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Avibactam sodium

CAS No.:
1192491-61-4
Catalog Number:
AG000IFQ
Molecular Formula:
C7H10N3NaO6S
Molecular Weight:
287.2256
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%(HPLC)
In Stock USA
United States
$113
- +
25mg
98%(HPLC)
In Stock USA
United States
$172
- +
100mg
98%
In Stock USA
United States
$225
- +
250mg
98%
In Stock USA
United States
$400
- +
1g
98%
In Stock USA
United States
$1000
- +
Product Description
Catalog Number:
AG000IFQ
Chemical Name:
Avibactam sodium
CAS Number:
1192491-61-4
Molecular Formula:
C7H10N3NaO6S
Molecular Weight:
287.2256
MDL Number:
MFCD29472268
IUPAC Name:
sodium;[(2S,5R)-2-carbamoyl-7-oxo-1,6-diazabicyclo[3.2.1]octan-6-yl] sulfate
InChI:
InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
InChI Key:
RTCIKUMODPANKX-JBUOLDKXSA-M
SMILES:
NC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(=O)(=O)[O-].[Na+]
UNII:
9V824P8TAI
Properties
Complexity:
462  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
287.019g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
287.222g/mol
Monoisotopic Mass:
287.019g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
141A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Role of the Outer Membrane and Porins in Susceptibility of β-Lactamase-Producing Enterobacteriaceae to Ceftazidime-Avibactam. Antimicrobial agents and chemotherapy 20160301
Kinetics of avibactam inhibition against Class A, C, and D β-lactamases. The Journal of biological chemistry 20130927
Avibactam is a covalent, reversible, non-β-lactam β-lactamase inhibitor. Proceedings of the National Academy of Sciences of the United States of America 20120717
Anti-anaerobic activity of a new β-lactamase inhibitor NXL104 in combination with β-lactams and metronidazole. International journal of antimicrobial agents 20120601
In vitro activity of avibactam (NXL104) in combination with β-lactams against Gram-negative bacteria, including OXA-48 β-lactamase-producing Klebsiella pneumoniae. International journal of antimicrobial agents 20120101
New Delhi metallo-β-lactamase (NDM-1): an update. Journal of chemotherapy (Florence, Italy) 20111001
In vitro activity of ceftazidime+NXL104 against Pseudomonas aeruginosa and other non-fermenters. The Journal of antimicrobial chemotherapy 20101101
In vitro activity of the {beta}-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases. The Journal of antimicrobial chemotherapy 20090801
Properties