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Epristeride

CAS No.:
119169-78-7
Catalog Number:
AG000I9P
Molecular Formula:
C25H37NO3
Molecular Weight:
399.5662
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$473
- +
10mg
99%
1 week
United States
$723
- +
25mg
99%
1 week
United States
$1390
- +
Product Description
Catalog Number:
AG000I9P
Chemical Name:
Epristeride
CAS Number:
119169-78-7
Molecular Formula:
C25H37NO3
Molecular Weight:
399.5662
MDL Number:
MFCD00864172
IUPAC Name:
(8S,9S,10R,13S,14S,17S)-17-(tert-butylcarbamoyl)-10,13-dimethyl-2,7,8,9,11,12,14,15,16,17-decahydro-1H-cyclopenta[a]phenanthrene-3-carboxylic acid
InChI:
InChI=1S/C25H37NO3/c1-23(2,3)26-21(27)20-9-8-18-17-7-6-16-14-15(22(28)29)10-12-24(16,4)19(17)11-13-25(18,20)5/h6,14,17-20H,7-13H2,1-5H3,(H,26,27)(H,28,29)/t17-,18-,19-,20+,24-,25-/m0/s1
InChI Key:
VAPSMQAHNAZRKC-PQWRYPMOSA-N
SMILES:
OC(=O)C1=CC2=CC[C@@H]3[C@@H]([C@]2(CC1)C)CC[C@]1([C@H]3CC[C@@H]1C(=O)NC(C)(C)C)C
UNII:
39517A04PS
Properties
Complexity:
788  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
6  
Defined Bond Stereocenter Count:
0
Exact Mass:
399.277g/mol
Formal Charge:
0
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
399.575g/mol
Monoisotopic Mass:
399.277g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
66.4A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.1  
Literature
Title Journal
Discovery of a novel hybrid from finasteride and epristeride as 5α-reductase inhibitor. Bioorganic & medicinal chemistry letters 20110101
Self organizing molecular field analysis on a series of human 5alpha-reductase inhibitors: unsaturated 3-carboxysteroid. European journal of medicinal chemistry 20091201
[Comparison of different drugs on the treatment of benign prostate hyperplasia]. Zhonghua wai ke za zhi [Chinese journal of surgery] 20070715
[Effect of large-dosage of 5alpha-reductase inhibitors on the spermatogenesis of male rats]. Zhonghua nan ke xue = National journal of andrology 20050901
Twelve-year follow up of a randomized prospective trial comparing bacillus Calmette-Guerin and epirubicin as adjuvant therapy in superficial bladder cancer. International journal of urology : official journal of the Japanese Urological Association 20050501
Comparative study of human steroid 5alpha-reductase isoforms in prostate and female breast skin tissues: sensitivity to inhibition by finasteride and epristeride. Life sciences 20020531
Effect of epristeride on the expression of IGF-1 and TGF-beta receptors in androgen-induced castrated rat prostate. Experimental biology and medicine (Maywood, N.J.) 20011101
Inhibition of regrowth of prostatic glandular cells by epristeride. Acta pharmacologica Sinica 20010901
Properties