Home Other Building Blocks N-(4-Chloro-3-methoxyphenyl)pyridine-2-carboxamide

N-(4-Chloro-3-methoxyphenyl)pyridine-2-carboxamide

CAS No.:
1161205-04-4
Catalog Number:
AG000BOL
Molecular Formula:
C13H11ClN2O2
Molecular Weight:
262.6916
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
≥98%
1 week
United States
$91
- +
5mg
≥98%
1 week
United States
$135
- +
10mg
99%
1 week
United States
$173
- +
50mg
99%
1 week
United States
$457
- +
100mg
99%
1 week
United States
$707
- +
Product Description
Catalog Number:
AG000BOL
Chemical Name:
N-(4-Chloro-3-methoxyphenyl)pyridine-2-carboxamide
CAS Number:
1161205-04-4
Molecular Formula:
C13H11ClN2O2
Molecular Weight:
262.6916
MDL Number:
MFCD16618402
IUPAC Name:
N-(4-chloro-3-methoxyphenyl)pyridine-2-carboxamide
InChI:
InChI=1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17)
InChI Key:
ARYUXFNGXHNNDM-UHFFFAOYSA-N
SMILES:
COc1cc(ccc1Cl)NC(=O)c1ccccn1
Properties
Complexity:
288  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
262.051g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
262.693g/mol
Monoisotopic Mass:
262.051g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
51.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.6  
Literature
Title Journal
Functional and pharmacological characteristics of metabotropic glutamate receptors 2/4 heterodimers. Molecular pharmacology 20120901
Discovery, synthesis, and structure-activity relationship development of a series of N-4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): characterization of a novel positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)) with oral efficacy in an antiparkinsonian animal model. Journal of medicinal chemistry 20111110
Tricyclic thiazolopyrazole derivatives as metabotropic glutamate receptor 4 positive allosteric modulators. Journal of medicinal chemistry 20110728
Discovery, synthesis, and structure-activity relationship development of a series of N-(4-acetamido)phenylpicolinamides as positive allosteric modulators of metabotropic glutamate receptor 4 (mGlu(4)) with CNS exposure in rats. Journal of medicinal chemistry 20110224
Synthesis and evaluation of a series of heterobiarylamides that are centrally penetrant metabotropic glutamate receptor 4 (mGluR4) positive allosteric modulators (PAMs). Journal of medicinal chemistry 20090723
Properties