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Derazantinib

CAS No.:
1234356-69-4
Catalog Number:
AG000KK9
Molecular Formula:
C29H29FN4O
Molecular Weight:
468.5652
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
2mg
99%
1 week
United States
$373
- +
5mg
99%
1 week
United States
$540
- +
10mg
99%
1 week
United States
$807
- +
25mg
99%
1 week
United States
$1557
- +
50mg
99%
1 week
United States
$2390
- +
100mg
99%
1 week
United States
$4057
- +
Product Description
Catalog Number:
AG000KK9
Chemical Name:
Derazantinib
CAS Number:
1234356-69-4
Molecular Formula:
C29H29FN4O
Molecular Weight:
468.5652
MDL Number:
MFCD30532770
IUPAC Name:
(6R)-6-(2-fluorophenyl)-N-[3-[2-(2-methoxyethylamino)ethyl]phenyl]-5,6-dihydrobenzo[h]quinazolin-2-amine
InChI:
InChI=1S/C29H29FN4O/c1-35-16-15-31-14-13-20-7-6-8-22(17-20)33-29-32-19-21-18-26(24-10-4-5-12-27(24)30)23-9-2-3-11-25(23)28(21)34-29/h2-12,17,19,26,31H,13-16,18H2,1H3,(H,32,33,34)/t26-/m1/s1
InChI Key:
KPJDVVCDVBFRMU-AREMUKBSSA-N
SMILES:
COCCNCCc1cccc(c1)Nc1ncc2c(n1)c1ccccc1[C@@H](C2)c1ccccc1F
UNII:
N9B0H171MJ
Properties
Complexity:
638  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
468.233g/mol
Formal Charge:
0
Heavy Atom Count:
35  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
468.576g/mol
Monoisotopic Mass:
468.233g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
59.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.3  
Literature
Title Journal
A Phase 1 study of ARQ 087, an oral pan-FGFR inhibitor in patients with advanced solid tumours. British journal of cancer 20171121
Preclinical Activity of ARQ 087, a Novel Inhibitor Targeting FGFR Dysregulation. PloS one 20160101
Properties