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Home Other Building Blocks Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11β)-

Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11β)-

CAS No.:
1173-26-8
Catalog Number:
AG000E36
Molecular Formula:
C23H32O5
Molecular Weight:
388.4972
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Product Description
Catalog Number:
AG000E36
Chemical Name:
Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11-hydroxy-, (11β)-
CAS Number:
1173-26-8
Molecular Formula:
C23H32O5
Molecular Weight:
388.4972
MDL Number:
MFCD00010482
IUPAC Name:
[2-[(8S,9S,10R,11S,13S,14S,17S)-11-hydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] acetate
InChI:
InChI=1S/C23H32O5/c1-13(24)28-12-20(27)18-7-6-17-16-5-4-14-10-15(25)8-9-22(14,2)21(16)19(26)11-23(17,18)3/h10,16-19,21,26H,4-9,11-12H2,1-3H3/t16-,17-,18+,19-,21+,22-,23-/m0/s1
InChI Key:
WKQCPUMQBMFPLC-ZWFCQKKLSA-N
SMILES:
CC(=O)OCC(=O)[C@H]1CC[C@@H]2[C@]1(C)C[C@H](O)[C@H]1[C@H]2CCC2=CC(=O)CC[C@]12C
EC Number:
214-635-8
UNII:
KN17U0V6BL
NSC Number:
81764
Properties
Complexity:
739  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
7  
Defined Bond Stereocenter Count:
0
Exact Mass:
388.225g/mol
Formal Charge:
0
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
388.504g/mol
Monoisotopic Mass:
388.225g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
80.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.5  
Literature
Title Journal
α-fetoprotein involvement during glucocorticoid-induced precocious maturation in rat colon. World journal of gastroenterology 20110628
Effect of acute and chronic hypertension on short- and long-term spatial and avoidance memory in male rats. Pathophysiology : the official journal of the International Society for Pathophysiology 20100201
Development of SLN and NLC enriched hydrogels for transdermal delivery of nitrendipine: in vitro and in vivo characteristics. Drug development and industrial pharmacy 20090101
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. Chemical research in toxicology 20080401
Corticosterone impairs the mRNA expression and activity of 3beta- and 17beta-hydroxysteroid dehydrogenases in adult rat Leydig cells. Biochemistry and cell biology = Biochimie et biologie cellulaire 20061001
Effects of excess corticosterone on NADPH generating enzymes and glucose oxidation in Leydig cells of adult rats. Human & experimental toxicology 20060301
Chronic corticosterone treatment increases the endocannabinoid 2-arachidonylglycerol in the rat amygdala. European journal of pharmacology 20051228
Corticosterone 21-acetate in vivo induces acute stress in chicken thymus: cell proliferation, apoptosis and cytokine responses. Histology and histopathology 20040701
Repeated handling, restraint, or chronic crowding impair the hypothalamic-pituitary-adrenocortical response to acute restraint stress. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030901
Properties