Home Aminos 3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate

3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate

CAS No.:
123441-03-2
Catalog Number:
AG000KLF
Molecular Formula:
C14H22N2O2
Molecular Weight:
250.3367
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$63
- +
5g
98%
In Stock USA
United States
$213
- +
10g
98%
In Stock USA
United States
$350
- +
25g
98%
In Stock USA
United States
$532
- +
Product Description
Catalog Number:
AG000KLF
Chemical Name:
3-[(1S)-1-(dimethylamino)ethyl]phenyl N-ethyl-N-methylcarbamate
CAS Number:
123441-03-2
Molecular Formula:
C14H22N2O2
Molecular Weight:
250.3367
MDL Number:
MFCD00871496
IUPAC Name:
[3-[(1S)-1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
InChI:
InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3/t11-/m0/s1
InChI Key:
XSVMFMHYUFZWBK-NSHDSACASA-N
SMILES:
CCN(C(=O)Oc1cccc(c1)[C@@H](N(C)C)C)C
EC Number:
602-936-0
UNII:
PKI06M3IW0
Properties
Complexity:
269  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
250.168g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
250.342g/mol
Monoisotopic Mass:
250.168g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
32.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.3  
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[Progressive supranucleair palsy: acetylcholineeserase-inhibitor a possible therapy?]. Tijdschrift voor gerontologie en geriatrie 20090601
Treatment of Alzheimer's disease in the long-term-care setting. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090515
Rivastigmine for the prevention of postoperative delirium in elderly patients undergoing elective cardiac surgery--a randomized controlled trial. Critical care medicine 20090501
Cholinergic modulation of MEG resting-state oscillatory activity in Parkinson's disease related dementia. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20090501
Pharmacokinetics of a novel transdermal rivastigmine patch for the treatment of Alzheimer's disease: a review. International journal of clinical practice 20090501
[Frontotemporal dementia: neurotransmitter and clinical symptoms with focus on therapeutic targets]. Fortschritte der Neurologie-Psychiatrie 20090501
Rivastigmine reduces tobacco craving in alcohol-dependent smokers. Pharmacopsychiatry 20090501
Rivastigmine for Alzheimer's disease. The Cochrane database of systematic reviews 20090415
Similar rivastigmine pharmacokinetics and pharmacodynamics in Japanese and white healthy participants following the application of novel rivastigmine patch. Journal of clinical pharmacology 20090401
Cholinesterase inhibitors and beyond. Current Alzheimer research 20090401
[Treatment of degenerative dementia disorders--who should be treated?]. Ugeskrift for laeger 20090302
Long-term rivastigmine treatment in a routine clinical setting. Acta neurologica Scandinavica 20090301
Acteylcholinesterase inhibitor rivastigmine enhances cellular defenses in neuronal and macrophage-like cell lines. Translational research : the journal of laboratory and clinical medicine 20090301
Side effects of approved antidementives. Psychiatria Danubina 20090301
Effects of cholinesterase inhibition on brain white matter volume in Alzheimer's disease. Neuroreport 20090218
BuChE-K and APOE epsilon4 allele frequencies in Lewy body dementias, and influence of genotype and hyperhomocysteinemia on cognitive decline. Movement disorders : official journal of the Movement Disorder Society 20090215
Top cited papers in International Psychogeriatrics: 1. Long-term use of rivastigmine in patients with dementia with Lewy bodies: an open-label trial. International psychogeriatrics 20090201
Simultaneous determination of galantamine, rivastigmine and NAP 226-90 in plasma by MEKC and its application in Alzheimer's disease. Electrophoresis 20090201
Long-term effects of rivastigmine capsules in patients with traumatic brain injury. Brain injury 20090201
Different cholinesterase inhibitor effects on CSF cholinesterases in Alzheimer patients. Current Alzheimer research 20090201
Adherence to cholinesterase inhibitors in patients with Alzheimer's disease. Journal of the American Geriatrics Society 20090201
Rivastigmine patches: line extension. No therapeutic advantage and less convenient than capsules. Prescrire international 20090201
Rivastigmine for dementia in people with Down syndrome. The Cochrane database of systematic reviews 20090121
Design, synthesis and AChE inhibitory activity of indanone and aurone derivatives. European journal of medicinal chemistry 20090101
Accommodation of physostigmine and its analogues by acetylcholinesterase is dominated by hydrophobic interactions. The Biochemical journal 20090101
Methylthioninium chloride reverses cognitive deficits induced by scopolamine: comparison with rivastigmine. Psychopharmacology 20090101
Multifunctional neuroprotective derivatives of rasagiline as anti-Alzheimer's disease drugs. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20090101
Cognitive impairment and preferences for current health. Health and quality of life outcomes 20090101
Improvement of spontaneous speech in early stage Alzheimer's with rivastigmine. The journal of nutrition, health & aging 20090101
[The role of rivastigmine (exelon) in the treatment of consequences of cranial-brain trauma]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
Pharmacological interventions in primary care: hopes and illusions. Frontiers of neurology and neuroscience 20090101
Is it possible to treat vascular dementia? Frontiers of neurology and neuroscience 20090101
Dementia with Lewy bodies: clinical diagnosis and therapeutic approach. Frontiers of neurology and neuroscience 20090101
Changes in cognitive domains during three years in patients with Alzheimer's disease treated with donepezil. BMC neurology 20090101
[Transdermal rivastigmine patch in outpatient services in Austria: a naturalistic study in 103 patients with Alzheimer dementia]. Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater 20090101
Inhibitory potency of choline esterase inhibitors on acetylcholine release and choline esterase activity in fresh specimens of human and rat neocortex. Journal of Alzheimer's disease : JAD 20090101
Switching from donepezil tablets to rivastigmine transdermal patch in Alzheimer's disease. American journal of Alzheimer's disease and other dementias 20090101
Novel regimens and delivery systems in the pharmacological treatment of Alzheimer's disease. CNS drugs 20090101
Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately? The open neurology journal 20090101
Effects of rivastigmine and donepezil on brain acetylcholine levels in acetylcholinesterase-deficient mice. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20090101
Safety and tolerability of the rivastigmine patch: results of a 28-week open-label extension. Alzheimer disease and associated disorders 20090101
Dementia care initiative in primary practice: study protocol of a cluster randomized trial on dementia management in a general practice setting. BMC health services research 20090101
Persistence with cholinesterase inhibitor therapy for dementia: an observational administrative health database study. Drugs & aging 20090101
Update on the use of memantine in Alzheimer's disease. Neuropsychiatric disease and treatment 20090101
DOMINO-AD protocol: donepezil and memantine in moderate to severe Alzheimer's disease - a multicentre RCT. Trials 20090101
[Results of the open multicenter prospective study of safety and tolerability of rivastigmine (exelon) in different titration regimes in mild and moderate Alzheimer's disease]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20090101
Can cognitive enhancers reduce the risk of falls in older people with mild cognitive impairment? A protocol for a randomised controlled double blind trial. BMC neurology 20090101
Functional neural network analysis in frontotemporal dementia and Alzheimer's disease using EEG and graph theory. BMC neuroscience 20090101
Quality of life as an outcome in Alzheimer's disease and other dementias--obstacles and goals. BMC neurology 20090101
Current treatments of Alzheimer disease: are main caregivers satisfied with the drug treatments received by their patients? Dementia and geriatric cognitive disorders 20090101
The prevention and treatment of cognitive decline and dementia: An overview of recent research on experimental treatments. Indian journal of psychiatry 20090101
Neurometabolic correlations of donepezil and rivastigmine in dementia patients: a different neuroprotective effect. The Journal of neuropsychiatry and clinical neurosciences 20090101
Safety/Tolerability and efficacy of rivastigmine in taiwanese patients with Alzheimer's disease: a prospective post-marketing surveillance study. Clinical drug investigation 20090101
Persistent treatment with cholinesterase inhibitors and/or memantine slows clinical progression of Alzheimer disease. Alzheimer's research & therapy 20090101
Safety and tolerability of donepezil, rivastigmine and galantamine for patients with Alzheimer's disease: systematic review of the 'real-world' evidence. Dementia and geriatric cognitive disorders 20090101
Have last-observation-carried-forward analyses caused us to favour more toxic dementia therapies over less toxic alternatives? A systematic review. Open medicine : a peer-reviewed, independent, open-access journal 20090101
Gender differences in the pharmacokinetics of rivastigmine in rats. Arzneimittel-Forschung 20090101
Support for a tax increase to provide unrestricted access to an Alzheimer's disease medication: a survey of the general public in Canada. BMC health services research 20090101
Clinical practice with antidementia and antipsychotic drugs: Audit from a geriatric clinic in India. Indian journal of psychiatry 20090101
Predictors of long-term treatment effect of rivastigmine in Alzheimer's disease: a role for beta-amyloid plasma levels? Neurologia i neurochirurgia polska 20090101
Development and validation of a spectrofluorimetric method for the estimation of rivastigmine in formulations. Indian journal of pharmaceutical sciences 20090101
Treatment disparities in medication prescribing for Alzheimer's: disease among ethnic groups. Journal of health care finance 20090101
Mild cognitive impairment: The dilemma. Indian journal of psychiatry 20090101
Vascular cognitive impairment. Indian journal of psychiatry 20090101
Frontotemporal dementia: An updated overview. Indian journal of psychiatry 20090101
Memory clinics in context. Indian journal of psychiatry 20090101
Behavioral and psychological symptoms of dementia and their management. Indian journal of psychiatry 20090101
Safety and efficacy of antipsychotic drugs for the behavioral and psychological symptoms of dementia. Indian journal of psychiatry 20090101
Screening the methanol extracts of some Iranian plants for acetylcholinesterase inhibitory activity. Research in pharmaceutical sciences 20090101
Use of rivastigmine transdermal patch in the treatment of Alzheimer's disease. Expert opinion on drug delivery 20081201
Acetylcholinesterase-inhibiting activity of pyrrole derivatives from a novel marine gliding bacterium, Rapidithrix thailandica. Marine drugs 20081201
Impact of cholinesterase inhibitors on behavioral and psychological symptoms of Alzheimer's disease: a meta-analysis. Clinical interventions in aging 20081201
Pharmacology and therapeutic potential of sigma(1) receptor ligands. Current neuropharmacology 20081201
Brain cholinergic impairment in liver failure. Brain : a journal of neurology 20081101
Darifenacin treatment for overactive bladder in patients who expressed dissatisfaction with prior extended-release antimuscarinic therapy. International journal of clinical practice 20081101
Relative tolerability of Alzheimer's disease treatments. Psychiatry (Edgmont (Pa. : Township)) 20081101
Suppression of neuroinflammation and immunomodulation by the acetylcholinesterase inhibitor rivastigmine. Journal of neuroimmunology 20081015
Effects of cholinesterase inhibitors on rat nicotinic receptor levels in vivo and in vitro. Journal of neural transmission (Vienna, Austria : 1996) 20081001
Pharmacological treatment in moderate-to-severe Alzheimer's disease. Expert opinion on pharmacotherapy 20081001
Diagnosis and management of Parkinson's disease dementia. International journal of clinical practice 20081001
The efficacy of mirtazapine in agitated patients with Alzheimer's disease: A 12-week open-label pilot study. Neuropsychiatric disease and treatment 20081001
Errorless learning and spaced retrieval techniques to relearn instrumental activities of daily living in mild Alzheimer's disease: A case report study. Neuropsychiatric disease and treatment 20081001
Neuropharmacology. Indian journal of pharmacology 20081001
Study of neuroprotection of donepezil, a therapy for Alzheimer's disease. Chemico-biological interactions 20080925
The neuroprotective effect of ladostigil against hydrogen peroxide-mediated cytotoxicity. Chemico-biological interactions 20080925
[Neuropsychiatric and cognitive symptoms in Parkinson disease]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080925
Evaluation of the cardiovascular and subjective effects of rivastigmine in combination with methamphetamine in methamphetamine-dependent human volunteers. The international journal of neuropsychopharmacology 20080901
Safety, efficacy, and biomarker findings of PBT2 in targeting Abeta as a modifying therapy for Alzheimer's disease: a phase IIa, double-blind, randomised, placebo-controlled trial. The Lancet. Neurology 20080901
Efficacy, safety and tolerability of rivastigmine capsules in patients with probable vascular dementia: the VantagE study. Current medical research and opinion 20080901
[Alzheimer type dementia]. Revue de l'infirmiere 20080901
Effects of rivastigmine on memory and cognition in multiple sclerosis. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20080901
Drug utilization review of cholinesterase inhibitors in Quebec. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20080901
[A transdermal patch of rivastigmine (Exelon)]. Revue medicale de Liege 20080901
A study of rivastigmine liposomes for delivery into the brain through intranasal route. Acta pharmaceutica (Zagreb, Croatia) 20080901
Role of the central cholinergic system in the therapeutics of schizophrenia. Current neuropharmacology 20080901
Rivastigmine versus placebo in hyperhomocysteinemic Parkinson's disease dementia patients. Movement disorders : official journal of the Movement Disorder Society 20080815
Rivastigmine in Parkinson's disease dementia. Expert review of neurotherapeutics 20080801
Delayed-onset hepatic encephalopathy induced by zolpidem: a case report. Clinics (Sao Paulo, Brazil) 20080801
Rivastigmine transdermal patch: role in the management of Alzheimer's disease. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20080801
The effects of rivastigmine plus selegiline on brain acetylcholinesterase, (Na, K)-, Mg-ATPase activities, antioxidant status, and learning performance of aged rats. Neuropsychiatric disease and treatment 20080801
Current approaches to the treatment of Parkinson's disease. Neuropsychiatric disease and treatment 20080801
Present and prospective clinical therapeutic regimens for Alzheimer's disease. Neuropsychiatric disease and treatment 20080801
Psychiatric disorders and traumatic brain injury. Neuropsychiatric disease and treatment 20080801
Prevalence of cholinesterase inhibitors in subjects with dementia in Europe. Pharmacoepidemiology and drug safety 20080701
Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20080701
Exploiting protein fluctuations at the active-site gorge of human cholinesterases: further optimization of the design strategy to develop extremely potent inhibitors. Journal of medicinal chemistry 20080612
Rivastigmine effects on EEG spectra and three-dimensional LORETA functional imaging in Alzheimer's disease. Psychopharmacology 20080601
Complete atrioventricular block associated with rivastigmine therapy. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20080601
Miniaturized membrane sensors for the determination of rivastigmine hydrogen tartrate. Chemical & pharmaceutical bulletin 20080601
Growth hormone and insulin-like growth factor-I as an endocrine axis in Alzheimer's disease. Endocrine, metabolic & immune disorders drug targets 20080601
Comparison of cholinesterase inhibitor utilization patterns and associated health care costs in Alzheimer's disease. Journal of managed care pharmacy : JMCP 20080601
Strategies for molecular imaging dementia and neurodegenerative diseases. Neuropsychiatric disease and treatment 20080601
Antipsychotics for the treatment of behavioral and psychological symptoms of dementia (BPSD). Current neuropharmacology 20080601
Benzofuran-based hybrid compounds for the inhibition of cholinesterase activity, beta amyloid aggregation, and abeta neurotoxicity. Journal of medicinal chemistry 20080522
[A comparative study of the effectiveness and tolerability of a procedure involving slow dose-escalation of rivastigmine in patients with mild or moderate Alzheimer-type dementia: the SCALEX study]. Revista de neurologia 20080501
Dementia medications in palliative care #174. Journal of palliative medicine 20080501
[Treatment of Alzheimer's disease: status quo and future considerations]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080501
Parkinson's disease in the elderly. Medicine and health, Rhode Island 20080501
Diagnosis and treatment of dementia with Lewy bodies. JAAPA : official journal of the American Academy of Physician Assistants 20080501
AAFP and ACP release guideline on dementia treatment. American family physician 20080415
Bis-(-)-nor-meptazinols as novel nanomolar cholinesterase inhibitors with high inhibitory potency on amyloid-beta aggregation. Journal of medicinal chemistry 20080410
In situ-forming oleogel implant for rivastigmine delivery. Pharmaceutical research 20080401
Facile synthesis of new carbon-11 labeled conformationally restricted rivastigmine analogues as potential PET agents for imaging AChE and BChE enzymes. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20080401
The acetylcholinesterase inhibitor rivastigmine does not alter total choices for methamphetamine, but may reduce positive subjective effects, in a laboratory model of intravenous self-administration in human volunteers. Pharmacology, biochemistry, and behavior 20080401
Acute neuropsychological effects of MDMA and ethanol (co-)administration in healthy volunteers. Psychopharmacology 20080401
Synergistic effect of apolipoprotein E epsilon4 and butyrylcholinesterase K-variant on progression from mild cognitive impairment to Alzheimer's disease. Pharmacogenetics and genomics 20080401
A randomised, blinded, placebo-controlled trial in dementia patients continuing or stopping neuroleptics (the DART-AD trial). PLoS medicine 20080401
[Treatment pattern of Alzheimer's disease with cholinesterase inhibitors (TRAIN study)]. Revista de neurologia 20080401
Prolonged cholinergic enrichment influences regional cortical activation in early Alzheimer's disease. Neuropsychiatric disease and treatment 20080401
A rivastigmine patch for dementia. The Medical letter on drugs and therapeutics 20080324
Poly(n-butylcyanoacrylate) nanoparticles coated with polysorbate 80 for the targeted delivery of rivastigmine into the brain to treat Alzheimer's disease. Brain research 20080320
A nanoparticulate drug-delivery system for rivastigmine: physico-chemical and in vitro biological characterization. Macromolecular bioscience 20080310
Summaries for patients. Drug treatment for patients with dementia: American College of Physicians and American Academy of Family Physicians recommendations. Annals of internal medicine 20080304
Current pharmacologic treatment of dementia: a clinical practice guideline from the American College of Physicians and the American Academy of Family Physicians. Annals of internal medicine 20080304
Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline. Annals of internal medicine 20080304
No significant effects of single intravenous, single oral and subchronic oral administration of acetylcholinesterase inhibitors on striatal [123I]FP-CIT binding in rats. European journal of nuclear medicine and molecular imaging 20080301
[Antidementia drugs--response or non-response?]. Der Internist 20080301
How long can patients with mild or moderate Alzheimer's dementia maintain both the cognition and the therapy of cholinesterase inhibitors: a national population-based study. European journal of neurology 20080301
Olanzapine-associated neuroleptic malignant syndrome in a patient receiving concomitant rivastigmine therapy. Pharmacotherapy 20080301
Pharmacodynamics of memantine: an update. Current neuropharmacology 20080301
Microcalorimetric study of the inhibition of butyrylcholinesterase by carbamates. Analytical biochemistry 20080215
Omega-3 supplementation in mild to moderate Alzheimer's disease: effects on neuropsychiatric symptoms. International journal of geriatric psychiatry 20080201
A randomised double-blind placebo-controlled trial of folic acid supplementation of cholinesterase inhibitors in Alzheimer's disease. International journal of geriatric psychiatry 20080201
Acetylcholinesterase inhibitors in assisted living: patterns of use and association with retention. International journal of geriatric psychiatry 20080201
Armodafinil improves wakefulness and long-term episodic memory in nCPAP-adherent patients with excessive sleepiness associated with obstructive sleep apnea. Sleep & breathing = Schlaf & Atmung 20080201
Neurological signs in relation to type of cerebrovascular disease in vascular dementia. Stroke 20080201
Prolonged QT interval, syncope, and delirium with galantamine. The Annals of pharmacotherapy 20080201
Pharmacokinetics and bioavailability of the novel rivastigmine transdermal patch versus rivastigmine oral solution in healthy elderly subjects. Journal of clinical pharmacology 20080201
Memantine treatment in patients with mild to moderate Alzheimer's disease already receiving a cholinesterase inhibitor: a randomized, double-blind, placebo-controlled trial. Current Alzheimer research 20080201
Pharmacologic management of Alzheimer disease. The Journal of neuroscience nursing : journal of the American Association of Neuroscience Nurses 20080201
[Cholinesterase inhibitors in the treatment of dementia--are they useful in clinical practice?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20080131
Cholinesterase inhibitors for delirium. The Cochrane database of systematic reviews 20080123
alpha,beta-Dehydrophenylalanine choline esters, a new class of reversible inhibitors of human acetylcholinesterase and butyrylcholinesterase. Chemico-biological interactions 20080110
Pharmacokinetics and pharmacodynamics of the novel daily rivastigmine transdermal patch compared with twice-daily capsules in Alzheimer's disease patients. Clinical pharmacology and therapeutics 20080101
The role of the cerebellum in schizophrenia: an update of clinical, cognitive, and functional evidences. Schizophrenia bulletin 20080101
[Therapy of cognitive deficits in schizophrenia with acetylcholinesterase inhibitors. A systematic overview]. Der Nervenarzt 20080101
Rivastigmine in Wernicke-Korsakoff's syndrome: five patients with rivastigmine showed no more improvement than five patients without rivastigmine. Alcohol and alcoholism (Oxford, Oxfordshire) 20080101
Identification of responders to rivastigmine: a prospective cohort study. Dementia and geriatric cognitive disorders 20080101
A systematic review of the effectiveness of rivastigmine for the treatment of behavioral disturbances in dementia and other neurological disorders. Current medical research and opinion 20080101
Education and use of dementia drugs: a register-based study of over 600,000 older people. Dementia and geriatric cognitive disorders 20080101
Effects of rivastigmine on tremor and other motor symptoms in patients with Parkinson's disease dementia: a retrospective analysis of a double-blind trial and an open-label extension. Drug safety 20080101
Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration. Journal of neuroinflammation 20080101
Different responses to rivastigmine in subcortical vascular dementia and multi-infarct dementia. American journal of Alzheimer's disease and other dementias 20080101
Pharmacogenomics in Alzheimer's disease. Methods in molecular biology (Clifton, N.J.) 20080101
[Treatment of Alzheimer's Disease cognitive symptoms]. Vertex (Buenos Aires, Argentina) 20080101
Estimated pre-morbid IQ effects on cognitive and functional outcomes in Alzheimer disease: a longitudinal study in a treated cohort. BMC psychiatry 20080101
Steady-state pharmacokinetics of rivastigmine in patients with mild to moderate Alzheimer's disease not affected by co-administration of memantine: an open-label, crossover, single-centre study. Clinical drug investigation 20080101
Healthcare costs and utilization for Medicare beneficiaries with Alzheimer's. BMC health services research 20080101
Variability in the diagnosis and management of patients with Alzheimer's disease and cerebrovascular disease: results from the GALATEA multicentre, observational study. Clinical drug investigation 20080101
A randomized controlled trial of a novel mixed monoamine reuptake inhibitor in adults with ADHD. Behavioral and brain functions : BBF 20080101
Impact of rivastigmine on caregiver burden associated with Alzheimer's disease in both informal care and nursing home settings. Drugs & aging 20080101
Fluorimetric determination of rivastigmine in rat plasma by a reverse phase--high performance liquid chromatographic method. Application to a pharmacokinetic study. Arzneimittel-Forschung 20080101
Pathophysiology and treatment of psychosis in Parkinson's disease: a review. Drugs & aging 20080101
Efficacy and safety of donepezil, galantamine, and rivastigmine for the treatment of Alzheimer's disease: a systematic review and meta-analysis. Clinical interventions in aging 20080101
A review of RCTs in four medical journals to assess the use of imputation to overcome missing data in quality of life outcomes. Trials 20080101
Transdermal delivery of treatment for Alzheimer's disease: development, clinical performance and future prospects. Drugs & aging 20080101
Safety and efficacy of rivastigmine in patients with Alzheimer's disease not responding adequately to donepezil: an open-label study. Primary care companion to the Journal of clinical psychiatry 20080101
A pilot study of rivastigmine in the treatment of delirium after stroke: a safe alternative. BMC neurology 20080101
[The treatment of Alzheimer's disease in patients with comorbid somatic pathology]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20080101
The therapeutical potential of alpha-synuclein antiaggregatory agents for dementia with Lewy bodies. Current medicinal chemistry 20080101
Student pharmacists: don't forget the product labeling. Journal of the American Pharmacists Association : JAPhA 20080101
Neurological and psychiatric practitioners' views on Alzheimer's disease and treatment thereof. Dementia and geriatric cognitive disorders 20080101
Intranasal administration of acetylcholinesterase inhibitors. BMC neuroscience 20080101
A new way of data interpretation for cognition tests in rats used to characterise six choline esterase inhibitors with heterocyclic nitrogen bridgehead structure. Application in Alzheimer therapy. Arzneimittel-Forschung 20080101
Long-term safety and tolerability of rivastigmine in patients with Alzheimer's disease switched from donepezil: an open-label extension study. Primary care companion to the Journal of clinical psychiatry 20080101
Discontinuing Alzheimer's disease drug therapy: why, when, and how. Director (Cincinnati, Ohio) 20080101
Cognitive rehabilitation for reversible and progressive brain injury. Indian journal of psychiatry 20080101
Once-daily transdermal rivastigmine in the treatment of Alzheimer's disease. Drug design, development and therapy 20080101
Comparison of persistence rates of acetylcholine-esterase inhibitors in a state Medicaid program. Patient preference and adherence 20080101
Neuroinflammation and tumor necrosis factor signaling in the pathophysiology of Alzheimer's disease. Journal of inflammation research 20080101
Focusing effect of acetylcholine on neuroplasticity in the human motor cortex. The Journal of neuroscience : the official journal of the Society for Neuroscience 20071226
[Pharmacological treatment options in frontotemporal dementia]. Fortschritte der Neurologie-Psychiatrie 20071201
A new lupene triterpenetriol and anticholinesterase activity of Salvia sclareoides. Fitoterapia 20071201
Rivastigmine exposure provided by a transdermal patch versus capsules. Current medical research and opinion 20071201
Rivastigmine-induced dystonia. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20071201
An update on the pharmacology of galantamine. Expert opinion on investigational drugs 20071201
Risperidone, olanzapine and quetiapine in the treatment of behavioral and psychological symptoms in patients with Alzheimer's disease: preliminary findings from a naturalistic, retrospective study. Psychiatry and clinical neurosciences 20071201
Management of the behavioral and psychological symptoms of dementia. Clinical interventions in aging 20071201
The challenge of supporting care for dementia in primary care. Clinical interventions in aging 20071201
Rivastigmine in Alzheimer's disease: Cognitive function and quality of life. Therapeutics and clinical risk management 20071201
A review on primary progressive aphasia. Neuropsychiatric disease and treatment 20071201
Rivastigmine for the treatment of dementia associated with Parkinson's disease. Neuropsychiatric disease and treatment 20071201
Rivastigmine in Chinese patients with subcortical vascular dementia. Neuropsychiatric disease and treatment 20071201
Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions. Current neuropharmacology 20071201
Current therapeutic options for Alzheimer's disease. Current genomics 20071201
[Rivastigmine against dementia in Parkinson disease?]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20071115
A review of compliance to treatment in Alzheimer's disease: potential benefits of a transdermal patch. Current medical research and opinion 20071101
A rivastigmine patch for the treatment of Alzheimer's disease and Parkinson's disease dementia. Expert review of neurotherapeutics 20071101
Cholinesterase inhibitors in mild cognitive impairment: a systematic review of randomised trials. PLoS medicine 20071101
N1phenethyl-norcymserine, a selective butyrylcholinesterase inhibitor, increases acetylcholine release in rat cerebral cortex: a comparison with donepezil and rivastigmine. European journal of pharmacology 20071031
Novel class of quinone-bearing polyamines as multi-target-directed ligands to combat Alzheimer's disease. Journal of medicinal chemistry 20071004
Rivastigmine: a placebo controlled trial of twice daily and three times daily regimens in patients with Alzheimer's disease. Journal of neurology, neurosurgery, and psychiatry 20071001
Subthreshold depression in patients with Parkinson's disease and dementia--clinical and demographic correlates. International journal of geriatric psychiatry 20071001
[Lewy body dementia and Parkinson disease dementia]. Presse medicale (Paris, France : 1983) 20071001
Treatment of dementia in community-dwelling and institutionalized medicare beneficiaries. Journal of the American Geriatrics Society 20071001
Patient and caregiver outcomes after 6 +/- 1.5-months of rivastigmine therapy for mild-to-moderate Alzheimer's disease: the Belgian FExT study. Current medical research and opinion 20071001
Evaluation of centrally acting cholinesterase inhibitor exposures in adults. The Annals of pharmacotherapy 20071001
Does serotonin augmentation have any effect on cognition and activities of daily living in Alzheimer's dementia? A double-blind, placebo-controlled clinical trial. Journal of clinical psychopharmacology 20071001
Cholinesterase inhibitors: tremor and exacerbation of Parkinson's disease. Prescrire international 20071001
Cholinergic balance in dementia with Lewy bodies: reversible worsening of Parkinsonism at rivastigmine dosage modulation. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20071001
Pharmacotherapy of Alzheimer disease. Canadian journal of psychiatry. Revue canadienne de psychiatrie 20071001
[Cardiovascular effects of cholinesterase inhibitors in Alzheimer's disease]. Revue neurologique 20071001
Diagnosis and management of vascular cognitive impairment. Current atherosclerosis reports 20071001
Progress update: Pharmacological treatment of Alzheimer's disease. Neuropsychiatric disease and treatment 20071001
Potential cognitive enhancing and disease modification effects of SSRIs for Alzheimer's disease. Neuropsychiatric disease and treatment 20071001
[Are anti-dementia drugs worthwhile?]. MMW Fortschritte der Medizin 20070913
Cholinesterase inhibitors in dementia with Lewy bodies: a comparative analysis. International journal of geriatric psychiatry 20070901
Motor-skill learning in Alzheimer's disease: a review with an eye to the clinical practice. Neuropsychology review 20070901
Efficacy and adverse effects of cholinesterase inhibitors and memantine in vascular dementia: a meta-analysis of randomised controlled trials. The Lancet. Neurology 20070901
Anti-dementia drugs and hippocampal-dependent memory in rodents. Behavioural pharmacology 20070901
NICE judgement leaves behind a nasty taste. Nursing older people 20070901
Vascular dementia: pharmacological treatment approaches and perspectives. Clinical interventions in aging 20070901
Pharmacokinetic rationale for the rivastigmine patch. Neurology 20070724
IDEAL: a 6-month, double-blind, placebo-controlled study of the first skin patch for Alzheimer disease. Neurology 20070724
Caregiver preference for rivastigmine patches versus capsules for the treatment of Alzheimer disease. Neurology 20070724
Rationale for transdermal drug administration in Alzheimer disease. Neurology 20070724
Impairment of nonverbal recognition in Alzheimer disease: a PET O-15 study. Neurology 20070703
Executive dyscontrol in dementia, with emphasis on subcortical pathology and the role of butyrylcholinesterase. Current Alzheimer research 20070701
Rivastigmine in dementia associated with Parkinson's disease and Alzheimer's disease: similarities and differences. Journal of Alzheimer's disease : JAD 20070701
Molecular pathology and pharmacogenomics in Alzheimer's disease: polygenic-related effects of multifactorial treatments on cognition, anxiety and depression. Methods and findings in experimental and clinical pharmacology 20070701
A rapid and sensitive liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for the estimation of rivastigmine in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601
The kinetics of inhibition of human acetylcholinesterase and butyrylcholinesterase by two series of novel carbamates. Molecular pharmacology 20070601
Potential ethnic modifiers in the assessment and treatment of Alzheimer's disease: challenges for the future. International psychogeriatrics 20070601
Memory enhancing drugs and Alzheimer's disease: enhancing the self or preventing the loss of it? Medicine, health care, and philosophy 20070601
EXACT: rivastigmine improves the high prevalence of attention deficits and mood and behaviour symptoms in Alzheimer's disease. International journal of clinical practice 20070601
MCI treatment trials: failure or not? The Lancet. Neurology 20070601
Effect of rivastigmine on delay to diagnosis of Alzheimer's disease from mild cognitive impairment: the InDDEx study. The Lancet. Neurology 20070601
[Cholinesterase inhibitors and Alzheimer's disease: meta-analysis of the verification of effectiveness, origin and bias of results in published studies]. Deutsche medizinische Wochenschrift (1946) 20070601
[Rivastigmine solution prescribing habits in patients with Alzheimer-type dementia in Spain (RIVASOL study)]. Revista de neurologia 20070601
Rivastigmine tartrate with a focus on dementia associated with Parkinson's disease. Drugs of today (Barcelona, Spain : 1998) 20070601
Atypical antipsychotics for the treatment of dementia-related behaviors: an update. Medicine and health, Rhode Island 20070601
Treating senile dementia with traditional Chinese medicine. Clinical interventions in aging 20070601
The role of I-ioflupane SPECT dopamine transporter imaging in the diagnosis and treatment of patients with dementia with Lewy bodies. Neuropsychiatric disease and treatment 20070601
Donepezil in Alzheimer's disease: From conventional trials to pharmacogenetics. Neuropsychiatric disease and treatment 20070601
[Acetylcholinesterase inhibitors for dementia--an update]. MMW Fortschritte der Medizin 20070521
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