Home Other Building Blocks methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine

methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine

CAS No.:
116539-59-4
Catalog Number:
AG000CPW
Molecular Formula:
C18H19NOS
Molecular Weight:
297.4146
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
95%
In Stock USA
United States
$125
- +
1g
95%
In Stock USA
United States
$300
- +
5g
95%
In Stock USA
United States
$813
- +
Product Description
Catalog Number:
AG000CPW
Chemical Name:
methyl[(3S)-3-(naphthalen-1-yloxy)-3-(thiophen-2-yl)propyl]amine
CAS Number:
116539-59-4
Molecular Formula:
C18H19NOS
Molecular Weight:
297.4146
MDL Number:
MFCD06801358
IUPAC Name:
(3S)-N-methyl-3-naphthalen-1-yloxy-3-thiophen-2-ylpropan-1-amine
InChI:
InChI=1S/C18H19NOS/c1-19-12-11-17(18-10-5-13-21-18)20-16-9-4-7-14-6-2-3-8-15(14)16/h2-10,13,17,19H,11-12H2,1H3/t17-/m0/s1
InChI Key:
ZEUITGRIYCTCEM-KRWDZBQOSA-N
SMILES:
CNCC[C@@H](c1cccs1)Oc1cccc2c1cccc2
UNII:
O5TNM5N07U
Properties
Complexity:
312  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
297.119g/mol
Formal Charge:
0
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
297.416g/mol
Monoisotopic Mass:
297.119g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
49.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.3  
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'Tako-tsubo' cardiomyopathy and duloxetine use. Southern medical journal 20110501
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Examining the use of tramadol hydrochloride as an antidepressant. Experimental and clinical psychopharmacology 20110401
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Duloxetine for mild to moderate postprostatectomy incontinence: preliminary results of a randomised, placebo-controlled trial. European urology 20110101
Halothane-anesthetized rabbit: a new experimental model to test the effects of besipirdine and duloxetine on lower urinary tract function. Urologia internationalis 20110101
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Evidence-based interventional pain medicine according to clinical diagnoses. 18. Painful diabetic polyneuropathy. Pain practice : the official journal of World Institute of Pain 20110101
Real-world evaluation of health-care resource utilization and costs in employees with fibromyalgia treated with pregabalin or duloxetine. Pain practice : the official journal of World Institute of Pain 20110101
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Efficacy of antidepressants and benzodiazepines in minor depression: systematic review and meta-analysis. The British journal of psychiatry : the journal of mental science 20110101
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Retrospective audit on tolerability and efficacy of duloxetine for stress urinary incontinence. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20110101
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Should we treat depression with drugs or psychological interventions? A reply to Ioannidis. Philosophy, ethics, and humanities in medicine : PEHM 20110101
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Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial. Arthritis research & therapy 20110101
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Duloxetine-induced subcortical growth in a patient with major depressive disorder and panic disorder. The Journal of neuropsychiatry and clinical neurosciences 20110101
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Antidepressants: From MAOIs to SSRIs and more. Indian journal of psychiatry 20110101
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Review of the safety, efficacy, and side effect profile of asenapine in the treatment of bipolar 1 disorder. Patient preference and adherence 20110101
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Retrospective chart review of a referenced EEG database in assisting medication selection for treatment of depression in patients with eating disorders. Neuropsychiatric disease and treatment 20110101
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Permanent relief from intermittent cold stress-induced fibromyalgia-like abnormal pain by repeated intrathecal administration of antidepressants. Molecular pain 20110101
Adherence and persistence with branded antidepressants and generic SSRIs among managed care patients with major depressive disorder. ClinicoEconomics and outcomes research : CEOR 20110101
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Antinociceptive effect of an ethanolic extract of the aerial parts of Hilleria latifolia (Lam.) H. Walt. (Phytolaccaceae). Journal of pharmacy & bioallied sciences 20110101
Study of antinociceptive activity of SSRI (fluoxetine and escitalopram) and atypical antidepressants (venlafaxine and mirtazepine) and their interaction with morphine and naloxone in mice. Journal of pharmacy & bioallied sciences 20110101
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Neuropathic pain: a personal case reflection on a critical incident. Indian journal of palliative care 20110101
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Primary and repeat surgical treatment for female pelvic organ prolapse and incontinence in parous women in the UK: a register linkage study. BMJ open 20110101
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Takotsubo cardiomyopathy associated with titration of duloxetine. Texas Heart Institute journal 20110101
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Duloxetine contributing to a successful multimodal treatment program for peripheral femoral neuropathy and comorbid 'reactive depression' in an adolescent. Pain research & management 20110101
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Efficacy of duloxetine on painful physical symptoms in major depressive disorder for patients with clinically significant painful physical symptoms at baseline: a meta-analysis of 11 double-blind, placebo-controlled clinical trials. The primary care companion for CNS disorders 20110101
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Duloxetine versus placebo in patients with chronic low back pain: a 12-week, fixed-dose, randomized, double-blind trial. The journal of pain : official journal of the American Pain Society 20101201
A review of SSRIs and SNRIs in neuropathic pain. Expert opinion on pharmacotherapy 20101201
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The effect of coadministration of duloxetine on steady-state serum concentration of risperidone and aripiprazole: a study based on therapeutic drug monitoring data. Therapeutic drug monitoring 20101201
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Increased aripiprazole concentrations in an HIV-positive male concurrently taking duloxetine, darunavir, and ritonavir. The Annals of pharmacotherapy 20101101
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In vitro and in vivo evaluation of the effects of duloxetine on P-gp function. Human psychopharmacology 20101101
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The impact of CYP2D6-predicted phenotype on tamoxifen treatment outcome in patients with metastatic breast cancer. British journal of cancer 20100907
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Effects of adjunctive reboxetine in patients with duloxetine-resistant depression: a 12-week prospective study. Journal of psychopharmacology (Oxford, England) 20100801
Clinical outcome and tolerability of duloxetine in the treatment of major depressive disorder: a 12-week study with plasma levels. Journal of psychopharmacology (Oxford, England) 20100801
Escitalopram--translating molecular properties into clinical benefit: reviewing the evidence in major depression. Journal of psychopharmacology (Oxford, England) 20100801
Analytic model comparing the cost utility of TVT versus duloxetine in women with urinary stress incontinence. International urogynecology journal 20100801
The predictive value of pre-treatment cystometry in the outcome of women with mixed incontinence treated with duloxetine. European journal of obstetrics, gynecology, and reproductive biology 20100801
Analgesic effects of a substituted N-triazole oxindole (TROX-1), a state-dependent, voltage-gated calcium channel 2 blocker. The Journal of pharmacology and experimental therapeutics 20100801
Cost-effectiveness of duloxetine: the Stress Urinary Incontinence Treatment (SUIT) study. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100801
Alpha2-adrenoceptor blockade potentiates the effect of duloxetine on sneeze induced urethral continence reflex in rats. The Journal of urology 20100801
Pharmacological and clinical profile of newer antidepressants: implications for the treatment of elderly patients. Drugs & aging 20100801
Extrapyramidal symptoms associated with antidepressants--a review of the literature and an analysis of spontaneous reports. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists 20100801
Fibromyalgia and bipolar disorder: a potential problem? Bipolar disorders 20100801
Treating diabetic peripheral neuropathic pain. American family physician 20100715
[Evidence-based recommendations for the treatment of fibromyalgia syndrome]. Zeitschrift fur Rheumatologie 20100701
Escitalopram versus serotonin noradrenaline reuptake inhibitors as second step treatment for patients with major depressive disorder: a pooled analysis. International clinical psychopharmacology 20100701
Safety and tolerability of duloxetine in the acute management of diabetic peripheral neuropathic pain: analysis of pooled data from three placebo-controlled clinical trials. Expert opinion on drug safety 20100701
Non-length-dependent small fibre neuropathy. Confocal microscopy study of the corneal innervation. Journal of neurology, neurosurgery, and psychiatry 20100701
Duloxetine for the treatment of generalized social anxiety disorder: a preliminary randomized trial of increased dose to optimize response. CNS spectrums 20100701
The treatment of stress incontinence in men: part 2 of a series of articles on incontinence. Deutsches Arzteblatt international 20100701
Effects of antidepressants in patients with irritable bowel syndrome and comorbid depression. Clinical therapeutics 20100701
Urinary incontinence in the elderly: part 3 of a series of articles on incontinence. Deutsches Arzteblatt international 20100701
[Design, synthesis and antidepressive activity of duloxetine derivatives]. Yao xue xue bao = Acta pharmaceutica Sinica 20100701
Comparison of neurogenic effects of fluoxetine, duloxetine and running in mice. Brain research 20100623
Second generation N-(1,2-diphenylethyl)piperazines as dual serotonin and noradrenaline reuptake inhibitors: improving metabolic stability and reducing ion channel activity. Bioorganic & medicinal chemistry letters 20100615
Long-term safety, tolerability, and efficacy of duloxetine in the treatment of fibromyalgia. Seminars in arthritis and rheumatism 20100601
Duloxetine and care management treatment of older adults with comorbid major depressive disorder and chronic low back pain: results of an open-label pilot study. International journal of geriatric psychiatry 20100601
Relationship between TSH levels in the normal range and short-term duloxetine efficacy. Journal of affective disorders 20100601
Major Depressive Disorder in recovery and neuropsychological functioning: effects of selective serotonin reuptake inhibitor and dual inhibitor depression treatments on residual cognitive deficits in patients with Major Depressive Disorder in recovery. Journal of affective disorders 20100601
Failure to replicate genetic associations with antidepressant treatment response in duloxetine-treated patients. Biological psychiatry 20100601
Prescription patterns of antidepressants: findings from a US claims database. Current medical research and opinion 20100601
Emerging drugs for treatment of urinary incontinence. Expert opinion on emerging drugs 20100601
Relevance of norepinephrine-dopamine interactions in the treatment of major depressive disorder. CNS neuroscience & therapeutics 20100601
Comparative efficacy and harms of duloxetine, milnacipran, and pregabalin in fibromyalgia syndrome. The journal of pain : official journal of the American Pain Society 20100601
Medical management of trigeminal neuropathic pains. Expert opinion on pharmacotherapy 20100601
Efficacy and safety of duloxetine in patients with chronic low back pain. Spine 20100601
Update on antithrombotic therapy for stroke prevention in atrial fibrillation. Current treatment options in cardiovascular medicine 20100601
Lymphocytic colitis under treatment with duloxetine. Zeitschrift fur Gastroenterologie 20100601
Pharmacologic management of chronic pain. The Korean journal of pain 20100601
Fibromyalgia syndrome: practical strategies for improving diagnosis and patient outcomes. The American journal of medicine 20100601
Drug treatment of obsessive-compulsive disorder. Dialogues in clinical neuroscience 20100601
Why do we need multifunctional neuroprotective and neurorestorative drugs for Parkinson's and Alzheimer's diseases as disease modifying agents. Experimental neurobiology 20100601
Effects of selective serotonin reuptake and dual serotonergic-noradrenergic reuptake treatments on attention and executive functions in patients with major depressive disorder. Psychiatry research 20100530
Spinal mechanism of standard analgesics: evaluation using mouse models of allodynia. European journal of pharmacology 20100525
Depression as an initial feature of systemic lupus erythematosus? A case report. Journal of medicine and life 20100515
First preliminary results of a single case report: duloxetine might improve some symptoms of attention-deficit hyperactivity disorder. European psychiatry : the journal of the Association of European Psychiatrists 20100501
Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. Molecular pharmacology 20100501
Urinary flow and urinary symptoms in elderly males exposed to either escitalopram or duloxetine. Current medical research and opinion 20100501
Duloxetine 60 mg/day for the prevention of depressive recurrences: post hoc analyses from a recurrence prevention study. International journal of clinical practice 20100501
Heterocyclic cycloalkanol ethylamines as norepinephrine reuptake inhibitors. Bioorganic & medicinal chemistry letters 20100501
Adverse events, toxicity and post-mortem data on duloxetine: case reports and literature survey. Journal of forensic and legal medicine 20100501
Effects of varying degrees of renal impairment on the pharmacokinetics of duloxetine: analysis of a single-dose phase I study and pooled steady-state data from phase II/III trials. Clinical pharmacokinetics 20100501
Profile of adverse events with duloxetine treatment: a pooled analysis of placebo-controlled studies. Drug safety 20100501
Escitalopram 20 mg versus duloxetine 60 mg for the treatment of chronic low back pain. Expert opinion on pharmacotherapy 20100501
Use of duloxetine in patients with an anxiety disorder, or with comorbid anxiety and major depressive disorder: a review of the literature. Expert opinion on pharmacotherapy 20100501
Managing diabetic peripheral neuropathic pain in primary care. The Journal of family practice 20100501
Maintenance of effect of duloxetine in patients with chronic low back pain: a 41-week uncontrolled, dose-blinded study. Pain medicine (Malden, Mass.) 20100501
Molecular basis and current treatment for alcoholic liver disease. International journal of environmental research and public health 20100501
Criteria for evaluation of disease extent by (123)I-metaiodobenzylguanidine scans in neuroblastoma: a report for the International Neuroblastoma Risk Group (INRG) Task Force. British journal of cancer 20100427
Pregabalin in fibromyalgia: meta-analysis of efficacy and safety from company clinical trial reports. Rheumatology (Oxford, England) 20100401
New drug treatments for urinary incontinence. Maturitas 20100401
Cost effectiveness of pregabalin in the treatment of fibromyalgia from a UK perspective. Current medical research and opinion 20100401
Chronic thromboembolic pulmonary hypertension. Current treatment options in cardiovascular medicine 20100401
[Conservative management of postoperative urinary incontinence in men]. Der Urologe. Ausg. A 20100401
Mixed incontinence: current evidence and future perspectives. Neurourology and urodynamics 20100401
Duloxetine related hypersexuality: a case report. Progress in neuro-psychopharmacology & biological psychiatry 20100317
Antidepressant pharmaceuticals in two U.S. effluent-impacted streams: occurrence and fate in water and sediment, and selective uptake in fish neural tissue. Environmental science & technology 20100315
Determination of duloxetine hydrochloride in the presence of process and degradation impurities by a validated stability-indicating RP-LC method. Journal of pharmaceutical and biomedical analysis 20100311
1-(Indolin-1-yl)-1-phenyl-3-propan-2-olamines as potent and selective norepinephrine reuptake inhibitors. Journal of medicinal chemistry 20100311
[Focus on treatment success of depressed patients. Early and significant pain reduction improves chances for remission]. MMW Fortschritte der Medizin 20100304
Efficacy and tolerability of duloxetine in the treatment of patients with borderline personality disorder: a pilot study. Journal of psychopharmacology (Oxford, England) 20100301
Patient reported outcomes tools in an observational study of female stress urinary incontinence. Neurourology and urodynamics 20100301
Reductions in stress urinary incontinence episodes: what is clinically important for women? Neurourology and urodynamics 20100301
Diminished neural processing of aversive and rewarding stimuli during selective serotonin reuptake inhibitor treatment. Biological psychiatry 20100301
Oculopalatal tremor explained by a model of inferior olivary hypertrophy and cerebellar plasticity. Brain : a journal of neurology 20100301
Effects of duloxetine in treatment-refractory men with posttraumatic stress disorder. Pharmacopsychiatry 20100301
Prospective drug safety monitoring using the UK primary-care General Practice Research Database: theoretical framework, feasibility analysis and extrapolation to future scenarios. Drug safety 20100301
[The effects of duloxetine on beta-actin stress response in rat brain]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20100301
Management of depression in the presence of pain symptoms. Psychiatria Danubina 20100301
Psychiatric pharmacogenomic testing in clinical practice. Dialogues in clinical neuroscience 20100301
Antidepressant-Induced Sexual Dysfunction among Newer Antidepressants in a Naturalistic Setting. Psychiatry investigation 20100301
The clinical importance of changes in the 0 to 10 numeric rating scale for worst, least, and average pain intensity: analyses of data from clinical trials of duloxetine in pain disorders. The journal of pain : official journal of the American Pain Society 20100201
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats. Neuropharmacology 20100201
Duloxetine related effects of brain structure on a patient of major depressive disorder with panic disorder. Progress in neuro-psychopharmacology & biological psychiatry 20100201
Tinnitus in postherpetic neuralgia. The journal of headache and pain 20100201
Comparison of milnacipran, duloxetine and pregabalin in the formalin pain test and in a model of stress-induced ultrasonic vocalizations in rats. Neuroscience research 20100201
Short- and long-term efficacy and safety of duloxetine in women with predominant stress urinary incontinence. Current medical research and opinion 20100201
Duloxetine-modulating effects of brain structure in major depressive disorder with panic disorder. Journal of clinical psychopharmacology 20100201
Duloxetine in the treatment of osteoarthritis knee pain. Current psychiatry reports 20100201
[Treatment of neuropathies]. Orvosi hetilap 20100110
Economic evaluation of duloxetine versus serotonin selective reuptake inhibitors and venlafaxine XR in treating major depressive disorder in Scotland. Journal of affective disorders 20100101
The Arc of synaptic memory. Experimental brain research 20100101
Patient characteristics impacting health state index scores, measured by the EQ-5D of females with stress urinary incontinence symptoms. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101
Randomized placebo-controlled double-blind clinical trial of cannabis-based medicinal product (Sativex) in painful diabetic neuropathy: depression is a major confounding factor. Diabetes care 20100101
Anxiety does not predict response to duloxetine in major depression: results of a pooled analysis of individual patient data from 11 placebo-controlled trials. Depression and anxiety 20100101
Study on enantiomeric separation of basic drugs by NACE in methanol-based medium using erythromycin lactobionate as a chiral selector. Electrophoresis 20100101
Pharmacological treatment of fibromyalgia syndrome: new developments. Drugs 20100101
Drugs to treat fibromyalgia - the transatlantic difference. Current opinion in investigational drugs (London, England : 2000) 20100101
A case study of salami slicing: pooled analyses of duloxetine for depression. Psychotherapy and psychosomatics 20100101
Desvenlafaxine succinate: a newer antidepressant for the treatment of depression and somatic symptoms. Postgraduate medicine 20100101
The market lifecycle of duloxetine for urinary incontinence in Norway. Acta obstetricia et gynecologica Scandinavica 20100101
Selective serotonin reuptake inhibitors and breast cancer mortality in women receiving tamoxifen: a population based cohort study. BMJ (Clinical research ed.) 20100101
Expression genetics identifies spinal mechanisms supporting formalin late phase behaviors. Molecular pain 20100101
A closer look at the baseline-observation-carried-forward (BOCF). Patient preference and adherence 20100101
Selective serotonin reuptake inhibitors potentiate the rapid antidepressant-like effects of serotonin4 receptor agonists in the rat. PloS one 20100101
Rationale and design of the randomised clinical trial comparing early medication change (EMC) strategy with treatment as usual (TAU) in patients with major depressive disorder--the EMC trial. Trials 20100101
Medically unexplained pain complaints are associated with underlying unrecognized mood disorders in primary care. BMC family practice 20100101
Antidepressants are a rational complementary therapy for the treatment of Alzheimer's disease. Molecular neurodegeneration 20100101
A presumed case of phantom limb pain treated successfully with duloxetine and pregabalin. General hospital psychiatry 20100101
Autonomic dysfunction presenting as postural orthostatic tachycardia syndrome in patients with multiple sclerosis. International journal of medical sciences 20100101
Stability-indicating RP-HPLC method development and validation for duloxetine hydrochloride in tablets. Journal of AOAC International 20100101
Antipsychotic treatments for the elderly: efficacy and safety of aripiprazole. Neuropsychiatric disease and treatment 20100101
Continuation treatment of major depressive disorder: is there a case for duloxetine? Drug design, development and therapy 20100101
Reporting bias in medical research - a narrative review. Trials 20100101
Correction of venlafaxine- and duloxetine-induced transaminase elevations with desvenlafaxine in a patient with Gilbert's syndrome. CNS spectrums 20100101
The relationship between average daily dose, medication adherence, and health-care costs among diabetic peripheral neuropathic pain patients initiated on duloxetine therapy. Pain practice : the official journal of World Institute of Pain 20100101
Practical application of cure mixture model for long-term censored survivor data from a withdrawal clinical trial of patients with major depressive disorder. BMC medical research methodology 20100101
[Duloxetine in the treatment of chronic migraine]. Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20100101
Validity and responsiveness of the EQ-5D in assessing and valuing health status in patients with anxiety disorders. Health and quality of life outcomes 20100101
Psychopharmacological neuroprotection in neurodegenerative disease: heuristic clinical applications. The Journal of neuropsychiatry and clinical neurosciences 20100101
Comparison of the consumption of antidepressants in the immigrant and native populations in a Spanish health region: an observational study. BMC public health 20100101
The effect of Neuragen PN on neuropathic pain: A randomized, double blind, placebo controlled clinical trial. BMC complementary and alternative medicine 20100101
The relationship between depression, anxiety, and cardiovascular outcomes in patients with acute coronary syndromes. Neuropsychiatric disease and treatment 20100101
Role and rationale for the use of milnacipran in the management of fibromyalgia. Neuropsychiatric disease and treatment 20100101
Hypolocomotion, asymmetrically directed behaviors (licking, lifting, flinching, and shaking) and dynamic weight bearing (gait) changes are not measures of neuropathic pain in mice. Molecular pain 20100101
Atypical depression is more common than melancholic in fibromyalgia: an observational cohort study. BMC musculoskeletal disorders 20100101
Pain response profile of patients with fibromyalgia treated with duloxetine. The Clinical journal of pain 20100101
Stem cell-based neuroprotective and neurorestorative strategies. International journal of molecular sciences 20100101
Fibromyalgia syndrome: a discussion of the syndrome and pharmacotherapy. American journal of therapeutics 20100101
Efficacy and acceptability of selective serotonin reuptake inhibitors for the treatment of depression in Parkinson's disease: a systematic review and meta-analysis of randomized controlled trials. BMC neurology 20100101
Identification of symptom and functional domains that fibromyalgia patients would like to see improved: a cluster analysis. BMC musculoskeletal disorders 20100101
Pregabalin in fibromyalgia--responder analysis from individual patient data. BMC musculoskeletal disorders 20100101
Localized 1H-NMR spectroscopy in patients with fibromyalgia: a controlled study of changes in cerebral glutamate/glutamine, inositol, choline, and N-acetylaspartate. Arthritis research & therapy 20100101
Effect of duloxetine in patients with fibromyalgia: tiredness subgroups. Arthritis research & therapy 20100101
Long lasting pain hypersensitivity following ligation of the tendon of the masseter muscle in rats: a model of myogenic orofacial pain. Molecular pain 20100101
The effect of newer serotonin-noradrenalin antidepressants on cytokine production: a review of the current literature. International journal of immunopathology and pharmacology 20100101
Augmentation of clozapine with aripiprazole in severe psychotic bipolar and schizoaffective disorders: a pilot study. Clinical practice and epidemiology in mental health : CP & EMH 20100101
Perioperative care of an adolescent with postural orthostatic tachycardia syndrome. Saudi journal of anaesthesia 20100101
State-of-the-Art Management of Complications of Myeloma and Its Treatment. Advances in hematology 20100101
Management of generalized anxiety disorder in primary care: identifying the challenges and unmet needs. Primary care companion to the Journal of clinical psychiatry 20100101
Duloxetine may improve some symptoms of attention-deficit/hyperactivity disorder. Primary care companion to the Journal of clinical psychiatry 20100101
Ethical issues in scientific publication. Indian journal of orthopaedics 20100101
Cost effectiveness of escitalopram versus SNRIs in second-step treatment of major depressive disorder in Sweden. Journal of medical economics 20100101
Environmental enrichment induces behavioral recovery and enhanced hippocampal cell proliferation in an antidepressant-resistant animal model for PTSD. PloS one 20100101
[Pharmacologic therapy in peripheral diabetic polyneuropathy]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20100101
[Duloxetine]. Revue de l'infirmiere 20100101
A case report of transient but clinically relevant interaction between methadone and duloxetine: a reply to McCance-Katz et al. The American journal on addictions 20100101
Effects of aquajogging in obese adults: a pilot study. Journal of obesity 20100101
Trazodone for the treatment of fibromyalgia: an open-label, 12-week study. BMC musculoskeletal disorders 20100101
An overview of curcumin in neurological disorders. Indian journal of pharmaceutical sciences 20100101
Remission of severe restless legs syndrome and periodic limb movements in sleep after bilateral excision of multiple foot neuromas: a case report. Journal of medical case reports 20100101
Suicidality: risk factors and the effects of antidepressants. The example of parallel reduction of suicidality and other depressive symptoms during treatment with the SNRI, milnacipran. Neuropsychiatric disease and treatment 20100101
Milnacipran: a unique antidepressant? Neuropsychiatric disease and treatment 20100101
Getting the balance right: Established and emerging therapies for major depressive disorders. Neuropsychiatric disease and treatment 20100101
Management of male urinary incontinence. Indian journal of urology : IJU : journal of the Urological Society of India 20100101
Slings in iatrogenic male incontinence: Current status. Indian journal of urology : IJU : journal of the Urological Society of India 20100101
Duloxetine: a review of its pharmacology and use in chronic pain management. Regional anesthesia and pain medicine 20100101
Duloxetine versus venlafaxine in the treatment of unipolar and bipolar depression. La Clinica terapeutica 20100101
Efficacy and safety of duloxetine in fibromyalgia. La Clinica terapeutica 20100101
Duloxetine May Improve Tourette's Syndrome: A Case Report. Primary care companion to the Journal of clinical psychiatry 20100101
Alexithymia, emotion processing and social anxiety in adults with ADHD. European journal of medical research 20100101
Improvement of social adaptation in depression with serotonin and norepinephrine reuptake inhibitors. Neuropsychiatric disease and treatment 20100101
Evaluation of the safety and efficacy of pregabalin in older patients with neuropathic pain: results from a pooled analysis of 11 clinical studies. BMC family practice 20100101
Optimal management of perimenopausal depression. International journal of women's health 20100101
Evaluation of healthcare resource utilization and costs in employees with pain associated with diabetic peripheral neuropathy treated with pregabalin or duloxetine. Journal of medical economics 20100101
Pregabalin, the lidocaine plaster and duloxetine in patients with refractory neuropathic pain: a systematic review. BMC neurology 20100101
Duloxetine-related tardive dystonia and tardive dyskinesia: a case report. General hospital psychiatry 20100101
Duloxetine treatment of long-term ketamine abuse-related lower urinary tract symptoms: a case report. General hospital psychiatry 20100101
Proteasome inhibition and its therapeutic potential in multiple myeloma. Biologics : targets & therapy 20100101
Gene expression profile analysis of genes in rat hippocampus from antidepressant treated rats using DNA microarray. BMC neuroscience 20100101
Microstructural abnormalities in subcortical reward circuitry of subjects with major depressive disorder. PloS one 20100101
Duloxetine in military posttraumatic stress disorder. Psychopharmacology bulletin 20100101
A new strategy for antidepressant prescription. Frontiers in neuroscience 20100101
Comparison of the pharmacokinetic properties of vancomycin, linezolid, tigecyclin, and daptomycin. European journal of medical research 20100101
Pharmacological treatment of fibromyalgia. Clinical and experimental rheumatology 20100101
Development and validation of a stability-indicating RP-HPLC method for duloxetine hydrochloride in its bulk and tablet dosage form. Scientia pharmaceutica 20100101
3D-QSAR design of new escitalopram derivatives for the treatment of major depressive disorders. Scientia pharmaceutica 20100101
The disturbance of gaze in progressive supranuclear palsy: implications for pathogenesis. Frontiers in neurology 20100101
Milnacipran for the management of fibromyalgia syndrome. Journal of pain research 20100101
An open-label, non-randomized comparison of venlafaxine and gabapentin as monotherapy or adjuvant therapy in the management of neuropathic pain in patients with peripheral neuropathy. Journal of pain research 20100101
Pregabalin for the management of fibromyalgia syndrome. Journal of pain research 20100101
New and emerging therapeutic agents for the treatment of fibromyalgia: an update. Journal of pain research 20100101
Pilot study: rapidly cycling hypobaric pressure improves pain after 5 days in adiposis dolorosa. Journal of pain research 20100101
Investigational pharmacology for low back pain. Journal of pain research 20100101
Pharmacological treatment of painful HIV-associated sensory neuropathy: a systematic review and meta-analysis of randomised controlled trials. PloS one 20100101
Pregabalin in treatment-refractory fibromyalgia. The open rheumatology journal 20100101
Stress degradation studies and kinetic determinations of duloxetine enteric-coated pellets by HPLC. Journal of AOAC International 20100101
Lactating mother and psychotropic drugs. Mens sana monographs 20100101
Maintaining efficacy in the treatment of diabetic peripheral neuropathic pain: role of duloxetine. Diabetes, metabolic syndrome and obesity : targets and therapy 20100101
Challenges in the pharmacotherapy of urogenital disorders. Frontiers in pharmacology 20100101
Research on antidepressants in India. Indian journal of psychiatry 20100101
Pathway-Targeted Pharmacogenomics of CYP1A2 in Human Liver. Frontiers in pharmacology 20100101
Extreme thermal sensitivity and pain-induced sensitization in a fibromyalgia patient. Pain research and treatment 20100101
[Expel the fear of pain. Breaking of chronicity by re-learning]. MMW Fortschritte der Medizin 20091210
Therapeutic drug monitoring of seven psychotropic drugs and four metabolites in human plasma by HPLC-MS. Journal of pharmaceutical and biomedical analysis 20091205
Duloxetine, a centrally acting analgesic, in the treatment of patients with osteoarthritis knee pain: a 13-week, randomized, placebo-controlled trial. Pain 20091201
The short- and long-term effect of duloxetine on painful physical symptoms in patients with generalized anxiety disorder: results from three clinical trials. Journal of anxiety disorders 20091201
Effects of duloxetine on the pharmacodynamics and pharmacokinetics of warfarin at steady state in healthy subjects. Journal of clinical pharmacology 20091201
Differential inhibitory effects of drugs acting at the noradrenaline and 5-hydroxytryptamine transporters in rat and human neocortical synaptosomes. British journal of pharmacology 20091201
How are women with SUI-symptoms treated with duloxetine in real life practice? - preliminary results from a large observational study in Germany. International journal of clinical practice 20091201
Quetiapine XR efficacy and tolerability as monotherapy and as adjunctive treatment to conventional antidepressants in the acute and maintenance treatment of major depressive disorder: a review of registration trials. Expert opinion on pharmacotherapy 20091201
Further strategies for treating fibromyalgia: the role of serotonin and norepinephrine reuptake inhibitors. The American journal of medicine 20091201
[Efficacy of escitalopram and severity of depression: new data]. L'Encephale 20091201
[Pharmacological treatment for stress urinary incontinence in prostate cancer]. Archivos espanoles de urologia 20091201
Unexplained high fever in an elderly patient treated with clonidine, duloxetine, and atorvastatin. Clinical therapeutics 20091201
Serotonin syndrome in an octogenarian after switch from fluoxetine to duloxetine. Journal of the American Geriatrics Society 20091201
Association between Painful Physical Symptoms and Clinical Outcomes in Korean Patients with Major Depressive Disorder: A Three-Month Observational Study. Psychiatry investigation 20091201
A treatment algorithm for neuropathic pain: an update. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20091201
Serotonin-norepinephrine reuptake inhibitors for pain control: premise and promise. Current neuropharmacology 20091201
Duloxetine related binge eating behaviors: a case report. Progress in neuro-psychopharmacology & biological psychiatry 20091113
Duloxetine for major depressive episodes in the course of psychotic disorders: an observational clinical trial. Journal of psychopharmacology (Oxford, England) 20091101
Biogenic amine depletion causes chronic muscular pain and tactile allodynia accompanied by depression: A putative animal model of fibromyalgia. Pain 20091101
Plasma levels and cerebrospinal fluid penetration by duloxetine in a patient with a non-fatal overdose during a suicide attempt. The international journal of neuropsychopharmacology 20091101
Duloxetine for pathological laughing and crying. The international journal of neuropsychopharmacology 20091101
Use of duloxetine in pregnancy and lactation. The Annals of pharmacotherapy 20091101
What makes patients with fibromyalgia feel better? Correlations between Patient Global Impression of Improvement and changes in clinical symptoms and function: a pooled analysis of 4 randomized placebo-controlled trials of duloxetine. The Journal of rheumatology 20091101
Use of antidepressants for management of hot flashes. Pharmacotherapy 20091101
Painful diabetic neuropathy: advantage of novel drugs over old drugs? Diabetes care 20091101
Evaluation of anti-obesity activity of duloxetine in comparison with sibutramine along with its anti-depressant activity: an experimental study in obese rats. Canadian journal of physiology and pharmacology 20091101
Clinical aspects and management of fibromyalgia syndrome. Annals of the Academy of Medicine, Singapore 20091101
Abnormal gait, due to inflammation but not nerve injury, reflects enhanced nociception in preclinical pain models. Brain research 20091027
Highly enantioselective Friedel-Crafts reaction of thiophenes with glyoxylates: formal synthesis of duloxetine. Organic letters 20091015
Synthesis of 1,1-[1-naphthyloxy-2-thiophenyl]-2-methylaminomethylcyclopropanes and their evaluation as inhibitors of serotonin, norepinephrine, and dopamine transporters. Journal of medicinal chemistry 20091008
A 52-year-old woman with disabling peripheral neuropathy: review of diabetic polyneuropathy. JAMA 20091007
Duloxetine for treating painful neuropathy or chronic pain. The Cochrane database of systematic reviews 20091007
In vitro inhibition and induction of human liver cytochrome p450 enzymes by milnacipran. Drug metabolism and disposition: the biological fate of chemicals 20091001
Evaluating the maintenance of effect of duloxetine in patients with diabetic peripheral neuropathic pain. Diabetes/metabolism research and reviews 20091001
Current progress in the pharmacological therapy of fibromyalgia. Expert opinion on investigational drugs 20091001
[Comparative efficacy and acceptability of new-generation antidepressants. Synthesis meta-analysis Cipriani]. L'Encephale 20091001
Recurrent episodes of serotonin-reuptake inhibitor-mediated hyponatremia in an elderly patient. The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20091001
Fibromyalgia and myofascial pain syndrome-a dilemma. Indian journal of anaesthesia 20091001
[Combination of dialectic and behavioral therapy (DBT) and duloxetin in kleptomania]. Psychiatrische Praxis 20090901
Duloxetine treatment for women with premenstrual dysphoric disorder: a single-blind trial. The international journal of neuropsychopharmacology 20090901
Cooperative opioid and serotonergic mechanisms generate superior antidepressant-like effects in a mice model of depression. The international journal of neuropsychopharmacology 20090901
A double-blind, randomized trial of duloxetine versus placebo in the management of chronic low back pain. European journal of neurology 20090901
Safety and tolerability of duloxetine in the treatment of patients with fibromyalgia: pooled analysis of data from five clinical trials. Clinical rheumatology 20090901
Successful pain relief of cutaneous leiomyomata due to reed syndrome with the combination treatment of pregabalin and duloxetine. Journal of pain and symptom management 20090901
N-[(3S)-Pyrrolidin-3-yl]benzamides as novel dual serotonin and noradrenaline reuptake inhibitors: impact of small structural modifications on P-gp recognition and CNS penetration. Bioorganic & medicinal chemistry letters 20090901
Sexual side-effects of contemporary antidepressants: review. The Australian and New Zealand journal of psychiatry 20090901
Duloxetine compliance and its association with healthcare costs among patients with diabetic peripheral neuropathic pain. Journal of medical economics 20090901
Medical management of stress urinary incontinence: is there a future? Current urology reports 20090901
Duloxetine serum concentrations and clinical effects. Data from a therapeutic drug monitoring (TDM) survey. Pharmacopsychiatry 20090901
Duloxetine hydro-chloride. Acta crystallographica. Section E, Structure reports online 20090901
Use of latency to immobility improves detection of antidepressant-like activity in the behavioral despair test in the mouse. European journal of pharmacology 20090815
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[Therapy for urinary incontinence in general practice]. Aktuelle Urologie 20090801
Duloxetine in obese binge eater outpatients: preliminary results from a 12-week open trial. Human psychopharmacology 20090801
Clinicians' views on the NICE guideline on the management of female urinary incontinence. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology 20090801
Fibromyalgia: poorly understood; treatments are disappointing. Prescrire international 20090801
The use of duloxetine in chronic bulimia nervosa: a case report. Psychiatry (Edgmont (Pa. : Township)) 20090801
Stress degradation studies on duloxetine hydrochloride and development of an RP-HPLC method for its determination in capsule formulation. Journal of chromatographic science 20090801
Rapid HPLC method for the simultaneous monitoring of duloxetine, venlaflaxine, fluoxetine and paroxetine in biofluids. Bioanalysis 20090801
Duloxetine-induced hypomania: case report and brief review of the literature on SNRIs-induced mood switching. Journal of psychopharmacology (Oxford, England) 20090701
Improvement with duloxetine in an adult ADHD patient. Journal of attention disorders 20090701
Duloxetine in the treatment of irritable bowel syndrome: an open-label pilot study. Human psychopharmacology 20090701
Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis. European journal of pharmacology 20090624
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A comparison of initial duloxetine dosing strategies in patients with major depressive disorder. The Journal of clinical psychiatry 20071201
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An independent meta-analysis using summary data for clinical response, remission, and discontinuation for any reason from the 6 pivotal phase III randomized clinical trials of duloxetine in major depressive disorder. Journal of clinical psychopharmacology 20070401
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