CD-437
| Title | Journal |
|---|---|
| Human Adenine Nucleotide Translocase (ANT) Modulators Identified by High-Throughput Screening of Transgenic Yeast. | Journal of biomolecular screening 20160401 |
| Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
| Analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. 2. Impact of 3-chloro group replacement on inhibition of proliferation and induction of apoptosis of leukemia and cancer cell lines. | Journal of medicinal chemistry 20120112 |
| A pleiotropic role for the orphan nuclear receptor small heterodimer partner in lipid homeostasis and metabolic pathways. | Journal of lipids 20120101 |
| The retinoid, 6-[3-adamantyl-4-hydroxyphenyl]-2-napthalene carboxylic acid, controls proliferative, morphological, and inflammatory responses involved in microglial activation without cytotoxic effects. | Neuroscience 20110929 |
| Heteroatom-substituted analogues of orphan nuclear receptor small heterodimer partner ligand and apoptosis inducer (E)-4-[3-(1-Adamantyl)-4-hydroxyphenyl]-3-chlorocinnamic acid. | Journal of medicinal chemistry 20110609 |
| Molecular recognition and enhancement of aqueous solubility and bioactivity of CD437 by β-cyclodextrin. | Bioorganic & medicinal chemistry letters 20110115 |
| Activation of NAG-1 via JNK signaling revealed an isochaihulactone-triggered cell death in human LNCaP prostate cancer cells. | BMC cancer 20110101 |
| Mitochondrial peroxiredoxin III is a potential target for cancer therapy. | International journal of molecular sciences 20110101 |
| Retinoic acid receptor-α signalling antagonizes both intracellular and extracellular amyloid-β production and prevents neuronal cell death caused by amyloid-β. | The European journal of neuroscience 20101001 |
| Transcriptional regulation of cannabinoid receptor-1 expression in the liver by retinoic acid acting via retinoic acid receptor-gamma. | The Journal of biological chemistry 20100618 |
| HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer). | British journal of cancer 20090210 |
| Apoptosis induced by synthetic retinoic acid CD437 on human melanoma A375 cells involves RIG-I pathway. | Archives of dermatological research 20090101 |
| Drugs targeting the mitochondrial pore act as cytotoxic and cytostatic agents in temozolomide-resistant glioma cells. | Journal of translational medicine 20090101 |
| Adamantyl-substituted retinoid-derived molecules that interact with the orphan nuclear receptor small heterodimer partner: effects of replacing the 1-adamantyl or hydroxyl group on inhibition of cancer cell growth, induction of cancer cell apoptosis, and inhibition of SRC homology 2 domain-containing protein tyrosine phosphatase-2 activity. | Journal of medicinal chemistry 20080925 |
| Atypical retinoids ST1926 and CD437 are S-phase-specific agents causing DNA double-strand breaks: significance for the cytotoxic and antiproliferative activity. | Molecular cancer therapeutics 20080901 |
| [A novel retinoid CD437 induces apoptosis of human epidermoid carcinoma A431 cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080301 |
| GADD45A is a mediator of CD437 induced apoptosis in ovarian carcinoma cells. | Journal of cellular physiology 20070901 |
| An adamantyl-substituted retinoid-derived molecule that inhibits cancer cell growth and angiogenesis by inducing apoptosis and binds to small heterodimer partner nuclear receptor: effects of modifying its carboxylate group on apoptosis, proliferation, and protein-tyrosine phosphatase activity. | Journal of medicinal chemistry 20070531 |
| Targeting Nur77 translocation. | Expert opinion on therapeutic targets 20070101 |
| Heteroarotinoids with anti-cancer activity against ovarian cancer cells. | The open medicinal chemistry journal 20070101 |
| Comparing the effect of ATRA, 4-HPR, and CD437 in bladder cancer cells. | Frontiers in bioscience : a journal and virtual library 20060901 |
| Antitumor activity of the retinoid-related molecules (E)-3-(4'-hydroxy-3'-adamantylbiphenyl-4-yl)acrylic acid (ST1926) and 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalene carboxylic acid (CD437) in F9 teratocarcinoma: Role of retinoic acid receptor gamma and retinoid-independent pathways. | Molecular pharmacology 20060901 |
| Regulation of Nur77 nuclear export by c-Jun N-terminal kinase and Akt. | Oncogene 20060518 |
| Induction of GDF-15/NAG-1/MIC-1 in human lung carcinoma cells by retinoid-related molecules and assessment of its role in apoptosis. | Cancer biology & therapy 20060501 |
| Synthesis and structure-activity relationships of a new series of retinoid-related biphenyl-4-ylacrylic acids endowed with antiproliferative and proapoptotic activity. | Journal of medicinal chemistry 20050728 |
| Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells. | Cancer research 20050715 |
| Activation of Nur77 by selected 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes induces apoptosis through nuclear pathways. | The Journal of biological chemistry 20050701 |
| Development of resistance to the atypical retinoid, ST1926, in the lung carcinoma cell line H460 is associated with reduced formation of DNA strand breaks and a defective DNA damage response. | Neoplasia (New York, N.Y.) 20050701 |
| Identification of protein modulation by the synthetic retinoid CD437 in lung carcinoma cells using high throughput immunoblotting. | International journal of oncology 20050201 |
| Irradiation specifically sensitises solid tumour cell lines to TRAIL mediated apoptosis. | BMC cancer 20050101 |
| Antagonist analogue of 6-[3'-(1-adamantyl)-4'-hydroxyphenyl]-2-naphthalenecarboxylic acid (AHPN) family of apoptosis inducers that effectively blocks AHPN-induced apoptosis but not cell-cycle arrest. | Journal of medicinal chemistry 20040701 |
| Synthetic retinoids as inducers of apoptosis in ovarian carcinoma cell lines. | Journal of cellular physiology 20040601 |
| A retinoid-related molecule that does not bind to classical retinoid receptors potently induces apoptosis in human prostate cancer cells through rapid caspase activation. | Cancer research 20040501 |
| Identification of retinoid-modulated proteins in squamous carcinoma cells using high-throughput immunoblotting. | Cancer research 20040401 |
| Retinoids induce Fas(CD95) ligand cell surface expression via RARgamma and nur77 in T cells. | European journal of immunology 20040301 |
| Promyelocytic leukemia retinoid signaling targets regulate apoptosis,tissue factor and thrombomodulin expression. | Haematologica 20040301 |
| ST1926, a novel and orally active retinoid-related molecule inducing apoptosis in myeloid leukemia cells: modulation of intracellular calcium homeostasis. | Blood 20040101 |
| Induction of apoptosis in retinoid-refractory acute myelogenous leukemia by a novel AHPN analog. | Blood 20031115 |
| Identification and characterization of a cell cycle and apoptosis regulatory protein-1 as a novel mediator of apoptosis signaling by retinoid CD437. | The Journal of biological chemistry 20030829 |
| Comparison of the mechanism of induction of apoptosis in ovarian carcinoma cells by the conformationally restricted synthetic retinoids CD437 and 4-HPR. | Journal of cellular biochemistry 20030515 |
| A novel atypical retinoid endowed with proapoptotic and antitumor activity. | Journal of medicinal chemistry 20030313 |
| Differential regulation of nonsteroidal anti-inflammatory drug-activated gene in normal human tracheobronchial epithelial and lung carcinoma cells by retinoids. | Molecular pharmacology 20030301 |
| The novel retinoid AHPN/CD437 induces a rapid but incomplete apoptotic response in human myeloma cells. | Biochimica et biophysica acta 20030217 |
| Arginine of retinoic acid receptor beta which coordinates with the carboxyl group of retinoic acid functions independent of the amino acid residues responsible for retinoic acid receptor subtype ligand specificity. | Archives of biochemistry and biophysics 20030115 |
| The apoptotic action of the retinoid CD437/AHPN: diverse effects, common basis. | Journal of biomedical science 20030101 |
| Receptor-independent induction of apoptosis by synthetic retinoids. | Journal of biological regulators and homeostatic agents 20030101 |
| Elucidation of molecular events mediating induction of apoptosis by synthetic retinoids using a CD437-resistant ovarian carcinoma cell line. | The Journal of biological chemistry 20021122 |
| Induction of apoptosis of human B-CLL and ALL cells by a novel retinoid and its nonretinoidal analog. | Blood 20021015 |
| Cyclin B and E2F-1 expression in prostate carcinoma cells treated with the novel retinoid CD437 are regulated by the ubiquitin-mediated pathway. | Cancer research 20020701 |
| Vitamin A and apoptosis in prostate cancer. | Endocrine-related cancer 20020601 |
| The synthetic retinoid CD437 selectively induces apoptosis in human lung cancer cells while sparing normal human lung epithelial cells. | Cancer research 20020415 |
| Correspondence re: A. Kumar et al., cross-resistance to the synthetic retinoid CD437 in a paclitaxel-resistant human ovarian carcinoma cell line is independent of the overexpression of retinoic acid receptor-gamma. Cancer Res., 61: 7552-7555, 2001. | Cancer research 20020401 |
| Classical and novel retinoids: their targets in cancer therapy. | Leukemia 20020401 |
| [Are mitochondria targets of anticancer drugs responsible for apoptosis?]. | Annales de biologie clinique 20020101 |
| Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437. | Oncogene 20011115 |
| Cross-resistance to the synthetic retinoid CD437 in a paclitaxel-resistant human ovarian carcinoma cell line is independent of the overexpression of retinoic acid receptor-gamma. | Cancer research 20011015 |
| Evidence supporting a role for mitochondrial respiration in apoptosis induction by the synthetic retinoid CD437. | Cancer research 20010915 |
| Retinoic acid receptor-independent mechanism of apoptosis of melanoma cells by the retinoid CD437 (AHPN). | Cell death and differentiation 20010901 |
| Apoptosis induction in cancer cells by a novel analogue of 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic acid lacking retinoid receptor transcriptional activation activity. | Cancer research 20010615 |
| Evidence of a lysosomal pathway for apoptosis induced by the synthetic retinoid CD437 in human leukemia HL-60 cells. | Cell death and differentiation 20010501 |
| Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2. | Cell death and differentiation 20010401 |
| Effects of a novel synthetic retinoid on malignant glioma in vitro: inhibition of cell proliferation, induction of apoptosis and differentiation. | European journal of cancer (Oxford, England : 1990) 20010301 |
| Synergistic teratogenic effects induced by retinoids in mice by coadministration of a RARalpha- or RARgamma-selective agonist with a RXR-selective agonist. | Toxicology and applied pharmacology 20010101 |
| Synthetic retinoid CD437 promotes rapid apoptosis in malignant human epidermal keratinocytes and G1 arrest in their normal counterparts. | Journal of cellular physiology 20010101 |
| Induction of the cytochrome P450 gene CYP26 during mucous cell differentiation of normal human tracheobronchial epithelial cells. | Molecular pharmacology 20000901 |
| S-phase arrest and apoptosis induced in normal mammary epithelial cells by a novel retinoid. | Cancer research 20000401 |
| In acute promyelocytic leukemia NB4 cells, the synthetic retinoid CD437 induces contemporaneously apoptosis, a caspase-3-mediated degradation of PML/RARalpha protein and the PML retargeting on PML-nuclear bodies. | Leukemia 19990501 |
| Evidence for the involvement of both retinoic acid receptor- and retinoic X receptor-dependent signaling pathways in the induction of tissue transglutaminase and apoptosis in the human myeloma cell line RPMI 8226. | Blood 19980401 |
| Retinoid-induced apoptosis and Sp1 cleavage occur independently of transcription and require caspase activation. | Molecular and cellular biology 19971101 |
| Induction of apoptosis by retinoids and retinoic acid receptor gamma-selective compounds in mouse thymocytes through a novel apoptosis pathway. | Molecular pharmacology 19970601 |
| Synthesis, structure-affinity relationships, and biological activities of ligands binding to retinoic acid receptor subtypes. | Journal of medicinal chemistry 19951222 |