Quinuclidine
Title | Journal |
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Excited-state proton transfer and ion pair formation in a Cinchona organocatalyst. | Physical chemistry chemical physics : PCCP 20121005 |
Boron nitride nanotubes and their functionalization via quinuclidine-3-thiol with gold nanoparticles for the development and enhancement of the HPLC performance of HPLC monolithic columns. | Talanta 20120515 |
Design and synthesis of novel opioid ligands with an azabicyclo[2.2.2]octane skeleton and their pharmacologies. | Bioorganic & medicinal chemistry letters 20120415 |
Scope of stereoselective Mn-mediated radical addition to chiral hydrazones and application in a formal synthesis of quinine. | The Journal of organic chemistry 20120406 |
Asymmetric total synthesis of (+)-virosine A via sequential nucleophilic cyclizations onto an activated formamide. | The Journal of organic chemistry 20120406 |
Making SharePoint® Chemically Aware™. | Journal of cheminformatics 20120101 |
Scopolamine administration modulates muscarinic, nicotinic and NMDA receptor systems. | PloS one 20120101 |
The role of neurokinin-1 receptor in the microenvironment of inflammation and cancer. | TheScientificWorldJournal 20120101 |
Reactions of nitroxides XIII: Synthesis of the Morita-Baylis-Hillman adducts bearing a nitroxyl moiety using 4-acryloyloxy-2,2,6,6-tetramethylpiperidine-1-oxyl as a starting compound, and DABCO and quinuclidine as catalysts. | Beilstein journal of organic chemistry 20120101 |
Stepwise effective molarities in porphyrin oligomer complexes: preorganization results in exceptionally strong chelate cooperativity. | Journal of the American Chemical Society 20111228 |
Asymmetric hydrogenation on chirally modified Pt: origin of hydrogen in the N-H-O interaction between cinchonidine and ketone. | Journal of the American Chemical Society 20111214 |
New spirocyclic Δ²-isoxazoline derivatives related to selective agonists of α7 neuronal nicotinic acetylcholine receptors. | European journal of medicinal chemistry 20111201 |
Diastereodivergent asymmetric sulfa-Michael additions of α-branched enones using a single chiral organic catalyst. | Journal of the American Chemical Society 20111109 |
Identification of the best-suited leaving group for the diastereoselective synthesis of glycidic amides from stabilised ammonium ylides and aldehydes. | Organic & biomolecular chemistry 20111021 |
Designing the synthesis of catalytically active Ti-β by using various new templates in the presence of fluoride anion. | Physical chemistry chemical physics : PCCP 20110928 |
Theoretical investigation on mechanism of asymmetric Michael addition of malononitrile to chalcones catalyzed by Cinchona alkaloid aluminium(III) complex. | Organic & biomolecular chemistry 20110921 |
Effect of stereogenic centers on the self-sorting, depolymerization, and atropisomerization kinetics of porphyrin-based aggregates. | Journal of the American Chemical Society 20110810 |
Two squalene synthase inhibitors, E5700 and ER-119884, interfere with cellular proliferation and induce ultrastructural and lipid profile alterations in a Candida tropicalis strain resistant to fluconazole, itraconazole, and amphotericin B. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110801 |
Intermolecular radical addition to N-acylhydrazones as a stereocontrol strategy for alkaloid synthesis: formal synthesis of quinine. | Organic & biomolecular chemistry 20110607 |
Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl carbamates as potent and long acting muscarinic antagonists. | Bioorganic & medicinal chemistry letters 20110601 |
The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex. | Journal of inorganic biochemistry 20110301 |
Synthetic arylquinuclidine derivatives exhibit antifungal activity against Candida albicans, Candida tropicalis and Candida parapsilopsis. | Annals of clinical microbiology and antimicrobials 20110101 |
Synthesis and in vitro evaluation of novel nortropane derivatives as potential radiotracers for muscarinic m(2) receptors. | International journal of molecular imaging 20110101 |
Squalene synthase inhibitors: An update on the search for new antihyperlipidemic and antiatherosclerotic agents. | Current medicinal chemistry 20110101 |
Antiproliferative, Ultrastructural, and Physiological Effects of Amiodarone on Promastigote and Amastigote Forms of Leishmania amazonensis. | Molecular biology international 20110101 |
Structural analysis of prolyl oligopeptidases using molecular docking and dynamics: insights into conformational changes and ligand binding. | PloS one 20110101 |
Antiangiogenic properties of substituted (Z)-(±)-2-(N-benzylindol-3-ylmethylene)quinuclidin-3-ol/one analogs and their derivatives. | Bioorganic & medicinal chemistry letters 20101215 |
Surface plasmon resonance biosensor based fragment screening using acetylcholine binding protein identifies ligand efficiency hot spots (LE hot spots) by deconstruction of nicotinic acetylcholine receptor α7 ligands. | Journal of medicinal chemistry 20101014 |
Unexpected enantioseparation of mandelic acids and their derivatives on 1,2,3-triazolo-linked quinine tert-butyl carbamate anion exchange-type chiral stationary phase. | Journal of separation science 20100901 |
3-D-QSAR and docking studies on the neuronal choline transporter. | Bioorganic & medicinal chemistry letters 20100815 |
Multiple species metabolism of PHA-568487, a selective alpha 7 nicotinic acetylcholine receptor agonist. | Drug metabolism letters 20100801 |
Binary complexes of tertiary amines with phenylacetylene. Dispersion wins over electrostatics. | Physical chemistry chemical physics : PCCP 20100621 |
Using the pyridine and quinuclidine scaffolds for superbases: a DFT study. | The Journal of organic chemistry 20100416 |
Enantioselective synthesis of a chiral C(3)-symmetric bridgehead amine. | Organic letters 20100416 |
Chiral recognition in cinchona alkaloid protonated dimers: mass spectrometry and UV photodissociation studies. | The journal of physical chemistry. A 20100311 |
HPLC method for determination of fluorescence derivatives of cortisol, cortisone and their tetrahydro- and allo-tetrahydro-metabolites in biological fluids. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100201 |
SN2' versus SN2 reactivity: control of regioselectivity in conversions of Baylis-Hillman adducts. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100125 |
Cucurbit[7]uril host-guest complexes of cholines and phosphonium cholines in aqueous solution. | Organic & biomolecular chemistry 20100107 |
Delineation of downstream signalling components during acrosome reaction mediated by heat solubilized human zona pellucida. | Reproductive biology and endocrinology : RB&E 20100101 |
Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides. | Marine drugs 20100101 |
α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease. | The open medicinal chemistry journal 20100101 |
Host-guest complexes and pseudorotaxanes of cucurbit[7]uril with acetylcholinesterase inhibitors. | The Journal of organic chemistry 20091106 |
Atmospheric heterogeneous stereochemistry. | Journal of the American Chemical Society 20090930 |
Organocatalytic activity of cinchona alkaloids: which nitrogen is more nucleophilic? | The Journal of organic chemistry 20090918 |
Tertiary amine and N-heterocyclic carbene coordinated haloalanes--synthesis, structure, and application. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090914 |
Influence of peripheral groups on the physical and chemical behavior of cinchona alkaloids. | The journal of physical chemistry. B 20090827 |
Stereocontrolled synthesis and pharmacological evaluation of cis-2,6-diphenethyl-1-azabicyclo[2.2.2]octanes as lobelane analogues. | The Journal of organic chemistry 20090821 |
Fluorinated quinine alkaloids: synthesis, X-ray structure analysis and antimalarial parasite chemotherapy. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090803 |
New, improved treatments for Chagas disease: from the R&D pipeline to the patients. | PLoS neglected tropical diseases 20090701 |
Discovery of novel 1-azoniabicyclo[2.2.2]octane muscarinic acetylcholine receptor antagonists. | Journal of medicinal chemistry 20090423 |
Structure and rheology of cationic molecular hydrogels of quinuclidine grafted bile salts. Influence of the ionic strength and counter-ion type. | The journal of physical chemistry. B 20090409 |
1-Pyridine- and 1-quinuclidine-1-boraadamantane as models for derivatives of 1-borabicyclo[2.2.2]octane. Experimental and theoretical evaluation of the B-N fragment as a polar isosteric substitution for the C-C group in liquid crystal compounds. | The Journal of organic chemistry 20090220 |
Fluorescence quenching of CdSe quantum dots by tertiary amines and their surface binding effect. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090101 |
Efficient N-arylation/dealkylation of electron deficient heteroaryl chlorides and bicyclic tertiary amines under microwave irradiation. | Journal of combinatorial chemistry 20090101 |
Management of postoperative nausea and vomiting: focus on palonosetron. | Therapeutics and clinical risk management 20090101 |
Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. | Interdisciplinary perspectives on infectious diseases 20090101 |
The solubilisation of boar sperm membranes by different detergents - a microscopic, MALDI-TOF MS, (31)P NMR and PAGE study on membrane lysis, extraction efficiency, lipid and protein composition. | Lipids in health and disease 20090101 |
High-frequency Broadband Modulations of Electroencephalographic Spectra. | Frontiers in human neuroscience 20090101 |
Multiple pharmacophores for the selective activation of nicotinic alpha7-type acetylcholine receptors. | Molecular pharmacology 20081201 |
Use of molecular electrostatic potential for quantitative assessment of inductive effect. | Physical chemistry chemical physics : PCCP 20081121 |
Polyepichlorhydrin membranes for alkaline fuel cells: sorption and conduction properties. | The journal of physical chemistry. B 20081002 |
Interaction energies and dynamics of acid-base pairs isolated in cavitands. | The Journal of organic chemistry 20080905 |
The crystal structure of halofantrine-ferriprotoporphyrin IX and the mechanism of action of arylmethanol antimalarials. | Journal of inorganic biochemistry 20080801 |
Application of the PM6 method to modeling the solid state. | Journal of molecular modeling 20080601 |
(R)-(-)-3-Hydroxy-quinuclidinium chloride. | Acta crystallographica. Section E, Structure reports online 20080501 |
3-Chloro-quinuclidinium chloride. | Acta crystallographica. Section E, Structure reports online 20080501 |
alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues. | British journal of pharmacology 20080301 |
Quinuclidine complex with alpha-cyclodextrin: a diffusion and 13C NMR relaxation study. | Magnetic resonance in chemistry : MRC 20080301 |
Synthetic efforts for stereo structure determination of cytotoxic marine natural product pericosines as metabolites of Periconia sp. from sea hare. | International journal of molecular sciences 20080301 |
1-[(Diethyl-amino-carbon-yl)meth-yl]-2-[hydr-oxy(6-methoxy-quinolin-4-yl)meth-yl]-5-vinyl-1-azoniabicyclo-[2.2.2]octane chloride monohydrate. | Acta crystallographica. Section E, Structure reports online 20080201 |
Huge deuterated effect on permittivity in a metal-organic framework. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
Mixed-ligand metal-organic frameworks with large pores: gas sorption properties and single-crystal-to-single-crystal transformation on guest exchange. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
Synthesis and characterization of new nitrogen-donor-stabilized N-silylphosphoranimine cations. | Inorganic chemistry 20071112 |
Adducts of rhodium(II) tetraacetate with some nitrogenous organic ligands: application of natural abundance 15N and 13C CPMAS NMR spectroscopy. | Solid state nuclear magnetic resonance 20071001 |
Role of guiding groups in cinchona-modified platinum for controlling the sense of enantiodifferentiation in the hydrogenation of ketones. | Journal of the American Chemical Society 20070829 |
Metabolism, pharmacokinetics, and excretion of a nonpeptidic substance P receptor antagonist, ezlopitant, in normal healthy male volunteers: characterization of polar metabolites by chemical derivatization with dansyl chloride. | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
Molecular structures of free quinuclidine and its adducts with metal trihydrides, MH3 (M=B, Al or Ga), studied by gas-phase electron diffraction, X-ray diffraction and quantum chemical calculations. | Dalton transactions (Cambridge, England : 2003) 20070507 |
Quinuclidines as selective agonists for alpha-7 nicotinic acetylcholine receptors. | Bioorganic & medicinal chemistry letters 20070315 |
Investigation of the stability of the M-H-B bond in borane sigma complexes [M(CO)5(eta1-BH2R.L)] and [CpMn(CO)2(eta1-BH2R.L)] (M=Cr, W; L=tertiary amine or phosphine): substituent and Lewis base effects. | Chemistry (Weinheim an der Bergstrasse, Germany) 20070101 |
Effectiveness of low-dose doxycycline (LDD) on clinical symptoms of Sjögren's syndrome: a randomized, double-blind, placebo controlled cross-over study. | Journal of negative results in biomedicine 20070101 |
The nature of the chemical bond in linear three-body systems: from i3- to mixed chalcogen/halogen and trichalcogen moieties. | Bioinorganic chemistry and applications 20070101 |
A synthetic mimic of protein inner space: buried polar interactions in a deep water-soluble host. | Journal of the American Chemical Society 20061206 |
Synthetic studies on quinine: quinuclidine construction via a ketone enolate regio- and diastereoselective Pd-mediated allylic alkylation. | Organic letters 20060831 |
Method for enantiomeric purity of a quinuclidine candidate drug by capillary electrophoresis. | Journal of separation science 20060801 |
RP-HPLC method with fluorescence detection for determination of small quantities of triamcinolone in plasma in presence of endogenous steroids after derivatization with 9-anthroyl nitrile; pharmacokinetic studies. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724 |
Antiproliferative activities of two novel quinuclidine inhibitors against Toxoplasma gondii tachyzoites in vitro. | The Journal of antimicrobial chemotherapy 20060701 |
A generalized two-point H-bonding model for catalytic stereoselective hydrogenation of activated ketones on chirally modified platinum. | Journal of the American Chemical Society 20060614 |
Pyridinium, imidazolium and quinuclidinium compounds: toxicity and antidotal effects against the nerve agents Tabun and Soman. | Arhiv za higijenu rada i toksikologiju 20060601 |
Perturbation of adsorbed CO by amine derivatives coadsorbed on the gamma-Al2O3 surface: FTIR and first principles studies. | The journal of physical chemistry. B 20060316 |
Potent anti-muscarinic activity in a novel series of quinuclidine derivatives. | Bioorganic & medicinal chemistry letters 20060115 |
m-Calpain is required for preimplantation embryonic development in mice. | BMC developmental biology 20060101 |
Zona pellucida from fertilised human oocytes induces a voltage-dependent calcium influx and the acrosome reaction in spermatozoa, but cannot be penetrated by sperm. | BMC developmental biology 20060101 |
Structure and reactivity of trans-bis[2-(2-chloroethyl)pyridine]palladium chloride (1). A study on the elimination reaction of 1 and 2-(2-chloroethyl)pyridine induced by quinuclidine in acetonitrile. | The Journal of organic chemistry 20051223 |
Rate-limiting proton-transfer in the sigma-adduct forming reactions of 1,3,5-trinitrobenzene and 4-nitrobenzofuroxan with substituted anilines in dimethyl sulfoxide. | Organic & biomolecular chemistry 20051107 |
High affinity ligands for the alpha7 nicotinic receptor that show no cross-reactivity with the 5-HT3 receptor. | Bioorganic & medicinal chemistry letters 20051101 |
Synthesis and antimuscarinic properties of quinuclidin-3-yl 1,2,3,4-tetrahydroisoquinoline-2-carboxylate derivatives as novel muscarinic receptor antagonists. | Journal of medicinal chemistry 20051020 |
A deep cavitand provides a structured environment for the Menschutkin reaction. | Journal of the American Chemical Society 20050817 |
Mono- and digallane complexes of a tridentate amido-diamine ligand. | Chemical communications (Cambridge, England) 20050721 |
Competition at chiral metal surfaces: fundamental aspects of the inversion of enantioselectivity in hydrogenations on platinum. | Journal of the American Chemical Society 20050615 |
Synthesis, X-ray crystal structures, and gas sorption properties of pillared square grid nets based on paddle-wheel motifs: implications for hydrogen storage in porous materials. | Chemistry (Weinheim an der Bergstrasse, Germany) 20050606 |
Orientational isomers of alpha-cyclodextrin [2]semi-rotaxanes with asymmetric dicationic threads. | Organic & biomolecular chemistry 20050421 |
3-Aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione for circumvention of anticancer drug resistance. | Bioorganic & medicinal chemistry 20050315 |
Homotryptamines as potent and selective serotonin reuptake inhibitors (SSRIs). | Bioorganic & medicinal chemistry letters 20050315 |
Synthesis and photophysical properties of models for twisted PRODAN and dimethylaminonaphthonitrile. | The journal of physical chemistry. A 20050224 |
Structure-property relationship in py-hexahydrocinchonidine diastereomers: ab initio and NMR study. | The journal of physical chemistry. A 20050210 |
Cobalt complexes with cinchonidine and quinidine: effect of C8/C9 stereochemistry and 6'-substitution on intermolecular interactions. | Chirality 20050201 |
Synthesis and biodistribution of radiolabeled alpha 7 nicotinic acetylcholine receptor ligands. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20050201 |
Rigidified tripodal chiral ligands in the asymmetric recognition of amino compounds. | Chirality 20050101 |
Synthesis and biological evaluation of quinuclidine derivatives incorporating phenothiazine moieties as squalene synthase inhibitors. | Chemical & pharmaceutical bulletin 20041001 |
Effect of humanin analogues on experimentally induced impairment of spatial memory in rats. | Journal of peptide science : an official publication of the European Peptide Society 20041001 |
Acrylamide in the Baylis-Hillman reaction: expanded reaction scope and the unexpected superiority of DABCO over more basic tertiary amine catalysts. | The Journal of organic chemistry 20040917 |
Synthesis and evaluation of phenylcarbamate derivatives as ligands for nicotinic acetylcholine receptors. | Bioorganic & medicinal chemistry 20040915 |
Me2AlCH2PMe2: a new, bifunctional cocatalyst for the Ni(II)-catalyzed oligomerization of PhSiH3. | Journal of the American Chemical Society 20040721 |
Reduction reactions of a 1,3,5-triphosphabenzene. | Dalton transactions (Cambridge, England : 2003) 20040707 |
Direct STM investigation of cinchona alkaloid adsorption on Cu(III). | Langmuir : the ACS journal of surfaces and colloids 20040413 |
Mechanisms of acid-base catalysis of beta-elimination reactions in systems activated by a pyridine ring. | The Journal of organic chemistry 20040402 |
Crystal and molecular structures of new enantiopure quinuclidines. | Chirality 20040301 |
Generation and coupling of [Mn(dmpe)2(C triple bond CR)(C triple bond C)]* radicals producing redox-active C4-bridged rigid-rod complexes. | Chemistry (Weinheim an der Bergstrasse, Germany) 20031215 |
Solvent-stabilized molecular capsules. | The Journal of organic chemistry 20030822 |
Cinchona alkaloid derived ligands in catalytic asymmetric transfer hydrogenation. | Organic & biomolecular chemistry 20030721 |
Sensitive determination of alkoxyethanols by pre-column derivatization with 1-anthroylnitrile and reversed-phase high-performance liquid chromatography. | Journal of chromatography. A 20030711 |
Age-related decreases in the response of aquaporin-5 to acetylcholine in rat parotid glands. | Journal of dental research 20030601 |
Syntheses and biological evaluation of novel quinuclidine derivatives as squalene synthase inhibitors. | Bioorganic & medicinal chemistry 20030529 |
3D QSAR analyses-guided rational design of novel ligands for the (alpha4)2(beta2)3 nicotinic acetylcholine receptor. | Journal of medicinal chemistry 20030522 |
Correlation between pK(a) and reactivity of quinuclidine-based catalysts in the Baylis-Hillman reaction: discovery of quinuclidine as optimum catalyst leading to substantial enhancement of scope. | The Journal of organic chemistry 20030207 |
Daphcalycine, a novel heptacycle fused ring system alkaloid from Daphniphyllum calycinum. | The Journal of organic chemistry 20030124 |
The relationship of physico-chemical properties and structure to the differential antiplasmodial activity of the cinchona alkaloids. | Malaria journal 20030101 |
Adsorption mode of cinchonidine on Cu(111) surface. | Journal of the American Chemical Society 20021204 |
Photoelectron spectra and electronic structure of some diastereomeric quinuclidine derivatives. | Chemphyschem : a European journal of chemical physics and physical chemistry 20021115 |
The inhibitory effects of tramadol on muscarinic receptor-induced responses in Xenopus oocytes expressing cloned M(3) receptors. | Anesthesia and analgesia 20021101 |
[Cevimeline hydrochloride hydrate (Saligren capsule 30 mg): a review of its pharmacological profiles and clinical potential in xerostomia]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021001 |
Metal-switching and self-inclusion of functional cavitands. | Journal of the American Chemical Society 20020904 |
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT(3) receptor. | Bioorganic & medicinal chemistry 20020801 |
The Interactions of the 5-HT(3) receptor with arylpiperazine, tropane, and quinuclidine ligands. | Current topics in medicinal chemistry 20020601 |
Aromatic 4-tetrahydropyranyl and 4-quinuclidinyl cations. Linking Prins with Cope and Grob. | Journal of the American Chemical Society 20020508 |
Formation and stability of enolates of acetamide and acetate anion: an Eigen plot for proton transfer at alpha-carbonyl carbon. | Journal of the American Chemical Society 20020327 |
Practical Os/Cu-cocatalyzed air oxidation of allyl and benzyl alcohols at room temperature and atmospheric pressure. | Organic letters 20020321 |
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities. | Bioorganic & medicinal chemistry 20020301 |
Metal ligation regulates conformational equilibria and binding properties of cavitands. | Organic letters 20020207 |
Quinuclidinone O-Alkynyloximes with muscarinic agonist activity. | Bioorganic & medicinal chemistry 20020101 |
New crystalline complex of quinine and quinidine. | Enantiomer 20020101 |
Cinchoninium L-tartrate tetrahydrate. | Acta crystallographica. Section C, Crystal structure communications 20011201 |
A self-folding metallocavitand. | Journal of the American Chemical Society 20011017 |
Oxidation of NADH by chloramines and chloramides and its activation by iodide and by tertiary amines. | Archives of biochemistry and biophysics 20010915 |
Design and pharmacology of quinuclidine derivatives as M2-selective muscarinic receptor ligands. | Bioorganic & medicinal chemistry letters 20010507 |
Syntheses of the first amine-dicarboxyboranes and their bis(methylester) and bis(N-ethylamide) derivatives. | Inorganic chemistry 20010409 |
The 5-HT3 antagonist tropisetron (ICS 205-930) is a potent and selective alpha7 nicotinic receptor partial agonist. | Bioorganic & medicinal chemistry letters 20010212 |
Gallane complexes with amido-amine ligands. | Inorganic chemistry 20010115 |
SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP. | European journal of nuclear medicine 20010101 |
Crystal and molecular structure of a new cobalt complex of quinine. | Enantiomer 20010101 |