Home Other Building Blocks 6,4''-DIHYDROXYAURONE

6,4''-DIHYDROXYAURONE

CAS No.:
5786-54-9
Catalog Number:
AG00EIMD
Molecular Formula:
C15H10O4
Molecular Weight:
254.2375
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$210
- +
10mg
99%
1 week
United States
$307
- +
50mg
99%
1 week
United States
$543
- +
100mg
99%
1 week
United States
$821
- +
200mg
99%
1 week
United States
$1098
- +
500mg
99%
1 week
United States
$2140
- +
Product Description
Catalog Number:
AG00EIMD
Chemical Name:
6,4''-DIHYDROXYAURONE
CAS Number:
5786-54-9
Molecular Formula:
C15H10O4
Molecular Weight:
254.2375
MDL Number:
MFCD00135406
IUPAC Name:
(2Z)-6-hydroxy-2-[(4-hydroxyphenyl)methylidene]-1-benzofuran-3-one
InChI:
InChI=1S/C15H10O4/c16-10-3-1-9(2-4-10)7-14-15(18)12-6-5-11(17)8-13(12)19-14/h1-8,16-17H/b14-7-
InChI Key:
KEZLDSPIRVZOKZ-AUWJEWJLSA-N
SMILES:
Oc1ccc(cc1)/C=C/1\Oc2c(C1=O)ccc(c2)O
NSC Number:
356828
Properties
Complexity:
382  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
254.058g/mol
Formal Charge:
0
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
254.241g/mol
Monoisotopic Mass:
254.058g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
66.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.9  
Literature
Title Journal
Discovery of naturally occurring aurones that are potent allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase. Journal of medicinal chemistry 20110801
Synthesis of aurones and their inhibitory effects on nitric oxide and PGE2 productions in LPS-induced RAW 264.7 cells. Bioorganic & medicinal chemistry letters 20110801
1-Azaaurones derived from the naturally occurring aurones as potential antimalarial drugs. Bioorganic & medicinal chemistry 20100801
Functionalized aurones as inducers of NAD(P)H:quinone oxidoreductase 1 that activate AhR/XRE and Nrf2/ARE signaling pathways: synthesis, evaluation and SAR. European journal of medicinal chemistry 20100701
Integrated metabolite and transcript profiling identify a biosynthetic mechanism for hispidol in Medicago truncatula cell cultures. Plant physiology 20091101
Discovery of benzylidenebenzofuran-3(2H)-one (aurones) as inhibitors of tyrosinase derived from human melanocytes. Journal of medicinal chemistry 20060112
Evaluation of in vitro activity of aurones and related compounds against Cryptosporidium parvum. Planta medica 20011101
Properties