Home Other Building Blocks 5-Formyluracil

5-Formyluracil

CAS No.:
1195-08-0
Catalog Number:
AG000IVX
Molecular Formula:
C5H4N2O3
Molecular Weight:
140.0969
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
98%
In Stock USA
United States
$63
- +
1g
98%
In Stock USA
United States
$144
- +
5g
98%
In Stock USA
United States
$525
- +
10g
98%
In Stock USA
United States
$919
- +
Product Description
Catalog Number:
AG000IVX
Chemical Name:
5-Formyluracil
CAS Number:
1195-08-0
Molecular Formula:
C5H4N2O3
Molecular Weight:
140.0969
MDL Number:
MFCD00192185
IUPAC Name:
2,4-dioxo-1H-pyrimidine-5-carbaldehyde
InChI:
InChI=1S/C5H4N2O3/c8-2-3-1-6-5(10)7-4(3)9/h1-2H,(H2,6,7,9,10)
InChI Key:
OHAMXGZMZZWRCA-UHFFFAOYSA-N
SMILES:
O=Cc1c[nH]c(=O)[nH]c1=O
UNII:
F2SUM4W8EB
Properties
Complexity:
231  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
140.022g/mol
Formal Charge:
0
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
140.098g/mol
Monoisotopic Mass:
140.022g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
75.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1  
Literature
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DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the hNEIL1 and hNTH1 enzymes in human cells. DNA repair 20050102
Schiff base-mediated base pairing. Nucleic acids symposium series (2004) 20050101
5-Formyluracil-induced perturbations of DNA function. Biochemistry 20040518
Qualitative and quantitative analyses of the decomposition products that arise from the exposure of thymine to monochromatic ultrasoft X rays and 60Co gamma rays in the solid state. Radiation research 20040401
Nucleotide excision repair of 5-formyluracil in vitro is enhanced by the presence of mismatched bases. Biochemistry 20040316
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Mammalian 5-formyluracil-DNA glycosylase. 2. Role of SMUG1 uracil-DNA glycosylase in repair of 5-formyluracil and other oxidized and deaminated base lesions. Biochemistry 20030506
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Mutations induced by 5-formyl-2'-deoxyuridine in Escherichia coli include base substitutions that can arise from mispairs of 5-formyluracil with guanine, cytosine and thymine. Mutation research 20010509
Role of the Escherichia coli and human DNA glycosylases that remove 5-formyluracil from DNA in the prevention of mutations. Journal of radiation research 20010301
5-Formyluracil and its nucleoside derivatives confer toxicity and mutagenicity to mammalian cells by interfering with normal RNA and DNA metabolism. Toxicology letters 20010203
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Properties