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Phenylbiguanide

CAS No.:
102-02-3
Catalog Number:
AG00068B
Molecular Formula:
C8H11N5
Molecular Weight:
177.2064
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
98%
1 week
United States
$126
- +
10g
>98.0%(T)(HPLC)
1 week
United States
$494
- +
Product Description
Catalog Number:
AG00068B
Chemical Name:
Phenylbiguanide
CAS Number:
102-02-3
Molecular Formula:
C8H11N5
Molecular Weight:
177.2064
MDL Number:
MFCD01941521
IUPAC Name:
1-(diaminomethylidene)-2-phenylguanidine
InChI:
InChI=1S/C8H11N5/c9-7(10)13-8(11)12-6-4-2-1-3-5-6/h1-5H,(H6,9,10,11,12,13)
InChI Key:
CUQCMXFWIMOWRP-UHFFFAOYSA-N
SMILES:
N=C(Nc1ccccc1)NC(=N)N
EC Number:
202-998-5
UNII:
W8PKA3T2I3
Properties
Complexity:
211  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
177.101g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
177.211g/mol
Monoisotopic Mass:
177.101g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
103A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0
Literature
Title Journal
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The effects of catalase inhibition into the fourth cerebral ventricle on the Bezold-Jarisch reflex in spontaneously hypertensive rats. Journal of integrative neuroscience 20111201
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Roles of arterial baroreceptor reflex during bezold-jarisch reflex. Current cardiology reviews 20091101
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. Nature chemical biology 20091001
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5-HT inhibition of rat insulin 2 promoter Cre recombinase transgene and proopiomelanocortin neuron excitability in the mouse arcuate nucleus. Neuroscience 20090303
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5-HT-induced depression of the spinal monosynaptic reflex potential utilizes different types of 5-HT receptors depending on Mg2+ availability. Pharmacological reports : PR 20090101
Consequences of post-weaning social isolation on anxiety behavior and related neural circuits in rodents. Frontiers in behavioral neuroscience 20090101
Respiratory pattern in midline-lesioned brainstems and hemibrainstems from adult turtles. Respiratory physiology & neurobiology 20081231
Activation of cholecystokinin (CCK 1) and serotonin (5-HT 3) receptors increases the discharge of pancreatic vagal afferents. European journal of pharmacology 20081228
Cough reflex responses during pulmonary C-fibre receptor activation in anesthetized rabbits. Neuroscience letters 20081226
Excitability of small-diameter trigeminal ganglion neurons by 5-HT is mediated by enhancement of the tetrodotoxin-resistant sodium current due to the activation of 5-HT(4) receptors and/or by the inhibition of the transient potassium current. Neuroscience 20081202
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Cardiac vagal preganglionic neurones in the intermediate zone of the brainstem in anaesthetized cats. Experimental physiology 20071101
Nonuniformity in the von Bezold-Jarisch reflex. American journal of physiology. Regulatory, integrative and comparative physiology 20070801
Demonstration of 5-HT(3) receptor function and expression in the mouse bladder. Naunyn-Schmiedeberg's archives of pharmacology 20070801
5-HT2 and 5-HT3 receptors in the lateral parabrachial nucleus mediate opposite effects on sodium intake. Neuroscience 20070608
Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior. Neuroscience 20070511
The 1:1 cocrystals of the proton-transfer compound dilituric acid--phenylbiguanide monohydrate. Acta crystallographica. Section C, Crystal structure communications 20070301
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Vagal afferent input alters the discharge of osmotic and ANG II-responsive median preoptic neurons projecting to the hypothalamic paraventricular nucleus. Brain research 20070202
RVLM glycine receptors mediate GABAA and GABAB)independent sympathoinhibition from CVLM in rats. Brain research 20061213
Ptychodiscus brevis toxin-induced depression of spinal reflexes involves 5-HT via 5-HT3 receptors modulated by NMDA receptor. Neuroscience letters 20061127
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Ablation of NK1 receptor bearing neurons in the nucleus of the solitary tract blunts cardiovascular reflexes in awake rats. Brain research 20061113
The sympathoinhibitory effects of systemic cholecystokinin are dependent on neurons in the caudal ventrolateral medulla in the rat. American journal of physiology. Regulatory, integrative and comparative physiology 20061101
Tooth-pulp-evoked rostral spinal trigeminal neuronal excitation is attenuated by the activation of 5-HT3 receptors via GABAergic interneurons in the rat. Brain research 20060913
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Pancreatic vasoconstrictor responses are regulated by neurons in the rostral ventrolateral medulla. Brain research 20060802
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Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Characterisation of c-Fos expression in the central nervous system of mice following right atrial injections of the 5-HT3 receptor agonist phenylbiguanide. Autonomic neuroscience : basic & clinical 20051230
Blockade of 5-HT(3) receptor with MDL7222 and Y25130 reduces hydrogen peroxide-induced neurotoxicity in cultured rat cortical cells. Life sciences 20051205
Medullary lateral tegmental field mediates the cardiovascular but not respiratory component of the Bezold-Jarisch reflex in the cat. American journal of physiology. Regulatory, integrative and comparative physiology 20051201
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Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat. Clinical and experimental pharmacology & physiology 20051001
Blockade of 5-HT(3) receptor with MDL 72222 and Y 25130 reduces beta-amyloid protein (25--35)-induced neurotoxicity in cultured rat cortical neurons. European journal of pharmacology 20050927
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A functional study of uncrossed and crossed pulmonary afferent fibres in the cervical vagus nerves of the cat. Autonomic neuroscience : basic & clinical 20010620
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ANP, BNP, and CNP enhance bradycardic responses to cardiopulmonary chemoreceptor activation in conscious sheep. American journal of physiology. Regulatory, integrative and comparative physiology 20010101
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The effect of ketanserin on cardiovascular reflexes in conscious normotensive and spontaneously hypertensive rats. European journal of pharmacology 19900904
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