Home Halogens Mercury, chloromethyl- (8CI,9CI)

Mercury, chloromethyl- (8CI,9CI)

CAS No.:
115-09-3
Catalog Number:
AG000FK1
Molecular Formula:
CH2ClHg
Molecular Weight:
250.0696
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Purity
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Product Description
Catalog Number:
AG000FK1
Chemical Name:
Mercury, chloromethyl- (8CI,9CI)
CAS Number:
115-09-3
Molecular Formula:
CH2ClHg
Molecular Weight:
250.0696
MDL Number:
MFCD00013592
IUPAC Name:
chloro(methyl)mercury
InChI:
InChI=1S/CH3.ClH.Hg/h1H3;1H;/q;;+1/p-1
InChI Key:
BABMCXWQNSQAOC-UHFFFAOYSA-M
SMILES:
ClC[Hg]
EC Number:
204-064-2
NSC Number:
19998
Properties
Complexity:
4.8  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
251.963g/mol
Formal Charge:
0
Heavy Atom Count:
3  
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
251.077g/mol
Monoisotopic Mass:
251.963g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
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Methylmercury alters proliferation, migration, and antioxidant capacity in human HTR8/SV-neo trophoblast cells. Reproductive toxicology (Elmsford, N.Y.) 20180601
Methylmercury Affects the Expression of Hypothalamic Neuropeptides That Control Body Weight in C57BL/6J Mice. Toxicological sciences : an official journal of the Society of Toxicology 20180601
Delayed neurochemical effects of prenatal exposure to MeHg in the cerebellum of developing rats. Toxicology letters 20180301
Methylmercury exposure causes a persistent inhibition of myogenin expression and C2C12 myoblast differentiation. Toxicology 20180115
Developmental neurotoxicity of the hippocampus following in utero exposure to methylmercury: impairment in cell signaling. Archives of toxicology 20180101
Methylmercury promotes prostacyclin release from cultured human brain microvascular endothelial cells via induction of cyclooxygenase-2 through activation of the EGFR-p38 MAPK pathway by inhibiting protein tyrosine phosphatase 1B activity. Toxicology 20171201
Zuotai and HgS differ from HgCl(2) and methyl mercury in Hg accumulation and toxicity in weanling and aged rats. Toxicology and applied pharmacology 20170915
Methylmercury augments Nrf2 activity by downregulation of the Src family kinase Fyn. Neurotoxicology 20170901
Mercury exposure induces cytoskeleton disruption and loss of renal function through epigenetic modulation of MMP9 expression. Toxicology 20170701
Methylmercury induces an initial increase in GABA-evoked currents in Xenopus oocytes expressing α(1) and α(6) subunit-containing GABA(A) receptors. Neurotoxicology 20170501
Activation of interleukin-6 and -8 expressions by methylmercury in human U937 macrophages involves RelA and p50. Journal of applied toxicology : JAT 20170501
Editor's Highlight: Glutathione S-Transferase Activity Moderates Methylmercury Toxicity During Development in Drosophila. Toxicological sciences : an official journal of the Society of Toxicology 20170501
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Atg5-dependent autophagy plays a protective role against methylmercury-induced cytotoxicity. Toxicology letters 20161116
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Mitochondrial thioredoxin reductase inhibition, selenium status, and Nrf-2 activation are determinant factors modulating the toxicity of mercury compounds. Free radical biology & medicine 20140801
Excitotoxicity and oxidative damages induced by methylmercury in rat cerebral cortex and the protective effects of tea polyphenols. Environmental toxicology 20140301
Transcriptome-based functional classifiers for direct immunotoxicity. Archives of toxicology 20140301
Developmental stage dependent neural stem cells sensitivity to methylmercury chloride on different biofunctional surfaces. Toxicology in vitro : an international journal published in association with BIBRA 20140201
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Protective effects of diphenyl diselenide in a mouse model of brain toxicity. Chemico-biological interactions 20131025
Methylmercury exposure increases lipocalin related (lpr) and decreases activated in blocked unfolded protein response (abu) genes and specific miRNAs in Caenorhabditis elegans. Toxicology letters 20131024
miRNA expression profiling in a human stem cell-based model as a tool for developmental neurotoxicity testing. Cell biology and toxicology 20130801
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Gene responses in the central nervous system of zebrafish embryos exposed to the neurotoxicant methyl mercury. Environmental science & technology 20130402
A 3-dimensional human embryonic stem cell (hESC)-derived model to detect developmental neurotoxicity of nanoparticles. Archives of toxicology 20130401
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N-acetyl cysteine treatment reduces mercury-induced neurotoxicity in the developing rat hippocampus. Journal of neuroscience research 20120401
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The chemokine CCL2 protects against methylmercury neurotoxicity. Toxicological sciences : an official journal of the Society of Toxicology 20120101
Activation of TRPC cationic channels by mercurial compounds confers the cytotoxicity of mercury exposure. Toxicological sciences : an official journal of the Society of Toxicology 20120101
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Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects. Neurotoxicology 20071101
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Human serum albumin-mercurial species interactions. Journal of proteome research 20070601
Cell death and cytotoxic effects in YAC-1 lymphoma cells following exposure to various forms of mercury. Toxicology 20070227
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Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo. Genome biology 20070101
Phospholipase A2 activation regulates cytotoxicity of methylmercury in vascular endothelial cells. International journal of toxicology 20070101
Cytoprotective responses in the Mediterranean mussel exposed to Hg2+ and CH3Hg+. Biochemical and biophysical research communications 20061222
Methylmercury induces activation of Notch signaling. Neurotoxicology 20061201
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Cerebellar thiol status and motor deficit after lactational exposure to methylmercury. Environmental research 20060901
Cytotoxicity of dental composite (co)monomers and the amalgam component Hg(2+) in human gingival fibroblasts. Archives of toxicology 20060801
Cell death effects of resin-based dental material compounds and mercurials in human gingival fibroblasts. Archives of toxicology 20060601
Estradiol reduces cumulative mercury and associated disturbances in the hypothalamus-pituitary axis of ovariectomized rats. Ecotoxicology and environmental safety 20060301
Losses of immunoreactive parvalbumin amacrine and immunoreactive alphaprotein kinase C bipolar cells caused by methylmercury chloride intoxication in the retina of the tropical fish Hoplias malabaricus. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060301
Expression of c-fos in rat brain as a prelude marker of central nervous system injury in response to methylmercury-stimulation. Biomedical and environmental sciences : BES 20060201
Methylmercury alters the in vitro uptake of glutamate in GLAST- and GLT-1-transfected mutant CHO-K1 cells. Biological trace element research 20051201
Subchronic effects of methylmercury on plasma and organ biochemistries in great egret nestlings. Environmental toxicology and chemistry 20051201
Very low levels of methylmercury induce cell death of cultured rat cerebellar neurons via calpain activation. Toxicology 20050915
Salicylic acid triggers genotoxic adaptation to methyl mercuric chloride and ethyl methane sulfonate, but not to maleic hydrazide in root meristem cells of Allium cepa L. Mutation research 20050307
Effects of mercuric chloride on glucose transport in 3T3-L1 adipocytes. Toxicology in vitro : an international journal published in association with BIBRA 20050301
Methylmercury increases S100B content in rat cerebrospinal fluid. Environmental toxicology and pharmacology 20050201
The study of gap junctional intercellular communication in keratinocytes as screening of promoter effect induced by industrial and environmental toxic substances. La Medicina del lavoro 20050101
Mitochondrial viability and apoptosis induced by aluminum, mercuric mercury and methylmercury in cell lines of neural origin. Archives of toxicology 20041001
A new ultrasound protocol for extrusion of coelomocyte cells from the earthworm Eisenia fetida. Ecotoxicology and environmental safety 20040901
Acute exposure to methylmercury causes Ca2+ dysregulation and neuronal death in rat cerebellar granule cells through an M3 muscarinic receptor-linked pathway. Toxicological sciences : an official journal of the Society of Toxicology 20040701
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Differential effects of mercury, lead, and cadmium on IL-2 production by Jurkat T cells. Clinical immunology (Orlando, Fla.) 20040601
Development of an in vitro blood-brain barrier model-cytotoxicity of mercury and aluminum. Toxicology and applied pharmacology 20040215
More on mercury content in fish. Science (New York, N.Y.) 20040206
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More on mercury content in fish. Science (New York, N.Y.) 20040206
Additive pro-oxidative effects of methylmercury and ebselen in liver from suckling rat pups. Toxicology letters 20040202
Both mercury and cadmium directly influence calcium homeostasis resulting from the suppression of scale bone cells: the scale is a good model for the evaluation of heavy metals in bone metabolism. Journal of bone and mineral metabolism 20040101
Influence of dopamine on flash visual evoked potentials (FVEP) in prenatally mercury intoxicated rats. Polish journal of pharmacology 20040101
Assessing the dose-dependency of allometric scaling performance using physiologically based pharmacokinetic modeling. Regulatory toxicology and pharmacology : RTP 20031201
Chronic dietary mercury exposure causes oxidative stress, brain lesions, and altered behaviour in Atlantic salmon (Salmo salar) parr. Aquatic toxicology (Amsterdam, Netherlands) 20031008
The chemical form of mercury in fish. Science (New York, N.Y.) 20030829
Disruption of postnatal progenitor migration and consequent abnormal pattern of glial distribution in the cerebrum following administration of methylmercury. Journal of neuropathology and experimental neurology 20030801
Persistence and prevention of aluminium- and paraquat-induced adaptive response to methyl mercuric chloride in plant cells in vivo. Mutation research 20030708
Organelle specific enzyme markers as indicators of methylmercury neurotoxicity and antidotal efficacy in mice. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20030601
Synergistic effects of H2O2 with components of dental restorative materials on gluconeogenesis in rat kidney tubules. Biomaterials 20030501
Methylmercury-induced reactive oxygen species formation in neonatal cerebral astrocytic cultures is attenuated by antioxidants. Brain research. Molecular brain research 20030131
Effect of methylmercury on histamine release from rat mast cells. Archives of toxicology 20030101
Effects of aqueous extracts of Halimeda incrassata (Ellis) Lamouroux and Bryothamnion triquetrum (S.G.Gmelim) Howe on hydrogen peroxide and methyl mercury-induced oxidative stress in GT1-7 mouse hypothalamic immortalized cells. Phytomedicine : international journal of phytotherapy and phytopharmacology 20030101
Neuronal migration disturbance and consequent cytoarchitecture in the cerebral cortex following transplacental administration of methylmercury. Acta neuropathologica 20021001
Identification of a mechanism by which the methylmercury antidotes N-acetylcysteine and dimercaptopropanesulfonate enhance urinary metal excretion: transport by the renal organic anion transporter-1. Molecular pharmacology 20021001
Mercury-induced apoptosis in human lymphocytes: caspase activation is linked to redox status. Antioxidants & redox signaling 20020601
A ubiquitin-proteasome system is responsible for the protection of yeast and human cells against methylmercury. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020501
Cytotoxicity of ingredients of various dental materials and related compounds in L2- and A549 cells. Journal of biomedical materials research 20020101
Impairment of spermatogenesis in rats by methylmercury: involvement of stage- and cell- specific germ cell apoptosis. Toxicology 20011201
Antioxidant compounds and Ca(2+) pathway blockers differentially protect against methylmercury and mercuric chloride neurotoxicity. Journal of neuroscience research 20011001
Evaluation of methylmercury biotransformation using rat liver slices. Archives of toxicology 20010901
Different vulnerability of rat retinal cells to methylmercury exposure. Current eye research 20010901
Effects of methylmercury and organic acid mercurials on the disposition of exogenous selenium in rats. Toxicology and applied pharmacology 20010715
The effect of thiolate organic compounds on methylmercury accumulation and redistribution in sheepshead minnows, Cyprinodon variegatus. Environmental toxicology and chemistry 20010701
Methylmercury neurotoxicity in cultures of human neurons, astrocytes, neuroblastoma cells. Neurotoxicology 20010601
Methylmercury-mediated inhibition of 3H-D-aspartate transport in cultured astrocytes is reversed by the antioxidant catalase. Brain research 20010525
Abnormal auditory brainstem responses for mice treated with mercurial compounds: involvement of excessive nitric oxide. Toxicology 20010412
Cytotoxicity of dental composite components and mercury compounds in lung cells. Dental materials : official publication of the Academy of Dental Materials 20010301
Developmental exposure to methylmercury alters behavioral sensitivity to D-amphetamine and pentobarbital in adult rats. Neurotoxicology and teratology 20010101
Mercury-induced apoptosis in human lymphoid cells: evidence that the apoptotic pathway is mercurial species dependent. Environmental research 20001001
Methyl mercury-induced autoimmunity in mice. Toxicology and applied pharmacology 19990201
Expanded CTG repeats in myotonin protein kinase increase susceptibility to oxidative stress. Neuroreport 19980713
Induction by mercury compounds of brain metallothionein in rats: Hg0 exposure induces long-lived brain metallothionein. Archives of toxicology 19980301
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Selective inhibition of the mouse brain Mn-SOD by methylmercury. Environmental toxicology and pharmacology 19961220
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