13-chloro-2-(piperidin-4-ylidene)-4-azatricyclo[9.4.0.0^{3,8}]pentadeca-1(11),3(8),4,6,12,14-hexaene
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Desloratadine improves quality of life and symptom severity in patients with allergic rhinitis. | Allergy 20071101 |
Validated ion pair liquid chromatography/fluorescence detection method for assessing the variability of the loratadine metabolism occurring in bioequivalence studies. | Biomedical chromatography : BMC 20071001 |
Response normalized liquid chromatography nanospray ionization mass spectrometry. | Journal of the American Society for Mass Spectrometry 20071001 |
Multiple-dose pharmacokinetics and safety of desloratadine in subjects with moderate hepatic impairment. | Journal of clinical pharmacology 20071001 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20070901 |
Desloratadine treatment for intermittent and persistent allergic rhinitis: a review. | Clinical therapeutics 20070901 |
Desloratadine dose selection in children aged 6 months to 2 years: comparison of population pharmacokinetics between children and adults. | British journal of clinical pharmacology 20070801 |
Determination of loratadine and its active metabolite in human plasma by high-performance liquid chromatography with mass spectrometry detection. | Journal of pharmaceutical and biomedical analysis 20070727 |
Disposition of loratadine in healthy volunteers. | Xenobiotica; the fate of foreign compounds in biological systems 20070701 |
Disposition of desloratadine in healthy volunteers. | Xenobiotica; the fate of foreign compounds in biological systems 20070701 |
The effect of regular versus on-demand desloratadine treatment in children with allergic rhinitis. | International journal of pediatric otorhinolaryngology 20070601 |
Pharmacokinetics of desloratadine in children between 2 and 11 years of age. | British journal of clinical pharmacology 20070501 |
Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet (20 mg) versus desloratadine capsule (5 mg): a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adults. | Clinical therapeutics 20070501 |
Influence of food on the oral bioavailability of rupatadine tablets in healthy volunteers: a single-dose, randomized, open-label, two-way crossover study. | Clinical therapeutics 20070501 |
The nose - from symptoms to evidence-based medicine. | Allergy 20070401 |
Efficacy of desloratadine in the treatment of allergic rhinitis: a meta-analysis of randomized, double-blind, controlled trials. | Allergy 20070401 |
Simultaneous determination of loratadine and desloratadine in pharmaceutical preparations using liquid chromatography with a microemulsion as eluent. | Journal of pharmaceutical and biomedical analysis 20070312 |
Quantitative determination of amantadine in human plasma by liquid chromatography-mass spectrometry and the application in a bioequivalence study. | Journal of pharmaceutical and biomedical analysis 20070312 |
Selective inhibition of Kir currents by antihistamines. | European journal of pharmacology 20070308 |
Effectiveness of desloratadine 5 mg once daily in patients with symptoms of seasonal allergic rhinitis: results of a Canadian multicenter, open-label trial. | Clinical therapeutics 20070301 |
Efficacy of Bacillus clausii spores in the prevention of recurrent respiratory infections in children: a pilot study. | Therapeutics and clinical risk management 20070301 |
Effects of desloratadine and alcohol coadministration on psychomotor performance. | Current medical research and opinion 20070201 |
The effect of 4 weeks treatment with desloratadine (5mg daily) on levels of interleukin (IL)-4, IL-10, IL-18 and TGF beta in patients suffering from seasonal allergic rhinitis. | Pulmonary pharmacology & therapeutics 20070101 |
Efficacy and safety of desloratadine in adults with chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled, multicenter trial. | American journal of clinical dermatology 20070101 |
Efficacy of fexofenadine versus desloratadine in suppressing histamine-induced wheal and flare. | Allergy and asthma proceedings 20070101 |
A sensitive spectrophotometric method for the determination of desloratadine in tablets. | Journal of AOAC International 20070101 |
Direct injection liquid chromatographic technique for simultaneous determination of two antihistaminic drugs and their main metabolites in serum. | Journal of AOAC International 20070101 |
Premedication with montelukast reduces local reactions of allergen immunotherapy. | International archives of allergy and immunology 20070101 |
A comparison of ebastine 10 mg fast-dissolving tablet with oral desloratadine and placebo in inhibiting the cutaneous reaction to histamine in healthy adults. | Clinical drug investigation 20070101 |
Simultaneous determination of desloratadine and pseudoephedrine in human plasma using micro solid-phase extraction tips and aqueous normal-phase liquid chromatography/tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20070101 |
Diphenhydramine versus nonsedating antihistamines for acute allergic reactions: a literature review. | Allergy and asthma proceedings 20070101 |
Desloratadine for chronic idiopathic urticaria: a review of clinical efficacy. | American journal of clinical dermatology 20070101 |
Eosinophil recruiting chemokines are down-regulated in peripheral blood mononuclear cells of allergic patients treated with deflazacort or desloratadine. | International journal of immunopathology and pharmacology 20070101 |
[Antihistamines in allergic rhinitis]. | Otolaryngologia polska = The Polish otolaryngology 20070101 |
Verapamil, but not probenecid, co-administration can convert desloratadine to a sedating antihistamine in mice. | Drug metabolism letters 20070101 |
Desloratadine in combination with montelukast suppresses the dermographometer challenge test papule, and is effective in the treatment of delayed pressure urticaria: a randomized, double-blind, placebo-controlled study. | The British journal of dermatology 20061201 |
Long QT syndrome in a patient with allergic rhinoconjunctivitis and auto-immune diabetes: focus on the choice of anti-H1 drugs. | European annals of allergy and clinical immunology 20061201 |
New antihistamines: a critical view. | Jornal de pediatria 20061101 |
Montelukast with desloratadine or levocetirizine for the treatment of persistent allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20061101 |
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101 |
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20061101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060901 |
Bacillus aerius sp. nov., Bacillus aerophilus sp. nov., Bacillus stratosphericus sp. nov. and Bacillus altitudinis sp. nov., isolated from cryogenic tubes used for collecting air samples from high altitudes. | International journal of systematic and evolutionary microbiology 20060701 |
Diphenhydramine vs desloratadine comparisons must consider risk-benefit ratio. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060701 |
Combining desloratadine and pseudoephedrine in the treatment of seasonal allergic rhinitis. | Expert review of clinical immunology 20060701 |
Form I of desloratadine, a tricyclic antihistamine. | Acta crystallographica. Section C, Crystal structure communications 20060601 |
The relative bioavailability of loratadine administered as a chewing gum formulation in healthy volunteers. | European journal of clinical pharmacology 20060601 |
Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis. | Southern medical journal 20060601 |
Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060601 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060601 |
A comparison of levocetirizine and desloratadine in the histamine-induced wheal and flare response in human skin in vivo. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060601 |
Antimuscarinic actions of antihistamines on the heart. | Journal of biomedical science 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060501 |
Influence of desloratadine on oxidative stress markers in patients with chronic idiopathic urticaria. | International journal of dermatology 20060401 |
Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060401 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060401 |
Adult and paediatric poor metabolisers of desloratadine: an assessment of pharmacokinetics and safety. | Expert opinion on drug safety 20060301 |
Desloratadine 5 mg once daily improves the quality of life of patients with chronic idiopathic urticaria. | Journal of the European Academy of Dermatology and Venereology : JEADV 20060301 |
Evaluation of product switching after a state Medicaid program began covering loratadine OTC 1 year after market availability. | Journal of managed care pharmacy : JMCP 20060301 |
Desloratadine therapy for symptoms associated with perennial allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060301 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060301 |
Desloratadine for allergic rhinitis. | Expert review of clinical immunology 20060301 |
Orthogonal extraction/chromatography and UPLC, two powerful new techniques for bioanalytical quantitation of desloratadine and 3-hydroxydesloratadine at 25 pg/mL. | Journal of pharmaceutical and biomedical analysis 20060224 |
Effect of desloratadine therapy on symptom scores and measures of nasal patency in seasonal allergic rhinitis: results of a single-center, placebo-controlled trial. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060201 |
Changes in pH differently affect the binding properties of histamine H1 receptor antagonists. | European journal of pharmacology 20060120 |
Effect of desloratadine on epithelial cell granulocyte-macrophage colony-stimulating factor secretion and eosinophil survival. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20060101 |
Azelastine nasal spray and desloratadine tablets in pollen-induced seasonal allergic rhinitis: a pharmacodynamic study of onset of action and efficacy. | Current medical research and opinion 20060101 |
A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitis. | Clinical therapeutics 20060101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20060101 |
The role of antihistamines in asthma management. | Treatments in respiratory medicine 20060101 |
Levocetirizine: a review of its use in the management of allergic rhinitis and skin allergies. | Drugs 20060101 |
Impact of desloratadine and loratadine on the crosstalk between human keratinocytes and leukocytes: Implications for anti-inflammatory activity of antihistamines. | International archives of allergy and immunology 20060101 |
Stimulating effects of H1-antagonists. | Current pharmaceutical design 20060101 |
Efficacy of desloratadine, 5 mg, compared with fexofenadine, 180 mg, in patients with symptomatic seasonal allergic rhinitis. | Allergy and asthma proceedings 20060101 |
Comparison of the risk of drowsiness and sedation between levocetirizine and desloratadine: a prescription-event monitoring study in England. | Drug safety 20060101 |
Effect of desloratadine on the control of morning symptoms in patients with seasonal and perennial allergic rhinitis. | Allergy and asthma proceedings 20060101 |
Selecting the optimal oral antihistamine for patients with allergic rhinitis. | Drugs 20060101 |
A comparative study on the cost of new antibiotics and drugs of other therapeutic categories. | PloS one 20060101 |
Relationship between human leucocyte antigen class I and class II and chronic idiopathic urticaria associated with aspirin and/or NSAIDs hypersensitivity. | Mediators of inflammation 20060101 |
Desloratadine and levocetirizine improve nasal symptoms, airflow, and allergic inflammation in patients with perennial allergic rhinitis: a pilot study. | International immunopharmacology 20051201 |
Treatment for allergic rhinitis and chronic idiopathic urticaria: focus on oral antihistamines. | The Annals of pharmacotherapy 20051201 |
Sexual dysfunction in patients with allergic rhinoconjunctivitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20051201 |
Management of persistent allergic rhinitis: evidence-based treatment with levocetirizine. | Therapeutics and clinical risk management 20051201 |
The effect of desloratadine on eosinophil/basophil progenitors and other inflammatory markers in seasonal allergic rhinitis: a placebo-controlled randomized study. | International archives of allergy and immunology 20051101 |
Review of desloratadine for the treatment of allergic rhinitis, chronic idiopathic urticaria and allergic inflammatory disorders. | Expert opinion on pharmacotherapy 20051101 |
[Isotachophoretic determination of desloratadine in tablets and syrup]. | Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20051101 |
Desloratadine reduces systemic allergic inflammation following nasal provocation in allergic rhinitis and asthma patients. | Allergy 20051001 |
Effect of combined montelukast and desloratadine on the early asthmatic response to inhaled allergen. | The Journal of allergy and clinical immunology 20051001 |
Acute bacterial rhinosinusitis causes hyperresponsiveness to histamine challenge in mice. | Archives of otolaryngology--head & neck surgery 20051001 |
Effect of cyp2d6*10 allele on the pharmacokinetics of loratadine in chinese subjects. | Drug metabolism and disposition: the biological fate of chemicals 20050901 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20050901 |
Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050901 |
Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines. | Journal of the American Academy of Nurse Practitioners 20050801 |
[Desloratadine for chronic idiopathic urticaria]. | Harefuah 20050801 |
Review of H1 antihistamines in the treatment of chronic idiopathic urticaria. | Cutis 20050801 |
A treatment for allergic rhinitis: a view on the role of levocetirizine. | Current medical research and opinion 20050701 |
[Study on determination of desloratadine in human serum and its pharmacokinetics by HPLC/MS]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20050701 |
A review of the evidence from comparative studies of levocetirizine and desloratadine for the symptoms of allergic rhinitis. | Clinical therapeutics 20050701 |
Acute cholestasis related to desloratidine. | World journal of gastroenterology 20050621 |
Determination of desloratadine in drug substance and pharmaceutical preparations by liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20050615 |
Histamine-mediated mechanisms in the human nasal airway. | Current opinion in pharmacology 20050601 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20050601 |
[The effect of desloratadine on the TXB2 and leukotrienes levels in the nasal lavage fluid of allergic rhinitis animal model]. | Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20050401 |
Evidence of desloratadine syrup efficacy and tolerability in children with pollen-induced allergic rhinitis. | Allergy 20050301 |
Co-administration of ketoconazole with H1-antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects. | British journal of clinical pharmacology 20050301 |
Increased nasal airflow with budesonide compared with desloratadine during the allergy season. | Archives of otolaryngology--head & neck surgery 20050301 |
Efficacy and safety of an extended-release formulation of desloratadine and pseudoephedrine vs the individual components in the treatment of seasonal allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050301 |
[The immunohistochemical observations of NOS in the nasal mucosa of allergic rhinitis animal model of guinea pigs]. | Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20050301 |
Metabolism and excretion of loratadine in male and female mice, rats and monkeys. | Xenobiotica; the fate of foreign compounds in biological systems 20050201 |
[Effects of budesonide, desloratadine and dexamethasone on interleukine-4 release and expression from human mast cell line]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20050201 |
[The effect of desloratadine on use of rescue beta2-agonists and symptoms in patients suffering from seasonal allergic rhinitis and asthma]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050201 |
[The influence of desloratadine on course of intermittens allergic rhinitis]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20050201 |
Inhibition of nasal polyp mast cell and eosinophil activation by desloratadine. | Allergy 20050101 |
Desloratadine prevents compound 48/80-induced mast cell degranulation: visualization using a vital fluorescent dye technique. | Allergy 20050101 |
Efficacy and tolerability of newer antihistamines in the treatment of allergic conjunctivitis. | Drugs 20050101 |
Effects of first and second generation antihistamines on muscarinic induced mucus gland cell ion transport. | BMC pharmacology 20050101 |
Pharmacological management of allergic rhinitis in the elderly: safety issues with oral antihistamines. | Drugs & aging 20050101 |
[Preliminary clinical study of fubiding in treatment of perennial allergic rhinitis]. | Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology 20050101 |
Fetal safety of drugs used in the treatment of allergic rhinitis: a critical review. | Drug safety 20050101 |
In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine. | BMC pharmacology 20050101 |
[Therapeutic options in idiopathic chronic urticaria]. | Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20050101 |
The safety and efficacy of desloratadine for the management of allergic disease. | Drug safety 20050101 |
Efficacy and safety of desloratadine/pseudoephedrine tablet, 2.5/120 mg two times a day, versus individual components in the treatment of patients with seasonal allergic rhinitis. | Allergy and asthma proceedings 20050101 |
Predicting and establishing the clinical efficacy of a histamine h(1)-receptor antagonist : desloratadine, the model paradigm. | Clinical drug investigation 20050101 |
Desloratadine inhibits constitutive and histamine-stimulated nuclear factor-kappaB activity consistent with inverse agonism at the histamine H1 Receptor. | International archives of allergy and immunology 20041201 |
Inhibitory effects of budesonide, desloratadine and dexamethasone on cytokine release from human mast cell line (HMC-1). | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20041201 |
Safety of desloratadine syrup in children. | Current medical research and opinion 20041201 |
Cetirizine and loratadine-based antihistamines with 5-lipoxygenase inhibitory activity. | Bioorganic & medicinal chemistry letters 20041115 |
Pharmacokinetics/pharmacodynamics of desloratadine and fluoxetine in healthy volunteers. | Journal of clinical pharmacology 20041101 |
Homology modelling and binding site mapping of the human histamine H1 receptor. | European journal of medicinal chemistry 20041101 |
Comparative pharmacology of guinea pig cardiac myocyte and cloned hERG (I(Kr)) channel. | Journal of cardiovascular electrophysiology 20041101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20041101 |
Current concepts and therapeutic strategies for allergic rhinitis in school-age children. | Clinical therapeutics 20041101 |
Comparison of the effects in the nose and skin of a single dose of desloratadine and levocetirizine over 24 hours. | International archives of allergy and immunology 20041001 |
Desloratadine partially inhibits the augmented bacterial responses in the sinuses of allergic and infected mice. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20041001 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20041001 |
Identification of human UDP-glucuronosyltransferase enzyme(s) responsible for the glucuronidation of 3-hydroxydesloratadine. | Biopharmaceutics & drug disposition 20040901 |
Anti-inflammatory properties of desloratadine. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901 |
Desloratadine in combination with montelukast in the treatment of chronic urticaria: a randomized, double-blind, placebo-controlled study. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040901 |
Randomized placebo-controlled trial comparing desloratadine and montelukast in monotherapy and desloratadine plus montelukast in combined therapy for chronic idiopathic urticaria. | The Journal of allergy and clinical immunology 20040901 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20040901 |
Modern histamine H1-receptor antagonists in the unified airway. | The Journal of allergy and clinical immunology 20040901 |
Antihistamines: do they work? Further well-controlled trials involving larger samples are needed. | Allergy 20040801 |
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans. | Fundamental & clinical pharmacology 20040801 |
[Nasal obstruction on the decline. Antihistamine allows allergic patients to breathe]. | MMW Fortschritte der Medizin 20040708 |
Effects of desloratadine, diphenhydramine, and placebo on driving performance and psychomotor performance measurements. | European journal of clinical pharmacology 20040701 |
Oral administration of desloratadine prior to sensitization prevents allergen-induced airway inflammation and hyper-reactivity in mice. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040701 |
Levocetirizine improves nasal obstruction and modulates cytokine pattern in patients with seasonal allergic rhinitis: a pilot study. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040601 |
Comparative activity of cetirizine and desloratadine on histamine-induced wheal-and-flare responses during 24 hours. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20040601 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20040601 |
[Combination therapy of allergic rhinitis. So that from hay fever asthma won't come]. | MMW Fortschritte der Medizin 20040527 |
Influx and efflux transport of H1-antagonist epinastine across the blood-brain barrier. | Drug metabolism and disposition: the biological fate of chemicals 20040501 |
Desloratadine shows no effect on performance during 6 h at 8,000 ft simulated cabin altitude. | Aviation, space, and environmental medicine 20040501 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20040501 |
[Not a minor illness. Hay fever therapy should not be left to the patient]. | MMW Fortschritte der Medizin 20040408 |
Improvements in simulated real-world relevant performance for patients with seasonal allergic rhinitis: impact of desloratadine. | Allergy 20040401 |
Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20040401 |
Levocetirizine better protects than desloratadine in a nasal provocation with allergen. | The Journal of allergy and clinical immunology 20040401 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20040401 |
High-performance liquid chromatographic method for the bioequivalence evaluation of desloratadine fumarate tablets in dogs. | Journal of pharmaceutical and biomedical analysis 20040310 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20040301 |
Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine. | Managed care interface 20040201 |
Comparative clinical efficacy, onset and duration of action of levocetirizine and desloratadine for symptoms of seasonal allergic rhinitis in subjects evaluated in the Environmental Exposure Unit (EEU). | International journal of clinical practice 20040201 |
Antihistamines added to an antileukotriene in treating seasonal allergic rhinitis: histamine and leukotriene antagonism. | European annals of allergy and clinical immunology 20040201 |
Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research. | Current medical research and opinion 20040101 |
Inhibition of cold urticaria by desloratadine. | The Journal of dermatological treatment 20040101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20040101 |
Evaluation of the utilization patterns of leukotriene modifiers in a large managed care health plan. | Journal of managed care pharmacy : JMCP 20040101 |
Pharmacokinetics and bioequivalence study of a generic desloratadine tablet formulation in healthy male volunteers. | Arzneimittel-Forschung 20040101 |
Onset of action for the relief of allergic rhinitis symptoms with second-generation antihistamines. | Allergy and asthma proceedings 20040101 |
The ARIA/EAACI criteria for antihistamines: an assessment of the efficacy, safety and pharmacology of desloratadine. | Allergy 20040101 |
Reported case of severe hepatotoxicity likely due to fluconazole and not desloratadine. | Acta haematologica 20040101 |
Chronic urticaria: aetiology, management and current and future treatment options. | Drugs 20040101 |
Direct injection of 96-well organic extracts onto a hydrophilic interaction chromatography/tandem mass spectrometry system using a silica stationary phase and an aqueous/organic mobile phase. | Rapid communications in mass spectrometry : RCM 20040101 |
[Autoimmune urticaria. Treatment with methotrexate]. | Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20040101 |
Interactions of olopatadine and selected antihistamines with model and natural membranes. | Ocular immunology and inflammation 20031201 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20031201 |
Desloratadine for allergic rhinitis. | American family physician 20031115 |
[Modern antihistaminics against allergic rhinitis. Better breathing without side effects]. | MMW Fortschritte der Medizin 20031030 |
Reliable and specific high-performance liquid chromatographic method for simultaneous determination of loratadine and its metabolite in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031025 |
Twenty-four-hour activity and consistency of activity of levocetirizine and desloratadine in the skin. | British journal of clinical pharmacology 20031001 |
Comparison of the effects of desloratadine and levocetirizine on histamine-induced wheal, flare and itch in human skin. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20031001 |
Efficacy and safety profile of fexofenadine HCl: a unique therapeutic option in H1-receptor antagonist treatment. | The Journal of allergy and clinical immunology 20031001 |
A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031001 |
Loratadine, desloratadine and pregnancy: don't use, risk of hypospadias. | Prescrire international 20031001 |
Studies on performance and sleepiness with the H1-antihistamine, desloratadine. | Aviation, space, and environmental medicine 20030801 |
Efficacy of azelastine nasal spray in patients with an unsatisfactory response to loratadine. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030801 |
Pharmacokinetic properties of single-dose loratadine and ambroxol alone and combined in tablet formulations in healthy men. | Clinical therapeutics 20030801 |
Validation of a sensitive and automated 96-well solid-phase extraction liquid chromatography-tandem mass spectrometry method for the determination of desloratadine and 3-hydroxydesloratadine in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030725 |
Desloratadine inhibits allergen-induced airway inflammation and bronchial hyperresponsiveness and alters T-cell responses in murine models of asthma. | The Journal of allergy and clinical immunology 20030701 |
Pharmacokinetics of loratadine and its active metabolite descarboethoxyloratadine in healthy Chinese subjects. | Acta pharmacologica Sinica 20030701 |
Comparison of ketotifen fumarate ophthalmic solution alone, desloratadine alone, and their combination for inhibition of the signs and symptoms of seasonal allergic rhinoconjunctivitis in the conjunctival allergen challenge model: a double-masked, placebo- and active-controlled trial. | Clinical therapeutics 20030701 |
Comparison of the effects of desloratadine 5-mg daily and placebo on nasal airflow and seasonal allergic rhinitis symptoms induced by grass pollen exposure. | Allergy 20030601 |
Effects of mediator antagonism on mannitol and adenosine monophosphate challenges. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030601 |
The effects of histamine and leukotriene receptor antagonism on nasal mannitol challenge in allergic rhinitis. | British journal of clinical pharmacology 20030601 |
[Clinical aspects of anti-inflammatory action of antihistamines]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030601 |
[Safety of new antihistamines]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030601 |
[Multicenter study of the effectiveness and tolerability of desloratadine in seasonal allergic rhinitis]. | Orvosi hetilap 20030525 |
First do no harm: managing antihistamine impairment in patients with allergic rhinitis. | The Journal of allergy and clinical immunology 20030501 |
Efficacy and safety of desloratadine 5 mg once daily in the treatment of chronic idiopathic urticaria: a double-blind, randomized, placebo-controlled trial. | Journal of the American Academy of Dermatology 20030401 |
Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma. | International archives of allergy and immunology 20030401 |
[Older antihistaminics often act as sedatives. Hay fever gone -- reaction capacity, too]. | MMW Fortschritte der Medizin 20030327 |
P-glycoprotein limits the brain penetration of nonsedating but not sedating H1-antagonists. | Drug metabolism and disposition: the biological fate of chemicals 20030301 |
Efficacy and safety of desloratadine in the treatment of perennial allergic rhinitis. | The Journal of allergy and clinical immunology 20030301 |
Decongestant effects of antihistamines: a class effect? | The Journal of allergy and clinical immunology 20030301 |
Double-stranded RNA viruses in a mycocinogenic strain of Cystofilobasidium infirmominiatum. | FEMS yeast research 20030301 |
Gateways to clinical trials. March 2003. | Methods and findings in experimental and clinical pharmacology 20030301 |
Desloratadine: a nonsedating antihistamine. | The Annals of pharmacotherapy 20030201 |
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma. | The Journal of allergy and clinical immunology 20030201 |
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Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine. | BMC family practice 20030101 |
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Severe hepatotoxicity after application of desloratadine and fluconazole. | Acta haematologica 20030101 |
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Safety and efficacy of desloratadine 5 mg in asthma patients with seasonal allergic rhinitis and nasal congestion. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021101 |
Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021001 |
Desloratadine reduces allergen challenge-induced mucinous secretion and plasma exudation in allergic rhinitis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021001 |
Desloratidine for the treatment of chronic urticaria. | Skin therapy letter 20021001 |
Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor. | European journal of pharmacology 20020809 |
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Effect of desloratadine versus placebo on nasal airflow and subjective measures of nasal obstruction in subjects with grass pollen-induced allergic rhinitis in an allergen-exposure unit. | The Journal of allergy and clinical immunology 20020601 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020501 |
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Synthesis of 5,6-dihydro-11H-benzo[5,6]-cyclohepta[1,2-b]pyridin-11-ylidene)-1-piperidine-N-cyanoguanidine derivatives as inhibitors of ras farnesyl protein transferase. | Bioorganic & medicinal chemistry letters 20020225 |
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Desloratadine demonstrates dose proportionality in healthy adults after single doses. | Clinical pharmacokinetics 20020101 |
Oral bioavailability of desloratadine is unaffected by food. | Clinical pharmacokinetics 20020101 |
A pharmacokinetic profile of desloratadine in healthy adults, including elderly. | Clinical pharmacokinetics 20020101 |
Effect of race and sex on single and multiple dose pharmacokinetics of desloratadine. | Clinical pharmacokinetics 20020101 |
Lack of clinically relevant interaction between desloratadine and erythromycin. | Clinical pharmacokinetics 20020101 |
Desloratadine has no clinically relevant electrocardiographic or pharmacodynamic interactions with ketoconazole. | Clinical pharmacokinetics 20020101 |
Investigation of an enhanced resolution triple quadrupole mass spectrometer for high-throughput liquid chromatography/tandem mass spectrometry assays. | Rapid communications in mass spectrometry : RCM 20020101 |
Efficacy of once-daily desloratadine/pseudoephedrine for relief of nasal congestion. | Allergy and asthma proceedings 20020101 |
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Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestion. | American journal of respiratory medicine : drugs, devices, and other interventions 20020101 |
Second-generation antihistamines in asthma therapy: is there a protective effect? | American journal of respiratory medicine : drugs, devices, and other interventions 20020101 |
Desloratadine reduces nasal congestion in patients with intermittent allergic rhinitis. | Allergy 20011101 |
In vitro characterization of the inhibition profile of loratadine, desloratadine, and 3-OH-desloratadine for five human cytochrome P-450 enzymes. | Drug metabolism and disposition: the biological fate of chemicals 20010901 |
Inhibition of cytokine generation and mediator release by human basophils treated with desloratadine. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010901 |
Applications of new liquid chromatography-tandem mass spectrometry technologies for drug development support. | Journal of chromatography. A 20010810 |
Evaluation of the interaction of loratadine and desloratadine with P-glycoprotein. | Drug metabolism and disposition: the biological fate of chemicals 20010801 |
Effect of desloratadine and loratadine on rhinovirus-induced intercellular adhesion molecule 1 upregulation and promoter activation in respiratory epithelial cells. | The Journal of allergy and clinical immunology 20010801 |
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Sensitive liquid chromatography-tandem mass spectrometry method for the determination of loratadine and its major active metabolite descarboethoxyloratadine in human plasma. | Journal of chromatography. A 20010420 |
Evaluation of a four-channel multiplexed electrospray triple quadrupole mass spectrometer for the simultaneous validation of LC/MS/MS methods in four different preclinical matrixes. | Analytical chemistry 20010415 |
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Desloratadine: A new, nonsedating, oral antihistamine. | The Journal of allergy and clinical immunology 20010401 |
Loratadine and terfenadine interaction with nefazodone: Both antihistamines are associated with QTc prolongation. | Clinical pharmacology and therapeutics 20010301 |
Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study. | Clinical therapeutics 20010301 |
Pharmacology and clinical efficacy of desloratadine as an anti-allergic and anti-inflammatory drug. | Expert opinion on investigational drugs 20010301 |
Decongestant efficacy of desloratadine in patients with seasonal allergic rhinitis. | Allergy 20010101 |
Desloratadine activity in concurrent seasonal allergic rhinitis and asthma. | Allergy 20010101 |
Desloratadine in the treatment of chronic idiopathic urticaria. | Allergy 20010101 |
Desloratadine: a new approach in the treatment of allergy as a systematic disease--pharmacology and clinical overview. Introduction. | Allergy 20010101 |
The pharmacologic profile of desloratadine: a review. | Allergy 20010101 |
Once-daily desloratadine improves the signs and symptoms of chronic idiopathic urticaria: a randomized, double-blind, placebo-controlled study. | International journal of dermatology 20010101 |
Desloratadine. | Drugs 20010101 |
[The effect of second generation histamine antagonists on the heart]. | Pneumonologia i alergologia polska 20010101 |
Chronic idiopathic urticaria treatment. | Allergologia et immunopathologia 20010101 |
Mediator antagonists in the treatment of allergic disease. | Allergy and asthma proceedings 20010101 |
Sedation with 'non-sedating' antihistamines: four prescription-event monitoring studies in general practice. | BMJ (Clinical research ed.) 20000429 |