3-Pyridinecarboxamide, 1,6-dihydro-N-methyl-6-oxo-
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N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity. | Journal of physiology and biochemistry 20120901 |
Simultaneous quantification of niacin and its three main metabolites in human plasma by LC-MS/MS. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120901 |
Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line. | Acta biochimica Polonica 20110101 |
Simultaneous determination of niacin and its metabolites--nicotinamide, nicotinuric acid and N-methyl-2-pyridone-5-carboxamide--in human plasma by LC-MS/MS and its application to a human pharmacokinetic study. | Biomedical chromatography : BMC 20101001 |
Distribution of purine nucleotides in uremic fluids and tissues. | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20100901 |
Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls. | Journal of proteome research 20100604 |
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry. | Molecular bioSystems 20100501 |
Development of a hydrophilic liquid interaction chromatography-high-performance liquid chromatography-tandem mass spectrometry based stable isotope dilution analysis and pharmacokinetic studies on bioactive pyridines in human plasma and urine after coffee consumption. | Analytical chemistry 20100215 |
Are so-called uremic toxins always toxic? | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101 |
Nicotinamide metabolites accumulate in the tissues of uremic rats. | Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20080101 |
The comparative bioavailability of an extended-release niacin and lovastatin fixed dose combination tablet versus extended-release niacin tablet, lovastatin tablet and a combination of extended-release niacin tablet and lovastatin tablet. | Biopharmaceutics & drug disposition 20070901 |
Plasma and urine pharmacokinetics of niacin and its metabolites from an extended-release niacin formulation. | International journal of clinical pharmacology and therapeutics 20070801 |
Effect of the rate of niacin administration on the plasma and urine pharmacokinetics of niacin and its metabolites. | Journal of clinical pharmacology 20070601 |
A metabolomic comparison of urinary changes in type 2 diabetes in mouse, rat, and human. | Physiological genomics 20070424 |
Relationship between uremic toxins and oxidative stress in patients with chronic renal failure. | Scandinavian journal of urology and nephrology 20070101 |
Accumulation of poly(ADP-ribose) polymerase inhibitors in children with chronic renal failure. | Pediatric nephrology (Berlin, Germany) 20060601 |
Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats. | Drug metabolism and disposition: the biological fate of chemicals 20060201 |
The novel nucleotide 4KNTP, in high concentrations in erythrocytes of renal failure children: a comparison with accumulation of other putative precursors in the plasma. | Nucleosides, nucleotides & nucleic acids 20060101 |
The effect of N-methyl-2-pyridone-5-carboxamide--A nicotinamide catabolite on poly ADP-rybosylation and oxidative stress injury in endothelial cells. | Nucleosides, nucleotides & nucleic acids 20050101 |
The age-related increase in N-methyl-2-pyridone-5-carboxamide (NAD catabolite) in human plasma. | Molecular and cellular biochemistry 20041201 |
An unusual pyridine nucleotide accumulating in erythrocytes: its identity and positive correlation with degree of renal failure. | Nucleosides, nucleotides & nucleic acids 20041001 |
Disturbances of purine nucleotide metabolism in uremia. | Seminars in nephrology 20040901 |
Origin and characteristics of an unusual pyridine nucleotide accumulating in erythrocytes: positive correlation with degree of renal failure. | Clinica chimica acta; international journal of clinical chemistry 20030901 |
N-methyl-2-pyridone-5-carboxamide: a novel uremic toxin? | Kidney international. Supplement 20030501 |
Accumulation of plasma N-methyl-2-pyridone-5-carboxamide in patients with chronic renal failure. | Molecular and cellular biochemistry 20020201 |
The metabolism of nicotinamide in human liver cirrhosis: a study on N-methylnicotinamide and 2-pyridone-5-carboxamide production. | The American journal of gastroenterology 20010401 |