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Home Other Building Blocks Tetrabenazine (+)-

Tetrabenazine (+)-

CAS No.:
1026016-83-0
Catalog Number:
AG0007VL
Molecular Formula:
C19H27NO3
Molecular Weight:
317.4226
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$140
- +
10mg
99%
1 week
United States
$173
- +
50mg
99%
1 week
United States
$307
- +
100mg
99%
1 week
United States
$457
- +
Product Description
Catalog Number:
AG0007VL
Chemical Name:
Tetrabenazine (+)-
CAS Number:
1026016-83-0
Molecular Formula:
C19H27NO3
Molecular Weight:
317.4226
MDL Number:
MFCD08461052
IUPAC Name:
(3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-1,3,4,6,7,11b-hexahydrobenzo[a]quinolizin-2-one
InChI:
InChI=1S/C19H27NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16H,5-7,10-11H2,1-4H3/t14-,16-/m1/s1
InChI Key:
MKJIEFSOBYUXJB-GDBMZVCRSA-N
SMILES:
COc1cc2c(cc1OC)CCN1[C@@H]2CC(=O)[C@@H](C1)CC(C)C
UNII:
69ENL3U6BF
Properties
Complexity:
425  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0
Exact Mass:
317.199g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
317.429g/mol
Monoisotopic Mass:
317.199g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
38.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.9  
Literature
Title Journal
Tetrabenazine for the treatment of chorea and other hyperkinetic movement disorders. Expert review of neurotherapeutics 20111101
Preparation and evaluation of tetrabenazine enantiomers and all eight stereoisomers of dihydrotetrabenazine as VMAT2 inhibitors. European journal of medicinal chemistry 20110501
Quadriparesis and dysarthria due to tetrabenazine therapy in a child with rheumatic chorea. Indian journal of pharmacology 20110101
Dantrolene is neuroprotective in Huntington's disease transgenic mouse model. Molecular neurodegeneration 20110101
Tetrabenazine, a monoamine-depleting drug used in the treatment of hyperkinetic movement disorders. The American journal of geriatric pharmacotherapy 20100801
Calcium signaling and neurodegeneration. Acta naturae 20100401
ELBARA II, an L-band radiometer system for soil moisture research. Sensors (Basel, Switzerland) 20100101
Tetrabenazine in the treatment of Huntington's disease. Neuropsychiatric disease and treatment 20071001
Properties