Home Halogens 4-Amino-7-chloroquinoline

4-Amino-7-chloroquinoline

CAS No.:
1198-40-9
Catalog Number:
AG000PNW
Molecular Formula:
C9H7ClN2
Molecular Weight:
178.6183
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
In Stock USA
United States
$116
- +
1g
95%
In Stock USA
United States
$125
- +
5g
95%
In Stock USA
United States
$432
- +
10g
95%
In Stock USA
United States
$800
- +
50g
In Stock USA
United States
$3269
- +
Product Description
Catalog Number:
AG000PNW
Chemical Name:
4-Amino-7-chloroquinoline
CAS Number:
1198-40-9
Molecular Formula:
C9H7ClN2
Molecular Weight:
178.6183
MDL Number:
MFCD00828822
IUPAC Name:
7-chloroquinolin-4-amine
InChI:
InChI=1S/C9H7ClN2/c10-6-1-2-7-8(11)3-4-12-9(7)5-6/h1-5H,(H2,11,12)
InChI Key:
NDRZSRWMMUGOBP-UHFFFAOYSA-N
SMILES:
Clc1ccc2c(c1)nccc2N
NSC Number:
13
Properties
Complexity:
163  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
178.03g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
178.619g/mol
Monoisotopic Mass:
178.03g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
38.9A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.3  
Literature
Title Journal
Synthesis and comparison of antiplasmodial activity of (+), (-) and racemic 7-chloro-4-(N-lupinyl)aminoquinoline. Bioorganic & medicinal chemistry 20121001
Synthesis and antiplasmodial activity of new heteroaryl derivatives of 7-chloro-4-aminoquinoline. Bioorganic & medicinal chemistry 20121001
Cinnamic acid/chloroquinoline conjugates as potent agents against chloroquine-resistant Plasmodium falciparum. ChemMedChem 20120901
The synthesis of 2,5-bis(4-amidinophenyl)thiophene derivatives providing submicromolar-range inhibition of the botulinum neurotoxin serotype A metalloprotease. European journal of medicinal chemistry 20120701
Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides. Journal of medicinal chemistry 20120412
Antimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasites. PloS one 20120101
Synthesis of 4-aminoquinoline analogues and their platinum(II) complexes as new antileishmanial and antitubercular agents. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110601
Huprines as a new family of dual acting trypanocidal-antiplasmodial agents. Bioorganic & medicinal chemistry 20110301
Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations. Malaria journal 20110101
Synthesis and anti-prion activity evaluation of aminoquinoline analogues. European journal of medicinal chemistry 20101101
Synthesis, antimalarial activity, and cellular toxicity of new arylpyrrolylaminoquinolines. Bioorganic & medicinal chemistry 20100915
Structural modifications of quinoline-based antimalarial agents: Recent developments. Journal of pharmacy & bioallied sciences 20100101
Synthesis and in vitro antitubercular activity of a series of quinoline derivatives. Bioorganic & medicinal chemistry 20090215
Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas. Bioorganic & medicinal chemistry 20090101
New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton. Journal of medicinal chemistry 20081009
Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A. Journal of medicinal chemistry 20080814
Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline. Bioorganic & medicinal chemistry letters 20080701
Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines. Journal of medicinal chemistry 20080410
Metallocene antimalarials: the continuing quest. Metal-based drugs 20080101
Immunohistochemical demonstration of the distribution of chloroquine (CQ) and its metabolites in CQ-poisoned mice. Archives of toxicology 20070701
A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease. Journal of medicinal chemistry 20070503
4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity. Bioorganic & medicinal chemistry 20050915
Synergistic interaction of a chloroquine metabolite with chloroquine against drug-resistant malaria parasites. Biochemical pharmacology 20040401
Properties