Name: Name:5-{2-Amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl}-N-tert-butylpyridine-3-sulfonamide
Brand: Angene
SKU: AG000HBZ
Rating: 90 (10 reviews)

5-{2-Amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl}-N-tert-butylpyridine-3-sulfonamide

CAS No.:

1159824-67-5

Catalog Number:

AG000HBZ

Molecular Formula:

C15H17FN6O2S

Molecular Weight:

364.3979

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

5mg

≥98%

1 week

United States

$168

- +

10mg

≥98%

1 week

United States

$268

- +

25mg

≥98%

1 week

United States

$557

- +

50mg

≥98%

1 week

United States

$946

- +

Product Description

Catalog Number:

AG000HBZ

Chemical Name:

5-{2-Amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl}-N-tert-butylpyridine-3-sulfonamide

CAS Number:

1159824-67-5

Molecular Formula:

C15H17FN6O2S

Molecular Weight:

364.3979

MDL Number:

MFCD22417090

IUPAC Name:

5-(2-amino-8-fluoro-[1,2,4]triazolo[1,5-a]pyridin-6-yl)-N-tert-butylpyridine-3-sulfonamide

InChI:

InChI=1S/C15H17FN6O2S/c1-15(2,3)21-25(23,24)11-4-9(6-18-7-11)10-5-12(16)13-19-14(17)20-22(13)8-10/h4-8,21H,1-3H3,(H2,17,20)

InChI Key:

RXRZPHQBTHQXSV-UHFFFAOYSA-N

SMILES:

Nc1nn2c(n1)c(F)cc(c2)c1cncc(c1)S(=O)(=O)NC(C)(C)C

Properties

Complexity:

578

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

364.112g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

364.399g/mol

Monoisotopic Mass:

364.112g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

124A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

Literature

Title	Journal
Discovery of 5-(2-amino-[1,2,4]triazolo[1,5-a]pyridin-7-yl)-N-(tert-butyl)pyridine-3-sulfonamide (CZC24758), as a potent, orally bioavailable and selective inhibitor of PI3K for the treatment of inflammatory disease.	Bioorganic & medicinal chemistry letters 20120715
A selective inhibitor reveals PI3Kγ dependence of T(H)17 cell differentiation.	Nature chemical biology 20120429

Properties