3-Carbamyl-1-methylpyridinium chloride
Title | Journal |
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N-Methyl-2-pyridone-5-carboxamide is 1-methylnicotinamide metabolite of low cyclooxygenase-dependent vasodilating activity. | Journal of physiology and biochemistry 20120901 |
Toxic effects of nicotinamide methylation on mouse brain striatum neuronal cells and its relation to manganese. | Environmental health and preventive medicine 20120901 |
Excess nicotinamide inhibits methylation-mediated degradation of catecholamines in normotensives and hypertensives. | Hypertension research : official journal of the Japanese Society of Hypertension 20120201 |
Effects of N1-methylnicotinamide on oxidative and glycooxidative stress markers in rats with streptozotocin-induced diabetes mellitus. | Redox report : communications in free radical research 20120101 |
Developmental changes of aldehyde oxidase activity and protein expression in human liver cytosol. | Drug metabolism and pharmacokinetics 20120101 |
Decreased skin-mediated detoxification contributes to oxidative stress and insulin resistance. | Experimental diabetes research 20120101 |
The expression of nicotinamide N-methyltransferase increases ATP synthesis and protects SH-SY5Y neuroblastoma cells against the toxicity of Complex I inhibitors. | The Biochemical journal 20110515 |
¹H nuclear magnetic resonance based metabolic urinary profiling of patients with ischemic heart failure. | Clinical biochemistry 20110301 |
Effect of tea beverages on aldehyde oxidase activity. | Drug metabolism and pharmacokinetics 20110101 |
Effects of 1-methylnicotinamide and its metabolite N-methyl-2-pyridone-5-carboxamide on streptozotocin-induced toxicity in murine insulinoma MIN6 cell line. | Acta biochimica Polonica 20110101 |
Effect of selected NAD+ analogues on mitochondria activity and proliferation of endothelial EA.hy926 cells. | European journal of pharmacology 20100825 |
1-methylnicotinamide effects on the selected markers of endothelial function, inflammation and haemostasis in diabetic rats. | European journal of pharmacology 20100825 |
3-D-QSAR and docking studies on the neuronal choline transporter. | Bioorganic & medicinal chemistry letters 20100815 |
[Effect of 1-methylnicotinamide on prooxidant-antioxidant balance parameters in rats during hepatic ischemia-reperfusion]. | Eksperimental'naia i klinicheskaia farmakologiia 20100401 |
1-methylnicotinamide (MNA) in prevention of diabetes-associated brain disorders. | Neurochemistry international 20100101 |
Nicotinamide N-methyltransferase (NNMT) and 1-methylnicotinamide (MNA) in experimental hepatitis induced by concanavalin A in the mouse. | Pharmacological reports : PR 20100101 |
Effect of nicotinamide and its two derivatives on the generation of reactive oxygen species in human monocytes cooperating with platelets. | Acta poloniae pharmaceutica 20100101 |
Nicotinamide overload may play a role in the development of type 2 diabetes. | World journal of gastroenterology 20091207 |
Adipose tissue as a source of nicotinamide N-methyltransferase and homocysteine. | Atherosclerosis 20090601 |
Activation of nicotinamide N-methyltrasferase and increased formation of 1-methylnicotinamide (MNA) in atherosclerosis. | Pharmacological reports : PR 20090101 |
Anti-diabetic effects of 1-methylnicotinamide (MNA) in streptozocin-induced diabetes in rats. | Pharmacological reports : PR 20090101 |
Matrix metaloproteinases activity during the evolution of hypoxic-ischemic brain damage in the immature rat. The effect of 1-methylnicotinamide (MNA). | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080901 |
Aldehyde oxidase-catalyzed metabolism of N1-methylnicotinamide in vivo and in vitro in chimeric mice with humanized liver. | Drug metabolism and disposition: the biological fate of chemicals 20080701 |
Therapeutic potential of 1-methylnicotinamide against acute gastric lesions induced by stress: role of endogenous prostacyclin and sensory nerves. | The Journal of pharmacology and experimental therapeutics 20080701 |
1-Methylnicotinamide and nicotinamide: two related anti-inflammatory agents that differentially affect the functions of activated macrophages. | Archivum immunologiae et therapiae experimentalis 20080401 |
Anti-inflammatory effect of 1-methylnicotinamide in contact hypersensitivity to oxazolone in mice; involvement of prostacyclin. | European journal of pharmacology 20080114 |
1-Methylnicotinamide (MNA) prevents endothelial dysfunction in hypertriglyceridemic and diabetic rats. | Pharmacological reports : PR 20080101 |
Neuroprotective effects of nicotinamide and 1-methylnicotinamide in acute excitotoxicity in vitro. | Folia neuropathologica 20080101 |
Nicotinamide and 1-methylnicotinamide reduce homocysteine neurotoxicity in primary cultures of rat cerebellar granule cells. | Acta neurobiologiae experimentalis 20080101 |
1-Methylnicotinamide stimulates cell growth and inhibits hemoglobin synthesis in differentiating murine erythroleukemia cells. | Toxicology in vitro : an international journal published in association with BIBRA 20071201 |
1-Methylnicotinamide (MNA), a primary metabolite of nicotinamide, exerts anti-thrombotic activity mediated by a cyclooxygenase-2/prostacyclin pathway. | British journal of pharmacology 20070901 |
Developmental changes of aldehyde oxidase in postnatal rat liver. | Drug metabolism and pharmacokinetics 20070401 |
Metabolites of the radiosensitizer nicotinamide are unlikely to contribute to the degree of emesis observed with the parent drug. | Oncology research 20070101 |
Spectrofluorimetric determination of drugs containing active methylene group using N1-methyl nicotinamide chloride as a fluorigenic agent. | Chemical & pharmaceutical bulletin 20060701 |
Estimation of aldehyde oxidase activity in vivo from conversion ratio of N1-methylnicotinamide to pyridones, and intraspecies variation of the enzyme activity in rats. | Drug metabolism and disposition: the biological fate of chemicals 20060201 |
Search for drugs of the combined anti-inflammatory and anti-bacterial properties: 1-methyl-N'-(hydroxymethyl)nicotinamide. | Pharmacological reports : PR 20060101 |
[The effect of magnesium pool isotopy on reactivation of mitochondrial ATP synthesis suppressed by 1-methyl-nicotine amide]. | Biomeditsinskaia khimiia 20060101 |
Topical application of 1-methylnicotinamide in the treatment of rosacea: a pilot study. | Clinical and experimental dermatology 20051101 |
Quantitation of the niacin metabolites 1-methylnicotinamide and l-methyl-2-pyridone-5-carboxamide in random spot urine samples, by ion-pairing reverse-phase HPLC with UV detection, and the implications for the use of spot urine samples in the assessment of niacin status. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050325 |
Spectrofluorimetric determination of warfarin sodium by using N1-methylnicotinamide chloride as a fluorigenic agent. | Journal of AOAC International 20050101 |
1-Methylnicotinamide: a potent anti-inflammatory agent of vitamin origin. | Polish journal of pharmacology 20030101 |
Potential urinary and plasma biomarkers of peroxisome proliferation in the rat: identification of N-methylnicotinamide and N-methyl-4-pyridone-3-carboxamide by 1H nuclear magnetic resonance and high performance liquid chromatography. | Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20030101 |
[Elucidation of paraquat poisoning mechanism and development of the neuronal death model]. | Nihon eiseigaku zasshi. Japanese journal of hygiene 20020401 |
Possible role of 1-methylnicotinamide in the pathogenesis of Parkinson's disease. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20020201 |
Rapid calmodulin-dependent interdomain electron transfer in neuronal nitric-oxide synthase measured by pulse radiolysis. | The Journal of biological chemistry 20011026 |
Validation of an HPLC method for the determination of urinary and plasma levels of N1-methylnicotinamide, an endogenous marker of renal cationic transport and plasma flow. | Journal of pharmaceutical and biomedical analysis 20010101 |