Methanone, [4-[2-(1H-indazol-3-yl)ethenyl]phenyl]-1-piperazinyl-
| Title | Journal |
|---|---|
| Discovery, synthesis, and characterization of an orally bioavailable, brain penetrant inhibitor of mixed lineage kinase 3. | Journal of medicinal chemistry 20131024 |
| Comprehensive analysis of kinase inhibitor selectivity. | Nature biotechnology 20111030 |
| HDAC inhibitors potentiate the activity of the BCR/ABL kinase inhibitor KW-2449 in imatinib-sensitive or -resistant BCR/ABL+ leukemia cells in vitro and in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110515 |
| FLT3 ligand impedes the efficacy of FLT3 inhibitors in vitro and in vivo. | Blood 20110324 |
| Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry. | Chemistry & biology 20101124 |
| [FLT3 kinase inhibitors for the treatment of acute leukemia]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20100601 |
| FLT3-mutant allelic burden and clinical status are predictive of response to FLT3 inhibitors in AML. | Blood 20100218 |
| KW-2449, a novel multikinase inhibitor, suppresses the growth of leukemia cells with FLT3 mutations or T315I-mutated BCR/ABL translocation. | Blood 20090820 |