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PENICILLIN V

CAS No.:
87-08-1
Catalog Number:
AG00GROE
Molecular Formula:
Molecular Weight:
Pack Size
Purity
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Product Description
Catalog Number:
AG00GROE
Chemical Name:
PENICILLIN V
CAS Number:
87-08-1
MDL Number:
MFCD00070096
IUPAC Name:
(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
InChI:
InChI=1S/C16H18N2O5S/c1-16(2)12(15(21)22)18-13(20)11(14(18)24-16)17-10(19)8-23-9-6-4-3-5-7-9/h3-7,11-12,14H,8H2,1-2H3,(H,17,19)(H,21,22)/t11-,12+,14-/m1/s1
InChI Key:
BPLBGHOLXOTWMN-MBNYWOFBSA-N
UNII:
Z61I075U2W
Properties
Complexity:
547  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Defined Bond Stereocenter Count:
0
Exact Mass:
350.094g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
350.389g/mol
Monoisotopic Mass:
350.094g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
121A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.1  
Literature
Title Journal
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Voltammetric determination of penicillin V in pharmaceutical formulations and human urine using a boron-doped diamond electrode. Bioelectrochemistry (Amsterdam, Netherlands) 20121201
Toxicity of untreated and ozone-treated oil sands process-affected water (OSPW) to early life stages of the fathead minnow (Pimephales promelas). Water research 20121201
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The problem of confounding in studies of the effect of maternal drug use on pregnancy outcome. Obstetrics and gynecology international 20120101
Proteomics shows new faces for the old penicillin producer Penicillium chrysogenum. Journal of biomedicine & biotechnology 20120101
An overview of the evidence and mechanisms of herb-drug interactions. Frontiers in pharmacology 20120101
Once weekly azithromycin in secondary prevention of rheumatic fever. Indian heart journal 20120101
An acute case of herpes zoster ophthalmicus with ophthalmoplegia. Case reports in ophthalmological medicine 20120101
Nonsteroidal anti-inflammatory drugs misleading the diagnosis of periapical abscess. Journal of natural science, biology, and medicine 20120101
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Colonization by Candida in children with cancer, children with cystic fibrosis, and healthy controls. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20111201
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[Children prefer bottled amoxicillin]. Ugeskrift for laeger 20101213
A novel homologous dominant selection marker for genetic transformation of Penicillium chrysogenum: overexpression of squalene epoxidase-encoding ergA. Journal of biotechnology 20101101
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A prospective multi-center trial of Escherichia coli extract for the prophylactic treatment of patients with chronically recurrent cystitis. Journal of Korean medical science 20100301
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Hand dermatitis and lymphoedema. The British journal of dermatology 20090701
Specific IgG antibodies in sera in patients with penicillin allergy. Clinical and experimental medicine 20090601
Hypersensitivity reactions to penicillins: studies in a group of patients with negative benzylpenicillin G skin test. Journal of clinical pharmacy and therapeutics 20090601
Determination of arylamines and aminopyridines in pharmaceutical products using in-situ derivatization and liquid chromatography-mass spectrometry. Journal of chromatography. A 20090417
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The specificity of tests for anti-beta-lactam IgE antibodies declines progressively with increase of total serum IgE. Wiener klinische Wochenschrift 20090101
Appropriate antibiotic prescribing for the general dentist. General dentistry 20090101
[An exceptional component C3 deficiency revealed by serum protein electrophoresis]. Annales de biologie clinique 20090101
Comparative Study of 5-Day and 10-Day Cefditoren Pivoxil Treatments for Recurrent Group A beta-Hemolytic Streptococcus pharyngitis in Children. International journal of pediatrics 20090101
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Treatment of Lyme borreliosis. Arthritis research & therapy 20090101
[Treatment of erythema migrans]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20081218
Effects of treatment with antimicrobial agents on the human colonic microflora. Therapeutics and clinical risk management 20081201
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry 20081113
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Transient monocular vision loss from acute rheumatic fever. Pediatric cardiology 20080901
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A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine. Drug metabolism and disposition: the biological fate of chemicals 20080801
Once-daily amoxicillin versus twice-daily penicillin V in group A beta-haemolytic streptococcal pharyngitis. Archives of disease in childhood 20080601
Antimicrobial susceptibility of periodontopathogenic bacteria. The Journal of antimicrobial chemotherapy 20080501
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Oral bisphosphonate associated osteonecrosis of the jaws: three case reports. British dental journal 20070728
Aminopenicillin-induced exanthema allows treatment with certain cephalosporins or phenoxymethyl penicillin. The Journal of antimicrobial chemotherapy 20070701
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Synthesis and in vitro study of novel 7-O-acyl derivatives of Oroxylin A as antibacterial agents. Bioorganic & medicinal chemistry letters 20050901
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Optimization of culture medium and conditions for penicillin acylase production by Streptomyces lavendulae ATCC 13664. Applied biochemistry and biotechnology 20050801
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Penicillin degradation catalysed by Zn(II) ions in methanol. International journal of biological macromolecules 20031201
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Antibiotic susceptibility of bacteria associated with endodontic abscesses. Journal of endodontics 20030101
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Relief of symptoms in patients with group A beta-hemolytic streptococcus tonsillopharyngitis: comparison between telithromycin and penicillin V. Scandinavian journal of infectious diseases 20030101
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Recurrent pneumococcal meningitis in a splenectomised HIV-infected patient. Annals of clinical microbiology and antimicrobials 20030101
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Solitary borrelial lymphocytoma in adult patients. Wiener klinische Wochenschrift 20020731
The fecal microflora of 1-3-month-old infants during treatment with eight oral antibiotics. Infection 20020601
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Comparison of two dosages of azithromycin for three days versus penicillin V for ten days in acute group A streptococcal tonsillopharyngitis. The Pediatric infectious disease journal 20020401
Azithromycin versus penicillin V for treatment of acute group A streptococcal pharyngitis. The Pediatric infectious disease journal 20020401
Substrate specificity of penicillin acylase from Streptomyces lavendulae. Biochemical and biophysical research communications 20020301
Brain abscess due to Capnocytophaga species, Actinomyces species, and Streptococcus intermedius in a patient with cyanotic congenital heart disease. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20020301
Five day clarithromycin modified release versus 10 day penicillin V for group A streptococcal pharyngitis: a multi-centre, open-label, randomized study. The Journal of antimicrobial chemotherapy 20020201
Non-myeloablative bone marrow transplantation in an adult with Wiskott-Aldrich syndrome. British journal of haematology 20020201
Comparison of aqueous and nonaqueous carrier electrolytes for the separation of penicillin V and related substances by capillary electrophoresis with UV and mass spectrometric detection. Electrophoresis 20020201
Anaphylactic shock due to cefuroxime in a patient taking penicillin prophylaxis. Paediatric anaesthesia 20020101
Antibiotic prescription rates vary markedly between 13 European countries. Scandinavian journal of infectious diseases 20020101
Antibiotic prescribing in outpatients: a 1-week diagnosis-prescribing study in 5 counties in Sweden. Scandinavian journal of infectious diseases 20020101
Liquid chromatographic determination of ampicillin residues in porcine muscle tissue by a multipenicillin analytical method: European Collaborative Study. Journal of AOAC International 20020101
A systematic review of antistreptococcal interventions for guttate and chronic plaque psoriasis. The British journal of dermatology 20011201
Unexplained reduced microbiological efficacy of intramuscular benzathine penicillin G and of oral penicillin V in eradication of group a streptococci from children with acute pharyngitis. Pediatrics 20011101
Short-course therapy with cefaclor for treatment of streptococcal pharyngotonsillitis. International journal of antimicrobial agents 20011001
Determination of benzylpenicillin, oxacillin, cloxacillin, and dicloxacillin in cows' milk by ion-pair high-performance liquid chromatography after precolumn derivatization. Fresenius' journal of analytical chemistry 20010901
[Five days ceftibuten versus 10 days penicillin in the treatment of 2099 patients with A-streptococcal tonsillopharyngitis]. Fortschritte der Medizin. Originalien 20010719
Paediatric antibiotic prescribing by general dental practitioners in England. International journal of paediatric dentistry 20010701
A novel microphysiometer based on MLAPS for drugs screening. Biosensors & bioelectronics 20010601
[Treatment of group A streptococcal tonsillopharyngitis. 5 days cephalosporin is as effective as 10 days penicillin]. MMW Fortschritte der Medizin 20010503
Probing the penicillin sidechain selectivity of recombinant deacetoxycephalosporin C synthase. Cellular and molecular life sciences : CMLS 20010501
[Angina tonsillaris in children. Penicillin V can not be recommended here]. MMW Fortschritte der Medizin 20010322
Application of ion-exchange cartridge clean-up in food analysis IV. Confirmatory assay of benzylpenicillin, phenoxymethylpenicillin, oxacillin, cloxacillin, nafcillin and dicloxacillin, in bovine tissues by liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of chromatography. A 20010316
Isolation of Borrelia burgdorferi sensu lato from blood of children with solitary erythema migrans. The Pediatric infectious disease journal 20010301
Fluorescent Bocillins: synthesis and application in the detection of penicillin-binding proteins. Electrophoresis 20010301
Quantitative analysis of Penicillium chrysogenum Wis54-1255 transformants overexpressing the penicillin biosynthetic genes. Biotechnology and bioengineering 20010220
Effect of recolonisation with 'interfering' alpha streptococci on recurrences of acute and secretory otitis media in children: randomised placebo controlled trial. BMJ (Clinical research ed.) 20010127
Biphasic illness pattern due to early relapse in Japanese-B virus encephalitis. Journal of the neurological sciences 20010115
Toxic epidermal necrolysis in a patient with severe aplastic anemia treated with cyclosporin A and G-CSF. Journal of medicine 20010101
Myopericarditis associated with streptococcal tonsilitis. The Israel Medical Association journal : IMAJ 20010101
Telithromycin. Drugs 20010101
Antibacterial drugs prescribed for dogs and cats in Sweden and Norway 1990-1998. Acta veterinaria Scandinavica 20010101
Penicillin V production by Penicillium chrysogenum in the presence of Fe3+ and in low-iron culture medium. Folia microbiologica 20010101
Fine structural recognition specificities of IgE antibodies distinguishing amoxicilloyl and amoxicillanyl determinants in allergic subjects. Journal of molecular recognition : JMR 20010101
Efficacy of short-course therapy with the ketolide telithromycin compared with 10 days of penicillin V for the treatment of pharyngitis/tonsillitis. Scandinavian journal of infectious diseases 20010101
Antibiotics in treating oral-facial infections of odontogenic origin: an update. General dentistry 20010101
Antigen-dependent and -independent IFN-gamma modulation by penicillins. Journal of immunology (Baltimore, Md. : 1950) 19990115
Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 19980501
Anti-IL-4 monoclonal antibody prevents antibiotics-induced active fatal anaphylaxis. Journal of immunology (Baltimore, Md. : 1950) 19970515
T cell recognition of penicillin G: structural features determining antigenic specificity. European journal of immunology 19960101
Impairment of renal function after treatment of a burn patient with diclofenac, a non-steroidal antiinflammatory drug. Burns : journal of the International Society for Burn Injuries 19950901
5-day cefixime therapy for bacterial pharyngitis and/or tonsillitis: comparison with 10-day penicillin V therapy. Cefixime Study Group. Infection 19950101
Loracarbef versus penicillin VK in the treatment of streptococcal pharyngitis and tonsillitis in an adult population. The American journal of medicine 19920622
Identification of penicillin allergenic determinants that bind IgE antibodies in the sera of subjects with penicillin allergy. Molecular immunology 19901101
Penicillin anaphylaxis. The American journal of emergency medicine 19860501
Effect of drugs influencing synthesis of prostaglandins on haloperidol-induced catalepsy in rats. Indian journal of physiology and pharmacology 19840101
[Leukocytoclastic vasculitis due to drug allergy presenting as generalized pustular exanthema]. Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 19810901
Assessment of the 'E' book as a tool for drug monitoring. Journal of epidemiology and community health 19810301
Unusual evidence of myocardial involvement during a hypersensitivity reaction to oral penicillin. Israel journal of medical sciences 19780801
[Immune hemolytic anemia and thrombocytopenia after peroral therapy with a penicillin derivative (phenoxymethylpenicillin)]. Bilten za hematologiju i transfuziju 19770101
Haemolytic anaemia due to penicillin. British medical journal 19750920
Acute haemolytic anaemia due to IgM penicillin antibody in a 3-year-old child: a sequel to oral penicillin. Journal of clinical pathology 19750401
[The antiviral activity of the antibiotics beromycin and carminomycin]. Antibiotiki 19740201
Comparative convulsant activity of various penicillins after intracerebral injection in mice. The Journal of pharmacy and pharmacology 19730201
Properties