AM580
| Title | Journal |
|---|---|
| Quantitative high-throughput profiling of environmental chemicals and drugs that modulate farnesoid X receptor. | Scientific reports 20140101 |
| Roflumilast enhances the renal protective effects of retinoids in an HIV-1 transgenic mouse model of rapidly progressive renal failure. | Kidney international 20120501 |
| Can we cure HIV-1-associated nephropathy in transgenic mice? | Kidney international 20120501 |
| Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages. | Biochimica et biophysica acta 20120401 |
| Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1. | Proceedings of the National Academy of Sciences of the United States of America 20111108 |
| Effect of synthetic ligands of PPAR α, β/δ, γ, RAR, RXR and LXR on the fatty acid composition of phospholipids in mice. | Lipids 20111101 |
| Chemical genomics profiling of environmental chemical modulation of human nuclear receptors. | Environmental health perspectives 20110801 |
| Neuregulins are essential for spermatogonial proliferation and meiotic initiation in neonatal mouse testis. | Development (Cambridge, England) 20110801 |
| Retinoic acid inhibits endometrial cancer cell growth via multiple genomic mechanisms. | Journal of molecular endocrinology 20110401 |
| Role of the retinoic acid receptor-α in HIV-associated nephropathy. | Kidney international 20110301 |
| Identification of diaryl ether-based ligands for estrogen-related receptor α as potential antidiabetic agents. | Journal of medicinal chemistry 20110210 |
| Novel retinoic acid receptor alpha agonists for treatment of kidney disease. | PloS one 20110101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| Research resource: transcriptome profiling of genes regulated by RXR and its permissive and nonpermissive partners in differentiating monocyte-derived dendritic cells. | Molecular endocrinology (Baltimore, Md.) 20101101 |
| Retinoic acid receptor-α signalling antagonizes both intracellular and extracellular amyloid-β production and prevents neuronal cell death caused by amyloid-β. | The European journal of neuroscience 20101001 |
| Allele-specific down-regulation of RPTOR expression induced by retinoids contributes to climate adaptations. | PLoS genetics 20101001 |
| All-trans retinoic acid enhances the transport of phase II metabolites of benzo[a]pyrene by inducing the Breast Cancer Resistance Protein expression in Caco-2 cells. | Toxicology letters 20100816 |
| Keratins 2 and 4/13 in reconstituted human skin are reciprocally regulated by retinoids binding to nuclear receptor RARalpha. | Experimental dermatology 20100701 |
| Mechanism of inhibition of MMTV-neu and MMTV-wnt1 induced mammary oncogenesis by RARalpha agonist AM580. | Oncogene 20100624 |
| Acidic retinoids synergize with vitamin A to enhance retinol uptake and STRA6, LRAT, and CYP26B1 expression in neonatal lung. | Journal of lipid research 20100201 |
| Synthesis and pharmacological characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, silicon analogues of the RARalpha-selective retinoid agonists AM80 (Tamibarotene) and AM580. | ChemMedChem 20091101 |
| Design, synthesis, and structure-activity analysis of isoform-selective retinoic acid receptor beta ligands. | Journal of medicinal chemistry 20090326 |
| Novel non-carboxylic acid retinoids: 1,2,4-oxadiazol-5-one derivatives. | Bioorganic & medicinal chemistry letters 20090115 |
| Experimental effect of retinoic acids on apoptosis during the development of diabetic retinopathy. | Clinical ophthalmology (Auckland, N.Z.) 20080301 |
| Expression of retinoic acid receptors in human endometrial carcinoma. | Cancer science 20080201 |
| The Retinoic Acid Receptor-alpha mediates human T-cell activation and Th2 cytokine and chemokine production. | BMC immunology 20080101 |
| Galactomutarotase and other galactose-related genes are rapidly induced by retinoic acid in human myeloid cells. | Biochemistry 20071225 |
| Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. | Endocrinology 20071001 |
| A widely used retinoic acid receptor antagonist induces peroxisome proliferator-activated receptor-gamma activity. | Molecular pharmacology 20070501 |
| Inhibitory effects of retinoic acid receptor alpha stimulants on murine cataractogenesis through suppression of deregulated calpains. | Investigative ophthalmology & visual science 20070501 |
| Retinoic acid regulates CD1d gene expression at the transcriptional level in human and rodent monocytic cells. | Experimental biology and medicine (Maywood, N.J.) 20070401 |
| Cellular retinoic acid bioavailability determines epithelial integrity: Role of retinoic acid receptor alpha agonists in colitis. | Molecular pharmacology 20070101 |
| PPARgamma controls CD1d expression by turning on retinoic acid synthesis in developing human dendritic cells. | The Journal of experimental medicine 20061002 |
| Epigenetic silencing of occludin promotes tumorigenic and metastatic properties of cancer cells via modulations of unique sets of apoptosis-associated genes. | Cancer research 20060915 |
| Retinoic acid improves a hybridoma culture in a fructose-based medium by up-regulation of fructose incorporation via retinoid nuclear receptors. | Bioscience, biotechnology, and biochemistry 20060901 |
| Retinoic acid exerts dual regulatory actions on the expression and nuclear localization of interferon regulatory factor-1. | Experimental biology and medicine (Maywood, N.J.) 20060501 |
| Retinoic acid-induced CD38 expression in HL-60 myeloblastic leukemia cells regulates cell differentiation or viability depending on expression levels. | Journal of cellular biochemistry 20060415 |
| Retinoic acid induces p27Kip1 nuclear accumulation by modulating its phosphorylation. | Cancer research 20060415 |
| Telomerase targeting by retinoids in cells from patients with myeloid leukemias of various subtypes, not only APL. | Leukemia 20060401 |
| Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways. | Journal of cellular biochemistry 20060201 |
| Retinoic acid amplifies the host immune response to LPS through increased T lymphocytes number and LPS binding protein expression. | Molecular and cellular endocrinology 20051221 |
| Discovery of a potent, orally available, and isoform-selective retinoic acid beta2 receptor agonist. | Journal of medicinal chemistry 20051201 |
| Retinoic acid is a potential negative regulator for differentiation of human periodontal ligament cells. | Journal of periodontal research 20051201 |
| Physiological and receptor-selective retinoids modulate interferon gamma signaling by increasing the expression, nuclear localization, and functional activity of interferon regulatory factor-1. | The Journal of biological chemistry 20051028 |
| Trialkyltin compounds bind retinoid X receptor to alter human placental endocrine functions. | Molecular endocrinology (Baltimore, Md.) 20051001 |
| Expression of the retinoic acid-metabolizing enzyme CYP26A1 limits programmed cell death. | Molecular pharmacology 20050501 |
| Implication of Wt1 in the pathogenesis of nephrogenic failure in a mouse model of retinoic acid-induced caudal regression syndrome. | The American journal of pathology 20050501 |
| A retinoic acid receptor beta/gamma-selective prodrug (tazarotene) plus a retinoid X receptor ligand induces extracellular signal-regulated kinase activation, retinoblastoma hypophosphorylation, G0 arrest, and cell differentiation. | Molecular pharmacology 20041201 |
| Potentiation of the teratogenic effects induced by coadministration of retinoic acid or phytanic acid/phytol with synthetic retinoid receptor ligands. | Archives of toxicology 20041101 |
| Survival of activated human T lymphocytes is promoted by retinoic acid via induction of IL-2. | International immunology 20040301 |
| Modifying effects of 1'-acetoxychavicol acetate (ACA) and the novel synthetic retinoids Re-80, Am-580 and Am-55P in a two-stage carcinogenesis model in female rats. | Toxicologic pathology 20040101 |
| All-trans retinoic acid modulates microvascular endothelial cell hemostatic properties. | Haematologica 20030801 |
| Ligation of retinoic acid receptor alpha regulates negative selection of thymocytes by inhibiting both DNA binding of nur77 and synthesis of bim. | Journal of immunology (Baltimore, Md. : 1950) 20030401 |
| Arginine of retinoic acid receptor beta which coordinates with the carboxyl group of retinoic acid functions independent of the amino acid residues responsible for retinoic acid receptor subtype ligand specificity. | Archives of biochemistry and biophysics 20030115 |
| RAR agonists stimulate SOX9 gene expression in breast cancer cell lines: evidence for a role in retinoid-mediated growth inhibition. | Oncogene 20021107 |
| Synthesis and biological activity of retinoic acid receptor-alpha specific amides. | Bioorganic & medicinal chemistry letters 20021104 |
| Enhancement of the inducible NO synthase activation by retinoic acid is mimicked by RARalpha agonist in vivo. | American journal of physiology. Endocrinology and metabolism 20020901 |
| Effects of retinoic acid receptor-selective agonists on human nasal epithelial cell differentiation. | American journal of respiratory cell and molecular biology 20011201 |
| Phytanic acid and docosahexaenoic acid increase the metabolism of all-trans-retinoic acid and CYP26 gene expression in intestinal cells. | Biochimica et biophysica acta 20011031 |
| Retinoids inhibit the actions of angiotensin II on vascular smooth muscle cells. | Circulation research 20010330 |
| Synergistic teratogenic effects induced by retinoids in mice by coadministration of a RARalpha- or RARgamma-selective agonist with a RXR-selective agonist. | Toxicology and applied pharmacology 20010101 |
| Effects of retinoids on in vitro and in vivo IgE production. | International archives of allergy and immunology 20010101 |
| In silico discovery of novel retinoic acid receptor agonist structures. | BMC structural biology 20010101 |
| Induction of the cytochrome P450 gene CYP26 during mucous cell differentiation of normal human tracheobronchial epithelial cells. | Molecular pharmacology 20000901 |
| Retinoic acid is a negative regulator for the differentiation of cord blood-derived human mast cell progenitors. | Blood 20000501 |
| The role of specific retinoid receptors in sebocyte growth and differentiation in culture. | The Journal of investigative dermatology 20000201 |
| Evidence for the involvement of both retinoic acid receptor- and retinoic X receptor-dependent signaling pathways in the induction of tissue transglutaminase and apoptosis in the human myeloma cell line RPMI 8226. | Blood 19980401 |
| Selective high affinity retinoic acid receptor alpha or beta-gamma ligands. | Molecular pharmacology 19911001 |
| Retinobenzoic acids. 1. Structure-activity relationships of aromatic amides with retinoidal activity. | Journal of medicinal chemistry 19881101 |
| New benzoic acid derivatives with retinoid activity: lack of direct correlation between biological activity and binding to cellular retinoic acid binding protein. | Cancer research 19870701 |
| Purification and properties of polyol dehydrogenase from Cephalosporium chrysogenus. | Journal of bacteriology 19760101 |