Adipocyte-derived factors regulate vascular smooth muscle cells through mineralocorticoid and glucocorticoid receptors.

Hypertension (Dallas, Tex. : 1979) 20110901

Neuroendocrine contributions to sexual partner preference in birds.

Frontiers in neuroendocrinology 20110401

Intracerebral estrogen provision increases cytogenesis and neurogenesis in the injured zebra finch brain.

Developmental neurobiology 20110201

Distribution and sexually dimorphic expression of steroid receptor coactivator-1 (SRC-1) in the zebra finch brain.

General and comparative endocrinology 20110115

Species extrapolation for the 21st century.

Environmental toxicology and chemistry 20110101

Expression profiles of reproduction- and thyroid hormone-related transcripts in the brains of chemically-induced intersex frogs.

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 20110101

FAD286, an aldosterone synthase inhibitor, reduced atherosclerosis and inflammation in apolipoprotein E-deficient mice.

Journal of hypertension 20100901

Temporal expression and steroidal regulation of piRNA pathway genes (mael, piwi, vasa) during Silurana (Xenopus) tropicalis embryogenesis and early larval development.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20100801

Central neuronal activation and pressor responses induced by circulating ANG II: role of the brain aldosterone-'ouabain' pathway.

American journal of physiology. Heart and circulatory physiology 20100801

Sexual incentive motivation in male rats requires both androgens and estrogens.

Hormones and behavior 20100701

Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11beta-hydroxylase inhibitor metyrapone.

The Journal of pharmacology and experimental therapeutics 20100701

17beta-Estradiol levels in male zebra finch brain: combining Palkovits punch and an ultrasensitive radioimmunoassay.

General and comparative endocrinology 20100515

Fadrozole and finasteride exposures modulate sex steroid- and thyroid hormone-related gene expression in Silurana (Xenopus) tropicalis early larval development.

General and comparative endocrinology 20100401

Testosterone metabolites differentially maintain adult morphology in a sexually dimorphic neuromuscular system.

Developmental neurobiology 20100301

Sensitivity of New Zealand mudsnail Potamopyrgus antipodarum (Gray) to a specific aromatase inhibitor.

Chemosphere 20100301

Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2).

Journal of medicinal chemistry 20100225

Elevated plasma endoglin (CD105) predicts decreased response and survival in a metastatic breast cancer trial of hormone therapy.

Breast cancer research and treatment 20100201

Expression of estrogen receptor beta and phosphorylation of estrogen receptor alpha serine 167 correlate with progression-free survival in patients with metastatic breast cancer treated with aromatase inhibitors.

Oncology 20100101

Profiling neuroendocrine gene expression changes following fadrozole-induced estrogen decline in the female goldfish.

Physiological genomics 20090807

Altered gene expression in the brain and ovaries of zebrafish (Danio rerio) exposed to the aromatase inhibitor fadrozole: microarray analysis and hypothesis generation.

Environmental toxicology and chemistry 20090801

In situ hybridization to detect spatial gene expression in medaka.

Ecotoxicology and environmental safety 20090501

Short term treatment with aromatase inhibitor induces sex change in the protogynous wrasse, Halichoeres trimaculatus.

General and comparative endocrinology 20090501

Direct effects, compensation, and recovery in female fathead minnows exposed to a model aromatase inhibitor.

Environmental health perspectives 20090401

Recovery of motor and cognitive function after cerebellar lesions in a songbird: role of estrogens.

The European journal of neuroscience 20090301

Sex reversal of the amphibian, Xenopus tropicalis, following larval exposure to an aromatase inhibitor.

Aquatic toxicology (Amsterdam, Netherlands) 20090131

Estradiol induces sexual behavior in female túngara frogs.

Hormones and behavior 20090101

Masculinization of the European sea bass (Dicentrarchus labrax) by treatment with an androgen or aromatase inhibitor involves different gene expression and has distinct lasting effects on maturation.

General and comparative endocrinology 20090101

The aromatase inhibitor fadrozole and the 5-reductase inhibitor finasteride affect gonadal differentiation and gene expression in the frog Silurana tropicalis.

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 20090101

Time-dependent transcriptional profiles of genes of the hypothalamic-pituitary-gonadal axis in medaka (Oryzias latipes) exposed to fadrozole and 17beta-trenbolone.

Environmental toxicology and chemistry 20081201

Forebrain steroid levels fluctuate rapidly during social interactions.

Nature neuroscience 20081101

Aldosterone synthase inhibition improves cardiovascular function and structure in rats with heart failure: a comparison with spironolactone.

European heart journal 20080901

Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors.

Bioorganic & medicinal chemistry letters 20080815

Role of estrogen receptors and aromatase on brain protein synthesis rates in ovariectomized female rats fed genistein.

Nutritional neuroscience 20080801

Benzo(a)pyrene decreases brain and ovarian aromatase mRNA expression in Fundulus heteroclitus.

Aquatic toxicology (Amsterdam, Netherlands) 20080730

Ovarian P450 aromatase activity in the catfish Heteropneustes fossilis: seasonal changes and effects of catecholestrogens.

General and comparative endocrinology 20080501

DNA microarray application in ecotoxicology: experimental design, microarray scanning, and factors affecting transcriptional profiles in a small fish species.

Environmental toxicology and chemistry 20080301

DNA microarray-based ecotoxicological biomarker discovery in a small fish model species.

Environmental toxicology and chemistry 20080301

The adaptive significance of temperature-dependent sex determination in a reptile.

Nature 20080131

Sex determination: some like it hot (and some don't).

Nature 20080131

Fadrozole reverses cardiac fibrosis in spontaneously hypertensive heart failure rats: discordant enantioselectivity versus reduction of plasma aldosterone.

Endocrinology 20080101

Inhibition of injury-induced glial aromatase reveals a wave of secondary degeneration in the songbird brain.

Glia 20080101

Aromatase inhibitors: past, present and future in breast cancer therapy.

Medical oncology (Northwood, London, England) 20080101

Combined effects of DHEA and fadrozole on aggression and neural VIP immunoreactivity in the non-breeding male song sparrow.

Hormones and behavior 20080101

Transmission of relaxin and estrogens to suckling canine pups via milk and possible association with hip joint laxity.

American journal of veterinary research 20080101

Cloning and expression of R-Spondin1 in different vertebrates suggests a conserved role in ovarian development.

BMC developmental biology 20080101

Gonadal expression of Sf1 and aromatase during sex determination in the red-eared slider turtle (Trachemys scripta), a reptile with temperature-dependent sex determination.

Differentiation; research in biological diversity 20071201

Aromatase expression and cell proliferation following injury of the adult zebra finch hippocampus.

Developmental neurobiology 20071201

Estrogen mediation of injury-induced cell birth in neuroproliferative regions of the adult zebra finch brain.

Developmental neurobiology 20070701

Molecular cloning of doublesex and mab-3-related transcription factor 1, forkhead transcription factor gene 2, and two types of cytochrome P450 aromatase in Southern catfish and their possible roles in sex differentiation.

The Journal of endocrinology 20070701

Windows of embryonic sexual lability in two lizard species with environmental sex determination.

Ecology 20070701

Elevated plasma tissue inhibitor of metalloproteinase-1 level predicts decreased response and survival in metastatic breast cancer.

Cancer 20070515

Establishment of the need for oestrogen during implantation in non-human primates.

Reproductive biomedicine online 20070501

A graphical systems model to facilitate hypothesis-driven ecotoxicogenomics research on the teleost brain-pituitary-gonadal axis.

Environmental science & technology 20070101

Fugu (Takifugu rubripes) sexual differentiation: CYP19 regulation and aromatase inhibitor induced testicular development.

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 20070101

Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production.

Toxicology and applied pharmacology 20061115

Effects of aromatase inhibitors on in vitro steroidogenesis by Atlantic salmon (Salmo salar) gonadal and brain tissue.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20061001

Survival with aromatase inhibitors and inactivators versus standard hormonal therapy in advanced breast cancer: meta-analysis.

Journal of the National Cancer Institute 20060920

Individual differences in estrogen receptor alpha in select brain nuclei are associated with individual differences in aggression.

Hormones and behavior 20060801

Masculinization of female golden rabbitfish Siganus guttatus using an aromatase inhibitor treatment during sex differentiation.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060801

Lead optimization providing a series of flavone derivatives as potent nonsteroidal inhibitors of the cytochrome P450 aromatase enzyme.

Journal of medicinal chemistry 20060727

In vitro exposure of porcine prepubertal follicles to 4-chlorobiphenyl (PCB3) and its hydroxylated metabolites: effects on sex hormone levels and aromatase activity.

Toxicology letters 20060701

Inhibition of cytochrome p450 brain aromatase reduces two male specific sexual behaviours in the male Endler guppy (Poecilia reticulata).

General and comparative endocrinology 20060701

Evaluation of a commercial kit for measuring vitellogenin in the fathead minnow (Pimephales promelas).

Ecotoxicology and environmental safety 20060601

Can the dextroenantiomer of the aromatase inhibitor fadrozole be useful for clinical investigation of aldosterone-synthase inhibition?

Journal of hypertension 20060601

Investigation of aldosterone-synthase inhibition in rats.

Journal of hypertension 20060601

Relationship between brain and ovary aromatase activity and isoform-specific aromatase mRNA expression in the fathead minnow (Pimephales promelas).

Aquatic toxicology (Amsterdam, Netherlands) 20060310

Effects of estrogen in the male rat medial amygdala: infusion of an aromatase inhibitor lowers mating and bovine serum albumin-conjugated estradiol implants do not promote mating.

Neuroendocrinology 20060101

The effect of aromatase inhibitor, fadrozole, on sGnRHa stimulated LH secretion in goldfish (Carassius auratus) and common carp (Cyprinus carpio).

Reproductive biology 20060101

Three-dimensional model of cytochrome P450 human aromatase.

Journal of enzyme inhibition and medicinal chemistry 20051201

New aromatase inhibitors as second-line endocrine therapy in postmenopausal patients with metastatic breast carcinoma: a pooled analysis of the randomized trials.

Cancer 20051001

Extragonadal synthesis of estradiol is protective against kainic acid excitotoxic damage to the hippocampus.

Neuroreport 20050928

Estrogen provision by reactive glia decreases apoptosis in the zebra finch (Taeniopygia guttata).

Journal of neurobiology 20050801

The adrenocortical tumor cell line NCI-H295R as an in vitro screening system for the evaluation of CYP11B2 (aldosterone synthase) and CYP11B1 (steroid-11beta-hydroxylase) inhibitors.

The Journal of steroid biochemistry and molecular biology 20050801

Aromatase inhibition abolishes courtship behaviours in the ring dove (Streptopelia risoria) and reduces androgen and progesterone receptors in the hypothalamus and anterior pituitary gland.

Molecular and cellular biochemistry 20050801

Evidence that estrogen regulates the sex change of honeycomb grouper (Epinephelus merra), a protogynous hermaphrodite fish.

Journal of experimental zoology. Part A, Comparative experimental biology 20050601

Co-culture of primary human mammary fibroblasts and MCF-7 cells as an in vitro breast cancer model.

Toxicological sciences : an official journal of the Society of Toxicology 20050201

Effects of sex steroids and their inhibitors on endocrine parameters and gender growth differences in Eurasian perch (Perca fluviatilis) juveniles.

Steroids 20050201

Dehydroepiandrosterone regulates astroglia reaction to denervation of olfactory glomeruli.

Glia 20041115

Successful detection of (anti-)androgenic and aromatase inhibitors in pre-spawning adult fathead minnows (Pimephales promelas) using easily measured endpoints of sexual development.

Aquatic toxicology (Amsterdam, Netherlands) 20041018

Effects of estrogens during embryonal development on crowing in the domestic fowl.

Physiology & behavior 20040930

Combined effect of testosterone and apocynin on nitric oxide and superoxide production in PMA-differentiated THP-1 cells.

Biochimica et biophysica acta 20040917

Glial aromatization decreases neural injury in the zebra finch (Taeniopygia guttata): influence on apoptosis.

Journal of neuroendocrinology 20040801

Differential expression pattern and steroid hormone sensitivity of SNAP-25 and synaptoporin mRNA in the telencephalic song control nucleus HVC of the zebra finch.

The Journal of comparative neurology 20040712

Effects of follicle stimulating hormone on estradiol-17 beta production and P-450 aromatase (CYP19) activity and mRNA expression in brown trout vitellogenic ovarian follicles in vitro.

General and comparative endocrinology 20040601

Modulation by steroid hormones of a 'sexy' acoustic signal in an Oscine species, the Common Canary Serinus canaria.

Anais da Academia Brasileira de Ciencias 20040601

Aromatase modulation alters gonadal differentiation in developing zebrafish (Danio rerio).

Aquatic toxicology (Amsterdam, Netherlands) 20040414

Characterization of stable human aromatase expressed in E. coli.

Steroids 20040401

Expression of aromatase mRNA and effects of aromatase inhibitor during ovarian development in the medaka, Oryzias latipes.

Journal of experimental zoology. Part A, Comparative experimental biology 20040301

Sex inversion of sexually immature honeycomb grouper (Epinephelus merra) by aromatase inhibitor.

Zoological science 20040301

Presynaptic N-methyl-D-aspartate receptor expression is increased by estrogen in an aromatase-rich area of the songbird hippocampus.

The Journal of comparative neurology 20040216

Expression of androgen receptor mRNA in zebra finch song system: developmental regulation by estrogen.

The Journal of comparative neurology 20040216

The effects of the aromatase inhibitor fadrozole hydrochloride on fetuses and uteri in late pregnant rats.

The Journal of endocrinology 20040201

An aromatase inhibitor or high water temperature induce oocyte apoptosis and depletion of P450 aromatase activity in the gonads of genetic female zebrafish during sex-reversal.

Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20040101

Lack of efficacy of fadrozole in treating precocious puberty in girls with the McCune-Albright syndrome.

The Journal of clinical endocrinology and metabolism 20031201

Does alligator testis produce estradiol? A comparison of ovarian and testicular aromatase.

Biology of reproduction 20031001

Effect of non-steroidal aromatase inhibitor on blood plasma ovarian steroid and thyroid hormones in laying hen (Gallus domesticus).

Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20030901

Degree of sex reversal as related to plasma steroid levels in genetic female chickens (Gallus domesticus) treated with Fadrozole.

Molecular reproduction and development 20030801

Role of aromatization in anticipatory and consummatory aspects of sexual behavior in male rats.

Hormones and behavior 20030801

Estradiol in the male rat amygdala facilitates mounting but not ejaculation.

Physiology & behavior 20030701

Delayed implantation induced by fadrozole hydrochloride in rats.

Contraception 20030701

Endogenous estrogen formation is neuroprotective in model of cerebellar ataxia.

Endocrine 20030601

Estrogen regulates tyrosine hydroxylase expression in the neonate mouse midbrain.

Journal of neurobiology 20030301

Successful treatment of a symptomatic uterine leiomyoma in a perimenopausal woman with a nonsteroidal aromatase inhibitor.

Fertility and sterility 20030301

Aromatase inhibition affects testosterone-induced masculinization of song and the neural song system in female canaries.

Journal of neurobiology 20030205

DMRT1 is upregulated in the gonads during female-to-male sex reversal in ZW chicken embryos.

Biology of reproduction 20030201

Double-blind randomised trial comparing the non-steroidal aromatase inhibitors letrozole and fadrozole in postmenopausal women with advanced breast cancer.

Annals of oncology : official journal of the European Society for Medical Oncology 20030101

Induction of XY sex reversal by estrogen involves altered gene expression in a teleost, tilapia.

Cytogenetic and genome research 20030101

Inhibition of p-450 aromatase prevents feminisation and induces protection during cysticercosis.

International journal for parasitology 20021001

Effects of the aromatase inhibitor fadrozole on plasma sex steroid secretion, spermatogenesis and epididymis morphology in the lizard, Podarcis sicula.

Molecular reproduction and development 20020901

Relationship of serum HER-2/neu and serum CA 15-3 in patients with metastatic breast cancer.

Clinical chemistry 20020801

Morphological sex reversal upon short-term exposure to endocrine modulators in juvenile fathead minnow (Pimephales promelas).

Toxicology letters 20020510

Evaluation of the aromatase inhibitor fadrozole in a short-term reproduction assay with the fathead minnow (Pimephales promelas).

Toxicological sciences : an official journal of the Society of Toxicology 20020501

Testosterone promotes paternal behaviour in a monogamous mammal via conversion to oestrogen.

Proceedings. Biological sciences 20020422

Development of sexual partner preference in the zebra finch: a socially monogamous, pair-bonding animal.

Archives of sexual behavior 20020201

Sex reversal and aromatase in chicken.

The Journal of experimental zoology 20011201

[An elderly woman with breast cancer and multiple liver metastasis that responded well to combination therapy of fadrozole and tamoxifen].

Gan to kagaku ryoho. Cancer & chemotherapy 20011201

A summary of second-line randomized studies of aromatase inhibitors.

The Journal of steroid biochemistry and molecular biology 20011201

A comparative approach to structure-function studies of mammalian aromatases.

The Journal of steroid biochemistry and molecular biology 20011201

[Hepatic infusion of docetaxel using PEIT for a patient with stage IV breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20011101

Enantioselectivity of some 1-[(benzofuran-2-yl) phenylmethyl] imidazoles as aromatase (P450AROM) inhibitors.

Journal of enzyme inhibition 20011101

Estrogen stimulates brain-derived neurotrophic factor expression in embryonic mouse midbrain neurons through a membrane-mediated and calcium-dependent mechanism.

Journal of neuroscience research 20011015

Expression of AMH, SF1, and SOX9 in gonads of genetic female chickens during sex reversal induced by an aromatase inhibitor.

Developmental dynamics : an official publication of the American Association of Anatomists 20011001

Effect of the aromatase inhibitor CGS-16949A on pregnancy and secretion of progesterone, estradiol-17beta, prostaglandins E and F2alpha (PGE; PGF2alpha) and pregnancy specific protein B (PSPB) in 90-day ovariectomized pregnant ewes.

Prostaglandins & other lipid mediators 20010901

Advances in aromatase inhibition: clinical efficacy and tolerability in the treatment of breast cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research 20010901

Sex reversal in Nile tilapia (Oreochromis niloticus) using a nonsteroidal aromatase inhibitor.

The Journal of experimental zoology 20010701

[Endocrine therapy for advanced or recurrent breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20010701

Brain aromatase is neuroprotective.

Journal of neurobiology 20010615

Regulation of plasma gonadotropin II secretion by sex steroids, aromatase inhibitors, and antiestrogens in the protandrous black porgy, Acanthopagrus schlegeli Bleeker.

Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010601

Evaluation of the male pubertal onset assay to detect testosterone and steroid biosynthesis inhibitors in CD rats.

Toxicological sciences : an official journal of the Society of Toxicology 20010401

Aromatase inhibition reduces specifically one display of the ring dove courtship behavior.

General and comparative endocrinology 20010401

[Endometriosis and aromatase inhibitor].

Nihon rinsho. Japanese journal of clinical medicine 20010101

Intracellular aromatase and its relevance to the pharmacological efficacy of aromatase inhibitors.

The Journal of steroid biochemistry and molecular biology 20010101

Synergistic effect of CGS16949A and 5-fluorouracil on a human breast cancer cell line.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20010101

Inhibitory effect of a novel non-steroidal aromatase inhibitor, YM511 on the proliferation of MCF-7 human breast cancer cell.

The Journal of steroid biochemistry and molecular biology 19960501

A study of fadrozole, a new aromatase inhibitor, in postmenopausal women with advanced metastatic breast cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19920101

The effect of the aromatase inhibitor, rogletimide (pyridoglutethimide), on guinea pig adrenal cell steroidogenesis and placental microsomal aromatase activity: comparison with aminoglutethimide and CGS 16949A.

The Journal of steroid biochemistry and molecular biology 19911101

Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease.

Journal of medicinal chemistry 19910201

Highly selective inhibition of estrogen biosynthesis by CGS 20267, a new non-steroidal aromatase inhibitor.

The Journal of steroid biochemistry and molecular biology 19901220