Home Other Building Blocks Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-bis(hydrogen sulfate), sodium salt (1:2)

Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-bis(hydrogen sulfate), sodium salt (1:2)

CAS No.:
10040-45-6
Catalog Number:
AG0001XS
Molecular Formula:
C18H13NNa2O8S2
Molecular Weight:
481.4073
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
98%(HPLC)
In Stock USA
United States
$72
- +
100mg
98%(HPLC)
In Stock USA
United States
$125
- +
250mg
98%(HPLC)
In Stock USA
United States
$226
- +
1g
98%(HPLC)
In Stock USA
United States
$618
- +
5g
98%(HPLC)
In Stock USA
United States
$1821
- +
Product Description
Catalog Number:
AG0001XS
Chemical Name:
Phenol, 4,4'-(2-pyridinylmethylene)bis-, 1,1'-bis(hydrogen sulfate), sodium salt (1:2)
CAS Number:
10040-45-6
Molecular Formula:
C18H13NNa2O8S2
Molecular Weight:
481.4073
MDL Number:
MFCD28009648
IUPAC Name:
disodium;[4-[pyridin-2-yl-(4-sulfonatooxyphenyl)methyl]phenyl] sulfate
InChI:
InChI=1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2
InChI Key:
GOZDTZWAMGHLDY-UHFFFAOYSA-L
SMILES:
[O-]S(=O)(=O)Oc1ccc(cc1)C(c1ccccn1)c1ccc(cc1)OS(=O)(=O)[O-].[Na+].[Na+]
EC Number:
233-120-9
UNII:
VW106606Y8
Properties
Complexity:
633  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
480.988g/mol
Formal Charge:
0
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
481.401g/mol
Monoisotopic Mass:
480.988g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
163A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Comparison of patient acceptance of sodium phosphate versus polyethylene glycol plus sodium picosulfate for colon cleansing in Japanese. Journal of gastroenterology and hepatology 20121001
A pilot study on the efficacy of Picolax given as a four-week course for the treatment of refractory constipation. Hong Kong medical journal = Xianggang yi xue za zhi 20121001
Laxative-free CT colonography. The British journal of radiology 20120801
Serial monitoring of the physiological effects of the standard Pico-Salax® regimen for colon cleansing in healthy volunteers. Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20120701
Split-dose picosulfate, magnesium oxide, and citric acid solution markedly enhances colon cleansing before colonoscopy: a randomized, controlled trial. Gastrointestinal endoscopy 20120301
Laxative management in ambulatory cancer patients on opioid therapy: a prospective, open-label investigation of polyethylene glycol, sodium picosulphate and lactulose. European journal of cancer care 20120101
Same-day bowel cleansing regimen is superior to a split-dose regimen over 2 days for afternoon colonoscopy: results from a large prospective series. Journal of clinical gastroenterology 20120101
Same day prep for afternoon colonoscopy: everybody wins! Journal of clinical gastroenterology 20120101
Budget-impact model for colonoscopy cost calculation and comparison between 2 litre PEG+ASC and sodium picosulphate with magnesium citrate or sodium phosphate oral bowel cleansing agents. Journal of medical economics 20120101
Drug eruption due to sodium picosulfate. European journal of dermatology : EJD 20120101
Service implications of implementing guidance for oral bowel cleansing agents in colonoscopy. The journal of the Royal College of Physicians of Edinburgh 20110601
Bowel cleansing for colonoscopy: prospective randomized assessment of efficacy and of induced mucosal abnormality with three preparation agents. Endoscopy 20110501
Absence of excretion of the active moiety of bisacodyl and sodium picosulfate into human breast milk: an open-label, parallel-group, multiple-dose study in healthy lactating women. Drug metabolism and pharmacokinetics 20110101
Bowel preparation regimen for computed tomography colonography. Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes 20101201
Evidence-based recommendations for bowel cleansing before colonoscopy in children: a report from a national working group. Endoscopy 20101201
Multicenter, 4-week, double-blind, randomized, placebo-controlled trial of sodium picosulfate in patients with chronic constipation. The American journal of gastroenterology 20100401
A possible troponin I leak arising from bowel preparation for elective colonoscopy - are there more implications than observed? Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20100301
Pico-Salax versus polyethylene glycol for bowel cleanout before colonoscopy in children: a randomized controlled trial. Endoscopy 20091201
A multicentre, observational study of sodium picosulfate and magnesium citrate as a precolonoscopy bowel preparation. Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20091001
[Preparation of colonoscopy: well tolerable combination preparation admitted in Germany]. MMW Fortschritte der Medizin 20090924
Plasma magnesium should be monitored perioperatively in patients undergoing colorectal resection. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20090701
The rapid development of hyponatraemia and seizures in an elderly patient following sodium picosulfate/magnesium citrate (Picolax). Age and ageing 20090701
Pico-salax plus two-day bisacodyl is superior to pico-salax alone or oral sodium phosphate for colon cleansing before colonoscopy. The American journal of gastroenterology 20090301
Sodium picosulfate/magnesium citrate: a review of its use as a colorectal cleanser. Drugs 20090101
[Optimization of perioperative management in laparoscopic hernioplasty]. Der Anaesthesist 20080901
A randomized controlled trial comparing the efficacy and acceptability of phospo-soda buffered saline (Fleet) with sodium picosulphate/magnesium citrate (Picoprep) in the preparation of patients for colonoscopy. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20080601
A randomised controlled trial of a new 2 litre polyethylene glycol solution versus sodium picosulphate + magnesium citrate solution for bowel cleansing prior to colonoscopy. Current medical research and opinion 20080201
OTC laxative use of sodium picosulfate â results of a pharmacy-based patient survey (cohort study). International journal of clinical pharmacology and therapeutics 20080201
[Treatment with bisacodyl, picosulfate and prokinetics. Physiopathology and diagnosis of constipation]. Pharmazie in unserer Zeit 20080101
Factors affecting outcomes in colonoscopy. Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20080101
Comparison of colon-cleansing methods in preparation for colonoscopy--comparative efficacy of solutions of mannitol, sodium picosulfate and monobasic and dibasic sodium phosphates. Acta cirurgica brasileira 20080101
Commonly used bowel preparations have significant and different effects upon cell proliferation in the colon: a pilot study. BMC gastroenterology 20080101
Interaction between Shaoyao-Gancao-Tang and a laxative with respect to alteration of paeoniflorin metabolism by intestinal bacteria in rats. Phytomedicine : international journal of phytotherapy and phytopharmacology 20070801
Is patient outcome affected by the administration of intravenous fluid during bowel preparation for colonic surgery? Annals of the Royal College of Surgeons of England 20070701
Randomised, placebo-controlled, double-blind study to investigate the efficacy and safety of the acute use of sodium picosulphate in patients with chronic constipation. International journal of clinical practice 20070601
Comparison of bisacodyl and sodium picosulphate in the treatment of chronic constipation. Current medical research and opinion 20070401
A review of current issues underlying colon cleansing before colonoscopy. Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20070201
Randomized clinical trial comparing sodium picosulfate with mannitol on the preparation FOR colonoscopy in hospitalized patients. Arquivos de gastroenterologia 20070101
[Preparation for colonoscopy using 1,000 ml Magcorol P isotonic solution in the absence of dietary restrictions or use of purgatives on the preceding day]. Revista de gastroenterologia del Peru : organo oficial de la Sociedad de Gastroenterologia del Peru 20070101
Sodium picosulfate in opioid-induced constipation: results of an open-label, prospective, dose-ranging study. Palliative medicine 20060601
Which is the optimal bowel preparation for colonoscopy - a meta-analysis. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20060501
Audit of bowel preparation with Picolax (sodium picosulfate plus magnesium citrate) for colonoscopy. International journal of clinical practice 20060501
An unusual difficulty in bowel preparation for emergency colonoscopy. Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20060101
Bioavailability of glycyrrhizin from Shaoyao-Gancao-Tang in laxative-treated rats. The Journal of pharmacy and pharmacology 20051001
Effects of oral sodium picosulphate Picolax on urea and electrolytes. Nursing standard (Royal College of Nursing (Great Britain) : 1987) 20050701
Screening procedure for detection of stimulant laxatives and/or their metabolites in human urine using gas chromatography-mass spectrometry after enzymatic cleavage of conjugates and extractive methylation. Therapeutic drug monitoring 20050401
Randomized single blind trial of two low-volume bowel preparations for screening computed tomographic colonography. Abdominal imaging 20050101
Psychological well-being and symptoms in women with chronic constipation treated with sodium picosulphate. Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 20050101
Retrospective study of long-term treatment with sodium picosulfate. European journal of gastroenterology & hepatology 20040401
Picoprep-3 is a superior colonoscopy preparation to Fleet: a randomized, controlled trial comparing the two bowel preparations. Diseases of the colon and rectum 20040201
[Bowel preparation for colonoscopy with sodium picosulphate and magnesium citrate in children and adolescents]. Arquivos de gastroenterologia 20040101
Optimizing bowel preparation for multidetector row CT colonography: effect of Citramag and Picolax. Clinical radiology 20030901
[Comparison of the effectiveness and tolerability of the saccharosum-sennosid-B solution and sodium-picosulfate in preparation for colonoscopy. Prospective, multicenter, randomized study]. Orvosi hetilap 20030810
Randomized clinical trial of intravenous fluid replacement during bowel preparation for surgery. The British journal of surgery 20011001
Investigation of the effects of YM-31636, a novel 5-HT3 receptor agonist, on defecation in normal and constipated ferrets. European journal of pharmacology 20010720
Analytical control of a pharmaceutical formulation of sodium picosulfate by capillary zone electrophoresis. Journal of chromatography. B, Biomedical sciences and applications 20010210
The role of intestinal bacteria in the transformation of sodium picosulfate. Japanese journal of pharmacology 19920501
Toxicity study with sodium picosulfate in cultured liver cells of rabbit, rat and man. Arzneimittel-Forschung 19810101
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