4-Amino-7-chloroquinoline
Title | Journal |
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Synthesis and comparison of antiplasmodial activity of (+), (-) and racemic 7-chloro-4-(N-lupinyl)aminoquinoline. | Bioorganic & medicinal chemistry 20121001 |
Synthesis and antiplasmodial activity of new heteroaryl derivatives of 7-chloro-4-aminoquinoline. | Bioorganic & medicinal chemistry 20121001 |
Cinnamic acid/chloroquinoline conjugates as potent agents against chloroquine-resistant Plasmodium falciparum. | ChemMedChem 20120901 |
The synthesis of 2,5-bis(4-amidinophenyl)thiophene derivatives providing submicromolar-range inhibition of the botulinum neurotoxin serotype A metalloprotease. | European journal of medicinal chemistry 20120701 |
Design, synthesis, and in vitro activity of novel 2'-O-substituted 15-membered azalides. | Journal of medicinal chemistry 20120412 |
Antimalarial activity and mechanisms of action of two novel 4-aminoquinolines against chloroquine-resistant parasites. | PloS one 20120101 |
Synthesis of 4-aminoquinoline analogues and their platinum(II) complexes as new antileishmanial and antitubercular agents. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110601 |
Huprines as a new family of dual acting trypanocidal-antiplasmodial agents. | Bioorganic & medicinal chemistry 20110301 |
Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations. | Malaria journal 20110101 |
Synthesis and anti-prion activity evaluation of aminoquinoline analogues. | European journal of medicinal chemistry 20101101 |
Synthesis, antimalarial activity, and cellular toxicity of new arylpyrrolylaminoquinolines. | Bioorganic & medicinal chemistry 20100915 |
Structural modifications of quinoline-based antimalarial agents: Recent developments. | Journal of pharmacy & bioallied sciences 20100101 |
Synthesis and in vitro antitubercular activity of a series of quinoline derivatives. | Bioorganic & medicinal chemistry 20090215 |
Synthesis and antimalarial activity of new 4-amino-7-chloroquinolyl amides, sulfonamides, ureas and thioureas. | Bioorganic & medicinal chemistry 20090101 |
New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton. | Journal of medicinal chemistry 20081009 |
Novel 4-aminoquinolines active against chloroquine-resistant and sensitive P. falciparum strains that also inhibit botulinum serotype A. | Journal of medicinal chemistry 20080814 |
Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline. | Bioorganic & medicinal chemistry letters 20080701 |
Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines. | Journal of medicinal chemistry 20080410 |
Metallocene antimalarials: the continuing quest. | Metal-based drugs 20080101 |
Immunohistochemical demonstration of the distribution of chloroquine (CQ) and its metabolites in CQ-poisoned mice. | Archives of toxicology 20070701 |
A refined pharmacophore identifies potent 4-amino-7-chloroquinoline-based inhibitors of the botulinum neurotoxin serotype A metalloprotease. | Journal of medicinal chemistry 20070503 |
4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity. | Bioorganic & medicinal chemistry 20050915 |
Synergistic interaction of a chloroquine metabolite with chloroquine against drug-resistant malaria parasites. | Biochemical pharmacology 20040401 |