N-Methylnicotinamide
| Title | Journal |
|---|---|
| A small molecule inhibitor of mutant IDH2 rescues cardiomyopathy in a D-2-hydroxyglutaric aciduria type II mouse model. | Journal of inherited metabolic disease 20160101 |
| N-methylnicotinamide is an endogenous probe for evaluation of drug-drug interactions involving multidrug and toxin extrusions (MATE1 and MATE2-K). | Clinical pharmacology and therapeutics 20121101 |
| Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
| Nitric oxide production and endothelium-dependent vasorelaxation ameliorated by N1-methylnicotinamide in human blood vessels. | Hypertension (Dallas, Tex. : 1979) 20120401 |
| In vitro and in silico strategies to identify OATP1B1 inhibitors and predict clinical drug-drug interactions. | Pharmaceutical research 20120201 |
| Beneficial metabolic effects of 2',3',5'-tri-acetyl-N6- (3-hydroxylaniline) adenosine in the liver and plasma of hyperlipidemic hamsters. | PloS one 20120101 |
| Nicotinamide, NAD(P)(H), and Methyl-Group Homeostasis Evolved and Became a Determinant of Ageing Diseases: Hypotheses and Lessons from Pellagra. | Current gerontology and geriatrics research 20120101 |
| Characterization and crystallization of mouse aldehyde oxidase 3: from mouse liver to Escherichia coli heterologous protein expression. | Drug metabolism and disposition: the biological fate of chemicals 20111001 |
| Two different hydrogen bond donor ligands together: a selectivity improvement in organometallic {Re(CO)3} anion hosts. | Inorganic chemistry 20110905 |
| Characterization of organic anion-transporting polypeptide (Oatp) 1a1 and 1a4 null mice reveals altered transport function and urinary metabolomic profiles. | Toxicological sciences : an official journal of the Society of Toxicology 20110801 |
| Metabolomic assessment with CE-MS of the nutraceutical effect of Cystoseira spp extracts in an animal model. | Electrophoresis 20110801 |
| Identification of urinary biomarkers from X-irradiated mice using NMR spectroscopy. | Radiation research 20110501 |
| Fluorescence Spectrometric Determination of Drugs Containing α-Methylene Sulfone/Sulfonamide Functional Groups Using N-Methylnicotinamide Chloride as a Fluorogenic Agent. | International journal of analytical chemistry 20110101 |
| Nutritional and metabolic status of children with autism vs. neurotypical children, and the association with autism severity. | Nutrition & metabolism 20110101 |
| An insight into the metabolic responses of ultra-small superparamagnetic particles of iron oxide using metabonomic analysis of biofluids. | Nanotechnology 20101001 |
| A novel pathway for nicotine degradation by Aspergillus oryzae 112822 isolated from tobacco leaves. | Research in microbiology 20100901 |
| Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls. | Journal of proteome research 20100604 |
| Protective effect of nicotinamide against poly(ADP-ribose) polymerase-1-mediated astrocyte death depends on its transporter-mediated uptake. | Life sciences 20100424 |
| Diaqua-bis(5-bromo-2-hydroxy-benzoato)bis-(N-methyl-nicotinamide)zinc(II). | Acta crystallographica. Section E, Structure reports online 20100401 |
| Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption. | Analytical chemistry 20100215 |
| Identification of hypoxanthine as a urine marker for non-Hodgkin lymphoma by low-mass-ion profiling. | BMC cancer 20100101 |
| Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance. | Diabetology & metabolic syndrome 20100101 |
| A metabonomic comparison of urinary changes in Zucker and GK rats. | Journal of biomedicine & biotechnology 20100101 |
| Nicotinamide and its metabolite N-methylnicotinamide increase skin vascular permeability in rats. | Clinical and experimental dermatology 20090401 |
| Carrier-mediated uptake of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)-4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small-molecule survivin suppressant, into human solid tumor and lymphoma cells. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| Gastroduodenal mucosal defense. | Current gastroenterology reports 20081201 |
| Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
| Development of oxidative stress by cytochrome P450 induction in rodents is selective for barbiturates and related to loss of pyridine nucleotide-dependent protective systems. | The Journal of biological chemistry 20080620 |
| Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
| Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine. | The journal of nutrition, health & aging 20080401 |
| N-methylnicotinamide failed to induce endothelial prostacyclin release in perfused rat hindquarters. | Pharmacological reports : PR 20080101 |
| Effect of dronedarone on renal function in healthy subjects. | British journal of clinical pharmacology 20071201 |
| 1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells. | Toxicology in vitro : an international journal published in association with BIBRA 20071201 |
| Nitroso-imidacloprid irreversibly inhibits rabbit aldehyde oxidase. | Chemical research in toxicology 20071201 |
| Functional characterization of testis-specific rodent multidrug and toxic compound extrusion 2, a class III MATE-type polyspecific H+/organic cation exporter. | American journal of physiology. Cell physiology 20071101 |
| The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. | Biopharmaceutics & drug disposition 20070901 |
| N-methylnicotinamide inhibits arterial thrombosis in hypertensive rats. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20070901 |
| Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation. | International journal of clinical pharmacology and therapeutics 20070801 |
| Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites. | Journal of clinical pharmacology 20070601 |
| Niacin nutritional status in HIV type 1-positive children: preliminary data. | Journal of pediatric gastroenterology and nutrition 20070501 |
| A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human. | Physiological genomics 20070424 |
| Beyond lipids, pharmacological PPARalpha activation has important effects on amino acid metabolism as studied in the rat. | American journal of physiology. Endocrinology and metabolism 20070401 |
| Metabonomics evaluations of age-related changes in the urinary compositions of male Sprague Dawley rats and effects of data normalization methods on statistical and quantitative analysis. | BMC bioinformatics 20070101 |
| Changes in vitamin status of Indian Antarctic expeditioners during a one-month stay in Austral Summer. | Wilderness & environmental medicine 20070101 |
| 1H-NMR metabolic profiling of human neonatal urine. | Magma (New York, N.Y.) 20061201 |
| A metabonomics study of the hepatotoxicants galactosamine, methylene dianiline and clofibrate in rats. | Basic & clinical pharmacology & toxicology 20060901 |
| Characteristics of thiamine uptake by the BeWo human trophoblast cell line. | Journal of biochemistry and molecular biology 20060731 |
| Effect of standard nicotinamide in the prevention of type 1 diabetes in first degree relatives of persons with type 1 diabetes. | Autoimmunity 20060601 |
| Tetraethylammonium and nicotine transport by the Malpighian tubules of insects. | Journal of insect physiology 20060501 |
| Molecular tweezer and clip in aqueous solution: unexpected self-assembly, powerful host-guest complex formation, quantum chemical 1H NMR shift calculation. | Journal of the American Chemical Society 20060412 |
| The regulation and inhibition of 17beta-hydroxysteroid dehydrogenase in breast cancer. | Molecular and cellular endocrinology 20060327 |
| Evaluation of volatile ion-pair reagents for the liquid chromatography-mass spectrometry analysis of polar compounds and its application to the determination of methadone in human plasma. | Journal of pharmaceutical and biomedical analysis 20060224 |
| Liquid chromatographic/mass spectrometric procedure for measurement of NAD catabolites in human and rat plasma and urine. | Nucleosides, nucleotides & nucleic acids 20060101 |
| Electron transfer within complex II. Succinate:ubiquinone oxidoreductase of Escherichia coli. | The Journal of biological chemistry 20050930 |
| Molecular and functional characterization of an Na+-independent choline transporter in rat astrocytes. | Journal of neurochemistry 20050901 |
| Increased tubular organic ion clearance following chronic ACE inhibition in patients with type 1 diabetes. | Kidney international 20050601 |
| Tryptophan-NAD+ pathway metabolites as putative biomarkers and predictors of peroxisome proliferation. | Archives of toxicology 20050401 |
| Parkinson's disease: the first common neurological disease due to auto-intoxication? | QJM : monthly journal of the Association of Physicians 20050301 |
| Identification of aldehyde oxidase as the neonicotinoid nitroreductase. | Chemical research in toxicology 20050201 |
| Nicotinamide homeostasis: a xenobiotic pathway that is key to development and degenerative diseases. | Medical hypotheses 20050101 |
| [Pellagra]. | Sante (Montrouge, France) 20050101 |
| The effect of a series of organic cations upon the plasmalemmal serotonin transporter, SERT. | Life sciences 20041119 |
| The role of advanced glycation in reduced organic cation transport associated with experimental diabetes. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Niacin metabolite excretion in alcoholic pellagra and AIDS patients with and without diarrhea. | Nutrition (Burbank, Los Angeles County, Calif.) 20040901 |
| Effects of feeding and body weight loss on the 1H-NMR-based urine metabolic profiles of male Wistar Han rats: implications for biomarker discovery. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101 |
| Development of a multivariate statistical model to predict peroxisome proliferation in the rat, based on urinary 1H-NMR spectral patterns. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20040101 |
| Molecular tweezers and clips as synthetic receptors. Molecular recognition and dynamics in receptor-substrate complexes. | Accounts of chemical research 20031201 |
| Reduced tubular cation transport in diabetes: prevented by ACE inhibition. | Kidney international 20030601 |
| Influence of molecular structure on substrate binding to the human organic cation transporter, hOCT1. | Molecular pharmacology 20030301 |
| Evidence for a carrier-mediated mechanism for thiamine transport to human jejunal basolateral membrane vesicles. | Digestive diseases and sciences 20030101 |
| [Connection between changing the vitamin and immune status and the character of the throat microflora in patients with chronic tonsillitis]. | Otolaryngologia polska = The Polish otolaryngology 20030101 |
| Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101 |
| Cellular and molecular aspects of thiamin uptake by human liver cells: studies with cultured HepG2 cells. | Biochimica et biophysica acta 20021223 |
| Functional characterization of mouse cation transporter mOCT2 compared with mOCT1. | Biochemical and biophysical research communications 20020823 |
| Intramolecular electron transfer in cytochrome cd(1) nitrite reductase from Pseudomonas stutzeri; kinetics and thermodynamics. | Biophysical chemistry 20020710 |
| cDNA cloning, functional characterization, and tissue distribution of an alternatively spliced variant of organic cation transporter hOCT2 predominantly expressed in the human kidney. | Journal of the American Society of Nephrology : JASN 20020701 |
| Copper complexes with bioactive ligands. Part II--Antifungal activity. | Folia microbiologica 20020101 |
| Self-assembly of polymer and sheet structures from palladium(II) complexes by hydrogen bonding between carboxamide substituents. | Inorganic chemistry 20011119 |
| Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus. | The Journal of biological chemistry 20011109 |
| Mechanism of thiamine uptake by human jejunal brush-border membrane vesicles. | American journal of physiology. Cell physiology 20010901 |
| Interaction of cations, anions, and weak base quinine with rat renal cation transporter rOCT2 compared with rOCT1. | American journal of physiology. Renal physiology 20010901 |
| Intramolecular electron transfer from c heme to d1 heme in bacterial cytochrome cd1 nitrite reductase occurs over the same distances at very different rates depending on the source of the enzyme. | Biochemistry 20010724 |
| Effects of dietary pyrazinamide, an antituberculosis agent, on the metabolism of tryptophan to niacin and of tryptophan to serotonin in rats. | Bioscience, biotechnology, and biochemistry 20010601 |
| The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production. | The American journal of gastroenterology 20010401 |
| Cytosolic xanthine oxidoreductase mediated bioactivation of ethanol to acetaldehyde and free radicals in rat breast tissue. Its potential role in alcohol-promoted mammary cancer. | Toxicology 20010307 |
| Molecular and physiological evidence for multifunctionality of carnitine/organic cation transporter OCTN2. | Molecular pharmacology 20010201 |
| Hepatic uptake of synthetic chlorogenic acid derivatives by the organic anion transport proteins. | The Journal of pharmacology and experimental therapeutics 20010101 |
| Transport of [3H]MPP+ in an immortalized rat brain microvessel endothelial cell line (RBE 4). | Naunyn-Schmiedeberg's archives of pharmacology 20010101 |
| Rat ventral prostate xanthine oxidase bioactivation of ethanol to acetaldehyde and 1-hydroxyethyl free radicals: analysis of its potential role in heavy alcohol drinking tumor-promoting effects. | Teratogenesis, carcinogenesis, and mutagenesis 20010101 |
| Copper complexes with bioactive ligands Part I--Antimicrobial activity. | Folia microbiologica 20010101 |
| Functional characterization of an organic cation transporter (hOCT1) in a transiently transfected human cell line (HeLa). | The Journal of pharmacology and experimental therapeutics 19980701 |
| Cloning and characterization of two human polyspecific organic cation transporters. | DNA and cell biology 19970701 |
| Gentamicin nephrotoxicity. I. Degree and permanence of acquired insensitivity. | The Journal of laboratory and clinical medicine 19821001 |