolly surface and degree of conservation. BMC structural biology 20060101
Comparative assessment of performance and genome dependence among phylogenetic profiling methods. BMC bioinformatics 20060101
Multiple opportunistic infections after high-dose steroid therapy for giant cell arteritis in a patient previously treated with a purine analog. Scandinavian journal of infectious diseases 20060101
Immunosuppressive drugs in HIV disease. Current topics in medicinal chemistry 20060101
Tumor suppressor gene methylation in follicular lymphoma: a comprehensive review. Molecular cancer 20060101
A study of the purine derivative AIT-082 in G93A SOD1 transgenic mice. International journal of immunopathology and pharmacology 20060101
Evaluation of NTHL1, NEIL1, NEIL2, MPG, TDG, UNG and SMUG1 genes in familial colorectal cancer predisposition. BMC cancer 20060101
The TGF-beta1/upstream stimulatory factor-regulated PAI-1 gene: potential involvement and a therapeutic target in Alzheimer's disease. Journal of biomedicine & biotechnology 20060101
Oxidative damage to RNA in neurodegenerative diseases. Journal of biomedicine & biotechnology 20060101
Dicer-derived microRNAs are utilized by the fragile X mental retardation protein for assembly on target RNAs. Journal of biomedicine & biotechnology 20060101
An enhanced RNA alignment benchmark for sequence alignment programs. Algorithms for molecular biology : AMB 20060101
Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design. BMC structural biology 20060101
Purine and pyrimidine metabolism: a firm basis for a transformed society. Nucleosides, nucleotides & nucleic acids 20060101
Familial juvenile hyperuricaemic nephropathy is not such a rare genetic metabolic purine disease in Britain. Nucleosides, nucleotides & nucleic acids 20060101
Efficacy and safety of allopurinol in patients with the Lesch-Nyhan syndrome and partial hypoxanthine- phosphoribosyltransferase deficiency: a follow-up study of 18 Spanish patients. Nucleosides, nucleotides & nucleic acids 20060101
Effect of beer ingestion on the plasma concentrations and urinary excretion of purine bases: one-month study. Nucleosides, nucleotides & nucleic acids 20060101
Differences in activities of the enzymes of nucleotide metabolism and its implications for cardiac xenotransplantation. Nucleosides, nucleotides & nucleic acids 20060101
Synthesis and mass spectrometric fragmentation characteristics of imidazole ribosides-analogs of intermediates of purine de novo synthetic pathway. Nucleosides, nucleotides & nucleic acids 20060101
5 '-Amino-4-imidazolecarboxamide riboside induces apoptosis in human neuroblastoma cells via the mitochondrial pathway. Nucleosides, nucleotides & nucleic acids 20060101
Purine metabolism in B-cell lymphocytic leukemia: a microarray approach. Nucleosides, nucleotides & nucleic acids 20060101
Purine metabolism and clinical status of patients with rheumatoid arthritis treated with dipyridamole. Nucleosides, nucleotides & nucleic acids 20060101
Purine catabolism in advanced carotid artery plaque. Nucleosides, nucleotides & nucleic acids 20060101
Analysis of excretion fraction of uric acid. Nucleosides, nucleotides & nucleic acids 20060101
An unusual cause of renal amyloidosis secondary to gout: the first description of familial occurrence. Nucleosides, nucleotides & nucleic acids 20060101
Microwave-assisted ring closure reactions: synthesis of 8-substituted xanthine derivatives and related pyrimido- and diazepinopurinediones. Beilstein journal of organic chemistry 20060101
Action of nucleosides and nucleotides at 7 transmembrane-spanning receptors. Nucleosides, nucleotides & nucleic acids 20060101
Bifidobacterium infantis strains with and without a combination of oligofructose and inulin (OFI) attenuate inflammation in DSS-induced colitis in rats. BMC gastroenterology 20060101
An improved and highly sensitive microfluorimetric method for assessing susceptibility of Plasmodium falciparum to antimalarial drugs in vitro. Malaria journal 20060101
Cytokinins inhibit epiphyllous plantlet development on leaves of Bryophyllum (Kalanchoë) marnierianum. Journal of experimental botany 20060101
BoCaTFBS: a boosted cascade learner to refine the binding sites suggested by ChIP-chip experiments. Genome biology 20060101
Pathway-specific differences between tumor cell lines and normal and tumor tissue cells. Molecular cancer 20060101
Adenosine deaminase from camel tick Hyalomma dromedarii: purification and characterization. Experimental & applied acarology 20060101
Critical roles of glutamine as nitrogen donors in purine and pyrimidine nucleotide synthesis: asparaginase treatment in childhood acute lymphoblastic leukemia. In vivo (Athens, Greece) 20060101
Huntingtin gene evolution in Chordata and its peculiar features in the ascidian Ciona genus. BMC genomics 20060101
The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20060101
Cyclin-dependent kinase (CDK) inhibitor olomoucine enhances gamma-irradiation-induced apoptosis and cell cycle arrest in Raji cells. Anticancer research 20060101
Metabolic network driven analysis of genome-wide transcription data from Aspergillus nidulans. Genome biology 20060101
Integration and mining of malaria molecular, functional and pharmacological data: how far are we from a chemogenomic knowledge space? Malaria journal 20060101
Gene expression profiling following constitutive activation of MEK1 and transformation of rat intestinal epithelial cells. Molecular cancer 20060101
Gene expression profiles distinguish the carcinogenic effects of aristolochic acid in target (kidney) and non-target (liver) tissues in rats. BMC bioinformatics 20060101
Exploring glycopeptide-resistance in Staphylococcus aureus: a combined proteomics and transcriptomics approach for the identification of resistance-related markers. BMC genomics 20060101
Immune hemolytic anemia--selected topics. Hematology. American Society of Hematology. Education Program 20060101
CNS progenitor cells and oligodendrocytes are targets of chemotherapeutic agents in vitro and in vivo. Journal of biology 20060101
Targeting of toxic compounds to the trypanosome's interior. Advances in parasitology 20060101
Mechanisms of genotoxin-induced transcription and hypermutation in p53. Cancer cell international 20060101
Ethanol sensitivity: a central role for CREB transcription regulation in the cerebellum. BMC genomics 20060101
In silico experimentation with a model of hepatic mitochondrial folate metabolism. Theoretical biology & medical modelling 20060101
A strategy for selective N-acylation of purine and pyrimidine bases of deoxy and ribo nucleosides. Nucleic acids symposium series (2004) 20060101
Synthesis of 2',4'-BNACOC bearing a purine nucleobase. Nucleic acids symposium series (2004) 20060101
Structural property and enzymatic response of oxanine in DNA strands. Nucleic acids symposium series (2004) 20060101
Anti-SARS-CoV activity of nucleoside analogs having 6-chloropurine as a nucleobase. Nucleic acids symposium series (2004) 20060101
Development of novel PRODAN-labeled nucleosides as base-discriminating fluorescent probes. Nucleic acids symposium series (2004) 20060101
Effects of the modified aromatic ring of WNA on stability of triplex DNA. Nucleic acids symposium series (2004) 20060101
Purine nucleoside analogs as immunosuppressive and antineoplastic agents: mechanism of action and clinical activity. Current medicinal chemistry 20060101
Ligands for A2B adenosine receptor subtype. Current medicinal chemistry 20060101
A computational analysis of the three isoforms of glutamate dehydrogenase reveals structural features of the isoform EC 1.4.1.4 supporting a key role in ammonium assimilation by plants. Biology direct 20060101
Transcription profile of a human breast cancer cell line expressing MMTV-like sequences. Infectious agents and cancer 20060101
Investigation of the molecular profile of basal cell carcinoma using whole genome microarrays. Molecular cancer 20060101
Mariner mutagenesis of Brucella melitensis reveals genes with previously uncharacterized roles in virulence and survival. BMC microbiology 20060101
Role of pyrite in formation of hydroxyl radicals in coal: possible implications for human health. Particle and fibre toxicology 20060101
Effect of long-term exposure of SH-SY5Y cells to morphine: a whole cell proteomic analysis. Proteome science 20060101
Comprehensive analysis of alternative splicing in rice and comparative analyses with Arabidopsis. BMC genomics 20060101
Analysis of rice glycosyl hydrolase family 1 and expression of Os4bglu12 beta-glucosidase. BMC plant biology 20060101
Structures, mechanism, regulation and evolution of class III nucleotidyl cyclases. Reviews of physiology, biochemistry and pharmacology 20060101
[Guanosine and inosine as natural geneprotectors for mice blood cells exposed to X-rays]. Radiatsionnaia biologiia, radioecologiia 20060101
Structural studies of the purine and SAM binding riboswitches. Cold Spring Harbor symposia on quantitative biology 20060101
New Dihydro OO'Bis(Salicylidene) 2,2' Aminobenzothiazolyl Borate Complexes: Kinetic and Voltammetric Studies of Dimethyltin Copper Complex with Guanine, Adenine, and Calf Thymus DNA. Bioinorganic chemistry and applications 20060101
Changes in plasma concentrations of hypoxanthine and xanthine in renal vein as an index of delayed kidney allograft function. Urology journal 20060101
Modeling of phosphomethyl pyrimidine kinase from Leptospira interrogans serovar lai strain 56601. Bioinformation 20060101
Functional annotation of hypothetical proteins - A review. Bioinformation 20060101
Insight into gene fusion from molecular dynamics simulation of fused and un-fused IGPS (Imidazole Glycerol Phosphate Synthetase). Bioinformation 20060101
Older and new formulations of cladribine. Pharmacology and clinical efficacy in hematological malignancies. Recent patents on anti-cancer drug discovery 20060101
Recent clinical trials of cladribine in hematological malignancies and autoimmune disorders. Reviews on recent clinical trials 20060101
A nuclear ribosomal DNA phylogeny of acer inferred with maximum likelihood, splits graphs, and motif analysis of 606 sequences. Evolutionary bioinformatics online 20060101
Structure of homeodomain-leucine zipper/DNA complexes studied using hydroxyl radical cleavage of DNA and methylation interference. Biochemistry 20051227
Facile preparation of the oxetane-nucleosides. Organic & biomolecular chemistry 20051221
Prevention of MKK6-dependent activation by binding to p38alpha MAP kinase. Biochemistry 20051220
Differential interactions of G-proteins and adenylyl cyclase with nucleoside 5'-triphosphates, nucleoside 5'-[gamma-thio]triphosphates and nucleoside 5'-[beta,gamma-imido]triphosphates. Biochemical pharmacology 20051219
6-Benzylthioinosine analogues: promising anti-toxoplasmic agents as inhibitors of the mammalian nucleoside transporter ENT1 (es). Biochemical pharmacology 20051219
Inverting the charges of natural nucleobase quartets: a planar platinum-purine quartet with pronounced sulfate affinity. Angewandte Chemie (International ed. in English) 20051216
A proof-of-principle pharmacokinetic, pharmacodynamic, and clinical study with purine nucleoside phosphorylase inhibitor immucillin-H (BCX-1777, forodesine). Blood 20051215
Differential effect of insulin and elevated glucose level on adenosine handling in rat T lymphocytes. Journal of cellular biochemistry 20051215
Design and synthesis of N-benzylpiperidine-purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase. Bioorganic & medicinal chemistry 20051215
Tacrolimus-induced alopecia in female kidney-pancreas transplant recipients. Transplantation 20051215
The human equilibrative nucleoside transporter 1 mediates in vitro cytarabine sensitivity in childhood acute myeloid leukaemia. British journal of cancer 20051212
Red wine polyphenols influence carcinogenesis, intestinal microflora, oxidative damage and gene expression profiles of colonic mucosa in F344 rats. Mutation research 20051211
The leukocyte count predicts the efficacy of treatment with azathioprine in inflammatory bowel disease. European journal of medical research 20051207
Experimental therapy of allogeneic solid tumors induced in athymic mice with suicide gene-transducing replication-competent foamy virus vectors. Cancer gene therapy 20051201
Selective anti-tubercular purines: synthesis and chemotherapeutic properties of 6-aryl- and 6-heteroaryl-9-benzylpurines. Bioorganic & medicinal chemistry 20051201
Effects of aging on the relation of adenyl purine release with plasma membrane fluidity of arterial endothelial cells. Prostaglandins, leukotrienes, and essential fatty acids 20051201
Long remissions in hairy cell leukemia with purine analogs: a report of 219 patients with a median follow-up of 12.5 years. Cancer 20051201
The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K. Nature biotechnology 20051201
Acute pancreatitis in patients with Crohn's disease: clinical features and outcomes. Inflammatory bowel diseases 20051201
Changes in the natural history of progressive multifocal leukoencephalopathy in HIV-negative lymphoproliferative disorders: impact of novel therapies. American journal of hematology 20051201
An evaluation of pemetrexed in second-line treatment of non-small cell lung cancer. Expert opinion on pharmacotherapy 20051201
Phase I study of low-dose interleukin-2, fludarabine, and cyclophosphamide for previously untreated indolent lymphoma and chronic lymphocytic leukemia. Clinical cancer research : an official journal of the American Association for Cancer Research 20051201
The Systemic Theory of Living Systems. Part IV: Systemic Medicine--The Praxis. Evidence-based complementary and alternative medicine : eCAM 20051201
Substrate specificity of vaccinia virus thymidylate kinase. The FEBS journal 20051201
Homozygous deletions of methylthioadenosine phosphorylase in human biliary tract cancers. Molecular cancer therapeutics 20051201
Toxoplasma gondii: localization of purine nucleoside phosphorylase activity in vitro and in vivo by electron microscopy. Medical molecular morphology 20051201
Inosine infusion prevents mortality in endotoxic shock. The Journal of trauma 20051201
Strand displacement of double-stranded DNA by triplex-forming antiparallel purine-hairpins. Oligonucleotides 20051201
[Genetic testing and gene-based testing for hyperuricemia and gout]. Nihon rinsho. Japanese journal of clinical medicine 20051201
Harnessing natural diversity to probe metabolic pathways. PLoS genetics 20051201
Bolus injection of adenosine before cardioplegic induction improves postischemic global function in coronary artery bypass grafting. Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20051201
[Epidemiology of infections in neutropenic patients]. Enfermedades infecciosas y microbiologia clinica 20051201
Microbiologic consequences of new approaches to managing hematologic malignancies. Reviews in clinical and experimental hematology 20051201
Editorial. Purinergic signalling 20051201
First joint Italian-German purine club meeting 'Progress in Purinergic Receptor Pharmacology and Function'. Purinergic signalling 20051201
ATP release via anion channels. Purinergic signalling 20051201
Cell cycle regulation of astrocytes by extracellular nucleotides and fibroblast growth factor-2. Purinergic signalling 20051201
The priming effect of extracellular UTP on human neutrophils: Role of calcium released from thapsigargin-sensitive intracellular stores. Purinergic signalling 20051201
Herpes simplex virus 1 primase employs watson-crick hydrogen bonding to identify cognate nucleoside triphosphates. Biochemistry 20051129
Crystal structure of a purine/pyrimidine phosphoribosyltransferase-related protein from Thermus thermophilus HB8. Proteins 20051115
Polymer supported carbodiimide strategy for the synthesis of N-acylated derivatives of deoxy- and ribo purinenucleosides using active esters. Bioorganic & medicinal chemistry letters 20051115
A trans acting ribozyme that phosphorylates exogenous RNA. Biochemistry 20051115
Size-expanded DNA bases: an ab initio study of their structural and electronic properties. The journal of physical chemistry. B 20051110
Binding of 5'-GMP to the GluR2 AMPA receptor: insight from targeted molecular dynamics simulations. Biochemistry 20051108
Structural insights into enzyme regulation for inositol 1,4,5-trisphosphate 3-kinase B. Biochemistry 20051108
2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine and analogues as A2A adenosine receptor antagonists. Design, synthesis, and pharmacological characterization. Journal of medicinal chemistry 20051103
A Golgi study of neuronal architecture in a genetic mouse model for Lesch-Nyhan disease. Neurobiology of disease 20051101
Role of 5'-nucleotidase in thiopurine metabolism: enzyme kinetic profile and association with thio-GMP levels in patients with acute lymphoblastic leukemia during 6-mercaptopurine treatment. Clinica chimica acta; international journal of clinical chemistry 20051101
Purine and pyrimidine transport in pathogenic protozoa: from biology to therapy. FEMS microbiology reviews 20051101
Effects of azathioprine and its metabolites on repair mechanisms of the intestinal epithelium in vitro. Regulatory peptides 20051101
In vivo co-ordinated interactions between inhibitory systems to control glutamate-mediated hippocampal excitability. Journal of neurochemistry 20051101
Synthesis, spectral study and cytotoxicity of platinum(II) complexes with 2,9-disubstituted-6-benzylaminopurines. Journal of inorganic biochemistry 20051101
Mutational analysis of the Bacillus subtilis purA operator site. Current microbiology 20051101
Like cops on the beat: the active role of resting microglia. Trends in neurosciences 20051101
Liquid chromatography-tandem mass spectrometry analysis of erythrocyte thiopurine nucleotides and effect of thiopurine methyltransferase gene variants on these metabolites in patients receiving azathioprine/6-mercaptopurine therapy. Clinical chemistry 20051101
3-Nitrobenzanthrone, a potential human cancer hazard in diesel exhaust and urban air pollution: a review of the evidence. Mutagenesis 20051101
New developments in the diagnosis, prognosis and treatment of chronic lymphocytic leukemia. Current opinion in oncology 20051101
Effect of abomasal pectin infusion on digestion and nitrogen balance in lactating dairy cows. Journal of dairy science 20051101
Comparison of four markers for quantifying microbial protein flow from the rumen of lactating dairy cows. Journal of dairy science 20051101
Novel multisubstrate inhibitors of mammalian purine nucleoside phosphorylase. Acta crystallographica. Section D, Biological crystallography 20051101
Identification of three urease accessory proteins that are required for urease activation in Arabidopsis. Plant physiology 20051101
Identification of Arabidopsis salt and osmotic stress responsive proteins using two-dimensional difference gel electrophoresis and mass spectrometry. Proteomics 20051101
Personal exposure to ultrafine particles and oxidative DNA damage. Environmental health perspectives 20051101
Reduced thymic output, increased spontaneous apoptosis and oligoclonal B cells in polyethylene glycol-adenosine deaminase-treated patients. European journal of immunology 20051101
Polymorphisms in the reduced folate carrier, thymidylate synthase, or methionine synthase and risk of colon cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20051101
Understanding treatments for gout. The American journal of managed care 20051101
Determination of 13C CSA tensors: extension of the model-independent approach to an RNA kissing complex undergoing anisotropic rotational diffusion in solution. Journal of biomolecular NMR 20051101
[High intestinal transport activity for nucleosides in cattle: a synopsis]. DTW. Deutsche tierarztliche Wochenschrift 20051101
[Effects of exogenerous nucleotides on the apoptosis of intestinal epithelial cells IEC-6]. Wei sheng yan jiu = Journal of hygiene research 20051101
Pyrazolo[4,3-e][1,2,4]triazines: purine analogues with electronic absorption in the visible region. Molecules (Basel, Switzerland) 20051031
Purine activity of RNase T1RV is further improved by substitution of Trp59 by tyrosine. Biochemical and biophysical research communications 20051028
Structures for the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni causal agent of schistosomiasis. Journal of molecular biology 20051028
Design and evaluation of dihydroxytetrahydro-1H-pyrrolo[2,1-c]- [1,4]benzothiazines as conformationally restricted transition-state inhibitors of beta-ribosidases. The Journal of organic chemistry 20051028
Simple ethers as models of sugar molecules in calculations of vertical excitation energies of DNA and RNA nucleosides. The journal of physical chemistry. A 20051027
Correlation between strand asymmetry and phylogeny in mitochondrial DNA. Journal of theoretical biology 20051021
Lymphocyte Hprt mutant frequency and sperm toxicity in C57BL/6 mice treated chronically with Azathioprine. Mutation research 20051015
Hypermutation at A-T base pairs: the A nucleotide replacement spectrum is affected by adjacent nucleotides and there is no reverse complementarity of sequences flanking mutated A and T nucleotides. Journal of immunology (Baltimore, Md. : 1950) 20051015
Short-term safety and pharmacodynamics of amdoxovir in HIV-infected patients. AIDS (London, England) 20051014
DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone after intratracheal instillation in rats. International journal of cancer 20051010
Pathogenesis of gout. Annals of internal medicine 20051004
[Uric acid as a marker of pathophysiological mechanisms in patients with cardiovascular disease]. Ugeskrift for laeger 20051003
Nucleoside transporter expression and function in cultured mouse astrocytes. Glia 20051001
l-Arginine attenuates cardiovascular impairment in DOCA-salt hypertensive rats. American journal of physiology. Heart and circulatory physiology 20051001
Differences in the neurotoxicity profile induced by ATP and ATPgammaS in cultured cerebellar granule neurons. Neurochemistry international 20051001
Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy. Clinical chemistry 20051001
Comparison between reduced intensity and conventional myeloablative allogeneic stem-cell transplantation in patients with hematologic malignancies aged between 50 and 59 years. Bone marrow transplantation 20051001
Adenosine receptor signaling in the brain immune system. Trends in pharmacological sciences 20051001
Old and new insights into the mechanisms of action of two nucleoside analogs active in lymphoid malignancies: fludarabine and cladribine (review). International journal of oncology 20051001
Empiric therapy of autoimmune hepatitis with mycophenolate mofetil: comparison with conventional treatment for refractory disease. Journal of clinical gastroenterology 20051001
The influence of allopurinol on urinary purine loss after repeated sprint exercise in man. Metabolism: clinical and experimental 20051001
Kinetics and crystal structure of human purine nucleoside phosphorylase in complex with 7-methyl-6-thio-guanosine. Archives of biochemistry and biophysics 20051001
The identification of 5'-fluoro-5-deoxyinosine as a shunt product in cell free extracts of Streptomyces cattleya. Bioorganic chemistry 20051001
Nucleoside 5'-triphosphates: self-association, acid-base, and metal ion-binding properties in solution. Chemical Society reviews 20051001
High activity and incomplete cross resistance of nucleoside analogues cladribine and fludarabine versus Ara-C on leukemic cells from patients with AML. Therapeutic drug monitoring 20051001
Dependence of nucleotide physical properties on their placement in codons and determinative degree. Journal of Zhejiang University. Science. B 20051001
Structure and energetics of clustered damage sites. Radiation research 20051001
DNA-bound Bas1 recruits Pho2 to activate ADE genes in Saccharomyces cerevisiae. Eukaryotic cell 20051001
Protein molecular function prediction by Bayesian phylogenomics. PLoS computational biology 20051001
Successful treatment of refractory thrombocytopenia with mycophenolate mofetil in a patient with systemic lupus erythematosus. Journal of Korean medical science 20051001
A3 adenosine receptors modulate hypoxia-inducible factor-1alpha expression in human A375 melanoma cells. Neoplasia (New York, N.Y.) 20051001
A single-cell analysis of myogenic dedifferentiation induced by small molecules. Chemistry & biology 20051001
Effects of long-term beer ingestion on plasma concentrations and urinary excretion of purine bases. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20051001
Allopurinol or oxypurinol in heart failure therapy - a promising new development or end of story? Cardiovascular drugs and therapy 20051001
Mycophenolate mofetil in organ transplantation: focus on metabolism, safety and tolerability. Expert opinion on drug metabolism & toxicology 20051001
Synthesis of enantiomerically pure (purin-6-yl)phenylalanines and their nucleosides, a novel type of purine-amino acid conjugates. The Journal of organic chemistry 20050930
Structural snapshots of MTA/AdoHcy nucleosidase along the reaction coordinate provide insights into enzyme and nucleoside flexibility during catalysis. Journal of molecular biology 20050923
Phenyl radicals react with dinucleoside phosphates by addition to purine bases and H-atom abstraction from a sugar moiety. Journal of the American Chemical Society 20050921
8-Azapurines as new inhibitors of cyclin-dependent kinases. Bioorganic & medicinal chemistry 20050915
Endogenous DNA damage clusters in human skin, 3-D model, and cultured skin cells. Free radical biology & medicine 20050915
Identification of nicotinamide N-methyltransferase as a novel serum tumor marker for colorectal cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 20050915
Molecular recognition via triplex formation of mixed purine/pyrimidine DNA sequences using oligoTRIPs. Journal of the American Chemical Society 20050914
Immediate up-regulation of the calcium-binding protein S100P and its involvement in the cytokinin-induced differentiation of human myeloid leukemia cells. Biochimica et biophysica acta 20050910
Current treatment approaches for mantle-cell lymphoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050910
Cytostatic 6-arylpurine nucleosides. 6. SAR in anti-HCV and cytostatic activity of extended series of 6-hetarylpurine ribonucleosides. Journal of medicinal chemistry 20050908
Uncoupling protein 3 protects aconitase against inactivation in isolated skeletal muscle mitochondria. Biochimica et biophysica acta 20050905
A novel method for the synthesis of imidazo[5,1-f][1,2,4]triazin-4(3H)-ones. The Journal of organic chemistry 20050902
Glutamine inhibits cytokine-induced apoptosis in human colonic epithelial cells via the pyrimidine pathway. American journal of physiology. Gastrointestinal and liver physiology 20050901
Infections associated with purine analogs and monoclonal antibodies. Blood reviews 20050901
Advances in understanding adenosine as a plurisystem modulator in sepsis and the systemic inflammatory response syndrome (SIRS). Frontiers in bioscience : a journal and virtual library 20050901
The yicM (nepI) gene of Escherichia coli encodes a major facilitator superfamily protein involved in efflux of purine ribonucleosides. FEMS microbiology letters 20050901
Specificity of recognition of mRNA 5' cap by human nuclear cap-binding complex. RNA (New York, N.Y.) 20050901
Mechanical loading stimulates ecto-ATPase activity in human tendon cells. Journal of cellular biochemistry 20050901
Advances in the treatment of chronic lymphocytic leukemia. Current oncology reports 20050901
Inhibition of endothelial activation: a new way to treat cerebral malaria? PLoS medicine 20050901
The genomics of disulfide bonding and protein stabilization in thermophiles. PLoS biology 20050901
Regioselective syntheses of 7-nitro-7-deazapurine nucleosides and nucleotides for efficient PCR incorporation. Organic letters 20050901
An unusual occurrence on attempted purine C-8 electrophilic fluorination of 5'-noraristeromycin. Organic letters 20050901
Adenosine deaminase and 5'-nucleotidase activities in saliva from patients with oral and laryngeal cancer. Oral diseases 20050901
Purine metabolites in gout and asymptomatic hyperuricemia: analysis by HPLC-electrospray tandem mass spectrometry. Clinical chemistry 20050901
Myocardial and coronary sinus purines as indicators of pig heart energy metabolism during reperfusion after extracorporeal circulation. Acta physiologica Scandinavica 20050901
Structures of Plasmodium falciparum purine nucleoside phosphorylase complexed with sulfate and its natural substrate inosine. Acta crystallographica. Section D, Biological crystallography 20050901
The systemic theory of living systems and relevance to CAM: the theory (Part III). Evidence-based complementary and alternative medicine : eCAM 20050901
The pharmacological potential of mushrooms. Evidence-based complementary and alternative medicine : eCAM 20050901
Polymerization past the N2-isopropylguanine and the N6-isopropyladenine DNA lesions with the translesion synthesis DNA polymerases eta and iota and the replicative DNA polymerase alpha. Chemical research in toxicology 20050901
The structure of DNA dictates purine atom site selectivity in alkylation by primary diazonium ions. Chemical research in toxicology 20050901
Regional differences in extracellular purine degradation in the prostatic and epididymal portions of the rat vas deferens. Clinical and experimental pharmacology & physiology 20050901
Purine nucleoside analogues for the treatment of hematological malignancies: pharmacology and clinical applications. Current cancer drug targets 20050901
REC, Drosophila MCM8, drives formation of meiotic crossovers. PLoS genetics 20050901
Pentostatin/cyclophosphamide with or without rituximab: an effective regimen for patients with Waldenstrom's macroglobulinemia/lymphoplasmacytic lymphoma. Clinical lymphoma & myeloma 20050901
Signaling of the Human P2Y(1) Receptor Measured by a Yeast Growth Assay with Comparisons to Assays of Phospholipase C and Calcium Mobilization in 1321N1 Human Astrocytoma Cells. Purinergic signalling 20050901
P2X(7) receptor: Death or life? Purinergic signalling 20050901
Dynamic purine signaling and metabolism during neutrophil-endothelial interactions. Purinergic signalling 20050901
Cloning and characterization of the ecto-nucleotidase NTPDase3 from rat brain: Predicted secondary structure and relation to other members of the E-NTPDase family and actin. Purinergic signalling 20050901
Tri-nucleotide receptors play a critical role in epithelial cell wound repair. Purinergic signalling 20050901
Syntheses of RNAs with up to 100 nucleotides containing site-specific 2'-methylseleno labels for use in X-ray crystallography. Journal of the American Chemical Society 20050831
Procatalytic ligand strain. Ionization and perturbation of 8-nitroxanthine at the urate oxidase active site. Biochemistry 20050830
Energetic mapping of transition state analogue interactions with human and Plasmodium falciparum purine nucleoside phosphorylases. The Journal of biological chemistry 20050826
Design and synthesis of a series of melamine-based nitroheterocycles with activity against Trypanosomatid parasites. Journal of medicinal chemistry 20050825
Three-state conical intersections in nucleic acid bases. The journal of physical chemistry. A 20050825
Mutational analysis of a nucleosidase involved in quorum-sensing autoinducer-2 biosynthesis. Biochemistry 20050823
The first synthesis and cytostatic activity of novel 6-(fluoromethyl)purine bases and nucleosides. Organic & biomolecular chemistry 20050821
Total synthesis of N-malayamycin A and related bicyclic purine and pyrimidine nucleosides. The Journal of organic chemistry 20050819
Conformational change in the catalytic site of the ribonuclease YoeB toxin by YefM antitoxin. Molecular cell 20050819
Substrate discrimination by the human GTP fucose pyrophosphorylase. Biochemistry 20050816
Substituted purine analogues define a novel structural class of catalytic topoisomerase II inhibitors. Cancer research 20050815
Plasma and cerebrospinal fluid pharmacokinetics of clofarabine in nonhuman primates. Clinical cancer research : an official journal of the American Association for Cancer Research 20050815
The crystal structure of free human hypoxanthine-guanine phosphoribosyltransferase reveals extensive conformational plasticity throughout the catalytic cycle. Journal of molecular biology 20050805
Stabilization of purine motif DNA triplex by a tetrapeptide from the binding domain of HMGBI protein. Biochimie 20050801
Methylated purines in urinary stones. Clinical chemistry 20050801
Nucleotide metabolism and its control in lactic acid bacteria. FEMS microbiology reviews 20050801
A solid-phase approach to novel purine and nucleoside analogs. Bioorganic & medicinal chemistry 20050801
Tetrabutylammonium fluoride-assisted rapid N9-alkylation on purine ring: application to combinatorial reactions in microtiter plates for the discovery of potent sulfotransferase inhibitors in situ. Bioorganic & medicinal chemistry 20050801
Interaction centres of pyrimidine nucleotides: cytidine-5'-diphosphate (CDP) and cytidine-5'-triphosphate (CTP) in their reactions with tetramines and Cu(II) ions. Journal of inorganic biochemistry 20050801
Therapy-related acute myeloid leukemia after single-agent treatment with fludarabine for chronic lymphocytic leukemia. American journal of hematology 20050801
Emerging drugs for adult acute lymphoblastic leukaemia. Expert opinion on emerging drugs 20050801
A global survey of gene regulation during cold acclimation in Arabidopsis thaliana. PLoS genetics 20050801
6-(N-benzoylamino)purine as a novel and potent inhibitor of xanthine oxidase: inhibition mechanism and molecular modeling studies. Journal of enzyme inhibition and medicinal chemistry 20050801
Residue specific ribose and nucleobase dynamics of the cUUCGg RNA tetraloop motif by MNMR 13C relaxation. Journal of biomolecular NMR 20050801
Selective DNAzyme-mediated cleavage of AChR mutant transcripts by targeting the mutation site or through mismatches in the binding arm. Journal of RNAi and gene silencing : an international journal of RNA and gene targeting research 20050801
Inosine improves islet xenograft survival in immunocompetent diabetic mice. European journal of medical research 20050729
Increased expression of mRNA specific for thymidine kinase, deoxycytidine kinase or thymidine phosphorylase in human papillary thyroid carcinoma. Cancer letters 20050728
Antitumor activity of C-methyl-beta-D-ribofuranosyladenine nucleoside ribonucleotide reductase inhibitors. Journal of medicinal chemistry 20050728
Effects of hydrogen bonding on the acidity of adenine, guanine, and their 8-oxo derivatives. The journal of physical chemistry. A 20050721
Immunosuppression and infectious complications in patients with stage IV indolent lymphoma treated with a fludarabine, mitoxantrone, and dexamethasone regimen. Cancer 20050715
The nucleobase-ascorbate transporter (NAT) signature motif in UapA defines the function of the purine translocation pathway. Journal of molecular biology 20050715
Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase. Journal of medicinal chemistry 20050714
The broadly selective human Na+/nucleoside cotransporter (hCNT3) exhibits novel cation-coupled nucleoside transport characteristics. The Journal of biological chemistry 20050708
Chemical and biological evidence for base propenals as the major source of the endogenous M1dG adduct in cellular DNA. The Journal of biological chemistry 20050708
Stereoselective synthesis of beta-anomeric 4'-thiaspirocyclic ribonucleosides carrying the full complement of RNA-level hydroxyl substitution. The Journal of organic chemistry 20050708
Treatment of hairy cell leukemia with 2-chlorodeoxyadenosine (2-CdA): long-term follow-up of the Northwestern University experience. Blood 20050701
Structural elements in IGP synthase exclude water to optimize ammonia transfer. Biophysical journal 20050701
In vitro activity of cyclin-dependent kinase inhibitor CYC202 (Seliciclib, R-roscovitine) in mantle cell lymphomas. Annals of oncology : official journal of the European Society for Medical Oncology 20050701
Docking simulation with a purine nucleoside specific homology model of deoxycytidine kinase, a target enzyme for anticancer and antiviral therapy. Bioorganic & medicinal chemistry 20050701
A role for adenosine deaminase in Drosophila larval development. PLoS biology 20050701
AICAR suppresses IL-2 expression through inhibition of GSK-3 phosphorylation and NF-AT activation in Jurkat T cells. Biochemical and biophysical research communications 20050701
DNA repair is responsible for the presence of oxidatively damaged DNA lesions in urine. Mutation research 20050701
Contribution of the Saccharomyces cerevisiae transcriptional regulator Leu3p to physiology and gene expression in nitrogen- and carbon-limited chemostat cultures. FEMS yeast research 20050701
Birth of a metabolic gene cluster in yeast by adaptive gene relocation. Nature genetics 20050701
Structure of human PNP complexed with ligands. Acta crystallographica. Section D, Biological crystallography 20050701
[MTH1, an oxidized purine nucleoside triphosphatase suppresses mitochondrial dysfunction and cell death caused by oxidative stress]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20050701
Inhibition of urokinase receptor gene expression and cell invasion by anti-uPAR DNAzymes in osteosarcoma cells. The FEBS journal 20050701
Guanine-specific oxidation of double-stranded DNA by Cr(VI) and ascorbic acid forms spiroiminodihydantoin and 8-oxo-2'-deoxyguanosine. Chemical research in toxicology 20050701
Effects of long-term treatment with mizoribine in patients with proliferative lupus nephritis. Clinical nephrology 20050701
Adenosine and purine nucleosides prevent the disruption of mitochondrial transmembrane potential by peroxynitrite in rat primary astrocytes. Archives of pharmacal research 20050701
Virulence deficiency caused by a transposon insertion in the purH gene of Xanthomonas oryzae pv. oryzae. Canadian journal of microbiology 20050701
Loss of ecto-5'nucleotidase from porcine endothelial cells after exposure to human blood: Implications for xenotransplantation. Biochimica et biophysica acta 20050630
Modeling of purine derivatives transport across cell membranes based on their partition coefficient determination and quantum chemical calculations. Journal of medicinal chemistry 20050630
Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9). The Journal of biological chemistry 20050624
Role of an active site adenine in hairpin ribozyme catalysis. Journal of molecular biology 20050624
Regulation and activity of cytosolic 5'-nucleotidase II. A bifunctional allosteric enzyme of the Haloacid Dehalogenase superfamily involved in cellular metabolism. FEBS letters 20050620
Identification of a subversive substrate of Trichomonas vaginalis purine nucleoside phosphorylase and the crystal structure of the enzyme-substrate complex. The Journal of biological chemistry 20050610
Activation of alternative oxidase and uncoupling protein lowers hydrogen peroxide formation in amoeba Acanthamoeba castellanii mitochondria. FEBS letters 20050606
Hepatoprotective effects of Hibiscus, Rosmarinus and Salvia on azathioprine-induced toxicity in rats. Life sciences 20050603
Theoretical study of cisplatin binding to DNA: the importance of initial complex stabilization. The journal of physical chemistry. B 20050602
Reduction of arsenate to arsenite by human erythrocyte lysate and rat liver cytosol - characterization of a glutathione- and NAD-dependent arsenate reduction linked to glycolysis. Toxicological sciences : an official journal of the Society of Toxicology 20050601
Purine nucleoside-mediated protection of chemical hypoxia-induced neuronal injuries involves p42/44 MAPK activation. Neurochemistry international 20050601
Regulation of purine biosynthesis by a eukaryotic-type kinase in Streptococcus agalactiae. Molecular microbiology 20050601
Amphioxus allantoicase: molecular cloning, expression and enzymatic activity. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050601
Transglycosylation: a mechanism for RNA modification (and editing?). Bioorganic chemistry 20050601
Identification of the main oxidation products of 8-methoxy-2'-deoxyguanosine by singlet molecular oxygen. Free radical biology & medicine 20050601
Radiation-induced hydroxyl addition to purine molecules: EPR and ENDOR study of hypoxanthine hydrochloride monohydrate single crystals. Radiation research 20050601
Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis. Pharmacological reviews 20050601
IMP dehydrogenase from the protozoan parasite Toxoplasma gondii. Antimicrobial agents and chemotherapy 20050601
Renal urate handling: clinical relevance of recent advances. Current rheumatology reports 20050601
Developmentally restricted genetic determinants of human arsenic metabolism: association between urinary methylated arsenic and CYT19 polymorphisms in children. Environmental health perspectives 20050601
Adenine nucleotides in snail muscles as one of biomarkers of fluoride toxicity. Journal of environmental monitoring : JEM 20050601
Altered membrane NTPase activity in Lesch-Nyhan disease fibroblasts: comparison with HPRT knockout mice and HPRT-deficient cell lines. Journal of neurochemistry 20050601
Effect of ethanol on metabolism of purine bases (hypoxanthine, xanthine, and uric acid). Clinica chimica acta; international journal of clinical chemistry 20050601
The plant Mo-hydroxylases aldehyde oxidase and xanthine dehydrogenase have distinct reactive oxygen species signatures and are induced by drought and abscisic acid. The Plant journal : for cell and molecular biology 20050601
Outcomes of patients with acute leukaemia who relapsed after reduced-intensity stem cell transplantation from HLA-identical or one antigen-mismatched related donors. British journal of haematology 20050601
Adenylyl cyclase Rv0386 from Mycobacterium tuberculosis H37Rv uses a novel mode for substrate selection. The FEBS journal 20050601
TRAP220 is modulated by the antineoplastic agent 6-Mercaptopurine, and mediates the activation of the NR4A subgroup of nuclear receptors. Journal of molecular endocrinology 20050601
Synthesis, characterization, and 32p-postlabeling analysis of DNA adducts derived from the environmental contaminant 3-nitrobenzanthrone. Chemical research in toxicology 20050601
[Comparative proteomics research on removing of large invasive plasmid pINV of Shigella flexneri 2a strain 2457T]. Wei sheng wu xue bao = Acta microbiologica Sinica 20050601
Urinary excretion of purine derivatives in Bos indicus x Bos taurus crossbred cattle. The British journal of nutrition 20050601
Screening of catalytically active microorganisms for the synthesis of 6-modified purine nucleosides. Biotechnology letters 20050601
[Study of crystalluria in diabetic patients]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20050601
Downregulation of glial scarring after brain injury: the effect of purine nucleoside analogue ribavirin. Annals of the New York Academy of Sciences 20050601
By the way, doctor. I have gout. I've read that foods high in purine can aggravate the condition. What is purine, and how can I reduce it in my diet. Harvard women's health watch 20050601
[Hyperuricemia and disorders in content of amino acids-purine precursors in patients with autoimmune diseases and gout]. Likars'ka sprava 20050601
General acid catalysis by the hepatitis delta virus ribozyme. Nature chemical biology 20050601
Responses of the ciliates Tetrahymena and Paramecium to external ATP and GTP. Purinergic signalling 20050601
Neuroprotection by adenosine in the brain: From A(1) receptor activation to A (2A) receptor blockade. Purinergic signalling 20050601
Guanosine stimulates neurite outgrowth in PC12 cells via activation of heme oxygenase and cyclic GMP. Purinergic signalling 20050601
2- and 8-alkynyl-9-ethyladenines: Synthesis and biological activity at human and rat adenosine receptors. Purinergic signalling 20050601
Structure-activity relationships of dinucleotides: Potent and selective agonists of P2Y receptors. Purinergic signalling 20050601
Simultaneous determination of 16 purine derivatives in urinary calculi by gradient reversed-phase high-performance liquid chromatography with UV detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050525
Unusual usage of wobble modifications in mitochondrial tRNAs of the nematode Ascaris suum. FEBS letters 20050523
Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050520
Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway. Bioorganic & medicinal chemistry 20050516
Synthesis and biological evaluation of alpha- and gamma-carboxamide derivatives of 10-CF3CO-DDACTHF. Bioorganic & medicinal chemistry 20050516
6-Benzylthioinosine analogues as subversive substrate of Toxoplasma gondii adenosine kinase: activities and selective toxicities. Biochemical pharmacology 20050515
Single DNA molecules as probes of chromatographic surfaces. Analytical chemistry 20050515
Microelectrode biosensor for real-time measurement of ATP in biological tissue. Analytical chemistry 20050515
Comprehensive assignment of mass spectral signatures from individual Bacillus atrophaeus spores in matrix-free laser desorption/ionization bioaerosol mass spectrometry. Analytical chemistry 20050515
Structural rationale for the affinity of pico- and femtomolar transition state analogues of Escherichia coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. The Journal of biological chemistry 20050506
Adenosine kinase inhibitors. 4. 6,8-Disubstituted purine nucleoside derivatives. Synthesis, conformation, and enzyme inhibition. Journal of medicinal chemistry 20050505
Deactivation of triplet-excited riboflavin by purine derivatives: important role of uric acid in light-induced oxidation of milk sensitized by riboflavin. Journal of agricultural and food chemistry 20050504
Visible light (>395 nm) causes micronuclei formation in mammalian cells without generation of cyclobutane pyrimidine dimers. Mutation research 20050502
Optimization of purine based PDE1/PDE5 inhibitors to a potent and selective PDE5 inhibitor for the treatment of male ED. Bioorganic & medicinal chemistry letters 20050502
Transcriptional tumor-selective promoter targeting of E. coli purine nucleoside phosphorylase for pancreatic cancer suicide gene therapy. The journal of gene medicine 20050501
Eradication of minimal residual disease in B-cell chronic lymphocytic leukemia after alemtuzumab therapy is associated with prolonged survival. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050501
Capillary zone electrophoretic studies of interactions of some quaternary isoquinoline alkaloids with DNA constituents and DNA. Electrophoresis 20050501
In vitro cytotoxic effect of proteasome inhibitor bortezomib in combination with purine nucleoside analogues on chronic lymphocytic leukaemia cells. European journal of haematology 20050501
Immunosuppressive efficacy of mycophenolate mofetil when compared with azathioprine and mizoribine against peripheral lymphocytes from renal transplant recipients. Transplant international : official journal of the European Society for Organ Transplantation 20050501
Three Prochlorococcus cyanophage genomes: signature features and ecological interpretations. PLoS biology 20050501
Systems rebalancing of metabolism in response to sulfur deprivation, as revealed by metabolome analysis of Arabidopsis plants. Plant physiology 20050501
Assessment of the genotoxic potential of nitric oxide-induced guanine lesions by in vitro reactions with Escherichia coli DNA polymerase I. Mutagenesis 20050501
Stopped-flow studies of guanine binding by calf spleen purine nucleoside phosphorylase. Biophysical chemistry 20050501
Functional characterization and expression analysis of a gene, OsENT2, encoding an equilibrative nucleoside transporter in rice suggest a function in cytokinin transport. Plant physiology 20050501
Lesch-Nyhan disease in a female with a clinically normal monozygotic twin. Molecular genetics and metabolism 20050501
Prolymphocytic leukemia. Current treatment options in oncology 20050501
The MTHFR C677T polymorphism and colorectal cancer: the multiethnic cohort study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050501
Purine nucleosides stimulate Na/K ATPase, and prolong survival in hemorrhagic shock. The Journal of trauma 20050501
[Molecular studies of vardenafil]. Zhonghua nan ke xue = National journal of andrology 20050501
[Mizoribine]. Nihon rinsho. Japanese journal of clinical medicine 20050501
Clofarabine. Nature reviews. Drug discovery 20050501
Azathioprine induced nodular regenerative hyperplasia in IBD patients. Gastroenterologie clinique et biologique 20050501
Anicemycin, a new inhibitor of anchorage-independent growth of tumor cells from Streptomyces sp. TP-A0648. The Journal of antibiotics 20050501
Structure of purine nucleoside phosphorylase (DeoD) from Bacillus anthracis. Acta crystallographica. Section F, Structural biology and crystallization communications 20050501
Genetically selected cyclic-peptide inhibitors of AICAR transformylase homodimerization. Angewandte Chemie (International ed. in English) 20050429
The mechanism of selective purine C-nitration revealed: NMR studies demonstrate formation and radical rearrangement of an N7-nitramine intermediate. Journal of the American Chemical Society 20050427
Investigation of systemic folate status, impact of alcohol intake and levels of DNA damage in mononuclear cells of breast cancer patients. British journal of cancer 20050425
Escherichia coli purine nucleoside phosphorylase II, the product of the xapA gene. Journal of molecular biology 20050422
Evaluation of 8-arylsulfanyl, 8-arylsulfoxyl, and 8-arylsulfonyl adenine derivatives as inhibitors of the heat shock protein 90. Journal of medicinal chemistry 20050421
Substrate-assisted leaving group activation in enzyme-catalyzed N-glycosidic bond cleavage. The Journal of biological chemistry 20050415
31P NMR and genetic analysis establish hinT as the only Escherchia coli purine nucleoside phosphoramidase and as essential for growth under high salt conditions. The Journal of biological chemistry 20050415
Involvement of uracil nucleotides in protection of cardiomyocytes from hypoxic stress. Biochemical pharmacology 20050415
Calcium activates erythrocyte AMP deaminase [isoform E (AMPD3)] through a protein-protein interaction between calmodulin and the N-terminal domain of the AMPD3 polypeptide. Biochemistry 20050412
Evidence for the involvement of cytosolic 5'-nucleotidase (cN-II) in the synthesis of guanine nucleotides from xanthosine. The Journal of biological chemistry 20050408
Synthesis, biological activity, and SAR of antimycobacterial 9-aryl-, 9-arylsulfonyl-, and 9-benzyl-6-(2-furyl)purines. Journal of medicinal chemistry 20050407
Residue 33 of human equilibrative nucleoside transporter 2 is a functionally important component of both the dipyridamole and nucleoside binding sites. Molecular pharmacology 20050401
Interactions of carboxypeptidase G2 with 6S-leucovorin and 6R-leucovorin in vitro: implications for the application in case of methotrexate intoxications. Cancer chemotherapy and pharmacology 20050401
Methylthioadenosine phosphorylase gene is silenced by promoter hypermethylation in human lymphoma cell line DHL-9: another mechanism of enzyme deficiency. International journal of oncology 20050401
Synthesis and immunobiological activity of base substituted 2-amino-3-(purin-9-yl)propanoic acid derivatives. Bioorganic & medicinal chemistry 20050401
Promising treatment of autoimmune hepatitis with 6-thioguanine after adverse events on azathioprine. European journal of gastroenterology & hepatology 20050401
Stability of 3' double nucleotide overhangs that model the 3' ends of siRNA. RNA (New York, N.Y.) 20050401
Molecular physiology of urate transport. Physiology (Bethesda, Md.) 20050401
Phenotypic characterization of Rice Cluster III archaea without prior isolation by applying quantitative polymerase chain reaction to an enrichment culture. Environmental microbiology 20050401
Pemetrexed (Alimta) in small cell lung cancer. Seminars in oncology 20050401
The evolving role of pemetrexed (Alimta) in lung cancer. Seminars in oncology 20050401
Three emerging new drugs for NSCLC: pemetrexed, bortezomib, and cetuximab. The oncologist 20050401
8-Amino-adenosine induces loss of phosphorylation of p38 mitogen-activated protein kinase, extracellular signal-regulated kinase 1/2, and Akt kinase: role in induction of apoptosis in multiple myeloma. Molecular cancer therapeutics 20050401
6-substituted purines as inhibitors of 15-lipoxygenase; a structure-activity study. Archiv der Pharmazie 20050401
Activity of purine catabolism enzymes during the reproductive cycle of male and female brown trout (Salmo trutta). Annals of the New York Academy of Sciences 20050401
Mutations in PurBox1 of the Bacillus subtilis pur operon control site affect adenine-regulated expression in vivo. Science in China. Series C, Life sciences 20050401
An investigation of prebiotic purine synthesis from the hydrolysis of HCN polymers. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20050401
Effects of 6-mercaptopurine treatment on sperm production and reproductive performance: a study in male mice. Scandinavian journal of gastroenterology 20050401
A Methanocaldococcus jannaschii archaeal signature gene encodes for a 5-formaminoimidazole-4-carboxamide-1-beta-D-ribofuranosyl 5'-monophosphate synthetase. A new enzyme in purine biosynthesis. The Journal of biological chemistry 20050325
Nitric oxide-dependent allosteric inhibitory role of a second nucleotide binding site in soluble guanylyl cyclase. The Journal of biological chemistry 20050325
Development and validation of a liquid chromatography and tandem mass spectrometry method for determination of roscovitine in plasma and urine samples utilizing on-line sample preparation. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325
Inclining the purine base binding plane in protein kinase CK2 by exchanging the flanking side-chains generates a preference for ATP as a cosubstrate. Journal of molecular biology 20050325
Paradoxical CD4+ T-cell decline in HIV-infected patients with complete virus suppression taking tenofovir and didanosine. AIDS (London, England) 20050324
Sequence-selective interaction of the minor-groove interstrand cross-linking agent SJG-136 with naked and cellular DNA: footprinting and enzyme inhibition studies. Biochemistry 20050322
Synthesis and antimycobacterial activity of agelasine E and analogs. Organic & biomolecular chemistry 20050321
Fluoro, alkylsulfanyl, and alkylsulfonyl leaving groups in suzuki cross-coupling reactions of purine 2'-deoxynucleosides and nucleosides. Organic letters 20050317
Binding of six nucleotide cofactors to the hexameric helicase RepA protein of plasmid RSF1010. 2. Base specificity, nucleotide structure, magnesium, and salt effect on the cooperative binding of the cofactors. Biochemistry 20050315
Casein kinase 2 regulates both apoptosis and the cell cycle following DNA damage induced by 6-thioguanine. Clinical cancer research : an official journal of the American Association for Cancer Research 20050315
Targeting a novel Plasmodium falciparum purine recycling pathway with specific immucillins. The Journal of biological chemistry 20050311
Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK. The Journal of biological chemistry 20050304
Disruption of the mthfd1 gene reveals a monofunctional 10-formyltetrahydrofolate synthetase in mammalian mitochondria. The Journal of biological chemistry 20050304
Selectivity of febuxostat, a novel non-purine inhibitor of xanthine oxidase/xanthine dehydrogenase. Life sciences 20050304
'Molecular chameleons'. Design and synthesis of a second series of flexible nucleosides. The Journal of organic chemistry 20050304
Home-based exercise training modulates pro-oxidant substrates in patients with chronic heart failure. European journal of heart failure 20050302
In vivo inosine protects alveolar epithelial type 2 cells against hyperoxia-induced DNA damage through MAP kinase signaling. American journal of physiology. Lung cellular and molecular physiology 20050301
Identification and characterization of purine nucleoside transporters from Crithidia fasciculata. Molecular and biochemical parasitology 20050301
Limitation of podocyte proliferation improves renal function in experimental crescentic glomerulonephritis. Kidney international 20050301
Solution structure of an RNA internal loop with three consecutive sheared GA pairs. Biochemistry 20050301
Local conformational changes induced in B-DNA by ethidium intercalation. Biochemistry 20050301
Topolins and hydroxylated thidiazuron derivatives are substrates of cytokinin O-glucosyltransferase with position specificity related to receptor recognition. Plant physiology 20050301
How many functional transport pathways does Plasmodium falciparum induce in the membrane of its host erythrocyte? Trends in parasitology 20050301
Use of odd and branched-chain fatty acids in rumen contents and milk as a potential microbial marker. Journal of dairy science 20050301
Urinary trivalent methylated arsenic species in a population chronically exposed to inorganic arsenic. Environmental health perspectives 20050301
Chronic lymphocytic leukemia: novel prognostic factors and their relevance for risk-adapted therapeutic strategies. Haematologica 20050301
Metal complexes with aromatic N-containing ligands as potential agents in cancer treatment. Current medicinal chemistry. Anti-cancer agents 20050301
[Progress in therapeutic strategy for malignant lymphoma]. Gan to kagaku ryoho. Cancer & chemotherapy 20050301
Identification of the first pyrimidine nucleobase transporter in Leishmania: similarities with the Trypanosoma brucei U1 transporter and antileishmanial activity of uracil analogues. Parasitology 20050301
Antibiotic-mediated chemoprotection enhances adaptation of E. coli PNP for herpes simplex virus-based glioma therapy. Human gene therapy 20050301
[News in therapeutic management of chronic lymphoid leukemia]. Bulletin du cancer 20050301
Purine level regulation during energy depletion associated with graded excitatory stimulation in brain. Neurological research 20050301
Astrocytes and neurons: different roles in regulating adenosine levels. Neurological research 20050301
Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene. Pharmacogenetics and genomics 20050301
The origin and evolution of operons: the piecewise building of the proteobacterial histidine operon. Journal of molecular evolution 20050301
Effects of Rebixiao granules on blood uric acid in patients with repeatedly attacking acute gouty arthritis. Chinese journal of integrative medicine 20050301
Heart failure, oxidative stress and allopurinol. Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace 20050301
Advances in the diagnosis and treatment of chronic lymphocytic leukemia. Hematological oncology 20050301
New catalytic mechanism for human purine nucleoside phosphorylase. Biochemical and biophysical research communications 20050218
Exploring human adenosine A3 receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety. Bioorganic & medicinal chemistry 20050215
Aqueous extract of Ilex paraguariensis decreases nucleotide hydrolysis in rat blood serum. Journal of ethnopharmacology 20050210
Synthesis and biological testing of purine derivatives as potential ATP-competitive kinase inhibitors. Journal of medicinal chemistry 20050210
Solvatochromism of a novel betaine dye derived from purine. The journal of physical chemistry. A 20050210
Human organic anion transporter MRP4 (ABCC4) is an efflux pump for the purine end metabolite urate with multiple allosteric substrate binding sites. American journal of physiology. Renal physiology 20050201
The place of cladribine in the treatment of chronic lymphocytic leukemia: a 10-year experience in Poland. Annals of hematology 20050201
Dynamics and stability of GCAA tetraloops with 2-aminopurine and purine substitutions. Journal of biomolecular structure & dynamics 20050201
Purine- and pyrimidine-induced responses and P2Y receptor characterization in the hamster proximal urethra. British journal of pharmacology 20050201
The snRNP 15.5K protein folds its cognate K-turn RNA: a combined theoretical and biochemical study. RNA (New York, N.Y.) 20050201
Allosteric mechanisms in ACT domain containing enzymes involved in amino acid metabolism. Amino acids 20050201
Stereoselective synthesis of 9-beta-d-arabianofuranosyl guanine and 2-amino-9-(beta-d-arabianofuranosyl)purine. Bioorganic & medicinal chemistry letters 20050201
Synthesis of 9-(2-beta-C-methyl-beta-d-ribofuranosyl)-6-substituted purine derivatives as inhibitors of HCV RNA replication. Bioorganic & medicinal chemistry letters 20050201
Uridine adenosine tetraphosphate: a novel endothelium- derived vasoconstrictive factor. Nature medicine 20050201
ACP Best Practice No 181: Chemical pathology clinical investigation and management of nephrolithiasis. Journal of clinical pathology 20050201
Induction of CCAAT/enhancer binding protein-delta by cytokinins, but not by retinoic acid, during granulocytic differentiation of human myeloid leukaemia cells. British journal of haematology 20050201
Trypanosoma brucei: expression of multiple purine transporters prevents the development of allopurinol resistance. Experimental parasitology 20050201
Beneficial antipsychotic effects of allopurinol as add-on therapy for schizophrenia: a double blind, randomized and placebo controlled trial. Progress in neuro-psychopharmacology & biological psychiatry 20050201
3-Bromo-1-(2-deoxy-beta-D-erythro-pentofuranosyl)-1H-pyrazolo[3,4-d]pyrimidine-4,6-diamine: a nucleoside which strongly enhances DNA duplex stability. Acta crystallographica. Section C, Crystal structure communications 20050201
Loss of reduced folate carrier function and folate depletion result in enhanced pemetrexed inhibition of purine synthesis. Clinical cancer research : an official journal of the American Association for Cancer Research 20050201
Therapy of chronic lymphocytic leukemia with purine analogs and monoclonal antibodies. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20050201
Hairy cell leukemia: survival and relapse. Long-term follow-up of purine analog-based therapy and approach for relapsed disease. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20050201
First self. Emerging infectious diseases 20050201
[Researches on the establishment of chronic nephropathy models and the effect of TCM on these models]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20050201
Expression analysis onto microarrays of randomly selected cDNA clones highlights HOXB13 as a marker of human prostate cancer. British journal of cancer 20050131
Detection of Ki-ras mutations in tissue and plasma samples of patients with pancreatic cancer using PNA-mediated PCR clamping and hybridisation probes. British journal of cancer 20050131
Synthesis and antiviral evaluation of cis-substituted cyclohexenyl and cyclohexanyl nucleosides. Journal of medicinal chemistry 20050127
Hemodynamic and respiratory responses to microinjection of ATP into the intermediate and caudal NTS of awake rats. Brain research 20050125
Hydrogen bonding and covalent effects in binding of cisplatin to purine bases: ab initio and atoms in molecules studies. Inorganic chemistry 20050124
Second-site suppression of a nonfunctional mutation within the Leishmania donovani inosine-guanosine transporter. The Journal of biological chemistry 20050121
Relation of enzyme activity to local/global stability of murine adenosine deaminase: 19F NMR studies. Journal of molecular biology 20050121
Transient expression and flux changes during a shift from high to low riboflavin production in continuous cultures of Bacillus subtilis. Biotechnology and bioengineering 20050120
Synthesis and EPR studies of 2-N-tert-butylaminoxylpurine derivatives. Organic letters 20050120
Active site plasticity of endonuclease V from Salmonella typhimurium. Biochemistry 20050118
Mechanism of action of Escherichia coli phosphoribosylaminoimidazolesuccinocarboxamide synthetase. Biochemistry 20050118
Clinical anticancer drug development: targeting the cyclin-dependent kinases. British journal of cancer 20050117
The fluorescence enhancement effect of Tb-Gd-adenosine triphosphate-phen system and its analytical application. Talanta 20050115
Crystal structure of human PNP complexed with hypoxanthine and sulfate ion. Biochemical and biophysical research communications 20050114
Nucleotides and pronucleotides of 2,2-bis(hydroxymethyl)methylenecyclopropane analogues of purine nucleosides: synthesis and antiviral activity. Journal of medicinal chemistry 20050113
How flexible are fleximer nucleobases? A computational study. The journal of physical chemistry. A 20050113
The N6-methyl group of adenine further increases the BI stability of DNA compared to C5-methyl groups. The journal of physical chemistry. B 20050113
Nanocrystal-based bioelectronic coding of single nucleotide polymorphisms. Journal of the American Chemical Society 20050112
Synthesis of oligonucleotides containing Fapy.dG (N(6)-(2-deoxy-alpha,beta-D-erythropentofuranosyl)-2,6-diamino-4-hydroxy-5-formamidopyrimidine) using a 5'-dimethoxytrityl dinucleotide phosphoramidite. The Journal of organic chemistry 20050107
'Molecular chameleons'. Design and synthesis of C-4-substituted imidazole fleximers. Organic letters 20050106
The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation. Bioorganic & medicinal chemistry 20050103
shRNA-mediated RNA interference as a tool for genetic synthetic lethality screening in mouse embryo fibroblasts. FEBS letters 20050103
Base-modified oligonucleotides with increased duplex stability: pyrazolo[3,4-d] pyrimidines replacing purines. Methods in molecular biology (Clifton, N.J.) 20050101
HeLa cell nucleus, a source of thymidine for Trichomonas vaginalis growing in vitro. The international journal of biochemistry & cell biology 20050101
Molecular analysis of mutations in the human HPRT gene. Methods in molecular biology (Clifton, N.J.) 20050101
Splenic marginal zone lymphoma. Blood reviews 20050101
Enzymatic transition states: thermodynamics, dynamics and analogue design. Archives of biochemistry and biophysics 20050101
Protective effect of adenosine and purine nucleos(t)ides against the death by hydrogen peroxide and glucose deprivation in rat primary astrocytes. Neuroscience research 20050101
Purine metabolism and hyperuricemic states. 'The point of view of the rheumatologist'. Contributions to nephrology 20050101
Hyperuricemia and bone marrow transplantation. Contributions to nephrology 20050101
Rasburicase therapy in acute hyperuricemia and renal dysfunction. Contributions to nephrology 20050101
8-OxoA inhibits the incision of an AP site by the DNA glycosylases Fpg, Nth and the AP endonuclease HAP1. Radiation research 20050101
Growth inhibition of Listeria monocytogenes by a nonbacteriocinogenic Carnobacterium piscicola. Journal of applied microbiology 20050101
Addicted to death: invasive cancer and the immune response to unscheduled cell death. Journal of immunotherapy (Hagerstown, Md. : 1997) 20050101
Taxonomic distribution and quantitative analysis of free purine and pyrimidine nucleosides in snake venoms. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050101
Proapoptotic activity of alemtuzumab alone and in combination with rituximab or purine nucleoside analogues in chronic lymphocytic leukemia cells. Leukemia & lymphoma 20050101
The structure of a rigorously conserved RNA element within the SARS virus genome. PLoS biology 20050101
Differences in codon bias cannot explain differences in translational power among microbes. BMC bioinformatics 20050101
Microarray-based resequencing of multiple Bacillus anthracis isolates. Genome biology 20050101
Computational prediction of human metabolic pathways from the complete human genome. Genome biology 20050101
Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Genome biology 20050101
Generation of predictive pharmacophore model for SARS-coronavirus main proteinase. European journal of medicinal chemistry 20050101
Mycophenolate mofetil modulates adhesion receptors of the beta1 integrin family on tumor cells: impact on tumor recurrence and malignancy. BMC cancer 20050101
Selection and characterization of a promoter for expression of single-copy recombinant genes in Gram-positive bacteria. BMC biotechnology 20050101
Metabolism and pharmacokinetics of the cyclin-dependent kinase inhibitor R-roscovitine in the mouse. Molecular cancer therapeutics 20050101
Hereditary hyperuricemia and renal disease. Seminars in nephrology 20050101
Molecular models of NS3 protease variants of the Hepatitis C virus. BMC structural biology 20050101
Riboswitch structures: purine ligands replace tertiary contacts. Chemistry & biology 20050101
Adenosine deaminase deficiency: metabolic basis of immune deficiency and pulmonary inflammation. Advances in immunology 20050101
Severe and steroid-resistant Crohn's disease. Digestion 20050101
Hypothesized deficiency of guanine-based purines may contribute to abnormalities of neurodevelopment, neuromodulation, and neurotransmission in Lesch-Nyhan syndrome. Clinical neuropharmacology 20050101
Synthesis and biological evaluation of 2- and 7-substituted 9-deazaadenosine analogues. Nucleosides, nucleotides & nucleic acids 20050101
Molecular strategies to inhibit HIV-1 replication. Retrovirology 20050101
Using purine skews to predict genes in AT-rich poxviruses. BMC genomics 20050101
Functional analysis of genetic variants in the human concentrative nucleoside transporter 3 (CNT3; SLC28A3). The pharmacogenomics journal 20050101
A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis. Arthritis research & therapy 20050101
Application of population pharmacokinetics to cladribine. BMC pharmacology 20050101
Electrospray ionization mass spectrometric study of purine base-cisplatin complexes. Rapid communications in mass spectrometry : RCM 20050101
Data mining of the transcriptome of Plasmodium falciparum: the pentose phosphate pathway and ancillary processes. Malaria journal 20050101
The 'permeome' of the malaria parasite: an overview of the membrane transport proteins of Plasmodium falciparum. Genome biology 20050101
Modulation of cytokine release by purine receptors in patients with rheumatoid arthritis. Clinical and experimental rheumatology 20050101
Accelerated probabilistic inference of RNA structure evolution. BMC bioinformatics 20050101
Managing malignancy-associated hyperuricemia with rasburicase. The journal of supportive oncology 20050101
In silico studies toward the discovery of new anti-HIV nucleoside compounds through the use of TOPS-MODE and 2D/3D connectivity indices. 2. Purine derivatives. Journal of chemical information and modeling 20050101
Abacavir, efavirenz, didanosine, with or without hydroxyurea, in HIV-infected adults failing initial nucleoside/protease inhibitor-containing regimens. BMC infectious diseases 20050101
Fludarabine phosphate may be useful in the treatment of graft-versus-host disease. Medical hypotheses 20050101
Evolutionary distance estimation and fidelity of pair wise sequence alignment. BMC bioinformatics 20050101
[Disfunction of thyroid gland at experimental hyperuricemia]. Biomeditsinskaia khimiia 20050101
Investigating hookworm genomes by comparative analysis of two Ancylostoma species. BMC genomics 20050101
Guanylic nucleotide starvation affects Saccharomyces cerevisiae mother-daughter separation and may be a signal for entry into quiescence. BMC cell biology 20050101
Rational polynomial representation of ribonucleotide reductase activity. BMC biochemistry 20050101
Preparation of a fully substituted purine library. Journal of combinatorial chemistry 20050101
[Applicability of fozinopril for correction of basic manifestations of metabolic syndrome in women with arterial hypertension]. Terapevticheskii arkhiv 20050101
Changes in the transcriptional profile of transporters in the intestine along the anterior-posterior and crypt-villus axes. BMC genomics 20050101
Confocal fluorescence imaging of photosensitized DNA denaturation in cell nuclei. Photochemistry and photobiology 20050101
P2Y1 and cysteinyl leukotriene receptors mediate purine and cysteinyl leukotriene co-release in primary cultures of rat microglia. International journal of immunopathology and pharmacology 20050101
Neutrophil chemotaxis: autotaxin induced attenuation of purine/pyrimidine signaling precede the overexpression of Integrin(s). Medical hypotheses 20050101
HinT proteins and their putative interaction partners in Mollicutes and Chlamydiaceae. BMC microbiology 20050101
Adenovirus-mediated interleukin-12 gene transfer combined with cytosine deaminase followed by 5-fluorocytosine treatment exerts potent antitumor activity in Renca tumor-bearing mice. BMC cancer 20050101
Synthesis and biodistribution of [11C]adenosine 5'-monophosphate ([11C]AMP). Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20050101
Genetic islands of Streptococcus agalactiae strains NEM316 and 2603VR and their presence in other Group B streptococcal strains. BMC microbiology 20050101
Metabolic effects of novel N-1-sulfonylpyrimidine derivatives on human colon carcinoma cells. Farmaco (Societa chimica italiana : 1989) 20050101
Genome-wide screening for genes whose deletions confer sensitivity to mutagenic purine base analogs in yeast. BMC genetics 20050101
[Enzymes of purine nucleotide metabolism in assessment of the functional competence of the immune system]. Biomeditsinskaia khimiia 20050101
Expression of human AID in yeast induces mutations in context similar to the context of somatic hypermutation at G-C pairs in immunoglobulin genes. BMC immunology 20050101
Severe skin reaction related to mycophenolate mofetil for myasthenia gravis. Clinical neuropharmacology 20050101
Modulation of p53 activity by IkappaBalpha: evidence suggesting a common phylogeny between NF-kappaB and p53 transcription factors. BMC immunology 20050101
[Severity of a female gout course]. Terapevticheskii arkhiv 20050101
The genomics of probiotic intestinal microorganisms. Genome biology 20050101
[Polymethylene derivatives of nucleic bases with omega-functional groups: IV. [7-(2-oxocyclohexyl)-7-oxoheptyl]purines]. Bioorganicheskaia khimiia 20050101
Parallel solution-phase synthesis of a 2,6,8,9-tetrasubstituted purine library via a sulfur intermediate. Journal of combinatorial chemistry 20050101
The purine nucleotide content in human leukemia cell lines. Cellular & molecular biology letters 20050101
Purine metabolism in pigs and humans and its implications for xenotransplantation. Nucleosides, nucleotides & nucleic acids 20050101
A microarray study of MPP+-treated PC12 Cells: Mechanisms of toxicity (MOT) analysis using bioinformatics tools. BMC bioinformatics 20050101
Resistance to aspirin is increased by ST-elevation myocardial infarction and correlates with adenosine diphosphate levels. Thrombosis journal 20050101
Folate system correlations in DNA microarray data. BMC cancer 20050101
Evolution of selenium utilization traits. Genome biology 20050101
Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria. Genome biology 20050101
Ischemic preconditioning attenuates portal venous plasma concentrations of purines following warm liver ischemia in man. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20050101
Bystander effects in UV-induced genomic instability: antioxidants inhibit delayed mutagenesis induced by ultraviolet A and B radiation. Journal of carcinogenesis 20050101
Cross genome phylogenetic analysis of human and Drosophila G protein-coupled receptors: application to functional annotation of orphan receptors. BMC genomics 20050101
Inhibition of glycinamide ribonucleotide formyltransferase results in selective inhibition of macrophage cytokine secretion in vitro and in vivo efficacy in rat adjuvant arthritis. Clinical and experimental rheumatology 20050101
Three subsets of sequence complexity and their relevance to biopolymeric information. Theoretical biology & medical modelling 20050101
Cloning and functional characterization of two bacterial members of the NAT/NCS2 family in Escherichia coli. Molecular membrane biology 20050101
Comparative substrate recognition by bacterial and fungal purine transporters of the NAT/NCS2 family. Molecular membrane biology 20050101
Enhanced efficacy of gemcitabine in combination with anti-CD20 monoclonal antibody against CD20+ non-Hodgkin's lymphoma cell lines in vitro and in scid mice. BMC cancer 20050101
A case report of Merkel cell carcinoma on chronic lymphocytic leukemia: differential diagnosis of coexisting lymphadenopathy and indications for early aggressive treatment. BMC cancer 20050101
Clofarabine: in pediatric patients with acute lymphoblastic leukemia. Paediatric drugs 20050101
Antitumor polycyclic acridines. Part 16. Triplex DNA as a target for DNA-binding polycyclic acridine derivatives. Oncology research 20050101
[Nuclease biosynthesis and growth of Serratia marcescens in the presence of 2-(p-aminobenzenesulfonamide)-thiazole]. Mikrobiologiia 20050101
Organic acid toxicity, tolerance, and production in Escherichia coli biorefining applications. Microbial cell factories 20050101
Fundamental roles of reactive oxygen species and protective mechanisms in the female reproductive system. Reproductive biology and endocrinology : RB&E 20050101
[Diagnostic aspects of familial juvenile hyperuriceamic nephropathy]. Casopis lekaru ceskych 20050101
Disorders of purine and pyrimidine metabolism. Molecular genetics and metabolism 20050101
Mitochondrial-encoded membrane protein transcripts are pyrimidine-rich while soluble protein transcripts and ribosomal RNA are purine-rich. BMC genomics 20050101
Digital drug discovery. Genome biology 20050101
Separation of genomic DNA from plasmid DNA by selective renaturation with immobilized metal affinity capture. Biotechnology progress 20050101
Evidence of recombination among early-vaccination era measles virus strains. BMC evolutionary biology 20050101
The distribution of SNPs in human gene regulatory regions. BMC genomics 20050101
Evolutionary relationship and application of a superfamily of cyclic amidohydrolase enzymes. Chemical record (New York, N.Y.) 20050101
Regression of long standing anorexia nervosa following acute renal failure caused by gentamicin intoxication. Przeglad lekarski 20050101
Evolutionary, structural and functional relationships revealed by comparative analysis of syntenic genes in Rhizobiales. BMC evolutionary biology 20050101
Comparative genomics of Thermus thermophilus and Deinococcus radiodurans: divergent routes of adaptation to thermophily and radiation resistance. BMC evolutionary biology 20050101
HPRT deficiency as the cause of ESRD in a 24-year-old patient: a very rare presentation of the disorder. Journal of nephrology 20050101
Synthesis of complex nucleoside antibiotics. Nucleosides, nucleotides & nucleic acids 20050101
Spectroscopic and kinetic studies of interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, and its 9-(2-phosphonylmethoxyethyl) derivative. Nucleosides, nucleotides & nucleic acids 20050101
Kinetic model of oxidation catalyzed by xanthine oxidase-the final enzyme in degradation of purine nucleosides and nucleotides. Nucleosides, nucleotides & nucleic acids 20050101
Kinetic properties of Cellulomonas sp. purine nucleoside phosphorylase with typical and non-typical substrates: implications for the reaction mechanism. Nucleosides, nucleotides & nucleic acids 20050101
Synthesis and antitumor activity of 5-bromo-1-mesyluracil. Nucleosides, nucleotides & nucleic acids 20050101
Synthesis of 2'-C-methyl-beta-D-ribofuranosylimidazo [4,5-d]-pyridazine derivatives (2-aza-3-deazapurine nucleoside analogues). Nucleosides, nucleotides & nucleic acids 20050101
Ring-expanded analogues of natural oxetanocin: (+) and (-) hydroxymethyl isodideoxyadenosine. Nucleosides, nucleotides & nucleic acids 20050101
Synthesis of racemic and enantiomeric 3-pyrrolidinyl derivatives of purine and pyrimidine nucleobases. Nucleosides, nucleotides & nucleic acids 20050101
Bis(tBuSATE) phosphotriester prodrugs of 8-azaguanosine and 6-methylpurine riboside; bis(pom) phosphotriester prodrugs of 2'-deoxy-4'-thioadenosine and its corresponding 9alpha anomer. Nucleosides, nucleotides & nucleic acids 20050101
Cdk inhibitory nucleoside analogs prevent transcription from viral genomes. Nucleosides, nucleotides & nucleic acids 20050101
7-deazapurin-2,6-diamine and 7-deazaguanine: synthesis and property of 7-substituted nucleosides and oligonucleotides. Nucleosides, nucleotides & nucleic acids 20050101
6-azapyrimidine and 7-deazapurine 2'-deoxy-2'-fluoroarabinonucleosides: synthesis, conformation and properties of oligonucleotides. Nucleosides, nucleotides & nucleic acids 20050101
Synthesis and biological activity of 2-fluoro adenine and 6-methyl purine nucleoside analogs as prodrugs for suicide gene therapy of cancer. Nucleosides, nucleotides & nucleic acids 20050101
Synthesis and biological activity of 2'-deoxy-4'-thio-pyrazolo[3,4-d]pyrimidine nucleosides. Nucleosides, nucleotides & nucleic acids 20050101
Synthesis and anti-hepatitis C virus activity of nucleoside derivatives of N3, 5'-anhydro-4-(beta-D-ribofuranosyl)-8-aza-purin-2-ones. Nucleosides, nucleotides & nucleic acids 20050101
Functionalization of pyrimidine and purine nucleosides at C4 and C6: C-nucleophilic substitution of their C4- and C6-(1,2,4-triazol-1-yl) derivatives. Nucleosides, nucleotides & nucleic acids 20050101
Stereoselective synthesis of novel thioiso dideoxy nucleosides with exocyclic methylene as potential antiviral agents. Nucleosides, nucleotides & nucleic acids 20050101
Chemistry and dynamics of interaction of nucleosides with pentafluoropyridine. Nucleosides, nucleotides & nucleic acids 20050101
Propofol attenuates oxidant-induced acute lung injury in an isolated perfused rabbit-lung model. Journal of anesthesia 20050101
Preclinical development of Alimta (Pemetrexed, LY231514), a multitargeted antifolate. Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20050101
The contact-mediated response of peripheral-blood monocytes to preactivated T cells is suppressed by serum factors in rheumatoid arthritis. Arthritis research & therapy 20050101
A computational investigation of kinetoplastid trans-splicing. Genome biology 20050101
Studies of the intermediary metabolism in cultured cells of the insect Spodoptera frugiperda using 13C- or 15N-labelled tracers. BMC biochemistry 20050101
Single and repeated moderate consumption of native or dealcoholized red wine show different effects on antioxidant parameters in blood and DNA strand breaks in peripheral leukocytes in healthy volunteers: a randomized controlled trial (ISRCTN68505294). Nutrition journal 20050101
Salvage therapy for CLL and the role of stem cell transplantation. Hematology. American Society of Hematology. Education Program 20050101
Transition states and inhibitors of the purine nucleoside phosphorylase family. Current topics in medicinal chemistry 20050101
PNP anticancer gene therapy. Current topics in medicinal chemistry 20050101
Purine derivatives as ligands for A3 adenosine receptors. Current topics in medicinal chemistry 20050101
Multiple phosphorylation events control mitotic degradation of the muscle transcription factor Myf5. BMC biochemistry 20050101
Biphasic effect of extracellular ATP on human and rat airways is due to multiple P2 purinoceptor activation. Respiratory research 20050101
A phase II study of fixed dose rate gemcitabine in patients with relapsed müllerian tumors. International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20050101
Therapy of chronic lymphocytic leukaemia with purine nucleoside analogues: facts and controversies. Drugs & aging 20050101
Overview of hyperuricaemia and gout. Current pharmaceutical design 20050101
Dietary factors and hyperuricaemia. Current pharmaceutical design 20050101
Uric acid and oxidative stress. Current pharmaceutical design 20050101
Oligomeric structure of mammalian purine nucleoside phosphorylase in solution determined by analytical ultracentrifugation. Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101
Inhibition of defective adenylosuccinate lyase by HNE: a neurological disease that may be affected by oxidative stress. BioFactors (Oxford, England) 20050101
Immunotherapeutic approaches in ocular inflammatory diseases. Archivum immunologiae et therapiae experimentalis 20050101
[Immunosuppressive drugs and renal transplantation]. Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20050101
Molecular processes during fat cell development revealed by gene expression profiling and functional annotation. Genome biology 20050101
Synthesis and anti-HIV activity of beta-D-3'-azido-2',3'-unsaturated nucleosides and beta-D-3'-azido-3'-deoxyribofuranosylnucleosides. Nucleosides, nucleotides & nucleic acids 20050101
Synthesis and pharmacokinetic and pharmacodynamic evaluation of the forodesine HCl analog BCX-3040. Nucleosides, nucleotides & nucleic acids 20050101
Synthesis and biological activity of 4'-thio-L-xylofuranosyl purine nucleosides. Nucleosides, nucleotides & nucleic acids 20050101
Pyrimidine and purine analogues, effects on cell cycle regulation and the role of cell cycle inhibitors to enhance their cytotoxicity. Nucleosides, nucleotides & nucleic acids 20050101
Integrative analysis of genome-wide experiments in the context of a large high-throughput data compendium. Molecular systems biology 20050101
Searching genomes for noncoding RNA using FastR. IEEE/ACM transactions on computational biology and bioinformatics 20050101
Novel modified purine bases and nucleosides: new methodologies of synthesis and biological activity. Nucleic acids symposium series (2004) 20050101
Biophysical and biochemical properties of oxanine-containing oligodeoxynucleotide. Nucleic acids symposium series (2004) 20050101
Synthesis of purin-2-yl carboxylate from O6-methylguanosine. Nucleic acids symposium series (2004) 20050101
Activity of nucleotide excision repair enzymes for oxanine cross-link lesions. Nucleic acids symposium series (2004) 20050101
Mycophenolate Mofetil (MMF) Efficacy in Glomerulonephritis (GN), a Retrospective Analysis. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20050101
Genetic barriers to resistance and impact on clinical response. Journal of the International AIDS Society 20050101
Exotic diseases of dogs and cats at risk of importation to Ireland. Irish veterinary journal 20050101
Synthesis and antitumor activity of methyltriazene prodrugs simultaneously releasing DNA-methylating agents and the antiresistance drug O(6)-benzylguanine. Journal of medicinal chemistry 20041230
Cocyclotrimerization of 6-alkynylpurines with alpha,omega-diynes as a novel approach to biologically active 6-arylpurines. The Journal of organic chemistry 20041224
Active site contacts in the purine nucleoside phosphorylase--hypoxanthine complex by NMR and ab initio calculations. Biochemistry 20041221
Synthesis of a biotin-conjugate of phosmidosine O-ethyl ester as a G1 arrest antitumor drug. Bioorganic & medicinal chemistry 20041215
Monitoring HSVtk suicide gene therapy: the role of [(18)F]FHPG membrane transport. British journal of cancer 20041213
Metabolic sensitivity of pancreatic tumour cell apoptosis to glycogen phosphorylase inhibitor treatment. British journal of cancer 20041213
Production of the carbonate radical anion during xanthine oxidase turnover in the presence of bicarbonate. The Journal of biological chemistry 20041210
Human deoxycytidine kinase as a deoxyribonucleoside phosphorylase. Journal of molecular biology 20041210
Isolation of fast purine nucleotide synthase ribozymes. Journal of the American Chemical Society 20041208
Promoting vibrations in human purine nucleoside phosphorylase. A molecular dynamics and hybrid quantum mechanical/molecular mechanical study. Journal of the American Chemical Society 20041208
Hyperbaric and normobaric reoxygenation of hypoxic rat brain slices--impact on purine nucleotides and cell viability. Neurochemistry international 20041201
Adenosine stimulation of proliferation of breast carcinoma cell lines: evaluation of the [3H]thymidine assay system and modulatory effects of the cellular microenvironment in vitro. Journal of cellular physiology 20041201
Glutathione-dependent reduction of arsenate in human erythrocytes--a process independent of purine nucleoside phosphorylase. Toxicological sciences : an official journal of the Society of Toxicology 20041201
Reduced-intensity conditioning using TBI (8 Gy), fludarabine, cyclophosphamide and ATG in elderly CML patients provides excellent results especially when performed in the early course of the disease. Bone marrow transplantation 20041201
Purine nucleoside phosphorylase and fludarabine phosphate gene-directed enzyme prodrug therapy suppresses primary tumour growth and pseudo-metastases in a mouse model of prostate cancer. The journal of gene medicine 20041201
The influence of farnesyl protein transferase inhibitor R115777 (Zarnestra) alone and in combination with purine nucleoside analogs on acute myeloid leukemia progenitors in vitro. European journal of haematology 20041201
Functional analysis of the murine Emr1 promoter identifies a novel purine-rich regulatory motif required for high-level gene expression in macrophages. Genomics 20041201
Structure of a purine-purine wobble base pair in the decoding center of the ribosome. Nature structural & molecular biology 20041201
Receptor regulatory properties evident in the molecular similarity of serotonin receptor ligands and purine nucleotides. The Journal of pharmacy and pharmacology 20041201
Mapping of the bovine genes of the de novo AMP synthesis pathway. Animal genetics 20041201
Pentostatin - pharmacology, immunology, and clinical effects in graft-versus-host disease. Expert opinion on pharmacotherapy 20041201
Autoinhibition of transmitter release from PC12 cells and sympathetic neurons through a P2Y receptor-mediated inhibition of voltage-gated Ca2+ channels. The European journal of neuroscience 20041201
MTHFR polymorphisms, diet, HRT, and breast cancer risk: the multiethnic cohort study. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041201
Structural basis for discriminative regulation of gene expression by adenine- and guanine-sensing mRNAs. Chemistry & biology 20041201
Drosophila melanogaster Prat, a purine de novo synthesis gene, has a pleiotropic maternal-effect phenotype. Genetics 20041201
Purine receptors: GPCR structure and agonist design. Molecular interventions 20041201
Immunomodulatory therapy for inflammatory bowel disease. Journal of gastroenterology 20041201
Transport of endogenous nucleosides in guinea pig heart. Canadian journal of physiology and pharmacology 20041201
The vascular endothelial growth factor-induced disruption of gap junctions is relayed by an autocrine communication via ATP release in coronary capillary endothelium. Annals of the New York Academy of Sciences 20041201
Does asymptomatic hyperuricaemia contribute to the development of renal and cardiovascular disease? An old controversy renewed. Nephrology (Carlton, Vic.) 20041201
Purine nucleotides and their metabolites in erythrocytes of streptozotocin diabetic rats. Diabetes & metabolism 20041201
[Composition of renal stones currently observed in non-industrialized countries]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20041201
P2Y receptors and pain transmission. Purinergic signalling 20041201
P2 receptors are involved in the mediation of motivation-related behavior. Purinergic signalling 20041201
Regulation of neuronal ion channels via P2Y receptors. Purinergic signalling 20041201
Coronary artery reperfusion: The ADP receptor P2Y(1) mediates early reactive hyperemia in vivo in pigs. Purinergic signalling 20041201
Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2. Circulation research 20041126
Pd-catalyzed amination of nucleoside arylsulfonates to yield N6-aryl-2,6-diaminopurine nucleosides. Angewandte Chemie (International ed. in English) 20041126
Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K. Journal of medicinal chemistry 20041118
Structure of a natural guanine-responsive riboswitch complexed with the metabolite hypoxanthine. Nature 20041118
Shift in purine/pyrimidine base recognition upon exchanging extracellular domains in P2Y 1/6 chimeric receptors. Biochemical pharmacology 20041115
Crystallographic structure of PNP from Mycobacterium tuberculosis at 1.9A resolution. Biochemical and biophysical research communications 20041112
A facile and efficient synthesis of (Purin-6-yl)alanines. The Journal of organic chemistry 20041112
Synthesis and degradation of nucleobases and nucleic acids by formamide in the presence of montmorillonites. Chembiochem : a European journal of chemical biology 20041105
Dynamics in the U6 RNA intramolecular stem-loop: a base flipping conformational change. Biochemistry 20041102
Vardenafil: structural basis for higher potency over sildenafil in inhibiting cGMP-specific phosphodiesterase-5 (PDE5). Neurochemistry international 20041101
Methylthioadenosine. The international journal of biochemistry & cell biology 20041101
Metabolic regulation of ATP breakdown and of adenosine production in rat brain extracts. The international journal of biochemistry & cell biology 20041101
Preclinical evaluation of a prostate-targeted gene-directed enzyme prodrug therapy delivered by ovine atadenovirus. Gene therapy 20041101
Broad specificity of human phosphoglycerate kinase for antiviral nucleoside analogs. Biochemical pharmacology 20041101
Membrane permeation characteristics of abacavir in human erythrocytes and human T-lymphoblastoid CD4+ CEM cells: comparison with (-)-carbovir. Biochemical pharmacology 20041101
Anabolism of amdoxovir: phosphorylation of dioxolane guanosine and its 5'-phosphates by mammalian phosphotransferases. Biochemical pharmacology 20041101
Nutritional requirements of Lactobacillus delbrueckii subsp. lactis in a chemically defined medium. Current microbiology 20041101
Simultaneous determination of multiple constituents in real beer samples of different origins by capillary zone electrophoresis. Analytical and bioanalytical chemistry 20041101
Axiom of determining transcription start points by RNA polymerase in Escherichia coli. Molecular microbiology 20041101
Protein thiol modifications visualized in vivo. PLoS biology 20041101
Unanticipated antigens: translation initiation at CUG with leucine. PLoS biology 20041101
A pilot trial of rituximab and alemtuzumab combination therapy in patients with relapsed and/or refractory chronic lymphocytic leukemia (CLL). Leukemia & lymphoma 20041101
[Synthesis of phosphonic acid and phosphinic acid derivatives for development of biologically active compounds]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20041101
Purine nucleoside phosphorylase deficiency (PNP-def) presenting with lymphopenia and developmental delay: successful correction with umbilical cord blood transplantation. The Journal of pediatrics 20041101
Coordination mode and oxidation susceptibility of nickel(II) complexes with 2'-deoxyguanosine 5'-monophosphate and l-histidine. Journal of inorganic biochemistry 20041101
Water-soluble platinum(II) complexes of diamine chelating ligands bearing amino-acid type substituents: the effect of the linked amino acid and the diamine chelate ring size on antitumor activity, and interactions with 5'-GMP and DNA. Journal of inorganic biochemistry 20041101
GMP and AMP as methyl radical traps in the reaction with pentaamminemethylcobalt(III). Journal of inorganic biochemistry 20041101
Determinants of selectivity in alkylation of nucleosides and DNA by secondary diazonium ions: evidence for, and consequences of, a preassociation mechanism. Chemical research in toxicology 20041101
Allelic isoforms of the H+/nucleoside co-transporter (CaCNT) from Candida albicans reveal separate high- and low-affinity transport systems for nucleosides. Yeast (Chichester, England) 20041101
Etched chemically modified capillaries: novel separation media for electrophoretic analyses. Journal of separation science 20041101
Current management of gout in patients unresponsive or allergic to allopurinol. Joint, bone, spine : revue du rhumatisme 20041101
Prediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast cell lines. Environmental health perspectives 20041101
[Purine nucleoside phosphorylase (PNP)]. Nihon rinsho. Japanese journal of clinical medicine 20041101
Translational research with pemetrexed in breast cancer. Oncology (Williston Park, N.Y.) 20041101
Bias explorer: measurements of compositional bias in EMBL and GenBank sequence files. Antonie van Leeuwenhoek 20041101
The influence of chemotherapy on bone marrow in patients with chronic lymphocytic leukaemia. Folia morphologica 20041101
[Raman spectroscopic study on the influence of ultraviolet radiation on calf thymus DNA in aqueous solution]. Guang pu xue yu guang pu fen xi = Guang pu 20041101
Role of interstitial ATP and adenosine in the regulation of renal hemodynamics and microvascular function. Hypertension research : official journal of the Japanese Society of Hypertension 20041101
Nitrogen oxide blockade does not aggravate the endothelin-1-induced myocardial ischemia and release of purine metabolites from the dog heart. Journal of cardiovascular pharmacology 20041101
Exploratory studies to investigate a linked prebiotic origin of RNA and coded peptides. 3rd communication. Behaviour of 5-amino-1H-imidazole-4-carbonitrile derivatives. Chemistry & biodiversity 20041101
Differential gene expression profiles of radioresistant oesophageal cancer cell lines established by continuous fractionated irradiation. British journal of cancer 20041018
Crystallographic structure of the nuclease domain of 3'hExo, a DEDDh family member, bound to rAMP. Journal of molecular biology 20041015
Gas-phase acidity studies of multiple sites of adenine and adenine derivatives. The Journal of organic chemistry 20041015
Factors affecting thermodynamic stabilities of RNA 3 x 3 internal loops. Biochemistry 20041012
Acid-base properties of xanthosine 5'-monophosphate (XMP) and of some related nucleobase derivatives in aqueous solution: micro acidity constant evaluations of the (N1)H versus the (N3)H deprotonation ambiguity. Chemistry (Weinheim an der Bergstrasse, Germany) 20041011
Specific and non-specific purine trap in the T-loop of normal and suppressor tRNAs. Journal of molecular biology 20041008
Halogenated 7-deazapurine nucleosides: stereoselective synthesis and conformation of 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides. Organic & biomolecular chemistry 20041007
Structure-activity relationship of heterobase-modified 2'-C-methyl ribonucleosides as inhibitors of hepatitis C virus RNA replication. Journal of medicinal chemistry 20041007
Involvement of adenosine A1 receptors in upregulation of nitric oxide by acyclic nucleotide analogues. European journal of pharmacology 20041006
Binding of DNA purine sites to dirhodium compounds probed by mass spectrometry. Inorganic chemistry 20041004
Characterization of three novel members of the Arabidopsis thaliana equilibrative nucleoside transporter (ENT) family. The Biochemical journal 20041001
DUK114, the Drosophila orthologue of bovine brain calpain activator protein, is a molecular chaperone. The Biochemical journal 20041001
Investigation on the causes of codon and amino acid usages variation between thermophilic Aquifex aeolicus and mesophilic Bacillus subtilis. Journal of biomolecular structure & dynamics 20041001
Conformational analysis of canonical 2-deoxyribonucleotides. 2. Purine nucleotides. Journal of biomolecular structure & dynamics 20041001
Measurement of DNA adducts in cells exposed to cisplatin. Analytical biochemistry 20041001
New nucleoside reverse transcriptase inhibitors for the treatment of HIV infections. Current opinion in pharmacology 20041001
Structure-activity relationship of phosmidosine: importance of the 7,8-dihydro-8-oxoadenosine residue for antitumor activity. Bioorganic & medicinal chemistry 20041001
The influence of DNA stiffness upon nucleosome formation. Journal of structural biology 20041001
Inter-domain motions of the N-domain of the KdpFABC complex, a P-type ATPase, are not driven by ATP-induced conformational changes. Journal of molecular biology 20041001
Acute myeloid leukemia following treatment with cladribine for hairy cell leukemia: a case report and review of the literature. Leukemia & lymphoma 20041001
Kupffer cell depletion attenuates superoxide anion release into the hepatic sinusoids after lipopolysaccharide treatment. Journal of gastroenterology and hepatology 20041001
Reducing concentrate supplementation in dairy cow diets while maintaining milk production with pea-wheat intercrops. Journal of dairy science 20041001
Characterization of pco-1, a newly identified gene which regulates purine catabolism in Neurospora. Current genetics 20041001
A comprehensive proteome map of growing Bacillus subtilis cells. Proteomics 20041001
Identification and characterization of a novel gene of grouper iridovirus encoding a purine nucleoside phosphorylase. The Journal of general virology 20041001
Proteomic basis for the possible use of lymphocytes for metabolic screenings. Amino acids 20041001
Comparison of structural effects in 1,4 DNA-DNA interstrand cross-links formed by dinuclear and trinuclear platinum complexes. Journal of inorganic biochemistry 20041001
Ecto-5'-nucleotidase activity in brain membranes of zebrafish (Danio rerio). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20041001
The effect of folic acid and folinic acid supplements on purine metabolism in methotrexate-treated rheumatoid arthritis. Arthritis and rheumatism 20041001
Ruminal fermentation and degradation patterns, protozoa population and urinary purine derivatives excretion in goats and wethers fed diets based on olive leaves. Journal of animal science 20041001
Development of ectopic roots from abortive nodule primordia. Molecular plant-microbe interactions : MPMI 20041001
Identification of Leishmania strains from Jordan. Annals of tropical medicine and parasitology 20041001
Purine nucleoside phosphorylase activity in rat cerebrospinal fluid. Neurochemical research 20041001
Redox state of endogenous coenzyme q modulates the inhibition of linoleic acid-induced uncoupling by guanosine triphosphate in isolated skeletal muscle mitochondria. Journal of bioenergetics and biomembranes 20041001
Exogenous nucleosides are required for the morphogenesis of the human filarial parasite Brugia malayi. The Journal of parasitology 20041001
Purine and pyrimidine metabolism: new challenges. Nucleosides, nucleotides & nucleic acids 20041001
Purine modulation of cytokine release during diuretic therapy of rheumatoid arthritis. Nucleosides, nucleotides & nucleic acids 20041001
Clinical and biochemical manifestations and molecular characterization of the mutation HPRT Jerusalem. Nucleosides, nucleotides & nucleic acids 20041001
Nucleotide degradation products in cerebrospinal fluid (CSF) in inherited and acquired pathologies. Nucleosides, nucleotides & nucleic acids 20041001
Severe impairment of nucleotide synthesis through inhibition of mitochondrial respiration. Nucleosides, nucleotides & nucleic acids 20041001
Liver transplant: adenosine metabolism and apoptosis. Nucleosides, nucleotides & nucleic acids 20041001
Immucillins as antibiotics for T-cell proliferation and malaria. Nucleosides, nucleotides & nucleic acids 20041001
Novel mutations and hot-spots in patients with purine nucleoside phosphorylase deficiency. Nucleosides, nucleotides & nucleic acids 20041001
Selective transport of a new class of purine antimetabolites by the protozoan parasite Trypanosoma brucei. Nucleosides, nucleotides & nucleic acids 20041001
Metabolism of adenosine in human colorectal tumour. Nucleosides, nucleotides & nucleic acids 20041001
Human DNA primase uses Watson-Crick hydrogen bonds to distinguish between correct and incorrect nucleoside triphosphates. Biochemistry 20040928
Enhancing Hoogsteen interactions: a pyrrole-containing purine nucleoside that competes with guanosine self-assembly. Journal of the American Chemical Society 20040922
Stability of RNA hairpin loops closed by AU base pairs. Biochemistry 20040921
Human UP1 as a model for understanding purine recognition in the family of proteins containing the RNA recognition motif (RRM). Journal of molecular biology 20040917
Crystal structure of calf spleen purine nucleoside phosphorylase with two full trimers in the asymmetric unit: important implications for the mechanism of catalysis. Journal of molecular biology 20040917
Azoles as Suzuki cross-coupling leaving groups: syntheses of 6-arylpurine 2'-deoxynucleosides and nucleosides from 6-(imidazol-1-yl)- and 6-(1,2,4-triazol-4-yl)purine derivatives. Organic letters 20040916
Voltammetric determination of all DNA nucleotides. Analytical biochemistry 20040915
Comprehensive analysis of the 9p21 region in neuroblastoma suggests a role for genes mapping to 9p21-23 in the biology of favourable stage 4 tumours. British journal of cancer 20040913
A novel 1p36.2 located gene, APITD1, with tumour-suppressive properties and a putative p53-binding domain, shows low expression in neuroblastoma tumours. British journal of cancer 20040913
Native UCP1 displays simple competitive kinetics between the regulators purine nucleotides and fatty acids. The Journal of biological chemistry 20040910
Oxanine DNA glycosylase activity from Mammalian alkyladenine glycosylase. The Journal of biological chemistry 20040910
Structural bioinformatics study of PNP from Schistosoma mansoni. Biochemical and biophysical research communications 20040910
Design, synthesis, and biological evaluation of 1,2,3,7-tetrahydro-6h-purin-6-one and 3,7-dihydro-1h-purine-2,6-dione derivatives as corticotropin-releasing factor(1) receptor antagonists. Journal of medicinal chemistry 20040909
One-dimensional oxalato-bridged Cu(II), Co(II), and Zn(II) complexes with purine and adenine as terminal ligands. Inorganic chemistry 20040906
The expression of mitochondrial methylenetetrahydrofolate dehydrogenase-cyclohydrolase supports a role in rapid cell growth. Biochimica et biophysica acta 20040906
The purine transferase from Trypanosoma cruzi as a potential target for bisphosphonate-based chemotherapeutic compounds. Bioorganic & medicinal chemistry letters 20040906
Synthesis of 3'-fluoro-2',3'-dideoxy-2',3'-didehydro-4'-ethynyl-D- and -L-furanosyl nucleosides. The Journal of organic chemistry 20040903
Acute lymphoblastic leukemia with TEL-AML1 fusion has lower expression of genes involved in purine metabolism and lower de novo purine synthesis. Blood 20040901
Quantitative analysis of liver protein expression during hibernation in the golden-mantled ground squirrel. Molecular & cellular proteomics : MCP 20040901
Activation of P2 nucleotide receptors stimulates acid efflux from astrocytes. Glia 20040901
Resistance to purine and pyrimidine nucleoside and nucleobase analogs by the human MDR1 transfected murine leukemia cell line L1210/VMDRC.06. Biochemical pharmacology 20040901
Identification of the P2Y(12) receptor in nucleotide inhibition of exocytosis from bovine chromaffin cells. Molecular pharmacology 20040901
Cutaneous adverse reaction to 2-chlorodeoxyadenosine with histological flame figures in patients with chronic lymphocytic leukaemia. Journal of the European Academy of Dermatology and Venereology : JEADV 20040901
The role of fludarabine in the treatment of follicular and mantle cell lymphoma. Cancer 20040901
6-(4-Methoxybenzylamino)purin-3-ium chloride. Acta crystallographica. Section C, Crystal structure communications 20040901
Effect of molasses supplementation on the production of lactating dairy cows fed diets based on alfalfa and corn silage. Journal of dairy science 20040901
Effect of lead ions on rat erythrocyte purine content. Biological trace element research 20040901
Effect of testosterone on purine nucleotide metabolism in rat liver. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040901
Disturbances of purine nucleotide metabolism in uremia. Seminars in nephrology 20040901
[Physiology and biochemistry of uric acid]. Therapeutische Umschau. Revue therapeutique 20040901
Gene therapy for adenosine-deaminase-deficient severe combined immunodeficiency. Best practice & research. Clinical haematology 20040901
Sequence features of Oxytricha trifallax (class Spirotrichea) macronuclear telomeric and subtelomeric sequences. Protist 20040901
[New perspectives in the evolution of prognosis and treatment of chronic lymphocytic leukaemia]. Orvosi hetilap 20040829
Improved antiviral activity of the aryloxymethoxyalaninyl phosphoramidate (APA) prodrug of abacavir (ABC) is due to the formation of markedly increased carbovir 5'-triphosphate metabolite levels. FEBS letters 20040827
Mercaptoheterocyclic ligands grafted on a poly(ethylene vinyl alcohol) membrane for the purification of immunoglobulin G in a salt independent thiophilic chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040825
Conformationally constrained purine mimics. Incorporation of adenine and guanine into spirocyclic nucleosides. The Journal of organic chemistry 20040820
SNAr iodination of 6-chloropurine nucleosides: aromatic Finkelstein reactions at temperatures below -40 degrees C. Organic letters 20040819
Domain organization of Salmonella typhimurium formylglycinamide ribonucleotide amidotransferase revealed by X-ray crystallography. Biochemistry 20040817
A model for the Bacillus subtilis formylglycinamide ribonucleotide amidotransferase multiprotein complex. Biochemistry 20040817
Activating the phosphate nucleophile at the catalytic site of purine nucleoside phosphorylase: a vibrational spectroscopic study. Journal of the American Chemical Society 20040811
Spermine participates in oxidative damage of guanosine and 8-oxoguanosine leading to deoxyribosylurea formation. Journal of the American Chemical Society 20040811
Structural and energetic consequences of expanding a highly cooperative stable DNA hairpin loop. Journal of the American Chemical Society 20040811
Stacking-unstacking dynamics of oligodeoxynucleotide trimers. Biochemistry 20040810
Structure of human MTH1, a Nudix family hydrolase that selectively degrades oxidized purine nucleoside triphosphates. The Journal of biological chemistry 20040806
Exploring Hoogsteen and reversed-Hoogsteen duplex and triplex formation with tricyclo-DNA purine sequences. Chembiochem : a European journal of chemical biology 20040806
Epitaxial relationships between uric acid crystals and mineral surfaces: a factor in urinary stone formation. Langmuir : the ACS journal of surfaces and colloids 20040803
Partial B-to-A DNA transition upon minor groove binding of protein Sac7d monitored by Raman spectroscopy. Biochemistry 20040803
In vitro assessment of nucleoside analogs in multiple myeloma. Cancer chemotherapy and pharmacology 20040801
Treatment of T-cell non-Hodgkin's lymphoma. Current treatment options in oncology 20040801
Characterization of purine receptors in mouse thoracic aorta. Journal of cardiovascular pharmacology 20040801
A reassessment of the response of the bacterial ribosome to the frameshift stimulatory signal of the human immunodeficiency virus type 1. RNA (New York, N.Y.) 20040801
Neuronal A1 receptors mediate increase in extracellular kynurenic acid after local intrastriatal adenosine infusion. Journal of neurochemistry 20040801
Exclusion of galectin 9 as a candidate gene for hyperuricosuria in the Dalmatian dog. Animal genetics 20040801
Coordination mode of adenosine 5'-diphosphate in ternary systems containing Cu(II), Cd(II) or Hg(II) ions and polyamines. Journal of inorganic biochemistry 20040801
Calf spleen purine-nucleoside phosphorylase: crystal structure of the binary complex with a potent multisubstrate analogue inhibitor. Acta crystallographica. Section D, Biological crystallography 20040801
Global changes in transcription orchestrate metabolic differentiation during symbiotic nitrogen fixation in Lotus japonicus. The Plant journal : for cell and molecular biology 20040801
Proteomic response to amino acid starvation in Candida albicans and Saccharomyces cerevisiae. Proteomics 20040801
Early central nervous system complications after reduced-intensity stem cell transplantation. Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040801
Structure of Escherichia coli AMP nucleosidase reveals similarity to nucleoside phosphorylases. Structure (London, England : 1993) 20040801
Maternal plasma hypoxanthine levels in nonpreeclamptic twin pregnancies. The Tohoku journal of experimental medicine 20040801
Interaction between intrathecal gabapentin and adenosine in the formalin test of rats. Journal of Korean medical science 20040801
3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone, forms DNA adducts after metabolic activation by human and rat liver microsomes: evidence for activation by cytochrome P450 1A1 and P450 1A2. Chemical research in toxicology 20040801
The regenerative plasticity of isolated urodele myofibers and its dependence on MSX1. PLoS biology 20040801
Unraveling the molecular basis for regenerative cellular plasticity. PLoS biology 20040801
Human sebaceous glands engage in aerobic glycolysis and glutaminolysis. The British journal of dermatology 20040801
Role of low-dose 2-CdA in refractory or resistant lymphoplasmocytic lymphoma. Journal of chemotherapy (Florence, Italy) 20040801
Urinary excretion of purine derivatives as an index of microbial protein synthesis in the camel (Camelus dromedarius). The British journal of nutrition 20040801
[Study on beverages and kidney stone disease]. Hinyokika kiyo. Acta urologica Japonica 20040801
A novel purine nucleoside transporter whose expression is up-regulated in the short stumpy form of the Trypanosoma brucei life cycle. Molecular and biochemical parasitology 20040801
Enzymatic transesterification of purine nucleoside having a low solubility in organic medium. Biotechnology letters 20040801
Genomic-scale analysis of bacterial gene and protein expression in the host. Emerging infectious diseases 20040801
Effect of insulin on spontaneous and progesterone-induced GVBD on Bufo arenarum denuded oocytes. Zygote (Cambridge, England) 20040801
Identification of protein coding regions of rice genes using alternative spectral rotation measure and linear discriminant analysis. Genomics, proteomics & bioinformatics 20040801
Purine salvage pathways in the apicomplexan parasite Toxoplasma gondii. The Journal of biological chemistry 20040723
A glutamine switch mechanism for nucleotide selectivity by phosphodiesterases. Molecular cell 20040723
Changes in purine levels and adenosine receptors in kindled seizures in the rat. Neuroreport 20040719
Two metal ions coordinated to a purine residue tolerate each other well. Angewandte Chemie (International ed. in English) 20040719
QSAR of adenosine receptor antagonists. Part 3: Exploring physicochemical requirements for selective binding of 1,2,4-triazolo[5,1-i]purine derivatives with human adenosine A3 receptor subtype. Bioorganic & medicinal chemistry letters 20040716
Adenosine acts through A2 receptors to inhibit IL-2-induced tyrosine phosphorylation of STAT5 in T lymphocytes: role of cyclic adenosine 3',5'-monophosphate and phosphatases. Journal of immunology (Baltimore, Md. : 1950) 20040715
A nucleic acid biosensor for gene expression analysis in nanograms of mRNA. Analytical chemistry 20040715
The nucleoside derivative 5'-O-trityl-inosine (KIN59) suppresses thymidine phosphorylase-triggered angiogenesis via a noncompetitive mechanism of action. The Journal of biological chemistry 20040709
Structural and kinetic analyses of the interaction of anthrax adenylyl cyclase toxin with reaction products cAMP and pyrophosphate. The Journal of biological chemistry 20040709
Adenosine uptake inhibitors. European journal of pharmacology 20040708
Conformational properties of shape modified nucleosides--fleximers. Journal of the American Chemical Society 20040707
Kinetic and thermodynamic analysis of the hydrolytic ring-opening of the malondialdehyde-deoxyguanosine adduct, 3-(2'-deoxy-beta-D-erythro-pentofuranosyl)- pyrimido[1,2-alpha]purin-10(3H)-one. Journal of the American Chemical Society 20040707
Esterase activity as a novel parameter of spore germination in Bacillus anthracis. Biochemical and biophysical research communications 20040702
Mycophenolate mofetil treatment following renal transplantation decreases GTP concentrations in mononuclear leucocytes. Clinical science (London, England : 1979) 20040701
Medical approaches and future options in chronic active ulcerative colitis. International journal of colorectal disease 20040701
P2Y purine receptor responses and expression in the pulmonary circulation of juvenile rabbits. American journal of physiology. Heart and circulatory physiology 20040701
Molecular and functional aspects of human cysteinyl leukotriene receptors. Pharmacological research 20040701
Antiproliferative activity of a triplex-forming oligonucleotide recognizing a Ki-ras polypurine/polypyrimidine motif correlates with protein binding. Cancer gene therapy 20040701
Trichomonas vaginalis: cytochemical localization of a NTPDase1 and an ecto-5'-nucleotidase and effects of adenine nucleotides on cellular viability. Parasitology research 20040701
A non-active site mutation in human hypoxanthine guanine phosphoribosyltransferase expands substrate specificity. Archives of biochemistry and biophysics 20040701
The clinical and epidemiological burden of chronic lymphocytic leukaemia. European journal of cancer care 20040701
Metabolic risk factors and the impact of medical therapy on the management of nephrolithiasis in obese patients. The Journal of urology 20040701
Oxaliplatin/rituximab combination in the treatment of intermediate-low grade non-Hodgkin's lymphoma of elderly patients. Oncology reports 20040701
Steady-state kinetics of the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi. Biochimica et biophysica acta 20040701
Treatment with the purine synthesis inhibitor mizoribine for ANCA-associated renal vasculitis. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040701
Towards the pharmacotherapy of hairy cell leukaemia. Expert opinion on pharmacotherapy 20040701
Adenosine down-regulates the surface expression of dipeptidyl peptidase IV on HT-29 human colorectal carcinoma cells: implications for cancer cell behavior. The American journal of pathology 20040701
Mining the proteome. Nature 20040701
Advances in chemotherapy for chronic lymphocytic leukemia. Seminars in hematology 20040701
A new vector, based on the PolII promoter of the U1 snRNA gene, for the expression of siRNAs in mammalian cells. Molecular therapy : the journal of the American Society of Gene Therapy 20040701
[Hairy cell leukemia therapy by cladribine]. Nihon rinsho. Japanese journal of clinical medicine 20040701
Ruminal fermentation and degradation patterns, protozoa population, and urinary purine derivatives excretion in goats and wethers fed diets based on two-stage olive cake: effect of PEG supply. Journal of animal science 20040701
A comparison of purine derivatives excretion with conventional methods as indices of microbial yield in dairy cows. Journal of dairy science 20040701
[Cladribine monotherapy for patients with relapsed or refractory indolent non-Hodgkin lymphoma]. [Rinsho ketsueki] The Japanese journal of clinical hematology 20040701
Altered circadian relationship between serum nitric oxide, carbon dioxide, and uric acid in multiple sclerosis. Chronobiology international 20040701
Medical therapy of Crohn disease. Current opinion in gastroenterology 20040701
The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site. The Journal of biological chemistry 20040625
Controlled transcriptional regulation in eukaryotes by a novel transcription factor derived from Escherichia coli purine repressor. Biochemical and biophysical research communications 20040625
Structure-based design, synthesis, and antimicrobial activity of purine derived SAH/MTA nucleosidase inhibitors. Bioorganic & medicinal chemistry letters 20040621
Synthesis and in vitro antimicrobial activities of 2-hydroxy-6-methyl-7-(arylamino)-1,7-dihydropurin-8-ones. Bioorganic & medicinal chemistry 20040615
Synthesis and antiproliferative activity of 2,6-diamino-9-benzyl-9-deazapurine and related compounds. Bioorganic & medicinal chemistry 20040615
Correlation of an adenine-specific conformational change with the ATP-dependent peptidase activity of Escherichia coli Lon. Biochemistry 20040615
Biosynthesis of tetrahydrofolate in plants: crystal structure of 7,8-dihydroneopterin aldolase from Arabidopsis thaliana reveals a novel adolase class. Journal of molecular biology 20040611
Binding causes the remote [5'-3H]thymidine kinetic isotope effect in human thymidine phosphorylase. Journal of the American Chemical Society 20040609
Identification of purine inhibitors of phosphodiesterase 7 (PDE7). Bioorganic & medicinal chemistry letters 20040607
Stm1p, a G4 quadruplex and purine motif triplex nucleic acid-binding protein, interacts with ribosomes and subtelomeric Y' DNA in Saccharomyces cerevisiae. The Journal of biological chemistry 20040604
Targeting the polyamine pathway with transition-state analogue inhibitors of 5'-methylthioadenosine phosphorylase. Journal of medicinal chemistry 20040603
High incidence of complications after 2-chloro-2'-deoxyadenosine combined with cyclophosphamide in patients with advanced lymphoproliferative malignancies. Annals of hematology 20040601
Purine and pyrimidine metabolism and electrocortical brain activity during hypoxemia in near-term lambs. Pediatric research 20040601
Microanalysis of DNA by stripping transfer voltammetry. Bioelectrochemistry (Amsterdam, Netherlands) 20040601
AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC. American journal of human genetics 20040601
Waldenström macroglobulinemia. Current treatment options in oncology 20040601
Cloning, expression, and purification of 5,10-methenyltetrahydrofolate synthetase from Mus musculus. Protein expression and purification 20040601
Purinergic signalling in the lung: important in asthma and COPD? Current opinion in pharmacology 20040601
Multiple functions for the invariant AGC triad of U6 snRNA. RNA (New York, N.Y.) 20040601
Plasma purine nucleoside phosphorylase in cancer patients. Clinica chimica acta; international journal of clinical chemistry 20040601
Binding of the potential antitumour agent indirubin-5-sulphonate at the inhibitor site of rabbit muscle glycogen phosphorylase b. Comparison with ligand binding to pCDK2-cyclin A complex. European journal of biochemistry 20040601
Saturation mutagenesis, complement selection, and steady-state kinetic studies illuminate the roles of invariant residues in active site loop I of the hypoxanthine phosphoribosyltransferase from Trypanosoma cruzi. Biochimica et biophysica acta 20040601
Effect of sauna bathing and beer ingestion on plasma concentrations of purine bases. Metabolism: clinical and experimental 20040601
Pharmacokinetics of 6-mercaptopurine in patients with inflammatory bowel disease: implications for therapy. Therapeutic drug monitoring 20040601
In silico prediction models for blood-brain barrier permeation. Current medicinal chemistry 20040601
Formation of 'non-culturable' cells of Mycobacterium smegmatis in stationary phase in response to growth under suboptimal conditions and their Rpf-mediated resuscitation. Microbiology (Reading, England) 20040601
Case report: the Lesch-Nyhan syndrome. European journal of paediatric dentistry : official journal of European Academy of Paediatric Dentistry 20040601
[Disorder of purine metabolism]. Nihon rinsho. Japanese journal of clinical medicine 20040601
Direct multicomponent analysis of beer samples constituents using micellar electrokinetic capillary chromatography. Electrophoresis 20040601
Purine nucleoside antimetabolites in development for the treatment of cancer. Current opinion in investigational drugs (London, England : 2000) 20040601
[Purine metabolism in patients with renal failure]. Nihon rinsho. Japanese journal of clinical medicine 20040601
[Xanthinuria with xanthine lithiasis in a patient with Lesch-Nyhan syndrome under allopurinol therapy]. Aktuelle Urologie 20040601
Physiology of folate and vitamin B12 in health and disease. Nutrition reviews 20040601
Distinctive expression of Myf5 in relation to differentiation and plasticity of newt muscle cells. The International journal of developmental biology 20040601
A novel class of phosphonate nucleosides. 9-[(1-phosphonomethoxycyclopropyl)methyl]guanine as a potent and selective anti-HBV agent. Journal of medicinal chemistry 20040520
HPLC-MSn analysis of phenolic compounds and purine alkaloids in green and black tea. Journal of agricultural and food chemistry 20040519
Structural comparison of MTA phosphorylase and MTA/AdoHcy nucleosidase explains substrate preferences and identifies regions exploitable for inhibitor design. Biochemistry 20040511
Sequence-dependent thermodynamic parameters for locked nucleic acid (LNA)-DNA duplex formation. Biochemistry 20040511
Differential inhibition of adenylyl cyclase isoforms and soluble guanylyl cyclase by purine and pyrimidine nucleotides. The Journal of biological chemistry 20040507
Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors. Life sciences 20040507
Ureide biosynthesis in legume nodules. Frontiers in bioscience : a journal and virtual library 20040501
Purine and pyrimidine nucleotide synthesis and degradation during in vitro morphogenesis of white spruce (Picea glauca). Frontiers in bioscience : a journal and virtual library 20040501
Applying high throughput techniques in the study of adenosine kinase in plant metabolism and development. Frontiers in bioscience : a journal and virtual library 20040501
Molecular analysis of 'de novo' purine biosynthesis in solanaceous species and in Arabidopsis thaliana. Frontiers in bioscience : a journal and virtual library 20040501
Caffeine synthase and related methyltransferases in plants. Frontiers in bioscience : a journal and virtual library 20040501
Distribution and biosynthesis of caffeine in plants. Frontiers in bioscience : a journal and virtual library 20040501
Reduced-intensity stem cell transplantation from an HLA-identical sibling donor in patients with myeloid malignancies. Bone marrow transplantation 20040501
Endotoxin challenge increases xanthine oxidase activity in cattle: effect of growth hormone and vitamin E treatment. Domestic animal endocrinology 20040501
Purine nucleoside analogues and combination therapies in B-cell chronic lymphocytic leukemia: dawn of a new era. Leukemia research 20040501
The antiapoptotic effect of guanosine is mediated by the activation of the PI 3-kinase/AKT/PKB pathway in cultured rat astrocytes. Glia 20040501
Determinants of plant U12-dependent intron splicing efficiency. The Plant cell 20040501
Dipyridamole protects the liver against warm ischemia and reperfusion injury. Journal of the American College of Surgeons 20040501
Potential role for the sorbitol pathway in the meiotic dysfunction exhibited by oocytes from diabetic mice. Journal of experimental zoology. Part A, Comparative experimental biology 20040501
Cleavage reactions of the complex ions derived from self-complementary deoxydinucleotides and alkali-metal ions using positive ion electrospray ionization with tandem mass spectrometry. Journal of the American Society for Mass Spectrometry 20040501
Endogenous adenosine modulates epileptiform activity in rat hippocampus in a receptor subtype-dependent manner. The European journal of neuroscience 20040501
Crystal structure to 1.7 a of the Escherichia coli pyrimidine nucleoside hydrolase YeiK, a novel candidate for cancer gene therapy. Structure (London, England : 1993) 20040501
Product analyses of ozone mediated nitration of benzimidazole derivatives with nitrogen dioxide: formation of 1-nitrobenzimidazoles and conversion to benzotriazoles. Chemical & pharmaceutical bulletin 20040501
Studies on the mechanism of action of xanthine oxidase. Journal of inorganic biochemistry 20040501
Synthesis and X-ray study of the 6-(N-pyrrolyl)purine and thymine derivatives of 1-aminocyclopropane-1-carboxylic acid. The journal of peptide research : official journal of the American Peptide Society 20040501
Medical therapy for ulcerative colitis 2004. Gastroenterology 20040501
Plastid sequence evolution: a new pattern of nucleotide substitutions in the Cucurbitaceae. Journal of molecular evolution 20040501
Treatment of indolent non-Hodgkin's lymphoma with cladribine as single-agent therapy and in combination with mitoxantrone. International journal of hematology 20040501
Physiological roles of xanthine oxidoreductase. Drug metabolism reviews 20040501
The potential of gene transfer into primary B-CLL cells using recombinant virus vectors. Leukemia & lymphoma 20040501
Epstein-Barr virus positive large B-cell lymphoma arising in a patient previously treated with Cladribine for hairy cell leukemia. Leukemia & lymphoma 20040501
The defense mechanisms in mammalian cells against oxidative damage in nucleic acids and their involvement in the suppression of mutagenesis and cell death. Free radical research 20040501
Antiviral therapy: nucleotide and nucleoside analogs. Clinics in liver disease 20040501
Purine and pyrimidine metabolism, designed by Donald Nicholson: Commentary. Biochemistry and molecular biology education : a bimonthly publication of the International Union of Biochemistry and Molecular Biology 20040501
Redox studies of subunit interactivity in aerobic ribonucleotide reductase from Escherichia coli. The Journal of biological chemistry 20040430
Plasmodium falciparum purine nucleoside phosphorylase: crystal structures, immucillin inhibitors, and dual catalytic function. The Journal of biological chemistry 20040430
Asymmetric synthesis of novel thioiso dideoxynucleosides with exocyclic methylene as potential antiviral agents. The Journal of organic chemistry 20040430
Efficient synthesis of an adenosine A2a agonist: glycosylation of 2-haloadenines and an N2-alkyl-6-chloroguanine. The Journal of organic chemistry 20040430
Crystal structures of human bifunctional enzyme aminoimidazole-4-carboxamide ribonucleotide transformylase/IMP cyclohydrolase in complex with potent sulfonyl-containing antifolates. The Journal of biological chemistry 20040423
An unsubstituted C2 hydrogen of adenine is critical and sufficient at the -11 position of a promoter to signal base pair deformation. The Journal of biological chemistry 20040423
Structure-activity relationship of purine ribonucleosides for inhibition of hepatitis C virus RNA-dependent RNA polymerase. Journal of medicinal chemistry 20040422
Escherichia coli mRNAs with strong Shine/Dalgarno sequences also contain 5' end sequences complementary to domain # 17 on the 16S ribosomal RNA. Biochemical and biophysical research communications 20040416
Leaving group activation by aromatic stacking: an alternative to general acid catalysis. Journal of molecular biology 20040416
Sequence and pH effects of LNA-containing triple helix-forming oligonucleotides: physical chemistry, biochemistry, and modeling studies. Biochemistry 20040413
Crystal structure of purine nucleoside phosphorylase from Thermus thermophilus. Journal of molecular biology 20040409
Synthesis, biological activity and molecular modeling of 6-benzylthioinosine analogues as subversive substrates of Toxoplasma gondii adenosine kinase. Journal of medicinal chemistry 20040408
Tandem orientation of duplicated xanthine dehydrogenase genes from Arabidopsis thaliana: differential gene expression and enzyme activities. The Journal of biological chemistry 20040402
Differential specificity of human and Escherichia coli endonuclease III and VIII homologues for oxidative base lesions. The Journal of biological chemistry 20040402
Inosine stimulates chemotaxis, Ca2+-transients and actin polymerization in immature human dendritic cells via a pertussis toxin-sensitive mechanism independent of adenosine receptors. Journal of cellular physiology 20040401
Xanthine dehydrogenase and aldehyde oxidase impact plant hormone homeostasis and affect fruit size in 'Hass' avocado. Journal of plant research 20040401
Biophysical characterization and molecular modeling of the coordinative-intercalative DNA monoadduct of a platinum-acridinylthiourea agent in a site-specifically modified dodecamer. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20040401
Proteomic determination of metabolic enzymes of the amnion cell: basis for a possible diagnostic tool? Proteomics 20040401
Transcription of purine transporter genes is activated during the isotropic growth phase of Aspergillus nidulans conidia. Molecular microbiology 20040401
Electrochemical coding of single-nucleotide polymorphisms by monobase-modified gold nanoparticles. Analytical chemistry 20040401
Mutagenicities of 8-hydroxyguanine and 2-hydroxyadenine produced by reactive oxygen species. Biological & pharmaceutical bulletin 20040401
Human DNA glycosylases involved in the repair of oxidatively damaged DNA. Biological & pharmaceutical bulletin 20040401
A novel missense mutation, c.584A > C (Y195S), in two unrelated Argentine patients with hypoxanthine-guanine phosphoribosyl-transferase deficiency, neurological variant. Molecular genetics and metabolism 20040401
Occurrence of a myelodysplastic syndrome (MDS) during first-line 2-chloro-deoxyadenosine (2-CDA) treatment of a low-grade gastrointestinal MALT lymphoma. Case report and review of the literature. Haematologica 20040401
Aspergillus fumigatus: a rare cause of vertebral osteomyelitis. Haematologica 20040401
Pneumocystis carinii pneumonia in chronic lymphocytic leukaemia. Postgraduate medical journal 20040401
The risk of cytomegalovirus infection in non-myeloablative peripheral stem cell transplantation compared with conventional bone marrow transplantation. Journal of Korean medical science 20040401
The C677 mutation in methylene tetrahydrofolate reductase gene: correlation with uric acid and cardiovascular risk factors in elderly Korean men. Journal of Korean medical science 20040401
Cofactor mimics as selective inhibitors of NAD-dependent inosine monophosphate dehydrogenase (IMPDH)--the major therapeutic target. Current medicinal chemistry 20040401
Waldenström's macroglobulinemia: prognostic factors and recent therapeutic advances. Clinical and experimental medicine 20040401
Hematologic toxicity of immunosuppressive treatment. Transplantation proceedings 20040401
Effect of purine-free low-malt liquor (happo-shu) on the plasma concentrations and urinary excretion of purine bases and uridine--comparison between purine-free and regular happo-shu. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040401
Pharmacology and mechanism of action of pemetrexed. Clinical lung cancer 20040401
Treatment of chronic lymphocytic leukemia. Seminars in oncology 20040401
Biological significance of the defense mechanisms against oxidative damage in nucleic acids caused by reactive oxygen species: from mitochondria to nuclei. Annals of the New York Academy of Sciences 20040401
Biosynthesis, accumulation and degradation of theobromine in developing Theobroma cacao fruits. Journal of plant physiology 20040401
Inhibitory effect of pyrimidine and purine nucleotides on the multiplication of Babesia gibsoni: possible cause of low parasitemia and simultaneous reticulocytosis in canine babesiosis. The Journal of veterinary medical science 20040401
For the record: the Francis Crick Archive at the Wellcome Library. Medical history 20040401
Recombination resulting in virulence shift in avian influenza outbreak, Chile. Emerging infectious diseases 20040401
Host factors and efficacy of antiretroviral treatment. The new microbiologica 20040401
Mutational, NMR, and NH exchange studies of the tight and selective binding of 8-oxo-dGMP by the MutT pyrophosphohydrolase. Biochemistry 20040330
Peroxynitrite formation from the simultaneous reduction of nitrite and oxygen by xanthine oxidase. FEBS letters 20040326
C-H to N substitution dramatically alters the sequence-specific DNA alkylation, cytotoxicity, and expression of human cancer cell lines. Journal of the American Chemical Society 20040324
Head-to-head (HH) and head-to-tail (HT) conformers of cis-bis guanine ligands bound to the [Re(CO)3]+ core. Inorganic chemistry 20040322
Structure and K+ ion-dependent stability of a parallel-stranded DNA quadruplex containing a core A-tetrad. Organic & biomolecular chemistry 20040321
Crystal structures of Escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium. Journal of molecular biology 20040319
[Treatment of T-cell prolymphocytic leukemia with monoclonal anti- CD52 antibody (alemtuzumab]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20040318
Xanthine oxidoreductase and cardiovascular disease: molecular mechanisms and pathophysiological implications. The Journal of physiology 20040316
5-N-Substituted-2-(substituted benzenesulphonyl) glutamines as antitumor agents. Part II: synthesis, biological activity and QSAR study. Bioorganic & medicinal chemistry 20040315
Synthesis and biological evaluation of 6-substituted purine and 9-beta-d-ribofuranosyl purine analogues. Bioorganic & medicinal chemistry 20040315
Deoxynucleic guanidine; synthesis and incorporation of purine nucleosides into positively charged DNG oligonucleotides. Bioorganic & medicinal chemistry 20040315
Synthesis and duplex DNA recognition studies of oligonucleotides containing a ureido isoindolin-1-one homo-N-nucleoside. A comparison of host-guest and DNA recognition studies. Bioorganic & medicinal chemistry 20040315
Synthesis of a potent transition-state inhibitor of 5'-deoxy-5'-methylthioadenosine phosphorylase. Journal of medicinal chemistry 20040311
Uric acid and diet--insights into the epidemic of cardiovascular disease. The New England journal of medicine 20040311
Purine-rich foods, dairy and protein intake, and the risk of gout in men. The New England journal of medicine 20040311
Inhibitors of Civ1 kinase belonging to 6-aminoaromatic-2-cyclohexyldiamino purine series as potent anti-fungal compounds. Biochimica et biophysica acta 20040311
Structures of purine 2'-deoxyribosyltransferase, substrate complexes, and the ribosylated enzyme intermediate at 2.0 A resolution. Biochemistry 20040309
G-rich oligonucleotide inhibits the binding of a nuclear protein to the Ki-ras promoter and strongly reduces cell growth in human carcinoma pancreatic cells. Biochemistry 20040309
Engineered delta ribozymes can simultaneously knock down the expression of the genes encoding uracil phosphoribosyltransferase and hypoxanthine-xanthine-guanine phosphoribosyltransferase in Toxoplasma gondii. International journal for parasitology 20040309
Toxoplasma gondii: the model apicomplexan. International journal for parasitology 20040309
Electrophysiological characterization of the human Na(+)/nucleoside cotransporter 1 (hCNT1) and role of adenosine on hCNT1 function. The Journal of biological chemistry 20040305
Metal coordination and imine-amine hydrogen bonding as the source of strongly shifted adenine pKa values. Journal of the American Chemical Society 20040303
Genomic organization and linkage via a bidirectional promoter of the AP-3 (adaptor protein-3) mu3A and AK (adenosine kinase) genes: deletion mutants of AK in Chinese hamster cells extend into the AP-3 mu3A gene. The Biochemical journal 20040301
Accumulation of 5-phosphoribosyl-1-pyrophosphate in human CCRF-CEM leukaemia cells treated with antifolates. The international journal of biochemistry & cell biology 20040301
Purine nucleoside phosphorylase deficiency associated with a dysplastic marrow morphology. Pediatric research 20040301
Molecular-genetic peculiarities of classical biotype Vibrio cholerae, the etiological agent of the last outbreak Asiatic cholera in Russia. Microbial pathogenesis 20040301
Subcellular localization of adenine and xanthine phosphoribosyltransferases in Leishmania donovani. Molecular and biochemical parasitology 20040301
Insect allantoinase: cDNA cloning, purification, and characterization of the native protein from the cat flea, Ctenocephalides felis. Insect biochemistry and molecular biology 20040301
Functional group recognition at the aminoacylation and editing sites of E. coli valyl-tRNA synthetase. RNA (New York, N.Y.) 20040301
Molecular requirements of the human nucleoside transporters hCNT1, hCNT2, and hENT1. Molecular pharmacology 20040301
Activation of 3-nitrobenzanthrone and its metabolites to DNA-damaging species in human B lymphoblastoid MCL-5 cells. Mutagenesis 20040301
Antineuropathic effects of the antibiotic derivative spicamycin KRN5500. Pain medicine (Malden, Mass.) 20040301
Recovering the true targets of specific ligands by virtual screening of the protein data bank. Proteins 20040301
The effects of tiazofurin on basal and amphetamine-induced motor activity in rats. Pharmacology, biochemistry, and behavior 20040301
Current approach to diagnosis and management of chronic lymphocytic leukemia. Mayo Clinic proceedings 20040301
Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements. PLoS biology 20040301
Uric acid: role in cardiovascular disease and effects of losartan. Current medical research and opinion 20040301
Cassette dosing pharmacokinetics of a library of 2,6,9-trisubstituted purine cyclin-dependent kinase 2 inhibitors prepared by parallel synthesis. Molecular cancer therapeutics 20040301
Suicide gene/prodrug therapy for pancreatic adenocarcinoma by E. coli purine nucleoside phosphorylase and 6-methylpurine 2'-deoxyriboside. Pancreas 20040301
Adenine auxotrophic mutants of Aspergillus oryzae: development of a novel transformation system with triple auxotrophic hosts. Bioscience, biotechnology, and biochemistry 20040301
Drug-induced pulmonary infection. Clinics in chest medicine 20040301
Purine nucleosides support the neurite outgrowth of primary rat cerebellar granule cells after hypoxia. European journal of cell biology 20040301
Complexes of copper(II) with adenosine or guanosine nucleosides, nucleotides 5'-monophosphate, 2'-deoxynucleosides or 2'-deoxynucleotides 5'-monophosphate in aqueous solution. Annali di chimica 20040301
Purine nucleoside phosphorylase inhibitors in T-cell malignancies. Current opinion in drug discovery & development 20040301
The chemodiversity of purine as a constituent of natural products. Chemistry & biodiversity 20040301
Nucleic acid synthesis in cancerous cells under the effect of gnidilatimonoein from Daphne mucronata. Life sciences 20040227
Probing the substrate recognition mechanism of the human MTH1 protein by nucleotide analogs. Journal of molecular biology 20040227
Synthesis of 2',5'-dideoxy-2-fluoroadenosine and 2',5'-dideoxy-2,5'-difluoroadenosine: potent P-site inhibitors of adenylyl cyclase. Journal of medicinal chemistry 20040226
The assignment of downfield proton resonances in an enzyme inhibitor complex using time-dependent saturation transferred NOEs. Journal of the American Chemical Society 20040225
Assignment of downfield proton resonances in purine nucleoside phosphorylase immucillin-H complex by saturation-transferred NOEs. Biochemistry 20040224
DNA substrate length and surrounding sequence affect the activation-induced deaminase activity at cytidine. The Journal of biological chemistry 20040220
One-electron attachment reaction of B- and Z-DNA modified by 8-bromo-2'-deoxyguanosine. The Journal of organic chemistry 20040220
Simultaneous analysis of theanine, chlorogenic acid, purine alkaloids and catechins in tea samples with the help of multi-dimension information of on-line high performance liquid chromatography/electrospray-mass spectrometry. Journal of pharmaceutical and biomedical analysis 20040218
Triple helix forming TRIPside molecules that target mixed purine/pyrimidine DNA sequences. Biochemistry 20040217
Transition state analysis for human and Plasmodium falciparum purine nucleoside phosphorylases. Biochemistry 20040217
Mechanism of primer synthesis by the herpes simplex virus 1 helicase-primase. Biochemistry 20040217
2-ClATP exerts anti-tumoural actions not mediated by P2 receptors in neuronal and glial cell lines. Biochemical pharmacology 20040215
Purine and pyrimidine-specific repression of the Escherichia coli carAB operon are functionally and structurally coupled. Journal of molecular biology 20040206
Separation of purine and pyrimidine bases by capillary electrophoresis using beta-cyclodextrin as an additive. Journal of pharmaceutical and biomedical analysis 20040204
The equilibrative nucleoside transporter family, SLC29. Pflugers Archiv : European journal of physiology 20040201
The concentrative nucleoside transporter family, SLC28. Pflugers Archiv : European journal of physiology 20040201
Interstitial purine metabolites in hearts with LV remodeling. American journal of physiology. Heart and circulatory physiology 20040201
Oral fludarabine has significant activity in patients with previously untreated chronic lymphocytic leukemia, and leads to increased STAT1 levels in vivo. Leukemia research 20040201
Xanthine nucleotide-specific G-protein alpha-subunits: a novel approach for the analysis of G-protein-mediated signal transduction. Naunyn-Schmiedeberg's archives of pharmacology 20040201
The influence of diazepam and midazolam on adenosine-induced forearm vasodilation in humans. Journal of cardiovascular pharmacology 20040201
The effect of maintenance immunosuppression medication on the change in kidney allograft function. Kidney international 20040201
Flux coupling analysis of genome-scale metabolic network reconstructions. Genome research 20040201
Solution, solid state and biological characterization of ruthenium(III)-DMSO complexes with purine base derivatives. Journal of inorganic biochemistry 20040201
Reverse transcriptase activity of hepatitis B virus (HBV) DNA polymerase within core capsid: interaction with deoxynucleoside triphosphates and anti-HBV L-deoxynucleoside analog triphosphates. Molecular pharmacology 20040201
Angiostatin-induced inhibition of endothelial cell proliferation/apoptosis is associated with the down-regulation of cell cycle regulatory protein cdk5. Journal of cellular biochemistry 20040201
Pentostatin (Nipent) in the treatment of chronic lymphocyte leukemia and hairy cell leukemia. Expert review of anticancer therapy 20040201
A modified immuno-enriched 32P-postlabeling method for analyzing the malondialdehyde-deoxyguanosine adduct, 3-(2-deoxy-beta-D-erythro-pentofuranosyl)- pyrimido[1,2-alpha]purin-10(3H)one in human tissue samples. Chemical research in toxicology 20040201
1,3-dimethyl-8-oxoisoguanine, a new purine from the New Zealand ascidian Pseudodistoma cereum. Natural product research 20040201
Adenosine deaminase 2 from chicken liver: purification, characterization, and N-terminal amino acid sequence. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20040201
Chronic lymphocytic leukaemia: up-dated recommendations on diagnosis and treatment. Onkologie 20040201
Structure-based approaches to the development of novel anti-malarials. Current drug targets 20040201
[Chronic lymphocytic leukemia--the old and the new]. Therapeutische Umschau. Revue therapeutique 20040201
Monoclonal antibodies in the treatment of chronic lymphoid leukemias. Leukemia & lymphoma 20040201
A three-hybrid approach to scanning the proteome for targets of small molecule kinase inhibitors. Chemistry & biology 20040201
Xanthine oxidase inhibition by 1,3-dipropyl-8-sulfophenylxanthine (DPSPX), an antagonist of adenosine receptors. Journal of enzyme inhibition and medicinal chemistry 20040201
Effect of caffeine on meiotic maturation of porcine oocytes. Zygote (Cambridge, England) 20040201
Immobilized Escherichia coli BL21 as a catalyst for the synthesis of adenine and hypoxanthine nucleosides. Chemistry & biodiversity 20040201
Distinct structural determinants of efficacy and sensitivity in the ligand-binding domain of cyclic nucleotide-gated channels. The Journal of biological chemistry 20040130
The AzgA purine transporter of Aspergillus nidulans. Characterization of a protein belonging to a new phylogenetic cluster. The Journal of biological chemistry 20040130
Crystal structure of fully ligated adenylosuccinate synthetase from Plasmodium falciparum. Journal of molecular biology 20040130
Stereochemical control of small molecule binding to bulged DNA: comparison of structures of spirocyclic enantiomer-bulged DNA complexes. Biochemistry 20040127
Mechanical stimulation releases nucleotides that activate P2Y1 receptors to trigger neural reflex chloride secretion in guinea pig distal colon. The Journal of comparative neurology 20040126
Mechanically evoked reflex electrogenic chloride secretion in rat distal colon is triggered by endogenous nucleotides acting at P2Y1, P2Y2, and P2Y4 receptors. The Journal of comparative neurology 20040126
Probing the solvent accessibility and electron density of adenine: oxidation of 7-deazaadenine in bent DNA and purine doublets. Inorganic chemistry 20040126
Platinum complexes with NH groups on the carrier ligand and with only one guanine or hypoxanthine derivative. Informative models for assessing relative nucleobase and nucleotide hydrogen-bond interactions with amine ligands in solution. Inorganic chemistry 20040126
Interactions at the dimer interface influence the relative efficiencies for purine nucleotide synthesis and pyrophosphorolysis in a phosphoribosyltransferase. Journal of molecular biology 20040123
Structures of human purine nucleoside phosphorylase complexed with inosine and ddI. Biochemical and biophysical research communications 20040123
Synthesis of chemically stabilized phosmidosine analogues and the structure--activity relationship of phosmidosine. The Journal of organic chemistry 20040123
Selective formation of stable triplexes including a TA or a CG interrupting site with new bicyclic nucleoside analogues (WNA). Journal of the American Chemical Society 20040121
Positive correlation between DNA polymerase alpha-primase pausing and mutagenesis within polypyrimidine/polypurine microsatellite sequences. Journal of molecular biology 20040116
Estimation of guanine deaminase using guanosine as a 'prosubstrate'. Analytical biochemistry 20040115
Capillary electrophoresis microchip with a carbon nanotube-modified electrochemical detector. Analytical chemistry 20040115
CD26 expression correlates with a reduced sensitivity to 2'-deoxycoformycin-induced growth inhibition and apoptosis in T-cell leukemia/lymphomas. Clinical cancer research : an official journal of the American Association for Cancer Research 20040115
Picomolar transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase and X-ray structure with MT-immucillin-A. Biochemistry 20040113
Synthesis and cytotoxicity of 9-(2-deoxy-2-alkyldithio-beta-D-arabinofuranosyl)purine nucleosides which are stable precursors to potential mechanistic probes of ribonucleotide reductases. Organic & biomolecular chemistry 20040107
Microchip capillary electrophoresis with a boron-doped diamond electrode for rapid separation and detection of purines. Journal of chromatography. A 20040102
Successful CD34+ cell mobilization by intermediate-dose Ara-C in chronic lymphocytic leukemia patients treated with sequential fludarabine and Campath-1H. Leukemia 20040101
Ammonium-induced internalisation of UapC, the general purine permease from Aspergillus nidulans. Fungal genetics and biology : FG & B 20040101
Correlation of electrophysiological and morphological characteristics of enteric neurons in the mouse colon. The Journal of comparative neurology 20040101
Tumor sensitization to purine analogs by E. coli PNP. Methods in molecular medicine 20040101
Current therapy of ulcerative colitis in children. Expert opinion on pharmacotherapy 20040101
The class C acid phosphatase of Helicobacter pylori is a 5' nucleotidase. Protein expression and purification 20040101
Dynamics of the IRE RNA hairpin loop probed by 2-aminopurine fluorescence and stochastic dynamics simulations. RNA (New York, N.Y.) 20040101
Purine bases at position 37 of tRNA stabilize codon-anticodon interaction in the ribosomal A site by stacking and Mg2+-dependent interactions. RNA (New York, N.Y.) 20040101
Antimycobacterial agents. 1. Thio analogues of purine. Journal of medicinal chemistry 20040101
Treatment options for newly diagnosed patients with chronic lymphocytic leukemia. Current hematology reports 20040101
Adenosine: an endogenous regulator of innate immunity. Trends in immunology 20040101
The diurnal rhythm of adenosine levels in the basal forebrain of young and old rats. Neuroscience 20040101
Genetic diversity and relationships in mulberry (genus Morus) as revealed by RAPD and ISSR marker assays. BMC genetics 20040101
Gene-directed enzyme prodrug therapy for prostate cancer in a mouse model that imitates the development of human disease. The journal of gene medicine 20040101
Adenine riboswitches and gene activation by disruption of a transcription terminator. Nature structural & molecular biology 20040101
Identification and comparative analysis of components from the signal recognition particle in protozoa and fungi. BMC genomics 20040101
Mobilization of xanthine oxidase from the gastrointestinal tract in acute pancreatitis. BMC gastroenterology 20040101
Pharmacologic immunosuppression. Frontiers in bioscience : a journal and virtual library 20040101
Inosine alleviates rat caerulein pancreatitis and pancreatitis-associated lung injury. Journal of gastroenterology 20040101
Uric acid administration for neuroprotection in patients with acute brain ischemia. Medical hypotheses 20040101
Peripheral blood mononuclear cell DNA 6-thioguanine metabolite levels correlate with decreased interferon-gamma production in patients with Crohn's disease on AZA therapy. Digestive diseases and sciences 20040101
Radiation-induced DNA damage: formation, measurement, and biochemical features. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20040101
Microwave-assisted organic synthesis using minivials to optimize and expedite the synthesis of diverse purine libraries. Journal of combinatorial chemistry 20040101
Leaf senescence--not just a 'wear and tear' phenomenon. Genome biology 20040101
[Effect of optimum jogging in a hot environment on uric acid metabolism]. Nihon eiseigaku zasshi. Japanese journal of hygiene 20040101
Nucleosides. IX. Synthesis of purine N(3),5'-cyclonucleosides and N(3),5'-cyclo-2',3'-seconucleosides via Mitsunobu reaction as TIBO-like derivatives. Nucleosides, nucleotides & nucleic acids 20040101
Synthesis of nucleoside libraries on solid support. I. N2,N6-disubstituted diaminopurine nucleosides. Nucleosides, nucleotides & nucleic acids 20040101
Synthesis of nucleoside libraries on solid support. II. 2,6,8-Trisubstituted purine nucleosides using 8-bromoguanosine as precursor. Nucleosides, nucleotides & nucleic acids 20040101
Mastocytosis: classification, diagnosis, and clinical presentation. Allergy and asthma proceedings 20040101
Prediction of Saccharomyces cerevisiae replication origins. Genome biology 20040101
Enriching for direct regulatory targets in perturbed gene-expression profiles. Genome biology 20040101
Pentostatin, chlorambucil and prednisone therapy for B-chronic lymphocytic leukemia: a phase I/II study by the Eastern Cooperative Oncology Group study E1488. Leukemia & lymphoma 20040101
DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse. Environmental and molecular mutagenesis 20040101
Synthesis and evaluation of ATP-binding site directed potential inhibitors of nucleoside triphosphatases/helicases and polymerases of hepatitis C and other selected Flaviviridae viruses. Antiviral chemistry & chemotherapy 20040101
Molecular recognition at purine and pyrimidine nucleotide (P2) receptors. Current topics in medicinal chemistry 20040101
Treatment options in chronic lymphocytic leukemia. The hematology journal : the official journal of the European Haematology Association 20040101
Clinical experience with fludarabine in indolent non-Hodgkin's lymphoma. The hematology journal : the official journal of the European Haematology Association 20040101
Treatment of hematological malignancies with allogeneic nonmyeloablative stem cell transplantation: conditioning regimens with fludarabine. The hematology journal : the official journal of the European Haematology Association 20040101
Future prospects for fludarabine-containing regimens in the treatment of hematological cancers. The hematology journal : the official journal of the European Haematology Association 20040101
Bacterial variations on the methionine salvage pathway. BMC microbiology 20040101
Collisionally-induced dissociation of purine antiviral agents: mechanisms of ion formation using gas phase hydrogen/deuterium exchange and electrospray ionization tandem mass spectrometry. European journal of mass spectrometry (Chichester, England) 20040101
New probes for microtubule dynamics. Chemistry & biology 20040101
Identification of a novel protein regulating microtubule stability through a chemical approach. Chemistry & biology 20040101
The over-representation of binary DNA tracts in seven sequenced chromosomes. BMC genomics 20040101
Differential metabolic effects on mitochondria by silica hydride using capillary electrophoresis. Journal of medicinal food 20040101
Mutation carrier testing in Lesch-Nyhan syndrome families: HPRT mutant frequency and mutation analysis with peripheral blood T lymphocytes. Genetic testing 20040101
Characterization of a nudix hydrolase from Deinococcus radiodurans with a marked specificity for (deoxy)ribonucleoside 5'-diphosphates. BMC biochemistry 20040101
Resistance to gemcitabine in a human follicular lymphoma cell line is due to partial deletion of the deoxycytidine kinase gene. BMC pharmacology 20040101
New insights into erythropoiesis: the roles of folate, vitamin B12, and iron. Annual review of nutrition 20040101
A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases. BMC bioinformatics 20040101
Adenosine deaminase activity and its isoenzyme pattern in women with recurrent spontaneous abortions. Gynecologic and obstetric investigation 20040101
Biochemical and mechanistic basis for the activity of nucleoside analogue inhibitors of HIV reverse transcriptase. Current topics in medicinal chemistry 20040101
The biochemical basis of the neurobehavioral abnormalities in the Lesch-Nyhan syndrome: a hypothesis. Medical hypotheses 20040101
Design, efficient synthesis, and anti-HIV activity of 4'-C-cyano- and 4'-C-ethynyl-2'-deoxy purine nucleosides. Nucleosides, nucleotides & nucleic acids 20040101
Creation of non-human primate neurogenetic disease models by gene targeting and nuclear transfer. Reproductive biology and endocrinology : RB&E 20040101
Xanthine, xanthosine and its nucleotides: solution structures of neutral and ionic forms, and relevance to substrate properties in various enzyme systems and metabolic pathways. Acta biochimica Polonica 20040101
Quantitative relationship between synonymous codon usage bias and GC composition across unicellular genomes. BMC evolutionary biology 20040101
Clofarabine. Drugs in R&D 20040101
Vascular physiology and pathology of circulating xanthine oxidoreductase: from nucleotide sequence to functional enzyme. Redox report : communications in free radical research 20040101
Assembly of splicing complexes on exon 11 of the human insulin receptor gene does not correlate with splicing efficiency in-vitro. BMC molecular biology 20040101
Systematic quantification of gene interactions by phenotypic array analysis. Genome biology 20040101
Shotgun proteomics of Methanococcus jannaschii and insights into methanogenesis. Journal of proteome research 20040101
Graph-based iterative Group Analysis enhances microarray interpretation. BMC bioinformatics 20040101
[Similarity of mutation spectra of the mitochondrial DNA hypervariable segment 1 in Homo and Pan species]. Molekuliarnaia biologiia 20040101
Phylogenetic profiling of the Arabidopsis thaliana proteome: what proteins distinguish plants from other organisms? Genome biology 20040101
Enzyme activities controlling adenosine levels in normal and neoplastic tissues. Medical oncology (Northwood, London, England) 20040101
Involvement of purinergic nerves in the NANC inhibitory junction potentials in pigeon oesophageal smooth muscle. Autonomic & autacoid pharmacology 20040101
Regulatory role of E-NTPase/E-NTPDase in Ca2+/Mg2+ transport via gated channel. Theoretical biology & medical modelling 20040101
Inheritance of urinary calculi in the Dalmatian. Journal of veterinary internal medicine 20040101
Discovery of estrogen receptor alpha target genes and response elements in breast tumor cells. Genome biology 20040101
Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably? Retrovirology 20040101
Complete mitochondrial genome sequence of Urechis caupo, a representative of the phylum Echiura. BMC genomics 20040101
Simple statistical models predict C-to-U edited sites in plant mitochondrial RNA. BMC bioinformatics 20040101
Regulation of milk lipid formation and secretion in the mouse mammary gland. Advances in experimental medicine and biology 20040101
Protection of pulmonary epithelial cells from oxidative stress by hMYH adenine glycosylase. Respiratory research 20040101
Genomic and proteomic adaptations to growth at high temperature. Genome biology 20040101
AIT-082 and methylprednisolone singly, but not in combination, enhance functional and histological improvement after acute spinal cord injury in rats. International journal of immunopathology and pharmacology 20040101
Purine analogs in leukemia. Advances in pharmacology (San Diego, Calif.) 20040101
Strickler-Berg analysis of excited singlet state dynamics in DNA and RNA nucleosides. Faraday discussions 20040101
[Thiaside diuretics in combination with inhibitors of angiotensin-converting enzyme in patients with diabetes mellitus type 2 comorbid with arterial hypertension]. Terapevticheskii arkhiv 20040101
New nucleoside analogs in the treatment of hematological disorders. Acta poloniae pharmaceutica 20040101
Aetiological factors in paediatric urolithiasis. Nephron. Clinical practice 20040101
Analysis of urinary nucleosides. IV. Identification of urinary purine nucleosides by liquid chromatography/electrospray mass spectrometry. Rapid communications in mass spectrometry : RCM 20040101
A probabilistic model for the evolution of RNA structure. BMC bioinformatics 20040101
Purification and properties of the Escherichia coli nucleoside transporter NupG, a paradigm for a major facilitator transporter sub-family. Molecular membrane biology 20040101
Immobilization and stabilization of recombinant multimeric uridine and purine nucleoside phosphorylases from Bacillus subtilis. Biomacromolecules 20040101
[Arterial hypertension in chronic glomerulonephritis: detectability and treatment efficacy]. Terapevticheskii arkhiv 20040101
Phylogenomic evidence supports past endosymbiosis, intracellular and horizontal gene transfer in Cryptosporidium parvum. Genome biology 20040101
Consensus clustering and functional interpretation of gene-expression data. Genome biology 20040101
Interactions of calf spleen purine nucleoside phosphorylase with 8-azaguanine, and a bisubstrate analogue inhibitor: implications for the reaction mechanism. Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
Amyloidosis and Waldenström's macroglobulinemia. Hematology. American Society of Hematology. Education Program 20040101
The influence of 2-chlorodeoxyadenosine (2-CdA) on the adenine energy charge and glutathione content of human erythrocytes. Cell biology international 20040101
Noise filtering and nonparametric analysis of microarray data underscores discriminating markers of oral, prostate, lung, ovarian and breast cancer. BMC bioinformatics 20040101
Estimating genomic coexpression networks using first-order conditional independence. Genome biology 20040101
Neurotrophin and Trk expression by cells of the human lamina cribrosa following oxygen-glucose deprivation. BMC neuroscience 20040101
Monoclonal antibodies in the treatment of chronic lymphocytic leukemia. Medical oncology (Northwood, London, England) 20040101
[Acute renal failure and 2,8-dihydroxyadeninuria]. Nephrologie 20040101
A two-way interface between limited Systems Biology Markup Language and R. BMC bioinformatics 20040101
Side-chain conformational restriction in template-competitive inhibitors of E. coli DNA polymerase I Klenow fragment: synthesis, structural characterization and inhibition activity. Nucleosides, nucleotides & nucleic acids 20040101
Hierarchical structure and modules in the Escherichia coli transcriptional regulatory network revealed by a new top-down approach. BMC bioinformatics 20040101
Effective anomerisation of 2'-deoxyadenosine derivatives during disaccharide nucleoside synthesis. Nucleosides, nucleotides & nucleic acids 20040101
Synthesis of (-)-DAPD. Nucleosides, nucleotides & nucleic acids 20040101
[Inherited disorders of purine and pyrimidine metabolism. State of art. Contribution for diagnosis]. Acta medica portuguesa 20040101
[The significance of free radicals and antioxidants due to the load induced by sport activity]. Ceskoslovenska fysiologie 20040101
[Principal infections in the oncology patient: practical treatment]. Anales del sistema sanitario de Navarra 20040101
Second malignancies and Richter's syndrome in patients with chronic lymphocytic leukemia. Hematology (Amsterdam, Netherlands) 20040101
G-protein-coupled receptor signaling, RGS proteins, and lymphocyte function. Critical reviews in immunology 20040101
[Tight binding transition state analogues of purine nucleoside phosphorylase--meaning, design and properties]. Postepy biochemii 20040101
Adenosine and adenine nucleotides as regulators of cerebral blood flow: roles of acidosis, cell swelling, and KATP channels. Critical reviews in neurobiology 20040101
[Interaction of preparation 'ATP-LONG' with distearoylphosphatidylcholine monolayer]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101
[Purine nucleotides of human erythrocytes--metabolism and regulation]. Postepy biochemii 20040101
Purine loading, stem-loops and Chargaff's second parity rule: a discussion of the application of elementary principles to early chemical observations. Applied bioinformatics 20040101
Purine bases and atheromatous plaque. International journal of immunopathology and pharmacology 20040101
Practical synthesis of 2'-deoxy-2'-fluoroarabinofuranosyl purine nucleosides by chemo-enzymatic method. Nucleic acids symposium series (2004) 20040101
Effects of 5-substituted pyrimidine nucleoside bases of WNA on stability of triplex DNA. Nucleic acids symposium series (2004) 20040101
Chemical synthesis of oxanine-contained oligodeoxynucleotides. Nucleic acids symposium series (2004) 20040101
Uncoupling Proteins in Amoeboid Eukaryotes, Acanthamoeba castellanii, and Dictyostelium discoideum. Toxicology mechanisms and methods 20040101
Perinatal asphyxia syndrome in the foal: review and a case report. Irish veterinary journal 20040101
Cellular and molecular mechanisms in environmental and occupational inhalation toxicology. GMS current topics in otorhinolaryngology, head and neck surgery 20040101
Toxicological assessment of noxious inhalants. GMS current topics in otorhinolaryngology, head and neck surgery 20040101
Probing the requirements for recognition and catalysis in Fpg and MutY with nonpolar adenine isosteres. Journal of the American Chemical Society 20031231
Crystal structure of human PNP complexed with guanine. Biochemical and biophysical research communications 20031219
Synthesis and biological evaluation of iodinated and fluorinated 9-(2-hydroxypropyl) and 9-(2-hydroxyethoxy)methyl purine nucleoside analogues. Journal of medicinal chemistry 20031218
Synthesis and evaluation of optically pure dioxolanes as inhibitors of hepatitis C virus RNA replication. Bioorganic & medicinal chemistry letters 20031215
Immunosuppression with FK778 and mycophenolate mofetil in a rat cardiac transplantation model. Transplantation 20031215
Cytokinin-induced differentiation of human myeloid leukemia HL-60 cells is associated with the formation of nucleotides, but not with incorporation into DNA or RNA. Biochimica et biophysica acta 20031207
Synthesis and molecular structure of new acyclic analogues of nucleotides with a 1,2-alkadienic skeleton. Organic & biomolecular chemistry 20031207
An unusual sugar conformation in the structure of an RNA/DNA decamer of the polypurine tract may affect recognition by RNase H. Journal of molecular biology 20031205
Purinergic-induced signaling in C11-MDCK cells inhibits the secretory Na-K-Cl cotransporter. American journal of physiology. Cell physiology 20031201
Neuroprotective effect of adenine on purkinje cell survival in rat cerebellar primary cultures. Journal of neuroscience research 20031201
Transfusion-associated GVHD after fludarabine therapy in a patient with systemic lupus erythematosus. Transfusion 20031201
Nucleobase pairing in expanded Watson-Crick-like genetic information systems. Structure (London, England : 1993) 20031201
The effect of a vegetarian and different omnivorous diets on urinary risk factors for uric acid stone formation. European journal of nutrition 20031201
Catalysis by nucleoside hydrolases. Current opinion in structural biology 20031201
Biological activity of inorganic arsenic and antimony reflects oxidation state in cultured human keratinocytes. Chemical research in toxicology 20031201
Maintenance therapy for inflammatory bowel disease. The American journal of gastroenterology 20031201
Peripheral T-cell lymphomas: diagnosis and management. Hematology/oncology clinics of North America 20031201
Efficacy of methylenecyclopropane analogs of nucleosides against herpesvirus replication in vitro. Nucleosides, nucleotides & nucleic acids 20031201
Synthesis and antiviral activity of 2-substituted analogs of triciribine. Nucleosides, nucleotides & nucleic acids 20031201
Synthesis and studies of 3'-C-trifluoromethyl-beta-D-ribonucleosides bearing the five naturally occurring nucleic acid bases. Nucleosides, nucleotides & nucleic acids 20031201
Selective pressure on the allantoicase gene during vertebrate evolution. Journal of molecular evolution 20031201
Modulation of Toll-like Receptor 9 Responses through Synthetic Immunostimulatory Motifs of DNA. Annals of the New York Academy of Sciences 20031201
Clofarabine. Bioenvision/ILEX. Current opinion in investigational drugs (London, England : 2000) 20031201
Variant Richter's syndrome: a rare case of classical Hodgkin's lymphoma developing in a patient with chronic lymphocytic leukemia treated with fludarabine. Leukemia & lymphoma 20031201
Extension and cleavage of the polypurine tract plus-strand primer by Ty1 reverse transcriptase. The Journal of biological chemistry 20031128
Structural basis for substrate specificity of Escherichia coli purine nucleoside phosphorylase. The Journal of biological chemistry 20031121
Synthesis of second-generation transition state analogues of human purine nucleoside phosphorylase. Journal of medicinal chemistry 20031120
Inhibition of caffeine biosynthesis in tea (Camellia sinensis) and coffee (Coffea arabica) plants by ribavirin. FEBS letters 20031120
Theoretical study of cisplatin binding to purine bases: why does cisplatin prefer guanine over adenine? Journal of the American Chemical Society 20031119
[Follicular lymphoma]. Orvosi hetilap 20031116
RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells. Cancer research 20031115
Elongation of oligonucleotide primers forming a triple helix on double-stranded DNA templates by purified DNA polymerases. Biochemical and biophysical research communications 20031114
The Drosophila melanogaster UMP-CMP kinase cDNA encodes an N-terminal mitochondrial import signal. Biochemical and biophysical research communications 20031114
An unusual oxidative ring transformation of purine to imidazo[1,5-c]imidazole. Organic letters 20031113
Eutectic phase polymerization of activated ribonucleotide mixtures yields quasi-equimolar incorporation of purine and pyrimidine nucleobases. Journal of the American Chemical Society 20031112
Pre-steady-state analysis of the nucleoside hydrolase of Trypanosoma vivax. Evidence for half-of-the-sites reactivity and rate-limiting product release. Biochemistry 20031111
An approach to the generation of simple analogues of the antitumour agent spicamycin. Organic & biomolecular chemistry 20031107
Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists. Journal of medicinal chemistry 20031106
How strong can the bend be on a DNA helix from cisplatin? DFT and MP2 quantum chemical calculations of cisplatin-bridged DNA purine bases. Inorganic chemistry 20031103
Early biochemical and histological alterations in rat corticoencephalic cell cultures following metabolic damage and treatment with modulators of mitochondrial ATP-sensitive potassium channels. Neurochemistry international 20031101
Interferon-gamma regulates nucleoside transport systems in macrophages through signal transduction and activator of transduction factor 1 (STAT1)-dependent and -independent signalling pathways. The Biochemical journal 20031101
Genomic organization and functional characterization of the human concentrative nucleoside transporter-3 isoform (hCNT3) expressed in mammalian cells. Pflugers Archiv : European journal of physiology 20031101
Functional evidence that ATP or a related purine is an inhibitory NANC neurotransmitter in the mouse jejunum: study on the identity of P2X and P2Y purinoceptors involved. British journal of pharmacology 20031101
Acute adenosinergic cardioprotection in ischemic-reperfused hearts. American journal of physiology. Heart and circulatory physiology 20031101
The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs. RNA (New York, N.Y.) 20031101
Adenosine stimulation of the proliferation of colorectal carcinoma cell lines. Roles of cell density and adenosine metabolism. Biochemical pharmacology 20031101
Antimycobacterial activity of 2-methyl-adenosine. The Journal of antimicrobial chemotherapy 20031101
Favorable interactions between enfuvirtide and 1-beta-D-2,6-diaminopurine dioxolane in vitro. Antimicrobial agents and chemotherapy 20031101
Capillary electrophoresis in diagnosis and monitoring of adenosine deaminase deficiency. Clinical chemistry 20031101
The use of mycophenolate mofetil in liver transplant recipients. Expert opinion on pharmacotherapy 20031101
Waldenström macroglobulinaemia. The Lancet. Oncology 20031101
Mycophenolate mofetil inhibits human Tenon fibroblast proliferation by guanosine depletion. The British journal of ophthalmology 20031101
Phase I clinical trial and pharmacokinetic study of the spicamycin analog KRN5500 administered as a 1-hour intravenous infusion for five consecutive days to patients with refractory solid tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 20031101
Purine and pyrimidine nucleotide metabolism in higher plants. Journal of plant physiology 20031101
Synthesis and antiviral activity of novel trans-2,2-dimethyl cyclopropyl nucleosides. Archives of pharmacal research 20031101
Emerging therapies for graft-versus-host disease. Expert opinion on emerging drugs 20031101
Neotrofin, a novel purine that induces NGF-dependent nociceptive nerve sprouting but not hyperalgesia in adult rat skin. Molecular and cellular neurosciences 20031101
[Hairy-cell leukemia: 30 cases and a review of the literature]. Annales de medecine interne 20031101
Chemical composition of some components of the arrestment pheromone of the black-legged tick, Ixodes scapularis (Acari: Ixodidae) and their use in tick control. Journal of medical entomology 20031101
Human alkyladenine DNA glycosylase uses acid-base catalysis for selective excision of damaged purines. Biochemistry 20031028
Structure-based incorporation of 6-methyl-8-(2-deoxy-beta-ribofuranosyl)isoxanthopteridine into the human telomeric repeat DNA as a probe for UP1 binding and destabilization of G-tetrad structures. The Journal of biological chemistry 20031024
Inhibition of primary colon carcinoma growth and liver metastasis by the A3 adenosine receptor agonist CF101. British journal of cancer 20031020
Mass spectrometric method for detecting carbon 13 enrichment introduced by folate coenzymes in uric acid. Analytical biochemistry 20031015
Rev binds specifically to a purine loop in the SL1 region of the HIV-1 leader RNA. The Journal of biological chemistry 20031010
Structural basis for inhibition of human PNP by immucillin-H. Biochemical and biophysical research communications 20031003
Docking and small angle X-ray scattering studies of purine nucleoside phosphorylase. Biochemical and biophysical research communications 20031003
Synthesis of a transition state analogue inhibitor of purine nucleoside phosphorylase via the Mannich reaction. Organic letters 20031002
Alpha-lipoic acid preconditioning reduces ischemia-reperfusion injury of the rat liver via the PI3-kinase/Akt pathway. American journal of physiology. Gastrointestinal and liver physiology 20031001
Selective enhancement of ifosfamide-induced toxicity in Chinese hamster ovary cells. Cancer chemotherapy and pharmacology 20031001
Cariporide enhances lactate clearance upon reperfusion but does not alter lactate accumulation during global ischaemia. Pflugers Archiv : European journal of physiology 20031001
Chemical inhibitors of cyclin-dependent kinases control proliferation, apoptosis and differentiation of oligodendroglial cells. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20031001
The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum. PLoS biology 20031001
Purine alkaloids in Paullinia. Phytochemistry 20031001
Crystal structures of 3-methyladenine DNA glycosylase MagIII and the recognition of alkylated bases. The EMBO journal 20031001
Granulomatous slack skin disease--disease features and response to pentostatin. British journal of haematology 20031001
Nucleosome position-dependent and -independent activation of HIS7 epression in Saccharomyces cerevisiae by different transcriptional activators. Eukaryotic cell 20031001
Better late than never for repair of miscoding lesions within a transcribed template. Molecular cell 20031001
Aging-related changes in myocardial purine metabolism and ischemic tolerance. Experimental gerontology 20031001
Thiosugars. X. Novel nucleoside analogues derived from 4-thio-L-lyxofuranose. Nucleosides, nucleotides & nucleic acids 20031001
Drug transport and drug resistance in African trypanosomes. Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20031001
Patterns of codon usage bias in three dicot and four monocot plant species. Genes & genetic systems 20031001
Clonal expansion of adult rat hepatic stem cell lines by suppression of asymmetric cell kinetics (SACK). Biotechnology and bioengineering 20030930
Cofactor determination and spectroscopic characterization of the selenium-dependent purine hydroxylase from Clostridium purinolyticum. Biochemistry 20030930
An oxidized purine nucleoside triphosphatase, MTH1, suppresses cell death caused by oxidative stress. The Journal of biological chemistry 20030926
Cationic lipids and cationic ligands induce DNA helix denaturation: detection of single stranded regions by KMnO4 probing. FEBS letters 20030925
DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine). Journal of the American Chemical Society 20030924
Structure of avian AICAR transformylase with a multisubstrate adduct inhibitor beta-DADF identifies the folate binding site. Biochemistry 20030923
Asymmetric synthesis of oxygen heterocycles via Pd-catalyzed dynamic kinetic asymmetric transformations: application to nucleosides. Chemistry (Weinheim an der Bergstrasse, Germany) 20030922
Biochemical and three-dimensional-structural study of the specific inhibition of protein kinase CK2 by [5-oxo-5,6-dihydroindolo-(1,2-a)quinazolin-7-yl]acetic acid (IQA). The Biochemical journal 20030915
Determination of phosphate in nanomolar range by an enzyme-coupling fluorescent method. Analytical biochemistry 20030915
2,6,8,9-tetrasubstituted purines as new CDK1 inhibitors. Bioorganic & medicinal chemistry letters 20030915
Bone-targeted 2,6,9-trisubstituted purines: novel inhibitors of Src tyrosine kinase for the treatment of bone diseases. Bioorganic & medicinal chemistry letters 20030915
Evidence for assembly-dependent folding of protein and RNA in an icosahedral virus. Virology 20030915
Equilibrative nucleoside transporters of Arabidopsis thaliana. cDNA cloning, expression pattern, and analysis of transport activities. The Journal of biological chemistry 20030912
Effects of purine nucleosides on the in vitro growth of Cryptosporidium parvum. FEMS microbiology letters 20030912
Mutagenic and inhibitory effects of ribavirin on hepatitis C virus RNA polymerase. Biochemistry 20030909
Development of donor-acceptor modified DNA hairpins for the investigation of charge hopping kinetics in DNA. Chemical communications (Cambridge, England) 20030907
A biochemical characterization of the adeno-associated virus Rep40 helicase. The Journal of biological chemistry 20030905
ATP and ADP hydrolysis in brain membranes of zebrafish (Danio rerio). Life sciences 20030905
Unprecedented head-to-head conformers of d(GpG) bound to the antitumor active compound tetrakis (mu-carboxylato)dirhodium(II,II). Journal of the American Chemical Society 20030903
Novel binding interactions of the DNA fragment d(pGpG) cross-linked by the antitumor active compound tetrakis(mu-carboxylato)dirhodium(II,II). Journal of the American Chemical Society 20030903
Solution structure and NH exchange studies of the MutT pyrophosphohydrolase complexed with Mg(2+) and 8-oxo-dGMP, a tightly bound product. Biochemistry 20030902
Signalling from adenosine receptors to mitogen-activated protein kinases. Cellular signalling 20030901
Glutamine and the maintenance of meiotic arrest in mouse oocytes: influence of culture medium, glucose, and cumulus cells. Molecular reproduction and development 20030901
Low levels of endogenous oxidative damage cluster levels in unirradiated viral and human DNAs. Free radical biology & medicine 20030901
Purine and pyrimidine metabolites in children's urine. Clinica chimica acta; international journal of clinical chemistry 20030901
Cutaneous reactions in hairy cell leukaemia treated with 2-chlorodeoxyadenosine and allopurinol. British journal of haematology 20030901
Allopurinol improves cardiac dysfunction after ischemia-reperfusion via reduction of oxidative stress in isolated perfused rat hearts. Circulation journal : official journal of the Japanese Circulation Society 20030901
Role of urinary inhibitors of crystallization in uric acid nephrolithiasis: Dalmatian dog model. Urology 20030901
Potential chemotherapeutic targets in the purine metabolism of parasites. Pharmacology & therapeutics 20030901
Carbocyclic analogues of nucleosides from bis-(Hydroxymethyl)-cyclopentane: synthesis, antiviral and cytostatic activities of adenosine, inosine and uridine analogues. Chemical & pharmaceutical bulletin 20030901
Uric acid stone disease. Frontiers in bioscience : a journal and virtual library 20030901
[Cloning, expression and characterization of the hypoxanthine-guanine phosphoribosyltransferase mutants from T. tengcongensis]. Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030901
Lymphocyte DNA damage precedes DNA repair or cell death after orthopaedic surgery under general anaesthesia. Mutagenesis 20030901
Antioxidant and prooxidant properties of caffeine, theobromine and xanthine. Medical science monitor : international medical journal of experimental and clinical research 20030901
Influence of diet on growth yields of rumen micro-organisms in vitro and in vivo: influence on growth yield of variable carbon fluxes to fermentation products. The British journal of nutrition 20030901
Platinum complexes of diaminocarboxylic acids and their ethyl ester derivatives: the effect of the chelate ring size on antitumor activity and interactions with GMP and DNA. Journal of inorganic biochemistry 20030901
Nigral glutathione deficiency is not specific for idiopathic Parkinson's disease. Movement disorders : official journal of the Movement Disorder Society 20030901
[Non-myeloablative or reduced intensity stem cell transplantation preparative regimens]. Nihon rinsho. Japanese journal of clinical medicine 20030901
[Mini-transplantation for solid tumors]. Nihon rinsho. Japanese journal of clinical medicine 20030901
Excessive purine degradation during semi-ischemic forearm test in patients with diabetes mellitus. Internal medicine (Tokyo, Japan) 20030901
Epidemic and nonepidemic multidrug-resistant Enterococcus faecium. Emerging infectious diseases 20030901
[Urate transporter and renal hypouricemia]. Rinsho byori. The Japanese journal of clinical pathology 20030901
Synthesis and antiviral activity of novel C-methyl branched cyclopropyl nucleosides. Archives of pharmacal research 20030901
The influence of imatinib mesylate (STI571) used alone or in combination with purine nucleoside analogues on the normal and chronic myelogenous leukaemia progenitor cells in vitro. Leukemia & lymphoma 20030901
Cardiac adaptation to endurance exercise in rats. Molecular and cellular biochemistry 20030901
Molecular and functional characterization of the first nucleobase transporter gene from African trypanosomes. Molecular and biochemical parasitology 20030831
Crystal structure of human purine nucleoside phosphorylase at 2.3A resolution. Biochemical and biophysical research communications 20030829
Crystal structure of human purine nucleoside phosphorylase complexed with acyclovir. Biochemical and biophysical research communications 20030829
[The place of mycophenolate mofetil in glomerular diseases]. Presse medicale (Paris, France : 1983) 20030823
Achieving the ultimate physiological goal in transition state analogue inhibitors for purine nucleoside phosphorylase. The Journal of biological chemistry 20030822
Atoms-in-molecules study of the genetically encoded amino acids. III. Bond and atomic properties and their correlations with experiment including mutation-induced changes in protein stability and genetic coding. Proteins 20030815
A consensus-binding structure for adenine at the atomic level permits searching for the ligand site in a wide spectrum of adenine-containing complexes. Proteins 20030815
MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine. The Journal of biological chemistry 20030808
Selectivity of purine alkylation by a quinone methide. Kinetic or thermodynamic control? The Journal of organic chemistry 20030808
[Avoid purine-rich foods, drink a lot, reduce weight. The most important recipes against hyperuricemia]. MMW Fortschritte der Medizin 20030807
Synthesis and properties of oligo-2'-deoxyribonucleotides containing internucleotidic phosphoramidate linkages modified with pendant groups ending with either two amino or two hydroxyl functions. Bioorganic & medicinal chemistry 20030805
Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans. Chembiochem : a European journal of chemical biology 20030804
Thymidine and hypoxanthine protection patterns of the folic acid-enhanced synergies for combinations of trimetrexate plus a polyglutamylatable inhibitor of purine or thymidylate synthesis against human ileocecal HCT-8 cells. International journal of oncology 20030801
Use of nucleotide analogs by class I and class II CCA-adding enzymes (tRNA nucleotidyltransferase): deciphering the basis for nucleotide selection. RNA (New York, N.Y.) 20030801
Leflunomide treatment of Crohn's disease patients intolerant to standard immunomodulator therapy. Journal of clinical gastroenterology 20030801
Purine and sugar chemistry on solid phase--100 years after the Emil Fischer's Chemistry Nobel Prize 1902. Combinatorial chemistry & high throughput screening 20030801
Solvation of nucleosides in aqueous mixtures of organic solvents: relevance to DNA open basepairs. Biophysical journal 20030801
Interaction centres of purine nucleotides: adenosine-5'-diphosphate and adenosine-5'-triphosphate in their reactions with tetramines and Cu(II) ions. Journal of inorganic biochemistry 20030801
Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum. Biochemical and biophysical research communications 20030801
Oral choline decreases brain purine levels in lithium-treated subjects with rapid-cycling bipolar disorder: a double-blind trial using proton and lithium magnetic resonance spectroscopy. Bipolar disorders 20030801
Disease activity and pretreatment, rather than hypogammaglobulinaemia, are major risk factors for infectious complications in patients with chronic lymphocytic leukaemia. British journal of haematology 20030801
Cytosolic and mitochondrial deoxyribonucleotidases: activity with substrate analogs, inhibitors and implications for therapy. Biochemical pharmacology 20030801
Carbohydrates digestibility and faecal nitrogen excretion in rats fed raw or germinated faba bean (Vicia faba)- and chickpea (Cicer arietinum)-based diets. The British journal of nutrition 20030801
Genetic variation in genes associated with arsenic metabolism: glutathione S-transferase omega 1-1 and purine nucleoside phosphorylase polymorphisms in European and indigenous Americans. Environmental health perspectives 20030801
Identification of trans-dominant modifiers of Prat expression in Drosophila melanogaster. Genetics 20030801
Alemtuzumab therapy in B-cell lymphoproliferative disorders. Seminars in oncology 20030801
Four cases of red blood cell aplasia in association with the use of mycophenolate mofetil in renal transplant patients. Clinical nephrology 20030801
Nonmyeloablative transplantation for lymphoma. Current treatment options in oncology 20030801
Early reappearance of primary solid cancer in patients treated with purine analogs. Journal of chemotherapy (Florence, Italy) 20030801
A novel GT-mismatch binding protein that recognizes strict DNA sequences with high affinity. The Tohoku journal of experimental medicine 20030801
[Inhibition of respiratory syncytial virus replication in cultured cells by RNA-cleaving DNAzyme]. Zhonghua er ke za zhi = Chinese journal of pediatrics 20030801
Adenosine extracellular levels in human brain gliomas: an intraoperative microdialysis study. Neuroscience letters 20030731
Thyroid hormone upregulates ecto-5'-nucleotidase/CD73 in C6 rat glioma cells. Molecular and cellular endocrinology 20030731
Identification and characterisation of high affinity nucleoside and nucleobase transporters in Toxoplasma gondii. International journal for parasitology 20030730
Synthesis of pyrene and benzo[a]pyrene adducts at the exocyclic amino groups of 2'-deoxyadenosine and 2'-deoxyguanosine by a palladium-mediated C-N bond-formation strategy. The Journal of organic chemistry 20030725
Solution structure of a wedge-shaped synthetic molecule at a two-base bulge site in DNA. Biochemistry 20030722
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases: highly potent 2,6-Difluorophenacyl analogues. Bioorganic & medicinal chemistry letters 20030721
Exploring structure-activity relationships of transition state analogues of human purine nucleoside phosphorylase. Journal of medicinal chemistry 20030717
3-Bromopyrazolo[3,4-d]pyrimidine 2'-deoxy-2'-fluoro-beta-D-arabinonucleosides: modified DNA constituents with an unusually rigid sugar N-conformation. The Journal of organic chemistry 20030711
An efficient synthesis of 2-substituted 6-methylpurine bases and nucleosides by Fe- or Pd-catalyzed cross-coupling reactions of 2,6-dichloropurines. The Journal of organic chemistry 20030711
Sequence- and regioselectivity in the montmorillonite-catalyzed synthesis of RNA. Journal of the American Chemical Society 20030709
Porin OmpP2 of Haemophilus influenzae shows specificity for nicotinamide-derived nucleotide substrates. The Journal of biological chemistry 20030704
Adherent leukocytes prevent adenosine formation and impair endothelial barrier function by Ecto-5'-nucleotidase/CD73-dependent mechanism. The Journal of biological chemistry 20030704
Identification of the antineoplastic agent 6-mercaptopurine as an activator of the orphan nuclear hormone receptor Nurr1. The Journal of biological chemistry 20030704
DNA-protein cross-link formation mediated by oxanine. A novel genotoxic mechanism of nitric oxide-induced DNA damage. The Journal of biological chemistry 20030704
Simultaneous determination of orthophosphate and total phosphates (inorganic phosphates plus purine nucleotides) using a bioamperometric flow-injection system made up by a 16-way switching valve. Talanta 20030704
Characterisation of an uridine-specific binding site in rat cerebrocortical homogenates. Neurochemistry international 20030701
Posttranslational inactivation of human xanthine oxidoreductase by oxygen under standard cell culture conditions. American journal of physiology. Cell physiology 20030701
Arsenate reduction in human erythrocytes and rats--testing the role of purine nucleoside phosphorylase. Toxicological sciences : an official journal of the Society of Toxicology 20030701
Variation between observed and true Terminal Restriction Fragment length is dependent on true TRF length and purine content. Journal of microbiological methods 20030701
Soluble purine-converting enzymes circulate in human blood and regulate extracellular ATP level via counteracting pyrophosphatase and phosphotransfer reactions. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701
Gene expression patterns as potential molecular biomarkers for malignant transformation in human keratinocytes treated with MNNG, arsenic, or a metal mixture. Toxicological sciences : an official journal of the Society of Toxicology 20030701
Fludarabine plus cyclophosphamide for the treatment of advanced chronic lymphocytic leukemia. European journal of haematology 20030701
Expression profiling of endometrium from women with endometriosis reveals candidate genes for disease-based implantation failure and infertility. Endocrinology 20030701
A single intravenous injection of KRN5500 (antibiotic spicamycin) produces long-term decreases in multiple sensory hypersensitivities in neuropathic pain. Anesthesia and analgesia 20030701
Active site mutants of Drosophila melanogaster multisubstrate deoxyribonucleoside kinase. European journal of biochemistry 20030701
Interpretation of fluorescence decays using a power-like model. Biophysical journal 20030701
The mosaic of immunosuppressive drugs. Molecular immunology 20030701
Dose reduction of coadministered 6-mercaptopurine decreases myelotoxicity following high-dose methotrexate in childhood leukemia. Leukemia 20030701
High complete response rate after allogeneic hematopoietic stem cell transplantation with reduced-intensity conditioning regimens in advanced malignant lymphoma. Bone marrow transplantation 20030701
Photochemical cross-linking of Escherichia coli Fpg protein to DNA duplexes containing phenyl(trifluoromethyl)diazirine groups. European journal of biochemistry 20030701
Phosphoribosylpyrophosphate synthetase overactivity as a cause of uric acid overproduction in a young woman. Arthritis and rheumatism 20030701
A purL mutant of Sinorhizobium fredii HH103 is symbiotically defective and altered in its lipopolysaccharide. Microbiology (Reading, England) 20030701
Rituximab therapy for follicular lymphoma: a comprehensive review of its efficacy as primary treatment, treatment for relapsed disease, re-treatment and maintenance. Haematologica 20030701
[Anti-inflammatory constituents, aloesin and aloemannan in Aloe species and effects of tanshinon VI in Salvia miltiorrhiza on heart]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030701
Applications of triple-stranded nucleic acid structures to DNA purification, detection and analysis. Expert review of molecular diagnostics 20030701
Biopharmaceutical characterization of some synthetic purine drugs. Die Pharmazie 20030701
Electrochemical tagging of urate: developing new redox probes. The Analyst 20030701
Reduced-intensity allogeneic stem cell transplantation. Current hematology reports 20030701
Role of IMP-selective 5'-nucleotidase (cN-II) in hematological malignancies. Leukemia & lymphoma 20030701
Cloning, heterologous expression, and in situ characterization of the first high affinity nucleobase transporter from a protozoan. The Journal of biological chemistry 20030627
Impaired cortical energy metabolism but not major antioxidant defenses in experimental bacterial meningitis. Brain research 20030627
Synthesis and antiviral evaluation of 2'-deoxy-2'-C-trifiuoromethyl beta-D-ribonucleoside analogues bearing the five naturally occurring nucleic acid bases. Organic & biomolecular chemistry 20030621
A multicenter, randomized, placebo controlled, multiple-dose, safety and pharmacokinetic study of AIT-082 (Neotrofin) in mild Alzheimer's disease patients. Life sciences 20030620
Increased sensitivity to gemcitabine of P-glycoprotein and multidrug resistance-associated protein-overexpressing human cancer cell lines. British journal of cancer 20030616
2,6-Diamino-5,8-diaza-7,9-dicarba-purine. Organic letters 20030612
C-Nucleosidations with 2,6-diamino-5,8-diaza-7,9-dicarba-purine. Organic letters 20030612
Activating omega-6 polyunsaturated fatty acids and inhibitory purine nucleotides are high affinity ligands for novel mitochondrial uncoupling proteins UCP2 and UCP3. The Journal of biological chemistry 20030606
One-pot TiO2-catalyzed synthesis of nucleic bases and acyclonucleosides from formamide: implications for the origin of life. Chembiochem : a European journal of chemical biology 20030606
High-level activation by a duodenum-specific enhancer requires functional GATA binding sites. American journal of physiology. Gastrointestinal and liver physiology 20030601
KRN5500: a novel therapeutic agent with in vitro activity against human B-cell chronic lymphocytic leukemia cells mediates cytotoxicity via the intrinsic pathway of apoptosis. Blood 20030601
Theoretical ab initio study of the effects of methylation on structure and stability of G:C Watson-Crick base pair. Journal of biomolecular structure & dynamics 20030601
Comparative analysis of the ATP-binding sites of Hsp90 by nucleotide affinity cleavage: a distinct nucleotide specificity of the C-terminal ATP-binding site. European journal of biochemistry 20030601
Cutting edge: Monarch-1: a pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes. Journal of immunology (Baltimore, Md. : 1950) 20030601
Expression of genes for certain enzymes of pyrimidine and purine salvage pathway in peripheral blood leukocytes collected from patients with Graves' or Hashimoto's disease. Journal of cellular biochemistry 20030601
Toll-like receptor 9: modulation of recognition and cytokine induction by novel synthetic CpG DNAs. Biochemical Society transactions 20030601
Cloning, expression and preliminary crystallographic studies of the potential drug target purine nucleoside phosphorylase from Schistosoma mansoni. Acta crystallographica. Section D, Biological crystallography 20030601
Mechanism of action of purine analogues in chronic lymphocytic leukaemia. British journal of haematology 20030601
Mechanism of inhibition of T-acute lymphoblastic leukemia cells by PNP inhibitor--BCX-1777. International immunopharmacology 20030601
Homo- and heteroexchange of adenine nucleotides and nucleosides in rat hippocampal slices by the nucleoside transport system. British journal of pharmacology 20030601
Functional characterization of a H+/nucleoside co-transporter (CaCNT) from Candida albicans, a fungal member of the concentrative nucleoside transporter (CNT) family of membrane proteins. Yeast (Chichester, England) 20030601
Homozygous deletion of CDKN2A and codeletion of the methylthioadenosine phosphorylase gene in the majority of pleural mesotheliomas. Clinical cancer research : an official journal of the American Association for Cancer Research 20030601
Allantoin, the oxidation product of uric acid is present in chicken and turkey plasma. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030601
New tricks for an old dogma: riboswitches as cis-only regulatory systems. Molecular cell 20030601
Regulation of bone resorption and formation by purines and pyrimidines. Trends in pharmacological sciences 20030601
Molecular characterization of 5'-deoxy-5'-methylthioadenosine phosphorylase-deficient mutant clones of murine lymphoma cell line R1.1. Cancer science 20030601
Extracellular metabolism of nucleotides in neuroblastoma x glioma NG108-15 cells determined by capillary electrophoresis. Cellular and molecular neurobiology 20030601
Altering soluble and potentially rumen degradable protein for prepubertal Holstein heifers. Journal of dairy science 20030601
Effects of a polymer-coated urea product on nitrogen metabolism in lactating Holstein dairy cattle. Journal of dairy science 20030601
Effects of increasing dietary protein on nutrient utilization in heifers. Journal of dairy science 20030601
Phase II study of cladribine (2-chlorodeoxyadenosine) in relapsed or refractory adult T-cell leukemia-lymphoma. International journal of hematology 20030601
Functional differences in nucleoside and nucleobase transporters expressed on the rabbit corneal epithelial cell line (SIRC) and isolated rabbit cornea. AAPS pharmSci 20030601
Phase I and pharmacokinetic study of KRN5500, a spicamycin derivative, for patients with advanced solid tumors. Japanese journal of clinical oncology 20030601
Riboswitches control fundamental biochemical pathways in Bacillus subtilis and other bacteria. Cell 20030530
Over-the-barrier transition state analogues and crystal structure with Mycobacterium tuberculosis purine nucleoside phosphorylase. Biochemistry 20030527
Mammalian fibroblasts lacking mitochondrial NAD+-dependent methylenetetrahydrofolate dehydrogenase-cyclohydrolase are glycine auxotrophs. The Journal of biological chemistry 20030523
Metal coordination-based inhibitors of adenylyl cyclase: novel potent P-site antagonists. Journal of medicinal chemistry 20030522
Base sequence effects in radical cation migration in duplex DNA: support for the polaron-like hopping model. Journal of the American Chemical Society 20030521
Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases. Biochemistry 20030520
Differential control of cell cycle, proliferation, and survival of primary T lymphocytes by purine and pyrimidine nucleotides. Journal of immunology (Baltimore, Md. : 1950) 20030515
Selective C-arylation of free (NH)-heteroarenes via catalytic C-H bond functionalization. Journal of the American Chemical Society 20030507
Toward novel DNA binding metal complexes: structure and basic kinetic data of [M(9MeG)2(CH3OH)(CO)3]+(M = 99Tc, Re). Inorganic chemistry 20030505
L-serine in disease and development. The Biochemical journal 20030501
Development and application of bioprobes for Mammalian cell cycle analyses. Current medicinal chemistry 20030501
P2X(2) purine receptor immunoreactivity of intraganglionic laminar endings in the mouse gastrointestinal tract. Cell and tissue research 20030501
The role of context-dependent mutations in generating compositional and codon usage bias in grass chloroplast DNA. Journal of molecular evolution 20030501
The PRAT purine synthesis gene duplication in Drosophila melanogaster and Drosophila virilis is associated with a retrotransposition event and diversification of expression patterns. Journal of molecular evolution 20030501
Successful treatment of a patient with hairy cell leukemia and pentostatin-induced autoimmune thrombocytopenia with rituximab. American journal of hematology 20030501
DNA is a target of the photodynamic effects elicited in A2E-laden RPE by blue-light illumination. Investigative ophthalmology & visual science 20030501
Effect of exercise and beer on the plasma concentration and urinary excretion of purine bases. The Journal of rheumatology 20030501
Proteome analysis of the purine stimulon from Lactococcus lactis. Proteomics 20030501
[Studies on the syntheses of the hypermodified nucleosides of phenylalanine transfer ribonucleic acids]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20030501
Synchrony of nutrient supply to the rumen and dietary energy source and their effects on the growth and metabolism of lambs. Journal of animal science 20030501
Changes in ectonucleotidase activities in rat Sertoli cells during sexual maturation. Molecular and cellular biochemistry 20030501
Translation Inhibition of Capped and Uncapped Viral RNAs Mediated by Ribosome-Inactivating Proteins. Phytopathology 20030501
Clear distinction of purine bases on the complementary strand by a fluorescence change of a novel fluorescent nucleoside. Journal of the American Chemical Society 20030430
Effects of inosine on axonal regeneration of axotomized retinal ganglion cells in adult rats. Neuroscience letters 20030424
Review of a promising new agent--pemetrexed disodium. Cancer 20030415
A substantial level of donor hematopoietic chimerism is required to protect donor-specific islet grafts in diabetic NOD mice. Transplantation 20030415
The role of the minor groove substituents in indirect readout of DNA sequence by 434 repressor. The Journal of biological chemistry 20030411
Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus. Journal of medicinal chemistry 20030410
Gene expression patterns define pathways correlated with loss of differentiation in lung adenocarcinomas. FEBS letters 20030410
Adenosine is the primary precursor of all purine nucleotides in Trichomonas vaginalis. Molecular and biochemical parasitology 20030403
A Leishmania major nucleobase transporter responsible for allopurinol uptake is a functional homolog of the Trypanosoma brucei H2 transporter. Molecular pharmacology 20030401
Binding of fatty acids to the uncoupling protein from brown adipose tissue mitochondria. Archives of biochemistry and biophysics 20030401
Role of MHC class I in immune surveillance of mitochondrial DNA integrity. Journal of immunology (Baltimore, Md. : 1950) 20030401
Structural studies on ADP activation of mammalian glutamate dehydrogenase and the evolution of regulation. Biochemistry 20030401
Transport of cytokinins mediated by purine transporters of the PUP family expressed in phloem, hydathodes, and pollen of Arabidopsis. The Plant journal : for cell and molecular biology 20030401
Uptake and release of [3H]adenosine in human dental pulp. Archives of oral biology 20030401
Pentostatin and cyclophosphamide: an effective new regimen in previously treated patients with chronic lymphocytic leukemia. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030401
Mixed ligand complexes of platinum(II) and palladium(II) with cytokinin-derived compounds Bohemine and Olomoucine: X-ray structure of [Pt(BohH+-N7)Cl(3)].9/5H2O [Boh=6-(benzylamino)-2-[(3-(hydroxypropyl)-amino]-9-isopropylpurine, Bohemine]. Journal of inorganic biochemistry 20030401
Nucleotides modulate the activity of aspartate racemase of Scapharca broughtonii. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20030401
Intravenous and oral pharmacokinetic study of BCX-1777, a novel purine nucleoside phosphorylase transition-state inhibitor. In vivo effects on blood 2'-deoxyguanosine in primates. International immunopharmacology 20030401
One-step purification of 5-enolpyruvylshikimate-3-phosphate synthase enzyme from Mycobacterium tuberculosis. Protein expression and purification 20030401
Covalent binding of leukotriene A4 to DNA and RNA. Chemical research in toxicology 20030401
Tubular injury: the first symptom of hypertensive kidney involvement? Medical science monitor : international medical journal of experimental and clinical research 20030401
Adenosine 5'-triphosphate (ATP) is an excitatory cotransmitter with noradrenaline to the smooth muscle of the rat prostate gland. British journal of pharmacology 20030401
Special sensitization pattern in adenosine-induced myocardial responses after thyroxine-treatment. Journal of pharmacological sciences 20030401
Fludarabine in Waldenstrom's macroglobulinemia. Seminars in oncology 20030401
Treatment of Waldenstrom's macroglobulinemia with clarithromycin, low-dose thalidomide, and dexamethasone. Seminars in oncology 20030401
Role for high-dose therapy with autologous hematopoietic stem cell support in Waldenstrom's macroglobulinemia. Seminars in oncology 20030401
Autologous and allogeneic stem cell transplantation in Waldenstrom's macroglobulinemia: review of the literature and future directions. Seminars in oncology 20030401
Pemetrexed (Alimta): a novel multitargeted antifolate agent. Expert review of anticancer therapy 20030401
Overview of non-Hodgkin's lymphoma: biology, staging, and treatment. Seminars in oncology 20030401
Purine derivative excretion in dairy cows: endogenous excretion and the effect of exogenous nucleic acid supply. Journal of dairy science 20030401
Effect of feeding protein supplements of differing degradability on omasal flow of microbial and undegraded protein. Journal of dairy science 20030401
Effects of varying dietary protein and energy levels on the production of lactating dairy cows. Journal of dairy science 20030401
[Enzymes of purine metabolism of lymphocytes and eosinophiles in bronchial asthma]. Klinicheskaia laboratornaia diagnostika 20030401
The purine nucleoside cycle in cell-free extracts of rat brain: evidence for the occurrence of an inosine and a guanosine cycle with distinct metabolic roles. Cellular and molecular life sciences : CMLS 20030401
Intraocular adenosine levels in normal and ocular-hypertensive patients. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20030401
Involvement of purinergic signaling in cardiovascular diseases. Drug news & perspectives 20030401
Synthesis, structural studies, and biological evaluation of some purine substituted 1-aminocyclopropane-1-carboxylic acids and 1-amino-1-hydroxymethylcyclopropanes. Nucleosides, nucleotides & nucleic acids 20030401
Mechanisms of release of ATP from vascular purinergic nerves. Autonomic & autacoid pharmacology 20030401
DFT analysis of NMR scalar interactions across the glycosidic bond in DNA. Journal of the American Chemical Society 20030326
1H-Pyrazolo[3,4-b]pyridine inhibitors of cyclin-dependent kinases. Bioorganic & medicinal chemistry letters 20030324
Synthesis of imidazopyridines and purines as potent inhibitors of leukotriene A4 hydrolase. Bioorganic & medicinal chemistry letters 20030324
Polyethylene glycol-conjugated adenosine phosphorylase: development of alternative enzyme therapy for adenosine deaminase deficiency. Biochimica et biophysica acta 20030320
Identification of RNA ligands that bind hepatitis C virus polymerase selectively and inhibit its RNA synthesis from the natural viral RNA templates. Virology 20030315
Structure and function of an archaeal homolog of survival protein E (SurEalpha): an acid phosphatase with purine nucleotide specificity. Journal of molecular biology 20030307
Neuron-specific enolase, nucleotides, nucleosides, purine bases, oxypurines and uric acid concentrations in cerebrospinal fluid of children with meningitis. Brain & development 20030301
Novel antifolate drugs. Current oncology reports 20030301
Purine and deazapurine nucleosides: synthetic approaches, molecular modelling and biological activity. Farmaco (Societa chimica italiana : 1989) 20030301
2-Chlorodeoxyadenosine therapy for disseminated Langerhans cell histiocytosis. Mayo Clinic proceedings 20030301
The effect of lead ions on the energy metabolism of human erythrocytes in vitro. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030301
Mechanisms involved in the loss of excitatory post-stimulus responses by inflammation. Naunyn-Schmiedeberg's archives of pharmacology 20030301
Enhanced adenosine A(2B) mediated coronary response in reserpinised rat heart. Naunyn-Schmiedeberg's archives of pharmacology 20030301
[Colorectal cancer and folate]. Zeitschrift fur Gastroenterologie 20030301
Splenectomy and treatments of historical interest. Best practice & research. Clinical haematology 20030301
Interferon in the treatment of hairy-cell leukemia. Best practice & research. Clinical haematology 20030301
Pentostatin in the treatment of hairy-cell leukemia. Best practice & research. Clinical haematology 20030301
Cladribine in the treatment of hairy-cell leukaemia. Best practice & research. Clinical haematology 20030301
Immunobiological treatments of hairy-cell leukaemia. Best practice & research. Clinical haematology 20030301
Purine nucleoside analogues in the treatment of myleoid leukemias. Leukemia & lymphoma 20030301
Toxicity of nitrous oxide. Best practice & research. Clinical anaesthesiology 20030301
Synthesis of (Z)-(2,3-bis-hydroxymethyl)methylenecyclopropane analogues of purine nucleosides. Nucleosides, nucleotides & nucleic acids 20030301
Synthesis and flow cytometric evaluation of novel 1,2,3,4-tetrahydroisoquinoline conformationally constrained analogues of nitrobenzylmercaptopurine riboside (NBMPR) designed for probing its conformation when bound to the es nucleoside transporter. Journal of medicinal chemistry 20030227
Characterization of a mutant Bacillus subtilis adenylosuccinate lyase equivalent to a mutant enzyme found in human adenylosuccinate lyase deficiency: asparagine 276 plays an important structural role. Biochemistry 20030225
Survival with dacarbazine and fotemustine in newly diagnosed glioblastoma multiforme. British journal of cancer 20030224
Synthesis of purine- and pyrimidine-substituted heptadienes. The stereochemistry of cyclization and cyclopolymerization products. The Journal of organic chemistry 20030221
Rapid disappearance of deoxyribose-1-phosphate in platelet derived endothelial cell growth factor/thymidine phosphorylase overexpressing cells. Biochemical and biophysical research communications 20030214
The transthyretin-related protein family. European journal of biochemistry 20030201
8'-aminoguanosine inclusion results in enhanced efflux of taurine in preconditioned ischemic myocardium. Journal of cardiovascular pharmacology 20030201
Structure of bovine adenosine deaminase complexed with 6-hydroxy-1,6-dihydropurine riboside. Acta crystallographica. Section D, Biological crystallography 20030201
Simultaneous determination of purine nucleotides, their metabolites and beta-nicotinamide adenine dinucleotide in cerebellar granule cells by ion-pair high performance liquid chromatography. Brain research. Brain research protocols 20030201
Advances in the treatment of hairy-cell leukaemia. The Lancet. Oncology 20030201
Serum adenosine deaminase activity and its isoenzyme pattern in women with normal pregnancies. Archives of gynecology and obstetrics 20030201
Enantioselective binding of S- and R-ofloxacin to various synthetic polynucleotides. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20030201
[Cladribine]. Gan to kagaku ryoho. Cancer & chemotherapy 20030201
Significance of the non-oxidative route of the pentose phosphate pathway for supplying carbon to the purine-nucleotide pathway in Corynebacterium ammoniagenes. Journal of industrial microbiology & biotechnology 20030201
Sorting of rat SPNT in renal epithelium is independent of N-glycosylation. Pharmaceutical research 20030201
Alkaline hydrolysis of cladribine. Die Pharmazie 20030201
Diet and procedures used to detach particle-associated microbes from ruminal digesta influence chemical composition of microbes and estimation of microbial growth in Rusitec fermenters. Journal of animal science 20030201
[Pathophysiology, diagnosis and conservative therapy of non-calcium kidney calculi]. Therapeutische Umschau. Revue therapeutique 20030201
Relation between reticulocyte count and characteristics of erythrocyte 5'-nucleotidase in dogs, cats, cattle and humans. The Journal of veterinary medical science 20030201
Targeting bcl-2 by triplex-forming oligonucleotide--a promising carrier for gene-radiotherapy. Cancer biotherapy & radiopharmaceuticals 20030201
Involvement of gibberellin and cytokinin in the formation of embryogenic cell clumps in carrot (Daucus carota). Journal of plant physiology 20030201
Familial spastic paraplegia as the presenting manifestation in patients with purine nucleoside phosphorylase deficiency. Journal of child neurology 20030201
[Prognostic significance of serum uric acid in patients with chronic obstructive pulmonary disease receiving home oxygen therapy]. Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20030201
Synthesis and biological activities of 2-functionalized purine nucleosides. Nucleosides, nucleotides & nucleic acids 20030201
Synthesis of antisense oligonucleotides with minimum depurination. Nucleosides, nucleotides & nucleic acids 20030201
A new method for the synthesis of 2'-O-benzyladenosine using Mitsunobu reaction. Nucleosides, nucleotides & nucleic acids 20030201
A phase I clinical trial of spicamycin derivative KRN5500 (NSC 650426) using a phase I accelerated titration '2B' design. Investigational new drugs 20030201
[Reversible temperature dependence of surface-enhanced Raman scattering of adenine, purine and pyrene]. Guang pu xue yu guang pu fen xi = Guang pu 20030201
Electrospray ionisation mass spectrometry: principles and clinical applications. The Clinical biochemist. Reviews 20030201
Pressures in archaeal protein coding genes: a comparative study. Comparative and functional genomics 20030201
Binding of the priming nucleotide in the initiation of transcription by T7 RNA polymerase. The Journal of biological chemistry 20030131
Synthesis, anti-HIV activity, and molecular mechanism of drug resistance of L-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides. Journal of medicinal chemistry 20030130
Synthesis and biological activity of nitro heterocycles analogous to megazol, a trypanocidal lead. Journal of medicinal chemistry 20030130
Nucleic acid related compounds. 118. Nonaqueous diazotization of aminopurine derivatives. Convenient access to 6-halo- and 2,6-dihalopurine nucleosides and 2'-deoxynucleosides with acyl or silyl halides. The Journal of organic chemistry 20030124
[Chronic lymphocytic leukemia: high time for a risk-adapted approach]. Nederlands tijdschrift voor geneeskunde 20030118
Adenosine A1 receptors regulate the response of the mouse circadian clock to light. Brain research 20030117
Prodrugs of purine and pyrimidine analogues for the intestinal di/tri-peptide transporter PepT1: affinity for hPepT1 in Caco-2 cells, drug release in aqueous media and in vitro metabolism. Journal of controlled release : official journal of the Controlled Release Society 20030117
Disruption of the SHM2 gene, encoding one of two serine hydroxymethyltransferase isoenzymes, reduces the flux from glycine to serine in Ashbya gossypii. The Biochemical journal 20030115
Down-regulation of deoxycytidine kinase in human leukemic cell lines resistant to cladribine and clofarabine and increased ribonucleotide reductase activity contributes to fludarabine resistance. Biochemical pharmacology 20030115
Cytotoxicity and mode of action of vanada- and niobatricarbadecaboranyl monohalide complexes in human HL-60 promyelocytic leukemia cells. Journal of inorganic biochemistry 20030115
Copper(II) complexes with uridine, uridine 5'-monophosphate, spermidine, or spermine in aqueous solution. Journal of inorganic biochemistry 20030115
Intrinsic acid-base properties of purine derivatives in aqueous solution and comparison of the acidifying effects of platinum(II) coordinated to N1 or N7: acidifying effects are reciprocal and the proton 'outruns' divalent metal ions. Inorganic chemistry 20030113
Effect of a novel somatostatin analogue combined with cytotoxic drugs on human tumour xenografts and metastasis of B16 melanoma. British journal of cancer 20030113
Storage and release of ATP from astrocytes in culture. The Journal of biological chemistry 20030110
[Effect of morphine on expression of gene of enzymes related to purine nucleotide metabolism in c6 glioma]. Zhonghua yi xue za zhi 20030110
DNA adduct formation by the ubiquitous environmental pollutant 3-nitrobenzanthrone and its metabolites in rats. Biochemical and biophysical research communications 20030103
8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases. Journal of medicinal chemistry 20030102
New N-n-propyl-substituted 3-aryl- and 3-cyclohexylpiperidines as partial agonists at the D4 dopamine receptor. Journal of medicinal chemistry 20030102
Inosine reduces inflammation and improves survival in a murine model of colitis. American journal of physiology. Gastrointestinal and liver physiology 20030101
A three-enzyme microelectrode sensor for detecting purine release from central nervous system. Biosensors & bioelectronics 20030101
Triplex-forming oligonucleotides as modulators of gene expression. The international journal of biochemistry & cell biology 20030101
Influence of p53 and p21(WAF1) expression on sensitivity of cancer cells to cladribine. Biochemical pharmacology 20030101
The stm4066 gene product of Salmonella enterica serovar Typhimurium has aminoimidazole riboside (AIRs) kinase activity and allows AIRs to satisfy the thiamine requirement of pur mutant strains. Journal of bacteriology 20030101
Antitumor activity of 2-fluoro-2'-deoxyadenosine against tumors that express Escherichia coli purine nucleoside phosphorylase. Cancer gene therapy 20030101
Three 2-aminopurine derivatives. Acta crystallographica. Section C, Crystal structure communications 20030101
Cloning, overexpression, and purification of functional human purine nucleoside phosphorylase. Protein expression and purification 20030101
Algorithms for computing parsimonious evolutionary scenarios for genome evolution, the last universal common ancestor and dominance of horizontal gene transfer in the evolution of prokaryotes. BMC evolutionary biology 20030101
Application of pharmacokinetic/pharmacodynamic and stochastic modelling to 6-mercaptopurine micronucleus induction in mouse bone marrow erythrocytes. Journal of applied toxicology : JAT 20030101
Azathioprine and anti-TNF alpha therapies in Crohn's disease: a review of pharmacology, clinical efficacy and safety. Pharmacological research 20030101
Long-term outcome with pentostatin treatment in hairy cell leukemia patients. A French retrospective study of 238 patients. Leukemia 20030101
Microarray analysis of orthologous genes: conservation of the translational machinery across species at the sequence and expression level. Genome biology 20030101
Combination therapy in childhood leukaemia: in vitro studies of thiopurines and inhibitors of purine metabolism on apoptosis. Annals of clinical biochemistry 20030101
Marginal zone-related neoplasms of splenic and nodal origin. Haematologica 20030101
Sensitive and high-throughput analyses of purine metabolites by dynamic pH junction multiplexed capillary electrophoresis: a new tool for metabolomic studies. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030101
Analysis of purinergic and cholinergic fast synaptic transmission to identified myenteric neurons. Neuroscience 20030101
Viable nonsense mutants for the essential gene SUP45 of Saccharomyces cerevisiae. BMC molecular biology 20030101
Mass spectrometric investigation of N-sulfonylated purine nucleic bases and nucleosides. Rapid communications in mass spectrometry : RCM 20030101
Nonmyeloablative preparative regimens for allogeneic hematopoietic transplantation. Biology and current indications. Oncology (Williston Park, N.Y.) 20030101
[Changes in blood hormone levels in gout and methods of their correction (an experimental and clinical study)]. Klinicheskaia laboratornaia diagnostika 20030101
Feminizing chicks: a model for avian sex determination based on titration of Hint enzyme activity and the predicted structure of an Asw-Hint heterodimer. Genome biology 20030101
Fludarabine in combination with cyclophosphamide decreases incidence of GVHD and maintains effective graft-versus-leukemia effect after allogeneic stem cell transplantation in murine lymphocytic leukemia. Bone marrow transplantation 20030101
[Management of hyperuricemia in occupational health: with reference to 'guidelines for the management of hyperuricemia and gout']. Sangyo eiseigaku zasshi = Journal of occupational health 20030101
[Biosynthetic pathways for purine nucleotides and uric acid]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Phosphoribosylpyrophosphate(PRPP) synthetase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Amidophosphoribosyltransferase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[GAR synthetase . GAR transformylase . AIR synthetase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[FGAM synthetase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[AIR carboxylase . SAICAR synthetase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[The second half of de novo synthetic pathway of IMP and conversion of IMP to AMP]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[IMP dehydrogenase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[GMP synthetase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Hypoxanthine guanine phosphoribosyltransferase (HPRT)]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Adenine phosphoribosyltransferase (APRT)]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[5'-nucleotidase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Purine nucleoside phosphorylase (PNP)]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[AMP deaminase (AMPD)]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[GMP reductase]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Effect of foods on serum uric acid level]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Effect of ethanol on uric acid level]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Hyperuricemia--definition and classification]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Idiopathic hyperuricemia]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Diet therapy for management of hyperuricemia and gout]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Exercise therapy for hyperuricemia]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Hyperuricemia associated with inborn errors of purine metabolism: screening, enzymatic and genetic diagnosis]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[PRPP synthetase superactivity]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Non-drug substance (over intake of foods which are contained purine body, fat and fructose)]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Alcohol-related tissue injury and hyperuricemia]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Animal models for abnormal purine metabolism]. Nihon rinsho. Japanese journal of clinical medicine 20030101
[Contents of purine bases in foods and alcoholic beverages]. Nihon rinsho. Japanese journal of clinical medicine 20030101
Expression and localization of estrogen receptor-alpha protein in normal and abnormal term placentae and stimulation of trophoblast differentiation by estradiol. Reproductive biology and endocrinology : RB&E 20030101
Signaling and regulation of G protein-coupled receptors in airway smooth muscle. Respiratory research 20030101
Monitoring of protein profiles for the optimization of recombinant fermentation processes using public domain databases. Electrophoresis 20030101
5'-aminoimidazole-4-carboxamide riboside induces apoptosis in human neuroblastoma cells. Neuroscience 20030101
The evolution of Runx genes I. A comparative study of sequences from phylogenetically diverse model organisms. BMC evolutionary biology 20030101
Correlation of serum levels of adenosine deaminase activity and its isoenzymes with disease activity in rheumatoid arthritis. Clinical and experimental rheumatology 20030101
Cyclin-dependent kinase modulators studied at the NCI: pre-clinical and clinical studies. Current medicinal chemistry. Anti-cancer agents 20030101
[Significance of TPMT activity and TGNs level detection for individualizing 6-mercaptopurine chemotherapy]. Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20030101
Therapeutic efficacy and safety of 6-mercaptopurine and azathioprine in patients with Crohn's disease. Reviews in gastroenterological disorders 20030101
In AML cell lines Ara-C combined with purine analogues is able to exert synergistic as well as antagonistic effects on proliferation, apoptosis and disruption of mitochondrial membrane potential. Leukemia & lymphoma 20030101
The effect of cyclosporin A used alone and in combination with either 2-chlorodeoxyadenosine or fludarabine on normal and chronic myelogenous leukemia progenitors in vitro. Archivum immunologiae et therapiae experimentalis 20030101
Measurement of peroxisomal enzyme activities in the liver of brown trout (Salmo trutta), using spectrophotometric methods. BMC biochemistry 20030101
New directions in the diagnosis and treatment of chronic lymphocytic leukaemia. Drugs 20030101
Analysis and functional classification of transcripts from the nematode Meloidogyne incognita. Genome biology 20030101
[The role of enzymatic features of hypoxia in ulcers]. Likars'ka sprava 20030101
Wavelet to predict bacterial ori and ter: a tendency towards a physical balance. BMC genomics 20030101
The yeast ISN1 (YOR155c) gene encodes a new type of IMP-specific 5'-nucleotidase. BMC biochemistry 20030101
Comparison of the changes in global gene expression of Escherichia coli induced by four bactericidal agents. Journal of molecular microbiology and biotechnology 20030101
Potent P2Y6 receptor mediated contractions in human cerebral arteries. BMC pharmacology 20030101
Solid-phase synthesis of nucleoside analogues. Journal of combinatorial chemistry 20030101
Genome wide identification of regulatory motifs in Bacillus subtilis. BMC bioinformatics 20030101
Nucleosides and nucleotides. 218. Alternate-strand triple-helix formation by the 3'-3'-linked oligodeoxynucleotides using a purine motif. Bioconjugate chemistry 20030101
On heteroaromaticity of nucleobases. Bond lengths as multidimensional phenomena. Journal of chemical information and computer sciences 20030101
Rapid de-localization of actin leading edge components with BDM treatment. BMC cell biology 20030101
A national survey on the patterns of treatment of inflammatory bowel disease in Canada. BMC gastroenterology 20030101
Model building and model checking for biochemical processes. Cell biochemistry and biophysics 20030101
Horizontally transferred genes in plant-parasitic nematodes: a high-throughput genomic approach. Genome biology 20030101
Characterisation of methionine adenosyltransferase from Mycobacterium smegmatis and M. tuberculosis. BMC microbiology 20030101
Of mice and men: phylogenetic footprinting aids the discovery of regulatory elements. Journal of biology 20030101
Functional expression of a sodium dependent nucleoside transporter on rabbit cornea: Role in corneal permeation of acyclovir and idoxuridine. Current eye research 20030101
Internal correspondence analysis of codon and amino-acid usage in thermophilic bacteria. Journal of applied genetics 20030101
Relationships between hemodynamic parameters and myocardial energy and antioxidant status in heart transplantation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20030101
Wegener's granulomatosis: current and upcoming therapies. Arthritis research & therapy 20030101
Highly efficient lentiviral gene transfer in CD34+ and CD34+/38-/lin- cells from mobilized peripheral blood after cytokine prestimulation. Stem cells (Dayton, Ohio) 20030101
Inosine protects against the development of diabetes in multiple-low-dose streptozotocin and nonobese diabetic mouse models of type 1 diabetes. Molecular medicine (Cambridge, Mass.) 20030101
Management of advanced chronic lymphocytic leukemia. Current hematology reports 20030101
Comparative genomics of Archaea: how much have we learned in six years, and what's next? Genome biology 20030101
[Arterial hypertension, its metabolic aspects and kidney function in patients after hemorrhagic fever with renal syndrome]. Terapevticheskii arkhiv 20030101
Exploring the molecular basis of selectivity in A1 adenosine receptors agonists: a case study. Journal of computer-aided molecular design 20030101
The fragile X mental retardation protein binds and regulates a novel class of mRNAs containing U rich target sequences. Neuroscience 20030101
Antioxidant intake, plasma antioxidants and oxidative stress in a randomized, controlled, parallel, Mediterranean dietary intervention study on patients with rheumatoid arthritis. Nutrition journal 20030101
Pharmacokinetics and degree of aromatization rather than total dose of different preparations determine the effects of testosterone: a nonhuman primate study in Macaca fascicularis. Journal of andrology 20030101
Increased retention of functional fusions to toxic genes in new two-hybrid libraries of the E. coli strain MG1655 and B. subtilis strain 168 genomes, prepared without passaging through E. coli. BMC genomics 20030101
Conjugates of PNA with naphthalene diimide derivatives having a broad range of DNA affinities. Bioconjugate chemistry 20030101
Relationship of SARS-CoV to other pathogenic RNA viruses explored by tetranucleotide usage profiling. BMC bioinformatics 20030101
Synthesis of apio analogues of neplanocin A as potential inhibitors of S-adenosylhomocysteine hydrolase. Nucleic acids research. Supplement (2001) 20030101
The NMR studies of substituent effects on the N-H...N hydrogen bond in duplex DNA using 2'-deoxynebularine and 15N labeled 5-substituted-2'-deoxyuridine base pairs. Nucleic acids research. Supplement (2001) 20030101
Synthesis and biological properties of stable phosmidosine analogs. Nucleic acids research. Supplement (2001) 20030101
Transition state analogues for enzymes of nucleic acid metabolism. Nucleic acids research. Supplement (2001) 20030101
Thermodynamic analyses of purine motif triplex DNA formation. Nucleic acids research. Supplement (2001) 20030101
Utilization efficiency of the oxidized purine nucleotide analogs by DNA polymerase eta. Nucleic acids research. Supplement (2001) 20030101
Influence of glucose in dialyzing fluid on purine concentrations in hemodialyzed patients with chronic renal failure. Nephron. Clinical practice 20030101
Oral fludarabine. Drugs 20030101
Strategies in the design of prodrugs of anti-HIV agents. Current topics in medicinal chemistry 20030101
Anticancer antifolates: current status and future directions. Current pharmaceutical design 20030101
Thioguanine, mercaptopurine: their analogs and nucleosides as antimetabolites. Current pharmaceutical design 20030101
Trustworthiness and metrics in visualizing similarity of gene expression. BMC bioinformatics 20030101
An industrial process for synthesizing Lodenosine (FddA). Nucleosides, nucleotides & nucleic acids 20030101
4'-C-methyl-beta-D-ribofuranosyl purine and pyrimidine nucleosides revisited. Nucleosides, nucleotides & nucleic acids 20030101
Synthetic studies on guanofosfocin: glycosylation of 8-oxo-purine nucleosides via Mitsunobu reaction. Nucleosides, nucleotides & nucleic acids 20030101
Selective metalation of 6-methylpurines: synthesis of 6-fluoromethylpurines and related nucleosides. Nucleosides, nucleotides & nucleic acids 20030101
Chemo-enzymatic synthesis of 3-deoxy-beta-D-ribofuranosyl purines and study of their biological properties. Nucleosides, nucleotides & nucleic acids 20030101
Introduction of a benzyl group onto the 2'-OH of 6-chloropurine 3'-O-benzoylriboside. Nucleosides, nucleotides & nucleic acids 20030101
Purine derivatives of 1,2-disubstituted cyclohexane analogues of nucleosides. Nucleosides, nucleotides & nucleic acids 20030101
Synthesis of 4'-C-ethynyl and 4'-C-cyano purine nucleosides from natural nucleosides and their anti-HIV activity. Nucleosides, nucleotides & nucleic acids 20030101
Synthesis of modified RNA-oligonucleotides for structural investigations. Nucleosides, nucleotides & nucleic acids 20030101
Oligonucleotides incorporating N7-(2'-deoxy-beta-D-erythro-pentofuranosyl)isoguanine. Nucleosides, nucleotides & nucleic acids 20030101
5'-O-fluorosulfonylbenzoyl esters of purine nucleosides as potential inhibitors of NTPase/helicase and polymerase of Flaviviridae viruses. Nucleosides, nucleotides & nucleic acids 20030101
Recognition of cyclonucleoside lesions by the Lactococcus lactis FPG protein. Nucleosides, nucleotides & nucleic acids 20030101
Interactions of potent multisubstrate analogue inhibitors with purine nucleoside phosphorylase from calf spleen--kinetic and spectrofluorimetric studies. Nucleosides, nucleotides & nucleic acids 20030101
Synthesis and antitumor activity of N-sulfonyl derivatives of nucleobases and sulfonamido nucleoside derivatives. Nucleosides, nucleotides & nucleic acids 20030101
Synthesis of 2-deoxy-beta-D-ribose 1-phosphate, NMR comparison and its enzymatic activity for structural elucidation of synthetic alpha-isomer. Nucleosides, nucleotides & nucleic acids 20030101
Interactions of trimeric purine nucleoside phosphorylases with ground state analogues--calorimetric and fluorimetric studies. Nucleosides, nucleotides & nucleic acids 20030101
Crystal structure of calf spleen purine nucleoside phosphorylase in a complex with multisubstrate analogue inhibitor with 2,6-diaminopurine aglycone. Nucleosides, nucleotides & nucleic acids 20030101
[Activity of purine enzyme metabolism in rat thymocytes after irradiation and after administration of riboxine]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20030101
Molecular characterization of the zebrafish P2X receptor subunit gene family. Neuroscience 20030101
In vitro studies on DNA-photosensitization by different drug stereoisomers. Toxicology in vitro : an international journal published in association with BIBRA 20030101
Multi-level response of the yeast genome to glucose. Genome biology 20030101
[Diet therapy in combined disorders of purine and lipid metabolism in children]. Voprosy pitaniia 20030101
Hydrolytic cleavage of purine ribonucleosides in Aspergillus phoenicis. Journal of basic microbiology 20030101
Infections in patients with hematological cancer: recent developments. Hematology. American Society of Hematology. Education Program 20030101
Azathioprine as a treatment for severe atopic eczema in children with a partial thiopurine methyl transferase (TPMT) deficiency. Pediatric dermatology 20030101
Systemic chemotherapy for the treatment of mycosis fungoides and Sézary syndrome. Dermatologic therapy 20030101
Mycophenolate mofetil inhibits the development of Coxsackie B3-virus-induced myocarditis in mice. BMC microbiology 20030101
The tyranny of adenosine recognition among RNA aptamers to coenzyme A. BMC evolutionary biology 20030101
Current data with pemetrexed (Alimta) in non-small-cell lung cancer. Clinical lung cancer 20030101
Guanosine deaminase in human serum and tissue extracts--a reappraisal of the products. British journal of biomedical science 20030101
Identification of malignant brain edema after hemispheric stroke by PET-imaging and microdialysis. Acta neurochirurgica. Supplement 20030101
Plasticity of purine release during cerebral ischemia: clinical implications? Journal of cellular and molecular medicine 20030101
Cellular issues relating to the resistance of HIV to antiretroviral agents. Scandinavian journal of infectious diseases. Supplementum 20030101
Short pyrimidine stretches containing mixed base PNAs are versatile tools to induce translation elongation arrest and truncated protein synthesis. Oligonucleotides 20030101
Cloning, expression, activity and folding studies of serine hydroxymethyltransferase: a target enzyme for cancer chemotherapy. Journal of molecular microbiology and biotechnology 20030101
Cardiovascular drugs and serum uric acid. Cardiovascular drugs and therapy 20030101
Comparison of responses by bacteriophages and bacteria to pressures on the base composition of open reading frames. Applied bioinformatics 20030101
Levels of purine, kynurenine and lipid peroxidation products in patients with inflammatory bowel disease. Advances in experimental medicine and biology 20030101
[The influence of some trace elements on bioaccumulation in tissues and bioenergetic metabolism of the edible snail Helix aspersa maxima as determined by HPLC of purine derivatives]. Annales Academiae Medicae Stetinensis 20030101
New approaches to the treatment of overactive bladder: the purine pathways and an update on the tension-free vaginal tape sling. Reviews in urology 20030101
Treatment of cutaneous T-cell lymphomas with purine analogues (fludarabine and 2-chlorodeoxyadenosine). Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20030101
Structural insights into the avian AICAR transformylase mechanism. Biochemistry 20021231
2.4-A crystal structure of the asymmetric platinum complex [Pt(ammine)(cyclohexylamine)]2+ bound to a dodecamer DNA duplex. The Journal of biological chemistry 20021220
Molecular recognition in purine-rich internal loops: thermodynamic, structural, and dynamic consequences of purine for adenine substitutions in 5'(rGGCAAGCCU)2. Biochemistry 20021217
The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland. Genes & development 20021215
A potent and highly selective sulfotransferase inhibitor. Journal of the American Chemical Society 20021211
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase. Biochemistry 20021210
Diagnosis and monitoring of inborn errors of metabolism using urease-pretreatment of urine, isotope dilution, and gas chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021205
The diagnosis and treatment of hairy-cell leukaemia. Blood reviews 20021201
Purine enzymes in patients with rheumatoid arthritis treated with methotrexate. Annals of the rheumatic diseases 20021201
Discovery of novel targets of quinoline drugs in the human purine binding proteome. Molecular pharmacology 20021201
Adduction of catechol estrogens to nucleosides. Steroids 20021201
Functional regulation of xanthine oxidoreductase expression and localization in the mouse mammary gland: evidence of a role in lipid secretion. The Journal of physiology 20021201
Induction of COX-2 and reactive gliosis by P2Y receptors in rat cortical astrocytes is dependent on ERK1/2 but independent of calcium signalling. Journal of neurochemistry 20021201
Atmospheric pressure ionization mass spectrometry of purine and pyrimidine markers of inherited metabolic disorders. Journal of mass spectrometry : JMS 20021201
Sequence-dependent dynamics of duplex DNA: the applicability of a dinucleotide model. Biophysical journal 20021201
Cardiac surgery: myocardial energy balance, antioxidant status and endothelial function after ischemia-reperfusion. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20021201
The chloroplast import receptor Toc34 functions as preprotein-regulated GTPase. Biological chemistry 20021201
Molecular, biochemical, and cellular pharmacology of pemetrexed. Seminars in oncology 20021201
Are activation markers (CD25, CD38 and CD103) predictive of sensitivity to purine analogues in patients with T-cell prolymphocytic leukemia and other lymphoproliferative disorders? Leukemia & lymphoma 20021201
Regulation of expression of the Rhizopus oryzae uricase and urease enzymes. Canadian journal of microbiology 20021201
Modeling the transmembrane arrangement of the uncoupling protein UCP1 and topological considerations of the nucleotide-binding site. Journal of bioenergetics and biomembranes 20021201
The trapping of a spontaneously 'flipped-out' base from double helical nucleic acids by host-guest complexation with beta-cyclodextrin: the intrinsic base-flipping rate constant for DNA and RNA. Journal of the American Chemical Society 20021127
Amino acid substitution of arginine 80 in 17beta-hydroxysteroid dehydrogenase type 3 and its effect on NADPH cofactor binding and oxidation/reduction kinetics. Biochimica et biophysica acta 20021119
Concentrative nucleoside transporter (rCNT1) is targeted to the apical membrane through the hepatic transcytotic pathway. Experimental cell research 20021115
Intrinsic lifetimes of the excited state of DNA and RNA bases. Journal of the American Chemical Society 20021106
DNA oligonucleotide duplexes containing intramolecular platinated cross-links: energetics, hydration, sequence, and ionic effects. Biopolymers 20021105
Specific, sensitive and accurate liquid chromatographic-tandem mass spectrometric method for the measurement of ribavirin in rat and monkey plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021105
2-Aminopurine electronic structure and fluorescence properties in DNA. Biochemistry 20021105
Hydroxamate based inhibitors of adenylyl cyclase. Part 1: the effect of acyclic linkers on P-site binding. Bioorganic & medicinal chemistry letters 20021104
Hydroxamate based inhibitors of adenylyl cyclase. Part 2: the effect of cyclic linkers on P-site binding. Bioorganic & medicinal chemistry letters 20021104
Cladribine induces immunophenotypical changes in bone marrow mast cells from mastocytosis. Report of a case of mastocytosis associated with a lymphoplasmacytic lymphoma. Leukemia research 20021101
The activities of serum adenosine deaminase and xanthine oxidase enzymes in Behcet's disease. Clinica chimica acta; international journal of clinical chemistry 20021101
Purine nucleoside phosphorylase: a fortuitous cytosolic arsenate reductase? Toxicological sciences : an official journal of the Society of Toxicology 20021101
Reduction of arsenate to arsenite in hepatic cytosol. Toxicological sciences : an official journal of the Society of Toxicology 20021101
Purine nucleoside phosphorylase as a cytosolic arsenate reductase. Toxicological sciences : an official journal of the Society of Toxicology 20021101
Determination of platinated purines in oligoribonucleotides by limited digestion with ribonucleases T1 and U2. Analytical biochemistry 20021101
Cellular background level of 8-oxo-7,8-dihydro-2'-deoxyguanosine: an isotope based method to evaluate artefactual oxidation of DNA during its extraction and subsequent work-up. Carcinogenesis 20021101
Comparison of peptides in the phloem sap of flowering and non-flowering Perilla and lupine plants using microbore HPLC followed by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Planta 20021101
[Treatment of Lesch-Nyhan syndrome]. Revista de neurologia 20021101
Inhibitors of de novo nucleotide biosynthesis as drugs. Accounts of chemical research 20021101
Proteomic evaluation of intermediary metabolism enzyme proteins in fetal Down's syndrome cerebral cortex. Proteomics 20021101
Inosine modulates gut barrier dysfunction and end organ damage in a model of ischemia-reperfusion injury. The Journal of surgical research 20021101
High rates of long-lasting remissions after 5-day bendamustine chemotherapy cycles in pre-treated low-grade non-Hodgkin's-lymphomas. Journal of cancer research and clinical oncology 20021101
Incorporation of the anticancer agent KRN5500 into polymeric micelles diminishes the pulmonary toxicity. Japanese journal of cancer research : Gann 20021101
The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system. Autonomic neuroscience : basic & clinical 20021031
Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase. The Journal of biological chemistry 20021025
Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides. Journal of medicinal chemistry 20021024
Reaction mechanism of the HGXPRTase from Plasmodium falciparum: a hybrid potential quantum mechanical/molecular mechanical study. Journal of the American Chemical Society 20021023
[Uncommon purine lithiasis: adenine phosphoribosyltransferase (APRT) deficiency and hereditary xanthinuria]. Medicina clinica 20021019
The adenine phosphoribosyltransferase from Giardia lamblia has a unique reaction mechanism and unusual substrate binding properties. The Journal of biological chemistry 20021018
Cutting edge: CATERPILLER: a large family of mammalian genes containing CARD, pyrin, nucleotide-binding, and leucine-rich repeat domains. Journal of immunology (Baltimore, Md. : 1950) 20021015
A colorimetric 96-well microtiter plate assay for the determination of urate oxidase activity and its kinetic parameters. Analytical biochemistry 20021015
The crystal structure of eosinophil cationic protein in complex with 2',5'-ADP at 2.0 A resolution reveals the details of the ribonucleolytic active site. Biochemistry 20021008
Simultaneous expression of hCNT1-CFP and hENT1-YFP in Madin-Darby canine kidney cells. Localization and vectorial transport studies. The Journal of biological chemistry 20021004
Mutations in the pho2 (bas2) transcription factor that differentially affect activation with its partner proteins bas1, pho4, and swi5. The Journal of biological chemistry 20021004
Ring-expanded ('Fat') nucleosides as broad-spectrum anticancer and antiviral agents. Current topics in medicinal chemistry 20021001
Simple non-radiochemical HPLC-linked method for screening for purine metabolism disorders using dried blood spot. Clinica chimica acta; international journal of clinical chemistry 20021001
Modulation of hippocampal glutamatergic transmission by ATP is dependent on adenosine a(1) receptors. The Journal of pharmacology and experimental therapeutics 20021001
Dynamics and binding modes of free cdk2 and its two complexes with inhibitors studied by computer simulations. Journal of biomolecular structure & dynamics 20021001
Transfusion-associated graft-versus-host disease in a patient with Waldenstrom's macroglobulinaemia. Vox sanguinis 20021001
Effect of beer on the plasma concentrations of uridine and purine bases. Metabolism: clinical and experimental 20021001
Genome-wide identification of nodule-specific transcripts in the model legume Medicago truncatula. Plant physiology 20021001
Development of a melanoma-specific adenovirus. Molecular therapy : the journal of the American Society of Gene Therapy 20021001
Differences between rat primary cortical neurons and astrocytes in purine release evoked by ischemic conditions. Neuropharmacology 20021001
Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency. Human genetics 20021001
Synthesis and fluorescence study of 7-azaindole in DNA oligonucleotides replacing a purine base. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20021001
Sequencing of 16S rRNA gene: a rapid tool for identification of Bacillus anthracis. Emerging infectious diseases 20021001
PSF and p54nrb bind a conserved stem in U5 snRNA. RNA (New York, N.Y.) 20021001
Chiral discrimination in platinum anticancer drugs. Environmental health perspectives 20021001
Advances in gene therapy for ADA-deficient SCID. Current opinion in molecular therapeutics 20021001
Purine nucleoside phosphorylase deficiency: a new case report and identification of two novel mutations (Gly156A1a and Val217Ile), only one of which (Gly156A1a) is deleterious. Clinical immunology (Orlando, Fla.) 20021001
Plasma 5'-nucleotidase activities increase in women with hyperemesis gravidarum. Clinical biochemistry 20021001
Synthesis and photophysics of purine-capped Q-CdS nanocrystallites. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20021001
The identification of five genetic loci of Francisella novicida associated with intracellular growth. FEMS microbiology letters 20020924
A parity code interpretation of nucleotide alphabet composition. Chemical communications (Cambridge, England) 20020921
An efficient and large-scale enantioselective synthesis of PNP405: a purine nucleoside phosphorylase inhibitor. The Journal of organic chemistry 20020920
Nucleic acid related compounds. 116. Nonaqueous diazotization of aminopurine nucleosides. Mechanistic considerations and efficient procedures with tert-butyl nitrite or sodium nitrite. The Journal of organic chemistry 20020920
A new concept for the preparation of beta-L- and beta-D-2',3'-dideoxynucleoside analogues. Organic letters 20020919
Structure and function of xanthine oxidoreductase: where are we now? Free radical biology & medicine 20020915
Antifolates targeting purine synthesis allow entry of tumor cells into S phase regardless of p53 function. Cancer research 20020915
A water-soluble synthetic spicamycin derivative (San-Gly) decreases mechanical allodynia in a rodent model of neuropathic pain. Neuroscience letters 20020913
Purine and pyrimidine (P2) receptors as drug targets. Journal of medicinal chemistry 20020912
Acyclic nucleoside analogues as novel inhibitors of human mitochondrial thymidine kinase. Journal of medicinal chemistry 20020912
Three-bond sugar-base couplings in purine versus pyrimidine nucleosides: a DFT study of Karplus relationships for (3)J(C2/4-H1') and (3)J(C6/8-H1') in DNA. Journal of the American Chemical Society 20020911
Oxidative DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine). Bioorganic & medicinal chemistry letters 20020902
Nucleotide binding to human uncoupling protein-2 refolded from bacterial inclusion bodies. The Biochemical journal 20020901
Adenine and deazaadenine nucleoside and deoxynucleoside analogues: inhibition of viral replication of sheep MVV (in vitro model for HIV) and bovine BHV-1. Bioorganic & medicinal chemistry 20020901
Peripheral T-cell lymphoma. Current oncology reports 20020901
Waldenström's macroglobulinaemia. Blood reviews 20020901
Pronounced cytostatic activity and bystander effect of a novel series of fluorescent tricyclic acyclovir and ganciclovir derivatives in herpes simplex virus thymidine kinase gene-transduced tumor cell lines. Gene therapy 20020901
Recent advances in cyclin-dependent kinase inhibition. Purine-based derivatives as anti-cancer agents. Roles and perspectives for the future. Current topics in medicinal chemistry 20020901
The contractile potency of adenosine triphosphate and ecto-adenosine triphosphatase activity in guinea pig detrusor and detrusor from patients with a stable, unstable or obstructed bladder. The Journal of urology 20020901
Inhibitory activity of dioxolane purine analogs on wild-type and lamivudine-resistant mutants of hepadnaviruses. Hepatology (Baltimore, Md.) 20020901
Chemotherapy targeting methylthioadenosine phosphorylase (MTAP) deficiency in adult T cell leukemia (ATL). Leukemia 20020901
Progress toward virtual screening for drug side effects. Proteins 20020901
Toward a description of the sialome of the adult female mosquito Aedes aegypti. Insect biochemistry and molecular biology 20020901
Cytotoxic effect of cyclosporin A alone and in combination with 2-chlorodeoxyadenosine against P388 murine leukemia in vivo. Medical science monitor : international medical journal of experimental and clinical research 20020901
Frequent occurrence of the T-loop RNA folding motif in ribosomal RNAs. RNA (New York, N.Y.) 20020901
Nucleosides are efficiently absorbed by Na(+)-dependent transport across the intestinal brush border membrane in veal calves. Journal of dairy science 20020901
Eosinophilic pneumonia after administration of fludarabine for the treatment of non-Hodgkin's lymphoma. Annals of hematology 20020901
[Purine regulon of gamma-proteobacteria: a detailed description]. Genetika 20020901
Photoionization of DNA and RNA bases, nucleosides and nucleotides through a combination of one- and two-photon pathways upon 266 nm nanosecond laser excitation. Photochemistry and photobiology 20020901
Non-Hodgkin's lymphoma: the evolving role of purine analogues. Best practice & research. Clinical haematology 20020901
Differentiation of human myeloid leukemia cells by plant redifferentiation-inducing hormones. Leukemia & lymphoma 20020901
Results of first salvage therapy for patients refractory to a fludarabine regimen in chronic lymphocytic leukemia. Leukemia & lymphoma 20020901
The cryptic adenine deaminase gene of Escherichia coli. Silencing by the nucleoid-associated DNA-binding protein, H-NS, and activation by insertion elements. The Journal of biological chemistry 20020830
Phosphorylation of pyrimidine L-deoxynucleoside analog diphosphates. Kinetics of phosphorylation and dephosphorylation of nucleoside analog diphosphates and triphosphates by 3-phosphoglycerate kinase. The Journal of biological chemistry 20020830
Long-patch base excision repair of apurinic/apyrimidinic site DNA is decreased in mouse embryonic fibroblast cell lines treated with plumbagin: involvement of cyclin-dependent kinase inhibitor p21Waf-1/Cip-1. Oncogene 20020829
Evaluation of rat liver apoptotic and necrotic cell death after cold storage using UW, HTK, and Celsior. Transplantation 20020827
Enantioselective synthesis of bicyclo[3.1.0]hexane carbocyclic nucleosides via a lipase-catalyzed asymmetric acetylation. Characterization of an unusual acetal byproduct. The Journal of organic chemistry 20020823
The purine nucleoside phosphorylase from Trichomonas vaginalis is a homologue of the bacterial enzyme. Biochemistry 20020820
Thermodynamic parameters for an expanded nearest-neighbor model for the formation of RNA duplexes with single nucleotide bulges. Biochemistry 20020820
Misalignment-mediated DNA polymerase beta mutations: comparison of microsatellite and frame-shift error rates using a forward mutation assay. Biochemistry 20020820
Severe pyridine nucleotide depletion in fibroblasts from Lesch-Nyhan patients. The Biochemical journal 20020815
Distinct interactions of G(salpha-long), G(salpha-short), and G(alphaolf) with GTP, ITP, and XTP. Biochemical pharmacology 20020815
Lipoyl dehydrogenase catalyzes reduction of nitrated DNA and protein adducts using dihydrolipoic acid or ubiquinol as the cofactor. Chemico-biological interactions 20020815
Perspectives on analyses of nucleic acid constituents: the basis of genomics. Journal of chromatography. A 20020802
Is the anomeric effect an important factor in the rate of adenosine deaminase catalyzed hydrolysis of purine nucleosides? A direct comparison of nucleoside analogues constructed on ribose and carbocyclic templates with equivalent heterocyclic bases selected to promote hydration. Bioorganic & medicinal chemistry 20020801
10-Formyl-5,10-dideaza-acyclic-5,6,7,8-tetrahydrofolic acid (10-formyl-DDACTHF): a potent cytotoxic agent acting by selective inhibition of human GAR Tfase and the de novo purine biosynthetic pathway. Bioorganic & medicinal chemistry 20020801
Atypical 5' splice sites cause CFTR exon 9 to be vulnerable to skipping. American journal of human genetics 20020801
Specificity of human and rat orthologs of the concentrative nucleoside transporter, SPNT. American journal of physiology. Renal physiology 20020801
Differential changes in purine nucleotides after Doxorubicin treatment of human cancer cells in vitro. International journal of oncology 20020801
The necessity of combining genomic and enzymatic data to infer metabolic function and pathways in the smallest bacteria: amino acid, purine and pyrimidine metabolism in Mollicutes. Frontiers in bioscience : a journal and virtual library 20020801
Molecular dynamics simulation study of DNA triplex formed by mixed sequences in solution. Journal of biomolecular structure & dynamics 20020801
Anti-angiogenic activity of the purine analog 6-thioguanine. Leukemia 20020801
Synthetic inhibitors of CDKs induce different responses in androgen sensitive and androgen insensitive prostatic cancer cell lines. Molecular pathology : MP 20020801
Molybdoenzymes and molybdenum cofactor in plants. Journal of experimental botany 20020801
Corticosteroid responsive fludarabine pulmonary toxicity. American journal of clinical oncology 20020801
Structural heterogeneity of pyrimidine/purine-biased DNA sequence analyzed by atomic force microscopy. European journal of biochemistry 20020801
Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer. Cancer research 20020801
Metabolism and mechanisms of action of bendamustine: rationales for combination therapies. Seminars in oncology 20020801
Bendamustine in the treatment of chronic lymphocytic leukemia: results and future perspectives. Seminars in oncology 20020801
Cold blood versus cold crystalloid cardioplegia for repair of ventricular septal defects in pediatric heart surgery: a randomized controlled trial. The Annals of thoracic surgery 20020801
On-line fourier transform infrared detection in capillary electrophoresis. Analytical chemistry 20020801
Permeability of Coxiella burnetii to ribonucleosides. Microbiology (Reading, England) 20020801
Xanthosine and xanthine. Substrate properties with purine nucleoside phosphorylases, and relevance to other enzyme systems. European journal of biochemistry 20020801
Ferritin and desferrioxamine attenuate xanthine oxidase-dependent leak in isolated perfused rat lungs. Inflammation 20020801
Normal transcription of the C1 inhibitor gene is dependent upon a polypurine-polypyrimidine region within the promoter. Inflammation 20020801
Substrate recognition by a family of uracil-DNA glycosylases: UNG, MUG, and TDG. Chemical research in toxicology 20020801
Pericardial concentrations of adenosine, inosine and hypoxanthine in an experimental canine model of spastic ischaemia. Clinical science (London, England : 1979) 20020801
Endothelin-1-induced elevations in purine metabolite concentrations -- autoregulatory protection in the canine pericardium? Clinical science (London, England : 1979) 20020801
Influence of moderate drinking on purine and carbohydrate metabolism. Alcoholism, clinical and experimental research 20020801
Sulfinosine-induced cell growth inhibition and apoptosis in human lung carcinomas in vitro. Investigational new drugs 20020801
Structure-activity analysis of the purine binding site of human liver glycogen phosphorylase. Chemistry & biology 20020801
Effects of forage particle size and grain fermentability in midlactation cows. I. Milk production and diet digestibility. Journal of dairy science 20020801
Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia. Molecular and cellular biochemistry 20020801
Screening for adenylosuccinate lyase deficiency: clinical, biochemical and molecular findings in four patients. Neuropediatrics 20020801
Purine metabolizing capability of Enterobacter agglomerans affects volatiles production and attractiveness to Mexican fruit fly. Journal of chemical ecology 20020801
Waldenström's macroglobulinemia: a review of therapy. Leukemia & lymphoma 20020801
Montmorillonite catalysis of 30-50 mer oligonucleotides: laboratory demonstration of potential steps in the origin of the RNA world. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20020801
Purine metabolism in leukocytes and erythrocytes in Graves' or Hashimoto's disease. Endocrine research 20020801
Studies on the thermal decomposition process and kinetics of purine drugs. Yao xue xue bao = Acta pharmaceutica Sinica 20020801
Computer simulations of trypanosomal nucleoside hydrolase: determination of the protonation state of the bound transition-state analogue. Journal of the American Chemical Society 20020731
Identification of the dITP- and XTP-hydrolyzing protein from Escherichia coli. Journal of biochemistry and molecular biology 20020731
Cloning, characterization and preliminary crystallographic analysis of Leishmania hypoxanthine-guanine phosphoribosyltransferase. Biochimica et biophysica acta 20020729
Functional importance of nucleotide identities within the pea atp9 mitochondrial promoter sequence. Journal of molecular biology 20020726
Substrate specificity and sequence preference of G:T mismatch repair: incision at G:T, O6-methylguanine:T, and G:U mispairs in DNA by human cell extracts. Biochemistry 20020723
Different substrate recognition motifs of human and trypanosome nucleobase transporters. Selective uptake of purine antimetabolites. The Journal of biological chemistry 20020719
Development of transition state analogues of purine nucleoside phosphorylase as anti-T-cell agents. Biochimica et biophysica acta 20020718
Targeting the cell cycle for cancer therapy. British journal of cancer 20020715
Targeted strand scission of DNA substrates by a tricopper(II) coordination complex. Journal of the American Chemical Society 20020710
Bistranded oxidized purine damage clusters: induced in DNA by long-wavelength ultraviolet (290-400 nm) radiation? Biochemistry 20020709
Importance of phosphate contacts for sequence recognition by EcoRI restriction enzyme. Biochemical and biophysical research communications 20020705
Current progress in suicide gene therapy for cancer. World journal of surgery 20020701
Mutation of a nuclear respiratory factor 2 binding site in the 5' untranslated region of the ADSL gene in three patients with adenylosuccinate lyase deficiency. American journal of human genetics 20020701
An ancient prevertebrate Na+-nucleoside cotransporter (hfCNT) from the Pacific hagfish (Eptatretus stouti). American journal of physiology. Cell physiology 20020701
The effect of thiopurine methyltransferase expression on sensitivity to thiopurine drugs. Molecular pharmacology 20020701
Effects of angiotensin II infusion on renal excretion of purine bases and oxypurinol. Metabolism: clinical and experimental 20020701
The physiology of endothelial xanthine oxidase: from urate catabolism to reperfusion injury to inflammatory signal transduction. Microcirculation (New York, N.Y. : 1994) 20020701
The mRNA structure has potent regulatory effects on type 2 iodothyronine deiodinase expression. Molecular endocrinology (Baltimore, Md.) 20020701
Center for Synchrotron Biosciences' U2B beamline: an international resource for biological infrared spectroscopy. Journal of synchrotron radiation 20020701
Adenosine and purine nucleosides protect rat primary astrocytes from peroxynitrite-potentiated, glucose deprivation-induced death: preservation of intracellular ATP level. Experimental neurology 20020701
Erythrocyte thiopurine methyl transferase assessment prior to azathioprine use in the UK. QJM : monthly journal of the Association of Physicians 20020701
Evolving concepts on the value of adenosine hyperresponsiveness in asthma and chronic obstructive pulmonary disease. Thorax 20020701
Impact of stem cell source and conditioning regimen on erythrocyte recovery kinetics after allogeneic haematopoietic stem cell transplantation from an ABO-incompatible donor. British journal of haematology 20020701
Aristolochic acid as a probable human cancer hazard in herbal remedies: a review. Mutagenesis 20020701
Multiple pulmonary nodules: an unusual presentation of fludarabine pulmonary toxicity: case report and review of literature. American journal of hematology 20020701
Synthesis of analogs of L-valacyclovir and determination of their substrate activity for the oligopeptide transporter in Caco-2 cells. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020701
Exposure-disease continuum for 2-chloro-2'-deoxyadenosine (2-CdA), a prototype teratogen: induction of lumbar hernia in the rat and species comparison for the teratogenic responses. Teratology 20020701
Symptomatic hypoglycemia in children receiving oral purine analogues for treatment of childhood acute lymphoblastic leukemia. Medical and pediatric oncology 20020701
Nucleoside analogues and nucleobases in cancer treatment. The Lancet. Oncology 20020701
Bias of purine stretches in sequenced chromosomes. Computers & chemistry 20020701
Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro. Anti-cancer drugs 20020701
PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site. The Journal of biological chemistry 20020628
Structure of a beta-alanine-linked polyamide bound to a full helical turn of purine tract DNA in the 1:1 motif. Journal of molecular biology 20020628
Oxidative damage and cytogenetic analysis in leukocytes of Parkinson's disease patients. Neurology 20020625
Hepatic amino acid-dependent signaling is under the control of AMP-dependent protein kinase. FEBS letters 20020619
A point mutation at the subunit interface of hypoxanthine-guanine-xanthine phosphoribosyltransferase impairs activity: role of oligomerization in catalysis. FEBS letters 20020619
A novel uracil-DNA glycosylase with broad substrate specificity and an unusual active site. The EMBO journal 20020617
[Experience with fludarabine treatment and review of the literature]. Orvosi hetilap 20020616
Six related nucleoside/nucleobase transporters from Trypanosoma brucei exhibit distinct biochemical functions. The Journal of biological chemistry 20020614
Cloning and characterization of methenyltetrahydrofolate synthetase from Saccharomyces cerevisiae. The Journal of biological chemistry 20020607
Roscovitine inhibits ongoing DNA synthesis in human cervical cancer. Cancer letters 20020606
Determination of acyclovir in maternal plasma, amniotic fluid, fetal and placental tissues by high-performance liquid chromatography. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605
Chemical composition and flavor of ecuadorian cocoa liquor. Journal of agricultural and food chemistry 20020605
Development of photo-crosslinking reagents for protein kinase-substrate interactions. FEBS letters 20020605
9-[(Hydroxymethyl)phenyl]adenines: new aryladenine substrates of adenosine deaminase. Bioorganic & medicinal chemistry letters 20020603
Purine nucleoside phosphorylase from Cellulomonas sp.: physicochemical properties and binding of substrates determined by ligand-dependent enhancement of enzyme intrinsic fluorescence, and by protective effects of ligands on thermal inactivation of the enzyme. Biochimica et biophysica acta 20020603
Evidence for swelling-induced adenosine and adenine nucleotide release in rat cerebral cortex exposed to monocarboxylate-containing or hypotonic artificial cerebrospinal fluids. Neurochemistry international 20020601
Novel missense mutation in the purine nucleoside phosphorylase gene in a Japanese patient with purine nucleoside phosphorylase deficiency. Pediatrics international : official journal of the Japan Pediatric Society 20020601
Clustered DNA damages induced by x rays in human cells. Radiation research 20020601
Proton NMR studies of 5'-d-(TC)(3) (CT)(3) (AG)(3)-3'--a paperclip triplex: the structural relevance of turns. Biophysical journal 20020601
FTIR and UV spectroscopy studies of triplex formation between pyrimidine methoxyethylphosphoramidates alpha-oligodeoxynucleotides and ds DNA targets. Journal of biomolecular structure & dynamics 20020601
Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia. Leukemia 20020601
Gene therapy for prostate cancer delivered by ovine adenovirus and mediated by purine nucleoside phosphorylase and fludarabine in mouse models. Gene therapy 20020601
Purine signaling and potential new therapeutic approach: possible outcomes of NTPDase inhibition. Current drug targets 20020601
Current treatment of follicular non-Hodgkin's lymphoma. European journal of cancer (Oxford, England : 1990) 20020601
Cancer chemotherapy and heterocyclic compounds. Current medicinal chemistry 20020601
Chronic lymphocytic leukemia. Current treatment options in oncology 20020601
A phase I study of AIT-082 in healthy elderly volunteers. Journal of molecular neuroscience : MN 20020601
Variation between sheep in renal excretion of [14C]allantoin. The British journal of nutrition 20020601
Purification and characterization of recombinant Plasmodium falciparum adenylosuccinate synthetase expressed in Escherichia coli. Protein expression and purification 20020601
Diadenosine pentaphosphate vasodilates the forearm vascular bed: inhibition by theophylline and augmentation by dipyridamole. Clinical pharmacology and therapeutics 20020601
Enhanced analysis of purine and pyrimidine bases by the use of double-strand polyaniline coatings in micellar electrokinetic capillary chromatography. Electrophoresis 20020601
Effects of chemical ischemia on purine nucleotides, free radical generation, lipids peroxidation and intracellular calcium levels in C2C12 myotube derived from mouse myocytes. The Journal of veterinary medical science 20020601
Myelodysplasia terminating in acute myeloid leukemia in a hairy cell leukemia patient treated with 2-deoxycoformycin. Leukemia & lymphoma 20020601
Production of hydroxyl free radical in the xanthine oxidase system with addition of 1-methyl-3-nitro-1-nitrosoguanidine. Free radical research 20020601
Comparison of in vivo efficacy of BCX-1777 and cyclosporin in xenogeneic graft-vs.-host disease: the role of dGTP in antiproliferative action of BCX-1777. International immunopharmacology 20020601
Recent aspects of oxidative DNA damage: guanine lesions, measurement and substrate specificity of DNA repair glycosylases. Biological chemistry 20020601
Dietary fiber suppresses elevations of uric acid and allantoin in serum and urine induced by dietary RNA and increases its excretion to feces in rats. Journal of nutritional science and vitaminology 20020601
[Effects of exogenous nucleotides on the proliferation and migration of intestinal epithelial cells]. Wei sheng yan jiu = Journal of hygiene research 20020601
[Study on the silica-induced cytotoxicity and hprt gene mutagenisis in rat lung fibroblasts and alveolar type II epithelial cells]. Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20020601
Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity. Journal of medicinal chemistry 20020523
Molecular identification of a renal urate anion exchanger that regulates blood urate levels. Nature 20020523
On the competition of the purine bases, functionalities of peptide side chains, and protecting agents for the coordination sites of dicationic cisplatin derivatives. Journal of the American Chemical Society 20020522
Specific HIV-1 TAR RNA loop sequence and functional groups are required for human cyclin T1-Tat-TAR ternary complex formation. Biochemistry 20020521
The A167Y mutation converts the herpes simplex virus type 1 thymidine kinase into a guanosine analogue kinase. Biochemistry 20020521
Adenosine acts through an A3 receptor to prevent the induction of murine anti-CD3-activated killer T cells. International journal of cancer 20020520
Recognition of HNA and 1,5-anhydrohexitol nucleotides by DNA metabolizing enzymes. Biochimica et biophysica acta 20020520
First synthesis and anticancer activity of phosmidosine and its related compounds. The Journal of organic chemistry 20020517
'Fleximers'. Design and synthesis of a new class of novel shape-modified nucleosides(1). The Journal of organic chemistry 20020517
Polyploid measles virus with hexameric genome length. The EMBO journal 20020515
New approaches in the development of DNA sensors: hybridization and electrochemical detection of DNA and RNA at two different surfaces. Bioelectrochemistry (Amsterdam, Netherlands) 20020515
Conformational changes during the catalytic cycle of gluconate kinase as revealed by X-ray crystallography. Journal of molecular biology 20020510
Enzyme-substrate interactions in the purine-specific nucleoside hydrolase from Trypanosoma vivax. The Journal of biological chemistry 20020503
Total synthesis of spicamycin. The Journal of organic chemistry 20020503
Purine nucleotide catabolism in rat liver: labelling of uric acid and allantoin after administration of various labelled precursors. Life sciences 20020503
CD80 antigen expression as a predictor of ex vivo chemosensitivity in chronic lymphocytic leukemia. Leukemia research 20020501
Effects of a P-glycoprotein inhibitor on brain and plasma concentrations of anti-human immunodeficiency virus drugs administered in combination in rats. Drug metabolism and disposition: the biological fate of chemicals 20020501
Loss of urate oxidase activity in hominoids and its evolutionary implications. Molecular biology and evolution 20020501
Transcription-targeted gene therapy for androgen-independent prostate cancer. Cancer gene therapy 20020501
Mechanisms of apoptosis induced by purine nucleosides in astrocytes. Glia 20020501
Receptor regulatory properties evident in the molecular similarity of dopamine receptor ligands and purine nucleotides. The Journal of pharmacy and pharmacology 20020501
Theacrine (1,3,7,9-tetramethyluric acid) synthesis in leaves of a Chinese tea, kucha (Camellia assamica var. kucha). Phytochemistry 20020501
The pivotal role of guanine phosphoribosyltransferase in purine salvage by Giardia lamblia. Molecular microbiology 20020501
Arsenate reductase II. Purine nucleoside phosphorylase in the presence of dihydrolipoic acid is a route for reduction of arsenate to arsenite in mammalian systems. Chemical research in toxicology 20020501
Cytotoxic efficacy of bendamustine in human leukemia and breast cancer cell lines. Journal of cancer research and clinical oncology 20020501
The distribution of purine P2X(2) receptors in the guinea-pig enteric nervous system. Histochemistry and cell biology 20020501
Characteristics of Na(+)-dependent intestinal nucleoside transport in the pig. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020501
Gene abnormalities in patients with hemophagocytic lymphohistiocytosis. The Israel Medical Association journal : IMAJ 20020501
Treatment of lethal cowpox virus respiratory infections in mice with 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine and its orally active diacetate ester prodrug. Antiviral research 20020501
High-dose methylprednisolone therapy in multiple sclerosis increases serum uric acid levels. Clinical chemistry and laboratory medicine 20020501
Dyshormonal disorders in gout: experimental and clinical studies. Bulletin of experimental biology and medicine 20020501
Calf spleen purine nucleoside phosphorylase: complex kinetic mechanism, hydrolysis of 7-methylguanosine, and oligomeric state in solution. Biochimica et biophysica acta 20020429
Functional cloning, heterologous expression, and purification of two different N-deoxyribosyltransferases from Lactobacillus helveticus. The Journal of biological chemistry 20020426
Functional studies of potential intrastrand triplex elements in the Escherichia coli genome. Journal of molecular biology 20020426
Preconditioning of rat hearts by adenosine A1 or A3 receptor activation. European journal of pharmacology 20020426
A genome sequence survey of the mollicute corn stunt spiroplasma Spiroplasma kunkelii. FEMS microbiology letters 20020423
Modulation of colony stimulating factor release and apoptosis in human colon cancer cells by anticancer drugs. British journal of cancer 20020422
Determination of purine and pyrimidine bases in DNA by micellar electrokinetic capillary chromatography with electrochemical detection. Journal of chromatography. A 20020419
Sequestering of Eu(III) by a GAAA RNA tetraloop. Journal of the American Chemical Society 20020410
Identification of a novel mycobacterial transcriptional regulator and its involvement in growth rate dependence and stringent control. FEMS microbiology letters 20020409
Covalent analogues of DNA base-pairs and triplets. Part 2: synthesis and cytostatic activity of bis(purin-6-yl)acetylenes,-diacetylenes and related compounds. Bioorganic & medicinal chemistry letters 20020408
Preferential misincorporation of purine nucleotides by human DNA polymerase eta opposite benzo[a]pyrene 7,8-diol 9,10-epoxide deoxyguanosine adducts. The Journal of biological chemistry 20020405
Kinetics of hydrolysis of 8-(arylamino)-2'-deoxyguanosines. The Journal of organic chemistry 20020405
Fast, efficient capillary electrophoresis method for measuring nucleotide degradation and metabolism. Journal of chromatography. A 20020405
Severe energy deprivation of human hibernating myocardium as possible common pathomechanism of contractile dysfunction, structural degeneration and cell death. Journal of the American College of Cardiology 20020403
How does the mitochondrial ADP/ATP carrier distinguish transportable ATP and ADP from untransportable AMP and GTP?Dynamic modeling of the recognition/translocation process in the major substrate binding region. Biochimica et biophysica acta 20020403
A few amino acid substitutions can convert deoxyribonucleoside kinase specificity from pyrimidines to purines. The EMBO journal 20020402
Synthesis and evaluation of organosilicon inhibitors of active purine transport in human osteoblasts. Chembiochem : a European journal of chemical biology 20020402
Ophidian envenomation strategies and the role of purines. Toxicon : official journal of the International Society on Toxinology 20020401
Activation of nonspecific cytotoxic cells (NCC) with synthetic oligodeoxynucleotides and bacterial genomic DNA: binding, specificity and identification of unique immunostimulatory motifs. Developmental and comparative immunology 20020401
Alterations of purine and pyrimidine nucleotide contents in rat corticoencephalic cell cultures following metabolic damage and treatment with openers and blockers of ATP-sensitive potassium channels. Neurochemistry international 20020401
Developmentally regulated expression of a cell surface class I nuclease in Leishmania mexicana. International journal for parasitology 20020401
Role of mizoribine in renal transplantation. Pediatrics international : official journal of the Japan Pediatric Society 20020401
Impairment of mitochondrial DNA repair enzymes against accumulation of 8-oxo-guanine in the spinal motor neurons of amyotrophic lateral sclerosis. Acta neuropathologica 20020401
Effect of inosine on the plasma concentration of uridine and purine bases. Metabolism: clinical and experimental 20020401
Properties of Na(+)-dependent nucleoside transport in the proximal and distal small intestine of cows. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020401
Pharmacokinetics of acyclovir in immunocompromized children with leukopenia and mucositis after chemotherapy: can intravenous acyclovir be substituted by oral valacyclovir? Medical and pediatric oncology 20020401
Distinguishing 'looped-out' and 'stacked-in' DNA bulge conformation using fluorescent 2-aminopurine replacing a purine base. Journal of biomolecular structure & dynamics 20020401
Inosine exerts a broad range of antiinflammatory effects in a murine model of acute lung injury. Annals of surgery 20020401
Lentiviral vectors for efficient transduction of isolated primary quiescent hepatocytes. Journal of hepatology 20020401
Therapeutic potential of a reduced-intensity preparative regimen for allogeneic transplantation with cladribine, busulfan, and antithymocyte globulin against advanced/refractory acute leukemia/lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research 20020401
Cross-linked thymine-purine base tandem lesions: synthesis, characterization, and measurement in gamma-irradiated isolated DNA. Chemical research in toxicology 20020401
Short-term effects of angiotensin II receptor blockade in patients with primary glomerulonephritis: pilot study. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20020401
Interaction of pemetrexed disodium (ALIMTA, multitargeted antifolate) and irradiation in vitro. International journal of radiation oncology, biology, physics 20020401
The involvement of smooth muscle P2X receptors in the prolonged vasorelaxation response to purine nucleotides in the rat mesenteric arterial bed. British journal of pharmacology 20020401
A novel superfamily of transporters for allantoin and other oxo derivatives of nitrogen heterocyclic compounds in Arabidopsis. The Plant cell 20020401
Deletion of dinucleotide repeat (Delta 14 allele) in the methylthioadenosine phosphorylase (MTAP) promoter and the allelotype of MTAP promoter in the Japanese population. Japanese journal of cancer research : Gann 20020401
Mycophenolate mofetil: selective T cell inhibition. The American journal of the medical sciences 20020401
Catabolism of cytoplasmic and intramitochondrial adenine nucleotides in C2C12 skeletal myotube under chemical hypoxia. The Journal of veterinary medical science 20020401
Pemetrexed: a promising new treatment for breast cancer. Seminars in oncology 20020401
5-s-Cysteinyl-conjugates of catecholamines induce cell damage, extensive DNA base modification and increases in caspase-3 activity in neurons. Journal of neurochemistry 20020401
Effect of octreotide acetate on the plasma concentration and urinary excretion of uridine and purine bases. Endocrine journal 20020401
Cold storage of rabbit thoracic aorta in University of Wisconsin solution attenuates P2Y(2) purine receptors. Cryobiology 20020401
A DNA-electrochemical biosensor for screening environmental damage caused by s-triazine derivatives. Analytical and bioanalytical chemistry 20020401
Organometallic ruthenium(II) diamine anticancer complexes: arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts. Journal of the American Chemical Society 20020327
Direct protection of inosine on PC12 cells against zinc-induced injury. Neuroreport 20020325
Benzimidazole-4,7-diones as inhibitors of protozoal (Toxoplasma gondii) purine nucleoside phosphorylase. Bioorganic & medicinal chemistry letters 20020325
Purine and pyrimidine salvage in whole rat brain. Utilization of ATP-derived ribose-1-phosphate and 5-phosphoribosyl-1-pyrophosphate generated in experiments with dialyzed cell-free extracts. The Journal of biological chemistry 20020322
Influence of d orbital occupation on the binding of metal ions to adenine. Journal of the American Chemical Society 20020320
Mass spectrometric assays for the tandem lesion 8,5'-cyclo-2'-deoxyguanosine in mammalian DNA. Biochemistry 20020319
The role of reperfusion injury in photodynamic therapy with 5-aminolaevulinic acid--a study on normal rat colon. British journal of cancer 20020318
Childhood hyperuricemia and acute renal failure resulting from a missense mutation in the HPRT gene. American journal of medical genetics 20020315
alpha-L-ribo-configured locked nucleic acid (alpha-L-LNA): synthesis and properties. Journal of the American Chemical Society 20020313
[The benefits of new immunosuppressive treatments in adult kidney transplantation]. Presse medicale (Paris, France : 1983) 20020309
A molecular basis for the selective recognition of 2-hydroxy-dATP and 8-oxo-dGTP by human MTH1. The Journal of biological chemistry 20020308
Manipulation of plasma uric acid in broiler chicks and its effect on leukocyte oxidative activity. American journal of physiology. Regulatory, integrative and comparative physiology 20020301
A colorimetric assay for the quantitation of free adenine applied to determine the enzymatic activity of ribosome-inactivating proteins. Analytical biochemistry 20020301
Nucleosteroids: carbocyclic nucleoside analogs of androst-4-en-17 beta-ol. Steroids 20020301
New developments in the treatment of inflammatory bowel disease. Expert opinion on investigational drugs 20020301
3,4-Dihydro-6-methyl-3-beta-D-ribofuranosyl-4,5'-cyclo-9H-imidazo[1,2-a]purin-9-one hydrate. Acta crystallographica. Section C, Crystal structure communications 20020301
Uncoupling of protein-3 induces an uncontrolled uncoupling of mitochondria after expression in muscle derived L6 cells. European journal of biochemistry 20020301
Purine biosynthesis. Big in cell division, even bigger in nitrogen assimilation. Plant physiology 20020301
Treatment of children with Langerhans cell histiocytosis with 2-chlorodeoxyadenosine. American journal of hematology 20020301
Leukodystrophy and CSF purine abnormalities associated with isolated 3-methylcrotonyl-CoA carboxylase deficiency. Metabolic brain disease 20020301
Facile synthesis of 9-substituted 9-deazapurines as potential purine nucleoside phosphorylase inhibitors. Chemical & pharmaceutical bulletin 20020301
Hypomethylation and multiple sclerosis, the susceptibility factor? Neurologia (Barcelona, Spain) 20020301
Sodium dependence of nitrofurantoin active transport across mammary epithelia and effects of dipyridamole, nucleosides, and nucleobases. Pharmaceutical research 20020301
P2 receptor modulation and cytotoxic function in cultured CNS neurons. Neuropharmacology 20020301
[Chimeric yeast prions with unstable inheritance]. Genetika 20020301
The role of nucleoside analogues in the treatment of chronic lymphocytic leukemia-lessons learned from prospective randomized trials. Leukemia & lymphoma 20020301
Purine composition of the crystalline cytoplasmic inclusions of Paramecium tetraurelia. Protist 20020301
Molecular mechanism of DApd/DXG against zidovudine- and lamivudine- drug resistant mutants: a molecular modelling approach. Antiviral chemistry & chemotherapy 20020301
Characterization of the Hansenula polymorpha PUR7 gene and its use as selectable marker for targeted chromosomal integration. FEMS yeast research 20020301
Adenosine as a neuroprotectant: therapeutic perspectives. Expert review of neurotherapeutics 20020301
Correlation between chromosome damage and apoptosis induced by fludarabine and idarubicin in normal human lymphocytes. Toxicology 20020227
Oxidative stress and dopamine deficiency in a genetic mouse model of Lesch-Nyhan disease. Brain research. Developmental brain research 20020227
Specificity analysis of the conserved hexanucleotides for the replication of bamboo mosaic potexvirus RNA. Virus research 20020226
Screening method for inherited disorders of purine and pyrimidine metabolism by capillary electrophoresis with reversed electroosmotic flow. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020215
8-Chloro-dGTP, a hypochlorous acid-modified nucleotide, is hydrolyzed by hMTH1, the human MutT homolog. FEBS letters 20020213
Extracellular nucleotides inhibit growth of human oesophageal cancer cells via P2Y(2)-receptors. British journal of cancer 20020212
Protonation studies of modified adenine and adenine nucleotides by theoretical calculations and (15)N NMR. The Journal of organic chemistry 20020208
Anoxia-induced changes in purine nucleoside metabolism of in vitro aged human fibroblasts. Life sciences 20020208
The sodium ions inside a lipophilic G-quadruplex channel as probed by solid-state (23)Na NMR. Journal of the American Chemical Society 20020206
L-Carnitine L-tartrate supplementation favorably affects markers of recovery from exercise stress. American journal of physiology. Endocrinology and metabolism 20020201
Role of glutathione in the multidrug resistance protein 4 (MRP4/ABCC4)-mediated efflux of cAMP and resistance to purine analogues. The Biochemical journal 20020201
Overexpression of Escherichia coli genes encoding nucleoside phosphorylases in the pET/Bl21(DE3) system yields active recombinant enzymes. Protein expression and purification 20020201
Endothelial cell compatibility of azithromycin and erythromycin. The Journal of antimicrobial chemotherapy 20020201
Metabolic treatment of hyperuricosuric autism. Progress in neuro-psychopharmacology & biological psychiatry 20020201
Platinum complexes of oxopurines: cis-bis(theophyllinato-N7)bis(triphenylphosphine)platinum(II) and cis-chloro(theobrominato-N1)bis(triphenylphosphine)platinum(II) ethanol hemisolvate. Acta crystallographica. Section C, Crystal structure communications 20020201
Structural evidence for ammonia tunneling across the (beta alpha)(8) barrel of the imidazole glycerol phosphate synthase bienzyme complex. Structure (London, England : 1993) 20020201
Conceptual aspects of combining rituximab and Campath-1H in the treatment of chronic lymphocytic leukemia. Seminars in oncology 20020201
Formation and thermodynamic stability of intermolecular (R*R*Y) DNA triplex in GAA/TTC repeats associated with Freidreich's ataxia. Journal of biomolecular structure & dynamics 20020201
Using a Euclid distance discriminant method to find protein coding genes in the yeast genome. Computers & chemistry 20020201
Capillary electrophoresis for detection of inherited disorders of purine and pyrimidine metabolism: a selective approach. Electrophoresis 20020201
Primordial coding of amino acids by adsorbed purine bases. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20020201
Regulation of alternative splicing of alpha-actinin transcript by Bruno-like proteins. Genes to cells : devoted to molecular & cellular mechanisms 20020201
Effect of strand orientation on the interaction of berenil with DNA triple helices. European biophysics journal : EBJ 20020201
Serum xanthine oxidase: origin, regulation, and contribution to control of trypanosome parasitemia. Antioxidants & redox signaling 20020201
Large-cell transformation of chronic lymphocytic leukemia and follicular lymphoma during or soon after treatment with fludarabine-rituximab-containing regimens: natural history- or therapy-related complication? European journal of haematology 20020201
Chronic lymphocytic leukaemia--the haematologic basis for diagnosis and treatment. Hematology (Amsterdam, Netherlands) 20020201
The efflux of purine nucleobases and nucleosides from the rat brain. Neuroscience letters 20020125
Synthesis of 2'-O-[2-[(N,N-dimethylamino)oxy]ethyl] modified nucleosides and oligonucleotides. The Journal of organic chemistry 20020125
Adenine-aptamer complexes: a bipartite RNA site that binds the adenine nucleic base. The Journal of biological chemistry 20020118
Open and closed conformation of the E. coli purine nucleoside phosphorylase active center and implications for the catalytic mechanism. Journal of molecular biology 20020118
Resistance of leukemic cells to 2-chlorodeoxyadenosine is due to a lack of calcium-dependent cytochrome c release. Blood 20020115
Pathways for alpha-D-ribose utilization for nucleobase salvage and 5-fluorouracil activation in rat brain. Biochemical pharmacology 20020115
Chemical modification of the third strand: differential effects on purine and pyrimidine triple helix formation. Biochemistry 20020108
Analysis of purines and pyrimidines by mixed partition-adsorption normal-phase high-performance liquid chromatography. Journal of chromatography. A 20020104
Rebek imides and their adenine complexes: preferences for Hoogsteen binding in the solid state and in solution. Chemistry (Weinheim an der Bergstrasse, Germany) 20020104
Superoxide activates mitochondrial uncoupling proteins. Nature 20020103
Anti-angiogenic activity of a novel multi-substrate analogue inhibitor of thymidine phosphorylase. FEBS letters 20020102
Synthesis of novel (2R,4R)- and (2S,4S)-iso dideoxynucleosides with exocyclic methylene as potential antiviral agents. Bioorganic & medicinal chemistry 20020101
Adenosine-mediated cardioprotection in ischemic-reperfused mouse heart. Journal of cardiovascular pharmacology 20020101
Structural analyses reveal two distinct families of nucleoside phosphorylases. The Biochemical journal 20020101
Synergistic cell-killing effect of a combination of hyperthermia and heavy ion beam irradiation: in expectation of a breakthrough in the treatment of refractory cancers (review). International journal of molecular medicine 20020101
HPLC determination of thiopurine nucleosides and nucleotides in vivo in lymphoblasts following mercaptopurine therapy. Clinical chemistry 20020101
Molecular cloning of Trypanosoma brucei CK2 catalytic subunits: the alpha isoform is nucleolar and phosphorylates the nucleolar protein Nopp44/46. Molecular and biochemical parasitology 20020101
Partial hypoxanthine-Guanine phosphoribosyltransferase deficiency as the unsuspected cause of renal disease spanning three generations: a cautionary tale. Pediatrics 20020101
Inflammatory bowel disease. Endoscopy 20020101
The metabolism of 2-methyladenosine in Mycobacterium smegmatis. Microbiology (Reading, England) 20020101
Dioxolane guanosine, the active form of the prodrug diaminopurine dioxolane, is a potent inhibitor of drug-resistant HIV-1 isolates from patients for whom standard nucleoside therapy fails. Journal of acquired immune deficiency syndromes (1999) 20020101
Linkage between toxin production and purine biosynthesis in Clostridium difficile. Journal of medical microbiology 20020101
Characterization of the substrate specificity of a human 5-hydroxymethyluracil glycosylase activity. Chemical research in toxicology 20020101
[The pyrimidine-biosynthetic (pyr) gene cluster in trypanosomes]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20020101
Nucleotide-mediated relaxation in guinea-pig aorta: selective inhibition by MRS2179. British journal of pharmacology 20020101
Progress towards the discovery of xanthine oxidase inhibitors. Current medicinal chemistry 20020101
Raltitrexed (Tomudex) administration in patients with relapsed metastatic colorectal cancer after weekly irinotecan/5-Fluorouracil/Leucovorin chemotherapy. BMC cancer 20020101
[Pyrimidine oligodeoxyxylonucleotides form triplexes with purine DNA in neutral media]. Molekuliarnaia biologiia 20020101
Potential therapeutic targets in the rapidly expanding field of purinergic signalling. Clinical medicine (London, England) 20020101
Effects of high inspired oxygen fraction during elective caesarean section under spinal anaesthesia on maternal and fetal oxygenation and lipid peroxidation. British journal of anaesthesia 20020101
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[Gout: current views. Stage oriented treatment]. Klinicheskaia meditsina 20020101
Persistent developmental delay despite successful bone marrow transplantation for purine nucleoside phosphorylase deficiency. Journal of pediatric hematology/oncology 20020101
RNA:(guanine-N2) methyltransferases RsmC/RsmD and their homologs revisited--bioinformatic analysis and prediction of the active site based on the uncharacterized Mj0882 protein structure. BMC bioinformatics 20020101
Methylenetetrahydrofolate reductase: a common human polymorphism and its biochemical implications. Chemical record (New York, N.Y.) 20020101
Human sperm immobilizing activity of aminophenyl arsenic acid and its N-substituted quinazoline, pyrimidine, and purine derivatives: protective effect of glutathione. Reproductive toxicology (Elmsford, N.Y.) 20020101
Methylthioadenosine phosphorylase as target for chemoselective treatment of T-cell acute lymphoblastic leukemic cells. Blood cells, molecules & diseases 20020101
Synthesis, antiviral and cytostatic activities, of carbocyclic nucleosides incorporating a modified cyclopentane ring. IV. Adenosine and uridine analogues. Nucleosides, nucleotides & nucleic acids 20020101
Xanthine oxidase contributes to preconditioning's preservation of left ventricular developed pressure in isolated rat heart: developed pressure may not be an appropriate end-point for studies of preconditioning. Basic research in cardiology 20020101
Anti-adenosine deaminase antibodies in lupus erythematosus. Lupus 20020101
6-thioguanine in the treatment of psoriasis: a case report and literature review. Journal of cutaneous medicine and surgery 20020101
Xanthine oxidase activation in mild gestational hypertension. Hypertension in pregnancy 20020101
Evolution of gene fusions: horizontal transfer versus independent events. Genome biology 20020101
Targeting fragile X. Genome biology 20020101
Potential role of purinergic signalling in cochlear pathology. Audiology & neuro-otology 20020101
[Riboflavin overproduction in 4-aminopyrazole[3,4-d]pyrimidine-treated yeast Pichia guilliermondii]. Prikladnaia biokhimiia i mikrobiologiia 20020101
European best practice guidelines for renal transplantation. Section IV: Long-term management of the transplant recipient. IV.9.1. Haematological complications. Anaemia. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020101
Gene discovery within the planctomycete division of the domain Bacteria using sequence tags from genomic DNA libraries. Genome biology 20020101
Waldenström's macroglobulinaemia: current therapy and future approaches. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20020101
Molecular action of methotrexate in inflammatory diseases. Arthritis research 20020101
Epidemiology of hairy cell leukemia in Iceland. The hematology journal : the official journal of the European Haematology Association 20020101
Oral self-mutilation in the Lesch-Nyhan syndrome. ASDC journal of dentistry for children 20020101
Novel cyanine dye-labeled dideoxynucleoside triphosphates for DNA sequencing. Bioconjugate chemistry 20020101
Energy metabolism during microsurgical transfer of human skeletal muscle assessed by high-pressure liquid chromatography and by 31P-nuclear magnetic resonance. Scandinavian journal of plastic and reconstructive surgery and hand surgery 20020101
[Clinico-hematological effectiveness in losartan for treating hypertensive patients]. Likars'ka sprava 20020101
Quantitative assessment of the use of modified nucleoside triphosphates in expression profiling: differential effects on signal intensities and impacts on expression ratios. BMC biotechnology 20020101
Pervasive properties of the genomic signature. BMC genomics 20020101
Monocarboxylate transporters and lactate metabolism in equine athletes: a review. Acta veterinaria Scandinavica 20020101
Current and developing chemotherapy for CLL. Medical oncology (Northwood, London, England) 20020101
[The increasing mutagenic effect of nitrosoguanidine under the influence of modified bases during inhibition of repair AGT enzyme in mammalian somatic cells in vitro]. TSitologiia i genetika 20020101
Hematopoietic stem-cell transplantation for Hodgkin's disease (HD): current status. Cytotherapy 20020101
Epstein-Barr virus encoded nuclear protein EBNA-3 binds a novel human uridine kinase/uracil phosphoribosyltransferase. BMC cell biology 20020101
Purine, kynurenine, neopterin and lipid peroxidation levels in inflammatory bowel disease. Journal of biomedical science 20020101
Artificial ribonucleases: efficient and specific in vitro cleavage of human c-raf-1 RNA. Bioconjugate chemistry 20020101
The effects of Neotrofin on septodentate sprouting after unilateral entorhinal cortex lesions in rats. Restorative neurology and neuroscience 20020101
Adenosine 5'-triphosphate axis in obstructive airway diseases. American journal of therapeutics 20020101
Waldenström's macroglobulinemia. Clinical journal of oncology nursing 20020101
Specificity of DNA triple helix formation analyzed by a FRET assay. BMC biochemistry 20020101
Purine nucleosides bearing 1-alkynyl chains as adenosine receptor agonists. Current pharmaceutical design 20020101
Applications of adenosine receptor ligands in medical imaging by positron emission tomography. Current pharmaceutical design 20020101
Control of pyrimidine synthesis in Pseudomonas fragi. Letters in applied microbiology 20020101
[Features of the kinetics of accumulating entomocidal exotoxins of Bacillus thuringiensis subsp. thuringiensis during fermentation stage of bitoxibacillin production]. Prikladnaia biokhimiia i mikrobiologiia 20020101
Evidence for non-independent gating of P2X2 receptors expressed in Xenopus oocytes. BMC neuroscience 20020101
Exploring the conditional coregulation of yeast gene expression through fuzzy k-means clustering. Genome biology 20020101
Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands. Genome biology 20020101
The society of genes: networks of functional links between genes from comparative genomics. Genome biology 20020101
Finding signals that regulate alternative splicing in the post-genomic era. Genome biology 20020101
Inosine stimulates axon growth in vitro and in the adult CNS. Progress in brain research 20020101
Comparison of the interaction of uridine, cytidine, and other pyrimidine nucleoside analogues with recombinant human equilibrative nucleoside transporter 2 (hENT2) produced in Saccharomyces cerevisiae. Biochemistry and cell biology = Biochimie et biologie cellulaire 20020101
Analysis of relative positions of ribonucleotide bases in a crystal structure of ribosome. Nucleosides, nucleotides & nucleic acids 20020101
Oxidant injury in neonatal erythrocytes during the perinatal period. Acta paediatrica (Oslo, Norway : 1992). Supplement 20020101
[Metabolic syndrome from the point of view of a cardiologist: diagnosis, non drug and drug treatment]. Kardiologiia 20020101
[Pathogenetic role of moxonidine in the treatment of hypertension in postmenopausal women]. Kardiologiia 20020101
Modulatory effect of adenosine receptors on the ascending and descending neural reflex responses of rat ileum. BMC neuroscience 20020101
Mutations in the Lactococcus lactis Ll.LtrB group II intron that retain mobility in vivo. BMC molecular biology 20020101
Kelley-Seegmiller syndrome in a patient with complete hypoxanthine-guanine phosphoribosyltransferase deficiency. Clinical and experimental rheumatology 20020101
Allopurinol for chronic prostatitis. The Cochrane database of systematic reviews 20020101
[Evaluation of hypoxic state in experimental animals induced by Yersinia pestis antigens]. Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20020101
[Coding in molecular biology and radiation]. Radiatsionnaia biologiia, radioecologiia 20020101
Life before RNA. Astrobiology 20020101
The mitochondrial uncoupling proteins. Genome biology 20020101
Plasma 5'-nucleotidase activities and uric acid levels in women with pre-eclampsia. Gynecologic and obstetric investigation 20020101
[The hematology clinic]. Revue medicale de Bruxelles 20020101
[The study and comparative evaluation of the actoprotective activity of ATF-LONG in experiment]. Likars'ka sprava 20020101
Purine degradation in the edible mushroom Agaricus bisporus. Folia microbiologica 20020101
Elevation of antioxidant potency in mice brain by low-dose X-ray irradiation and its effect on Fe-NTA-induced brain damage. Physiological chemistry and physics and medical NMR 20020101
Substrate recognition by the human MTH1 protein. Nucleic acids research. Supplement (2001) 20020101
Synthesis and properties of N-t-butylaminoxyl nucleosides. Nucleic acids research. Supplement (2001) 20020101
Purine and pyrimidine nucleotide synthesis and metabolism. The arabidopsis book 20020101
Synthesis and biological evaluation of myoseverin derivatives: microtubule assembly inhibitors. Journal of medicinal chemistry 20011220
Structural basis for the binding affinity of xanthines with the DNA intercalator acridine orange. Journal of medicinal chemistry 20011220
6-bromopurine nucleosides as reagents for nucleoside analogue synthesis. The Journal of organic chemistry 20011214
A nonspecific nucleoside hydrolase from Leishmania donovani: implications for purine salvage by the parasite. Gene 20011212
A rationally designed oligopeptide shows significant conformational changes upon binding to sulphate ions. Biosensors & bioelectronics 20011201
Evolving medical therapies for Crohn's disease. Current gastroenterology reports 20011201
Crystal structures of coaxially stacked kissing complexes of the HIV-1 RNA dimerization initiation site. Nature structural biology 20011201
Small-molecule metabolism: an enzyme mosaic. Trends in biotechnology 20011201
Anti-inflammatory effects of inosine in human monocytes, neutrophils and epithelial cells in vitro. International journal of molecular medicine 20011201
A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines. International journal of oncology 20011201
Scanning mutagenesis identifies critical residues in the rinderpest virus genome promoter. The Journal of general virology 20011201
Multinuclear magnetic resonance spectroscopy studies of brain purines in major depression. The American journal of psychiatry 20011201
Blood transfusion causes deterioration in liver regeneration after partial hepatectomy in rats. The Journal of surgical research 20011201
Rituximab, a chimaeric anti-CD20 monoclonal antibody, in the treatment of hairy cell leukaemia. British journal of haematology 20011201
The role of purine analogue combinations in the management of acute leukemias. Hematological oncology 20011201
3,7-Dimethylguanine, a new purine from a Philippine sponge Zyzzya fuliginosa. Chemical & pharmaceutical bulletin 20011201
Enzymatic properties of sialic acid binding lectin from Rana catesbeiana modified with a water-soluble carbodiimide in the presence of various nucleophiles. Biological & pharmaceutical bulletin 20011201
Systemic administration of LPD prepared with CpG oligonucleotides inhibits the growth of established pulmonary metastases by stimulating innate and acquired antitumor immune responses. Cancer immunology, immunotherapy : CII 20011201
Elevation of extracellular glutamate in the final, ischemic stage of progressive epidural mass lesion in cats. Journal of neurotrauma 20011201
A handy detection cell for end-column electrochemical detection in capillary electrophoresis. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20011201
Human aldehyde dehydrogenase catalytic activity and structural interactions with coenzyme analogs. Journal of biomolecular structure & dynamics 20011201
The purine degradation pathway: possible role in paralytic shellfish toxin metabolism in the cyanobacterium Planktothrix sp. FP1. Environment international 20011201
MRP subfamily transporters and resistance to anticancer agents. Journal of bioenergetics and biomembranes 20011201
The oxpA5 mutation of Aspergillus nidulans is an allele of adB, the gene encoding adenylosuccinate synthetase. Molecular genetics and genomics : MGG 20011201
Novel cross-strand three-purine stack of the highly conserved 5'-GA/AAG-5' internal loop at the 3'-end termini of Parvovirus genomes. Journal of biomolecular NMR 20011201
[Hairy cell leukemia: report of 8 cases]. La Tunisie medicale 20011201
[Evaluation of glucose, insulin, C-peptide uric acid serum levels in patients with psoriasis]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20011201
Sinusoidal endothelial cell injury by superoxide anion and iron in the Propionibacterium acnes-pretreated and lipopolysaccharide-stimulated rat liver. Liver 20011201
Specific treatment of Chagas disease: current status and new developments. Current opinion in infectious diseases 20011201
[Renal replacement therapy results in correction of plasma and erythrocyte adenine nucleotide abnormalities in patients with chronic renal failure]. Polskie Archiwum Medycyny Wewnetrznej 20011201
Absorption coefficient and purine photobleaching rate in colon mucosa during resonance Raman spectroscopy at 251 nm. Applied optics 20011201
Syntheses of puromycin from adenosine and 7-deazapuromycin from tubercidin, and biological comparisons of the 7-aza/deaza pair. The Journal of organic chemistry 20011130
A unique ring-expanded acyclic nucleoside analogue that inhibits both adenosine deaminase (ADA) and guanine deaminase (GDA; guanase): synthesis and enzyme inhibition studies of 4,6-diamino-8H-1-hydroxyethoxymethyl-8-iminoimidazo[4,5-e][1,3]diazepine. Bioorganic & medicinal chemistry letters 20011119
Quadruple intercalated G-6 stack: a possible motif in the fold-back structure of the Drosophila centromeric dodeca-satellite? Journal of molecular biology 20011116
Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation. Analytical biochemistry 20011115
Hypoxanthine-guanine phosphoribosyltransferase-deficiency produces aberrant neurite outgrowth of rodent neuroblastoma used to model the neurological disorder Lesch Nyhan syndrome. Neuroscience letters 20011113
Abnormal development of hypoxanthine-guanine phosphoribosyltransferase-deficient CNS neuroblastoma. Brain research 20011109
In vitro bioassays for anticancer drug screening: effects of cell concentration and other assay parameters on growth inhibitory activity. Cancer letters 20011108
Enantiomeric synthesis of D- and L-cyclopentenyl nucleosides and their antiviral activity against HIV and West Nile virus. Journal of medicinal chemistry 20011108
Synthesis of 9-(2,3-dideoxy-2-fluoro-beta-D-threo-pentofuranosyl)adenine (FddA) via a purine 3'-deoxynucleoside. The Journal of organic chemistry 20011102
Localization of the Plasmodium falciparum PfNT1 nucleoside transporter to the parasite plasma membrane. The Journal of biological chemistry 20011102
Substitution F569S converts UapA, a specific uric acid-xanthine transporter, into a broad specificity transporter for purine-related solutes. Journal of molecular biology 20011102
Indication, surgical technique and outcome of orthotopic renal transplantation. The Journal of urology 20011101
Differential kinetics of transport of 2',3'-dideoxyinosine and adenosine via concentrative Na+ nucleoside transporter CNT2 cloned from rat blood-brain barrier. The Journal of pharmacology and experimental therapeutics 20011101
Purine nucleoside-dependent inhibition of cellular proliferation in 1321N1 human astrocytoma cells. The Journal of pharmacology and experimental therapeutics 20011101
Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells. Molecular pharmacology 20011101
Variability of the CD36 gene in West Africa. Human mutation 20011101
Azathioprine treatment and male fertility in inflammatory bowel disease. Gastroenterology 20011101
Somatic hypermutation targeting to intrinsic hotspots of immunoglobulin genes in follicular lymphoma and multiple myeloma. Leukemia 20011101
Structure-activity relationships of diadenosine polyphosphates (Ap(n)As), adenosine polyphospho guanosines (Ap(n)Gs) and guanosine polyphospho guanosines (Gp(n)Gs) at P2 receptors in the rat mesenteric arterial bed. British journal of pharmacology 20011101
Review article: the treatment of inflammatory bowel disease with 6-mercaptopurine or azathioprine. Alimentary pharmacology & therapeutics 20011101
Cell cycle-dependent control of polarised development by a cyclin-dependent kinase-like protein in the Fucus zygote. Development (Cambridge, England) 20011101
5'-Adenosine monophosphate and adenosine metabolism, and adenosine responses in mouse, rat and guinea pig heart. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011101
Elimination voltammetry of adenine and cytosine mixtures. Bioelectrochemistry (Amsterdam, Netherlands) 20011101
Functional properties and responses to ischaemia-reperfusion in Langendorff perfused mouse heart. Experimental physiology 20011101
Novel 6-substituted uracil analogs as inhibitors of the angiogenic actions of thymidine phosphorylase. Biochemical pharmacology 20011101
Synthetic 1,4-anthracenediones, which block nucleoside transport and induce DNA fragmentation, retain their cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines. Anti-cancer drugs 20011101
Secondary DNA structures as molecular targets for cancer therapeutics. Biochemical Society transactions 20011101
A history of UCP1. Biochemical Society transactions 20011101
Fragmentation of photomodified oligodeoxynucleotides adducted with metal ions in an electrospray-ionization ion-trap mass spectrometer. Journal of the American Society for Mass Spectrometry 20011101
[Mitochondrial uncoupling protein as a target of pharmacotherapy for obesity]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20011101
Novel deoxynucleoside-phosphorylating enzymes in mycoplasmas: evidence for efficient utilization of deoxynucleosides. Molecular microbiology 20011101
Caffeine and the G2/M block override: a concept resulting from a misleading cell kinetic delay, independent of functional p53. International journal of cancer 20011101
Comment on 'new infrared spectra and tautomeric studies of purine and alpha L-alanine with an innovative sampling technique.'. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20011101
Progress in CLL, chemotherapy, antibodies and transplantation. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20011101
Neurocognitive functioning in Lesch-Nyhan disease and partial hypoxanthine-guanine phosphoribosyltransferase deficiency. Journal of the International Neuropsychological Society : JINS 20011101
Influence of ambient temperature on plasma ammonia and lactate accumulation during prolonged submaximal and self-paced running. European journal of applied physiology 20011101
Synthesis and biological properties of C-2, C-8, N-9 substituted 6-(3-chloroanilino)purine derivatives as cyclin-dependent kinase inhibitors. Part II. Archiv der Pharmazie 20011101
Advances in the chemistry and pharmacology of ecteinascidins, a promising new class of anti-cancer agents. Current medicinal chemistry. Anti-cancer agents 20011101
Regioselective 2'-silylation of purine ribonucleosides for phosphoramidite RNA synthesis. Current protocols in nucleic acid chemistry 20011101
Extracellular nucleotides induce arterial smooth muscle cell migration via osteopontin. Circulation research 20011026
Three-dimensional structure of a hyperthermophilic 5'-deoxy-5'-methylthioadenosine phosphorylase from Sulfolobus solfataricus. The Journal of biological chemistry 20011019
'Fleximers'. Design and synthesis of two novel split nucleosides. Organic letters 20011004
Catabolism of exogenous deoxyinosine in cultured epithelial amniotic cells. Biochimica et biophysica acta 20011003
Glutathione S-transferase polymorphisms influence the level of oxidative DNA damage and antioxidant protection in humans. Mutation research 20011001
Development of a bacterial screen for novel hypoxanthine-guanine phosphoribosyltransferase substrates. Journal of molecular microbiology and biotechnology 20011001
Participation of ATP in cell volume regulation in the endothelium after hypotonic stress. Clinical and experimental pharmacology & physiology 20011001
Cardioprotection with adenosine metabolism inhibitors in ischemic-reperfused mouse heart. Cardiovascular research 20011001
The A3 adenosine receptor as a new target for cancer therapy and chemoprotection. Experimental cell research 20011001
High-level expression and one-step purification of cyclic amidohydrolase family enzymes. Protein expression and purification 20011001
Preliminary analysis and annotation of the partial genome sequence of Francisella tularensis strain Schu 4. Journal of applied microbiology 20011001
Transactivation via RAR/RXR-Sp1 interaction: characterization of binding between Sp1 and GC box motif. Molecular endocrinology (Baltimore, Md.) 20011001
In vitro effect of alkaloids on bloodstream forms of Trypanosoma brucei and T. congolense. Planta medica 20011001
A calorimetric study of 3d metal ions-acyclovir interactions. The 2-hydroxyethoxymethyl group of acyclovir mimics the role of ribose in deoxy-guanosine and guanosine promoting the coordination through N(7). Journal of inorganic biochemistry 20011001
Effect of norepinephrine on the urinary excretion of purine bases and oxypurinol. Metabolism: clinical and experimental 20011001
Structure of E. coli 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase reveals similarity to the purine nucleoside phosphorylases. Structure (London, England : 1993) 20011001
Crystal structure of imidazole glycerol phosphate synthase: a tunnel through a (beta/alpha)8 barrel joins two active sites. Structure (London, England : 1993) 20011001
Developmental variation of sugars, carboxylic acids, purine alkaloids, fatty acids, and endoproteinase activity during maturation of Theobroma cacao L. seeds. Journal of agricultural and food chemistry 20011001
Effect of fenofibrate on plasma concentration and urinary excretion of purine bases and oxypurinol. The Journal of rheumatology 20011001
Inosine reduces systemic inflammation and improves survival in septic shock induced by cecal ligation and puncture. American journal of respiratory and critical care medicine 20011001
Folate deficiency-induced oxidative stress and apoptosis are mediated via homocysteine-dependent overproduction of hydrogen peroxide and enhanced activation of NF-kappaB in human Hep G2 cells. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20011001
Cardiac myocyte adenosine receptors and caveolae. Trends in cardiovascular medicine 20011001
Fragile X syndrome and Friedreich's ataxia: two different paradigms for repeat induced transcript insufficiency. Brain research bulletin 20011001
Primary prophylaxis with lamivudine of hepatitis B virus reactivation in chronic HbsAg carriers with lymphoid malignancies treated with chemotherapy. British journal of haematology 20011001
Favourable response to therapy with the anti-CD20 monoclonal antibody rituximab in primary chronic cold agglutinin disease. British journal of haematology 20011001
Chromosome and oxidative damage biomarkers in lymphocytes of Parkinson's disease patients. International journal of hygiene and environmental health 20011001
Measurement of small scalar and dipolar couplings in purine and pyrimidine bases. Journal of biomolecular NMR 20011001
Ordered biochemical program of gene expression in cancer cells. Biochemistry. Biokhimiia 20011001
Successful treatment with low-dose splenic irradiation for massive splenomegaly in an elderly patient with hairy-cell leukemia. European journal of haematology 20011001
Synthesis and analysis of RNA containing 6-trifluoromethylpurine ribonucleoside. Organic letters 20010920
Expression of hMTH1 in the hippocampi of control and Alzheimer's disease. Neuroreport 20010917
Effect of single mutations on the specificity of Escherichia coli FPG protein for excision of purine lesions from DNA damaged by free radicals. Free radical biology & medicine 20010915
Transport of cyclic nucleotides and estradiol 17-beta-D-glucuronide by multidrug resistance protein 4. Resistance to 6-mercaptopurine and 6-thioguanine. The Journal of biological chemistry 20010907
Aromatic dienophiles. 1. A theoretical study of an inverse-electron demand Diels-Alder reaction between 2-aminopyrrole and 1,3,5-triazine. The Journal of organic chemistry 20010907
Synthesis and purine receptor affinity of 6-oxopurine nucleosides and nucleotides containing (N)-methanocarba-pseudoribose rings. Bioorganic & medicinal chemistry letters 20010903
The fragile X mental retardation protein binds specifically to its mRNA via a purine quartet motif. The EMBO journal 20010903
Stabilities and isomeric equilibria in solutions of monomeric metal-ion complexes of guanosine 5'-triphosphate (GTP4-) and inosine 5'-triphosphate (ITP4-) in comparison with those of adenosine 5'-triphosphate (ATP4-). Chemistry (Weinheim an der Bergstrasse, Germany) 20010903
The role of serine hydroxymethyltransferase isozymes in one-carbon metabolism in MCF-7 cells as determined by (13)C NMR. Archives of biochemistry and biophysics 20010901
The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells. British journal of pharmacology 20010901
Structure of a pseudo-16-mer DNA with stacked guanines and two G-A mispairs complexed with the N-terminal fragment of Moloney murine leukemia virus reverse transcriptase. Acta crystallographica. Section D, Biological crystallography 20010901
Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro. Hepatology (Baltimore, Md.) 20010901
Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice. Carcinogenesis 20010901
Macrophages require different nucleoside transport systems for proliferation and activation. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010901
A novel parasite-derived suicide gene for cancer gene therapy with specificity for lung cancer cells. Human gene therapy 20010901
Caffeine: a well known but little mentioned compound in plant science. Trends in plant science 20010901
Profiles of purine and pyrimidine nucleotides in fresh and manufactured tea leaves. Journal of agricultural and food chemistry 20010901
Mycophenolate mofetil treatment accelerates recovery from experimental allergic encephalomyelitis. International immunopharmacology 20010901
Chronic T-cell lymphoproliferative disease expressing natural killer cell receptors: clinicopathological and molecular features. Cancer genetics and cytogenetics 20010901
Concentrations of nucleotides, nucleosides, purine bases, oxypurines, uric acid, and neuron-specific enolase in the cerebrospinal fluid of children with sepsis. Journal of child neurology 20010901
[Recent progress in the treatment of malignant lymphoma]. Gan to kagaku ryoho. Cancer & chemotherapy 20010901
Effect of transketolase modifications on carbon flow to the purine-nucleotide pathway in Corynebacterium ammoniagenes. Applied microbiology and biotechnology 20010901
Fulminant hepatitis B virus reactivation with concomitant listeriosis after fludarabine and rituximab therapy: case report. Annals of hematology 20010901
[Establishment of human neuroectodermal tumor cell line (PFSK) with stable expression of xanthine oxidoreductase]. Shi yan sheng wu xue bao 20010901
Ribavirin: recent insights into antiviral mechanisms of action. Current opinion in drug discovery & development 20010901
V-shaped scaffold: a new architectural motif identified in an A x (G x G x G x G) pentad-containing dimeric DNA quadruplex involving stacked G(anti) x G(anti) x G(anti) x G(syn) tetrads. Journal of molecular biology 20010831
Effects of hypothermic machine perfusion on rat liver function depending on the route of perfusion. Transplantation 20010827
Simultaneous determination of six adenyl purines in human plasma by high-performance liquid chromatography with fluorescence derivatization. Journal of chromatography. B, Biomedical sciences and applications 20010825
Synthesis of bicyclic pyrimidine derivatives as ATP analogues. The Journal of organic chemistry 20010824
Synthesis of 6-(2-thienyl)purine nucleoside derivatives that form unnatural base pairs with pyridin-2-one nucleosides. Bioorganic & medicinal chemistry letters 20010820
Structure and dimerization of HIV-1 kissing loop aptamers. Journal of molecular biology 20010817
Discovery of estrogen sulfotransferase inhibitors from a purine library screen. Journal of medicinal chemistry 20010816
Regulation of mesangial cell function by vasodilatory signaling molecules. Cardiovascular research 20010815
SCID in Jack Russell terriers: a new animal model of DNA-PKcs deficiency. Journal of immunology (Baltimore, Md. : 1950) 20010815
Detailed analysis of RNA-protein interactions within the ribosomal protein S8-rRNA complex from the archaeon Methanococcus jannaschii. Journal of molecular biology 20010810
Acivicin induces apoptosis independently of gamma-glutamyltranspeptidase activity. Biochemical and biophysical research communications 20010803
Inactivation of O(6)-methylguanine-DNA methyltransferase by glucose-conjugated inhibitors. International journal of cancer 20010801
DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by (32)P-postlabeling. International journal of cancer 20010801
Structure-activity relationships and inhibitory effects of various purine derivatives on the in vitro growth of Plasmodium falciparum. Biochemical pharmacology 20010801
Adenosine-mediated mast cell degranulation in adenosine deaminase-deficient mice. The Journal of pharmacology and experimental therapeutics 20010801
Determination of aliphatic side-chain conformation using cross-correlated relaxation: application to an extraordinarily stable 2'-aminoethoxy-modified oligonucleotide triplex. Journal of the American Chemical Society 20010801
Differing contribution of thiopurine methyltransferase to mercaptopurine versus thioguanine effects in human leukemic cells. Cancer research 20010801
Determination of the effects of mycophenolic acid on the nucleotide pool of human peripheral blood mononuclear cells in vitro by high-performance liquid chromatography. Clinica chimica acta; international journal of clinical chemistry 20010801
In vitro effects of mycophenolic acid on the nucleotide pool and on the expression of adhesion molecules of human umbilical vein endothelial cells. Clinica chimica acta; international journal of clinical chemistry 20010801
Relationship between dopamine-stimulated phospholipid methylation and the single-carbon folate pathway. Journal of neurochemistry 20010801
Reversal of cytosine arabinoside (ara-C) resistance by the synergistic combination of 6-thioguanine plus ara-C plus PEG-asparaginase (TGAP) in human leukemia lines lacking or expressing p53 protein. Cancer chemotherapy and pharmacology 20010801
Structural basis for allosteric substrate specificity regulation in anaerobic ribonucleotide reductases. Structure (London, England : 1993) 20010801
[Evaluation of the tonic and phasic effects of endogenous adenosine on the transmitter secretion in the neuromuscular junction]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20010801
Infectious complications of purine analog therapy. Current opinion in infectious diseases 20010801
Multiple cleavage activities of endonuclease V from Thermotoga maritima: recognition and strand nicking mechanism. Biochemistry 20010731
Nucleotide binding domain 1 of the human retinal ABC transporter functions as a general ribonucleotidase. Biochemistry 20010727
Purine nucleoside phosphorylase from Mycobacterium tuberculosis. Analysis of inhibition by a transition-state analogue and dissection by parts. Biochemistry 20010727
Structures of purine nucleoside phosphorylase from Mycobacterium tuberculosis in complexes with immucillin-H and its pieces. Biochemistry 20010727
Investigation of the functional role of active site loop II in a hypoxanthine phosphoribosyltransferase. Biochimica et biophysica acta 20010727
Efficacy of the anti-CD22 recombinant immunotoxin BL22 in chemotherapy-resistant hairy-cell leukemia. The New England journal of medicine 20010726
Photoactivation of DNA thiobases as a potential novel therapeutic option. Current biology : CB 20010724
Diaminopurine-acridine heterodimers for specific recognition of abasic site containing DNA. Influence on the biological activity of the position of the linker on the purine ring. Bioorganic & medicinal chemistry letters 20010723
Nitric oxide inhibits methionine synthase activity in vivo and disrupts carbon flow through the folate pathway. The Journal of biological chemistry 20010720
Molecular genetics of nucleoside transporters in Leishmania and African trypanosomes. Biochemical pharmacology 20010715
Guanosine-induced increase in free cytosolic calcium concentration in mouse astrocytes in primary cultures: does it act on an A3 adenosine receptor? Journal of neuroscience research 20010715
Application of mixed partition-adsorption systems in high-performance liquid chromatography of purines and pyrimidines. Journal of chromatography. A 20010713
A transition-state analogue reduces protein dynamics in hypoxanthine-guanine phosphoribosyltransferase. Biochemistry 20010710
Misacylation and editing by Escherichia coli valyl-tRNA synthetase: evidence for two tRNA binding sites. Biochemistry 20010710
Equilibrative nucleoside transporters: mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins. Biochemistry 20010710
Purine but not pyrimidine nucleotides support rotation of F(1)-ATPase. The Journal of biological chemistry 20010706
Salmonella-based tumor-targeted cancer therapy: tumor amplified protein expression therapy (TAPET) for diagnostic imaging. Journal of controlled release : official journal of the Controlled Release Society 20010706
Requirement of de novo protein synthesis for aminopterin-induced apoptosis in a mouse myeloma cell line. Immunology letters 20010702
Changes in hippocampal adenosine efflux, ATP levels, and synaptic transmission induced by increased temperature. Synapse (New York, N.Y.) 20010701
Involvement of astrocytes in purine-mediated reparative processes in the brain. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20010701
Apical P2Y4 purinergic receptor controls K+ secretion by vestibular dark cell epithelium. American journal of physiology. Cell physiology 20010701
Pharmacokinetic studies of 2-amino-9-(3-acetoxymethyl-4-isopropoxycarbonyl-oxybut-1-yl)purine, an oral prodrug for the antiviral agent penciclovir. Drug metabolism and disposition: the biological fate of chemicals 20010701
Purine salvage to adenine nucleotides in different skeletal muscle fiber types. Journal of applied physiology (Bethesda, Md. : 1985) 20010701
Prognostic factors and response to fludarabine therapy in patients with Waldenström macroglobulinemia: results of United States intergroup trial (Southwest Oncology Group S9003). Blood 20010701
Structural basis for substrate specificities of cellular deoxyribonucleoside kinases. Nature structural biology 20010701
Crystallographic studies on damaged DNAs: III. N(4)-methoxycytosine can form both Watson-Crick type and wobbled base pairs in a B-form duplex. Journal of biochemistry 20010701
Release of ATP by a human retinal pigment epithelial cell line: potential for autocrine stimulation through subretinal space. The Journal of physiology 20010701
Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling. The Journal of clinical investigation 20010701
Expression, purification, and characterization of recombinant purine nucleoside phosphorylase from Escherichia coli. Protein expression and purification 20010701
Complete sequencing of mono-deprotonated peptide nucleic acids by sustained off-resonance irradiation collision-induced dissociation. Journal of the American Society for Mass Spectrometry 20010701
Purine N7 groups that are crucial to the interaction of Escherichia coli rnase P RNA with tRNA. RNA (New York, N.Y.) 20010701
trans-3,4-dihydroxy-anti-1,2-epoxy-1,2,3,4-tetrahydrodi- benz[a,j]acridine involvement in dibenz[a,j]acridine DNA adduct formation in mouse skin consistent with Ha-ras mutation patterns in tumors. Chemical research in toxicology 20010701
Effect of nitrogen source in high-concentrate, low-protein beef cattle diets on microbial fermentation studied in vivo and in vitro. Journal of animal science 20010701
[Combination therapy of IFN and ribavirin]. Nihon rinsho. Japanese journal of clinical medicine 20010701
Targeting of human Tmolt4 leukemic type II IMP dehydrogenase by cyclic imide related derivatives. Archiv der Pharmazie 20010701
[Pulmonary changes in rheumatoid arthritis]. Ceskoslovenska patologie 20010701
Purine receptor agonists protect the genome of plant and animal cells from clastogen damage. Bulletin of experimental biology and medicine 20010701
Apoptosis induces efflux of the mitochondrial matrix enzyme deoxyguanosine kinase. The Journal of biological chemistry 20010629
Comparative evaluation of Celsior solution versus Viaspan in a pig liver transplantation model. Transplantation 20010627
Behaviour of inorganic and organic cations in the Debye-Hückel layer of DNA. Journal of chromatography. A 20010622
Slow motion in the CAA*TTG sequence of a DNA decamer duplex studied by NMR. Biochemistry 20010619
Feedback inhibition of amidophosphoribosyltransferase regulates the rate of cell growth via purine nucleotide, DNA, and protein syntheses. The Journal of biological chemistry 20010615
A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle. FEBS letters 20010615
Physico-chemical studies on DNA triplexes containing an alternate third strand with a non-nucleotide linker. International journal of biological macromolecules 20010612
Intercalation of the (1R,2S,3R,4S)-N6-[1-(1,2,3,4-tetrahydro-2,3,4-trihydroxybenz[a]anthracenyl)]-2'-deoxyadenosyl adduct in the N-ras codon 61 sequence: DNA sequence effects. Biochemistry 20010612
Molecular genetics and structural biology of human MutT homolog, MTH1. Mutation research 20010602
Crystal structures of a ddATP-, ddTTP-, ddCTP, and ddGTP- trapped ternary complex of Klentaq1: insights into nucleotide incorporation and selectivity. Protein science : a publication of the Protein Society 20010601
A phase III, randomized, double-blind, placebo-controlled study of peldesine (BCX-34) cream as topical therapy for cutaneous T-cell lymphoma. Journal of the American Academy of Dermatology 20010601
Ray38p, a homolog of a purine motif triple-helical DNA-binding protein, Stm1p, is a ribosome-associated protein and dissociated from ribosomes prior to the induction of cycloheximide resistance in Candida maltosa. Biochemical and biophysical research communications 20010601
Biogenesis and function of peroxisomes and glycosomes. Molecular and biochemical parasitology 20010601
Involvement of a transformylase enzyme in siderophore synthesis in Pseudomonas aeruginosa. Microbiology (Reading, England) 20010601
Quinone isomers of the WS-5995 antibiotics: synthetic antitumor agents that inhibit macromolecule synthesis, block nucleoside transport, induce DNA fragmentation, and decrease the growth and viability of L1210 leukemic cells more effectively than ellagic acid and genistein in vitro. Anti-cancer drugs 20010601
Altered purine nucleotide degradation during exercise in patients with essential hypertension. Metabolism: clinical and experimental 20010601
Characterisation of an ATP diphosphohydrolase (Apyrase, EC 3.6.1.5) activity in Trichomonas vaginalis. International journal for parasitology 20010601
Purine nucleoside phosphorylase inhibitor BCX-1777 (Immucillin-H)--a novel potent and orally active immunosuppressive agent. International immunopharmacology 20010601
Synthesis and properties of triple helix-forming oligodeoxyribonucleotides containing 7-chloro-7-deaza-2'-deoxyguanosine. Bioorganic & medicinal chemistry 20010601
A purine-rich intronic element enhances alternative splicing of thyroid hormone receptor mRNA. RNA (New York, N.Y.) 20010601
Application of capillary electrophoresis in the analysis of novel synthetic dideoxynucleoside analogues with potential anti-HIV activity. Biomedical chromatography : BMC 20010601
Prostaglandins and nitric oxide mediate superoxide-induced myocardial contractile dysfunction in isolated rat hearts. Journal of molecular and cellular cardiology 20010601
Origins of life: a route to nanotechnology. Bio Systems 20010601
Diet and medication in the treatment of hyperuricemia in hypertensive patients. Arquivos brasileiros de cardiologia 20010601
Two novel mutations in a purine nucleoside phosphorylase (PNP)-deficient patient. Clinical genetics 20010601
Cardiac sympathetic afferent activation provoked by myocardial ischemia and reperfusion. Mechanisms and reflexes. Annals of the New York Academy of Sciences 20010601
Phase I and pharmacokinetic study of LY309887: a specific inhibitor of purine biosynthesis. Cancer chemotherapy and pharmacology 20010601
Treatment options in Waldenström's macroglobulinaemia: the role of the purine analogues. Expert opinion on pharmacotherapy 20010601
Infectious complications in chronic lymphoid malignancy. Current treatment options in oncology 20010601
Autoimmunity in chronic lymphocytic leukemia. Current treatment options in oncology 20010601
Immunotherapy of chronic lymphocytic leukemia. Expert review of anticancer therapy 20010601
Update on prophylaxis and therapy of infection in patients with chronic lymphocytic leukemia. Expert review of anticancer therapy 20010601
Hairy cell leukemia: treatment prospects. Expert review of anticancer therapy 20010601
Hybridization between oxy-peptide nucleic acids and DNAs: dependence of hybrid stabilities on the chain-lengths, types of base pairs, and the chain directions. Journal of the American Chemical Society 20010523
Molecular design of a new class of spin-labeled ribonucleosides with N-tert-butylaminoxyl radicals. The Journal of organic chemistry 20010518
Gcn2 mediates Gcn4 activation in response to glucose stimulation or UV radiation not via GCN4 translation. The Journal of biological chemistry 20010518
2'-Ribose-ferrocene oligonucleotides for electronic detection of nucleic acids. The Journal of organic chemistry 20010504
Characterization of nucleoside transport systems in cultured rat epididymal epithelium. American journal of physiology. Cell physiology 20010501
VX-497: a novel, selective IMPDH inhibitor and immunosuppressive agent. Journal of pharmaceutical sciences 20010501
Novel treatment strategies in chronic lymphocytic leukemia. Current oncology reports 20010501
Phosphorylation of uridine and cytidine nucleoside analogs by two human uridine-cytidine kinases. Molecular pharmacology 20010501
Structural determinants of adenophostin A activity at inositol trisphosphate receptors. Molecular pharmacology 20010501
Uridine receptor: discovery and its involvement in sleep mechanism. Sleep 20010501
Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis. Nature structural biology 20010501
Enhanced activity of the purine nucleotide cycle of the exercising muscle in patients with hyperthyroidism. The Journal of clinical endocrinology and metabolism 20010501
Effects of purine and pyrimidine nucleotides on intracellular Ca2+ in human eosinophils: activation of purinergic P2Y receptors. The Journal of allergy and clinical immunology 20010501
Fragmentation of electrospray-produced oligodeoxynucleotide ions adducted to metal ions. Journal of the American Society for Mass Spectrometry 20010501
9(R)-[6(R)-hydroxymethyl-1-oxa-4-thiacyclohexan-2-yl]hypoxanthine-water (4/3), a nucleoside analogue. Acta crystallographica. Section C, Crystal structure communications 20010501
Diminished adenosine A1 receptor expression on macrophages in brain and blood of patients with multiple sclerosis. Annals of neurology 20010501
Competence development by Haemophilus influenzae is regulated by the availability of nucleic acid precursors. Molecular microbiology 20010501
Evaluation of the mutagenic and genotoxic activities of anti-hepatitis B analogs of beta-L-adenosine by the Ames test and the Comet assay. Antiviral research 20010501
A possible prebiotic synthesis of purine, adenine, cytosine, and 4(3H)-pyrimidinone from formamide: implications for the origin of life. Bioorganic & medicinal chemistry 20010501
Chemical modification of aryl-1,2,3,6-tetrahydropyridinopyrimidine derivative to discover corticotropin-releasing factor(1) receptor antagonists: aryl-1,2,3,6-tetrahydropyridino-purine, -3H-1,2,3-triazolo[4,5-d)pyrimidine, -purin-8-one, and -7H-pyrrolo[2,3-d]pyrimidine derivatives. Bioorganic & medicinal chemistry 20010501
Does intensive treatment with high dose chlorambucil and prednisone as first line and cladribine as second line influence the survival of the patients with chronic lymphocytic leukemia? Leukemia & lymphoma 20010501
Pharmacological basis for cladribine resistance in a human acute T lymphoblastic leukaemia cell line selected for resistance to etoposide. British journal of haematology 20010501
Population pharmacokinetic modeling and model validation of a spicamycin derivative, KRN5500, in phase 1 study. Cancer chemotherapy and pharmacology 20010501
Neurologic aspects of adenylosuccinate lyase deficiency. Journal of child neurology 20010501
The activities of purine catabolizing enzymes in plasma and bronchial washing fluid in patients with lung cancer and pneumonia. Clinical biochemistry 20010501
gsk disruption leads to guanosine accumulation in Escherichia coli. Bioscience, biotechnology, and biochemistry 20010501
Pemetrexed disodium, a novel antifolate with multiple targets. The Lancet. Oncology 20010501
Pdx-1 is required for activation in vivo from a duodenum-specific enhancer. The Journal of biological chemistry 20010427
Lack of catalytic activity of a murine mRNA cytoplasmic serine hydroxymethyltransferase splice variant: evidence against alternative splicing as a regulatory mechanism. Biochemistry 20010424
A fluorescent sensor of the phosphorylation state of nucleoside diphosphate kinase and its use to monitor nucleoside diphosphate concentrations in real time. Biochemistry 20010424
The beta ' subunit of Escherichia coli RNA polymerase is not required for interaction with initiating nucleotide but is necessary for interaction with rifampicin. The Journal of biological chemistry 20010420
Binding of nucleotides to nucleoside diphosphate kinase: a calorimetric study. Biochemistry 20010417
Selective recognition of pyrimidine motif triplexes by a protein encoded by the bacterial transposon Tn7. Journal of molecular biology 20010413
Structure and function of a novel purine specific nucleoside hydrolase from Trypanosoma vivax. Journal of molecular biology 20010413
Solution conformation of an RNA--DNA hybrid duplex containing a pyrimidine RNA strand and a purine DNA strand. International journal of biological macromolecules 20010412
Effect on urinary bladder function and arterial blood pressure of the activation of putative purine receptors in brainstem areas. Autonomic neuroscience : basic & clinical 20010412
UDP hydrolase activity associated with the porcine liver annexin fraction. Biochimica et biophysica acta 20010403
15-mer DNA duplexes containing an abasic site are thermodynamically more stable with adjacent purines than with pyrimidines. Biochemistry 20010403
The effect of ABT-702, a novel adenosine kinase inhibitor, on the responses of spinal neurones following carrageenan inflammation and peripheral nerve injury. British journal of pharmacology 20010401
Local changes in GC/AT substitution biases and in crossover frequencies on Drosophila chromosomes. Molecular biology and evolution 20010401
Ascorbic acid changes the pattern of purine metabolism during germination of white spruce somatic embryos. Tree physiology 20010401
Functional characterization of a maize purine transporter by expression in Aspergillus nidulans. The Plant cell 20010401
Synthesis and characterization of nucleosides and oligonucleotides bearing adducts of butadiene epoxides on adenine n(6) and guanine n(2). Chemical research in toxicology 20010401
Analysis of peroxynitrite reactions with guanine, xanthine, and adenine nucleosides by high-pressure liquid chromatography with electrochemical detection: C8-nitration and -oxidation. Chemical research in toxicology 20010401
Microxine, a new cdc2 kinase inhibitor from the Australian marine sponge Microxina species. Journal of natural products 20010401
Determination of purine compounds in carotid artery plaque by liquid chromatography electrospray ionization tandem mass spectrometry. Journal of mass spectrometry : JMS 20010401
Proteome and transcriptome based analysis of Bacillus subtilis cells overproducing an insoluble heterologous protein. Applied microbiology and biotechnology 20010401
Identification and characterization of trypanocides by functional expression of an adenosine transporter from Trypanosoma brucei in yeast. Journal of molecular medicine (Berlin, Germany) 20010401
The analysis of human amniotic fluid using capillary electrophoresis. Electrophoresis 20010401
Tmolt4 leukemic type II isoform of IMP dehydrogenase as a target for 1,2,4-triazolidine-3,5-diones, 1-(1-(3-methylphenyl)ethylidineamino)-4,4-diethyl-3,5-azetidinediones, 3,5-isoxazolidinediones, and 4,4-disubstituted-3,5-pyrazolidinediones. Archiv der Pharmazie 20010401
Extracellular ATP potentiates steroidogenic effect of adrenocorticotropic hormone in bovine adrenocortical fasciculata cells. Japanese journal of pharmacology 20010401
A unique surface membrane anchored purine-salvage enzyme is conserved among a group of primitive eukaryotic human pathogens. Molecular and cellular biochemistry 20010401
Activity of pemetrexed (ALIMTA, multitargeted antifolate, LY231514) in metastatic breast cancer patients previously treated with an anthracycline and a taxane: an interim analysis. Clinical breast cancer 20010401
CyaG, a novel cyanobacterial adenylyl cyclase and a possible ancestor of mammalian guanylyl cyclases. The Journal of biological chemistry 20010330
Activation of glutamate uptake by guanosine in primary astrocyte cultures. Neuroreport 20010326
Structures of bovine glutamate dehydrogenase complexes elucidate the mechanism of purine regulation. Journal of molecular biology 20010323
Reflections on the purinergic hypothesis: the Burnstock Festschrift in the millennial year. Autonomic neuroscience : basic & clinical 20010323
7-Methylxanthine methyltransferase of coffee plants. Gene isolation and enzymatic properties. The Journal of biological chemistry 20010316
Macrochelation, cyclometallation and G-quartet formation: N3- and C8-bound PdII complexes of adenine and guanine. Chemistry (Weinheim an der Bergstrasse, Germany) 20010316
Role of adenosine kinase in Saccharomyces cerevisiae: identification of the ADO1 gene and study of the mutant phenotypes. Yeast (Chichester, England) 20010315
Protective effect of various antioxidants on the toxicity of sulphur mustard administered to mice by inhalation or percutaneous routes. Chemico-biological interactions 20010314
The role for an invariant aspartic acid in hypoxanthine phosphoribosyltransferases is examined using saturation mutagenesis, functional analysis, and X-ray crystallography. Biochemistry 20010306
Adenosine increases ventilation rate, cardiac performance and haemolymph velocity in the American lobster Homarus americanus. The Journal of experimental biology 20010301
Sugar-modified nucleosides in past 10 years, a review. Current medicinal chemistry 20010301
Na+ reabsorption in cultured rat epididymal epithelium via the Na+/nucleoside cotransporter. Biology of reproduction 20010301
Adenosine deaminase: functional implications and different classes of inhibitors. Medicinal research reviews 20010301
New immunosuppressive drugs: an update. Current opinion in urology 20010301
The protective effect of acadesine on lung ischemia-reperfusion injury. Anesthesia and analgesia 20010301
UCP1: the only protein able to mediate adaptive non-shivering thermogenesis and metabolic inefficiency. Biochimica et biophysica acta 20010301
Cell cycle in the fucus zygote parallels a somatic cell cycle but displays a unique translational regulation of cyclin-dependent kinases. The Plant cell 20010301
Gas-phase hydrogen/deuterium exchange of positively charged mononucleotides by use of Fourier-transform ion cyclotron resonance mass spectrometry. Journal of the American Society for Mass Spectrometry 20010301
Active intestinal absorption of nucleosides by Na+-dependent transport across the brush border membrane in cows. Journal of dairy science 20010301
Nucleoside transporters of parasitic protozoa. Trends in parasitology 20010301
The spectrum of hypoxanthine-guanine phosphoribosyltransferase (HPRT) deficiency. Clinical experience based on 22 patients from 18 Spanish families. Medicine 20010301
Effect of chemical modifications of cytosine and guanine in a CpG-motif of oligonucleotides: structure-immunostimulatory activity relationships. Bioorganic & medicinal chemistry 20010301
Effective treatment with rituximab in a patient with refractory prolymphocytoid transformed B-chronic lymphocytic leukemia and Evans syndrome. Annals of hematology 20010301
The release of the substrate for xanthine oxidase in hypertensive patients was suppressed by angiotensin converting enzyme inhibitors and alpha1-blockers. Journal of hypertension 20010301
Intramolecular stacking interactions in ternary copper(II) complexes formed with 2,2'-bipyridine or 1,10-phenanthroline and 9-(4-phosphonobutyl)adenine (dPMEA), the carba relative of the antiviral nucleotide analogue 9. Journal of inorganic biochemistry 20010301
Investigation of various genotype characteristics for inosine accumulation in Escherichia coli W3110. Bioscience, biotechnology, and biochemistry 20010301
An extended structural signature for the tRNA anticodon loop. RNA (New York, N.Y.) 20010301
Immunostimulant oxidized beta-glucan conjugates. International immunopharmacology 20010301
Role of the Escherichia coli and human DNA glycosylases that remove 5-formyluracil from DNA in the prevention of mutations. Journal of radiation research 20010301
HF-STEX and RASSCF calculations on nitrogen K-shell X-ray absorption of purine base and its derivative. Journal of synchrotron radiation 20010301
DAPD (Emory University/Triangle Pharmaceuticals/Abbott Laboratories). Current opinion in investigational drugs (London, England : 2000) 20010301
Analysis of exonic splicing enhancers in the mouse gonadotropin-releasing hormone (GnRH) gene. Molecular and cellular endocrinology 20010227
Metal ion-directed cooperative triple helix formation of glutamic acid--oligonucleotide conjugate. Journal of the American Chemical Society 20010227
Eosinophil peroxidase catalyzes bromination of free nucleosides and double-stranded DNA. Biochemistry 20010220
Importance of specific nucleotides in the folding of the natural form of the hairpin ribozyme. Biochemistry 20010220
Oxidative changes in brain pyridine nucleotides and neuroprotection using nicotinamide. Biochimica et biophysica acta 20010216
In situ kinetic characterization of methylthioadenosine transport by the adenosine transporter (P2) of the African Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense. Biochemical pharmacology 20010215
A kinetic study on the interaction of deprotonated purine radical cations with amino acids and model peptides. Biophysical chemistry 20010215
A quantitative model for allosteric control of purine reduction by murine ribonucleotide reductase. Biochemistry 20010213
Determination of urinary methylated purine pattern by high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications 20010210
Melphalan and purine analog-containing preparative regimens: reduced-intensity conditioning for patients with hematologic malignancies undergoing allogeneic progenitor cell transplantation. Blood 20010201
A purF mutant of Mycobacterium smegmatis has impaired survival during oxygen-starved stationary phase. Microbiology (Reading, England) 20010201
Analysis of purine- and pyrimidine-induced vascular responses in the isolated rat cerebral arteriole. American journal of physiology. Heart and circulatory physiology 20010201
Extracellular ATP induces a distorted maturation of dendritic cells and inhibits their capacity to initiate Th1 responses. Journal of immunology (Baltimore, Md. : 1950) 20010201
Mutation of Gln125 to Asn selectively abolishes the thymidylate kinase activity of herpes simplex virus type 1 thymidine kinase. Molecular pharmacology 20010201
A novel proton-dependent nucleoside transporter, CeCNT3, from Caenorhabditis elegans. Molecular pharmacology 20010201
The evolution of ribonucleotide reduction revisited. Trends in biochemical sciences 20010201
The folate cycle and disease in humans. Kidney international. Supplement 20010201
Annexins as nucleotide-binding proteins: facts and speculations. BioEssays : news and reviews in molecular, cellular and developmental biology 20010201
Structure-function relationships in UCP1, UCP2 and chimeras: EPR analysis and retinoic acid activation of UCP2. European journal of biochemistry 20010201
Assessment of Leishmania promastigote growth in vitro by means of nucleoside hydrolase activity determination. Parasitology research 20010201
Purine and pyrimidine nucleotide-sensitive phospholipase A(2) in ampulla from frog semicircular canal. American journal of physiology. Regulatory, integrative and comparative physiology 20010201
A novel assay for determination of diadenosine polyphosphates in human platelets: studies in normotensive subjects and in patients with essential hypertension. Journal of hypertension 20010201
Sequential fluorescence in situ hybridization analyses for trisomy 12 in chronic leukemic B-cell disorders. Haematologica 20010201
Effect of furosemide on renal excretion of oxypurinol and purine bases. Metabolism: clinical and experimental 20010201
[Pharmacological profiles of mycophenolate mofetil (CellCept), a new immunosuppressive agent]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010201
Interactions between 2-fluoroadenine 9-beta-D-arabinofuranoside and the kinase inhibitor UCN-01 in human leukemia and lymphoma cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20010201
Interstitial brain adenosine and xanthine increase during jugular venous oxygen desaturations in humans after traumatic brain injury. Critical care medicine 20010201
Characterization of DNA damage at purine residues in oligonucleotides and calf thymus DNA induced by the mutagen 1-nitrosoindole-3-acetonitrile. Chemical research in toxicology 20010201
Uric acid mediates photodynamic inactivation of caprine alpha-2-macroglobulin. Free radical research 20010201
Regulation of hisHF transcription of Aspergillus nidulans by adenine and amino acid limitation. Fungal genetics and biology : FG & B 20010201
Disturbance of purine nucleotide metabolism: a possible early key event in development of intestinal damage induced by chemotherapy. Digestive diseases and sciences 20010201
Blood purine and energy status in rats with colitis. Digestive diseases and sciences 20010201
Inhibition of peroxynitrite-induced dityrosine formation with oxidized and reduced thiols, nitric oxide donors, and purine derivatives. Antioxidants & redox signaling 20010201
Candida tropicalis and Penicillium marneffei mixed fungaemia in a patient with Waldenström's macroglobulinaemia. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20010201
Intra- and intermolecular triplex DNA formation in the murine c-myb proto-oncogene promoter are inhibited by mithramycin. Biological chemistry 20010201
Second primary tumors and immune phenomena after fludarabine or 2-chloro-2'-deoxyadenosine treatment. Leukemia & lymphoma 20010201
Cladribine in the treatment of chronic lymphocytic leukemia. Leukemia & lymphoma 20010201
Cytogenetic analysis oxidative damage in lymphocytes of Parkinson's disease patients. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20010201
The current state of extracorporeal haemorheotherapy: from haemodilution via cascadefiltration to rheohaemapheresis. Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 20010201
Cangrelor AstraZeneca. Current opinion in investigational drugs (London, England : 2000) 20010201
A new experimental system for study on adaptive mutations. Science in China. Series C, Life sciences 20010201
Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis. Biochemistry 20010130
Probing structure and dynamics of DNA with 2-aminopurine: effects of local environment on fluorescence. Biochemistry 20010130
Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). The Journal of biological chemistry 20010126
Role of conserved nucleotides in building the 16 S rRNA binding site for ribosomal protein S15. Journal of molecular biology 20010126
Purine nucleotide catabolism in rat liver: labelling of uric acid and allantoin after treatment with oxonic acid and allopurinol. Life sciences 20010126
The effect of folate deficiency on the cytotoxic and mutagenic responses to ethyl methanesulfonate in human lymphoblastoid cell lines that differ in p53 status. Mutation research 20010125
Non-oxidative mechanisms are responsible for the induction of mutagenesis by reduction of Cr(VI) with cysteine: role of ternary DNA adducts in Cr(III)-dependent mutagenesis. Biochemistry 20010116
Binding site of Fe3+ at purine of ATP as studied by NMR. Journal of inorganic biochemistry 20010115
The RihA, RihB, and RihC ribonucleoside hydrolases of Escherichia coli. Substrate specificity, gene expression, and regulation. The Journal of biological chemistry 20010112
Interaction of Escherichia coli purine nucleoside phosphorylase (PNP) with the cationic and zwitterionic forms of the fluorescent substrate N(7)-methylguanosine. Biochimica et biophysica acta 20010112
Xanthine dehydrogenase from Pseudomonas putida 86: specificity, oxidation-reduction potentials of its redox-active centers, and first EPR characterization. Biochimica et biophysica acta 20010112
Cloning of a novel isoform of the mouse NBMPR-sensitive equilibrative nucleoside transporter (ENT1) lacking a putative phosphorylation site. Gene 20010110
The characteristics of nucleobase transport and metabolism by the perfused sheep choroid plexus. Brain research 20010105
The main products of the low molecular mass fraction in the venom of the spider Latrodectus menavodi. Toxicon : official journal of the International Society on Toxinology 20010101
Properties of native P2X receptors in rat trigeminal mesencephalic nucleus neurones: lack of correlation with known, heterologously expressed P2X receptors. Neuropharmacology 20010101
Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells. Molecular pharmacology 20010101
The role of uric acid in protection against peroxynitrite-mediated pathology. Medical hypotheses 20010101
Calf spleen purine nucleoside phosphorylase: structure of its ternary complex with an N(7)-acycloguanosine inhibitor and a phosphate anion. Acta crystallographica. Section D, Biological crystallography 20010101
Metabolic fate of extracellular NAD in human skin fibroblasts. Journal of cellular biochemistry 20010101
Comparison of negative and positive ion electrospray tandem mass spectrometry for the liquid chromatography tandem mass spectrometry analysis of oxidized deoxynucleosides. Journal of the American Society for Mass Spectrometry 20010101
Inosine-5'-monophosphate dehydrogenase is required for mitogenic competence of transformed pancreatic beta cells. Endocrinology 20010101
Purines inhibit poly(ADP-ribose) polymerase activation and modulate oxidant-induced cell death. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101
Effect of the tropical forage calliandra on microbial protein synthesis and ecology in the rumen. Journal of applied microbiology 20010101
Sequence-specific detection of aristolochic acid-DNA adducts in the human p53 gene by terminal transferase-dependent PCR. Carcinogenesis 20010101
Characterization of a triplex DNA-binding protein encoded by an alternative reading frame of loricrin. European journal of biochemistry 20010101
Unexpectedly high incidence of hypoplastic/aplastic foci in bone marrow biopsies of hairy cell leukemia patients in remission following 2-chlorodeoxyadenosine therapy. European journal of haematology 20010101
Use of molecular beacons to verify that the serine hydroxymethyltransferase pseudogene SHMT-ps1 is unique to the order Primates. Genome biology 20010101
Structure-activity relationships for a collection of structurally diverse inhibitors of purine nucleoside phosphorylase. Chemical & pharmaceutical bulletin 20010101
6-mercaptopurine dosage and pharmacokinetics influence the degree of bone marrow toxicity following high-dose methotrexate in children with acute lymphoblastic leukemia. Leukemia 20010101
beta-Amyloid protein induces the formation of purine dimers in cellular DNA. Journal of cellular biochemistry 20010101
Prebiotic synthesis of nucleotides. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20010101
Genome-wide analysis of protein-DNA interactions in living cells. Genome biology 20010101
2-chlorodeoxyadenosine (cladribine) in the treatment of hairy cell leukemia. Zhonghua yi xue za zhi = Chinese medical journal; Free China ed 20010101
Azathioprine therapy for patients with systemic lupus erythematosus. Lupus 20010101
Treatment of systemic lupus erythematosus with mycophenolate mofetil. Lupus 20010101
Comparative sequence analysis of plasmids pME2001 and pME2200 of methanothermobacter marburgensis strains Marburg and ZH3. Plasmid 20010101
A concomitant ATP-depleting strategy markedly enhances anticancer agent activity. Apoptosis : an international journal on programmed cell death 20010101
Photolithographic synthesis of high-density oligonucleotide arrays. Methods in molecular biology (Clifton, N.J.) 20010101
New aspects on the pathogenesis, diagnostic procedures, and therapeutic management of chronic lymphocytic leukemia. International journal of hematology 20010101
The nitrilase superfamily: classification, structure and function. Genome biology 20010101
Recent molecular advances in studies of the concentrative Na+-dependent nucleoside transporter (CNT) family: identification and characterization of novel human and mouse proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib). Molecular membrane biology 20010101
Complex regulation of nucleoside transporter expression in epithelial and immune system cells. Molecular membrane biology 20010101
Gouty arthritis: not just a big toe problem. Geriatric nursing (New York, N.Y.) 20010101
Purine analogs as CDK enzyme inhibitory agents: a survey and QSAR analysis. Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20010101
[Purine biosynthesis de novo in the retina: evolutionary aspects]. Zhurnal evoliutsionnoi biokhimii i fiziologii 20010101
Uncoupling proteins in mitochondria of plants and some microorganisms. Acta biochimica Polonica 20010101
Adenine toxicity and transport in the moderately halophilic eubacterium Halomonas elongata. Journal of basic microbiology 20010101
A systematic overview of chemotherapy effects in indolent non-Hodgkin's lymphoma. Acta oncologica (Stockholm, Sweden) 20010101
A systematic overview of chemotherapy effects in B-cell chronic lymphocytic leukaemia. Acta oncologica (Stockholm, Sweden) 20010101
Proteins, nucleic acids and genetic codes. Rivista di biologia 20010101
[Post-radiation changes in kinetic parameters of purine-catabolizing enzymes in rat blood serum after combined action of external and internal irradiation caused by 137Cs]. Radiatsionnaia biologiia, radioecologiia 20010101
Angiotensin-induced enhancement of excitatory junction potentials evoked by periarteriolar nerve stimulation and vasoconstriction in rat mesenteric arteries are both mediated by the angiotensin AT1 receptor. Pharmacology 20010101
[Use of plasmapheresis for correction of metabolic disorders in patients with surgical sepsis]. Anesteziologiia i reanimatologiia 20010101
[Adenine reutilization as a cause of increased ATP concentration in erythrocytes of patients with chronic renal failure]. Polskie Archiwum Medycyny Wewnetrznej 20010101
[Urine fibrinolytic activity as an indicator of kidney damage in uric acid metabolic imbalance]. Terapevticheskii arkhiv 20010101
Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management. Drug safety 20010101
Pemetrexed disodium: a novel antifolate clinically active against multiple solid tumors. The oncologist 20010101
Gene targeting via triple-helix formation. Progress in nucleic acid research and molecular biology 20010101
Phosphoribosylpyrophosphate synthetase and the regulation of phosphoribosylpyrophosphate production in human cells. Progress in nucleic acid research and molecular biology 20010101
[Experimental study of radiosensitizing effect of analogs of purines and pyrimidine bases in cultured HeLa cells]. Vestnik Rossiiskoi akademii meditsinskikh nauk 20010101
DNA substrates containing defined oxidative base lesions and their application to study substrate specificities of base excision repair enzymes. Progress in nucleic acid research and molecular biology 20010101
Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage. Progress in nucleic acid research and molecular biology 20010101
Autoimmune thrombocytopenia associated with the first cycle of fludarabine therapy in the treatment of relapsed non-Hodgkin's lymphoma. Clinical oncology (Royal College of Radiologists (Great Britain)) 20010101
Altered intracellular purine nucleotides in gamma-irradiated red blood cell concentrates. Vox sanguinis 20010101
Potent in vitro anticancer activities of ring-expanded ('fat') nucleosides containing the imidazo[4,5-e][1,3]diazepine ring system. Nucleosides, nucleotides & nucleic acids 20010101
Synthesis and in vitro antiviral activity evaluation of 9-(2-azido-2,3-dideoxy-beta-D-threo-pentofuranosyl)adenine derivatives. Nucleosides, nucleotides & nucleic acids 20010101
Synthesis and antiviral activity of novel exomethylene cyclopropyl nucleosides. Nucleosides, nucleotides & nucleic acids 20010101
The design and synthesis of purine inhibitors of CDK2. III. Nucleosides, nucleotides & nucleic acids 20010101
Synthesis of 8-amino and 8-substituted amino derivatives of acyclic purine nucleoside and nucleotide analogs. Alkylation of 8-substituted purine bases. Nucleosides, nucleotides & nucleic acids 20010101
Synthesis and evaluation of antiviral activity of higher homologues of xylo-carbocyclic nucleosides. Nucleosides, nucleotides & nucleic acids 20010101
Synthesis and base pairing properties of 9-deazapurine N7-nucleosides in oligonucleotide duplexes and triplexes. Nucleosides, nucleotides & nucleic acids 20010101
Large-scale manufacturing of all four 2'-deoxynucleosides via novel strategies including a chemo-enzymatic process. Nucleosides, nucleotides & nucleic acids 20010101
Ribose modified nucleosides and nucleotides as ligands for purine receptors. Nucleosides, nucleotides & nucleic acids 20010101
Synthesis and antiviral activity of D- and L-2'-azido-2',3'-dideoxy-4'-thiopyrimidine and purine nucleosides. Nucleosides, nucleotides & nucleic acids 20010101
Synthesis and biological activity of 4'-C-hydroxymethyl-2'-fluoro-D-arabinofuranosylpurine nucleosides. Nucleosides, nucleotides & nucleic acids 20010101
Cell imaging and morphology: application to studies of inherited purine metabolic disorders. Pharmacology & therapeutics 20010101
[Disorders of purine metabolism and the antioxidant system in obstetrical-gynecologic sepsis]. Anesteziologiia i reanimatologiia 20010101
Immunoreactivity to P2X(6) receptors in the rat hypothalamo-neurohypophysial system: an ultrastructural study with extravidin and colloidal gold-silver labelling. Neuroscience 20010101
Genomic-scale measurement of mRNA turnover and the mechanisms of action of the anti-cancer drug flavopiridol. Genome biology 20010101
An atypical case of primary renal tubular hypokalaemic metabolic alkalosis with chronic tophaceous gout. Clinical rheumatology 20010101
Purine and pyrimidine nucleoside analogs. Cancer chemotherapy and biological response modifiers 20010101
Alveolar epithelial type II cell: defender of the alveolus revisited. Respiratory research 20010101
The heterotopic tracheal allograft as an animal model of obliterative bronchiolitis. Respiratory research 20010101
Pharmacology of airway afferent nerve activity. Respiratory research 20010101
Poly purine.pyrimidine sequences upstream of the beta-galactosidase gene affect gene expression in Saccharomyces cerevisiae. BMC molecular biology 20010101
Xanthine oxidase catalyzes the synthesis of retinoic acid. Journal of enzyme inhibition 20010101
Fulminant hepatic failure secondary to adenovirus following fludarabine-based chemotherapy for non-Hodgkin's lymphoma. Leukemia & lymphoma 20010101
Perturbations in the impact of mutational activity on Vlambda genes in systemic lupus erythematosus. Arthritis research 20010101
Sequence-specific DNA cleavage by dipeptides disubstituted with chlorambucil and 2,6-dimethoxyhydroquinone-3-mercaptoacetic acid. Bioconjugate chemistry 20010101
Prediction of co-regulated genes in Bacillus subtilis on the basis of upstream elements conserved across three closely related species. Genome biology 20010101
Optimality of the genetic code with respect to protein stability and amino-acid frequencies. Genome biology 20010101
Frequencies and relative levels of clustered damages in DNA exposed to gamma rays in radioquenching vs. nonradioquenching conditions. Environmental and molecular mutagenesis 20010101
Effect of 5-aminoimidazole-4-carboxamide riboside (AICA-r) on isolated thoracic aorta responses in streptozotocin-diabetic rats. Journal of basic and clinical physiology and pharmacology 20010101
Base excision repair processing of radiation-induced clustered DNA lesions. Radiation protection dosimetry 20010101
[Structural organization of the human genome: distribution of nucleotides, Alu-repeats and exons in chromosomes 21 and 22]. Molekuliarnaia biologiia 20010101
Adenosine deaminase activity and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus. Clinical rheumatology 20010101
Clustered DNA damages induced by high and low LET radiation, including heavy ions. Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB) 20010101
Effect of level and origin of rumen degradable nitrogen on rumen microbial growth and nitrogen utilisation efficiency of animals fed maize silage at maintenance. Reproduction, nutrition, development 20010101
Hyperuricemia and gout in thyroid endocrine disorders. Clinical and experimental rheumatology 20010101
The mitochondrial uncoupling protein UCP1: a gated pore. IUBMB life 20010101
The role of non-myeloablative conditioning in allowing engraftment of allogeneic hematopoietic cells for correction of genetic disorders and for immunotherapy of leukemia. Annals of transplantation 20010101
Complete nucleotide sequence and the genome organization of Patchouli mild mosaic virus RNA1. Intervirology 20010101
[Molecular genetic features of Vibrio cholerae classica strains, that caused the Asiatic cholera epidemic in Russian in 1942]. Molekuliarnaia genetika, mikrobiologiia i virusologiia 20010101
A theoretical investigation on the effect of remote amino groups in hydrogen bonding of nucleic acids. Biopolymers 20010101
Antileukemic activity of synthetic daunomycinone derivatives bearing modifications in the glycosidic moiety. Anticancer research 20010101
The role of ring D in the antitumour antibiotic streptonigrin: metal complexation, DNA binding and topoisomerase inhibition by ABC ring analogues of streptonigrin. Anti-cancer drug design 20010101
[Specific interactions of isoguanine with the neutral and deprotonated carboxylic group of amino acids: results of model quantum chemical calculations]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20010101
A purine-sensitive mechanism regulates the molecular program for axon growth. Restorative neurology and neuroscience 20010101
Effect of N fertilisation rate, energy supplementation and supplementation strategy on efficiency of N utilisation in the sheep rumen. Archiv fur Tierernahrung 20010101
Purine nucleotide metabolism in cultured neurons and astroglia from HPRT-deficient knockout mice. The Italian journal of biochemistry 20010101
Biochemical and metabolic peculiarities of some parasites availing as targets for therapy. Le Journal medical libanais. The Lebanese medical journal 20010101
Fate of prebiotic adenine. Astrobiology 20010101
Effect of temperature on the adsorption of adenine. Astrobiology 20010101
Efforts toward creating unnatural base pairs for an expanded genetic code. Nucleic acids research. Supplement (2001) 20010101
Adduct formation between oxanine and amine derivatives. Nucleic acids research. Supplement (2001) 20010101
Synthesis and properties of a new class of nucleosides with spin source. Nucleic acids research. Supplement (2001) 20010101
Synthetic study of guanofosfocin. Synthesis of 8-(mannopyranosyloxy)inosine derivative. Nucleic acids research. Supplement (2001) 20010101
X-ray analyses of DNA dodecamers containing 2'-deoxy-5-formyluridine. Nucleic acids research. Supplement (2001) 20010101
Promotion of duplex and triplex DNA formation by polycation comb-type copolymers. Methods in molecular medicine 20010101
Adenine-induced selective apoptosis toward HIV chronically infected cells in vitro. Biochemical and biophysical research communications 20000714
Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. Biochemical pharmacology 19951109
2-amino-9-(3-azido-2,3-dideoxy-beta-D-erythro-pentofuranosyl)-6-substituted-9H-purines: synthesis and anti-HIV activity. Bioorganic & medicinal chemistry 19950401
A STUDY OF THE CROSS-REACTIVITY OF ANTIPURIN-6-OYL SERUM WITH DEOXYRIBONUCLEIC ACID (DNA). The Journal of experimental medicine 19650101
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